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ENCODE: H3K4me1 ChIP-Seq of primary human cells
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Results for NKX1-1

Z-value: 0.47

Motif logo

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Transcription factors associated with NKX1-1

Gene Symbol Gene ID Gene Info
NKX1-1
ENSG00000235608.1 NK1 homeobox 1

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE Gene Distance Association probability Pearson corr. coef. P-value Plot
chr4_1397108_1397259NKX1-129360.2045020.781.2e-02Click!
chr4_1523048_1523199NKX1-11230040.0416550.732.5e-02Click!
chr4_1396773_1396924NKX1-132710.1929710.665.5e-02Click!
chr4_1523224_1523438NKX1-11232120.0415410.501.7e-01Click!
chr4_1396296_1396451NKX1-137460.1810790.314.2e-01Click!

Activity of the NKX1-1 motif across conditions

Conditions sorted by the z-value of the NKX1-1 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE) Target Score Top associated gene Gene Info Distance of CRE to TSS CRE/Gene association probability
chr10_11155205_11156000 0.30 CELF2-AS2
 CELF2 antisense RNA 2
 15166
 0.21
chr10_6642170_6642420 0.22 PRKCQ
 protein kinase C, theta
 20032
 0.28
chr10_6087007_6087203 0.21 IL2RA
 interleukin 2 receptor, alpha
 17148
 0.13
chr4_68440895_68441046 0.21 STAP1
 signal transducing adaptor family member 1
 16524
 0.2
chr2_202077121_202077490 0.19 CASP8
 caspase 8, apoptosis-related cysteine peptidase
 20861
 0.15
chr5_61873952_61874158 0.18 LRRC70
 leucine rich repeat containing 70
 507
 0.52
chr5_49959500_49959784 0.18 PARP8
 poly (ADP-ribose) polymerase family, member 8
 2091
 0.49
chr11_118097693_118098499 0.17 AMICA1
 adhesion molecule, interacts with CXADR antigen 1
 2287
 0.23
chr9_71643128_71643290 0.17 FXN
 frataxin
 6966
 0.23
chr9_134852338_134852532 0.16 MED27
 mediator complex subunit 27
 102818
 0.07
chr12_104863294_104863607 0.16 CHST11
 carbohydrate (chondroitin 4) sulfotransferase 11
 12671
 0.27
chr10_44277312_44277574 0.16 ZNF32
 zinc finger protein 32
 133139
 0.05
chr3_121990121_121990409 0.16 ENSG00000221474
 .
 10435
 0.16
chr9_130623880_130624317 0.16 ENG
 endoglin
 7063
 0.08
chr1_173487659_173487906 0.15 RP3-436N22.3
36608
 0.14
chr8_90733427_90733578 0.15 RIPK2
 receptor-interacting serine-threonine kinase 2
 36473
 0.23
chr18_74872232_74872572 0.15 MBP
 myelin basic protein
 27602
 0.24
chr16_72887246_72887397 0.15 ENSG00000251868
 .
 31430
 0.16
chr17_33850293_33850718 0.15 RP11-1094M14.5
13216
 0.11
chr8_19552777_19552928 0.15 CSGALNACT1
 chondroitin sulfate N-acetylgalactosaminyltransferase 1
 12580
 0.3
chr18_77128932_77129101 0.15 RP11-800A18.4
25044
 0.17
chr12_109290560_109290711 0.15 DAO
 D-amino-acid oxidase
 16508
 0.15
chr10_87985596_87985747 0.14 ENSG00000199104
 .
 38874
 0.19
chr10_5858173_5858324 0.14 GDI2
 GDP dissociation inhibitor 2
 1956
 0.34
chr1_172666866_172667065 0.14 FASLG
 Fas ligand (TNF superfamily, member 6)
 38807
 0.19
chr3_47367800_47368066 0.14 KIF9
 kinesin family member 9
 42992
 0.11
chr3_5469487_5469638 0.14 ENSG00000241227
 .
 174654
 0.03
chr7_37460206_37460357 0.14 ENSG00000200113
 .
 1050
 0.54
chr9_93558751_93558954 0.14 SYK
 spleen tyrosine kinase
 5217
 0.35
chr10_7347823_7348170 0.14 SFMBT2
 Scm-like with four mbt domains 2
 102711
 0.08
chr20_57844647_57845067 0.14 EDN3
 endothelin 3
 30625
 0.2
chr20_61611257_61611490 0.14 SLC17A9
 solute carrier family 17 (vesicular nucleotide transporter), member 9
 26975
 0.13
chr1_206225703_206225865 0.14 AVPR1B
 arginine vasopressin receptor 1B
 1808
 0.28
chr14_68808631_68808789 0.14 RAD51B
 RAD51 paralog B
 69517
 0.12
chr14_71512203_71512354 0.13 PCNX
 pecanex homolog (Drosophila)
 2399
 0.43
chr1_117056573_117057331 0.13 CD58
 CD58 molecule
 30260
 0.14
chr2_30557961_30558163 0.13 ENSG00000221377
 .
 97252
 0.07
chr3_15334844_15335113 0.13 SH3BP5
 SH3-domain binding protein 5 (BTK-associated)
 17426
 0.13
chr7_139555811_139556201 0.13 TBXAS1
 thromboxane A synthase 1 (platelet)
 26896
 0.22
chr2_177805314_177805465 0.13 ENSG00000206866
 .
 10571
 0.29
chr11_103747159_103747310 0.13 ENSG00000264200
 .
 26600
 0.23
chr9_36218264_36218537 0.13 CLTA
 clathrin, light chain A
 27440
 0.14
chr21_36276778_36277002 0.13 RUNX1
 runt-related transcription factor 1
 14803
 0.29
chr17_38376031_38376425 0.13 WIPF2
 WAS/WASL interacting protein family, member 2
 124
 0.95
chr20_11150036_11150187 0.13 C20orf187
 chromosome 20 open reading frame 187
 141300
 0.05
chr2_38151916_38152120 0.13 RMDN2
 regulator of microtubule dynamics 2
 444
 0.89
chr2_62433452_62433745 0.13 ENSG00000266097
 .
 637
 0.7
chr20_24936381_24936539 0.13 CST7
 cystatin F (leukocystatin)
 6594
 0.2
chr8_141180516_141180667 0.13 C8orf17
 chromosome 8 open reading frame 17
 237175
 0.02
chr15_40489916_40490242 0.13 PAK6
 p21 protein (Cdc42/Rac)-activated kinase 6
 19550
 0.12
chr5_75600048_75600202 0.13 RP11-466P24.6
7162
 0.3
chr17_4615808_4616101 0.13 ARRB2
 arrestin, beta 2
 1960
 0.15
chr3_193494689_193494840 0.13 ENSG00000243991
 .
 36254
 0.2
chr12_29393294_29393456 0.13 FAR2
 fatty acyl CoA reductase 2
 16697
 0.24
chr14_65297386_65297537 0.12 SPTB
 spectrin, beta, erythrocytic
 7595
 0.2
chr16_73092870_73093114 0.12 ZFHX3
 zinc finger homeobox 3
 605
 0.79
chr14_70091720_70091880 0.12 KIAA0247
 KIAA0247
 13487
 0.23
chr4_15471936_15472128 0.12 CC2D2A
 coiled-coil and C2 domain containing 2A
 395
 0.86
chr18_9404689_9404840 0.12 TWSG1
 twisted gastrulation BMP signaling modulator 1
 69916
 0.08
chr1_245344487_245344638 0.12 KIF26B
 kinesin family member 26B
 26275
 0.17
chr22_21922789_21923120 0.12 UBE2L3
 ubiquitin-conjugating enzyme E2L 3
 928
 0.38
chr16_85337462_85337809 0.12 ENSG00000266307
 .
 2296
 0.37
chr5_36842497_36842706 0.12 NIPBL
 Nipped-B homolog (Drosophila)
 34260
 0.23
chrX_19795655_19795879 0.12 SH3KBP1
 SH3-domain kinase binding protein 1
 22102
 0.26
chr5_64332628_64332878 0.12 ENSG00000207439
 .
 86443
 0.1
chr6_53109375_53109667 0.12 ENSG00000206908
 .
 25462
 0.15
chr7_37697149_37697300 0.12 GPR141
 G protein-coupled receptor 141
 26176
 0.2
chr6_117804732_117805043 0.12 DCBLD1
 discoidin, CUB and LCCL domain containing 1
 1062
 0.49
chr20_31149162_31149437 0.12 RP11-410N8.3
404
 0.82
chr6_15078179_15078392 0.12 ENSG00000242989
 .
 34914
 0.21
chr3_151963328_151963479 0.12 MBNL1
 muscleblind-like splicing regulator 1
 22426
 0.21
chr5_61613165_61613316 0.12 KIF2A
 kinesin heavy chain member 2A
 5600
 0.28
chr14_101601175_101601448 0.12 ENSG00000206761
 .
 10721
 0.06
chr19_47948776_47948927 0.12 MEIS3
 Meis homeobox 3
 26071
 0.11
chr14_77873001_77873391 0.12 FKSG61
9545
 0.11
chr1_167458663_167458959 0.12 CD247
 CD247 molecule
 28964
 0.16
chr1_235439552_235439703 0.12 GGPS1
 geranylgeranyl diphosphate synthase 1
 51038
 0.11
chr20_48955704_48955952 0.12 ENSG00000244376
 .
 90192
 0.08
chr9_92078215_92078535 0.12 SEMA4D
 sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D
 7507
 0.25
chr11_128479669_128479993 0.12 ETS1
 v-ets avian erythroblastosis virus E26 oncogene homolog 1
 22378
 0.2
chr2_207025046_207025348 0.11 EEF1B2
 eukaryotic translation elongation factor 1 beta 2
 866
 0.28
chr16_17461094_17461491 0.11 XYLT1
 xylosyltransferase I
 103446
 0.08
chr1_117269856_117270128 0.11 CD2
 CD2 molecule
 27015
 0.15
chr16_1013502_1013938 0.11 LMF1
 lipase maturation factor 1
 402
 0.77
chr3_58292293_58292444 0.11 RPP14
 ribonuclease P/MRP 14kDa subunit
 331
 0.89
chr20_61613987_61614138 0.11 BHLHE23
 basic helix-loop-helix family, member e23
 24325
 0.13
chr1_27941254_27941405 0.11 FGR
 feline Gardner-Rasheed sarcoma viral oncogene homolog
 9244
 0.14
chr5_111109748_111109899 0.11 NREP
 neuronal regeneration related protein
 15908
 0.22
chr7_142966484_142967056 0.11 GSTK1
 glutathione S-transferase kappa 1
 6221
 0.1
chr5_156695529_156695722 0.11 CYFIP2
 cytoplasmic FMR1 interacting protein 2
 737
 0.55
chr14_91855068_91855898 0.11 CCDC88C
 coiled-coil domain containing 88C
 28207
 0.19
chr2_114189862_114190032 0.11 CBWD2
 COBW domain containing 2
 5321
 0.16
chr20_8349732_8349927 0.11 PLCB1-IT1
 PLCB1 intronic transcript 1 (non-protein coding)
 120457
 0.06
chr6_147204276_147204427 0.11 STXBP5-AS1
 STXBP5 antisense RNA 1
 28391
 0.24
chr3_16971345_16971496 0.11 PLCL2
 phospholipase C-like 2
 3162
 0.28
chr9_133711275_133711489 0.11 ABL1
 c-abl oncogene 1, non-receptor tyrosine kinase
 929
 0.63
chr7_123387796_123388107 0.11 WASL
 Wiskott-Aldrich syndrome-like
 1170
 0.35
chr3_4951013_4951164 0.11 BHLHE40-AS1
 BHLHE40 antisense RNA 1
 2902
 0.27
chr9_135382524_135382903 0.11 BARHL1
 BarH-like homeobox 1
 74859
 0.09
chr20_47334105_47334366 0.11 ENSG00000251876
 .
 21750
 0.26
chr15_91912605_91912789 0.11 SV2B
 synaptic vesicle glycoprotein 2B
 143597
 0.05
chr12_54145980_54146199 0.10 CALCOCO1
 calcium binding and coiled-coil domain 1
 24560
 0.14
chr18_46654785_46654936 0.10 RP11-15F12.3
12189
 0.2
chr2_28848726_28848877 0.10 PLB1
 phospholipase B1
 4652
 0.23
chr20_3389002_3389295 0.10 C20orf194
 chromosome 20 open reading frame 194
 876
 0.52
chr5_150595265_150595488 0.10 GM2A
 GM2 ganglioside activator
 3665
 0.22
chr3_142347554_142347705 0.10 PLS1
 plastin 1
 5380
 0.18
chr16_75102873_75103024 0.10 ZNRF1
 zinc and ring finger 1, E3 ubiquitin protein ligase
 35734
 0.13
chr14_69366794_69366948 0.10 ACTN1
 actinin, alpha 1
 10012
 0.23
chr1_58790005_58790188 0.10 DAB1
 Dab, reelin signal transducer, homolog 1 (Drosophila)
 73885
 0.12
chr2_175533335_175533616 0.10 WIPF1
 WAS/WASL interacting protein family, member 1
 14124
 0.23
chr13_108979091_108979372 0.10 ENSG00000223177
 .
 25552
 0.22
chr3_18411245_18411586 0.10 RP11-158G18.1
39712
 0.18
chr16_80690009_80690168 0.10 ENSG00000265341
 .
 9372
 0.18
chr16_17376292_17376629 0.10 CTD-2576D5.4
148099
 0.05
chr16_23921554_23921705 0.10 PRKCB
 protein kinase C, beta
 73085
 0.11
chr22_40322800_40322970 0.10 GRAP2
 GRB2-related adaptor protein 2
 244
 0.92
chr5_164987815_164987966 0.10 ENSG00000252794
 .
 48556
 0.2
chr5_49726182_49726490 0.10 EMB
 embigin
 1775
 0.54
chr5_59892399_59892550 0.10 DEPDC1B
 DEP domain containing 1B
 103487
 0.07
chr17_1462563_1462714 0.10 PITPNA
 phosphatidylinositol transfer protein, alpha
 457
 0.74
chr14_95929937_95930315 0.10 SYNE3
 spectrin repeat containing, nuclear envelope family member 3
 7600
 0.21
chr16_81668859_81669010 0.10 CMIP
 c-Maf inducing protein
 10029
 0.29
chr10_50012073_50012379 0.10 WDFY4
 WDFY family member 4
 1443
 0.49
chr20_49001914_49002090 0.10 ENSG00000244376
 .
 44018
 0.16
chr1_156737883_156738034 0.10 PRCC
 papillary renal cell carcinoma (translocation-associated)
 612
 0.57
chr13_96421703_96421854 0.10 ENSG00000251901
 .
 54746
 0.15
chr9_70851374_70851561 0.10 CBWD3
 COBW domain containing 3
 4930
 0.19
chr16_46798396_46798547 0.10 MYLK3
 myosin light chain kinase 3
 1313
 0.49
chr3_168335883_168336034 0.10 ENSG00000207717
 .
 66316
 0.14
chr9_97089685_97089867 0.10 NUTM2F
 NUT family member 2F
 1150
 0.51
chr1_9685978_9686129 0.10 PIK3CD
 phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta
 25737
 0.14
chr15_69106923_69107111 0.10 ANP32A
 acidic (leucine-rich) nuclear phosphoprotein 32 family, member A
 6208
 0.23
chr4_143624938_143625093 0.10 INPP4B
 inositol polyphosphate-4-phosphatase, type II, 105kDa
 142428
 0.05
chr3_187717370_187717716 0.10 LPP
 LIM domain containing preferred translocation partner in lipoma
 153529
 0.04
chr2_102239938_102240253 0.10 MAP4K4
 mitogen-activated protein kinase kinase kinase kinase 4
 73217
 0.12
chr1_68697619_68697806 0.10 WLS
 wntless Wnt ligand secretion mediator
 251
 0.94
chr20_56482524_56482675 0.10 ENSG00000221007
 .
 11341
 0.21
chr17_4403592_4403861 0.10 AC118754.4
757
 0.49
chr3_186730308_186730463 0.10 ST6GAL1
 ST6 beta-galactosamide alpha-2,6-sialyltranferase 1
 9258
 0.24
chr3_128402800_128402979 0.10 RPN1
 ribophorin I
 2971
 0.26
chr14_81423199_81423350 0.10 TSHR
 thyroid stimulating hormone receptor
 1275
 0.49
chr11_111317717_111317915 0.10 RP11-794P6.3
2777
 0.15
chr19_55008845_55009031 0.10 LAIR2
 leukocyte-associated immunoglobulin-like receptor 2
 162
 0.91
chr10_29612226_29612377 0.10 LYZL1
 lysozyme-like 1
 34311
 0.21
chr7_142024322_142024543 0.10 PRSS3P3
 protease, serine, 3 pseudogene 3
 34823
 0.18
chr2_8615200_8615353 0.10 AC011747.7
200620
 0.03
chr7_28631139_28631290 0.09 CREB5
 cAMP responsive element binding protein 5
 17464
 0.3
chr5_79432109_79432283 0.09 CTC-458I2.2
8012
 0.23
chr6_16713160_16713355 0.09 RP1-151F17.1
48112
 0.16
chr12_1613825_1614060 0.09 WNT5B
 wingless-type MMTV integration site family, member 5B
 25115
 0.21
chr1_33115546_33115708 0.09 ZBTB8OS
 zinc finger and BTB domain containing 8 opposite strand
 534
 0.62
chr13_27867259_27867592 0.09 RASL11A
 RAS-like, family 11, member A
 22961
 0.11
chr2_69859573_69859724 0.09 AAK1
 AP2 associated kinase 1
 11138
 0.21
chr17_40574094_40574415 0.09 PTRF
 polymerase I and transcript release factor
 1281
 0.3
chr3_72357618_72357769 0.09 ENSG00000212070
 .
 46114
 0.19
chr14_59950418_59950569 0.09 L3HYPDH
 L-3-hydroxyproline dehydratase (trans-)
 90
 0.91
chr16_16193929_16194080 0.09 ABCC1
 ATP-binding cassette, sub-family C (CFTR/MRP), member 1
 90291
 0.07
chr16_29630080_29630315 0.09 ENSG00000266758
 .
 19611
 0.13
chr2_158768231_158768382 0.09 ENSG00000251980
 .
 978
 0.56
chr1_186268373_186268524 0.09 PRG4
 proteoglycan 4
 3037
 0.25
chr3_186745073_186745228 0.09 ST6GAL1
 ST6 beta-galactosamide alpha-2,6-sialyltranferase 1
 1879
 0.42
chr3_153535873_153536024 0.09 ENSG00000238755
 .
 55633
 0.16
chr17_76235442_76235593 0.09 TMEM235
 transmembrane protein 235
 7395
 0.14
chr8_133770079_133770329 0.09 TMEM71
 transmembrane protein 71
 2590
 0.28
chr12_68028301_68028534 0.09 DYRK2
 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 2
 13701
 0.26
chr5_145583999_145584318 0.09 RBM27
 RNA binding motif protein 27
 995
 0.56
chr1_200120948_200121380 0.09 ENSG00000221403
 .
 7202
 0.28
chr18_74182005_74182224 0.09 ZNF516
 zinc finger protein 516
 20621
 0.16
chr3_187840204_187840389 0.09 LPP
 LIM domain containing preferred translocation partner in lipoma
 30776
 0.18
chr7_139315604_139315856 0.09 HIPK2
 homeodomain interacting protein kinase 2
 106111
 0.06
chr2_225806667_225806962 0.09 DOCK10
 dedicator of cytokinesis 10
 4968
 0.33
chr8_49862673_49862887 0.09 SNAI2
 snail family zinc finger 2
 28481
 0.25
chr20_40221307_40221497 0.09 CHD6
 chromodomain helicase DNA binding protein 6
 22010
 0.23
chr18_5709587_5709738 0.09 ENSG00000252432
 .
 47613
 0.15
chr1_236284257_236284560 0.09 GPR137B
 G protein-coupled receptor 137B
 21424
 0.19
chr4_185201552_185201820 0.09 ENSG00000244512
 .
 1597
 0.41
chr10_98411356_98411597 0.09 PIK3AP1
 phosphoinositide-3-kinase adaptor protein 1
 17892
 0.19
chr8_80733314_80733465 0.09 ENSG00000238884
 .
 20959
 0.23
chr18_13260507_13260658 0.09 LDLRAD4
 low density lipoprotein receptor class A domain containing 4
 17520
 0.17
chr20_31261981_31262132 0.09 COMMD7
 COMM domain containing 7
 69156
 0.08
chr9_33154550_33154783 0.09 RP11-326F20.5
12307
 0.14
chr12_65108821_65108972 0.09 AC025262.1
 Mesenchymal stem cell protein DSC96; Uncharacterized protein
 18567
 0.13
chr5_98103966_98104240 0.09 RGMB
 repulsive guidance molecule family member b
 896
 0.64
chr2_89167006_89167157 0.09 IGKJ1
 immunoglobulin kappa joining 1
 5646
 0.09
chr1_174929832_174929983 0.09 RABGAP1L
 RAB GTPase activating protein 1-like
 3998
 0.18
chr7_135656817_135657003 0.09 MTPN
 myotrophin
 5154
 0.19
chr17_73381904_73382055 0.09 GRB2
 growth factor receptor-bound protein 2
 7758
 0.1
chr3_16384687_16384897 0.09 RP11-415F23.4
1841
 0.32
chr1_179801518_179801669 0.09 RP11-12M5.3
14267
 0.16
chr3_39330707_39330989 0.09 CX3CR1
 chemokine (C-X3-C motif) receptor 1
 7622
 0.2
chr10_64515756_64515907 0.09 ADO
 2-aminoethanethiol (cysteamine) dioxygenase
 48685
 0.13
chr11_110349538_110349689 0.09 FDX1
 ferredoxin 1
 49006
 0.18
chr21_26782848_26782999 0.09 ENSG00000238314
 .
 59590
 0.13
chr20_57828749_57828900 0.09 EDN3
 endothelin 3
 46658
 0.15
chr8_57126457_57126608 0.08 CHCHD7
 coiled-coil-helix-coiled-coil-helix domain containing 7
 455
 0.81
chr5_76696412_76696563 0.08 PDE8B
 phosphodiesterase 8B
 9762
 0.26
chr3_71862606_71862965 0.08 ENSG00000239250
 .
 13543
 0.2
chr16_54033588_54033739 0.08 RP11-357N13.2
218
 0.93
chr2_29593489_29593640 0.08 ENSG00000266310
 .
 133295
 0.05

Histogram of CRE-TSS distances for CREs targeted by :

Histogram of

Rank distribution of CRE target scores:

Histogram of target CRE score.

Distribution of target CREs across different genomic regions:

Weighted Piechart of Weighted Piechart of Weighted Piechart of

Network of associatons between targets according to the STRING database.

First level regulatory network of NKX1-1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0032632 interleukin-3 production(GO:0032632)
0.0 0.2 GO:0006610 ribosomal protein import into nucleus(GO:0006610)
0.0 0.1 GO:0033152 immunoglobulin V(D)J recombination(GO:0033152)
0.0 0.2 GO:0022027 interkinetic nuclear migration(GO:0022027)
0.0 0.1 GO:0006552 leucine catabolic process(GO:0006552)
0.0 0.1 GO:0006198 cAMP catabolic process(GO:0006198)
0.0 0.1 GO:0030854 positive regulation of granulocyte differentiation(GO:0030854)
0.0 0.1 GO:0031946 regulation of glucocorticoid biosynthetic process(GO:0031946)
0.0 0.1 GO:0045663 positive regulation of myoblast differentiation(GO:0045663)
0.0 0.1 GO:0001672 regulation of chromatin assembly or disassembly(GO:0001672)
0.0 0.0 GO:0042109 lymphotoxin A production(GO:0032641) lymphotoxin A biosynthetic process(GO:0042109)
0.0 0.0 GO:0019276 UDP-N-acetylgalactosamine metabolic process(GO:0019276)
0.0 0.0 GO:1900120 regulation of receptor binding(GO:1900120) negative regulation of receptor binding(GO:1900121)
0.0 0.1 GO:0055064 cellular chloride ion homeostasis(GO:0030644) chloride ion homeostasis(GO:0055064)
0.0 0.1 GO:0090400 stress-induced premature senescence(GO:0090400)
0.0 0.1 GO:0034086 maintenance of sister chromatid cohesion(GO:0034086) maintenance of mitotic sister chromatid cohesion(GO:0034088)
0.0 0.0 GO:0071224 cellular response to peptidoglycan(GO:0071224)
0.0 0.0 GO:0002328 pro-B cell differentiation(GO:0002328)
0.0 0.0 GO:0001865 NK T cell differentiation(GO:0001865) regulation of NK T cell differentiation(GO:0051136) positive regulation of NK T cell differentiation(GO:0051138)
0.0 0.1 GO:0001911 negative regulation of leukocyte mediated cytotoxicity(GO:0001911)
0.0 0.0 GO:0031580 membrane raft polarization(GO:0001766) membrane raft distribution(GO:0031580)
0.0 0.0 GO:0035455 response to interferon-alpha(GO:0035455)
0.0 0.0 GO:0009296 obsolete flagellum assembly(GO:0009296)
0.0 0.0 GO:0033314 mitotic DNA replication checkpoint(GO:0033314)
0.0 0.0 GO:0021542 dentate gyrus development(GO:0021542)
0.0 0.1 GO:0030206 chondroitin sulfate biosynthetic process(GO:0030206)
0.0 0.0 GO:0001992 regulation of systemic arterial blood pressure by vasopressin(GO:0001992)
0.0 0.1 GO:0006975 DNA damage induced protein phosphorylation(GO:0006975)
0.0 0.1 GO:0051299 centrosome separation(GO:0051299)
0.0 0.0 GO:0002693 positive regulation of cellular extravasation(GO:0002693)
0.0 0.0 GO:0010748 negative regulation of plasma membrane long-chain fatty acid transport(GO:0010748) negative regulation of anion transmembrane transport(GO:1903960) negative regulation of fatty acid transport(GO:2000192)
0.0 0.1 GO:0016540 protein autoprocessing(GO:0016540)
0.0 0.0 GO:0006551 leucine metabolic process(GO:0006551)
0.0 0.0 GO:0043951 negative regulation of cAMP-mediated signaling(GO:0043951)
0.0 0.1 GO:1901503 ether lipid biosynthetic process(GO:0008611) glycerol ether biosynthetic process(GO:0046504) ether biosynthetic process(GO:1901503)
0.0 0.0 GO:0046010 positive regulation of circadian sleep/wake cycle, non-REM sleep(GO:0046010)
0.0 0.1 GO:0046827 positive regulation of protein export from nucleus(GO:0046827)
0.0 0.0 GO:0006924 activation-induced cell death of T cells(GO:0006924)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)
0.0 0.0 GO:0070022 transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.0 0.1 GO:0000138 Golgi trans cisterna(GO:0000138)
0.0 0.1 GO:0042101 T cell receptor complex(GO:0042101)
0.0 0.0 GO:0032593 insulin-responsive compartment(GO:0032593)
0.0 0.1 GO:0071778 obsolete WINAC complex(GO:0071778)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0016149 translation release factor activity, codon specific(GO:0016149)
0.0 0.1 GO:0030375 thyroid hormone receptor coactivator activity(GO:0030375)
0.0 0.1 GO:0047756 chondroitin 4-sulfotransferase activity(GO:0047756)
0.0 0.1 GO:0008321 Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.0 0.1 GO:0004911 interleukin-2 receptor activity(GO:0004911)
0.0 0.1 GO:0047238 glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity(GO:0047238)
0.0 0.2 GO:0016493 C-C chemokine receptor activity(GO:0016493)
0.0 0.0 GO:0050253 retinyl-palmitate esterase activity(GO:0050253)
0.0 0.1 GO:0030284 estrogen receptor activity(GO:0030284)
0.0 0.2 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0 0.0 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.0 0.1 GO:0004904 interferon receptor activity(GO:0004904)
0.0 0.1 GO:0070087 chromo shadow domain binding(GO:0070087)
0.0 0.1 GO:0008526 phosphatidylinositol transporter activity(GO:0008526)
0.0 0.0 GO:0031705 bombesin receptor binding(GO:0031705) endothelin B receptor binding(GO:0031708)
0.0 0.0 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.0 0.0 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.0 0.0 GO:0000293 ferric-chelate reductase activity(GO:0000293)
0.0 0.0 GO:0042608 T cell receptor binding(GO:0042608)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 PID TCR JNK PATHWAY JNK signaling in the CD4+ TCR pathway
0.0 0.2 PID NFKAPPAB ATYPICAL PATHWAY Atypical NF-kappaB pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.0 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.0 0.0 REACTOME CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
0.0 0.1 REACTOME BINDING AND ENTRY OF HIV VIRION Genes involved in Binding and entry of HIV virion
0.0 0.4 REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.0 0.0 REACTOME G ALPHA S SIGNALLING EVENTS Genes involved in G alpha (s) signalling events