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ENCODE: H3K4me1 ChIP-Seq of primary human cells
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Results for NKX1-2_RAX

Z-value: 0.72

Motif logo

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Transcription factors associated with NKX1-2_RAX

Gene Symbol Gene ID Gene Info
NKX1-2
ENSG00000229544.6 NK1 homeobox 2
RAX
ENSG00000134438.9 retina and anterior neural fold homeobox

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE Gene Distance Association probability Pearson corr. coef. P-value Plot
chr10_126138239_126138552NKX1-21550.9420680.432.5e-01Click!
chr10_126137738_126137889NKX1-27370.5646330.333.8e-01Click!
chr10_126137330_126137616NKX1-210770.3717260.314.2e-01Click!
chr10_126138898_126139049NKX1-22200.9197420.215.9e-01Click!
chr10_126137966_126138119NKX1-25080.7254840.019.8e-01Click!
chr18_56938469_56938620RAX20730.349346-0.618.0e-02Click!
chr18_56935922_56936202RAX45550.2419040.521.5e-01Click!
chr18_56936662_56936813RAX38800.2543340.422.6e-01Click!
chr18_56939397_56939548RAX11450.5346130.402.9e-01Click!
chr18_56936206_56936357RAX43360.2453720.393.0e-01Click!

Activity of the NKX1-2_RAX motif across conditions

Conditions sorted by the z-value of the NKX1-2_RAX motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE) Target Score Top associated gene Gene Info Distance of CRE to TSS CRE/Gene association probability
chr6_117804732_117805043 0.41 DCBLD1
 discoidin, CUB and LCCL domain containing 1
 1062
 0.49
chr2_202077121_202077490 0.37 CASP8
 caspase 8, apoptosis-related cysteine peptidase
 20861
 0.15
chr6_25005285_25005494 0.36 ENSG00000244618
 .
 26121
 0.17
chr5_124214579_124214730 0.36 ZNF608
 zinc finger protein 608
 130154
 0.05
chr9_134852338_134852532 0.35 MED27
 mediator complex subunit 27
 102818
 0.07
chr17_72457353_72457898 0.34 CD300A
 CD300a molecule
 4930
 0.16
chr18_74872232_74872572 0.34 MBP
 myelin basic protein
 27602
 0.24
chr5_73534753_73534915 0.33 ENSG00000222551
 .
 32756
 0.22
chr9_123424941_123425186 0.33 MEGF9
 multiple EGF-like-domains 9
 51549
 0.15
chr1_87082986_87083335 0.32 ENSG00000221702
 .
 11120
 0.18
chr14_75795544_75795840 0.32 FOS
 FBJ murine osteosarcoma viral oncogene homolog
 48796
 0.11
chr2_160789612_160789827 0.31 LY75-CD302
 LY75-CD302 readthrough
 28498
 0.19
chr4_140724600_140724880 0.31 ENSG00000252233
 .
 9153
 0.26
chr12_1725180_1725331 0.31 WNT5B
 wingless-type MMTV integration site family, member 5B
 967
 0.58
chr3_187491464_187491692 0.30 BCL6
 B-cell CLL/lymphoma 6
 28063
 0.2
chr2_64814973_64815124 0.29 ENSG00000252414
 .
 9022
 0.22
chr1_175157741_175158025 0.29 KIAA0040
 KIAA0040
 4007
 0.31
chr3_112193935_112194086 0.28 BTLA
 B and T lymphocyte associated
 24195
 0.21
chr13_41548373_41548524 0.28 ELF1
 E74-like factor 1 (ets domain transcription factor)
 7970
 0.2
chr2_68650725_68651008 0.28 FBXO48
 F-box protein 48
 43524
 0.12
chr18_13124723_13124874 0.28 RP11-794M8.1
91526
 0.07
chr10_11155205_11156000 0.28 CELF2-AS2
 CELF2 antisense RNA 2
 15166
 0.21
chr14_92973076_92973375 0.27 RIN3
 Ras and Rab interactor 3
 6893
 0.29
chr4_14996539_14996690 0.27 CPEB2
 cytoplasmic polyadenylation element binding protein 2
 7684
 0.31
chr8_142160611_142160762 0.27 DENND3
 DENN/MADD domain containing 3
 9384
 0.2
chr7_139555811_139556201 0.26 TBXAS1
 thromboxane A synthase 1 (platelet)
 26896
 0.22
chr2_202861641_202861792 0.26 FZD7
 frizzled family receptor 7
 37594
 0.13
chr1_89949288_89949439 0.26 LRRC8B
 leucine rich repeat containing 8 family, member B
 41032
 0.16
chr4_153608932_153609083 0.26 TMEM154
 transmembrane protein 154
 7690
 0.22
chr10_21807059_21807447 0.26 SKIDA1
 SKI/DACH domain containing 1
 405
 0.78
chr15_92455349_92455602 0.25 SLCO3A1
 solute carrier organic anion transporter family, member 3A1
 58124
 0.15
chr8_27223358_27224128 0.25 PTK2B
 protein tyrosine kinase 2 beta
 14425
 0.22
chr14_103586056_103586207 0.25 TNFAIP2
 tumor necrosis factor, alpha-induced protein 2
 3667
 0.2
chr2_153267355_153267720 0.25 FMNL2
 formin-like 2
 75786
 0.12
chr18_61561537_61561693 0.25 SERPINB10
 serpin peptidase inhibitor, clade B (ovalbumin), member 10
 2793
 0.24
chr5_55443907_55444286 0.25 ENSG00000223003
 .
 1423
 0.42
chr5_59527719_59528015 0.25 PDE4D
 phosphodiesterase 4D, cAMP-specific
 46442
 0.18
chr4_108721534_108721685 0.25 SGMS2
 sphingomyelin synthase 2
 24110
 0.21
chr14_70110903_70111120 0.25 KIAA0247
 KIAA0247
 32698
 0.18
chr1_200120948_200121380 0.25 ENSG00000221403
 .
 7202
 0.28
chr2_225451534_225451729 0.24 CUL3
 cullin 3
 1521
 0.57
chr5_17413551_17413702 0.24 ENSG00000201715
 .
 67901
 0.13
chr7_102072492_102072712 0.24 ORAI2
 ORAI calcium release-activated calcium modulator 2
 951
 0.34
chr1_246233834_246234131 0.24 RP11-83A16.1
37129
 0.17
chr22_27836384_27836535 0.24 RP11-375H17.1
276009
 0.01
chr7_80742262_80742413 0.24 AC005008.2
 Uncharacterized protein
 62487
 0.16
chr1_90290727_90290878 0.24 LRRC8D
 leucine rich repeat containing 8 family, member D
 3322
 0.28
chr17_40207202_40207353 0.24 ZNF385C
 zinc finger protein 385C
 7798
 0.1
chr3_142347554_142347705 0.23 PLS1
 plastin 1
 5380
 0.18
chr10_74579021_74579203 0.23 RP11-354E23.5
52794
 0.12
chr8_48296668_48296819 0.23 SPIDR
 scaffolding protein involved in DNA repair
 56220
 0.16
chrX_39003232_39003473 0.23 ENSG00000207122
 .
 62814
 0.16
chr17_8311463_8311614 0.23 NDEL1
 nudE neurodevelopment protein 1-like 1
 4911
 0.12
chr4_130543160_130543402 0.23 ENSG00000222861
 .
 238374
 0.02
chr8_130559417_130559631 0.23 ENSG00000266387
 .
 49611
 0.09
chr16_73092870_73093114 0.23 ZFHX3
 zinc finger homeobox 3
 605
 0.79
chr5_36842497_36842706 0.22 NIPBL
 Nipped-B homolog (Drosophila)
 34260
 0.23
chr1_245120739_245120890 0.22 ENSG00000252073
 .
 2654
 0.2
chr20_1550565_1550716 0.22 SIRPB1
 signal-regulatory protein beta 1
 1918
 0.25
chr4_26729613_26729764 0.22 ENSG00000200999
 .
 25757
 0.23
chr3_121990121_121990409 0.22 ENSG00000221474
 .
 10435
 0.16
chr20_18487226_18487377 0.22 SEC23B
 Sec23 homolog B (S. cerevisiae)
 836
 0.5
chr21_48025165_48025458 0.22 S100B
 S100 calcium binding protein B
 190
 0.95
chr2_45490582_45490733 0.22 SIX2
 SIX homeobox 2
 254088
 0.02
chr12_10282940_10283100 0.22 CLEC7A
 C-type lectin domain family 7, member A
 164
 0.93
chr16_4674083_4674234 0.22 MGRN1
 mahogunin ring finger 1, E3 ubiquitin protein ligase
 633
 0.59
chr10_45559099_45559250 0.22 RSU1P2
 Ras suppressor protein 1 pseudogene 2
 52375
 0.1
chr12_55435891_55436042 0.22 NEUROD4
 neuronal differentiation 4
 22237
 0.2
chr16_50720309_50720716 0.22 SNX20
 sorting nexin 20
 5248
 0.13
chr12_25208694_25208845 0.22 LRMP
 lymphoid-restricted membrane protein
 3095
 0.27
chr15_93372987_93373270 0.22 FAM174B
 family with sequence similarity 174, member B
 20100
 0.15
chr2_8038740_8038891 0.22 ENSG00000221255
 .
 321843
 0.01
chr18_19178052_19178356 0.21 ESCO1
 establishment of sister chromatid cohesion N-acetyltransferase 1
 2493
 0.23
chr16_17376292_17376629 0.21 CTD-2576D5.4
148099
 0.05
chr5_75600048_75600202 0.21 RP11-466P24.6
7162
 0.3
chr8_56885039_56885250 0.21 ENSG00000240905
 .
 7952
 0.16
chr1_169663386_169663580 0.21 SELL
 selectin L
 17356
 0.18
chr1_169571123_169571274 0.21 F5
 coagulation factor V (proaccelerin, labile factor)
 15372
 0.19
chr5_75688534_75688866 0.21 IQGAP2
 IQ motif containing GTPase activating protein 2
 10374
 0.28
chr7_28712663_28712814 0.21 CREB5
 cAMP responsive element binding protein 5
 12860
 0.31
chr7_69119865_69120016 0.21 AUTS2
 autism susceptibility candidate 2
 55343
 0.16
chr4_101813891_101814042 0.21 EMCN-IT1
 EMCN intronic transcript 1 (non-protein coding)
 78529
 0.11
chr11_60250640_60250791 0.21 MS4A12
 membrane-spanning 4-domains, subfamily A, member 12
 9536
 0.16
chr2_172008488_172008813 0.21 ENSG00000238567
 .
 5810
 0.25
chr10_7299593_7299834 0.21 SFMBT2
 Scm-like with four mbt domains 2
 150994
 0.04
chr9_92032244_92032395 0.21 SEMA4D
 sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D
 1429
 0.51
chr15_94796190_94796879 0.21 MCTP2
 multiple C2 domains, transmembrane 2
 21767
 0.29
chr20_61070311_61070462 0.21 GATA5
 GATA binding protein 5
 19360
 0.15
chr4_157891332_157891565 0.21 PDGFC
 platelet derived growth factor C
 607
 0.78
chr21_16064096_16064532 0.20 AF165138.7
 Protein LOC388813
 33172
 0.21
chr11_9715214_9715365 0.20 ENSG00000201564
 .
 12818
 0.18
chr15_101790476_101790819 0.20 CHSY1
 chondroitin sulfate synthase 1
 1490
 0.37
chr4_36305674_36305831 0.20 DTHD1
 death domain containing 1
 20108
 0.21
chr15_48251538_48251689 0.20 SLC24A5
 solute carrier family 24 (sodium/potassium/calcium exchanger), member 5
 161556
 0.03
chr3_128402800_128402979 0.20 RPN1
 ribophorin I
 2971
 0.26
chr2_222385882_222386088 0.20 ENSG00000221432
 .
 1608
 0.44
chr7_133563283_133563434 0.20 EXOC4
 exocyst complex component 4
 51864
 0.19
chr6_91584945_91585096 0.20 MAP3K7
 mitogen-activated protein kinase kinase kinase 7
 288256
 0.01
chr1_9741200_9741351 0.20 RP11-558F24.4
6338
 0.18
chr9_137251018_137251277 0.20 ENSG00000263897
 .
 20110
 0.22
chr3_14467854_14468179 0.20 SLC6A6
 solute carrier family 6 (neurotransmitter transporter), member 6
 6162
 0.25
chr10_14584774_14585305 0.20 FAM107B
 family with sequence similarity 107, member B
 5630
 0.27
chr8_96160918_96161069 0.20 PLEKHF2
 pleckstrin homology domain containing, family F (with FYVE domain) member 2
 14689
 0.21
chr14_70168130_70168306 0.20 SRSF5
 serine/arginine-rich splicing factor 5
 25399
 0.21
chr2_175207474_175207756 0.20 AC018470.1
 Uncharacterized protein FLJ46347
 5464
 0.18
chr3_194601465_194601616 0.20 FAM43A
 family with sequence similarity 43, member A
 194918
 0.02
chr7_80219632_80219783 0.20 CD36
 CD36 molecule (thrombospondin receptor)
 11759
 0.29
chr5_59558878_59559029 0.20 ENSG00000202017
 .
 41025
 0.2
chr17_63043618_63043821 0.20 RP11-583F2.5
4308
 0.21
chr2_169927871_169928022 0.20 DHRS9
 dehydrogenase/reductase (SDR family) member 9
 1064
 0.56
chr7_41527568_41527719 0.20 INHBA-AS1
 INHBA antisense RNA 1
 205871
 0.03
chr2_176418395_176418546 0.20 ENSG00000221347
 .
 223369
 0.02
chr2_163263039_163263190 0.20 GCA
 grancalcin, EF-hand calcium binding protein
 50166
 0.15
chr7_16818603_16818754 0.20 AC073333.1
 Uncharacterized protein
 10188
 0.17
chr17_72033410_72033561 0.19 RPL38
 ribosomal protein L38
 166236
 0.03
chr14_72064329_72064928 0.19 SIPA1L1
 signal-induced proliferation-associated 1 like 1
 323
 0.94
chr16_28942567_28942718 0.19 CD19
 CD19 molecule
 618
 0.49
chr2_8007405_8007668 0.19 ENSG00000221255
 .
 290564
 0.01
chr8_134075895_134076274 0.19 SLA
 Src-like-adaptor
 3481
 0.31
chr8_80873858_80874009 0.19 RP11-26J3.3
4317
 0.28
chr6_54888900_54889051 0.19 RP3-523K23.2
81010
 0.11
chr2_26634709_26634860 0.19 DRC1
 dynein regulatory complex subunit 1 homolog (Chlamydomonas)
 10000
 0.21
chr6_17700032_17700183 0.19 RP11-500C11.3
6381
 0.17
chrX_147584575_147584726 0.19 AFF2
 AF4/FMR2 family, member 2
 2121
 0.31
chr3_37010622_37010773 0.19 ENSG00000210181
 .
 890
 0.56
chr12_104940888_104941108 0.19 CHST11
 carbohydrate (chondroitin 4) sulfotransferase 11
 41628
 0.17
chr8_19552777_19552928 0.19 CSGALNACT1
 chondroitin sulfate N-acetylgalactosaminyltransferase 1
 12580
 0.3
chr4_38663643_38663794 0.19 KLF3
 Kruppel-like factor 3 (basic)
 2099
 0.25
chr18_3790975_3791126 0.19 RP11-874J12.3
19620
 0.17
chr6_144171782_144171933 0.19 LTV1
 LTV1 homolog (S. cerevisiae)
 7376
 0.24
chr12_121548159_121548376 0.19 ENSG00000201945
 .
 3421
 0.22
chr8_56446230_56446381 0.18 RP11-628E19.2
12769
 0.28
chr10_94452668_94452819 0.18 HHEX
 hematopoietically expressed homeobox
 1131
 0.51
chr4_124341560_124341711 0.18 SPRY1
 sprouty homolog 1, antagonist of FGF signaling (Drosophila)
 20512
 0.29
chr22_17956676_17956827 0.18 CECR2
 cat eye syndrome chromosome region, candidate 2
 124
 0.97
chr1_117056573_117057331 0.18 CD58
 CD58 molecule
 30260
 0.14
chr3_177443249_177443545 0.18 ENSG00000200288
 .
 101200
 0.08
chr11_127376331_127376497 0.18 ENSG00000223315
 .
 98668
 0.08
chr1_233218809_233218980 0.18 PCNXL2
 pecanex-like 2 (Drosophila)
 24630
 0.26
chr13_32523758_32523999 0.18 EEF1DP3
 eukaryotic translation elongation factor 1 delta pseudogene 3
 2839
 0.36
chr5_140934914_140935065 0.18 CTD-2024I7.13
2889
 0.17
chr10_131583616_131583767 0.18 EBF3
 early B-cell factor 3
 56744
 0.14
chr1_172442879_172443090 0.18 C1orf105
 chromosome 1 open reading frame 105
 20951
 0.18
chr6_24523019_24523170 0.18 ALDH5A1
 aldehyde dehydrogenase 5 family, member A1
 27897
 0.17
chr2_122458404_122458555 0.18 ENSG00000238341
 .
 5154
 0.2
chr4_74945123_74945274 0.18 CXCL2
 chemokine (C-X-C motif) ligand 2
 19812
 0.13
chr6_35002148_35002432 0.18 TCP11
 t-complex 11, testis-specific
 86532
 0.08
chr5_64919668_64919819 0.18 TRIM23
 tripartite motif containing 23
 380
 0.59
chr12_82343405_82343568 0.18 PPFIA2
 protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 2
 190154
 0.03
chr10_76625035_76625298 0.18 KAT6B
 K(lysine) acetyltransferase 6B
 26708
 0.24
chr1_212325573_212325724 0.18 ENSG00000252879
 .
 52630
 0.12
chr12_115941638_115941789 0.18 RP11-116D17.1
 HCG2038717; Uncharacterized protein
 140896
 0.05
chr4_89526439_89526704 0.18 HERC3
 HECT and RLD domain containing E3 ubiquitin protein ligase 3
 374
 0.86
chr17_55827874_55828025 0.18 CCDC182
 coiled-coil domain containing 182
 5276
 0.22
chr16_3146077_3146254 0.18 ZSCAN10
 zinc finger and SCAN domain containing 10
 3064
 0.09
chr12_54150663_54151040 0.18 CALCOCO1
 calcium binding and coiled-coil domain 1
 29322
 0.13
chr6_47207680_47207905 0.18 TNFRSF21
 tumor necrosis factor receptor superfamily, member 21
 69849
 0.13
chr4_75466339_75466608 0.18 RP11-727M10.2
9499
 0.2
chr19_37288631_37289102 0.18 CTD-2162K18.5
401
 0.8
chr15_78462261_78462412 0.18 IDH3A
 isocitrate dehydrogenase 3 (NAD+) alpha
 6278
 0.16
chr1_226084453_226084634 0.18 LEFTY1
 left-right determination factor 1
 7697
 0.12
chr4_75296529_75296796 0.18 RP11-727M10.1
9512
 0.2
chr1_99337480_99337815 0.18 RP5-896L10.1
132185
 0.05
chr10_121459914_121460065 0.18 INPP5F
 inositol polyphosphate-5-phosphatase F
 25620
 0.18
chr14_70111444_70111741 0.18 KIAA0247
 KIAA0247
 33279
 0.18
chr12_64798932_64799366 0.18 XPOT
 exportin, tRNA
 323
 0.88
chrX_20456293_20456479 0.18 ENSG00000252978
 .
 13840
 0.3
chr10_77695413_77695615 0.18 ENSG00000215921
 .
 111978
 0.06
chr15_83733229_83733380 0.17 BTBD1
 BTB (POZ) domain containing 1
 2599
 0.17
chr10_131555094_131555311 0.17 RP11-109A6.2
55381
 0.15
chr13_99718141_99718440 0.17 DOCK9
 dedicator of cytokinesis 9
 20370
 0.18
chrX_119739145_119739532 0.17 MCTS1
 malignant T cell amplified sequence 1
 1162
 0.48
chr14_78120000_78120151 0.17 SPTLC2
 serine palmitoyltransferase, long chain base subunit 2
 36959
 0.13
chr2_112368076_112368227 0.17 ENSG00000266063
 .
 160560
 0.04
chr6_51167339_51167725 0.17 ENSG00000212532
 .
 161956
 0.04
chr16_10847383_10847602 0.17 NUBP1
 nucleotide binding protein 1
 4238
 0.21
chr11_77223581_77223900 0.17 PAK1
 p21 protein (Cdc42/Rac)-activated kinase 1
 38060
 0.13
chr10_72746069_72746220 0.17 PCBD1
 pterin-4 alpha-carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha
 97603
 0.07
chr17_47825562_47826034 0.17 FAM117A
 family with sequence similarity 117, member A
 15695
 0.14
chr9_92078215_92078535 0.17 SEMA4D
 sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D
 7507
 0.25
chr4_38602670_38602821 0.17 RP11-617D20.1
23451
 0.2
chr16_79651353_79651504 0.17 MAF
 v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog
 16817
 0.26
chr12_65369994_65370192 0.17 ENSG00000221564
 .
 37290
 0.18
chr3_169897682_169897967 0.17 PHC3
 polyhomeotic homolog 3 (Drosophila)
 1692
 0.35
chr2_8469788_8469939 0.17 AC011747.7
346033
 0.01
chr2_27273137_27273288 0.17 AGBL5-AS1
 AGBL5 antisense RNA 1
 80
 0.87
chr14_69196211_69196400 0.17 ENSG00000207089
 .
 6440
 0.23
chr12_4326122_4326423 0.17 CCND2
 cyclin D2
 56666
 0.11
chr14_81769226_81769438 0.17 STON2
 stonin 2
 26055
 0.23
chr1_9301737_9301925 0.17 H6PD
 hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase)
 1928
 0.34
chr5_57841537_57841688 0.17 CTD-2117L12.1
 Uncharacterized protein
 12458
 0.18
chr1_27156953_27157104 0.17 ZDHHC18
 zinc finger, DHHC-type containing 18
 1467
 0.28
chr6_37241298_37241494 0.17 TBC1D22B
 TBC1 domain family, member 22B
 15848
 0.15
chr2_43373091_43373242 0.17 ENSG00000207087
 .
 54534
 0.14
chr11_118097693_118098499 0.17 AMICA1
 adhesion molecule, interacts with CXADR antigen 1
 2287
 0.23
chr12_52096666_52096923 0.17 SCN8A
 sodium channel, voltage gated, type VIII, alpha subunit
 16587
 0.24
chr9_71643128_71643290 0.17 FXN
 frataxin
 6966
 0.23
chr5_148127360_148127525 0.16 ADRB2
 adrenoceptor beta 2, surface
 78714
 0.09
chr2_64863847_64864192 0.16 SERTAD2
 SERTA domain containing 2
 17028
 0.22
chr18_10787891_10788042 0.16 PIEZO2
 piezo-type mechanosensitive ion channel component 2
 826
 0.73

Histogram of CRE-TSS distances for CREs targeted by :

Histogram of

Rank distribution of CRE target scores:

Histogram of target CRE score.

Distribution of target CREs across different genomic regions:

Weighted Piechart of Weighted Piechart of Weighted Piechart of

Network of associatons between targets according to the STRING database.

First level regulatory network of NKX1-2_RAX

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0009756 carbohydrate mediated signaling(GO:0009756)
0.1 0.1 GO:0071481 cellular response to X-ray(GO:0071481)
0.1 0.2 GO:0001672 regulation of chromatin assembly or disassembly(GO:0001672)
0.1 0.2 GO:0060028 convergent extension involved in axis elongation(GO:0060028)
0.0 0.1 GO:0001831 trophectodermal cellular morphogenesis(GO:0001831)
0.0 0.2 GO:0060539 diaphragm development(GO:0060539)
0.0 0.1 GO:0010572 positive regulation of platelet activation(GO:0010572)
0.0 0.2 GO:0043951 negative regulation of cAMP-mediated signaling(GO:0043951)
0.0 0.2 GO:0030854 positive regulation of granulocyte differentiation(GO:0030854)
0.0 0.1 GO:0030948 negative regulation of vascular endothelial growth factor receptor signaling pathway(GO:0030948)
0.0 0.1 GO:0002513 tolerance induction to self antigen(GO:0002513)
0.0 0.1 GO:0001821 histamine secretion(GO:0001821)
0.0 0.1 GO:0016102 retinoic acid biosynthetic process(GO:0002138) diterpenoid biosynthetic process(GO:0016102)
0.0 0.1 GO:0006667 sphinganine metabolic process(GO:0006667)
0.0 0.1 GO:0045425 positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process(GO:0045425)
0.0 0.2 GO:0045714 regulation of low-density lipoprotein particle receptor biosynthetic process(GO:0045714)
0.0 0.1 GO:0071569 protein ufmylation(GO:0071569)
0.0 0.1 GO:0032020 ISG15-protein conjugation(GO:0032020)
0.0 0.0 GO:0034135 regulation of toll-like receptor 2 signaling pathway(GO:0034135)
0.0 0.1 GO:0032230 positive regulation of synaptic transmission, GABAergic(GO:0032230)
0.0 0.0 GO:0033689 negative regulation of osteoblast proliferation(GO:0033689)
0.0 0.1 GO:0046607 positive regulation of centrosome cycle(GO:0046607)
0.0 0.1 GO:0019987 obsolete negative regulation of anti-apoptosis(GO:0019987)
0.0 0.1 GO:0046398 UDP-glucuronate metabolic process(GO:0046398)
0.0 0.0 GO:0006659 phosphatidylserine biosynthetic process(GO:0006659)
0.0 0.1 GO:0002634 regulation of germinal center formation(GO:0002634)
0.0 0.1 GO:0031297 replication fork processing(GO:0031297)
0.0 0.0 GO:0048742 regulation of skeletal muscle fiber development(GO:0048742)
0.0 0.0 GO:0034139 regulation of toll-like receptor 3 signaling pathway(GO:0034139)
0.0 0.1 GO:0010956 negative regulation of calcidiol 1-monooxygenase activity(GO:0010956) negative regulation of vitamin D biosynthetic process(GO:0010957) negative regulation of vitamin metabolic process(GO:0046137)
0.0 0.4 GO:0046834 lipid phosphorylation(GO:0046834)
0.0 0.2 GO:0070373 negative regulation of ERK1 and ERK2 cascade(GO:0070373)
0.0 0.1 GO:0001661 conditioned taste aversion(GO:0001661)
0.0 0.1 GO:0014826 vein smooth muscle contraction(GO:0014826)
0.0 0.1 GO:0090281 negative regulation of calcium ion import(GO:0090281)
0.0 0.0 GO:0072216 positive regulation of metanephros development(GO:0072216)
0.0 0.1 GO:0060999 positive regulation of dendritic spine development(GO:0060999)
0.0 0.0 GO:0048478 replication fork protection(GO:0048478)
0.0 0.0 GO:0034086 maintenance of sister chromatid cohesion(GO:0034086) maintenance of mitotic sister chromatid cohesion(GO:0034088)
0.0 0.1 GO:0034421 post-translational protein acetylation(GO:0034421)
0.0 0.1 GO:0032007 negative regulation of TOR signaling(GO:0032007)
0.0 0.1 GO:0045663 positive regulation of myoblast differentiation(GO:0045663)
0.0 0.2 GO:0015671 oxygen transport(GO:0015671)
0.0 0.2 GO:0021527 spinal cord association neuron differentiation(GO:0021527)
0.0 0.1 GO:0051770 positive regulation of nitric-oxide synthase biosynthetic process(GO:0051770)
0.0 0.1 GO:0006703 estrogen biosynthetic process(GO:0006703)
0.0 0.1 GO:0032790 ribosome disassembly(GO:0032790)
0.0 0.0 GO:0002691 regulation of cellular extravasation(GO:0002691) positive regulation of cellular extravasation(GO:0002693)
0.0 0.1 GO:0032493 response to bacterial lipoprotein(GO:0032493) response to bacterial lipopeptide(GO:0070339) cellular response to bacterial lipoprotein(GO:0071220) cellular response to bacterial lipopeptide(GO:0071221)
0.0 0.2 GO:0030889 negative regulation of B cell proliferation(GO:0030889)
0.0 0.1 GO:0045292 mRNA cis splicing, via spliceosome(GO:0045292)
0.0 0.1 GO:0060528 secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development(GO:0060528)
0.0 0.2 GO:0001556 oocyte maturation(GO:0001556)
0.0 0.0 GO:0010193 response to ozone(GO:0010193)
0.0 0.1 GO:0006189 'de novo' IMP biosynthetic process(GO:0006189)
0.0 0.1 GO:0002025 vasodilation by norepinephrine-epinephrine involved in regulation of systemic arterial blood pressure(GO:0002025)
0.0 0.0 GO:0043374 CD8-positive, alpha-beta T cell activation(GO:0036037) CD8-positive, alpha-beta T cell differentiation(GO:0043374)
0.0 0.1 GO:0015917 aminophospholipid transport(GO:0015917)
0.0 0.1 GO:0060164 regulation of timing of neuron differentiation(GO:0060164)
0.0 0.1 GO:0002523 leukocyte migration involved in inflammatory response(GO:0002523)
0.0 0.1 GO:0019441 tryptophan catabolic process to kynurenine(GO:0019441)
0.0 0.1 GO:0032836 glomerular basement membrane development(GO:0032836)
0.0 0.0 GO:0071043 CUT catabolic process(GO:0071034) CUT metabolic process(GO:0071043)
0.0 0.1 GO:0045354 interferon-alpha biosynthetic process(GO:0045349) regulation of interferon-alpha biosynthetic process(GO:0045354) positive regulation of interferon-alpha biosynthetic process(GO:0045356)
0.0 0.0 GO:2000095 regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000095)
0.0 0.1 GO:0060017 parathyroid gland development(GO:0060017)
0.0 0.3 GO:0050853 B cell receptor signaling pathway(GO:0050853)
0.0 0.0 GO:0051451 myoblast migration(GO:0051451)
0.0 0.1 GO:0006654 phosphatidic acid biosynthetic process(GO:0006654)
0.0 0.1 GO:0071360 cellular response to exogenous dsRNA(GO:0071360)
0.0 0.0 GO:0046931 pore complex assembly(GO:0046931)
0.0 0.1 GO:0015937 coenzyme A biosynthetic process(GO:0015937)
0.0 0.1 GO:0000389 mRNA 3'-splice site recognition(GO:0000389)
0.0 0.1 GO:0022027 interkinetic nuclear migration(GO:0022027)
0.0 0.0 GO:2000542 negative regulation of gastrulation(GO:2000542)
0.0 0.1 GO:0072531 pyrimidine-containing compound transmembrane transport(GO:0072531)
0.0 0.1 GO:0050858 negative regulation of antigen receptor-mediated signaling pathway(GO:0050858) negative regulation of T cell receptor signaling pathway(GO:0050860)
0.0 0.0 GO:0045603 positive regulation of endothelial cell differentiation(GO:0045603)
0.0 0.0 GO:0009448 gamma-aminobutyric acid metabolic process(GO:0009448)
0.0 0.1 GO:0042989 sequestering of actin monomers(GO:0042989)
0.0 0.1 GO:0046835 carbohydrate phosphorylation(GO:0046835)
0.0 0.0 GO:0071436 sodium ion export(GO:0071436)
0.0 0.0 GO:0010966 regulation of phosphate transport(GO:0010966)
0.0 0.0 GO:0060084 synaptic transmission involved in micturition(GO:0060084)
0.0 0.1 GO:0006564 L-serine biosynthetic process(GO:0006564)
0.0 0.0 GO:0007352 zygotic specification of dorsal/ventral axis(GO:0007352)
0.0 0.0 GO:0061030 epithelial cell differentiation involved in mammary gland alveolus development(GO:0061030)
0.0 0.0 GO:0001878 response to yeast(GO:0001878)
0.0 0.0 GO:0045162 clustering of voltage-gated sodium channels(GO:0045162)
0.0 0.1 GO:0003351 epithelial cilium movement(GO:0003351) epithelial cilium movement involved in determination of left/right asymmetry(GO:0060287)
0.0 0.1 GO:0060158 phospholipase C-activating dopamine receptor signaling pathway(GO:0060158)
0.0 0.0 GO:0051151 negative regulation of smooth muscle cell differentiation(GO:0051151)
0.0 0.1 GO:2001259 activation of store-operated calcium channel activity(GO:0032237) positive regulation of calcium ion transmembrane transporter activity(GO:1901021) regulation of store-operated calcium channel activity(GO:1901339) positive regulation of store-operated calcium channel activity(GO:1901341) positive regulation of cation channel activity(GO:2001259)
0.0 0.0 GO:0070682 proteasome regulatory particle assembly(GO:0070682)
0.0 0.0 GO:0002669 lymphocyte anergy(GO:0002249) T cell tolerance induction(GO:0002517) regulation of T cell tolerance induction(GO:0002664) positive regulation of T cell tolerance induction(GO:0002666) regulation of T cell anergy(GO:0002667) positive regulation of T cell anergy(GO:0002669) T cell anergy(GO:0002870) regulation of lymphocyte anergy(GO:0002911) positive regulation of lymphocyte anergy(GO:0002913)
0.0 0.1 GO:0006975 DNA damage induced protein phosphorylation(GO:0006975)
0.0 0.0 GO:1901419 regulation of response to alcohol(GO:1901419)
0.0 0.1 GO:0045793 positive regulation of cell size(GO:0045793)
0.0 0.0 GO:0032497 detection of lipopolysaccharide(GO:0032497)
0.0 0.1 GO:0048488 synaptic vesicle recycling(GO:0036465) synaptic vesicle endocytosis(GO:0048488) clathrin-mediated endocytosis(GO:0072583)
0.0 0.0 GO:0043653 mitochondrial fragmentation involved in apoptotic process(GO:0043653)
0.0 0.0 GO:0019372 lipoxygenase pathway(GO:0019372)
0.0 0.1 GO:0007256 activation of JNKK activity(GO:0007256)
0.0 0.0 GO:0048496 maintenance of organ identity(GO:0048496)
0.0 0.0 GO:0033147 negative regulation of intracellular estrogen receptor signaling pathway(GO:0033147)
0.0 0.0 GO:0070295 renal water absorption(GO:0070295)
0.0 0.0 GO:0042723 thiamine metabolic process(GO:0006772) thiamine-containing compound metabolic process(GO:0042723)
0.0 0.2 GO:0090659 adult walking behavior(GO:0007628) walking behavior(GO:0090659)
0.0 0.1 GO:0043353 enucleate erythrocyte differentiation(GO:0043353)
0.0 0.0 GO:0032927 positive regulation of activin receptor signaling pathway(GO:0032927)
0.0 0.0 GO:0090195 chemokine secretion(GO:0090195) regulation of chemokine secretion(GO:0090196) positive regulation of chemokine secretion(GO:0090197)
0.0 0.0 GO:0060535 trachea cartilage morphogenesis(GO:0060535) cartilage morphogenesis(GO:0060536)
0.0 0.0 GO:0006686 sphingomyelin biosynthetic process(GO:0006686)
0.0 0.0 GO:0030388 fructose 1,6-bisphosphate metabolic process(GO:0030388)
0.0 0.1 GO:0007158 neuron cell-cell adhesion(GO:0007158)
0.0 0.1 GO:0070536 protein K63-linked deubiquitination(GO:0070536)
0.0 0.1 GO:0010823 negative regulation of mitochondrion organization(GO:0010823) negative regulation of release of cytochrome c from mitochondria(GO:0090201) negative regulation of apoptotic signaling pathway(GO:2001234)
0.0 0.0 GO:0007181 transforming growth factor beta receptor complex assembly(GO:0007181)
0.0 0.0 GO:0002643 regulation of tolerance induction(GO:0002643) positive regulation of tolerance induction(GO:0002645)
0.0 0.0 GO:0034625 fatty acid elongation, monounsaturated fatty acid(GO:0034625)
0.0 0.0 GO:0032898 neurotrophin production(GO:0032898)
0.0 0.1 GO:0006613 cotranslational protein targeting to membrane(GO:0006613)
0.0 0.1 GO:0000301 retrograde transport, vesicle recycling within Golgi(GO:0000301)
0.0 0.2 GO:0034199 activation of protein kinase A activity(GO:0034199)
0.0 0.0 GO:0008215 spermine metabolic process(GO:0008215)
0.0 0.1 GO:0008653 lipopolysaccharide metabolic process(GO:0008653)
0.0 0.0 GO:0009296 obsolete flagellum assembly(GO:0009296)
0.0 0.0 GO:1903053 regulation of extracellular matrix disassembly(GO:0010715) negative regulation of extracellular matrix disassembly(GO:0010716) regulation of extracellular matrix organization(GO:1903053) negative regulation of extracellular matrix organization(GO:1903054)
0.0 0.1 GO:0045059 positive thymic T cell selection(GO:0045059)
0.0 0.0 GO:0051290 protein heterotetramerization(GO:0051290)
0.0 0.0 GO:0060997 dendritic spine morphogenesis(GO:0060997) regulation of dendritic spine morphogenesis(GO:0061001) dendritic spine organization(GO:0097061)
0.0 0.0 GO:0010586 miRNA metabolic process(GO:0010586) miRNA catabolic process(GO:0010587)
0.0 0.1 GO:0007191 adenylate cyclase-activating dopamine receptor signaling pathway(GO:0007191)
0.0 0.1 GO:0008535 respiratory chain complex IV assembly(GO:0008535)
0.0 0.0 GO:0002407 dendritic cell chemotaxis(GO:0002407) dendritic cell migration(GO:0036336)
0.0 0.1 GO:0007128 meiotic prophase I(GO:0007128)
0.0 0.1 GO:1901661 quinone metabolic process(GO:1901661)
0.0 0.0 GO:0071072 negative regulation of phospholipid biosynthetic process(GO:0071072)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0070022 transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.0 0.1 GO:0005827 polar microtubule(GO:0005827)
0.0 0.1 GO:0043218 compact myelin(GO:0043218)
0.0 0.1 GO:0030061 mitochondrial crista(GO:0030061)
0.0 0.1 GO:0031313 extrinsic component of vacuolar membrane(GO:0000306) extrinsic component of endosome membrane(GO:0031313)
0.0 0.1 GO:0033268 node of Ranvier(GO:0033268)
0.0 0.2 GO:0001891 phagocytic cup(GO:0001891)
0.0 0.1 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.0 0.1 GO:0030688 preribosome, small subunit precursor(GO:0030688)
0.0 0.1 GO:0017059 palmitoyltransferase complex(GO:0002178) serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211)
0.0 0.1 GO:0071778 obsolete WINAC complex(GO:0071778)
0.0 0.1 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)
0.0 0.3 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.0 0.2 GO:0048786 presynaptic active zone(GO:0048786)
0.0 0.1 GO:0031616 spindle pole centrosome(GO:0031616)
0.0 0.1 GO:0031264 death-inducing signaling complex(GO:0031264)
0.0 0.1 GO:0030127 COPII vesicle coat(GO:0030127)
0.0 0.1 GO:0030992 intraciliary transport particle B(GO:0030992)
0.0 0.1 GO:0032444 activin responsive factor complex(GO:0032444)
0.0 0.1 GO:0000800 lateral element(GO:0000800)
0.0 0.1 GO:0044298 neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.0 0.1 GO:0016593 Cdc73/Paf1 complex(GO:0016593)
0.0 0.0 GO:0031205 endoplasmic reticulum Sec complex(GO:0031205)
0.0 0.1 GO:0005719 nuclear euchromatin(GO:0005719)
0.0 0.1 GO:0035327 transcriptionally active chromatin(GO:0035327)
0.0 0.1 GO:0033256 I-kappaB/NF-kappaB complex(GO:0033256)
0.0 0.0 GO:0005784 Sec61 translocon complex(GO:0005784) translocon complex(GO:0071256)
0.0 0.0 GO:0072487 MSL complex(GO:0072487)
0.0 0.1 GO:0019773 proteasome core complex, alpha-subunit complex(GO:0019773)
0.0 0.0 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.0 0.0 GO:0005672 transcription factor TFIIA complex(GO:0005672)
0.0 0.1 GO:0031254 uropod(GO:0001931) cell trailing edge(GO:0031254)
0.0 0.1 GO:0033018 sarcoplasmic reticulum lumen(GO:0033018)
0.0 0.1 GO:0042101 T cell receptor complex(GO:0042101)
0.0 0.1 GO:0031464 Cul4A-RING E3 ubiquitin ligase complex(GO:0031464)
0.0 0.0 GO:0008540 proteasome regulatory particle, base subcomplex(GO:0008540)
0.0 0.2 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.0 0.1 GO:0017119 Golgi transport complex(GO:0017119)
0.0 0.0 GO:0000137 Golgi cis cisterna(GO:0000137)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0030375 thyroid hormone receptor coactivator activity(GO:0030375)
0.0 0.2 GO:0001846 opsonin binding(GO:0001846)
0.0 0.1 GO:0033691 sialic acid binding(GO:0033691)
0.0 0.2 GO:0046934 phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) phosphatidylinositol bisphosphate kinase activity(GO:0052813)
0.0 0.3 GO:0050786 RAGE receptor binding(GO:0050786)
0.0 0.1 GO:0000987 RNA polymerase II core promoter proximal region sequence-specific DNA binding(GO:0000978) core promoter proximal region sequence-specific DNA binding(GO:0000987) core promoter proximal region DNA binding(GO:0001159)
0.0 0.1 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.0 0.1 GO:0070579 methylcytosine dioxygenase activity(GO:0070579)
0.0 0.2 GO:0005110 frizzled-2 binding(GO:0005110)
0.0 0.1 GO:0047238 glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity(GO:0047238)
0.0 0.1 GO:0017159 pantetheine hydrolase activity(GO:0017159)
0.0 0.1 GO:0004758 serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
0.0 0.1 GO:0005007 fibroblast growth factor-activated receptor activity(GO:0005007)
0.0 0.1 GO:0047894 flavonol 3-sulfotransferase activity(GO:0047894)
0.0 0.2 GO:0004908 interleukin-1 receptor activity(GO:0004908)
0.0 0.1 GO:0070053 thrombospondin receptor activity(GO:0070053)
0.0 0.1 GO:0047035 testosterone dehydrogenase (NAD+) activity(GO:0047035)
0.0 0.1 GO:0031708 bombesin receptor binding(GO:0031705) endothelin B receptor binding(GO:0031708)
0.0 0.2 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.0 0.2 GO:0051787 misfolded protein binding(GO:0051787)
0.0 0.1 GO:0004465 lipoprotein lipase activity(GO:0004465)
0.0 0.1 GO:0004904 interferon receptor activity(GO:0004904)
0.0 0.1 GO:0004833 tryptophan 2,3-dioxygenase activity(GO:0004833)
0.0 0.1 GO:0004594 pantothenate kinase activity(GO:0004594)
0.0 0.1 GO:0050733 RS domain binding(GO:0050733)
0.0 0.1 GO:0009374 biotin binding(GO:0009374)
0.0 0.1 GO:0031849 olfactory receptor binding(GO:0031849)
0.0 0.1 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.0 0.1 GO:0004514 nicotinate-nucleotide diphosphorylase (carboxylating) activity(GO:0004514)
0.0 0.1 GO:0008109 N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109)
0.0 0.1 GO:0003997 acyl-CoA oxidase activity(GO:0003997)
0.0 0.1 GO:0050682 AF-2 domain binding(GO:0050682)
0.0 0.3 GO:0005161 platelet-derived growth factor receptor binding(GO:0005161)
0.0 0.1 GO:0036002 pre-mRNA binding(GO:0036002)
0.0 0.1 GO:0005432 calcium:sodium antiporter activity(GO:0005432)
0.0 0.1 GO:0008545 JUN kinase kinase activity(GO:0008545)
0.0 0.1 GO:0003953 NAD+ nucleosidase activity(GO:0003953)
0.0 0.1 GO:0004939 beta-adrenergic receptor activity(GO:0004939)
0.0 0.1 GO:0015254 glycerol channel activity(GO:0015254)
0.0 0.1 GO:0016882 cyclo-ligase activity(GO:0016882)
0.0 0.1 GO:0042608 T cell receptor binding(GO:0042608)
0.0 0.1 GO:0004551 nucleotide diphosphatase activity(GO:0004551)
0.0 0.1 GO:0070095 fructose-6-phosphate binding(GO:0070095)
0.0 0.1 GO:1901474 azole transporter activity(GO:0045118) azole transmembrane transporter activity(GO:1901474)
0.0 0.1 GO:0003960 NADPH:quinone reductase activity(GO:0003960)
0.0 0.0 GO:0004311 farnesyltranstransferase activity(GO:0004311)
0.0 0.1 GO:0001784 phosphotyrosine binding(GO:0001784)
0.0 0.1 GO:0019136 deoxynucleoside kinase activity(GO:0019136)
0.0 0.1 GO:0070087 chromo shadow domain binding(GO:0070087)
0.0 0.1 GO:0031702 type 1 angiotensin receptor binding(GO:0031702)
0.0 0.1 GO:0015165 pyrimidine nucleotide-sugar transmembrane transporter activity(GO:0015165)
0.0 0.2 GO:0004467 long-chain fatty acid-CoA ligase activity(GO:0004467)
0.0 0.1 GO:0090599 alpha-glucosidase activity(GO:0090599)
0.0 0.0 GO:0001758 retinal dehydrogenase activity(GO:0001758)
0.0 0.0 GO:0004566 beta-glucuronidase activity(GO:0004566)
0.0 0.0 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.0 0.1 GO:0048020 CCR chemokine receptor binding(GO:0048020)
0.0 0.0 GO:0016362 activin receptor activity, type II(GO:0016362)
0.0 0.1 GO:0016778 diphosphotransferase activity(GO:0016778)
0.0 0.3 GO:0019003 GDP binding(GO:0019003)
0.0 0.0 GO:0004911 interleukin-2 receptor activity(GO:0004911)
0.0 0.0 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.0 0.1 GO:0015347 sodium-independent organic anion transmembrane transporter activity(GO:0015347)
0.0 0.0 GO:0004477 methenyltetrahydrofolate cyclohydrolase activity(GO:0004477)
0.0 0.1 GO:0016986 obsolete transcription initiation factor activity(GO:0016986)
0.0 0.0 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 0.1 GO:0004303 estradiol 17-beta-dehydrogenase activity(GO:0004303)
0.0 0.0 GO:0016509 long-chain-3-hydroxyacyl-CoA dehydrogenase activity(GO:0016509)
0.0 0.0 GO:0019855 calcium channel inhibitor activity(GO:0019855)
0.0 0.0 GO:0016309 1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
0.0 0.2 GO:0008373 sialyltransferase activity(GO:0008373)
0.0 0.0 GO:0003829 beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity(GO:0003829)
0.0 0.1 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.0 0.1 GO:0004630 phospholipase D activity(GO:0004630)
0.0 0.0 GO:0001848 complement binding(GO:0001848)
0.0 0.2 GO:0005344 oxygen transporter activity(GO:0005344)
0.0 0.0 GO:0034236 protein kinase A catalytic subunit binding(GO:0034236)
0.0 0.1 GO:0008273 calcium, potassium:sodium antiporter activity(GO:0008273)
0.0 0.1 GO:0050656 3'-phosphoadenosine 5'-phosphosulfate binding(GO:0050656)
0.0 0.0 GO:0070644 vitamin D response element binding(GO:0070644)
0.0 0.1 GO:0016671 oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor(GO:0016671)
0.0 0.1 GO:0034713 type I transforming growth factor beta receptor binding(GO:0034713)
0.0 0.2 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.0 0.0 GO:0005025 transforming growth factor beta receptor activity, type I(GO:0005025)
0.0 0.1 GO:0004046 aminoacylase activity(GO:0004046)
0.0 0.1 GO:0017176 phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.0 0.1 GO:0030332 cyclin binding(GO:0030332)
0.0 0.0 GO:0016149 translation release factor activity, codon specific(GO:0016149)
0.0 0.0 GO:0019788 NEDD8 transferase activity(GO:0019788)
0.0 0.1 GO:0016493 C-C chemokine receptor activity(GO:0016493)
0.0 0.2 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.0 0.0 GO:0031701 angiotensin receptor binding(GO:0031701)
0.0 0.1 GO:0008199 ferric iron binding(GO:0008199)
0.0 0.0 GO:0019763 immunoglobulin receptor activity(GO:0019763)
0.0 0.0 GO:0047623 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.0 0.1 GO:0004579 dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.0 0.1 GO:0001875 lipopolysaccharide receptor activity(GO:0001875)
0.0 0.0 GO:0032794 GTPase activating protein binding(GO:0032794)
0.0 0.1 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.0 PID NFKAPPAB CANONICAL PATHWAY Canonical NF-kappaB pathway
0.0 0.4 SA PTEN PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.0 0.3 PID THROMBIN PAR4 PATHWAY PAR4-mediated thrombin signaling events
0.0 0.6 PID GMCSF PATHWAY GMCSF-mediated signaling events
0.0 0.1 PID VEGFR1 2 PATHWAY Signaling events mediated by VEGFR1 and VEGFR2
0.0 0.2 PID TCR JNK PATHWAY JNK signaling in the CD4+ TCR pathway
0.0 0.3 PID IL2 STAT5 PATHWAY IL2 signaling events mediated by STAT5
0.0 0.1 SA FAS SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.0 0.2 PID IL8 CXCR1 PATHWAY IL8- and CXCR1-mediated signaling events
0.0 0.0 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.0 0.0 ST JAK STAT PATHWAY Jak-STAT Pathway
0.0 0.3 PID RETINOIC ACID PATHWAY Retinoic acid receptors-mediated signaling
0.0 0.3 SIG PIP3 SIGNALING IN B LYMPHOCYTES Genes related to PIP3 signaling in B lymphocytes
0.0 0.1 PID EPO PATHWAY EPO signaling pathway
0.0 0.1 PID IL8 CXCR2 PATHWAY IL8- and CXCR2-mediated signaling events
0.0 0.1 ST INTERFERON GAMMA PATHWAY Interferon gamma pathway.

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.0 REACTOME AUTODEGRADATION OF THE E3 UBIQUITIN LIGASE COP1 Genes involved in Autodegradation of the E3 ubiquitin ligase COP1
0.0 0.1 REACTOME THE ROLE OF NEF IN HIV1 REPLICATION AND DISEASE PATHOGENESIS Genes involved in The role of Nef in HIV-1 replication and disease pathogenesis
0.0 0.1 REACTOME PROCESSING OF CAPPED INTRON CONTAINING PRE MRNA Genes involved in Processing of Capped Intron-Containing Pre-mRNA
0.0 0.3 REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING Genes involved in Advanced glycosylation endproduct receptor signaling
0.0 0.0 REACTOME GPVI MEDIATED ACTIVATION CASCADE Genes involved in GPVI-mediated activation cascade
0.0 0.2 REACTOME CALNEXIN CALRETICULIN CYCLE Genes involved in Calnexin/calreticulin cycle
0.0 0.2 REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.0 0.1 REACTOME ADP SIGNALLING THROUGH P2RY1 Genes involved in ADP signalling through P2Y purinoceptor 1
0.0 0.1 REACTOME BINDING AND ENTRY OF HIV VIRION Genes involved in Binding and entry of HIV virion
0.0 0.5 REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE Genes involved in Synthesis of PIPs at the plasma membrane
0.0 0.0 REACTOME PHOSPHORYLATION OF THE APC C Genes involved in Phosphorylation of the APC/C
0.0 0.2 REACTOME CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
0.0 0.2 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0 0.0 REACTOME PEPTIDE CHAIN ELONGATION Genes involved in Peptide chain elongation
0.0 0.1 REACTOME GROWTH HORMONE RECEPTOR SIGNALING Genes involved in Growth hormone receptor signaling
0.0 0.2 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.0 0.2 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.0 0.1 REACTOME RAF MAP KINASE CASCADE Genes involved in RAF/MAP kinase cascade
0.0 0.0 REACTOME SOS MEDIATED SIGNALLING Genes involved in SOS-mediated signalling
0.0 0.1 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
0.0 0.1 REACTOME REGULATION OF IFNG SIGNALING Genes involved in Regulation of IFNG signaling
0.0 0.2 REACTOME CHONDROITIN SULFATE BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
0.0 0.3 REACTOME THROMBOXANE SIGNALLING THROUGH TP RECEPTOR Genes involved in Thromboxane signalling through TP receptor
0.0 0.2 REACTOME SIGNALING BY FGFR1 FUSION MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.0 0.0 REACTOME CYCLIN E ASSOCIATED EVENTS DURING G1 S TRANSITION Genes involved in Cyclin E associated events during G1/S transition
0.0 0.1 REACTOME NEPHRIN INTERACTIONS Genes involved in Nephrin interactions
0.0 0.0 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION Genes involved in TRAF6 mediated IRF7 activation
0.0 0.2 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.0 0.1 REACTOME G ALPHA Z SIGNALLING EVENTS Genes involved in G alpha (z) signalling events
0.0 0.1 REACTOME G1 S SPECIFIC TRANSCRIPTION Genes involved in G1/S-Specific Transcription
0.0 0.3 REACTOME IL1 SIGNALING Genes involved in Interleukin-1 signaling
0.0 0.1 REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the early endosome membrane
0.0 0.1 REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.0 0.2 REACTOME IL 2 SIGNALING Genes involved in Interleukin-2 signaling