Project
ENCODE: H3K4me1 ChIP-Seq of primary human cells
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CREMA is a free online tool that recognizes most important transcription factors that change the chromatin state across different samples.

Results for NKX2-3

Z-value: 2.62

Motif logo

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Transcription factors associated with NKX2-3

Gene Symbol Gene ID Gene Info
ENSG00000119919.9 NKX2-3

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE Gene Distance Association probability Pearson corr. coef. P-value Plot
NKX2-3chr10_101297437_10129758848220.196115-0.752.0e-02Click!
NKX2-3chr10_101296443_10129675139070.2089230.599.7e-02Click!
NKX2-3chr10_101310900_101311051182850.152988-0.541.4e-01Click!
NKX2-3chr10_101292231_1012926302600.8840300.521.6e-01Click!
NKX2-3chr10_101311108_101311259184930.152517-0.501.7e-01Click!

Activity of the NKX2-3 motif across conditions

Conditions sorted by the z-value of the NKX2-3 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE) Target Score Top associated gene Gene Info Distance of CRE to TSS CRE/Gene association probability
chr1_206740198_206740524 0.95 RASSF5
Ras association (RalGDS/AF-6) domain family member 5
9868
0.16
chr11_44701415_44701797 0.85 TSPAN18
tetraspanin 18
46409
0.15
chr5_133439080_133439473 0.82 TCF7
transcription factor 7 (T-cell specific, HMG-box)
11126
0.22
chr12_104858836_104859139 0.80 CHST11
carbohydrate (chondroitin 4) sulfotransferase 11
8208
0.28
chr17_48949147_48949351 0.80 TOB1
transducer of ERBB2, 1
3910
0.18
chr14_61864214_61864416 0.77 PRKCH
protein kinase C, eta
6903
0.26
chr7_142943130_142943404 0.74 GSTK1
glutathione S-transferase kappa 1
2081
0.19
chr13_109064405_109064702 0.73 ENSG00000223177
.
110874
0.07
chr7_77336983_77337159 0.73 RSBN1L
round spermatid basic protein 1-like
10603
0.25
chr11_48078680_48078903 0.72 ENSG00000263693
.
39543
0.14
chr17_47897958_47898399 0.72 RP11-304F15.3

25094
0.12
chr19_9972790_9973038 0.72 OLFM2
olfactomedin 2
4070
0.12
chr16_11675079_11675230 0.72 LITAF
lipopolysaccharide-induced TNF factor
5075
0.22
chr13_21120681_21121008 0.68 IFT88
intraflagellar transport 88 homolog (Chlamydomonas)
19741
0.18
chr10_73866244_73866447 0.68 SPOCK2
sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2
17555
0.2
chr6_24869020_24869171 0.68 FAM65B
family with sequence similarity 65, member B
8446
0.2
chr7_106509634_106509916 0.67 PIK3CG
phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma
3851
0.32
chr5_169687872_169688139 0.66 LCP2
lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa)
6295
0.24
chr13_99170038_99170205 0.66 STK24
serine/threonine kinase 24
1400
0.49
chr7_157419982_157420222 0.65 AC005481.5
Uncharacterized protein
13387
0.23
chr3_32344273_32344503 0.64 ENSG00000207857
.
43168
0.14
chr22_31678042_31678193 0.64 PIK3IP1
phosphoinositide-3-kinase interacting protein 1
10264
0.11
chr14_99661475_99661896 0.63 AL162151.4

36932
0.18
chr1_101546458_101546702 0.62 RP11-421L21.3

8364
0.2
chr6_90983179_90983497 0.61 BACH2
BTB and CNC homology 1, basic leucine zipper transcription factor 2
23123
0.22
chr2_99281901_99282052 0.61 MGAT4A
mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme A
2040
0.37
chr8_129551445_129551700 0.60 ENSG00000221351
.
280468
0.01
chr13_114917525_114917690 0.60 RASA3
RAS p21 protein activator 3
19521
0.2
chr5_56487884_56488215 0.60 GPBP1
GC-rich promoter binding protein 1
16276
0.22
chr1_160652903_160653207 0.60 RP11-404F10.2

9743
0.15
chr3_16880178_16880359 0.59 PLCL2
phospholipase C-like 2
46184
0.18
chr3_112725948_112726099 0.59 C3orf17
chromosome 3 open reading frame 17
11984
0.13
chr14_98483971_98484122 0.59 C14orf64
chromosome 14 open reading frame 64
39585
0.23
chr15_55532500_55532813 0.58 RAB27A
RAB27A, member RAS oncogene family
8577
0.22
chr2_85009888_85010121 0.58 DUXAP1
double homeobox A pseudogene 1
32111
0.19
chr5_130624334_130624714 0.58 CDC42SE2
CDC42 small effector 2
24731
0.25
chr21_32560064_32560407 0.58 TIAM1
T-cell lymphoma invasion and metastasis 1
57696
0.15
chr13_40527264_40527478 0.58 ENSG00000212553
.
96007
0.09
chrY_7205980_7206318 0.58 ENSG00000251996
.
3423
0.25
chr2_99087882_99088150 0.57 INPP4A
inositol polyphosphate-4-phosphatase, type I, 107kDa
26603
0.2
chr7_34762905_34763135 0.57 ENSG00000242653
.
30016
0.2
chr22_40326443_40326594 0.57 GRAP2
GRB2-related adaptor protein 2
3877
0.21
chr1_167058654_167058909 0.57 GPA33
glycoprotein A33 (transmembrane)
1087
0.45
chr20_35570220_35570403 0.57 SAMHD1
SAM domain and HD domain 1
9800
0.21
chr2_62431430_62431581 0.57 ENSG00000266097
.
1456
0.39
chr1_151897893_151898044 0.57 THEM4
thioesterase superfamily member 4
15684
0.13
chr3_143574021_143574180 0.56 SLC9A9
solute carrier family 9, subfamily A (NHE9, cation proton antiporter 9), member 9
6727
0.33
chr1_36242427_36242578 0.56 CLSPN
claspin
6934
0.17
chr1_26100660_26100867 0.56 SEPN1
selenoprotein N, 1
25904
0.11
chr14_31045998_31046149 0.56 G2E3
G2/M-phase specific E3 ubiquitin protein ligase
889
0.61
chr6_17696354_17696716 0.56 RP11-500C11.3

9953
0.16
chr14_99711451_99711702 0.56 AL109767.1

17709
0.2
chr1_90133579_90133811 0.55 LRRC8C
leucine rich repeat containing 8 family, member C
35064
0.14
chr14_98871416_98871598 0.55 ENSG00000241757
.
53506
0.16
chr7_150438932_150439083 0.55 GIMAP5
GTPase, IMAP family member 5
4571
0.18
chr3_56788277_56788649 0.55 ARHGEF3
Rho guanine nucleotide exchange factor (GEF) 3
21132
0.24
chr6_11380234_11380472 0.55 NEDD9
neural precursor cell expressed, developmentally down-regulated 9
2179
0.43
chr9_127958620_127958997 0.54 RABEPK
Rab9 effector protein with kelch motifs
4013
0.19
chr3_42599327_42599478 0.54 SEC22C
SEC22 vesicle trafficking protein homolog C (S. cerevisiae)
5722
0.15
chr14_99700642_99700829 0.54 AL109767.1

28550
0.18
chr1_100904651_100904881 0.54 RP5-837M10.4

46787
0.13
chr1_112140719_112140870 0.54 RAP1A
RAP1A, member of RAS oncogene family
21605
0.15
chr10_126384646_126384911 0.54 FAM53B-AS1
FAM53B antisense RNA 1
7416
0.22
chr10_111800227_111800378 0.53 ADD3
adducin 3 (gamma)
32580
0.17
chr6_144679009_144679160 0.53 UTRN
utrophin
13847
0.24
chr21_43658442_43658806 0.53 ENSG00000223262
.
17341
0.16
chr6_70499802_70499986 0.53 LMBRD1
LMBR1 domain containing 1
663
0.81
chr3_111328376_111328570 0.53 ZBED2
zinc finger, BED-type containing 2
14183
0.21
chr22_37517061_37517212 0.53 TMPRSS6
transmembrane protease, serine 6
11533
0.11
chr6_137074244_137074465 0.53 MAP3K5
mitogen-activated protein kinase kinase kinase 5
39302
0.16
chr8_121718470_121718621 0.53 RP11-713M15.1

54948
0.15
chr2_234180278_234180686 0.53 ENSG00000252010
.
3891
0.17
chr8_95971501_95971656 0.53 NDUFAF6
NADH dehydrogenase (ubiquinone) complex I, assembly factor 6
1342
0.36
chr15_60849041_60849413 0.52 CTD-2501E16.2

27055
0.16
chr16_28156208_28156427 0.52 XPO6
exportin 6
24905
0.16
chr15_66181382_66181533 0.52 RAB11A
RAB11A, member RAS oncogene family
19106
0.19
chr2_169962538_169962750 0.51 AC007556.3

5391
0.25
chr5_39212705_39213008 0.51 FYB
FYN binding protein
6809
0.3
chr10_26738235_26738386 0.51 APBB1IP
amyloid beta (A4) precursor protein-binding, family B, member 1 interacting protein
10956
0.27
chr2_242044985_242045136 0.51 MTERFD2
MTERF domain containing 2
3313
0.19
chr22_39513310_39513588 0.51 APOBEC3H
apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3H
20169
0.12
chr3_16347339_16347514 0.51 RP11-415F23.2

8520
0.17
chrX_78362545_78362956 0.51 GPR174
G protein-coupled receptor 174
63719
0.15
chr2_198757058_198757209 0.51 PLCL1
phospholipase C-like 1
82151
0.1
chr18_55977490_55977641 0.51 NEDD4L
neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase
12987
0.22
chr17_41328799_41329023 0.51 NBR1
neighbor of BRCA1 gene 1
5651
0.15
chr14_56274665_56274816 0.50 KTN1
kinectin 1 (kinesin receptor)
135092
0.05
chr14_98172880_98173232 0.50 RP11-204N11.1
Uncharacterized protein
56112
0.17
chr10_3799314_3799534 0.50 RP11-184A2.3

6165
0.23
chr1_65535763_65535919 0.50 ENSG00000199135
.
11650
0.19
chr7_114647429_114647687 0.50 MDFIC
MyoD family inhibitor domain containing
73634
0.13
chr6_119397434_119397585 0.50 FAM184A
family with sequence similarity 184, member A
2028
0.32
chr14_61819833_61820004 0.50 PRKCH
protein kinase C, eta
5309
0.24
chr5_150523847_150524170 0.50 ANXA6
annexin A6
2792
0.29
chr10_6607286_6607516 0.50 PRKCQ
protein kinase C, theta
14800
0.3
chr2_134992317_134992525 0.50 ENSG00000222921
.
3655
0.3
chr1_90116505_90116656 0.50 LRRC8C
leucine rich repeat containing 8 family, member C
17949
0.16
chr3_56951565_56952044 0.50 ARHGEF3
Rho guanine nucleotide exchange factor (GEF) 3
1305
0.52
chr1_40527524_40527993 0.50 PPT1
palmitoyl-protein thioesterase 1
20235
0.16
chr2_38871778_38871965 0.50 GALM
galactose mutarotase (aldose 1-epimerase)
21181
0.15
chr21_34614571_34614722 0.49 AP000295.9

4433
0.16
chr14_61808449_61808621 0.49 PRKCH
protein kinase C, eta
2425
0.31
chr5_96285649_96285800 0.49 LNPEP
leucyl/cystinyl aminopeptidase
8431
0.18
chr6_16481024_16481181 0.49 ENSG00000265642
.
52348
0.18
chr20_35361135_35361286 0.49 NDRG3
NDRG family member 3
11020
0.15
chr12_1597402_1597553 0.49 WNT5B
wingless-type MMTV integration site family, member 5B
41580
0.16
chr13_41217849_41218020 0.49 FOXO1
forkhead box O1
22800
0.22
chr2_42445733_42445884 0.49 AC083949.1

48367
0.15
chr14_75992079_75992230 0.49 BATF
basic leucine zipper transcription factor, ATF-like
3251
0.25
chr9_95765717_95765998 0.49 FGD3
FYVE, RhoGEF and PH domain containing 3
11485
0.21
chr1_111175695_111176178 0.48 KCNA2
potassium voltage-gated channel, shaker-related subfamily, member 2
1840
0.34
chr2_136813885_136814194 0.48 AC093391.2

44004
0.15
chr4_109027301_109027793 0.48 LEF1
lymphoid enhancer-binding factor 1
59910
0.12
chr5_55986623_55986775 0.48 AC022431.2
Homo sapiens uncharacterized LOC101928448 (LOC101928448), mRNA.
84640
0.08
chr15_71645703_71645854 0.48 RP11-592N21.2

11115
0.29
chr18_72702111_72702262 0.48 ZADH2
zinc binding alcohol dehydrogenase domain containing 2
215282
0.02
chr10_126385597_126385972 0.48 FAM53B-AS1
FAM53B antisense RNA 1
6410
0.22
chr5_66459653_66459868 0.48 MAST4
microtubule associated serine/threonine kinase family member 4
21498
0.23
chr3_63964329_63964578 0.47 ATXN7
ataxin 7
11033
0.14
chr2_112183307_112183458 0.47 ENSG00000266139
.
104714
0.08
chr3_141222680_141222888 0.47 RASA2
RAS p21 protein activator 2
16893
0.2
chr10_126403615_126403766 0.47 FAM53B-AS1
FAM53B antisense RNA 1
10937
0.18
chrX_135775021_135775217 0.47 CD40LG
CD40 ligand
44733
0.12
chr6_130378208_130378359 0.47 L3MBTL3
l(3)mbt-like 3 (Drosophila)
36581
0.2
chr17_62965440_62965774 0.47 AMZ2P1
archaelysin family metallopeptidase 2 pseudogene 1
4028
0.17
chr19_41811104_41811255 0.47 CCDC97
coiled-coil domain containing 97
4915
0.12
chr3_33102387_33102538 0.47 GLB1
galactosidase, beta 1
35822
0.13
chr16_12629426_12629577 0.47 RP11-552C15.1

9838
0.21
chr8_121750897_121751056 0.47 RP11-713M15.1

22517
0.23
chr9_132790949_132791133 0.47 FNBP1
formin binding protein 1
14400
0.19
chr17_80158027_80158404 0.47 CCDC57
coiled-coil domain containing 57
12474
0.1
chr3_31265925_31266177 0.47 ENSG00000222983
.
4156
0.33
chr8_64100140_64100291 0.47 YTHDF3
YTH domain family, member 3
127
0.97
chr13_30944981_30945174 0.47 KATNAL1
katanin p60 subunit A-like 1
63456
0.13
chr2_197015707_197015858 0.47 RP11-347P5.1

205
0.94
chr1_206740944_206741168 0.47 RASSF5
Ras association (RalGDS/AF-6) domain family member 5
10563
0.16
chr12_80243450_80243607 0.46 PPP1R12A
protein phosphatase 1, regulatory subunit 12A
23124
0.15
chr20_37654689_37654840 0.46 DHX35
DEAH (Asp-Glu-Ala-His) box polypeptide 35
4248
0.29
chr2_162808795_162809052 0.46 ENSG00000253046
.
33631
0.21
chr3_101302942_101303093 0.46 PCNP
PEST proteolytic signal containing nuclear protein
9977
0.13
chr3_13055323_13055569 0.46 IQSEC1
IQ motif and Sec7 domain 1
26910
0.23
chr2_198139415_198139566 0.46 ANKRD44-IT1
ANKRD44 intronic transcript 1 (non-protein coding)
27753
0.15
chr14_64966533_64967082 0.46 ZBTB1
zinc finger and BTB domain containing 1
3636
0.14
chr7_12262824_12263011 0.46 TMEM106B
transmembrane protein 106B
11968
0.31
chr2_198066645_198066879 0.46 ANKRD44
ankyrin repeat domain 44
4000
0.24
chr17_7357614_7357765 0.46 CHRNB1
cholinergic receptor, nicotinic, beta 1 (muscle)
1224
0.19
chr2_204580998_204581238 0.46 CD28
CD28 molecule
9702
0.24
chr9_117141088_117141335 0.46 AKNA
AT-hook transcription factor
1296
0.48
chr12_47619963_47620114 0.46 PCED1B
PC-esterase domain containing 1B
2710
0.31
chr1_228653822_228653973 0.46 ENSG00000266174
.
4122
0.1
chr19_36100517_36101264 0.46 HAUS5
HAUS augmin-like complex, subunit 5
2782
0.13
chr4_53484073_53484286 0.46 USP46
ubiquitin specific peptidase 46
38578
0.16
chr6_139437661_139437842 0.46 HECA
headcase homolog (Drosophila)
18498
0.24
chr5_118701254_118701405 0.45 TNFAIP8
tumor necrosis factor, alpha-induced protein 8
9599
0.22
chr11_73724919_73725168 0.45 UCP3
uncoupling protein 3 (mitochondrial, proton carrier)
4563
0.18
chrX_48930950_48931140 0.45 PRAF2
PRA1 domain family, member 2
603
0.5
chr1_160654460_160654717 0.45 RP11-404F10.2

11276
0.15
chr8_101943957_101944187 0.45 YWHAZ
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta
3211
0.22
chr18_45429266_45429417 0.45 SMAD2
SMAD family member 2
6159
0.26
chr5_67552449_67552681 0.45 PIK3R1
phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
16839
0.26
chr2_197046968_197047186 0.45 STK17B
serine/threonine kinase 17b
5850
0.21
chr6_11382696_11383169 0.45 NEDD9
neural precursor cell expressed, developmentally down-regulated 9
351
0.92
chrX_128889315_128889636 0.45 XPNPEP2
X-prolyl aminopeptidase (aminopeptidase P) 2, membrane-bound
16477
0.19
chr20_51025367_51025552 0.45 ZFP64
ZFP64 zinc finger protein
216934
0.02
chr8_22706569_22706720 0.45 RP11-87E22.2

28841
0.15
chr7_158989752_158989939 0.45 VIPR2
vasoactive intestinal peptide receptor 2
52196
0.18
chr4_149138772_149139058 0.45 RP11-76G10.1

71293
0.13
chr12_94677063_94677247 0.45 RP11-1105G2.3
Uncharacterized protein
3199
0.21
chr16_30486446_30487024 0.45 ITGAL
integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide)
1413
0.16
chr13_41009278_41009488 0.45 ENSG00000252812
.
27806
0.24
chr6_106504703_106504912 0.45 PRDM1
PR domain containing 1, with ZNF domain
29388
0.2
chr7_40010662_40010813 0.45 CDK13
cyclin-dependent kinase 13
20628
0.19
chr1_211446361_211446512 0.45 RCOR3
REST corepressor 3
6144
0.25
chrX_37635148_37635299 0.45 CYBB
cytochrome b-245, beta polypeptide
4041
0.29
chr2_74267178_74267329 0.44 TET3
tet methylcytosine dioxygenase 3
6197
0.2
chrX_13078646_13078839 0.44 FAM9C
family with sequence similarity 9, member C
15941
0.26
chr19_16467370_16467664 0.44 EPS15L1
epidermal growth factor receptor pathway substrate 15-like 1
5247
0.16
chr4_109058056_109058207 0.44 LEF1
lymphoid enhancer-binding factor 1
29326
0.19
chr10_116252938_116253141 0.44 ABLIM1
actin binding LIM protein 1
5287
0.28
chrX_154491822_154491973 0.44 RAB39B
RAB39B, member RAS oncogene family
1977
0.31
chr17_28043336_28043498 0.44 RP11-82O19.1

44704
0.09
chr1_209859954_209860105 0.44 HSD11B1
hydroxysteroid (11-beta) dehydrogenase 1
479
0.75
chr3_4882631_4882782 0.44 ENSG00000239126
.
37680
0.16
chr2_103035509_103035977 0.44 IL18RAP
interleukin 18 receptor accessory protein
162
0.94
chr17_46490235_46490470 0.44 SKAP1
src kinase associated phosphoprotein 1
17200
0.13
chr2_144012089_144012556 0.44 RP11-190J23.1

82581
0.1
chr7_99760518_99760936 0.44 GAL3ST4
galactose-3-O-sulfotransferase 4
4126
0.07
chr6_137710654_137710959 0.44 OLIG3
oligodendrocyte transcription factor 3
104725
0.07
chr7_140752946_140753195 0.44 ENSG00000223212
.
1021
0.57
chr2_192493559_192493729 0.44 NABP1
nucleic acid binding protein 1
49218
0.18
chr1_114393386_114393643 0.44 AP4B1-AS1
AP4B1 antisense RNA 1
5743
0.14
chr14_22998517_22998668 0.44 TRAJ15
T cell receptor alpha joining 15
12
0.96
chr14_103287267_103287455 0.44 TRAF3
TNF receptor-associated factor 3
9330
0.17
chr7_36978892_36979043 0.44 ENSG00000221325
.
19930
0.2
chr13_28015570_28015856 0.43 MTIF3
mitochondrial translational initiation factor 3
8613
0.17
chr20_51677707_51677858 0.43 ENSG00000252629
.
1374
0.51
chr1_121311422_121311588 0.43 FCGR1B
Fc fragment of IgG, high affinity Ib, receptor (CD64)
375568
0.01
chr1_109188369_109188646 0.43 HENMT1
HEN1 methyltransferase homolog 1 (Arabidopsis)
15170
0.19
chr14_71110424_71110575 0.43 TTC9
tetratricopeptide repeat domain 9
1995
0.35
chr1_151793290_151793755 0.43 RORC
RAR-related orphan receptor C
5045
0.08

Histogram of CRE-TSS distances for CREs targeted by :

Histogram of

Rank distribution of CRE target scores:

Histogram of target CRE score.

Distribution of target CREs across different genomic regions:

Weighted Piechart of Weighted Piechart of Weighted Piechart of

Network of associatons between targets according to the STRING database.

StringDB image

First level regulatory network of NKX2-3

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.3 GO:0002326 B cell lineage commitment(GO:0002326)
0.3 1.3 GO:0030854 positive regulation of granulocyte differentiation(GO:0030854)
0.2 0.7 GO:0010459 negative regulation of heart rate(GO:0010459)
0.2 0.6 GO:0002513 tolerance induction to self antigen(GO:0002513)
0.2 0.6 GO:0050862 positive regulation of T cell receptor signaling pathway(GO:0050862)
0.2 0.6 GO:0045722 positive regulation of gluconeogenesis(GO:0045722)
0.2 0.5 GO:0045589 regulation of regulatory T cell differentiation(GO:0045589)
0.2 0.5 GO:0006167 AMP biosynthetic process(GO:0006167)
0.2 1.3 GO:0006491 N-glycan processing(GO:0006491)
0.2 0.5 GO:0007352 zygotic specification of dorsal/ventral axis(GO:0007352)
0.1 0.4 GO:0035405 histone-threonine phosphorylation(GO:0035405)
0.1 0.3 GO:0002313 mature B cell differentiation involved in immune response(GO:0002313)
0.1 0.3 GO:0050857 positive regulation of antigen receptor-mediated signaling pathway(GO:0050857)
0.1 1.1 GO:0007172 signal complex assembly(GO:0007172)
0.1 0.7 GO:0048096 chromatin-mediated maintenance of transcription(GO:0048096)
0.1 0.4 GO:0070602 centromeric sister chromatid cohesion(GO:0070601) regulation of centromeric sister chromatid cohesion(GO:0070602)
0.1 0.4 GO:0019276 UDP-N-acetylgalactosamine metabolic process(GO:0019276)
0.1 0.5 GO:0033152 immunoglobulin V(D)J recombination(GO:0033152)
0.1 0.6 GO:0007023 post-chaperonin tubulin folding pathway(GO:0007023)
0.1 0.6 GO:0007256 activation of JNKK activity(GO:0007256)
0.1 0.2 GO:0031580 membrane raft polarization(GO:0001766) membrane raft distribution(GO:0031580)
0.1 0.2 GO:0034139 regulation of toll-like receptor 3 signaling pathway(GO:0034139)
0.1 0.4 GO:0045074 interleukin-10 biosynthetic process(GO:0042091) regulation of interleukin-10 biosynthetic process(GO:0045074)
0.1 0.1 GO:0042511 regulation of tyrosine phosphorylation of Stat1 protein(GO:0042510) positive regulation of tyrosine phosphorylation of Stat1 protein(GO:0042511)
0.1 1.1 GO:0000381 regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.1 0.3 GO:0001574 ganglioside biosynthetic process(GO:0001574)
0.1 0.5 GO:0090286 cytoskeletal anchoring at nuclear membrane(GO:0090286)
0.1 1.3 GO:0031146 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process(GO:0031146)
0.1 0.4 GO:1901341 activation of store-operated calcium channel activity(GO:0032237) regulation of store-operated calcium channel activity(GO:1901339) positive regulation of store-operated calcium channel activity(GO:1901341)
0.1 0.3 GO:0048537 mucosal-associated lymphoid tissue development(GO:0048537)
0.1 0.4 GO:0070670 response to interleukin-4(GO:0070670)
0.1 1.2 GO:0043368 positive T cell selection(GO:0043368)
0.1 1.0 GO:0050860 negative regulation of antigen receptor-mediated signaling pathway(GO:0050858) negative regulation of T cell receptor signaling pathway(GO:0050860)
0.1 0.1 GO:0050854 regulation of antigen receptor-mediated signaling pathway(GO:0050854) regulation of T cell receptor signaling pathway(GO:0050856)
0.1 0.6 GO:0002063 chondrocyte development(GO:0002063)
0.1 0.4 GO:1904035 endothelial cell apoptotic process(GO:0072577) epithelial cell apoptotic process(GO:1904019) regulation of epithelial cell apoptotic process(GO:1904035) regulation of endothelial cell apoptotic process(GO:2000351)
0.1 0.3 GO:0002691 regulation of cellular extravasation(GO:0002691)
0.1 0.3 GO:0016242 negative regulation of macroautophagy(GO:0016242)
0.1 0.4 GO:0006689 ganglioside catabolic process(GO:0006689)
0.1 0.3 GO:0045341 MHC class I biosynthetic process(GO:0045341) regulation of MHC class I biosynthetic process(GO:0045343)
0.1 0.1 GO:0071803 regulation of podosome assembly(GO:0071801) positive regulation of podosome assembly(GO:0071803)
0.1 0.3 GO:0021542 dentate gyrus development(GO:0021542)
0.1 0.4 GO:0003351 epithelial cilium movement(GO:0003351) epithelial cilium movement involved in determination of left/right asymmetry(GO:0060287)
0.1 0.3 GO:0010956 negative regulation of calcidiol 1-monooxygenase activity(GO:0010956) negative regulation of vitamin D biosynthetic process(GO:0010957) negative regulation of vitamin metabolic process(GO:0046137)
0.1 0.1 GO:0009186 deoxyribonucleoside diphosphate metabolic process(GO:0009186)
0.1 0.1 GO:0033194 response to hydroperoxide(GO:0033194)
0.1 0.6 GO:0051491 positive regulation of filopodium assembly(GO:0051491)
0.1 0.3 GO:0071072 negative regulation of phospholipid biosynthetic process(GO:0071072)
0.1 0.1 GO:0071481 cellular response to X-ray(GO:0071481)
0.1 0.3 GO:0015917 aminophospholipid transport(GO:0015917)
0.1 0.1 GO:0010831 positive regulation of myotube differentiation(GO:0010831)
0.1 0.4 GO:0032926 negative regulation of activin receptor signaling pathway(GO:0032926)
0.1 0.4 GO:0022614 membrane to membrane docking(GO:0022614)
0.1 0.2 GO:0002713 negative regulation of B cell mediated immunity(GO:0002713) negative regulation of immunoglobulin mediated immune response(GO:0002890)
0.1 0.1 GO:0043247 protection from non-homologous end joining at telomere(GO:0031848) telomere maintenance in response to DNA damage(GO:0043247)
0.1 0.4 GO:0045898 regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045898)
0.1 0.4 GO:0060023 soft palate development(GO:0060023)
0.1 0.3 GO:0006772 thiamine metabolic process(GO:0006772)
0.1 0.2 GO:2000114 regulation of establishment of cell polarity(GO:2000114)
0.1 0.2 GO:0030223 neutrophil differentiation(GO:0030223)
0.1 1.5 GO:0060330 regulation of response to interferon-gamma(GO:0060330) regulation of interferon-gamma-mediated signaling pathway(GO:0060334)
0.1 0.4 GO:0042989 sequestering of actin monomers(GO:0042989)
0.1 0.2 GO:0045066 regulatory T cell differentiation(GO:0045066)
0.1 0.1 GO:0002328 pro-B cell differentiation(GO:0002328)
0.1 0.5 GO:0060712 spongiotrophoblast layer development(GO:0060712)
0.1 0.2 GO:0050686 negative regulation of mRNA processing(GO:0050686) negative regulation of mRNA metabolic process(GO:1903312)
0.1 0.2 GO:0018076 N-terminal peptidyl-lysine acetylation(GO:0018076)
0.1 0.3 GO:0017182 peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183)
0.1 0.2 GO:0010815 bradykinin catabolic process(GO:0010815)
0.1 0.2 GO:0031440 regulation of mRNA 3'-end processing(GO:0031440)
0.1 0.4 GO:0006685 sphingomyelin catabolic process(GO:0006685)
0.1 0.2 GO:0030505 inorganic diphosphate transport(GO:0030505)
0.1 0.1 GO:0034135 regulation of toll-like receptor 2 signaling pathway(GO:0034135)
0.1 2.0 GO:0050690 regulation of defense response to virus by virus(GO:0050690)
0.1 0.3 GO:0022038 corpus callosum development(GO:0022038)
0.1 0.4 GO:0045071 negative regulation of viral genome replication(GO:0045071)
0.1 0.2 GO:0021932 hindbrain radial glia guided cell migration(GO:0021932)
0.1 0.2 GO:0043320 natural killer cell activation involved in immune response(GO:0002323) natural killer cell degranulation(GO:0043320)
0.1 0.4 GO:0019987 obsolete negative regulation of anti-apoptosis(GO:0019987)
0.1 0.4 GO:0043518 negative regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043518) negative regulation of signal transduction by p53 class mediator(GO:1901797)
0.1 0.2 GO:0042536 negative regulation of tumor necrosis factor biosynthetic process(GO:0042536)
0.1 0.2 GO:0051594 detection of carbohydrate stimulus(GO:0009730) detection of hexose stimulus(GO:0009732) detection of monosaccharide stimulus(GO:0034287) detection of glucose(GO:0051594)
0.1 0.2 GO:0010761 fibroblast migration(GO:0010761)
0.1 0.3 GO:0000301 retrograde transport, vesicle recycling within Golgi(GO:0000301)
0.1 0.2 GO:0000212 meiotic spindle organization(GO:0000212)
0.1 0.2 GO:0051533 positive regulation of NFAT protein import into nucleus(GO:0051533)
0.1 0.1 GO:0051832 evasion or tolerance of host defenses by virus(GO:0019049) avoidance of host defenses(GO:0044413) evasion or tolerance of host defenses(GO:0044415) avoidance of defenses of other organism involved in symbiotic interaction(GO:0051832) evasion or tolerance of defenses of other organism involved in symbiotic interaction(GO:0051834)
0.1 0.2 GO:0001672 regulation of chromatin assembly or disassembly(GO:0001672)
0.1 0.2 GO:0001787 natural killer cell proliferation(GO:0001787)
0.1 0.7 GO:0008608 attachment of spindle microtubules to kinetochore(GO:0008608)
0.1 0.3 GO:0033522 histone H2A ubiquitination(GO:0033522)
0.1 0.1 GO:0071699 olfactory placode formation(GO:0030910) olfactory placode development(GO:0071698) olfactory placode morphogenesis(GO:0071699)
0.1 0.2 GO:0006678 glucosylceramide metabolic process(GO:0006678)
0.1 0.3 GO:0032753 positive regulation of interleukin-4 production(GO:0032753)
0.1 0.1 GO:0032740 positive regulation of interleukin-17 production(GO:0032740)
0.1 0.1 GO:0030859 polarized epithelial cell differentiation(GO:0030859)
0.1 0.1 GO:0001821 histamine secretion(GO:0001821)
0.1 0.1 GO:0090206 negative regulation of cholesterol biosynthetic process(GO:0045541) negative regulation of cholesterol metabolic process(GO:0090206)
0.1 0.2 GO:0034219 carbohydrate transmembrane transport(GO:0034219)
0.1 0.1 GO:1901798 positive regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043517) positive regulation of signal transduction by p53 class mediator(GO:1901798)
0.1 0.1 GO:0019731 antimicrobial humoral response(GO:0019730) antibacterial humoral response(GO:0019731)
0.1 0.3 GO:0030970 retrograde protein transport, ER to cytosol(GO:0030970)
0.1 0.3 GO:0042159 lipoprotein catabolic process(GO:0042159)
0.1 0.4 GO:0035246 peptidyl-arginine N-methylation(GO:0035246)
0.1 0.1 GO:0009048 dosage compensation by inactivation of X chromosome(GO:0009048)
0.1 0.2 GO:0001831 trophectodermal cellular morphogenesis(GO:0001831)
0.1 0.1 GO:0048859 formation of anatomical boundary(GO:0048859)
0.1 0.9 GO:0032012 regulation of ARF protein signal transduction(GO:0032012)
0.1 0.2 GO:0035067 negative regulation of histone acetylation(GO:0035067) negative regulation of protein acetylation(GO:1901984) negative regulation of peptidyl-lysine acetylation(GO:2000757)
0.1 0.1 GO:0085020 protein K6-linked ubiquitination(GO:0085020)
0.1 0.1 GO:0046642 negative regulation of alpha-beta T cell proliferation(GO:0046642)
0.1 0.2 GO:0046479 glycosphingolipid catabolic process(GO:0046479)
0.1 0.4 GO:0006198 cAMP catabolic process(GO:0006198)
0.1 0.3 GO:0010614 negative regulation of cardiac muscle hypertrophy(GO:0010614)
0.1 0.1 GO:0070669 response to interleukin-2(GO:0070669)
0.1 0.5 GO:0015671 oxygen transport(GO:0015671)
0.1 0.1 GO:0048304 positive regulation of isotype switching to IgG isotypes(GO:0048304)
0.1 0.1 GO:0002523 leukocyte migration involved in inflammatory response(GO:0002523)
0.1 0.1 GO:0034392 negative regulation of smooth muscle cell apoptotic process(GO:0034392)
0.1 0.2 GO:0043615 astrocyte cell migration(GO:0043615)
0.1 0.2 GO:0045354 interferon-alpha biosynthetic process(GO:0045349) regulation of interferon-alpha biosynthetic process(GO:0045354)
0.1 0.2 GO:0045084 positive regulation of interleukin-12 biosynthetic process(GO:0045084)
0.1 0.1 GO:0003402 planar cell polarity pathway involved in axis elongation(GO:0003402)
0.1 0.3 GO:0043984 histone H4-K16 acetylation(GO:0043984)
0.1 3.1 GO:0050852 T cell receptor signaling pathway(GO:0050852)
0.1 0.1 GO:0097300 necroptotic process(GO:0070266) programmed necrotic cell death(GO:0097300)
0.1 0.2 GO:0015937 coenzyme A biosynthetic process(GO:0015937)
0.1 0.1 GO:0033080 immature T cell proliferation in thymus(GO:0033080)
0.1 0.5 GO:0045022 early endosome to late endosome transport(GO:0045022) vesicle-mediated transport between endosomal compartments(GO:0098927)
0.1 0.4 GO:0006983 ER overload response(GO:0006983)
0.1 0.2 GO:0010508 positive regulation of autophagy(GO:0010508)
0.1 0.2 GO:0002430 complement receptor mediated signaling pathway(GO:0002430)
0.1 0.3 GO:0036473 intrinsic apoptotic signaling pathway in response to oxidative stress(GO:0008631) cell death in response to oxidative stress(GO:0036473)
0.1 1.3 GO:0032480 negative regulation of type I interferon production(GO:0032480)
0.1 0.1 GO:0072033 renal vesicle formation(GO:0072033)
0.1 0.1 GO:0006007 glucose catabolic process(GO:0006007)
0.1 0.2 GO:0006449 regulation of translational termination(GO:0006449)
0.1 0.1 GO:0015705 iodide transport(GO:0015705)
0.1 0.2 GO:0060992 response to fungicide(GO:0060992)
0.1 0.2 GO:0035025 positive regulation of Rho protein signal transduction(GO:0035025)
0.1 0.5 GO:0043508 negative regulation of JUN kinase activity(GO:0043508)
0.1 0.2 GO:0061099 negative regulation of protein tyrosine kinase activity(GO:0061099)
0.1 0.2 GO:0015691 cadmium ion transport(GO:0015691) cadmium ion transmembrane transport(GO:0070574)
0.1 0.2 GO:0006883 cellular sodium ion homeostasis(GO:0006883)
0.1 0.2 GO:0034501 protein localization to kinetochore(GO:0034501)
0.1 0.1 GO:0033314 mitotic DNA replication checkpoint(GO:0033314)
0.1 0.3 GO:0006287 base-excision repair, gap-filling(GO:0006287)
0.1 0.3 GO:0003310 pancreatic A cell differentiation(GO:0003310)
0.1 0.2 GO:0032653 regulation of interleukin-10 production(GO:0032653)
0.1 0.2 GO:0060159 regulation of dopamine receptor signaling pathway(GO:0060159)
0.1 0.4 GO:0008653 lipopolysaccharide metabolic process(GO:0008653)
0.1 0.3 GO:0000380 alternative mRNA splicing, via spliceosome(GO:0000380)
0.1 0.1 GO:0048861 leukemia inhibitory factor signaling pathway(GO:0048861)
0.1 0.2 GO:0060999 positive regulation of dendritic spine development(GO:0060999)
0.1 0.1 GO:1901985 positive regulation of histone acetylation(GO:0035066) positive regulation of protein acetylation(GO:1901985) positive regulation of peptidyl-lysine acetylation(GO:2000758)
0.1 0.1 GO:0002710 negative regulation of T cell mediated immunity(GO:0002710)
0.1 0.1 GO:0002823 negative regulation of adaptive immune response(GO:0002820) negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains(GO:0002823)
0.1 0.1 GO:0048711 positive regulation of astrocyte differentiation(GO:0048711)
0.1 0.4 GO:0050853 B cell receptor signaling pathway(GO:0050853)
0.0 0.1 GO:0015816 glycine transport(GO:0015816)
0.0 0.1 GO:0035520 monoubiquitinated protein deubiquitination(GO:0035520)
0.0 0.2 GO:0000281 mitotic cytokinesis(GO:0000281)
0.0 0.2 GO:0015886 heme transport(GO:0015886)
0.0 0.5 GO:0000303 response to superoxide(GO:0000303)
0.0 0.1 GO:0006931 substrate-dependent cell migration, cell attachment to substrate(GO:0006931)
0.0 0.3 GO:0051085 chaperone mediated protein folding requiring cofactor(GO:0051085)
0.0 0.1 GO:0070857 regulation of bile acid biosynthetic process(GO:0070857) regulation of bile acid metabolic process(GO:1904251)
0.0 0.2 GO:0006111 regulation of gluconeogenesis(GO:0006111)
0.0 0.4 GO:0043550 regulation of lipid kinase activity(GO:0043550)
0.0 0.2 GO:0071157 negative regulation of cell cycle arrest(GO:0071157)
0.0 0.1 GO:0045351 type I interferon biosynthetic process(GO:0045351)
0.0 0.2 GO:0070934 CRD-mediated mRNA stabilization(GO:0070934)
0.0 0.1 GO:0001743 optic placode formation(GO:0001743)
0.0 0.0 GO:0010572 positive regulation of platelet activation(GO:0010572)
0.0 0.1 GO:0002238 response to molecule of fungal origin(GO:0002238)
0.0 0.1 GO:0035455 response to interferon-alpha(GO:0035455)
0.0 0.3 GO:0016556 mRNA modification(GO:0016556)
0.0 0.4 GO:0002714 positive regulation of B cell mediated immunity(GO:0002714) positive regulation of immunoglobulin mediated immune response(GO:0002891)
0.0 0.3 GO:1902115 regulation of organelle assembly(GO:1902115)
0.0 0.6 GO:0046854 phosphatidylinositol phosphorylation(GO:0046854)
0.0 0.3 GO:0042535 positive regulation of tumor necrosis factor biosynthetic process(GO:0042535)
0.0 0.1 GO:0006562 proline catabolic process(GO:0006562)
0.0 0.1 GO:0002507 tolerance induction(GO:0002507)
0.0 0.4 GO:0002286 T cell activation involved in immune response(GO:0002286)
0.0 0.2 GO:0032968 positive regulation of transcription elongation from RNA polymerase II promoter(GO:0032968)
0.0 0.2 GO:0046501 protoporphyrinogen IX metabolic process(GO:0046501)
0.0 0.2 GO:0043568 positive regulation of insulin-like growth factor receptor signaling pathway(GO:0043568)
0.0 0.1 GO:0007100 mitotic centrosome separation(GO:0007100)
0.0 0.1 GO:0051103 DNA ligation involved in DNA repair(GO:0051103)
0.0 0.1 GO:1901978 positive regulation of spindle checkpoint(GO:0090232) regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090266) positive regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090267) positive regulation of cell cycle checkpoint(GO:1901978) regulation of mitotic spindle checkpoint(GO:1903504)
0.0 0.1 GO:0048478 replication fork protection(GO:0048478)
0.0 0.1 GO:0045056 transcytosis(GO:0045056)
0.0 0.1 GO:0070933 histone H3 deacetylation(GO:0070932) histone H4 deacetylation(GO:0070933)
0.0 0.1 GO:0015015 heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.0 0.1 GO:0046185 aldehyde catabolic process(GO:0046185)
0.0 0.1 GO:0090004 positive regulation of establishment of protein localization to plasma membrane(GO:0090004) positive regulation of protein localization to plasma membrane(GO:1903078) positive regulation of protein localization to cell periphery(GO:1904377)
0.0 0.2 GO:0045116 protein neddylation(GO:0045116)
0.0 0.2 GO:0033539 fatty acid beta-oxidation using acyl-CoA dehydrogenase(GO:0033539)
0.0 0.1 GO:0006189 'de novo' IMP biosynthetic process(GO:0006189)
0.0 0.1 GO:0051970 negative regulation of transmission of nerve impulse(GO:0051970)
0.0 0.1 GO:0042996 regulation of Golgi to plasma membrane protein transport(GO:0042996)
0.0 0.2 GO:0043628 ncRNA 3'-end processing(GO:0043628)
0.0 0.1 GO:0051790 short-chain fatty acid biosynthetic process(GO:0051790)
0.0 0.1 GO:0047484 regulation of response to osmotic stress(GO:0047484)
0.0 0.1 GO:0071921 establishment of sister chromatid cohesion(GO:0034085) cohesin loading(GO:0071921) regulation of cohesin loading(GO:0071922)
0.0 0.1 GO:0000733 DNA strand renaturation(GO:0000733)
0.0 0.1 GO:0034638 phosphatidylcholine catabolic process(GO:0034638)
0.0 0.0 GO:0060648 mammary gland bud morphogenesis(GO:0060648)
0.0 0.2 GO:0071108 protein K48-linked deubiquitination(GO:0071108)
0.0 0.4 GO:0030260 entry into host cell(GO:0030260) entry into host(GO:0044409) entry into cell of other organism involved in symbiotic interaction(GO:0051806) entry into other organism involved in symbiotic interaction(GO:0051828)
0.0 0.2 GO:0032119 sequestering of zinc ion(GO:0032119)
0.0 0.1 GO:0032060 bleb assembly(GO:0032060)
0.0 0.9 GO:0031295 lymphocyte costimulation(GO:0031294) T cell costimulation(GO:0031295)
0.0 0.1 GO:0050687 negative regulation of defense response to virus(GO:0050687)
0.0 1.0 GO:0008633 obsolete activation of pro-apoptotic gene products(GO:0008633)
0.0 0.1 GO:0010447 response to acidic pH(GO:0010447)
0.0 0.2 GO:0090205 positive regulation of cholesterol metabolic process(GO:0090205)
0.0 0.1 GO:0007000 nucleolus organization(GO:0007000)
0.0 0.0 GO:0002360 T cell lineage commitment(GO:0002360)
0.0 0.3 GO:0048013 ephrin receptor signaling pathway(GO:0048013)
0.0 0.5 GO:0007032 endosome organization(GO:0007032)
0.0 0.1 GO:0015801 aromatic amino acid transport(GO:0015801)
0.0 0.5 GO:0045730 respiratory burst(GO:0045730)
0.0 0.2 GO:0060123 regulation of growth hormone secretion(GO:0060123)
0.0 0.3 GO:0043124 negative regulation of I-kappaB kinase/NF-kappaB signaling(GO:0043124)
0.0 0.3 GO:0015693 magnesium ion transport(GO:0015693)
0.0 0.0 GO:0046834 lipid phosphorylation(GO:0046834)
0.0 0.5 GO:0006044 N-acetylglucosamine metabolic process(GO:0006044)
0.0 0.1 GO:0032790 ribosome disassembly(GO:0032790)
0.0 0.2 GO:0006264 mitochondrial DNA replication(GO:0006264)
0.0 0.7 GO:0043487 regulation of RNA stability(GO:0043487)
0.0 0.1 GO:0046101 hypoxanthine biosynthetic process(GO:0046101)
0.0 0.2 GO:0090399 replicative senescence(GO:0090399)
0.0 0.1 GO:0032814 regulation of natural killer cell activation(GO:0032814)
0.0 0.6 GO:0034199 activation of protein kinase A activity(GO:0034199)
0.0 0.1 GO:0006556 S-adenosylmethionine biosynthetic process(GO:0006556)
0.0 0.0 GO:0032878 regulation of establishment or maintenance of cell polarity(GO:0032878)
0.0 0.1 GO:0000089 mitotic metaphase(GO:0000089)
0.0 0.0 GO:0051322 anaphase(GO:0051322)
0.0 0.1 GO:0002032 desensitization of G-protein coupled receptor protein signaling pathway by arrestin(GO:0002032)
0.0 0.4 GO:0031648 protein destabilization(GO:0031648)
0.0 0.2 GO:0070198 protein localization to chromosome, telomeric region(GO:0070198)
0.0 0.0 GO:0035844 cloaca development(GO:0035844) cloacal septation(GO:0060197)
0.0 0.1 GO:0046668 regulation of retinal cell programmed cell death(GO:0046668)
0.0 0.2 GO:0042346 positive regulation of NF-kappaB import into nucleus(GO:0042346)
0.0 0.1 GO:0060972 left/right pattern formation(GO:0060972)
0.0 0.0 GO:0055078 sodium ion homeostasis(GO:0055078)
0.0 0.1 GO:0060088 auditory receptor cell morphogenesis(GO:0002093) auditory receptor cell stereocilium organization(GO:0060088)
0.0 0.0 GO:0060049 regulation of protein glycosylation(GO:0060049)
0.0 0.1 GO:0006089 lactate metabolic process(GO:0006089)
0.0 0.1 GO:0070779 D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
0.0 0.1 GO:0006998 nuclear envelope organization(GO:0006998)
0.0 0.3 GO:0007020 microtubule nucleation(GO:0007020)
0.0 0.0 GO:0032495 response to muramyl dipeptide(GO:0032495)
0.0 0.1 GO:0032486 Rap protein signal transduction(GO:0032486)
0.0 0.1 GO:0060017 parathyroid gland development(GO:0060017)
0.0 0.0 GO:0035588 adenosine receptor signaling pathway(GO:0001973) G-protein coupled purinergic receptor signaling pathway(GO:0035588)
0.0 0.1 GO:0031936 negative regulation of chromatin silencing(GO:0031936)
0.0 0.0 GO:0048563 post-embryonic organ morphogenesis(GO:0048563)
0.0 0.1 GO:0006391 transcription initiation from mitochondrial promoter(GO:0006391)
0.0 0.2 GO:0048240 sperm capacitation(GO:0048240)
0.0 0.1 GO:0045292 mRNA cis splicing, via spliceosome(GO:0045292)
0.0 0.1 GO:0042362 fat-soluble vitamin biosynthetic process(GO:0042362)
0.0 0.3 GO:0042994 cytoplasmic sequestering of transcription factor(GO:0042994)
0.0 0.0 GO:0042094 interleukin-2 biosynthetic process(GO:0042094)
0.0 0.1 GO:0014805 smooth muscle adaptation(GO:0014805)
0.0 0.1 GO:0072367 regulation of lipid transport by regulation of transcription from RNA polymerase II promoter(GO:0072367)
0.0 0.1 GO:0043276 anoikis(GO:0043276)
0.0 0.1 GO:0016081 synaptic vesicle docking(GO:0016081)
0.0 0.1 GO:1903332 regulation of protein folding(GO:1903332)
0.0 0.0 GO:0051014 actin filament severing(GO:0051014)
0.0 0.3 GO:0046519 sphingoid metabolic process(GO:0046519)
0.0 0.1 GO:0010452 histone H3-K36 methylation(GO:0010452)
0.0 0.0 GO:2001021 negative regulation of response to DNA damage stimulus(GO:2001021)
0.0 0.3 GO:0045197 establishment or maintenance of epithelial cell apical/basal polarity(GO:0045197)
0.0 0.1 GO:0070837 dehydroascorbic acid transport(GO:0070837)
0.0 0.0 GO:0097576 vacuole fusion(GO:0097576)
0.0 0.2 GO:0042102 positive regulation of T cell proliferation(GO:0042102)
0.0 0.0 GO:0002448 mast cell mediated immunity(GO:0002448)
0.0 0.2 GO:0002483 antigen processing and presentation of endogenous peptide antigen(GO:0002483) antigen processing and presentation of endogenous peptide antigen via MHC class I(GO:0019885)
0.0 0.1 GO:0006474 N-terminal protein amino acid acetylation(GO:0006474)
0.0 0.1 GO:0007181 transforming growth factor beta receptor complex assembly(GO:0007181)
0.0 0.1 GO:0042118 endothelial cell activation(GO:0042118)
0.0 0.2 GO:0040015 negative regulation of multicellular organism growth(GO:0040015)
0.0 0.3 GO:0045576 mast cell activation(GO:0045576)
0.0 0.4 GO:2001022 positive regulation of response to DNA damage stimulus(GO:2001022)
0.0 0.1 GO:0018343 protein farnesylation(GO:0018343)
0.0 0.2 GO:0048194 COPI-coated vesicle budding(GO:0035964) Golgi vesicle budding(GO:0048194) Golgi transport vesicle coating(GO:0048200) COPI coating of Golgi vesicle(GO:0048205)
0.0 0.0 GO:0014834 skeletal muscle satellite cell maintenance involved in skeletal muscle regeneration(GO:0014834)
0.0 0.1 GO:0030490 maturation of SSU-rRNA(GO:0030490)
0.0 0.2 GO:0048169 regulation of long-term neuronal synaptic plasticity(GO:0048169)
0.0 0.1 GO:0048261 negative regulation of receptor-mediated endocytosis(GO:0048261)
0.0 0.1 GO:0060620 regulation of cholesterol import(GO:0060620) regulation of sterol import(GO:2000909)
0.0 0.1 GO:0015781 pyrimidine nucleotide-sugar transport(GO:0015781)
0.0 0.1 GO:0042088 T-helper 1 type immune response(GO:0042088)
0.0 0.1 GO:0032743 positive regulation of interleukin-2 production(GO:0032743)
0.0 0.1 GO:0018342 protein prenylation(GO:0018342) prenylation(GO:0097354)
0.0 0.7 GO:0006308 DNA catabolic process(GO:0006308)
0.0 0.1 GO:0046831 regulation of RNA export from nucleus(GO:0046831)
0.0 0.2 GO:0002920 regulation of humoral immune response(GO:0002920)
0.0 0.4 GO:0006413 translational initiation(GO:0006413)
0.0 0.1 GO:0034755 iron ion transmembrane transport(GO:0034755)
0.0 0.0 GO:0006369 termination of RNA polymerase II transcription(GO:0006369)
0.0 0.1 GO:0042149 cellular response to glucose starvation(GO:0042149)
0.0 0.3 GO:0050870 positive regulation of T cell activation(GO:0050870) positive regulation of leukocyte cell-cell adhesion(GO:1903039)
0.0 1.2 GO:0031123 RNA 3'-end processing(GO:0031123)
0.0 0.1 GO:0035335 peptidyl-tyrosine dephosphorylation(GO:0035335)
0.0 0.1 GO:0001833 inner cell mass cell proliferation(GO:0001833)
0.0 0.0 GO:0032769 negative regulation of monooxygenase activity(GO:0032769)
0.0 0.0 GO:0046931 pore complex assembly(GO:0046931)
0.0 0.1 GO:0015014 heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.0 0.2 GO:0003084 positive regulation of systemic arterial blood pressure(GO:0003084)
0.0 0.1 GO:0034421 post-translational protein acetylation(GO:0034421)
0.0 0.2 GO:0030206 chondroitin sulfate biosynthetic process(GO:0030206)
0.0 0.4 GO:0015813 L-glutamate transport(GO:0015813)
0.0 0.1 GO:0009301 snRNA transcription(GO:0009301)
0.0 0.4 GO:0015701 bicarbonate transport(GO:0015701)
0.0 0.1 GO:0006296 nucleotide-excision repair, DNA incision, 5'-to lesion(GO:0006296)
0.0 0.3 GO:0032008 positive regulation of TOR signaling(GO:0032008)
0.0 0.7 GO:0043966 histone H3 acetylation(GO:0043966)
0.0 0.6 GO:0007257 activation of JUN kinase activity(GO:0007257)
0.0 0.2 GO:0006265 DNA topological change(GO:0006265)
0.0 0.1 GO:0032729 positive regulation of interferon-gamma production(GO:0032729)
0.0 0.4 GO:0016254 preassembly of GPI anchor in ER membrane(GO:0016254)
0.0 0.1 GO:0060214 endocardium formation(GO:0060214)
0.0 0.6 GO:0046847 filopodium assembly(GO:0046847)
0.0 0.4 GO:0046677 response to antibiotic(GO:0046677)
0.0 0.1 GO:0031498 nucleosome disassembly(GO:0006337) chromatin disassembly(GO:0031498) protein-DNA complex disassembly(GO:0032986)
0.0 0.1 GO:0009804 phenylpropanoid metabolic process(GO:0009698) coumarin metabolic process(GO:0009804)
0.0 0.1 GO:0002902 regulation of B cell apoptotic process(GO:0002902)
0.0 0.3 GO:0048199 vesicle targeting, to, from or within Golgi(GO:0048199)
0.0 0.0 GO:0051608 histamine transport(GO:0051608)
0.0 0.1 GO:0006154 adenosine catabolic process(GO:0006154)
0.0 0.1 GO:0007638 mechanosensory behavior(GO:0007638)
0.0 0.0 GO:0007144 female meiosis I(GO:0007144)
0.0 0.0 GO:1903392 negative regulation of focal adhesion assembly(GO:0051895) negative regulation of cell junction assembly(GO:1901889) negative regulation of adherens junction organization(GO:1903392)
0.0 0.1 GO:0001832 blastocyst growth(GO:0001832)
0.0 0.2 GO:0070193 synaptonemal complex organization(GO:0070193)
0.0 0.1 GO:0042987 amyloid precursor protein catabolic process(GO:0042987)
0.0 0.4 GO:0051607 defense response to virus(GO:0051607)
0.0 0.1 GO:0046015 carbon catabolite regulation of transcription(GO:0045990) regulation of transcription by glucose(GO:0046015)
0.0 0.2 GO:0043392 negative regulation of DNA binding(GO:0043392)
0.0 0.0 GO:0034122 negative regulation of toll-like receptor signaling pathway(GO:0034122)
0.0 0.1 GO:0008298 intracellular mRNA localization(GO:0008298)
0.0 0.0 GO:0032075 positive regulation of nuclease activity(GO:0032075)
0.0 0.3 GO:0043154 negative regulation of cysteine-type endopeptidase activity involved in apoptotic process(GO:0043154) negative regulation of cysteine-type endopeptidase activity(GO:2000117)
0.0 0.3 GO:0000050 urea cycle(GO:0000050)
0.0 0.0 GO:0008628 hormone-mediated apoptotic signaling pathway(GO:0008628)
0.0 0.2 GO:0032456 endocytic recycling(GO:0032456)
0.0 0.2 GO:0009223 pyrimidine deoxyribonucleotide catabolic process(GO:0009223)
0.0 0.1 GO:0021681 cerebellar granular layer development(GO:0021681) cerebellar granular layer morphogenesis(GO:0021683) cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707)
0.0 0.1 GO:0071166 ribonucleoprotein complex localization(GO:0071166)
0.0 0.4 GO:0014823 response to activity(GO:0014823)
0.0 0.1 GO:0022417 protein maturation by protein folding(GO:0022417)
0.0 0.1 GO:0032914 positive regulation of transforming growth factor beta1 production(GO:0032914)
0.0 0.1 GO:0043045 DNA methylation involved in embryo development(GO:0043045) changes to DNA methylation involved in embryo development(GO:1901538)
0.0 0.1 GO:0061154 endothelial tube morphogenesis(GO:0061154)
0.0 0.2 GO:0015807 L-amino acid transport(GO:0015807)
0.0 1.9 GO:0051028 mRNA transport(GO:0051028)
0.0 0.0 GO:0032461 regulation of protein oligomerization(GO:0032459) positive regulation of protein oligomerization(GO:0032461)
0.0 0.2 GO:0043666 regulation of phosphoprotein phosphatase activity(GO:0043666)
0.0 0.1 GO:0021570 rhombomere 4 development(GO:0021570)
0.0 0.0 GO:0046087 cytidine catabolic process(GO:0006216) cytidine deamination(GO:0009972) cytidine metabolic process(GO:0046087)
0.0 0.3 GO:0042776 mitochondrial ATP synthesis coupled proton transport(GO:0042776)
0.0 0.1 GO:0045672 positive regulation of osteoclast differentiation(GO:0045672)
0.0 0.1 GO:0008089 anterograde axonal transport(GO:0008089)
0.0 0.0 GO:0070296 sarcoplasmic reticulum calcium ion transport(GO:0070296)
0.0 0.2 GO:0006903 vesicle targeting(GO:0006903)
0.0 0.2 GO:0042516 regulation of tyrosine phosphorylation of Stat3 protein(GO:0042516)
0.0 0.1 GO:0002862 negative regulation of inflammatory response to antigenic stimulus(GO:0002862)
0.0 0.1 GO:0030187 melatonin metabolic process(GO:0030186) melatonin biosynthetic process(GO:0030187)
0.0 0.5 GO:0000188 inactivation of MAPK activity(GO:0000188)
0.0 1.4 GO:0006959 humoral immune response(GO:0006959)
0.0 0.0 GO:0060054 positive regulation of epithelial cell proliferation involved in wound healing(GO:0060054)
0.0 0.1 GO:0002329 immature B cell differentiation(GO:0002327) pre-B cell differentiation(GO:0002329)
0.0 0.1 GO:0042523 positive regulation of tyrosine phosphorylation of Stat5 protein(GO:0042523)
0.0 0.1 GO:0060084 synaptic transmission involved in micturition(GO:0060084)
0.0 0.1 GO:0032808 lacrimal gland development(GO:0032808)
0.0 0.0 GO:0006273 lagging strand elongation(GO:0006273)
0.0 0.2 GO:0043097 pyrimidine-containing compound salvage(GO:0008655) pyrimidine nucleoside salvage(GO:0043097)
0.0 0.1 GO:0016572 histone phosphorylation(GO:0016572)
0.0 0.0 GO:0090231 regulation of spindle checkpoint(GO:0090231)
0.0 0.0 GO:0002374 cytokine secretion involved in immune response(GO:0002374) regulation of cytokine secretion involved in immune response(GO:0002739) negative regulation of cytokine secretion involved in immune response(GO:0002740)
0.0 0.2 GO:0050957 equilibrioception(GO:0050957)
0.0 0.1 GO:0033169 histone H3-K9 demethylation(GO:0033169)
0.0 0.1 GO:0006855 drug transmembrane transport(GO:0006855)
0.0 0.1 GO:0060710 chorio-allantoic fusion(GO:0060710)
0.0 0.1 GO:0006102 isocitrate metabolic process(GO:0006102)
0.0 0.1 GO:0007064 mitotic sister chromatid cohesion(GO:0007064)
0.0 0.3 GO:0006783 heme biosynthetic process(GO:0006783)
0.0 0.0 GO:0060122 inner ear receptor stereocilium organization(GO:0060122)
0.0 0.1 GO:0006991 response to sterol depletion(GO:0006991) SREBP signaling pathway(GO:0032933) cellular response to sterol depletion(GO:0071501)
0.0 0.4 GO:0007190 activation of adenylate cyclase activity(GO:0007190)
0.0 0.3 GO:0007379 segment specification(GO:0007379)
0.0 0.0 GO:0048539 bone marrow development(GO:0048539)
0.0 0.1 GO:0001955 blood vessel maturation(GO:0001955)
0.0 0.0 GO:0070265 necrotic cell death(GO:0070265)
0.0 0.0 GO:0033688 regulation of osteoblast proliferation(GO:0033688)
0.0 0.1 GO:0006477 protein sulfation(GO:0006477)
0.0 0.1 GO:0002504 antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002504)
0.0 0.0 GO:0007021 tubulin complex assembly(GO:0007021)
0.0 0.0 GO:2001259 positive regulation of calcium ion transmembrane transporter activity(GO:1901021) positive regulation of cation channel activity(GO:2001259)
0.0 0.1 GO:0048739 cardiac muscle fiber development(GO:0048739)
0.0 0.1 GO:0006686 sphingomyelin biosynthetic process(GO:0006686)
0.0 0.0 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797) lens induction in camera-type eye(GO:0060235)
0.0 0.1 GO:0019509 L-methionine biosynthetic process from methylthioadenosine(GO:0019509)
0.0 0.1 GO:0033683 nucleotide-excision repair, DNA incision(GO:0033683)
0.0 1.1 GO:1902807 negative regulation of cell cycle G1/S phase transition(GO:1902807) negative regulation of G1/S transition of mitotic cell cycle(GO:2000134)
0.0 0.1 GO:0048617 embryonic foregut morphogenesis(GO:0048617)
0.0 0.0 GO:0032464 regulation of protein homooligomerization(GO:0032462) positive regulation of protein homooligomerization(GO:0032464)
0.0 0.1 GO:0072498 embryonic skeletal joint morphogenesis(GO:0060272) embryonic skeletal joint development(GO:0072498)
0.0 0.0 GO:0015742 alpha-ketoglutarate transport(GO:0015742)
0.0 0.0 GO:0021569 rhombomere 3 development(GO:0021569)
0.0 0.5 GO:0006885 regulation of pH(GO:0006885)
0.0 0.2 GO:0006890 retrograde vesicle-mediated transport, Golgi to ER(GO:0006890)
0.0 0.5 GO:0000387 spliceosomal snRNP assembly(GO:0000387)
0.0 0.0 GO:0051775 response to redox state(GO:0051775)
0.0 0.1 GO:0051386 regulation of neurotrophin TRK receptor signaling pathway(GO:0051386)
0.0 0.1 GO:0044091 membrane biogenesis(GO:0044091)
0.0 0.6 GO:0006921 cellular component disassembly involved in execution phase of apoptosis(GO:0006921) execution phase of apoptosis(GO:0097194)
0.0 0.1 GO:0045948 positive regulation of translational initiation(GO:0045948)
0.0 0.2 GO:0006465 signal peptide processing(GO:0006465)
0.0 0.1 GO:0046326 positive regulation of glucose import(GO:0046326)
0.0 0.3 GO:0043484 regulation of RNA splicing(GO:0043484)
0.0 0.1 GO:0071392 cellular response to estradiol stimulus(GO:0071392)
0.0 0.1 GO:0050667 homocysteine metabolic process(GO:0050667)
0.0 0.0 GO:0032048 phosphatidylglycerol biosynthetic process(GO:0006655) cardiolipin metabolic process(GO:0032048) cardiolipin biosynthetic process(GO:0032049) phosphatidylglycerol metabolic process(GO:0046471)
0.0 0.2 GO:0051568 histone H3-K4 methylation(GO:0051568)
0.0 0.1 GO:0051657 maintenance of organelle location(GO:0051657)
0.0 0.0 GO:0042109 lymphotoxin A production(GO:0032641) lymphotoxin A biosynthetic process(GO:0042109)
0.0 0.4 GO:1901185 negative regulation of epidermal growth factor receptor signaling pathway(GO:0042059) negative regulation of ERBB signaling pathway(GO:1901185)
0.0 0.0 GO:0042339 keratan sulfate metabolic process(GO:0042339)
0.0 0.1 GO:0070493 thrombin receptor signaling pathway(GO:0070493)
0.0 0.0 GO:0021860 pyramidal neuron differentiation(GO:0021859) pyramidal neuron development(GO:0021860)
0.0 0.1 GO:0007008 outer mitochondrial membrane organization(GO:0007008) protein import into mitochondrial outer membrane(GO:0045040)
0.0 0.1 GO:0035095 behavioral response to nicotine(GO:0035095)
0.0 0.0 GO:0060670 branching involved in labyrinthine layer morphogenesis(GO:0060670)
0.0 0.1 GO:0006610 ribosomal protein import into nucleus(GO:0006610)
0.0 0.0 GO:0030812 negative regulation of nucleotide catabolic process(GO:0030812)
0.0 0.0 GO:0033262 regulation of nuclear cell cycle DNA replication(GO:0033262)
0.0 0.1 GO:0000183 chromatin silencing at rDNA(GO:0000183)
0.0 0.2 GO:0006704 glucocorticoid biosynthetic process(GO:0006704)
0.0 0.0 GO:0034983 peptidyl-lysine deacetylation(GO:0034983)
0.0 0.3 GO:0007339 binding of sperm to zona pellucida(GO:0007339)
0.0 0.1 GO:0030388 fructose 1,6-bisphosphate metabolic process(GO:0030388)
0.0 0.0 GO:0051788 response to misfolded protein(GO:0051788)
0.0 0.2 GO:0070534 protein K63-linked ubiquitination(GO:0070534)
0.0 0.3 GO:0015949 nucleobase-containing small molecule interconversion(GO:0015949)
0.0 0.1 GO:0010907 positive regulation of glucose metabolic process(GO:0010907)
0.0 3.3 GO:0008380 RNA splicing(GO:0008380)
0.0 0.5 GO:0006695 cholesterol biosynthetic process(GO:0006695)
0.0 0.2 GO:0010458 exit from mitosis(GO:0010458)
0.0 0.2 GO:0007217 tachykinin receptor signaling pathway(GO:0007217)
0.0 0.1 GO:0008347 glial cell migration(GO:0008347)
0.0 0.2 GO:0007052 mitotic spindle organization(GO:0007052)
0.0 0.1 GO:0043525 positive regulation of neuron apoptotic process(GO:0043525) positive regulation of neuron death(GO:1901216)
0.0 0.0 GO:0009313 oligosaccharide catabolic process(GO:0009313)
0.0 0.2 GO:0033540 fatty acid beta-oxidation using acyl-CoA oxidase(GO:0033540)
0.0 0.1 GO:0021898 commitment of multipotent stem cells to neuronal lineage in forebrain(GO:0021898)
0.0 0.1 GO:0010984 regulation of lipoprotein particle clearance(GO:0010984)
0.0 0.1 GO:0050851 antigen receptor-mediated signaling pathway(GO:0050851)
0.0 0.0 GO:0010758 regulation of macrophage chemotaxis(GO:0010758)
0.0 0.0 GO:0007063 regulation of sister chromatid cohesion(GO:0007063)
0.0 0.1 GO:1901072 amino sugar catabolic process(GO:0046348) glucosamine-containing compound catabolic process(GO:1901072)
0.0 0.0 GO:2000144 positive regulation of transcription initiation from RNA polymerase II promoter(GO:0060261) positive regulation of DNA-templated transcription, initiation(GO:2000144)
0.0 0.0 GO:0052251 induction by organism of defense response of other organism involved in symbiotic interaction(GO:0052251)
0.0 0.1 GO:0031334 positive regulation of protein complex assembly(GO:0031334)
0.0 0.1 GO:0032292 myelination in peripheral nervous system(GO:0022011) peripheral nervous system axon ensheathment(GO:0032292)
0.0 0.1 GO:0034372 triglyceride-rich lipoprotein particle remodeling(GO:0034370) very-low-density lipoprotein particle remodeling(GO:0034372)
0.0 0.2 GO:0042744 hydrogen peroxide catabolic process(GO:0042744)
0.0 0.1 GO:0009812 flavonoid metabolic process(GO:0009812)
0.0 0.0 GO:0051459 corticotropin secretion(GO:0051458) regulation of corticotropin secretion(GO:0051459) positive regulation of corticotropin secretion(GO:0051461)
0.0 0.0 GO:0030011 maintenance of cell polarity(GO:0030011)
0.0 0.0 GO:0048752 semicircular canal morphogenesis(GO:0048752) semicircular canal development(GO:0060872)
0.0 0.0 GO:0000019 regulation of mitotic recombination(GO:0000019)
0.0 0.1 GO:0032922 circadian regulation of gene expression(GO:0032922)
0.0 0.0 GO:0006779 porphyrin-containing compound biosynthetic process(GO:0006779)
0.0 0.1 GO:0071445 obsolete cellular response to protein stimulus(GO:0071445)
0.0 0.1 GO:0051927 obsolete negative regulation of calcium ion transport via voltage-gated calcium channel activity(GO:0051927)
0.0 0.0 GO:0042695 thelarche(GO:0042695) development of secondary sexual characteristics(GO:0045136) development of secondary female sexual characteristics(GO:0046543) mammary gland branching involved in thelarche(GO:0060744)
0.0 0.0 GO:0035305 negative regulation of dephosphorylation(GO:0035305) negative regulation of protein dephosphorylation(GO:0035308)
0.0 0.0 GO:0030174 regulation of DNA-dependent DNA replication initiation(GO:0030174)
0.0 0.1 GO:0045603 positive regulation of endothelial cell differentiation(GO:0045603)
0.0 0.2 GO:0071577 zinc II ion transmembrane transport(GO:0071577)
0.0 0.1 GO:0021794 thalamus development(GO:0021794)
0.0 0.3 GO:0006626 protein targeting to mitochondrion(GO:0006626)
0.0 0.1 GO:0042168 heme metabolic process(GO:0042168)
0.0 0.0 GO:0002438 acute inflammatory response to antigenic stimulus(GO:0002438)
0.0 0.0 GO:0010826 negative regulation of centrosome duplication(GO:0010826) negative regulation of centrosome cycle(GO:0046606)
0.0 0.1 GO:0051852 disruption by host of symbiont cells(GO:0051852) killing by host of symbiont cells(GO:0051873)
0.0 0.0 GO:0051901 positive regulation of mitochondrial depolarization(GO:0051901) positive regulation of membrane depolarization(GO:1904181)
0.0 0.0 GO:0006684 sphingomyelin metabolic process(GO:0006684)
0.0 0.5 GO:0016579 protein deubiquitination(GO:0016579)
0.0 0.0 GO:0006930 substrate-dependent cell migration, cell extension(GO:0006930)
0.0 0.0 GO:0021936 regulation of cerebellar granule cell precursor proliferation(GO:0021936) positive regulation of cerebellar granule cell precursor proliferation(GO:0021940)
0.0 0.0 GO:0045910 negative regulation of DNA recombination(GO:0045910)
0.0 0.1 GO:0010165 response to X-ray(GO:0010165)
0.0 0.1 GO:0006658 phosphatidylserine metabolic process(GO:0006658)
0.0 0.7 GO:0030041 actin filament polymerization(GO:0030041)
0.0 0.0 GO:0016577 histone demethylation(GO:0016577)
0.0 0.1 GO:0061077 chaperone-mediated protein folding(GO:0061077)
0.0 0.1 GO:0006554 lysine metabolic process(GO:0006553) lysine catabolic process(GO:0006554)
0.0 0.1 GO:0051220 cytoplasmic sequestering of protein(GO:0051220)
0.0 0.1 GO:0070293 renal absorption(GO:0070293)
0.0 0.0 GO:0001661 conditioned taste aversion(GO:0001661)
0.0 0.1 GO:0034227 tRNA wobble base modification(GO:0002097) tRNA wobble uridine modification(GO:0002098) tRNA thio-modification(GO:0034227)
0.0 0.1 GO:0016266 O-glycan processing(GO:0016266)
0.0 0.0 GO:0006614 SRP-dependent cotranslational protein targeting to membrane(GO:0006614)
0.0 0.1 GO:0006997 nucleus organization(GO:0006997)
0.0 0.0 GO:0071542 dopaminergic neuron differentiation(GO:0071542)
0.0 0.1 GO:0015851 nucleobase transport(GO:0015851)
0.0 1.0 GO:0018196 peptidyl-asparagine modification(GO:0018196) protein N-linked glycosylation via asparagine(GO:0018279)
0.0 0.2 GO:0043252 sodium-independent organic anion transport(GO:0043252)
0.0 0.1 GO:0051298 centrosome duplication(GO:0051298)
0.0 0.0 GO:0040023 establishment of nucleus localization(GO:0040023)
0.0 0.2 GO:0000083 regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083)
0.0 0.2 GO:0065002 intracellular protein transmembrane transport(GO:0065002) protein transmembrane transport(GO:0071806)
0.0 0.1 GO:0007076 mitotic chromosome condensation(GO:0007076)
0.0 0.0 GO:0045943 positive regulation of transcription from RNA polymerase I promoter(GO:0045943)
0.0 0.0 GO:0090273 somatostatin secretion(GO:0070253) regulation of somatostatin secretion(GO:0090273)
0.0 0.1 GO:0042249 establishment of planar polarity of embryonic epithelium(GO:0042249)
0.0 0.0 GO:0042538 hyperosmotic salinity response(GO:0042538) lung saccule development(GO:0060430) Type II pneumocyte differentiation(GO:0060510)
0.0 0.0 GO:0034379 very-low-density lipoprotein particle assembly(GO:0034379)
0.0 0.1 GO:0006105 succinate metabolic process(GO:0006105)
0.0 0.1 GO:0001514 selenocysteine incorporation(GO:0001514) translational readthrough(GO:0006451)
0.0 0.0 GO:0044650 virion attachment to host cell(GO:0019062) adhesion of symbiont to host cell(GO:0044650)
0.0 0.1 GO:1904031 positive regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045737) positive regulation of cyclin-dependent protein kinase activity(GO:1904031)
0.0 0.1 GO:0007141 male meiosis I(GO:0007141)
0.0 0.2 GO:0000080 mitotic G1 phase(GO:0000080)
0.0 0.0 GO:1904376 negative regulation of establishment of protein localization to plasma membrane(GO:0090005) negative regulation of protein localization to plasma membrane(GO:1903077) negative regulation of protein localization to cell periphery(GO:1904376)
0.0 0.1 GO:0001510 RNA methylation(GO:0001510)
0.0 0.0 GO:0070979 protein K11-linked ubiquitination(GO:0070979)
0.0 0.0 GO:0042819 pyridoxine metabolic process(GO:0008614) pyridoxine biosynthetic process(GO:0008615) vitamin B6 metabolic process(GO:0042816) vitamin B6 biosynthetic process(GO:0042819)
0.0 0.1 GO:0060040 retinal bipolar neuron differentiation(GO:0060040)
0.0 0.1 GO:0006359 regulation of transcription from RNA polymerase III promoter(GO:0006359)
0.0 0.2 GO:0050832 defense response to fungus(GO:0050832)
0.0 0.1 GO:0018026 peptidyl-lysine monomethylation(GO:0018026)
0.0 0.1 GO:0016574 histone ubiquitination(GO:0016574)
0.0 0.1 GO:0008343 adult feeding behavior(GO:0008343)
0.0 0.2 GO:0051225 spindle assembly(GO:0051225)
0.0 0.0 GO:0060766 negative regulation of androgen receptor signaling pathway(GO:0060766)
0.0 0.0 GO:0003056 regulation of vascular smooth muscle contraction(GO:0003056)
0.0 0.2 GO:0016236 macroautophagy(GO:0016236)
0.0 0.0 GO:0032906 transforming growth factor beta2 production(GO:0032906) regulation of transforming growth factor beta2 production(GO:0032909)
0.0 0.1 GO:0051324 prophase(GO:0051324)
0.0 0.1 GO:0006600 creatine metabolic process(GO:0006600)
0.0 0.0 GO:0046631 alpha-beta T cell activation(GO:0046631)
0.0 0.2 GO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:0000184)
0.0 0.1 GO:0007062 sister chromatid cohesion(GO:0007062)
0.0 0.1 GO:0021513 spinal cord dorsal/ventral patterning(GO:0021513)
0.0 0.1 GO:0006546 glycine catabolic process(GO:0006546)
0.0 0.0 GO:0072583 synaptic vesicle recycling(GO:0036465) synaptic vesicle endocytosis(GO:0048488) clathrin-mediated endocytosis(GO:0072583)
0.0 0.4 GO:0000236 mitotic prometaphase(GO:0000236)
0.0 0.1 GO:0033687 osteoblast proliferation(GO:0033687)
0.0 0.1 GO:0022408 negative regulation of cell-cell adhesion(GO:0022408)
0.0 0.1 GO:0045668 negative regulation of osteoblast differentiation(GO:0045668)
0.0 0.1 GO:0000154 rRNA modification(GO:0000154)
0.0 0.1 GO:0031122 cytoplasmic microtubule organization(GO:0031122)
0.0 0.0 GO:0009151 purine deoxyribonucleotide metabolic process(GO:0009151)
0.0 0.0 GO:0017085 response to insecticide(GO:0017085)
0.0 0.1 GO:0010833 telomere maintenance via telomere lengthening(GO:0010833)
0.0 0.1 GO:0006555 methionine metabolic process(GO:0006555)
0.0 0.1 GO:0015074 DNA integration(GO:0015074)
0.0 0.0 GO:0006984 ER-nucleus signaling pathway(GO:0006984)
0.0 0.1 GO:0015939 pantothenate metabolic process(GO:0015939)
0.0 0.0 GO:0030149 sphingolipid catabolic process(GO:0030149)
0.0 0.5 GO:0006338 chromatin remodeling(GO:0006338)
0.0 0.1 GO:0009253 peptidoglycan metabolic process(GO:0000270) peptidoglycan catabolic process(GO:0009253)
0.0 0.8 GO:0022904 respiratory electron transport chain(GO:0022904)
0.0 0.0 GO:0035283 central nervous system segmentation(GO:0035283) brain segmentation(GO:0035284)
0.0 0.0 GO:0006975 DNA damage induced protein phosphorylation(GO:0006975)
0.0 0.1 GO:0006305 DNA alkylation(GO:0006305) DNA methylation(GO:0006306)
0.0 0.0 GO:0000076 DNA replication checkpoint(GO:0000076)
0.0 0.0 GO:0032494 response to peptidoglycan(GO:0032494)
0.0 0.0 GO:0060080 inhibitory postsynaptic potential(GO:0060080)
0.0 0.8 GO:0006415 translational termination(GO:0006415)
0.0 0.0 GO:0046513 ceramide biosynthetic process(GO:0046513)
0.0 0.0 GO:0043049 otic placode formation(GO:0043049)
0.0 0.2 GO:0045814 negative regulation of gene expression, epigenetic(GO:0045814)
0.0 0.0 GO:0044803 multi-organism membrane organization(GO:0044803)
0.0 0.2 GO:0006513 protein monoubiquitination(GO:0006513)
0.0 0.9 GO:0034248 regulation of cellular amide metabolic process(GO:0034248)
0.0 0.0 GO:0071636 positive regulation of transforming growth factor beta production(GO:0071636)
0.0 0.0 GO:0000028 ribosomal small subunit assembly(GO:0000028)
0.0 0.1 GO:0048873 homeostasis of number of cells within a tissue(GO:0048873)
0.0 0.0 GO:0006642 triglyceride mobilization(GO:0006642)
0.0 0.0 GO:0042448 progesterone metabolic process(GO:0042448)
0.0 0.0 GO:0090501 RNA phosphodiester bond hydrolysis(GO:0090501)
0.0 0.0 GO:0043569 negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569)
0.0 0.1 GO:0008156 negative regulation of DNA replication(GO:0008156)
0.0 0.2 GO:1903363 negative regulation of cellular protein catabolic process(GO:1903363)
0.0 0.2 GO:0051289 protein homotetramerization(GO:0051289)
0.0 0.1 GO:0070189 kynurenine metabolic process(GO:0070189)
0.0 0.0 GO:0019377 glycolipid catabolic process(GO:0019377)
0.0 0.0 GO:0006498 N-terminal protein lipidation(GO:0006498)
0.0 0.1 GO:0018106 peptidyl-histidine phosphorylation(GO:0018106) peptidyl-histidine modification(GO:0018202)
0.0 0.0 GO:0051095 regulation of helicase activity(GO:0051095)
0.0 0.0 GO:0014068 positive regulation of phosphatidylinositol 3-kinase signaling(GO:0014068)
0.0 0.0 GO:0003207 cardiac chamber formation(GO:0003207) cardiac ventricle formation(GO:0003211)
0.0 0.4 GO:0006397 mRNA processing(GO:0006397)
0.0 0.1 GO:0042596 fear response(GO:0042596)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 GO:0070022 transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.2 0.6 GO:0032444 activin responsive factor complex(GO:0032444)
0.1 1.2 GO:0001891 phagocytic cup(GO:0001891)
0.1 1.6 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.1 0.5 GO:0034993 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.1 0.5 GO:0034045 pre-autophagosomal structure membrane(GO:0034045)
0.1 1.2 GO:0001772 immunological synapse(GO:0001772)
0.1 0.3 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)
0.1 0.3 GO:0000942 condensed nuclear chromosome outer kinetochore(GO:0000942)
0.1 1.2 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.1 0.3 GO:0072487 MSL complex(GO:0072487)
0.1 0.3 GO:0016604 nuclear body(GO:0016604)
0.1 0.3 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.1 0.2 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.1 0.8 GO:0031080 nuclear pore outer ring(GO:0031080)
0.1 0.4 GO:0070695 FHF complex(GO:0070695)
0.1 0.1 GO:0001740 Barr body(GO:0001740)
0.1 0.1 GO:0030125 clathrin vesicle coat(GO:0030125)
0.1 0.1 GO:0031465 Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
0.1 0.3 GO:0000300 obsolete peripheral to membrane of membrane fraction(GO:0000300)
0.1 0.8 GO:0035631 CD40 receptor complex(GO:0035631)
0.1 1.5 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.1 0.1 GO:0000306 extrinsic component of vacuolar membrane(GO:0000306) extrinsic component of endosome membrane(GO:0031313)
0.1 0.7 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.1 2.3 GO:0030175 filopodium(GO:0030175)
0.1 0.3 GO:0005797 Golgi medial cisterna(GO:0005797)
0.1 0.1 GO:0030132 clathrin coat of coated pit(GO:0030132)
0.1 0.4 GO:0031264 death-inducing signaling complex(GO:0031264)
0.1 1.0 GO:0030530 obsolete heterogeneous nuclear ribonucleoprotein complex(GO:0030530)
0.1 0.7 GO:0043209 myelin sheath(GO:0043209)
0.1 0.1 GO:0030062 mitochondrial tricarboxylic acid cycle enzyme complex(GO:0030062)
0.1 0.2 GO:0005827 polar microtubule(GO:0005827)
0.1 0.1 GO:0031932 TORC2 complex(GO:0031932)
0.1 0.3 GO:0033256 I-kappaB/NF-kappaB complex(GO:0033256)
0.1 0.3 GO:0045240 dihydrolipoyl dehydrogenase complex(GO:0045240)
0.1 0.3 GO:0044224 juxtaparanode region of axon(GO:0044224)
0.1 0.1 GO:0032449 CBM complex(GO:0032449)
0.1 0.2 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.1 0.5 GO:0034518 mRNA cap binding complex(GO:0005845) RNA cap binding complex(GO:0034518)
0.1 0.2 GO:0030895 apolipoprotein B mRNA editing enzyme complex(GO:0030895)
0.1 0.5 GO:0030877 beta-catenin destruction complex(GO:0030877)
0.1 0.2 GO:0005639 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229) nuclear membrane part(GO:0044453)
0.0 0.3 GO:0070688 MLL5-L complex(GO:0070688)
0.0 0.5 GO:0019908 nuclear cyclin-dependent protein kinase holoenzyme complex(GO:0019908)
0.0 0.1 GO:0070188 obsolete Stn1-Ten1 complex(GO:0070188)
0.0 0.1 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
0.0 0.1 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.0 0.1 GO:0000178 exosome (RNase complex)(GO:0000178)
0.0 0.4 GO:0016585 obsolete chromatin remodeling complex(GO:0016585)
0.0 0.7 GO:0016514 SWI/SNF complex(GO:0016514)
0.0 0.1 GO:1990316 ATG1/ULK1 kinase complex(GO:1990316)
0.0 0.2 GO:0031088 platelet dense granule membrane(GO:0031088)
0.0 0.7 GO:0005844 polysome(GO:0005844)
0.0 0.1 GO:0071001 U4/U6 snRNP(GO:0071001)
0.0 0.1 GO:0030891 VCB complex(GO:0030891)
0.0 0.2 GO:0070531 BRCA1-A complex(GO:0070531)
0.0 0.2 GO:0000791 euchromatin(GO:0000791)
0.0 0.2 GO:0000444 MIS12/MIND type complex(GO:0000444)
0.0 0.1 GO:0005787 signal peptidase complex(GO:0005787)
0.0 1.3 GO:0005626 obsolete insoluble fraction(GO:0005626)
0.0 0.2 GO:0001931 uropod(GO:0001931) cell trailing edge(GO:0031254)
0.0 0.4 GO:0000242 pericentriolar material(GO:0000242)
0.0 0.2 GO:0031464 Cul4A-RING E3 ubiquitin ligase complex(GO:0031464)
0.0 0.2 GO:0070775 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.0 0.1 GO:0071778 obsolete WINAC complex(GO:0071778)
0.0 0.2 GO:0030121 AP-1 adaptor complex(GO:0030121)
0.0 0.2 GO:0042382 paraspeckles(GO:0042382)
0.0 0.1 GO:0005652 nuclear lamina(GO:0005652)
0.0 0.1 GO:0070937 CRD-mediated mRNA stability complex(GO:0070937)
0.0 0.3 GO:0042589 zymogen granule membrane(GO:0042589)
0.0 0.2 GO:0045179 apical cortex(GO:0045179)
0.0 0.4 GO:0033276 transcription factor TFTC complex(GO:0033276)
0.0 0.2 GO:0042598 obsolete vesicular fraction(GO:0042598)
0.0 0.2 GO:0030893 meiotic cohesin complex(GO:0030893)
0.0 0.7 GO:0005637 nuclear inner membrane(GO:0005637)
0.0 0.2 GO:0031082 BLOC complex(GO:0031082) BLOC-1 complex(GO:0031083)
0.0 0.1 GO:0032133 chromosome passenger complex(GO:0032133)
0.0 0.0 GO:0030684 preribosome(GO:0030684)
0.0 0.0 GO:0005657 replication fork(GO:0005657)
0.0 0.3 GO:0042101 T cell receptor complex(GO:0042101)
0.0 0.1 GO:0001652 granular component(GO:0001652)
0.0 0.1 GO:0042405 nuclear inclusion body(GO:0042405)
0.0 0.1 GO:0048179 activin receptor complex(GO:0048179)
0.0 0.2 GO:0005869 dynactin complex(GO:0005869)
0.0 0.2 GO:0000109 nucleotide-excision repair complex(GO:0000109)
0.0 0.2 GO:0031010 ISWI-type complex(GO:0031010)
0.0 0.2 GO:0043190 ATP-binding cassette (ABC) transporter complex(GO:0043190)
0.0 0.1 GO:0005900 oncostatin-M receptor complex(GO:0005900)
0.0 0.2 GO:0000275 mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275)
0.0 0.1 GO:0035189 Rb-E2F complex(GO:0035189)
0.0 0.1 GO:0070552 BRISC complex(GO:0070552)
0.0 0.3 GO:0005671 Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
0.0 0.1 GO:0032809 neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.0 0.1 GO:0072357 PTW/PP1 phosphatase complex(GO:0072357)
0.0 0.3 GO:0045120 pronucleus(GO:0045120)
0.0 0.3 GO:0005732 small nucleolar ribonucleoprotein complex(GO:0005732)
0.0 0.2 GO:0032838 cell projection cytoplasm(GO:0032838)
0.0 1.4 GO:0016605 PML body(GO:0016605)
0.0 0.2 GO:0008290 F-actin capping protein complex(GO:0008290)
0.0 0.1 GO:0032590 dendrite membrane(GO:0032590)
0.0 0.6 GO:0030660 Golgi-associated vesicle membrane(GO:0030660)
0.0 0.3 GO:0005852 eukaryotic translation initiation factor 3 complex(GO:0005852)
0.0 0.1 GO:0032009 early phagosome(GO:0032009)
0.0 0.2 GO:0034362 low-density lipoprotein particle(GO:0034362)
0.0 0.1 GO:0033553 rDNA heterochromatin(GO:0033553)
0.0 0.2 GO:0046581 intercellular canaliculus(GO:0046581)
0.0 0.1 GO:0005678 obsolete chromatin assembly complex(GO:0005678)
0.0 0.0 GO:0000176 nuclear exosome (RNase complex)(GO:0000176)
0.0 0.1 GO:0005641 nuclear envelope lumen(GO:0005641)
0.0 0.1 GO:0002080 acrosomal membrane(GO:0002080)
0.0 0.2 GO:0005680 anaphase-promoting complex(GO:0005680)
0.0 0.4 GO:0032420 stereocilium(GO:0032420)
0.0 0.4 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.0 0.1 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.0 1.1 GO:0055037 recycling endosome(GO:0055037)
0.0 0.4 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)
0.0 0.1 GO:0048786 presynaptic active zone(GO:0048786)
0.0 0.4 GO:0016328 lateral plasma membrane(GO:0016328)
0.0 0.2 GO:0032040 small-subunit processome(GO:0032040)
0.0 0.1 GO:0017059 palmitoyltransferase complex(GO:0002178) serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211)
0.0 0.1 GO:0005786 signal recognition particle, endoplasmic reticulum targeting(GO:0005786) signal recognition particle(GO:0048500)
0.0 0.1 GO:0071204 histone pre-mRNA 3'end processing complex(GO:0071204)
0.0 1.7 GO:0048770 melanosome(GO:0042470) pigment granule(GO:0048770)
0.0 1.1 GO:0005643 nuclear pore(GO:0005643)
0.0 0.9 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.0 0.2 GO:0032156 septin complex(GO:0031105) septin cytoskeleton(GO:0032156)
0.0 0.1 GO:0016600 flotillin complex(GO:0016600)
0.0 0.0 GO:0045239 tricarboxylic acid cycle enzyme complex(GO:0045239)
0.0 0.4 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 0.1 GO:0034464 BBSome(GO:0034464)
0.0 0.3 GO:0008023 transcription elongation factor complex(GO:0008023)
0.0 0.1 GO:0030992 intraciliary transport particle B(GO:0030992)
0.0 0.1 GO:0034451 centriolar satellite(GO:0034451)
0.0 0.1 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 0.1 GO:0008278 cohesin complex(GO:0008278)
0.0 0.1 GO:0005655 nucleolar ribonuclease P complex(GO:0005655) ribonuclease P complex(GO:0030677) multimeric ribonuclease P complex(GO:0030681)
0.0 0.1 GO:0005683 U7 snRNP(GO:0005683)
0.0 0.1 GO:0005958 DNA-dependent protein kinase-DNA ligase 4 complex(GO:0005958)
0.0 0.1 GO:0031205 endoplasmic reticulum Sec complex(GO:0031205)
0.0 0.6 GO:0016592 mediator complex(GO:0016592)
0.0 0.1 GO:0016461 unconventional myosin complex(GO:0016461)
0.0 0.1 GO:0098984 asymmetric synapse(GO:0032279) neuron to neuron synapse(GO:0098984)
0.0 0.1 GO:0031616 spindle pole centrosome(GO:0031616)
0.0 0.6 GO:0031970 organelle envelope lumen(GO:0031970)
0.0 0.4 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.0 0.0 GO:0000138 Golgi trans cisterna(GO:0000138)
0.0 0.1 GO:0005658 alpha DNA polymerase:primase complex(GO:0005658)
0.0 0.2 GO:0015030 Cajal body(GO:0015030)
0.0 0.4 GO:0043204 perikaryon(GO:0043204)
0.0 0.6 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.0 0.0 GO:0005863 striated muscle myosin thick filament(GO:0005863)
0.0 0.5 GO:0005876 spindle microtubule(GO:0005876)
0.0 0.1 GO:0014701 junctional sarcoplasmic reticulum membrane(GO:0014701)
0.0 0.0 GO:0035145 exon-exon junction complex(GO:0035145)
0.0 0.6 GO:0000794 condensed nuclear chromosome(GO:0000794)
0.0 1.0 GO:0000502 proteasome complex(GO:0000502)
0.0 0.3 GO:0005762 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.0 1.7 GO:0005681 spliceosomal complex(GO:0005681)
0.0 0.1 GO:0005883 neurofilament(GO:0005883)
0.0 1.0 GO:0001726 ruffle(GO:0001726)
0.0 1.2 GO:0032993 protein-DNA complex(GO:0032993)
0.0 0.0 GO:0042555 MCM complex(GO:0042555)
0.0 0.1 GO:0000930 gamma-tubulin complex(GO:0000930)
0.0 0.0 GO:0031228 intrinsic component of Golgi membrane(GO:0031228)
0.0 0.1 GO:0008180 COP9 signalosome(GO:0008180)
0.0 0.1 GO:0030288 outer membrane-bounded periplasmic space(GO:0030288) periplasmic space(GO:0042597)
0.0 1.4 GO:0005819 spindle(GO:0005819)
0.0 0.2 GO:0000781 chromosome, telomeric region(GO:0000781)
0.0 0.0 GO:1902555 endoribonuclease complex(GO:1902555)
0.0 0.4 GO:0042645 mitochondrial nucleoid(GO:0042645)
0.0 0.2 GO:0000228 nuclear chromosome(GO:0000228)
0.0 0.1 GO:0005849 mRNA cleavage factor complex(GO:0005849)
0.0 0.0 GO:0043596 nuclear replication fork(GO:0043596)
0.0 0.0 GO:0016533 cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533)
0.0 1.5 GO:0000785 chromatin(GO:0000785)
0.0 0.0 GO:0001741 XY body(GO:0001741)
0.0 0.0 GO:0000153 cytoplasmic ubiquitin ligase complex(GO:0000153)
0.0 0.9 GO:0016607 nuclear speck(GO:0016607)
0.0 0.1 GO:0045334 clathrin-coated endocytic vesicle(GO:0045334)
0.0 0.0 GO:0042583 chromaffin granule(GO:0042583) chromaffin granule membrane(GO:0042584)
0.0 0.0 GO:0072669 tRNA-splicing ligase complex(GO:0072669)
0.0 0.2 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)
0.0 0.1 GO:0000346 transcription export complex(GO:0000346)
0.0 0.7 GO:0005746 mitochondrial respiratory chain(GO:0005746)
0.0 0.0 GO:0042825 TAP complex(GO:0042825)
0.0 0.2 GO:0030119 AP-type membrane coat adaptor complex(GO:0030119)
0.0 0.0 GO:0045261 proton-transporting ATP synthase complex, catalytic core F(1)(GO:0045261)
0.0 0.2 GO:0005801 cis-Golgi network(GO:0005801)
0.0 0.3 GO:0005921 gap junction(GO:0005921)
0.0 0.0 GO:0034673 inhibin-betaglycan-ActRII complex(GO:0034673)
0.0 0.1 GO:0061202 clathrin-sculpted gamma-aminobutyric acid transport vesicle(GO:0061200) clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane(GO:0061202)
0.0 8.5 GO:0005730 nucleolus(GO:0005730)
0.0 0.2 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.0 0.0 GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.0 4.2 GO:0005654 nucleoplasm(GO:0005654)
0.0 0.0 GO:0005594 collagen type IX trimer(GO:0005594)
0.0 0.0 GO:0033270 paranode region of axon(GO:0033270)
0.0 0.0 GO:0017071 intracellular cyclic nucleotide activated cation channel complex(GO:0017071)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.8 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.2 0.7 GO:0016309 1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
0.2 0.7 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.2 2.9 GO:0004697 protein kinase C activity(GO:0004697)
0.2 0.5 GO:0047756 chondroitin 4-sulfotransferase activity(GO:0047756)
0.2 0.7 GO:0030284 estrogen receptor activity(GO:0030284)
0.2 0.8 GO:0046934 phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) phosphatidylinositol bisphosphate kinase activity(GO:0052813)
0.1 0.4 GO:0008545 JUN kinase kinase activity(GO:0008545)
0.1 0.4 GO:0015038 glutathione disulfide oxidoreductase activity(GO:0015038)
0.1 0.4 GO:0004911 interleukin-2 receptor activity(GO:0004911)
0.1 0.9 GO:0034713 type I transforming growth factor beta receptor binding(GO:0034713)
0.1 0.4 GO:0033691 sialic acid binding(GO:0033691)
0.1 2.5 GO:0001608 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.1 0.6 GO:0008266 poly(U) RNA binding(GO:0008266)
0.1 0.3 GO:0004311 farnesyltranstransferase activity(GO:0004311)
0.1 0.1 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.1 0.7 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.1 0.3 GO:0034236 protein kinase A catalytic subunit binding(GO:0034236)
0.1 0.3 GO:0016312 inositol bisphosphate phosphatase activity(GO:0016312)
0.1 0.1 GO:0001098 basal transcription machinery binding(GO:0001098) basal RNA polymerase II transcription machinery binding(GO:0001099)
0.1 0.3 GO:0003726 double-stranded RNA adenosine deaminase activity(GO:0003726)
0.1 0.4 GO:0015925 galactosidase activity(GO:0015925)
0.1 0.4 GO:0050815 phosphoserine binding(GO:0050815)
0.1 0.3 GO:0050265 RNA uridylyltransferase activity(GO:0050265)
0.1 0.9 GO:0016493 C-C chemokine receptor activity(GO:0016493)
0.1 0.4 GO:0004904 interferon receptor activity(GO:0004904)
0.1 0.3 GO:0004465 lipoprotein lipase activity(GO:0004465)
0.1 1.0 GO:0070412 R-SMAD binding(GO:0070412)
0.1 0.4 GO:0016004 phospholipase activator activity(GO:0016004)
0.1 0.3 GO:0034237 protein kinase A regulatory subunit binding(GO:0034237)
0.1 0.3 GO:0005025 transforming growth factor beta receptor activity, type I(GO:0005025)
0.1 0.8 GO:0034593 phosphatidylinositol bisphosphate phosphatase activity(GO:0034593)
0.1 0.8 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.1 0.5 GO:0035004 1-phosphatidylinositol-3-kinase activity(GO:0016303) phosphatidylinositol 3-kinase activity(GO:0035004)
0.1 0.2 GO:0030375 thyroid hormone receptor coactivator activity(GO:0030375)
0.1 0.2 GO:0000339 RNA cap binding(GO:0000339)
0.1 0.3 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.1 0.2 GO:0004999 vasoactive intestinal polypeptide receptor activity(GO:0004999)
0.1 0.4 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.1 0.7 GO:0004579 dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.1 0.2 GO:0004566 beta-glucuronidase activity(GO:0004566)
0.1 0.6 GO:0003785 actin monomer binding(GO:0003785)
0.1 0.2 GO:0005113 patched binding(GO:0005113)
0.1 0.3 GO:0047238 glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity(GO:0047238)
0.1 0.2 GO:0098599 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.1 0.3 GO:0043495 protein anchor(GO:0043495)
0.1 0.2 GO:0005176 ErbB-2 class receptor binding(GO:0005176)
0.1 0.6 GO:0015385 sodium:proton antiporter activity(GO:0015385)
0.1 0.2 GO:0042156 obsolete zinc-mediated transcriptional activator activity(GO:0042156)
0.1 0.2 GO:0005127 ciliary neurotrophic factor receptor binding(GO:0005127)
0.1 0.3 GO:0019788 NEDD8 transferase activity(GO:0019788)
0.1 0.3 GO:0030235 nitric-oxide synthase regulator activity(GO:0030235)
0.1 0.2 GO:0004949 cannabinoid receptor activity(GO:0004949)
0.1 0.3 GO:0005131 growth hormone receptor binding(GO:0005131)
0.1 0.2 GO:0016149 translation release factor activity, codon specific(GO:0016149)
0.1 0.5 GO:0031419 cobalamin binding(GO:0031419)
0.1 1.0 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.1 0.4 GO:0051766 inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440) inositol trisphosphate kinase activity(GO:0051766)
0.1 0.1 GO:0008179 adenylate cyclase binding(GO:0008179)
0.1 0.3 GO:0008296 3'-5'-exodeoxyribonuclease activity(GO:0008296)
0.1 0.1 GO:0003724 RNA helicase activity(GO:0003724)
0.1 0.6 GO:0016274 arginine N-methyltransferase activity(GO:0016273) protein-arginine N-methyltransferase activity(GO:0016274)
0.1 0.5 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.1 0.8 GO:0005095 GTPase inhibitor activity(GO:0005095)
0.1 0.4 GO:0016778 diphosphotransferase activity(GO:0016778)
0.1 0.4 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.1 0.2 GO:0042910 xenobiotic-transporting ATPase activity(GO:0008559) xenobiotic transporter activity(GO:0042910)
0.1 0.9 GO:0030159 receptor signaling complex scaffold activity(GO:0030159)
0.1 0.3 GO:0004396 hexokinase activity(GO:0004396)
0.1 0.4 GO:0030332 cyclin binding(GO:0030332)
0.1 0.2 GO:0003910 DNA ligase activity(GO:0003909) DNA ligase (ATP) activity(GO:0003910)
0.1 1.7 GO:0003725 double-stranded RNA binding(GO:0003725)
0.1 1.0 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.1 0.4 GO:0008494 translation activator activity(GO:0008494)
0.1 0.2 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
0.1 0.2 GO:0030292 protein tyrosine kinase inhibitor activity(GO:0030292)
0.1 0.3 GO:0016494 C-X-C chemokine receptor activity(GO:0016494)
0.1 0.3 GO:0051018 protein kinase A binding(GO:0051018)
0.1 0.3 GO:0051400 BH domain binding(GO:0051400)
0.1 0.2 GO:0004875 complement receptor activity(GO:0004875)
0.1 0.4 GO:0015278 calcium-release channel activity(GO:0015278) ligand-gated calcium channel activity(GO:0099604)
0.1 0.2 GO:0004591 oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591)
0.1 0.2 GO:0004607 phosphatidylcholine-sterol O-acyltransferase activity(GO:0004607)
0.1 0.4 GO:0015271 outward rectifier potassium channel activity(GO:0015271)
0.1 0.3 GO:0050733 RS domain binding(GO:0050733)
0.1 1.0 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.1 0.7 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.1 0.3 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.1 0.1 GO:0035197 siRNA binding(GO:0035197)
0.1 0.5 GO:0008536 Ran GTPase binding(GO:0008536)
0.1 0.1 GO:0000268 peroxisome targeting sequence binding(GO:0000268)
0.1 0.2 GO:0005134 interleukin-2 receptor binding(GO:0005134)
0.0 0.1 GO:0019166 trans-2-enoyl-CoA reductase (NADPH) activity(GO:0019166)
0.0 0.3 GO:0070087 chromo shadow domain binding(GO:0070087)
0.0 0.1 GO:0003829 beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity(GO:0003829)
0.0 0.5 GO:0004659 prenyltransferase activity(GO:0004659)
0.0 0.0 GO:0016896 exoribonuclease activity, producing 5'-phosphomonoesters(GO:0016896)
0.0 0.1 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.0 1.7 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.0 0.3 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.0 0.3 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0 0.1 GO:0061731 ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
0.0 0.0 GO:0000400 four-way junction DNA binding(GO:0000400)
0.0 0.2 GO:0035252 UDP-xylosyltransferase activity(GO:0035252) xylosyltransferase activity(GO:0042285)
0.0 0.4 GO:0030276 clathrin binding(GO:0030276)
0.0 0.3 GO:0004126 cytidine deaminase activity(GO:0004126)
0.0 0.1 GO:0003953 NAD+ nucleosidase activity(GO:0003953)
0.0 0.1 GO:0032139 dinucleotide insertion or deletion binding(GO:0032139)
0.0 0.3 GO:0015165 pyrimidine nucleotide-sugar transmembrane transporter activity(GO:0015165)
0.0 0.1 GO:0000064 L-ornithine transmembrane transporter activity(GO:0000064)
0.0 0.2 GO:0009374 biotin binding(GO:0009374)
0.0 0.1 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.0 0.1 GO:0051734 ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity(GO:0046404) polydeoxyribonucleotide kinase activity(GO:0051733) ATP-dependent polynucleotide kinase activity(GO:0051734)
0.0 0.1 GO:0048185 activin binding(GO:0048185)
0.0 0.3 GO:0003857 3-hydroxyacyl-CoA dehydrogenase activity(GO:0003857)
0.0 0.2 GO:0031996 thioesterase binding(GO:0031996)
0.0 0.1 GO:0098847 single-stranded telomeric DNA binding(GO:0043047) sequence-specific single stranded DNA binding(GO:0098847)
0.0 1.0 GO:0019003 GDP binding(GO:0019003)
0.0 0.3 GO:0070567 cytidylyltransferase activity(GO:0070567)
0.0 0.2 GO:0004127 cytidylate kinase activity(GO:0004127)
0.0 0.1 GO:0004706 JUN kinase kinase kinase activity(GO:0004706)
0.0 0.2 GO:0061505 DNA topoisomerase type II (ATP-hydrolyzing) activity(GO:0003918) DNA topoisomerase II activity(GO:0061505)
0.0 0.2 GO:0003988 acetyl-CoA C-acyltransferase activity(GO:0003988)
0.0 0.1 GO:0004719 protein-L-isoaspartate (D-aspartate) O-methyltransferase activity(GO:0004719)
0.0 0.5 GO:0031593 polyubiquitin binding(GO:0031593)
0.0 1.4 GO:0101005 thiol-dependent ubiquitin-specific protease activity(GO:0004843) thiol-dependent ubiquitinyl hydrolase activity(GO:0036459) ubiquitinyl hydrolase activity(GO:0101005)
0.0 0.1 GO:0032554 purine deoxyribonucleotide binding(GO:0032554) adenyl deoxyribonucleotide binding(GO:0032558)
0.0 0.2 GO:0005381 iron ion transmembrane transporter activity(GO:0005381)
0.0 0.0 GO:0008821 crossover junction endodeoxyribonuclease activity(GO:0008821)
0.0 0.1 GO:0060230 lipoprotein lipase activator activity(GO:0060230)
0.0 0.1 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.0 0.5 GO:0005344 oxygen transporter activity(GO:0005344)
0.0 0.1 GO:0070579 methylcytosine dioxygenase activity(GO:0070579)
0.0 0.2 GO:0031210 phosphatidylcholine binding(GO:0031210)
0.0 0.2 GO:0031702 type 1 angiotensin receptor binding(GO:0031702)
0.0 0.4 GO:0005416 cation:amino acid symporter activity(GO:0005416)
0.0 0.2 GO:0015288 porin activity(GO:0015288)
0.0 0.4 GO:0016888 endodeoxyribonuclease activity, producing 5'-phosphomonoesters(GO:0016888)
0.0 0.1 GO:0015254 glycerol channel activity(GO:0015254)
0.0 0.2 GO:0004703 G-protein coupled receptor kinase activity(GO:0004703)
0.0 0.5 GO:0019534 toxin transporter activity(GO:0019534)
0.0 0.1 GO:0030976 thiamine pyrophosphate binding(GO:0030976)
0.0 0.3 GO:0042162 telomeric DNA binding(GO:0042162)
0.0 0.5 GO:0008353 RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.0 0.1 GO:0008409 5'-3' exonuclease activity(GO:0008409)
0.0 0.3 GO:0004551 nucleotide diphosphatase activity(GO:0004551)
0.0 0.2 GO:0015355 secondary active monocarboxylate transmembrane transporter activity(GO:0015355)
0.0 0.1 GO:0048156 tau protein binding(GO:0048156)
0.0 0.1 GO:0071723 lipopeptide binding(GO:0071723)
0.0 0.1 GO:0003945 N-acetyllactosamine synthase activity(GO:0003945)
0.0 0.5 GO:0001540 beta-amyloid binding(GO:0001540)
0.0 2.1 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.0 0.1 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
0.0 0.1 GO:0016997 exo-alpha-sialidase activity(GO:0004308) alpha-sialidase activity(GO:0016997)
0.0 0.1 GO:0033300 dehydroascorbic acid transporter activity(GO:0033300)
0.0 0.9 GO:0003823 antigen binding(GO:0003823)
0.0 0.2 GO:0046974 histone methyltransferase activity (H3-K9 specific)(GO:0046974)
0.0 0.1 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.0 0.1 GO:0015924 mannosyl-oligosaccharide mannosidase activity(GO:0015924)
0.0 0.2 GO:0017176 phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.0 0.1 GO:0005105 type 1 fibroblast growth factor receptor binding(GO:0005105)
0.0 1.0 GO:0003755 peptidyl-prolyl cis-trans isomerase activity(GO:0003755)
0.0 0.2 GO:0019789 SUMO transferase activity(GO:0019789)
0.0 0.2 GO:0015232 heme transporter activity(GO:0015232)
0.0 0.2 GO:0004704 NF-kappaB-inducing kinase activity(GO:0004704)
0.0 0.1 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454)
0.0 0.2 GO:0016565 obsolete general transcriptional repressor activity(GO:0016565)
0.0 0.2 GO:0048487 beta-tubulin binding(GO:0048487)
0.0 0.2 GO:0031013 troponin I binding(GO:0031013)
0.0 1.6 GO:0008301 DNA binding, bending(GO:0008301)
0.0 0.2 GO:0016520 growth hormone-releasing hormone receptor activity(GO:0016520)
0.0 0.1 GO:0016972 thiol oxidase activity(GO:0016972)
0.0 0.1 GO:0004449 isocitrate dehydrogenase (NAD+) activity(GO:0004449)
0.0 0.4 GO:0042287 MHC protein binding(GO:0042287)
0.0 0.4 GO:0016864 protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864)
0.0 0.1 GO:0070548 L-glutamine aminotransferase activity(GO:0070548)
0.0 0.1 GO:0031685 adenosine receptor binding(GO:0031685)
0.0 0.3 GO:0016922 ligand-dependent nuclear receptor binding(GO:0016922)
0.0 0.1 GO:0017025 TBP-class protein binding(GO:0017025)
0.0 0.0 GO:0000403 Y-form DNA binding(GO:0000403)
0.0 0.6 GO:0008373 sialyltransferase activity(GO:0008373)
0.0 0.1 GO:0004886 9-cis retinoic acid receptor activity(GO:0004886)
0.0 0.6 GO:0051219 phosphoprotein binding(GO:0051219)
0.0 0.4 GO:0016805 dipeptidase activity(GO:0016805)
0.0 0.1 GO:0004784 superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
0.0 0.1 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.0 0.1 GO:0008175 tRNA methyltransferase activity(GO:0008175)
0.0 0.1 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.0 0.1 GO:0031701 angiotensin receptor binding(GO:0031701)
0.0 0.1 GO:0004045 aminoacyl-tRNA hydrolase activity(GO:0004045)
0.0 0.7 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.0 0.1 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.0 0.2 GO:0008499 UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity(GO:0008499)
0.0 0.0 GO:0051731 polynucleotide 5'-hydroxyl-kinase activity(GO:0051731)
0.0 0.1 GO:0005087 Ran guanyl-nucleotide exchange factor activity(GO:0005087)
0.0 0.9 GO:0004402 histone acetyltransferase activity(GO:0004402)
0.0 0.1 GO:0000247 C-8 sterol isomerase activity(GO:0000247)
0.0 0.7 GO:0004003 ATP-dependent DNA helicase activity(GO:0004003)
0.0 0.1 GO:0001848 complement binding(GO:0001848)
0.0 0.1 GO:0008079 translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079)
0.0 0.1 GO:0004064 arylesterase activity(GO:0004064)
0.0 0.0 GO:0070653 high-density lipoprotein particle receptor binding(GO:0070653)
0.0 0.3 GO:0019894 kinesin binding(GO:0019894)
0.0 0.1 GO:0019136 deoxynucleoside kinase activity(GO:0019136)
0.0 1.0 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)
0.0 1.3 GO:0004197 cysteine-type endopeptidase activity(GO:0004197)
0.0 0.1 GO:0001609 G-protein coupled adenosine receptor activity(GO:0001609)
0.0 0.2 GO:0035251 UDP-glucosyltransferase activity(GO:0035251)
0.0 0.1 GO:0008073 ornithine decarboxylase inhibitor activity(GO:0008073)
0.0 0.1 GO:0090079 translation regulator activity, nucleic acid binding(GO:0090079)
0.0 0.1 GO:0005092 GDP-dissociation inhibitor activity(GO:0005092)
0.0 0.4 GO:0004889 acetylcholine-activated cation-selective channel activity(GO:0004889)
0.0 0.3 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 0.1 GO:0004802 transketolase activity(GO:0004802)
0.0 0.1 GO:0003847 1-alkyl-2-acetylglycerophosphocholine esterase activity(GO:0003847)
0.0 0.1 GO:0016986 obsolete transcription initiation factor activity(GO:0016986)
0.0 0.1 GO:0016842 amidine-lyase activity(GO:0016842)
0.0 0.1 GO:0005521 lamin binding(GO:0005521)
0.0 0.1 GO:0008159 obsolete positive transcription elongation factor activity(GO:0008159)
0.0 0.1 GO:0043024 ribosomal small subunit binding(GO:0043024)
0.0 0.0 GO:0070410 co-SMAD binding(GO:0070410)
0.0 0.1 GO:0003701 obsolete RNA polymerase I transcription factor activity(GO:0003701)
0.0 0.1 GO:0008526 phosphatidylinositol transporter activity(GO:0008526)
0.0 0.1 GO:0016941 natriuretic peptide receptor activity(GO:0016941)
0.0 0.3 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0 0.1 GO:0050508 glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0050508)
0.0 0.2 GO:0008158 hedgehog receptor activity(GO:0008158)
0.0 0.6 GO:0005080 protein kinase C binding(GO:0005080)
0.0 0.0 GO:0008853 exodeoxyribonuclease III activity(GO:0008853)
0.0 0.1 GO:0004966 galanin receptor activity(GO:0004966)
0.0 0.1 GO:0015379 potassium:chloride symporter activity(GO:0015379)
0.0 0.2 GO:0004022 alcohol dehydrogenase (NAD) activity(GO:0004022)
0.0 0.2 GO:0017075 syntaxin-1 binding(GO:0017075)
0.0 0.1 GO:0004111 creatine kinase activity(GO:0004111)
0.0 0.0 GO:0042054 histone methyltransferase activity(GO:0042054)
0.0 0.1 GO:0005114 type II transforming growth factor beta receptor binding(GO:0005114)
0.0 0.1 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.0 0.1 GO:0015216 adenine nucleotide transmembrane transporter activity(GO:0000295) purine nucleotide transmembrane transporter activity(GO:0015216)
0.0 0.0 GO:0001846 opsonin binding(GO:0001846)
0.0 0.1 GO:0004957 prostaglandin E receptor activity(GO:0004957)
0.0 0.1 GO:0004594 pantothenate kinase activity(GO:0004594)
0.0 0.5 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.0 0.1 GO:0097506 uracil DNA N-glycosylase activity(GO:0004844) deaminated base DNA N-glycosylase activity(GO:0097506)
0.0 0.7 GO:0003697 single-stranded DNA binding(GO:0003697)
0.0 0.3 GO:0004016 adenylate cyclase activity(GO:0004016)
0.0 0.3 GO:0005031 tumor necrosis factor-activated receptor activity(GO:0005031)
0.0 0.1 GO:0015347 sodium-independent organic anion transmembrane transporter activity(GO:0015347)
0.0 0.1 GO:0032947 protein complex scaffold(GO:0032947)
0.0 0.1 GO:0016944 obsolete RNA polymerase II transcription elongation factor activity(GO:0016944)
0.0 0.2 GO:0070491 repressing transcription factor binding(GO:0070491)
0.0 0.3 GO:0016505 peptidase activator activity involved in apoptotic process(GO:0016505)
0.0 0.1 GO:0004062 aryl sulfotransferase activity(GO:0004062)
0.0 0.0 GO:0019956 chemokine binding(GO:0019956)
0.0 0.5 GO:0001104 RNA polymerase II transcription cofactor activity(GO:0001104)
0.0 0.1 GO:0050700 CARD domain binding(GO:0050700)
0.0 0.4 GO:0015002 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors(GO:0016675) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 0.9 GO:0042393 histone binding(GO:0042393)
0.0 0.2 GO:0015026 coreceptor activity(GO:0015026)
0.0 0.1 GO:0042392 sphingosine-1-phosphate phosphatase activity(GO:0042392)
0.0 0.5 GO:0004177 aminopeptidase activity(GO:0004177)
0.0 0.2 GO:0043621 protein self-association(GO:0043621)
0.0 0.1 GO:0051019 mitogen-activated protein kinase binding(GO:0051019)
0.0 0.1 GO:0004427 inorganic diphosphatase activity(GO:0004427)
0.0 0.1 GO:0017080 sodium channel regulator activity(GO:0017080)
0.0 0.1 GO:0008967 phosphoglycolate phosphatase activity(GO:0008967)
0.0 0.2 GO:0017091 AU-rich element binding(GO:0017091)
0.0 0.4 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 1.0 GO:0044389 ubiquitin protein ligase binding(GO:0031625) ubiquitin-like protein ligase binding(GO:0044389)
0.0 0.5 GO:0008080 N-acetyltransferase activity(GO:0008080)
0.0 0.8 GO:0051015 actin filament binding(GO:0051015)
0.0 0.2 GO:0010181 FMN binding(GO:0010181)
0.0 0.2 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.0 0.0 GO:0005528 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.0 0.1 GO:0008195 phosphatidate phosphatase activity(GO:0008195)
0.0 0.9 GO:0003743 translation initiation factor activity(GO:0003743)
0.0 0.0 GO:0050510 N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity(GO:0050510)
0.0 0.1 GO:0005152 interleukin-1 receptor antagonist activity(GO:0005152)
0.0 0.1 GO:0043130 ubiquitin binding(GO:0043130)
0.0 0.2 GO:0043014 alpha-tubulin binding(GO:0043014)
0.0 0.1 GO:0070643 vitamin D3 25-hydroxylase activity(GO:0030343) vitamin D 25-hydroxylase activity(GO:0070643)
0.0 0.1 GO:0004568 chitinase activity(GO:0004568)
0.0 0.1 GO:0005315 inorganic phosphate transmembrane transporter activity(GO:0005315)
0.0 0.7 GO:0019829 cation-transporting ATPase activity(GO:0019829)
0.0 0.1 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.0 0.1 GO:0016748 succinyltransferase activity(GO:0016748)
0.0 0.1 GO:0003688 DNA replication origin binding(GO:0003688)
0.0 0.0 GO:0016361 activin receptor activity, type I(GO:0016361)
0.0 0.1 GO:0046923 ER retention sequence binding(GO:0046923)
0.0 0.3 GO:0008186 RNA-dependent ATPase activity(GO:0008186)
0.0 0.1 GO:0017049 GTP-Rho binding(GO:0017049)
0.0 0.2 GO:0008430 selenium binding(GO:0008430)
0.0 0.0 GO:0019959 C-X-C chemokine binding(GO:0019958) interleukin-8 binding(GO:0019959)
0.0 5.4 GO:0004674 protein serine/threonine kinase activity(GO:0004674)
0.0 0.2 GO:0005487 nucleocytoplasmic transporter activity(GO:0005487)
0.0 0.4 GO:0019843 rRNA binding(GO:0019843)
0.0 0.1 GO:0015205 nucleobase transmembrane transporter activity(GO:0015205)
0.0 0.4 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.0 0.5 GO:0004221 obsolete ubiquitin thiolesterase activity(GO:0004221)
0.0 0.1 GO:0016857 racemase and epimerase activity, acting on carbohydrates and derivatives(GO:0016857)
0.0 0.0 GO:0008332 low voltage-gated calcium channel activity(GO:0008332)
0.0 0.0 GO:0042808 obsolete neuronal Cdc2-like kinase binding(GO:0042808)
0.0 0.0 GO:0017159 pantetheine hydrolase activity(GO:0017159)
0.0 0.0 GO:0017060 3-galactosyl-N-acetylglucosaminide 4-alpha-L-fucosyltransferase activity(GO:0017060)
0.0 0.0 GO:0042806 fucose binding(GO:0042806)
0.0 0.0 GO:0031014 troponin T binding(GO:0031014)
0.0 0.0 GO:0015321 sodium-dependent phosphate transmembrane transporter activity(GO:0015321)
0.0 0.1 GO:0042043 neurexin family protein binding(GO:0042043)
0.0 0.0 GO:0030881 beta-2-microglobulin binding(GO:0030881)
0.0 0.2 GO:0042301 phosphate ion binding(GO:0042301)
0.0 0.1 GO:0008889 glycerophosphodiester phosphodiesterase activity(GO:0008889)
0.0 0.0 GO:0019237 centromeric DNA binding(GO:0019237)
0.0 0.1 GO:0005007 fibroblast growth factor-activated receptor activity(GO:0005007)
0.0 0.1 GO:0001727 lipid kinase activity(GO:0001727)
0.0 0.0 GO:0004075 biotin carboxylase activity(GO:0004075)
0.0 0.7 GO:0003690 double-stranded DNA binding(GO:0003690)
0.0 0.1 GO:0008486 diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486)
0.0 1.5 GO:0003702 obsolete RNA polymerase II transcription factor activity(GO:0003702)
0.0 0.1 GO:0031432 titin binding(GO:0031432)
0.0 0.2 GO:0008484 sulfuric ester hydrolase activity(GO:0008484)
0.0 0.1 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.0 0.0 GO:0043008 ATP-dependent protein binding(GO:0043008)
0.0 0.1 GO:0008171 O-methyltransferase activity(GO:0008171)
0.0 0.1 GO:0015252 hydrogen ion channel activity(GO:0015252)
0.0 0.5 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.0 0.1 GO:0016634 oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor(GO:0016634)
0.0 0.1 GO:0043022 ribosome binding(GO:0043022)
0.0 0.1 GO:0004047 aminomethyltransferase activity(GO:0004047)
0.0 0.1 GO:0016406 carnitine O-acyltransferase activity(GO:0016406)
0.0 0.1 GO:0016307 phosphatidylinositol phosphate kinase activity(GO:0016307)
0.0 0.1 GO:0004983 neuropeptide Y receptor activity(GO:0004983)
0.0 0.1 GO:0004950 G-protein coupled chemoattractant receptor activity(GO:0001637) chemokine receptor activity(GO:0004950)
0.0 0.0 GO:0019797 procollagen-proline 3-dioxygenase activity(GO:0019797) peptidyl-proline 3-dioxygenase activity(GO:0031544)
0.0 0.1 GO:1901677 phosphate transmembrane transporter activity(GO:1901677)
0.0 0.1 GO:0046875 ephrin receptor binding(GO:0046875)
0.0 0.2 GO:0000155 phosphorelay sensor kinase activity(GO:0000155)
0.0 0.1 GO:0004559 alpha-mannosidase activity(GO:0004559)
0.0 0.0 GO:0000033 alpha-1,3-mannosyltransferase activity(GO:0000033)
0.0 0.1 GO:0001517 N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517)
0.0 0.0 GO:0004448 isocitrate dehydrogenase activity(GO:0004448)
0.0 0.7 GO:0008026 ATP-dependent helicase activity(GO:0008026) purine NTP-dependent helicase activity(GO:0070035)
0.0 0.0 GO:0004351 glutamate decarboxylase activity(GO:0004351)
0.0 0.0 GO:0004563 beta-N-acetylhexosaminidase activity(GO:0004563)
0.0 0.0 GO:0016882 cyclo-ligase activity(GO:0016882)
0.0 0.0 GO:0004167 dopachrome isomerase activity(GO:0004167)
0.0 0.1 GO:0004887 thyroid hormone receptor activity(GO:0004887)
0.0 0.0 GO:0008192 RNA guanylyltransferase activity(GO:0008192)
0.0 0.1 GO:0015057 thrombin receptor activity(GO:0015057)
0.0 0.0 GO:0004828 serine-tRNA ligase activity(GO:0004828)
0.0 0.2 GO:0016891 endoribonuclease activity, producing 5'-phosphomonoesters(GO:0016891)
0.0 0.2 GO:0016780 phosphotransferase activity, for other substituted phosphate groups(GO:0016780)
0.0 0.0 GO:0031491 nucleosome binding(GO:0031491)
0.0 0.1 GO:0016861 intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861)
0.0 0.1 GO:0016668 oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor(GO:0016668)
0.0 0.0 GO:0050220 prostaglandin-E synthase activity(GO:0050220)
0.0 0.0 GO:0003896 DNA primase activity(GO:0003896)
0.0 0.0 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
0.0 0.1 GO:0005452 inorganic anion exchanger activity(GO:0005452)
0.0 0.1 GO:0035586 purinergic receptor activity(GO:0035586)
0.0 0.0 GO:0034594 phosphatidylinositol trisphosphate phosphatase activity(GO:0034594)
0.0 0.2 GO:0003995 acyl-CoA dehydrogenase activity(GO:0003995)
0.0 0.0 GO:0005035 death receptor activity(GO:0005035)
0.0 0.1 GO:0043499 obsolete eukaryotic cell surface binding(GO:0043499)
0.0 0.0 GO:0016175 superoxide-generating NADPH oxidase activity(GO:0016175)
0.0 0.0 GO:0030492 hemoglobin binding(GO:0030492)
0.0 0.1 GO:0032393 MHC class I receptor activity(GO:0032393)
0.0 0.0 GO:0042166 acetylcholine binding(GO:0042166)
0.0 0.0 GO:0031708 bombesin receptor binding(GO:0031705) endothelin B receptor binding(GO:0031708)
0.0 0.0 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.0 0.1 GO:0004652 polynucleotide adenylyltransferase activity(GO:0004652)
0.0 0.1 GO:0005328 neurotransmitter:sodium symporter activity(GO:0005328)
0.0 0.0 GO:0003987 acetate-CoA ligase activity(GO:0003987)
0.0 0.1 GO:0005221 intracellular cyclic nucleotide activated cation channel activity(GO:0005221) cyclic nucleotide-gated ion channel activity(GO:0043855)
0.0 0.0 GO:0015142 citrate transmembrane transporter activity(GO:0015137) tricarboxylic acid transmembrane transporter activity(GO:0015142)
0.0 0.0 GO:0017162 aryl hydrocarbon receptor binding(GO:0017162)
0.0 0.1 GO:0004602 glutathione peroxidase activity(GO:0004602)
0.0 0.4 GO:0008170 N-methyltransferase activity(GO:0008170)
0.0 0.0 GO:0004985 opioid receptor activity(GO:0004985)
0.0 0.8 GO:0017124 SH3 domain binding(GO:0017124)
0.0 0.0 GO:0004000 adenosine deaminase activity(GO:0004000)
0.0 0.3 GO:0004386 helicase activity(GO:0004386)
0.0 0.0 GO:0048018 receptor agonist activity(GO:0048018)
0.0 0.2 GO:0005484 SNAP receptor activity(GO:0005484)
0.0 0.2 GO:0000049 tRNA binding(GO:0000049)
0.0 0.0 GO:0003916 DNA topoisomerase activity(GO:0003916)
0.0 0.0 GO:0050698 proteoglycan sulfotransferase activity(GO:0050698)
0.0 0.2 GO:0033764 steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor(GO:0033764)
0.0 0.1 GO:0016860 intramolecular oxidoreductase activity(GO:0016860)
0.0 0.4 GO:0003954 NADH dehydrogenase activity(GO:0003954) NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0 4.7 GO:0003723 RNA binding(GO:0003723)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 7.3 PID CD8 TCR PATHWAY TCR signaling in naïve CD8+ T cells
0.1 1.5 SA PTEN PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.1 1.7 PID TCR PATHWAY TCR signaling in naïve CD4+ T cells
0.1 1.7 SIG IL4RECEPTOR IN B LYPHOCYTES Genes related to IL4 rceptor signaling in B lymphocytes
0.1 0.1 PID PI3KCI AKT PATHWAY Class I PI3K signaling events mediated by Akt
0.1 1.3 PID BETA CATENIN DEG PATHWAY Degradation of beta catenin
0.1 1.1 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.1 1.0 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4
0.1 1.0 ST PHOSPHOINOSITIDE 3 KINASE PATHWAY PI3K Pathway
0.1 2.9 PID NFAT 3PATHWAY Role of Calcineurin-dependent NFAT signaling in lymphocytes
0.1 0.7 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.1 1.5 PID EPHRINB REV PATHWAY Ephrin B reverse signaling
0.1 0.4 PID RANBP2 PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.1 1.4 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.1 0.4 PID GMCSF PATHWAY GMCSF-mediated signaling events
0.1 0.8 PID IL2 STAT5 PATHWAY IL2 signaling events mediated by STAT5
0.1 2.2 PID TNF PATHWAY TNF receptor signaling pathway
0.1 0.6 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.1 1.3 PID IL8 CXCR2 PATHWAY IL8- and CXCR2-mediated signaling events
0.0 0.2 PID IL5 PATHWAY IL5-mediated signaling events
0.0 0.7 PID P38 ALPHA BETA PATHWAY Regulation of p38-alpha and p38-beta
0.0 1.2 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.0 0.8 PID MYC PATHWAY C-MYC pathway
0.0 0.6 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.0 0.0 PID TCR JNK PATHWAY JNK signaling in the CD4+ TCR pathway
0.0 0.8 PID BCR 5PATHWAY BCR signaling pathway
0.0 0.3 SA CASPASE CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.0 0.5 PID IL2 1PATHWAY IL2-mediated signaling events
0.0 0.6 PID IFNG PATHWAY IFN-gamma pathway
0.0 1.1 PID AR TF PATHWAY Regulation of Androgen receptor activity
0.0 0.0 ST TUMOR NECROSIS FACTOR PATHWAY Tumor Necrosis Factor Pathway.
0.0 1.3 PID P53 REGULATION PATHWAY p53 pathway
0.0 0.4 PID HIV NEF PATHWAY HIV-1 Nef: Negative effector of Fas and TNF-alpha
0.0 0.0 ST GRANULE CELL SURVIVAL PATHWAY Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway.
0.0 0.0 PID LYMPH ANGIOGENESIS PATHWAY VEGFR3 signaling in lymphatic endothelium
0.0 0.2 PID IL2 PI3K PATHWAY IL2 signaling events mediated by PI3K
0.0 0.2 PID WNT CANONICAL PATHWAY Canonical Wnt signaling pathway
0.0 0.7 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.0 0.6 PID ALK1 PATHWAY ALK1 signaling events
0.0 0.2 PID TRAIL PATHWAY TRAIL signaling pathway
0.0 0.1 ST JAK STAT PATHWAY Jak-STAT Pathway
0.0 0.4 PID LPA4 PATHWAY LPA4-mediated signaling events
0.0 1.0 PID LKB1 PATHWAY LKB1 signaling events
0.0 0.3 SIG BCR SIGNALING PATHWAY Members of the BCR signaling pathway
0.0 0.2 PID INTEGRIN3 PATHWAY Beta3 integrin cell surface interactions
0.0 0.5 SIG CD40PATHWAYMAP Genes related to CD40 signaling
0.0 0.2 ST B CELL ANTIGEN RECEPTOR B Cell Antigen Receptor
0.0 0.5 PID PI3KCI PATHWAY Class I PI3K signaling events
0.0 1.0 PID PLK1 PATHWAY PLK1 signaling events
0.0 0.2 PID DNA PK PATHWAY DNA-PK pathway in nonhomologous end joining
0.0 0.6 PID MTOR 4PATHWAY mTOR signaling pathway
0.0 0.3 PID CERAMIDE PATHWAY Ceramide signaling pathway
0.0 0.1 ST TYPE I INTERFERON PATHWAY Type I Interferon (alpha/beta IFN) Pathway
0.0 0.3 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL
0.0 0.4 PID ERBB1 INTERNALIZATION PATHWAY Internalization of ErbB1
0.0 0.1 PID FAS PATHWAY FAS (CD95) signaling pathway
0.0 0.2 SIG INSULIN RECEPTOR PATHWAY IN CARDIAC MYOCYTES Genes related to the insulin receptor pathway
0.0 0.0 SA B CELL RECEPTOR COMPLEXES Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.0 0.0 PID CXCR3 PATHWAY CXCR3-mediated signaling events
0.0 0.1 ST JNK MAPK PATHWAY JNK MAPK Pathway
0.0 0.0 PID NFKAPPAB ATYPICAL PATHWAY Atypical NF-kappaB pathway
0.0 0.1 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.0 0.0 ST DIFFERENTIATION PATHWAY IN PC12 CELLS Differentiation Pathway in PC12 Cells; this is a specific case of PAC1 Receptor Pathway.
0.0 0.6 PID RAC1 PATHWAY RAC1 signaling pathway
0.0 0.3 PID HIF1A PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.0 0.1 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.0 0.2 PID S1P S1P1 PATHWAY S1P1 pathway
0.0 0.1 PID MAPK TRK PATHWAY Trk receptor signaling mediated by the MAPK pathway
0.0 0.1 PID PS1 PATHWAY Presenilin action in Notch and Wnt signaling
0.0 0.7 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 0.5 PID HEDGEHOG GLI PATHWAY Hedgehog signaling events mediated by Gli proteins
0.0 0.2 PID CDC42 PATHWAY CDC42 signaling events
0.0 0.4 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.0 0.0 PID ERBB1 RECEPTOR PROXIMAL PATHWAY EGF receptor (ErbB1) signaling pathway
0.0 0.1 PID IL27 PATHWAY IL27-mediated signaling events
0.0 0.4 PID CXCR4 PATHWAY CXCR4-mediated signaling events
0.0 0.1 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.0 0.4 PID ATM PATHWAY ATM pathway
0.0 0.4 PID IL4 2PATHWAY IL4-mediated signaling events
0.0 0.2 PID RHOA PATHWAY RhoA signaling pathway
0.0 0.1 PID RET PATHWAY Signaling events regulated by Ret tyrosine kinase
0.0 0.1 SIG PIP3 SIGNALING IN B LYMPHOCYTES Genes related to PIP3 signaling in B lymphocytes
0.0 0.3 PID HDAC CLASSI PATHWAY Signaling events mediated by HDAC Class I
0.0 0.0 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.0 0.0 PID ALK2 PATHWAY ALK2 signaling events
0.0 0.3 PID RHOA REG PATHWAY Regulation of RhoA activity
0.0 0.5 PID CMYB PATHWAY C-MYB transcription factor network
0.0 0.2 PID ARF6 PATHWAY Arf6 signaling events
0.0 0.0 ST G ALPHA S PATHWAY G alpha s Pathway
0.0 0.0 ST PAC1 RECEPTOR PATHWAY PAC1 Receptor Pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.2 0.2 REACTOME AUTODEGRADATION OF THE E3 UBIQUITIN LIGASE COP1 Genes involved in Autodegradation of the E3 ubiquitin ligase COP1
0.1 1.6 REACTOME CD28 DEPENDENT VAV1 PATHWAY Genes involved in CD28 dependent Vav1 pathway
0.1 3.0 REACTOME GENERATION OF SECOND MESSENGER MOLECULES Genes involved in Generation of second messenger molecules
0.1 0.1 REACTOME DESTABILIZATION OF MRNA BY BRF1 Genes involved in Destabilization of mRNA by Butyrate Response Factor 1 (BRF1)
0.1 1.7 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.1 1.8 REACTOME RAP1 SIGNALLING Genes involved in Rap1 signalling
0.1 1.2 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.1 0.3 REACTOME BINDING AND ENTRY OF HIV VIRION Genes involved in Binding and entry of HIV virion
0.1 0.3 REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
0.1 0.1 REACTOME VIF MEDIATED DEGRADATION OF APOBEC3G Genes involved in Vif-mediated degradation of APOBEC3G
0.1 1.1 REACTOME REGULATION OF IFNG SIGNALING Genes involved in Regulation of IFNG signaling
0.1 2.4 REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE Genes involved in Synthesis of PIPs at the plasma membrane
0.1 1.6 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.1 0.4 REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.1 0.9 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.1 1.5 REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING Genes involved in Downregulation of TGF-beta receptor signaling
0.1 0.2 REACTOME RIP MEDIATED NFKB ACTIVATION VIA DAI Genes involved in RIP-mediated NFkB activation via DAI
0.1 0.6 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
0.1 1.1 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.1 0.2 REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION Genes involved in activated TAK1 mediates p38 MAPK activation
0.1 0.2 REACTOME PD1 SIGNALING Genes involved in PD-1 signaling
0.1 0.6 REACTOME SPRY REGULATION OF FGF SIGNALING Genes involved in Spry regulation of FGF signaling
0.1 1.3 REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.1 0.2 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.1 0.5 REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.1 1.5 REACTOME TRANSPORT OF RIBONUCLEOPROTEINS INTO THE HOST NUCLEUS Genes involved in Transport of Ribonucleoproteins into the Host Nucleus
0.1 1.5 REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.1 0.2 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.1 0.2 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
0.1 1.1 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.0 0.1 REACTOME IRAK1 RECRUITS IKK COMPLEX Genes involved in IRAK1 recruits IKK complex
0.0 0.4 REACTOME TRAF6 MEDIATED NFKB ACTIVATION Genes involved in TRAF6 mediated NF-kB activation
0.0 0.3 REACTOME RAF MAP KINASE CASCADE Genes involved in RAF/MAP kinase cascade
0.0 0.6 REACTOME IL RECEPTOR SHC SIGNALING Genes involved in Interleukin receptor SHC signaling
0.0 0.5 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.0 0.5 REACTOME PROLACTIN RECEPTOR SIGNALING Genes involved in Prolactin receptor signaling
0.0 0.4 REACTOME REGULATORY RNA PATHWAYS Genes involved in Regulatory RNA pathways
0.0 0.6 REACTOME COSTIMULATION BY THE CD28 FAMILY Genes involved in Costimulation by the CD28 family
0.0 0.2 REACTOME N GLYCAN ANTENNAE ELONGATION IN THE MEDIAL TRANS GOLGI Genes involved in N-glycan antennae elongation in the medial/trans-Golgi
0.0 1.4 REACTOME INTERFERON GAMMA SIGNALING Genes involved in Interferon gamma signaling
0.0 0.6 REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.0 1.7 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.0 0.8 REACTOME CHONDROITIN SULFATE BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
0.0 0.5 REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR Genes involved in Trafficking and processing of endosomal TLR
0.0 0.5 REACTOME CTNNB1 PHOSPHORYLATION CASCADE Genes involved in Beta-catenin phosphorylation cascade
0.0 0.2 REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY Genes involved in Regulation of the Fanconi anemia pathway
0.0 0.9 REACTOME INTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Intrinsic Pathway for Apoptosis
0.0 2.1 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0 0.2 REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.0 0.2 REACTOME DCC MEDIATED ATTRACTIVE SIGNALING Genes involved in DCC mediated attractive signaling
0.0 0.5 REACTOME P2Y RECEPTORS Genes involved in P2Y receptors
0.0 0.3 REACTOME ENDOSOMAL VACUOLAR PATHWAY Genes involved in Endosomal/Vacuolar pathway
0.0 0.9 REACTOME G0 AND EARLY G1 Genes involved in G0 and Early G1
0.0 0.6 REACTOME THE ROLE OF NEF IN HIV1 REPLICATION AND DISEASE PATHOGENESIS Genes involved in The role of Nef in HIV-1 replication and disease pathogenesis
0.0 0.6 REACTOME NOD1 2 SIGNALING PATHWAY Genes involved in NOD1/2 Signaling Pathway
0.0 1.4 REACTOME GLYCOSPHINGOLIPID METABOLISM Genes involved in Glycosphingolipid metabolism
0.0 0.1 REACTOME INTEGRATION OF PROVIRUS Genes involved in Integration of provirus
0.0 0.3 REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.0 0.1 REACTOME TGF BETA RECEPTOR SIGNALING ACTIVATES SMADS Genes involved in TGF-beta receptor signaling activates SMADs
0.0 0.1 REACTOME TRAF3 DEPENDENT IRF ACTIVATION PATHWAY Genes involved in TRAF3-dependent IRF activation pathway
0.0 0.3 REACTOME ASSOCIATION OF LICENSING FACTORS WITH THE PRE REPLICATIVE COMPLEX Genes involved in Association of licensing factors with the pre-replicative complex
0.0 0.5 REACTOME DOWNSTREAM TCR SIGNALING Genes involved in Downstream TCR signaling
0.0 0.0 REACTOME PKA MEDIATED PHOSPHORYLATION OF CREB Genes involved in PKA-mediated phosphorylation of CREB
0.0 1.0 REACTOME MRNA 3 END PROCESSING Genes involved in mRNA 3'-end processing
0.0 0.2 REACTOME PRE NOTCH PROCESSING IN GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.0 0.3 REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.0 0.3 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.0 0.1 REACTOME MTORC1 MEDIATED SIGNALLING Genes involved in mTORC1-mediated signalling
0.0 0.3 REACTOME SIGNALING BY FGFR1 FUSION MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.0 2.1 REACTOME MRNA SPLICING Genes involved in mRNA Splicing
0.0 0.1 REACTOME REGULATION OF SIGNALING BY CBL Genes involved in Regulation of signaling by CBL
0.0 0.6 REACTOME RECYCLING PATHWAY OF L1 Genes involved in Recycling pathway of L1
0.0 0.5 REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.0 0.5 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.0 0.7 REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS Genes involved in Apoptotic cleavage of cellular proteins
0.0 0.3 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
0.0 0.2 REACTOME COPI MEDIATED TRANSPORT Genes involved in COPI Mediated Transport
0.0 0.3 REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY Genes involved in Adenylate cyclase activating pathway
0.0 0.3 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.0 0.3 REACTOME METABOLISM OF NON CODING RNA Genes involved in Metabolism of non-coding RNA
0.0 0.3 REACTOME HIGHLY CALCIUM PERMEABLE POSTSYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Highly calcium permeable postsynaptic nicotinic acetylcholine receptors
0.0 0.4 REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.0 0.5 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.0 0.3 REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING Genes involved in Formation of ATP by chemiosmotic coupling
0.0 0.1 REACTOME NUCLEOTIDE LIKE PURINERGIC RECEPTORS Genes involved in Nucleotide-like (purinergic) receptors
0.0 0.3 REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.0 0.0 REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS Genes involved in Membrane binding and targetting of GAG proteins
0.0 0.1 REACTOME REGULATION OF INSULIN SECRETION BY GLUCAGON LIKE PEPTIDE1 Genes involved in Regulation of Insulin Secretion by Glucagon-like Peptide-1
0.0 0.1 REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.0 0.1 REACTOME DAG AND IP3 SIGNALING Genes involved in DAG and IP3 signaling
0.0 0.8 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.0 0.3 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.0 1.0 REACTOME ACTIVATION OF NF KAPPAB IN B CELLS Genes involved in Activation of NF-kappaB in B Cells
0.0 0.1 REACTOME INTERACTIONS OF VPR WITH HOST CELLULAR PROTEINS Genes involved in Interactions of Vpr with host cellular proteins
0.0 0.1 REACTOME INFLUENZA VIRAL RNA TRANSCRIPTION AND REPLICATION Genes involved in Influenza Viral RNA Transcription and Replication
0.0 0.1 REACTOME INHIBITION OF REPLICATION INITIATION OF DAMAGED DNA BY RB1 E2F1 Genes involved in Inhibition of replication initiation of damaged DNA by RB1/E2F1
0.0 0.1 REACTOME ACYL CHAIN REMODELLING OF PI Genes involved in Acyl chain remodelling of PI
0.0 0.3 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.0 0.2 REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.0 0.0 REACTOME PROSTACYCLIN SIGNALLING THROUGH PROSTACYCLIN RECEPTOR Genes involved in Prostacyclin signalling through prostacyclin receptor
0.0 1.2 REACTOME RESPIRATORY ELECTRON TRANSPORT ATP SYNTHESIS BY CHEMIOSMOTIC COUPLING AND HEAT PRODUCTION BY UNCOUPLING PROTEINS Genes involved in Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins.
0.0 0.3 REACTOME CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
0.0 0.4 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.0 1.2 REACTOME MITOTIC PROMETAPHASE Genes involved in Mitotic Prometaphase
0.0 0.2 REACTOME GLUCOSE TRANSPORT Genes involved in Glucose transport
0.0 0.1 REACTOME CREB PHOSPHORYLATION THROUGH THE ACTIVATION OF RAS Genes involved in CREB phosphorylation through the activation of Ras
0.0 0.3 REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.0 0.0 REACTOME P53 INDEPENDENT G1 S DNA DAMAGE CHECKPOINT Genes involved in p53-Independent G1/S DNA damage checkpoint
0.0 0.4 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.0 0.1 REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the early endosome membrane
0.0 0.0 REACTOME RETROGRADE NEUROTROPHIN SIGNALLING Genes involved in Retrograde neurotrophin signalling
0.0 0.2 REACTOME TRANSPORT TO THE GOLGI AND SUBSEQUENT MODIFICATION Genes involved in Transport to the Golgi and subsequent modification
0.0 0.2 REACTOME TRANSPORT OF ORGANIC ANIONS Genes involved in Transport of organic anions
0.0 0.2 REACTOME GLUCAGON TYPE LIGAND RECEPTORS Genes involved in Glucagon-type ligand receptors
0.0 1.6 REACTOME NONSENSE MEDIATED DECAY ENHANCED BY THE EXON JUNCTION COMPLEX Genes involved in Nonsense Mediated Decay Enhanced by the Exon Junction Complex
0.0 0.4 REACTOME SULFUR AMINO ACID METABOLISM Genes involved in Sulfur amino acid metabolism
0.0 0.1 REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.0 0.4 REACTOME GLUCONEOGENESIS Genes involved in Gluconeogenesis
0.0 0.1 REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES Genes involved in Recruitment of NuMA to mitotic centrosomes
0.0 0.7 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.0 0.0 REACTOME ABORTIVE ELONGATION OF HIV1 TRANSCRIPT IN THE ABSENCE OF TAT Genes involved in Abortive elongation of HIV-1 transcript in the absence of Tat
0.0 0.0 REACTOME P75NTR RECRUITS SIGNALLING COMPLEXES Genes involved in p75NTR recruits signalling complexes
0.0 0.2 REACTOME XENOBIOTICS Genes involved in Xenobiotics
0.0 0.1 REACTOME A TETRASACCHARIDE LINKER SEQUENCE IS REQUIRED FOR GAG SYNTHESIS Genes involved in A tetrasaccharide linker sequence is required for GAG synthesis
0.0 0.4 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.0 0.3 REACTOME SRP DEPENDENT COTRANSLATIONAL PROTEIN TARGETING TO MEMBRANE Genes involved in SRP-dependent cotranslational protein targeting to membrane
0.0 0.1 REACTOME RNA POL I TRANSCRIPTION INITIATION Genes involved in RNA Polymerase I Transcription Initiation
0.0 0.0 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.0 1.5 REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.0 0.0 REACTOME POST NMDA RECEPTOR ACTIVATION EVENTS Genes involved in Post NMDA receptor activation events
0.0 0.1 REACTOME BASIGIN INTERACTIONS Genes involved in Basigin interactions
0.0 0.1 REACTOME FORMATION OF INCISION COMPLEX IN GG NER Genes involved in Formation of incision complex in GG-NER
0.0 0.0 REACTOME SCFSKP2 MEDIATED DEGRADATION OF P27 P21 Genes involved in SCF(Skp2)-mediated degradation of p27/p21
0.0 0.3 REACTOME REGULATION OF WATER BALANCE BY RENAL AQUAPORINS Genes involved in Regulation of Water Balance by Renal Aquaporins
0.0 0.2 REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.0 0.1 REACTOME ENOS ACTIVATION AND REGULATION Genes involved in eNOS activation and regulation
0.0 0.1 REACTOME GRB2 SOS PROVIDES LINKAGE TO MAPK SIGNALING FOR INTERGRINS Genes involved in GRB2:SOS provides linkage to MAPK signaling for Intergrins
0.0 0.1 REACTOME FORMATION OF TRANSCRIPTION COUPLED NER TC NER REPAIR COMPLEX Genes involved in Formation of transcription-coupled NER (TC-NER) repair complex
0.0 0.1 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.0 0.0 REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.0 0.7 REACTOME G ALPHA S SIGNALLING EVENTS Genes involved in G alpha (s) signalling events
0.0 0.1 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor
0.0 0.2 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.0 0.1 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.0 0.4 REACTOME BETA DEFENSINS Genes involved in Beta defensins
0.0 0.1 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.0 0.6 REACTOME MEIOTIC SYNAPSIS Genes involved in Meiotic Synapsis
0.0 0.1 REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.0 0.1 REACTOME ELONGATION ARREST AND RECOVERY Genes involved in Elongation arrest and recovery