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ENCODE: H3K4me1 ChIP-Seq of primary human cells

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Results for NKX6-2

Z-value: 2.14

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Transcription factors associated with NKX6-2

Gene Symbol	Gene ID	Gene Info
NKX6-2 Ensembl NCBI GeneCards UniProt	ENSG00000148826.6	NK6 homeobox 2

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE	Gene	Distance	Association probability	Pearson corr. coef.	P-value	Plot
chr10_134598432_134598644	NKX6-2	1018	0.580244	0.64	6.4e-02	Click!
chr10_134600865_134601148	NKX6-2	1450	0.451325	0.56	1.1e-01	Click!
chr10_134601421_134601572	NKX6-2	1940	0.366190	0.36	3.3e-01	Click!
chr10_134601644_134601795	NKX6-2	2163	0.340700	0.29	4.5e-01	Click!
chr10_134601938_134602089	NKX6-2	2457	0.315131	0.22	5.7e-01	Click!

Activity of the NKX6-2 motif across conditions

Conditions sorted by the z-value of the NKX6-2 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE)	Target Score	Top associated gene	Gene Info	Distance of CRE to TSS	CRE/Gene association probability
chr8_124099579_124099969	1.33	TBC1D31	TBC1 domain family, member 31	6127	0.18
chr17_37970513_37970744	0.98	IKZF3	IKAROS family zinc finger 3 (Aiolos)	36150	0.11
chr14_91534430_91534736	0.92	C14orf159	chromosome 14 open reading frame 159	7407	0.17
chr6_154561193_154561344	0.92	IPCEF1	interaction protein for cytohesin exchange factors 1	6722	0.33
chr13_114910310_114910591	0.88	RASA3	RAS p21 protein activator 3	12364	0.21
chr9_78641347_78641498	0.85	PCSK5	proprotein convertase subtilisin/kexin type 5	69471	0.13
chr1_65342372_65342702	0.80	JAK1	Janus kinase 1	89650	0.08
chr11_104578420_104578571	0.78	CASP12	caspase 12 (gene/pseudogene)	190646	0.03
chr7_70135162_70135313	0.75	AUTS2	autism susceptibility candidate 2	58888	0.17
chr5_55996080_55996447	0.74	AC022431.2	Homo sapiens uncharacterized LOC101928448 (LOC101928448), mRNA.	94204	0.07
chrX_135709367_135709640	0.73	ENSG00000233093	.	12199	0.16
chr12_112431054_112431322	0.73	TMEM116	transmembrane protein 116	12601	0.16
chr7_27675628_27675779	0.73	HIBADH	3-hydroxyisobutyrate dehydrogenase	11672	0.27
chr17_67413122_67413352	0.72	MAP2K6	mitogen-activated protein kinase kinase 6	2398	0.38
chr2_62435329_62435921	0.71	ENSG00000266097	.	2664	0.25
chr4_48139194_48139484	0.68	TXK	TXK tyrosine kinase	3066	0.22
chr6_11276274_11276599	0.68	NEDD9	neural precursor cell expressed, developmentally down-regulated 9	43521	0.17
chr21_34722859_34723079	0.68	IFNAR1	interferon (alpha, beta and omega) receptor 1	25691	0.15
chr6_52151332_52151486	0.68	MCM3	minichromosome maintenance complex component 3	1774	0.39
chr13_114914753_114915138	0.68	RASA3	RAS p21 protein activator 3	16859	0.2
chr16_81748374_81748687	0.68	PLCG2	phospholipase C, gamma 2 (phosphatidylinositol-specific)	24172	0.24
chr12_837359_837675	0.68	WNK1	WNK lysine deficient protein kinase 1	24242	0.18
chr1_76733623_76733774	0.68	ST6GALNAC3	ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 3	193294	0.03
chr7_142509740_142509902	0.67	PRSS3P2	protease, serine, 3 pseudogene 2	28690	0.14
chr14_22997541_22997805	0.64	TRAJ15	T cell receptor alpha joining 15	907	0.43
chr5_80304301_80304452	0.64	CTC-459I6.1		47650	0.15
chr6_160112586_160112797	0.64	SOD2	superoxide dismutase 2, mitochondrial	1569	0.36
chr12_96591690_96592082	0.64	ELK3	ELK3, ETS-domain protein (SRF accessory protein 2)	3494	0.26
chr5_72148296_72148452	0.63	TNPO1	transportin 1	4363	0.23
chr13_114912317_114912766	0.63	RASA3	RAS p21 protein activator 3	14455	0.21
chr22_42614958_42615109	0.63	TCF20	transcription factor 20 (AR1)	3585	0.24
chr22_19877368_19877581	0.62	GNB1L	guanine nucleotide binding protein (G protein), beta polypeptide 1-like	35012	0.1
chr3_18478462_18478755	0.62	SATB1	SATB homeobox 1	1576	0.42
chr3_45047049_45047200	0.62	CLEC3B	C-type lectin domain family 3, member B	20551	0.14
chr2_182062690_182062873	0.61	ENSG00000266705	.	107598	0.07
chr21_35305571_35305790	0.61	LINC00649	long intergenic non-protein coding RNA 649	2162	0.26
chr10_22923403_22923554	0.61	PIP4K2A	phosphatidylinositol-5-phosphate 4-kinase, type II, alpha	42836	0.2
chr22_40798855_40799170	0.61	SGSM3	small G protein signaling modulator 3	5305	0.17
chr1_22431010_22431376	0.60	WNT4	wingless-type MMTV integration site family, member 4	25151	0.14
chr15_44890096_44890365	0.60	SPG11	spastic paraplegia 11 (autosomal recessive)	12825	0.16
chr1_117346836_117346988	0.60	CD2	CD2 molecule	49823	0.13
chr13_74599951_74600133	0.60	KLF12	Kruppel-like factor 12	30856	0.26
chr16_80690009_80690168	0.59	ENSG00000265341	.	9372	0.18
chr2_48116432_48116617	0.59	FBXO11	F-box protein 11	666	0.75
chr12_59972826_59972977	0.59	ENSG00000202471	.	7823	0.19
chr12_123721163_123721324	0.59	C12orf65	chromosome 12 open reading frame 65	2941	0.17
chr18_29639731_29640017	0.59	ENSG00000265063	.	1078	0.43
chr2_48116625_48116776	0.59	FBXO11	F-box protein 11	842	0.67
chr10_92962405_92962639	0.59	PCGF5	polycomb group ring finger 5	17386	0.29
chr6_44898953_44899135	0.58	SUPT3H	suppressor of Ty 3 homolog (S. cerevisiae)	24203	0.27
chr6_119226723_119226983	0.58	ASF1A	anti-silencing function 1A histone chaperone	11469	0.19
chr16_79320751_79320982	0.58	ENSG00000222244	.	22515	0.27
chrX_78211984_78212141	0.57	P2RY10	purinergic receptor P2Y, G-protein coupled, 10	11144	0.31
chr15_44040682_44040851	0.57	PDIA3	protein disulfide isomerase family A, member 3	2115	0.14
chr2_74401777_74401928	0.57	MOB1A	MOB kinase activator 1A	1908	0.23
chr8_133626087_133626238	0.57	LRRC6	leucine rich repeat containing 6	8772	0.26
chr2_68379059_68379228	0.57	WDR92	WD repeat domain 92	5462	0.18
chr4_103551516_103551667	0.57	NFKB1	nuclear factor of kappa light polypeptide gene enhancer in B-cells 1	52570	0.14
chr1_121292871_121293072	0.57	FCGR1B	Fc fragment of IgG, high affinity Ib, receptor (CD64)	357034	0.01
chr13_48723598_48723758	0.57	MED4	mediator complex subunit 4	54411	0.13
chrX_118813796_118814051	0.57	SEPT6	septin 6	12869	0.17
chr5_175435816_175435967	0.56	THOC3	THO complex 3	25792	0.12
chr4_109071133_109071543	0.56	LEF1	lymphoid enhancer-binding factor 1	16119	0.22
chr12_40015334_40015536	0.56	ABCD2	ATP-binding cassette, sub-family D (ALD), member 2	1882	0.39
chr1_90164458_90164609	0.56	LRRC8C	leucine rich repeat containing 8 family, member C	65902	0.09
chr14_99726600_99726784	0.56	AL109767.1		2593	0.31
chr15_70848608_70848759	0.55	UACA	uveal autoantigen with coiled-coil domains and ankyrin repeats	145937	0.05
chr13_75891307_75891494	0.55	TBC1D4	TBC1 domain family, member 4	24267	0.22
chr4_109081453_109081912	0.55	LEF1	lymphoid enhancer-binding factor 1	5775	0.24
chr12_49311245_49311396	0.55	FKBP11	FK506 binding protein 11, 19 kDa	7430	0.08
chr3_192616183_192616516	0.54	MB21D2	Mab-21 domain containing 2	19601	0.27
chr15_34901578_34901729	0.54	ENSG00000252425	.	11894	0.17
chr17_63021688_63021862	0.54	RP11-583F2.5		26252	0.14
chr5_169700107_169700517	0.54	LCP2	lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa)	5981	0.24
chr1_92832899_92833115	0.53	ENSG00000242764	.	35235	0.17
chr14_61968102_61968253	0.53	RP11-47I22.4		27669	0.17
chr17_46506357_46506540	0.53	SKAP1	src kinase associated phosphoprotein 1	1104	0.43
chr10_7554785_7554936	0.53	RP11-385N23.1		20309	0.21
chr1_76751688_76751938	0.53	ST6GALNAC3	ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 3	211409	0.02
chr7_143519219_143519499	0.53	RP11-61L23.2		11603	0.19
chr4_78777778_78777929	0.53	MRPL1	mitochondrial ribosomal protein L1	5821	0.28
chr6_149829598_149829769	0.53	ENSG00000252244	.	8409	0.14
chr5_37110577_37110728	0.52	NIPBL	Nipped-B homolog (Drosophila)	51647	0.15
chr16_87732221_87732372	0.52	AC010536.1	Uncharacterized protein; cDNA FLJ45526 fis, clone BRTHA2027227	2543	0.25
chr16_79311831_79311982	0.52	ENSG00000222244	.	13555	0.29
chr1_173498223_173498374	0.52	RP3-436N22.3		26092	0.16
chr11_116824518_116824694	0.52	SIK3	SIK family kinase 3	3154	0.24
chr3_4890845_4890996	0.52	ENSG00000239126	.	29466	0.18
chr4_71602631_71602782	0.51	RUFY3	RUN and FYVE domain containing 3	2555	0.21
chr6_158779170_158779472	0.51	RP11-732M18.2		40272	0.15
chr4_39030463_39030661	0.51	TMEM156	transmembrane protein 156	3479	0.26
chr16_3624376_3624684	0.51	NLRC3	NLR family, CARD domain containing 3	2862	0.2
chr20_5573418_5573569	0.51	GPCPD1	glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae)	17339	0.24
chr5_112223439_112223590	0.51	ZRSR1	zinc finger (CCCH type), RNA-binding motif and serine/arginine rich 1	3799	0.15
chr17_28066618_28066769	0.51	RP11-82O19.1		21428	0.14
chr12_838464_838718	0.50	WNK1	WNK lysine deficient protein kinase 1	23168	0.18
chr6_16486034_16486185	0.50	ENSG00000265642	.	57355	0.16
chr1_110047130_110047281	0.50	AMIGO1	adhesion molecule with Ig-like domain 1	5099	0.11
chr5_154209177_154209349	0.50	ENSG00000263361	.	245	0.91
chr7_143411572_143411945	0.50	FAM115C	family with sequence similarity 115, member C	110	0.97
chr12_113523386_113523537	0.49	DTX1	deltex homolog 1 (Drosophila)	27966	0.13
chr14_64963769_64963936	0.49	ZBTB1	zinc finger and BTB domain containing 1	6591	0.12
chr13_28015570_28015856	0.49	MTIF3	mitochondrial translational initiation factor 3	8613	0.17
chr20_31121588_31121799	0.49	C20orf112	chromosome 20 open reading frame 112	2507	0.26
chr3_27522075_27522308	0.49	SLC4A7	solute carrier family 4, sodium bicarbonate cotransporter, member 7	3647	0.25
chr7_143332335_143332716	0.49	FAM115C	family with sequence similarity 115, member C	13980	0.19
chr17_33844037_33844188	0.49	RP11-1094M14.5		6823	0.12
chr3_114052420_114052571	0.49	ENSG00000207770	.	17079	0.16
chr12_90094188_90094339	0.49	ATP2B1	ATPase, Ca++ transporting, plasma membrane 1	8345	0.21
chr17_14054887_14055038	0.49	ENSG00000252305	.	25486	0.19
chr12_102093794_102093945	0.49	CHPT1	choline phosphotransferase 1	2419	0.21
chr8_82100250_82100582	0.49	PAG1	phosphoprotein associated with glycosphingolipid microdomains 1	76113	0.1
chr9_132656304_132656600	0.49	FNBP1	formin binding protein 1	25137	0.14
chr1_197917676_197917990	0.49	LHX9	LIM homeobox 9	31304	0.2
chr14_61752769_61752920	0.49	TMEM30B	transmembrane protein 30B	4286	0.2
chr4_153168335_153168486	0.49	ENSG00000244544	.	17187	0.21
chr3_136638868_136639019	0.49	NCK1	NCK adaptor protein 1	7938	0.2
chr14_50571344_50571545	0.48	VCPKMT	valosin containing protein lysine (K) methyltransferase	11831	0.15
chr15_60828599_60828948	0.48	CTD-2501E16.2		6601	0.21
chr10_131968105_131968342	0.48	GLRX3	glutaredoxin 3	33560	0.24
chr3_71537410_71537957	0.48	ENSG00000221264	.	53557	0.14
chr2_228329125_228329444	0.48	ENSG00000266382	.	7564	0.21
chr1_193448919_193449104	0.48	ENSG00000252241	.	252063	0.02
chr11_102175134_102175285	0.48	ENSG00000212466	.	9244	0.18
chr10_11189349_11189500	0.48	CELF2	CUGBP, Elav-like family member 2	17569	0.19
chr19_19469259_19469410	0.48	MAU2	MAU2 sister chromatid cohesion factor	21319	0.12
chr3_4892401_4892676	0.48	ENSG00000239126	.	27848	0.18
chrX_48784339_48784490	0.48	PIM2	pim-2 oncogene	8113	0.1
chr12_40009917_40010068	0.48	ABCD2	ATP-binding cassette, sub-family D (ALD), member 2	3561	0.29
chr5_55267605_55267756	0.48	IL6ST	interleukin 6 signal transducer (gp130, oncostatin M receptor)	4426	0.18
chr4_40303302_40303674	0.47	CHRNA9	cholinergic receptor, nicotinic, alpha 9 (neuronal)	33858	0.17
chr12_93827062_93827301	0.47	UBE2N	ubiquitin-conjugating enzyme E2N	7851	0.16
chr5_133881433_133881702	0.47	JADE2	jade family PHD finger 2	19240	0.15
chr15_86248083_86248451	0.47	RP11-815J21.1		3927	0.14
chr2_36473322_36473473	0.47	CRIM1	cysteine rich transmembrane BMP regulator 1 (chordin-like)	109672	0.07
chr3_16416476_16416627	0.47	RP11-415F23.4		29918	0.16
chr8_128203988_128204139	0.47	POU5F1B	POU class 5 homeobox 1B	222472	0.02
chr2_191993579_191993809	0.47	ENSG00000207402	.	7018	0.22
chr2_97258809_97258960	0.47	KANSL3	KAT8 regulatory NSL complex subunit 3	45162	0.12
chr7_1086396_1086547	0.47	GPR146	G protein-coupled receptor 146	2259	0.16
chr21_32530819_32530970	0.47	TIAM1	T-cell lymphoma invasion and metastasis 1	28355	0.24
chr9_31323752_31324057	0.47	ENSG00000211510	.	549678	0.0
chr17_30844651_30844802	0.47	RP11-466A19.3		1245	0.28
chr5_138965662_138965904	0.47	UBE2D2	ubiquitin-conjugating enzyme E2D 2	24169	0.15
chr2_120685287_120685686	0.46	PTPN4	protein tyrosine phosphatase, non-receptor type 4 (megakaryocyte)	1866	0.39
chr7_107499957_107500108	0.46	DLD	dihydrolipoamide dehydrogenase	31383	0.16
chr13_113624966_113625117	0.46	MCF2L	MCF.2 cell line derived transforming sequence-like	1506	0.31
chr6_135424557_135424726	0.46	HBS1L	HBS1-like (S. cerevisiae)	447	0.86
chr10_115721889_115722163	0.46	AL162407.1	CDNA FLJ20147 fis, clone COL07954; HCG1781466; Uncharacterized protein	47496	0.14
chr5_61639146_61639342	0.46	KIF2A	kinesin heavy chain member 2A	17889	0.22
chr1_111214021_111214215	0.46	KCNA3	potassium voltage-gated channel, shaker-related subfamily, member 3	3537	0.23
chr1_42496804_42497120	0.46	HIVEP3	human immunodeficiency virus type I enhancer binding protein 3	112584	0.06
chr2_191936002_191936213	0.46	ENSG00000231858	.	49855	0.11
chr1_172349072_172349255	0.46	DNM3	dynamin 3	1005	0.51
chr9_98778423_98778577	0.46	ERCC6L2	excision repair cross-complementing rodent repair deficiency, complementation group 6-like 2	43381	0.17
chr14_92264132_92264283	0.46	TC2N	tandem C2 domains, nuclear	1135	0.5
chr11_121452316_121452687	0.46	SORL1	sortilin-related receptor, L(DLR class) A repeats containing	4954	0.34
chr8_42187611_42187890	0.46	POLB	polymerase (DNA directed), beta	8222	0.18
chr5_55397703_55397854	0.46	ANKRD55	ankyrin repeat domain 55	15000	0.17
chr14_99662260_99662411	0.46	AL162151.4		37582	0.18
chr12_112440617_112440858	0.46	TMEM116	transmembrane protein 116	3052	0.22
chr1_101645257_101645426	0.45	ENSG00000252765	.	46632	0.11
chr3_140980291_140980442	0.45	ACPL2	acid phosphatase-like 2	482	0.86
chr17_39494241_39494487	0.45	KRT33A	keratin 33A	12700	0.08
chr14_59972219_59972370	0.45	JKAMP	JNK1/MAPK8-associated membrane protein	20505	0.17
chr3_113939513_113939664	0.45	RP11-553L6.2		6350	0.18
chr6_143173561_143173779	0.45	HIVEP2	human immunodeficiency virus type I enhancer binding protein 2	15486	0.27
chr1_224032893_224033044	0.45	TP53BP2	tumor protein p53 binding protein, 2	664	0.79
chr17_55614689_55614904	0.45	RP11-118E18.2		13838	0.23
chr2_237276096_237276313	0.45	RP11-785G17.1		1	0.98
chr8_134081545_134081796	0.45	SLA	Src-like-adaptor	9067	0.25
chr9_100865715_100865872	0.45	TRIM14	tripartite motif containing 14	10950	0.19
chr14_23013063_23013415	0.44	AE000662.92	Uncharacterized protein	12295	0.1
chr19_23598893_23599044	0.44	ZNF91	zinc finger protein 91	20606	0.25
chr1_110043711_110043925	0.44	CYB561D1	cytochrome b561 family, member D1	7081	0.11
chr8_19245453_19245604	0.44	SH2D4A	SH2 domain containing 4A	68427	0.14
chr14_98654810_98655207	0.44	ENSG00000222066	.	143079	0.05
chr2_235281672_235281823	0.44	ARL4C	ADP-ribosylation factor-like 4C	123497	0.06
chr17_37946623_37946846	0.44	IKZF3	IKAROS family zinc finger 3 (Aiolos)	12256	0.14
chr20_35646828_35646979	0.44	RBL1	retinoblastoma-like 1 (p107)	49555	0.13
chr6_149801184_149801367	0.44	ZC3H12D	zinc finger CCCH-type containing 12D	2994	0.22
chr8_121736860_121737223	0.44	RP11-713M15.1		36452	0.2
chr3_31257407_31257558	0.44	ENSG00000222983	.	12725	0.27
chr5_35761673_35761824	0.44	SPEF2	sperm flagellar 2	17522	0.22
chr17_37116490_37116784	0.44	FBXO47	F-box protein 47	7018	0.14
chr2_197125827_197126091	0.44	AC020571.3		802	0.65
chrX_128871427_128871642	0.44	XPNPEP2	X-prolyl aminopeptidase (aminopeptidase P) 2, membrane-bound	1416	0.46
chr3_151901754_151901973	0.44	MBNL1	muscleblind-like splicing regulator 1	83966	0.09
chr4_40205358_40205579	0.44	RHOH	ras homolog family member H	3504	0.27
chr6_138121093_138121244	0.43	ENSG00000207300	.	15657	0.2
chr14_90107458_90107875	0.43	ENSG00000252655	.	9581	0.14
chr2_238621913_238622064	0.43	LRRFIP1	leucine rich repeat (in FLII) interacting protein 1	21006	0.21
chrX_13023409_13023615	0.43	TMSB4X	thymosin beta 4, X-linked	29735	0.18
chr4_38684598_38684828	0.43	RP11-617D20.1		18209	0.16
chr14_99702124_99702472	0.43	AL109767.1		26987	0.19
chr15_52780606_52780799	0.43	MYO5A	myosin VA (heavy chain 12, myoxin)	40336	0.16
chr18_60828109_60828350	0.43	RP11-299P2.1		9676	0.23
chr7_110617923_110618107	0.43	ENSG00000221279	.	49641	0.18
chr16_53483526_53483774	0.43	RBL2	retinoblastoma-like 2 (p130)	338	0.77
chr2_181992682_181992833	0.43	UBE2E3	ubiquitin-conjugating enzyme E2E 3	146007	0.04

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of NKX6-2

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	1.3	GO:0035246	peptidyl-arginine N-methylation(GO:0035246)
0.2	0.5	GO:0010040	response to iron(II) ion(GO:0010040)
0.1	0.6	GO:0033152	immunoglobulin V(D)J recombination(GO:0033152)
0.1	0.3	GO:0060394	negative regulation of pathway-restricted SMAD protein phosphorylation(GO:0060394)
0.1	0.6	GO:0030854	positive regulation of granulocyte differentiation(GO:0030854)
0.1	0.4	GO:0010956	negative regulation of calcidiol 1-monooxygenase activity(GO:0010956) negative regulation of vitamin D biosynthetic process(GO:0010957) negative regulation of vitamin metabolic process(GO:0046137)
0.1	0.4	GO:0031580	membrane raft polarization(GO:0001766) membrane raft distribution(GO:0031580)
0.1	0.4	GO:0007352	zygotic specification of dorsal/ventral axis(GO:0007352)
0.1	0.6	GO:0045898	regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045898)
0.1	0.2	GO:0097300	necroptotic process(GO:0070266) programmed necrotic cell death(GO:0097300)
0.1	0.3	GO:0001672	regulation of chromatin assembly or disassembly(GO:0001672)
0.1	0.2	GO:0050862	positive regulation of T cell receptor signaling pathway(GO:0050862)
0.1	0.4	GO:0046642	negative regulation of alpha-beta T cell proliferation(GO:0046642)
0.1	0.4	GO:0001911	negative regulation of leukocyte mediated cytotoxicity(GO:0001911)
0.1	0.3	GO:0051533	positive regulation of NFAT protein import into nucleus(GO:0051533)
0.1	0.1	GO:0002513	tolerance induction to self antigen(GO:0002513)
0.1	0.3	GO:0019276	UDP-N-acetylgalactosamine metabolic process(GO:0019276)
0.1	0.3	GO:0007571	age-dependent response to oxidative stress(GO:0001306) age-dependent general metabolic decline(GO:0007571)
0.1	0.1	GO:0060523	prostate epithelial cord elongation(GO:0060523)
0.1	0.4	GO:0006104	succinyl-CoA metabolic process(GO:0006104)
0.1	0.3	GO:0060916	mesenchymal cell proliferation involved in lung development(GO:0060916)
0.1	0.3	GO:0035066	positive regulation of histone acetylation(GO:0035066) positive regulation of protein acetylation(GO:1901985) positive regulation of peptidyl-lysine acetylation(GO:2000758)
0.1	0.3	GO:0042511	positive regulation of tyrosine phosphorylation of Stat1 protein(GO:0042511)
0.1	0.3	GO:0010761	fibroblast migration(GO:0010761)
0.1	0.5	GO:0045066	regulatory T cell differentiation(GO:0045066)
0.1	0.5	GO:0002335	mature B cell differentiation(GO:0002335)
0.1	0.2	GO:0060743	epithelial cell maturation involved in prostate gland development(GO:0060743)
0.1	0.6	GO:0006491	N-glycan processing(GO:0006491)
0.1	0.4	GO:0050667	homocysteine metabolic process(GO:0050667)
0.1	0.3	GO:0043951	negative regulation of cAMP-mediated signaling(GO:0043951)
0.1	0.1	GO:0060789	hair follicle placode formation(GO:0060789)
0.1	0.4	GO:0032527	protein exit from endoplasmic reticulum(GO:0032527)
0.1	0.2	GO:0031946	regulation of glucocorticoid biosynthetic process(GO:0031946)
0.1	0.2	GO:0006167	AMP biosynthetic process(GO:0006167)
0.1	0.2	GO:0009296	obsolete flagellum assembly(GO:0009296)
0.1	0.2	GO:0034085	establishment of sister chromatid cohesion(GO:0034085) cohesin loading(GO:0071921) regulation of cohesin loading(GO:0071922)
0.1	0.3	GO:0032486	Rap protein signal transduction(GO:0032486)
0.1	0.1	GO:0002326	B cell lineage commitment(GO:0002326)
0.1	0.3	GO:0007256	activation of JNKK activity(GO:0007256)
0.1	0.5	GO:0051491	positive regulation of filopodium assembly(GO:0051491)
0.1	0.1	GO:0045059	positive thymic T cell selection(GO:0045059)
0.1	0.3	GO:0002726	positive regulation of T cell cytokine production(GO:0002726)
0.1	0.3	GO:0032876	regulation of DNA endoreduplication(GO:0032875) negative regulation of DNA endoreduplication(GO:0032876) DNA endoreduplication(GO:0042023)
0.1	0.6	GO:0043550	regulation of lipid kinase activity(GO:0043550)
0.1	0.2	GO:0035520	monoubiquitinated protein deubiquitination(GO:0035520)
0.1	0.2	GO:0045722	positive regulation of gluconeogenesis(GO:0045722)
0.1	0.5	GO:0007172	signal complex assembly(GO:0007172)
0.1	0.2	GO:0006290	pyrimidine dimer repair(GO:0006290)
0.1	0.1	GO:0071801	regulation of podosome assembly(GO:0071801) positive regulation of podosome assembly(GO:0071803)
0.1	0.1	GO:0010572	positive regulation of platelet activation(GO:0010572)
0.1	0.1	GO:0042091	interleukin-10 biosynthetic process(GO:0042091) regulation of interleukin-10 biosynthetic process(GO:0045074)
0.1	0.2	GO:0006556	S-adenosylmethionine biosynthetic process(GO:0006556)
0.1	0.1	GO:0051132	NK T cell activation(GO:0051132)
0.1	0.2	GO:0009048	dosage compensation by inactivation of X chromosome(GO:0009048)
0.1	0.2	GO:0001831	trophectodermal cellular morphogenesis(GO:0001831)
0.1	0.1	GO:0060242	contact inhibition(GO:0060242)
0.1	0.1	GO:1901419	regulation of response to alcohol(GO:1901419)
0.1	0.2	GO:0006089	lactate metabolic process(GO:0006089)
0.1	0.3	GO:0007023	post-chaperonin tubulin folding pathway(GO:0007023)
0.1	0.4	GO:0006105	succinate metabolic process(GO:0006105)
0.1	0.2	GO:0030186	melatonin metabolic process(GO:0030186) melatonin biosynthetic process(GO:0030187)
0.1	0.2	GO:0042726	flavin-containing compound metabolic process(GO:0042726)
0.1	0.1	GO:0042109	lymphotoxin A production(GO:0032641) lymphotoxin A biosynthetic process(GO:0042109)
0.1	0.2	GO:0090286	cytoskeletal anchoring at nuclear membrane(GO:0090286)
0.1	0.3	GO:0018027	peptidyl-lysine dimethylation(GO:0018027)
0.1	0.2	GO:0006591	ornithine metabolic process(GO:0006591)
0.1	0.2	GO:1901341	activation of store-operated calcium channel activity(GO:0032237) regulation of store-operated calcium channel activity(GO:1901339) positive regulation of store-operated calcium channel activity(GO:1901341)
0.1	0.3	GO:0042159	lipoprotein catabolic process(GO:0042159)
0.1	0.4	GO:0048013	ephrin receptor signaling pathway(GO:0048013)
0.1	0.3	GO:0000729	DNA double-strand break processing(GO:0000729)
0.1	0.2	GO:0031125	rRNA 3'-end processing(GO:0031125)
0.1	0.1	GO:0045541	negative regulation of cholesterol biosynthetic process(GO:0045541) negative regulation of cholesterol metabolic process(GO:0090206)
0.1	0.2	GO:0032968	positive regulation of transcription elongation from RNA polymerase II promoter(GO:0032968)
0.0	0.4	GO:0002834	regulation of response to tumor cell(GO:0002834) positive regulation of response to tumor cell(GO:0002836) regulation of immune response to tumor cell(GO:0002837) positive regulation of immune response to tumor cell(GO:0002839)
0.0	0.3	GO:0043383	negative T cell selection(GO:0043383)
0.0	0.1	GO:0034201	response to oleic acid(GO:0034201)
0.0	0.2	GO:0008291	acetylcholine metabolic process(GO:0008291) acetate ester metabolic process(GO:1900619)
0.0	0.2	GO:0032988	ribonucleoprotein complex disassembly(GO:0032988)
0.0	0.2	GO:0042989	sequestering of actin monomers(GO:0042989)
0.0	0.1	GO:0006573	valine metabolic process(GO:0006573)
0.0	0.1	GO:0018076	N-terminal peptidyl-lysine acetylation(GO:0018076)
0.0	0.0	GO:0033091	positive regulation of immature T cell proliferation(GO:0033091)
0.0	0.1	GO:0047484	regulation of response to osmotic stress(GO:0047484)
0.0	0.2	GO:0070934	CRD-mediated mRNA stabilization(GO:0070934)
0.0	0.2	GO:0031936	negative regulation of chromatin silencing(GO:0031936)
0.0	0.1	GO:0090322	regulation of superoxide metabolic process(GO:0090322)
0.0	0.2	GO:0015853	adenine transport(GO:0015853)
0.0	0.2	GO:0032933	SREBP signaling pathway(GO:0032933) cellular response to sterol depletion(GO:0071501)
0.0	0.2	GO:0019987	obsolete negative regulation of anti-apoptosis(GO:0019987)
0.0	0.0	GO:0033148	positive regulation of intracellular estrogen receptor signaling pathway(GO:0033148)
0.0	0.1	GO:0032823	regulation of natural killer cell differentiation(GO:0032823) positive regulation of natural killer cell differentiation(GO:0032825)
0.0	0.1	GO:0031223	auditory behavior(GO:0031223)
0.0	0.1	GO:0040016	embryonic cleavage(GO:0040016)
0.0	0.2	GO:0001553	luteinization(GO:0001553)
0.0	0.4	GO:0008608	attachment of spindle microtubules to kinetochore(GO:0008608)
0.0	0.0	GO:1902931	negative regulation of alcohol biosynthetic process(GO:1902931)
0.0	0.0	GO:0001787	natural killer cell proliferation(GO:0001787)
0.0	0.1	GO:0045163	clustering of voltage-gated potassium channels(GO:0045163)
0.0	0.4	GO:0019059	obsolete initiation of viral infection(GO:0019059)
0.0	0.3	GO:0060123	regulation of growth hormone secretion(GO:0060123)
0.0	0.3	GO:0045672	positive regulation of osteoclast differentiation(GO:0045672)
0.0	0.1	GO:0046831	regulation of RNA export from nucleus(GO:0046831)
0.0	0.1	GO:0050685	positive regulation of mRNA 3'-end processing(GO:0031442) positive regulation of mRNA processing(GO:0050685) positive regulation of mRNA metabolic process(GO:1903313)
0.0	0.1	GO:0051832	evasion or tolerance of host defenses by virus(GO:0019049) avoidance of host defenses(GO:0044413) evasion or tolerance of host defenses(GO:0044415) avoidance of defenses of other organism involved in symbiotic interaction(GO:0051832) evasion or tolerance of defenses of other organism involved in symbiotic interaction(GO:0051834)
0.0	0.1	GO:1901970	positive regulation of mitotic metaphase/anaphase transition(GO:0045842) positive regulation of mitotic sister chromatid separation(GO:1901970) positive regulation of metaphase/anaphase transition of cell cycle(GO:1902101)
0.0	0.1	GO:0043117	positive regulation of vascular permeability(GO:0043117)
0.0	0.1	GO:0045056	transcytosis(GO:0045056)
0.0	0.1	GO:0021798	forebrain dorsal/ventral pattern formation(GO:0021798)
0.0	0.1	GO:0034776	response to histamine(GO:0034776)
0.0	0.2	GO:0043518	negative regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043518) negative regulation of signal transduction by p53 class mediator(GO:1901797)
0.0	2.6	GO:0050852	T cell receptor signaling pathway(GO:0050852)
0.0	0.1	GO:0072600	protein targeting to Golgi(GO:0000042) establishment of protein localization to Golgi(GO:0072600)
0.0	0.2	GO:0045356	positive regulation of interferon-alpha biosynthetic process(GO:0045356)
0.0	0.2	GO:0048096	chromatin-mediated maintenance of transcription(GO:0048096)
0.0	0.1	GO:0032506	cytokinetic process(GO:0032506)
0.0	0.1	GO:0014874	response to stimulus involved in regulation of muscle adaptation(GO:0014874)
0.0	0.1	GO:0022614	membrane to membrane docking(GO:0022614)
0.0	0.3	GO:0000381	regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.0	0.2	GO:0003310	pancreatic A cell differentiation(GO:0003310)
0.0	0.1	GO:0046532	regulation of photoreceptor cell differentiation(GO:0046532)
0.0	0.1	GO:1904358	positive regulation of telomere maintenance via telomerase(GO:0032212) positive regulation of telomere maintenance via telomere lengthening(GO:1904358)
0.0	0.1	GO:0070265	necrotic cell death(GO:0070265)
0.0	0.1	GO:0034629	cellular protein complex localization(GO:0034629)
0.0	0.1	GO:0033522	histone H2A ubiquitination(GO:0033522)
0.0	0.0	GO:0061154	endothelial tube morphogenesis(GO:0061154)
0.0	0.5	GO:0016578	histone deubiquitination(GO:0016578)
0.0	0.1	GO:0006975	DNA damage induced protein phosphorylation(GO:0006975)
0.0	0.2	GO:0016572	histone phosphorylation(GO:0016572)
0.0	0.5	GO:0060330	regulation of response to interferon-gamma(GO:0060330) regulation of interferon-gamma-mediated signaling pathway(GO:0060334)
0.0	0.1	GO:0021801	cerebral cortex radial glia guided migration(GO:0021801) layer formation in cerebral cortex(GO:0021819) telencephalon glial cell migration(GO:0022030)
0.0	0.4	GO:0042273	ribosomal large subunit biogenesis(GO:0042273)
0.0	0.0	GO:0034243	negative regulation of DNA-templated transcription, elongation(GO:0032785) regulation of transcription elongation from RNA polymerase II promoter(GO:0034243) negative regulation of transcription elongation from RNA polymerase II promoter(GO:0034244)
0.0	0.1	GO:0032733	positive regulation of interleukin-10 production(GO:0032733)
0.0	0.4	GO:0031581	hemidesmosome assembly(GO:0031581)
0.0	0.2	GO:0006198	cAMP catabolic process(GO:0006198)
0.0	0.1	GO:0017183	peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183)
0.0	0.2	GO:0032055	negative regulation of translation in response to stress(GO:0032055)
0.0	0.1	GO:0032776	DNA methylation on cytosine(GO:0032776) C-5 methylation of cytosine(GO:0090116)
0.0	0.1	GO:0030388	fructose 1,6-bisphosphate metabolic process(GO:0030388)
0.0	0.0	GO:0050849	negative regulation of calcium-mediated signaling(GO:0050849)
0.0	0.1	GO:0042996	regulation of Golgi to plasma membrane protein transport(GO:0042996)
0.0	0.3	GO:0003084	positive regulation of systemic arterial blood pressure(GO:0003084)
0.0	0.1	GO:0002523	leukocyte migration involved in inflammatory response(GO:0002523)
0.0	0.3	GO:0015671	oxygen transport(GO:0015671)
0.0	0.1	GO:0032516	positive regulation of phosphoprotein phosphatase activity(GO:0032516)
0.0	0.4	GO:0006378	mRNA polyadenylation(GO:0006378)
0.0	0.1	GO:0006924	activation-induced cell death of T cells(GO:0006924)
0.0	0.1	GO:0044803	multi-organism membrane organization(GO:0044803)
0.0	0.0	GO:0045292	mRNA cis splicing, via spliceosome(GO:0045292)
0.0	0.2	GO:0060710	chorio-allantoic fusion(GO:0060710)
0.0	0.1	GO:0033235	positive regulation of protein sumoylation(GO:0033235)
0.0	0.1	GO:0032100	positive regulation of response to food(GO:0032097) positive regulation of appetite(GO:0032100)
0.0	0.1	GO:0010624	regulation of Schwann cell proliferation(GO:0010624) negative regulation of Schwann cell proliferation(GO:0010626) negative regulation of glial cell proliferation(GO:0060253)
0.0	0.1	GO:2001234	negative regulation of mitochondrion organization(GO:0010823) negative regulation of release of cytochrome c from mitochondria(GO:0090201) negative regulation of apoptotic signaling pathway(GO:2001234)
0.0	0.1	GO:0048293	isotype switching to IgE isotypes(GO:0048289) regulation of isotype switching to IgE isotypes(GO:0048293)
0.0	0.2	GO:0033631	cell-cell adhesion mediated by integrin(GO:0033631)
0.0	0.1	GO:0070837	dehydroascorbic acid transport(GO:0070837)
0.0	0.1	GO:0008298	intracellular mRNA localization(GO:0008298)
0.0	0.1	GO:0034145	positive regulation of toll-like receptor 4 signaling pathway(GO:0034145)
0.0	0.1	GO:0006189	'de novo' IMP biosynthetic process(GO:0006189)
0.0	0.1	GO:0018125	peptidyl-cysteine methylation(GO:0018125)
0.0	0.1	GO:0018202	peptidyl-histidine phosphorylation(GO:0018106) peptidyl-histidine modification(GO:0018202)
0.0	0.1	GO:0002691	regulation of cellular extravasation(GO:0002691)
0.0	0.1	GO:0060586	multicellular organismal iron ion homeostasis(GO:0060586)
0.0	0.1	GO:0010867	positive regulation of triglyceride biosynthetic process(GO:0010867)
0.0	0.1	GO:0070059	intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress(GO:0070059)
0.0	0.3	GO:0000305	response to oxygen radical(GO:0000305)
0.0	0.4	GO:0015701	bicarbonate transport(GO:0015701)
0.0	0.0	GO:0021529	spinal cord oligodendrocyte cell differentiation(GO:0021529) spinal cord oligodendrocyte cell fate specification(GO:0021530) oligodendrocyte cell fate specification(GO:0021778) glial cell fate specification(GO:0021780)
0.0	0.0	GO:0021797	forebrain anterior/posterior pattern specification(GO:0021797)
0.0	0.1	GO:0048148	behavioral response to cocaine(GO:0048148)
0.0	0.1	GO:0006154	adenosine catabolic process(GO:0006154)
0.0	0.1	GO:0045003	DNA recombinase assembly(GO:0000730) double-strand break repair via synthesis-dependent strand annealing(GO:0045003)
0.0	0.3	GO:0071044	histone mRNA catabolic process(GO:0071044)
0.0	0.1	GO:0051088	PMA-inducible membrane protein ectodomain proteolysis(GO:0051088)
0.0	0.1	GO:0006686	sphingomyelin biosynthetic process(GO:0006686)
0.0	0.1	GO:0003339	regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis(GO:0003339)
0.0	0.3	GO:0042347	negative regulation of NF-kappaB import into nucleus(GO:0042347)
0.0	0.1	GO:0000380	alternative mRNA splicing, via spliceosome(GO:0000380)
0.0	0.1	GO:0042447	hormone catabolic process(GO:0042447)
0.0	0.1	GO:0000089	mitotic metaphase(GO:0000089)
0.0	0.1	GO:0033688	regulation of osteoblast proliferation(GO:0033688)
0.0	0.1	GO:0046469	platelet activating factor metabolic process(GO:0046469)
0.0	0.1	GO:0000098	sulfur amino acid catabolic process(GO:0000098)
0.0	0.1	GO:0031167	rRNA methylation(GO:0031167)
0.0	0.0	GO:0051573	negative regulation of histone H3-K9 methylation(GO:0051573)
0.0	0.1	GO:0015851	nucleobase transport(GO:0015851)
0.0	0.2	GO:0051085	chaperone mediated protein folding requiring cofactor(GO:0051085)
0.0	0.1	GO:0010815	bradykinin catabolic process(GO:0010815)
0.0	0.1	GO:0031507	heterochromatin assembly(GO:0031507) heterochromatin organization(GO:0070828)
0.0	0.3	GO:0031146	SCF-dependent proteasomal ubiquitin-dependent protein catabolic process(GO:0031146)
0.0	0.1	GO:0008053	mitochondrial fusion(GO:0008053)
0.0	0.1	GO:0060528	secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development(GO:0060528)
0.0	0.1	GO:0044380	protein localization to cytoskeleton(GO:0044380) protein localization to microtubule cytoskeleton(GO:0072698)
0.0	0.2	GO:0033523	histone H2B ubiquitination(GO:0033523)
0.0	0.1	GO:0006390	mitochondrial RNA metabolic process(GO:0000959) transcription from mitochondrial promoter(GO:0006390)
0.0	0.2	GO:0014037	Schwann cell differentiation(GO:0014037)
0.0	0.1	GO:0051642	centrosome localization(GO:0051642)
0.0	0.1	GO:0032324	Mo-molybdopterin cofactor biosynthetic process(GO:0006777) Mo-molybdopterin cofactor metabolic process(GO:0019720) molybdopterin cofactor biosynthetic process(GO:0032324) molybdopterin cofactor metabolic process(GO:0043545) prosthetic group metabolic process(GO:0051189)
0.0	0.0	GO:0043374	CD8-positive, alpha-beta T cell activation(GO:0036037) CD8-positive, alpha-beta T cell differentiation(GO:0043374)
0.0	0.0	GO:0032543	mitochondrial translation(GO:0032543)
0.0	0.0	GO:0001743	optic placode formation(GO:0001743)
0.0	0.5	GO:0006904	vesicle docking involved in exocytosis(GO:0006904)
0.0	0.0	GO:2000143	negative regulation of transcription initiation from RNA polymerase II promoter(GO:0060633) negative regulation of DNA-templated transcription, initiation(GO:2000143)
0.0	0.0	GO:0006007	glucose catabolic process(GO:0006007)
0.0	0.0	GO:0010803	regulation of tumor necrosis factor-mediated signaling pathway(GO:0010803)
0.0	0.3	GO:0009083	branched-chain amino acid catabolic process(GO:0009083)
0.0	0.1	GO:0048488	synaptic vesicle recycling(GO:0036465) synaptic vesicle endocytosis(GO:0048488) clathrin-mediated endocytosis(GO:0072583)
0.0	0.1	GO:0043984	histone H4-K16 acetylation(GO:0043984)
0.0	0.0	GO:0002829	negative regulation of type 2 immune response(GO:0002829)
0.0	0.0	GO:0045359	interferon-beta biosynthetic process(GO:0045350) regulation of interferon-beta biosynthetic process(GO:0045357) positive regulation of interferon-beta biosynthetic process(GO:0045359)
0.0	0.1	GO:0045910	negative regulation of DNA recombination(GO:0045910)
0.0	0.2	GO:0043124	negative regulation of I-kappaB kinase/NF-kappaB signaling(GO:0043124)
0.0	0.0	GO:0051489	regulation of filopodium assembly(GO:0051489)
0.0	0.5	GO:0000289	nuclear-transcribed mRNA poly(A) tail shortening(GO:0000289)
0.0	0.1	GO:0032461	positive regulation of protein oligomerization(GO:0032461)
0.0	0.1	GO:0060081	membrane hyperpolarization(GO:0060081)
0.0	0.2	GO:0045197	establishment or maintenance of epithelial cell apical/basal polarity(GO:0045197)
0.0	0.0	GO:0003099	positive regulation of the force of heart contraction by chemical signal(GO:0003099)
0.0	0.0	GO:0009214	cyclic nucleotide catabolic process(GO:0009214)
0.0	0.1	GO:0003100	regulation of systemic arterial blood pressure by endothelin(GO:0003100)
0.0	0.2	GO:0009312	oligosaccharide biosynthetic process(GO:0009312)
0.0	0.1	GO:0010614	negative regulation of cardiac muscle hypertrophy(GO:0010614)
0.0	0.1	GO:0021612	rhombomere 4 development(GO:0021570) cranial nerve structural organization(GO:0021604) facial nerve morphogenesis(GO:0021610) facial nerve structural organization(GO:0021612)
0.0	0.2	GO:0000097	sulfur amino acid biosynthetic process(GO:0000097)
0.0	0.1	GO:0016322	neuron remodeling(GO:0016322)
0.0	0.2	GO:0098927	early endosome to late endosome transport(GO:0045022) vesicle-mediated transport between endosomal compartments(GO:0098927)
0.0	0.2	GO:0021527	spinal cord association neuron differentiation(GO:0021527)
0.0	0.2	GO:0007141	male meiosis I(GO:0007141)
0.0	0.5	GO:0070936	protein K48-linked ubiquitination(GO:0070936)
0.0	0.0	GO:0034391	smooth muscle cell apoptotic process(GO:0034390) regulation of smooth muscle cell apoptotic process(GO:0034391) negative regulation of smooth muscle cell apoptotic process(GO:0034392)
0.0	0.1	GO:1901224	activation of NF-kappaB-inducing kinase activity(GO:0007250) NIK/NF-kappaB signaling(GO:0038061) regulation of NIK/NF-kappaB signaling(GO:1901222) positive regulation of NIK/NF-kappaB signaling(GO:1901224)
0.0	0.1	GO:0035455	response to interferon-alpha(GO:0035455)
0.0	0.0	GO:0002331	pre-B cell allelic exclusion(GO:0002331)
0.0	0.1	GO:0034219	carbohydrate transmembrane transport(GO:0034219)
0.0	0.1	GO:0060023	soft palate development(GO:0060023)
0.0	0.0	GO:0060396	growth hormone receptor signaling pathway(GO:0060396) cellular response to growth hormone stimulus(GO:0071378)
0.0	0.3	GO:1900181	negative regulation of protein import into nucleus(GO:0042308) negative regulation of protein localization to nucleus(GO:1900181) negative regulation of protein import(GO:1904590)
0.0	0.3	GO:0042130	negative regulation of T cell proliferation(GO:0042130)
0.0	0.1	GO:0015015	heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.0	0.0	GO:0002418	immune response to tumor cell(GO:0002418)
0.0	0.4	GO:0008633	obsolete activation of pro-apoptotic gene products(GO:0008633)
0.0	0.1	GO:0032075	positive regulation of nuclease activity(GO:0032075)
0.0	0.0	GO:0030210	heparin biosynthetic process(GO:0030210)
0.0	0.2	GO:0051568	histone H3-K4 methylation(GO:0051568)
0.0	0.0	GO:0046668	retinal cell programmed cell death(GO:0046666) regulation of retinal cell programmed cell death(GO:0046668)
0.0	0.3	GO:0042776	mitochondrial ATP synthesis coupled proton transport(GO:0042776)
0.0	0.1	GO:0006422	aspartyl-tRNA aminoacylation(GO:0006422)
0.0	0.1	GO:0032926	negative regulation of activin receptor signaling pathway(GO:0032926)
0.0	0.1	GO:0006983	ER overload response(GO:0006983)
0.0	0.0	GO:0060999	positive regulation of dendritic spine development(GO:0060999)
0.0	0.1	GO:0002087	regulation of respiratory gaseous exchange by neurological system process(GO:0002087)
0.0	0.1	GO:0031269	pseudopodium assembly(GO:0031269) regulation of pseudopodium assembly(GO:0031272) positive regulation of pseudopodium assembly(GO:0031274)
0.0	0.1	GO:0016188	synaptic vesicle maturation(GO:0016188)
0.0	0.0	GO:0061162	establishment of apical/basal cell polarity(GO:0035089) establishment of monopolar cell polarity(GO:0061162) establishment or maintenance of monopolar cell polarity(GO:0061339)
0.0	0.1	GO:0048617	embryonic foregut morphogenesis(GO:0048617)
0.0	0.1	GO:0043568	positive regulation of insulin-like growth factor receptor signaling pathway(GO:0043568)
0.0	0.2	GO:0032456	endocytic recycling(GO:0032456)
0.0	0.1	GO:0021516	dorsal spinal cord development(GO:0021516)
0.0	0.2	GO:0046519	sphingoid metabolic process(GO:0046519)
0.0	0.0	GO:0042483	negative regulation of odontogenesis(GO:0042483)
0.0	0.0	GO:0070682	proteasome regulatory particle assembly(GO:0070682)
0.0	0.1	GO:0007181	transforming growth factor beta receptor complex assembly(GO:0007181)
0.0	0.1	GO:0001991	regulation of systemic arterial blood pressure by circulatory renin-angiotensin(GO:0001991)
0.0	0.0	GO:0034616	response to laminar fluid shear stress(GO:0034616)
0.0	0.0	GO:0051461	corticotropin secretion(GO:0051458) regulation of corticotropin secretion(GO:0051459) positive regulation of corticotropin secretion(GO:0051461)
0.0	0.1	GO:0006498	N-terminal protein lipidation(GO:0006498)
0.0	0.2	GO:0014046	dopamine secretion(GO:0014046) regulation of dopamine secretion(GO:0014059)
0.0	0.0	GO:0034143	regulation of toll-like receptor 4 signaling pathway(GO:0034143)
0.0	0.1	GO:0016553	base conversion or substitution editing(GO:0016553)
0.0	0.1	GO:1900087	traversing start control point of mitotic cell cycle(GO:0007089) positive regulation of G1/S transition of mitotic cell cycle(GO:1900087) positive regulation of cell cycle G1/S phase transition(GO:1902808)
0.0	0.1	GO:0071391	cellular response to estrogen stimulus(GO:0071391)
0.0	0.1	GO:0015801	aromatic amino acid transport(GO:0015801)
0.0	0.1	GO:0042523	positive regulation of tyrosine phosphorylation of Stat5 protein(GO:0042523)
0.0	0.1	GO:0046476	glycosylceramide biosynthetic process(GO:0046476)
0.0	0.1	GO:0008631	intrinsic apoptotic signaling pathway in response to oxidative stress(GO:0008631) cell death in response to oxidative stress(GO:0036473)
0.0	0.1	GO:0006689	ganglioside catabolic process(GO:0006689)
0.0	0.1	GO:0046015	carbon catabolite regulation of transcription(GO:0045990) regulation of transcription by glucose(GO:0046015)
0.0	0.3	GO:0006997	nucleus organization(GO:0006997)
0.0	0.1	GO:0006513	protein monoubiquitination(GO:0006513)
0.0	0.1	GO:0006269	DNA replication, synthesis of RNA primer(GO:0006269)
0.0	0.1	GO:0045948	positive regulation of translational initiation(GO:0045948)
0.0	0.1	GO:0033962	cytoplasmic mRNA processing body assembly(GO:0033962)
0.0	0.3	GO:0016601	Rac protein signal transduction(GO:0016601)
0.0	0.1	GO:0070536	protein K63-linked deubiquitination(GO:0070536)
0.0	0.0	GO:0072033	renal vesicle formation(GO:0072033)
0.0	0.1	GO:0060088	auditory receptor cell morphogenesis(GO:0002093) auditory receptor cell stereocilium organization(GO:0060088)
0.0	0.0	GO:0061029	eyelid development in camera-type eye(GO:0061029)
0.0	0.1	GO:0046548	retinal rod cell development(GO:0046548)
0.0	0.2	GO:0031648	protein destabilization(GO:0031648)
0.0	0.1	GO:0034501	protein localization to kinetochore(GO:0034501)
0.0	0.1	GO:0051503	adenine nucleotide transport(GO:0051503)
0.0	0.1	GO:0000012	single strand break repair(GO:0000012)
0.0	0.0	GO:0021563	glossopharyngeal nerve development(GO:0021563) glossopharyngeal nerve morphogenesis(GO:0021615)
0.0	0.1	GO:2000114	regulation of establishment of cell polarity(GO:2000114)
0.0	0.0	GO:0007621	negative regulation of female receptivity(GO:0007621)
0.0	0.1	GO:0002475	antigen processing and presentation via MHC class Ib(GO:0002475)
0.0	0.1	GO:0070670	response to interleukin-4(GO:0070670)
0.0	0.0	GO:0010457	centriole-centriole cohesion(GO:0010457)
0.0	0.0	GO:0051594	detection of carbohydrate stimulus(GO:0009730) detection of hexose stimulus(GO:0009732) detection of monosaccharide stimulus(GO:0034287) detection of glucose(GO:0051594)
0.0	0.1	GO:0006516	glycoprotein catabolic process(GO:0006516)
0.0	0.0	GO:0010511	regulation of phosphatidylinositol biosynthetic process(GO:0010511)
0.0	0.0	GO:0048668	collateral sprouting(GO:0048668) regulation of collateral sprouting(GO:0048670)
0.0	0.1	GO:0001510	RNA methylation(GO:0001510)
0.0	0.0	GO:0046880	regulation of follicle-stimulating hormone secretion(GO:0046880)
0.0	0.0	GO:0090047	obsolete positive regulation of transcription regulator activity(GO:0090047)
0.0	0.1	GO:0071542	dopaminergic neuron differentiation(GO:0071542)
0.0	0.2	GO:0032008	positive regulation of TOR signaling(GO:0032008)
0.0	0.0	GO:0046719	intracellular transport of viral protein in host cell(GO:0019060) symbiont intracellular protein transport in host(GO:0030581) regulation by virus of viral protein levels in host cell(GO:0046719) intracellular protein transport in other organism involved in symbiotic interaction(GO:0051708)
0.0	0.1	GO:0090175	Wnt signaling pathway, planar cell polarity pathway(GO:0060071) regulation of establishment of planar polarity(GO:0090175)
0.0	0.0	GO:0032814	regulation of natural killer cell activation(GO:0032814)
0.0	0.2	GO:0002286	T cell activation involved in immune response(GO:0002286)
0.0	0.1	GO:0006614	SRP-dependent cotranslational protein targeting to membrane(GO:0006614)
0.0	0.0	GO:0046951	ketone body biosynthetic process(GO:0046951)
0.0	0.0	GO:0071168	protein localization to chromatin(GO:0071168)
0.0	0.1	GO:0000244	spliceosomal tri-snRNP complex assembly(GO:0000244)
0.0	0.2	GO:0016180	snRNA processing(GO:0016180)
0.0	0.1	GO:0016557	peroxisome membrane biogenesis(GO:0016557)
0.0	0.1	GO:0007064	mitotic sister chromatid cohesion(GO:0007064)
0.0	0.1	GO:0015693	magnesium ion transport(GO:0015693)
0.0	0.2	GO:0051220	cytoplasmic sequestering of protein(GO:0051220)
0.0	0.2	GO:0033540	fatty acid beta-oxidation using acyl-CoA oxidase(GO:0033540)
0.0	0.0	GO:0046607	positive regulation of centrosome cycle(GO:0046607)
0.0	0.1	GO:0006855	drug transmembrane transport(GO:0006855)
0.0	0.0	GO:0006922	obsolete cleavage of lamin involved in execution phase of apoptosis(GO:0006922)
0.0	0.3	GO:0006779	porphyrin-containing compound biosynthetic process(GO:0006779)
0.0	0.1	GO:0009103	lipopolysaccharide biosynthetic process(GO:0009103)
0.0	0.0	GO:0019730	antimicrobial humoral response(GO:0019730) antibacterial humoral response(GO:0019731)
0.0	0.1	GO:0043666	regulation of phosphoprotein phosphatase activity(GO:0043666)
0.0	0.0	GO:0010739	positive regulation of protein kinase A signaling(GO:0010739)
0.0	0.7	GO:0006921	cellular component disassembly involved in execution phase of apoptosis(GO:0006921) execution phase of apoptosis(GO:0097194)
0.0	0.4	GO:0000245	spliceosomal complex assembly(GO:0000245)
0.0	0.0	GO:0060762	regulation of branching involved in mammary gland duct morphogenesis(GO:0060762)
0.0	0.2	GO:0007379	segment specification(GO:0007379)
0.0	0.3	GO:0060135	maternal process involved in female pregnancy(GO:0060135)
0.0	0.0	GO:0050435	beta-amyloid metabolic process(GO:0050435)
0.0	0.0	GO:0048537	mucosal-associated lymphoid tissue development(GO:0048537)
0.0	0.0	GO:0043628	ncRNA 3'-end processing(GO:0043628)
0.0	0.0	GO:0060117	auditory receptor cell development(GO:0060117)
0.0	0.0	GO:0032236	obsolete positive regulation of calcium ion transport via store-operated calcium channel activity(GO:0032236)
0.0	0.1	GO:0015074	DNA integration(GO:0015074)
0.0	0.7	GO:0071166	ribonucleoprotein complex localization(GO:0071166)
0.0	0.5	GO:0006888	ER to Golgi vesicle-mediated transport(GO:0006888)
0.0	0.1	GO:0071941	nitrogen cycle metabolic process(GO:0071941)
0.0	0.0	GO:0006106	fumarate metabolic process(GO:0006106)
0.0	0.0	GO:0055064	cellular chloride ion homeostasis(GO:0030644) chloride ion homeostasis(GO:0055064)
0.0	0.1	GO:0001573	ganglioside metabolic process(GO:0001573)
0.0	0.1	GO:0070493	thrombin receptor signaling pathway(GO:0070493)
0.0	0.0	GO:0007144	female meiosis I(GO:0007144)
0.0	0.3	GO:0005980	glycogen catabolic process(GO:0005980)
0.0	0.0	GO:0010944	negative regulation of transcription by competitive promoter binding(GO:0010944)
0.0	0.1	GO:0046676	negative regulation of insulin secretion(GO:0046676)
0.0	0.0	GO:0035434	copper ion transmembrane transport(GO:0035434)
0.0	0.1	GO:0006528	asparagine metabolic process(GO:0006528)
0.0	0.0	GO:0042088	T-helper 1 type immune response(GO:0042088)
0.0	0.1	GO:0009298	GDP-mannose biosynthetic process(GO:0009298)
0.0	0.2	GO:0007030	Golgi organization(GO:0007030)
0.0	0.1	GO:0007096	regulation of exit from mitosis(GO:0007096)
0.0	0.0	GO:0046884	follicle-stimulating hormone secretion(GO:0046884)
0.0	0.0	GO:0015917	aminophospholipid transport(GO:0015917)
0.0	0.1	GO:0019883	antigen processing and presentation of endogenous peptide antigen(GO:0002483) antigen processing and presentation of endogenous antigen(GO:0019883) antigen processing and presentation of endogenous peptide antigen via MHC class I(GO:0019885)
0.0	0.0	GO:0045943	positive regulation of transcription from RNA polymerase I promoter(GO:0045943)
0.0	0.0	GO:0046185	aldehyde catabolic process(GO:0046185)
0.0	0.1	GO:0042769	DNA damage response, detection of DNA damage(GO:0042769)
0.0	0.1	GO:0032410	negative regulation of transporter activity(GO:0032410)
0.0	0.0	GO:0045657	positive regulation of monocyte differentiation(GO:0045657)
0.0	0.0	GO:0034626	fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.0	0.2	GO:0045814	negative regulation of gene expression, epigenetic(GO:0045814)
0.0	0.6	GO:0072431	DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest(GO:0006977) signal transduction involved in cell cycle checkpoint(GO:0072395) signal transduction involved in DNA integrity checkpoint(GO:0072401) signal transduction involved in mitotic cell cycle checkpoint(GO:0072413) signal transduction involved in DNA damage checkpoint(GO:0072422) signal transduction involved in mitotic G1 DNA damage checkpoint(GO:0072431) intracellular signal transduction involved in G1 DNA damage checkpoint(GO:1902400) signal transduction involved in mitotic DNA damage checkpoint(GO:1902402) signal transduction involved in mitotic DNA integrity checkpoint(GO:1902403)
0.0	0.2	GO:1904668	positive regulation of ubiquitin protein ligase activity(GO:1904668)
0.0	0.1	GO:0006449	regulation of translational termination(GO:0006449)
0.0	0.1	GO:0098657	neurotransmitter uptake(GO:0001504) import into cell(GO:0098657)
0.0	0.0	GO:0001302	replicative cell aging(GO:0001302)
0.0	0.2	GO:0009303	rRNA transcription(GO:0009303)
0.0	0.1	GO:0032784	regulation of DNA-templated transcription, elongation(GO:0032784)
0.0	0.4	GO:0022616	DNA strand elongation(GO:0022616)
0.0	0.0	GO:1904035	endothelial cell apoptotic process(GO:0072577) epithelial cell apoptotic process(GO:1904019) regulation of epithelial cell apoptotic process(GO:1904035) regulation of endothelial cell apoptotic process(GO:2000351)
0.0	0.0	GO:0033151	V(D)J recombination(GO:0033151)
0.0	0.1	GO:0001829	trophectodermal cell differentiation(GO:0001829)
0.0	0.0	GO:0060017	parathyroid gland development(GO:0060017)
0.0	0.0	GO:0032459	regulation of protein oligomerization(GO:0032459)
0.0	0.0	GO:0042501	serine phosphorylation of STAT protein(GO:0042501)
0.0	0.2	GO:0035637	transmission of nerve impulse(GO:0019226) multicellular organismal signaling(GO:0035637)
0.0	0.1	GO:0001514	selenocysteine incorporation(GO:0001514) translational readthrough(GO:0006451)
0.0	0.0	GO:0040009	regulation of growth rate(GO:0040009)
0.0	0.2	GO:0007339	binding of sperm to zona pellucida(GO:0007339)
0.0	0.0	GO:0001782	B cell homeostasis(GO:0001782)
0.0	0.0	GO:0060968	regulation of gene silencing(GO:0060968)
0.0	0.1	GO:0042987	amyloid precursor protein catabolic process(GO:0042987)
0.0	0.0	GO:0030240	skeletal muscle thin filament assembly(GO:0030240)
0.0	0.0	GO:0060972	left/right pattern formation(GO:0060972)
0.0	0.0	GO:0006681	galactosylceramide metabolic process(GO:0006681)
0.0	0.0	GO:0072215	regulation of metanephros development(GO:0072215)
0.0	0.0	GO:0042640	anagen(GO:0042640)
0.0	0.1	GO:0006607	NLS-bearing protein import into nucleus(GO:0006607)
0.0	0.1	GO:0072595	maintenance of protein localization in organelle(GO:0072595)
0.0	0.1	GO:0031571	mitotic G1 DNA damage checkpoint(GO:0031571) G1 DNA damage checkpoint(GO:0044783) mitotic G1/S transition checkpoint(GO:0044819)
0.0	0.0	GO:0002327	immature B cell differentiation(GO:0002327) pre-B cell differentiation(GO:0002329)
0.0	0.1	GO:0007076	mitotic chromosome condensation(GO:0007076)
0.0	0.0	GO:0070092	glucagon secretion(GO:0070091) regulation of glucagon secretion(GO:0070092)
0.0	0.0	GO:0045078	positive regulation of interferon-gamma biosynthetic process(GO:0045078)
0.0	0.0	GO:0048024	regulation of mRNA splicing, via spliceosome(GO:0048024)
0.0	0.0	GO:0009822	alkaloid catabolic process(GO:0009822)
0.0	0.0	GO:0010919	regulation of inositol phosphate biosynthetic process(GO:0010919)
0.0	0.0	GO:0010822	positive regulation of mitochondrion organization(GO:0010822) regulation of release of cytochrome c from mitochondria(GO:0090199) positive regulation of release of cytochrome c from mitochondria(GO:0090200) regulation of apoptotic signaling pathway(GO:2001233) positive regulation of apoptotic signaling pathway(GO:2001235)
0.0	0.0	GO:0006303	double-strand break repair via nonhomologous end joining(GO:0006303)
0.0	0.0	GO:0030952	establishment or maintenance of cytoskeleton polarity(GO:0030952)
0.0	0.0	GO:0060708	spongiotrophoblast differentiation(GO:0060708)
0.0	0.1	GO:0007158	neuron cell-cell adhesion(GO:0007158)
0.0	0.1	GO:0006744	ubiquinone metabolic process(GO:0006743) ubiquinone biosynthetic process(GO:0006744)
0.0	0.0	GO:0042117	monocyte activation(GO:0042117)
0.0	0.0	GO:0043171	peptide catabolic process(GO:0043171)
0.0	0.0	GO:0006379	mRNA cleavage(GO:0006379)
0.0	0.0	GO:0009648	photoperiodism(GO:0009648)
0.0	0.0	GO:0032958	inositol phosphate biosynthetic process(GO:0032958)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	0.5	GO:0031235	intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.1	1.0	GO:0001891	phagocytic cup(GO:0001891)
0.1	0.3	GO:0032591	dendritic spine membrane(GO:0032591)
0.1	0.4	GO:0000300	obsolete peripheral to membrane of membrane fraction(GO:0000300)
0.1	0.3	GO:0032444	activin responsive factor complex(GO:0032444)
0.1	0.4	GO:0005658	alpha DNA polymerase:primase complex(GO:0005658)
0.1	0.2	GO:0032045	guanyl-nucleotide exchange factor complex(GO:0032045)
0.1	0.5	GO:0043190	ATP-binding cassette (ABC) transporter complex(GO:0043190)
0.1	0.3	GO:0033256	I-kappaB/NF-kappaB complex(GO:0033256)
0.1	0.2	GO:0000942	condensed nuclear chromosome outer kinetochore(GO:0000942)
0.1	0.7	GO:0035631	CD40 receptor complex(GO:0035631)
0.1	0.2	GO:0005896	interleukin-6 receptor complex(GO:0005896)
0.1	0.2	GO:0031371	ubiquitin conjugating enzyme complex(GO:0031371)
0.1	0.1	GO:0070937	CRD-mediated mRNA stability complex(GO:0070937)
0.1	0.6	GO:0017119	Golgi transport complex(GO:0017119)
0.1	0.3	GO:0042382	paraspeckles(GO:0042382)
0.1	0.2	GO:0005826	actomyosin contractile ring(GO:0005826) contractile ring(GO:0070938)
0.1	0.4	GO:0061200	clathrin-sculpted gamma-aminobutyric acid transport vesicle(GO:0061200) clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane(GO:0061202)
0.1	0.2	GO:0034992	microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.0	0.2	GO:0071204	histone pre-mRNA 3'end processing complex(GO:0071204)
0.0	0.2	GO:0005797	Golgi medial cisterna(GO:0005797)
0.0	0.1	GO:0031932	TORC2 complex(GO:0031932)
0.0	0.4	GO:0016585	obsolete chromatin remodeling complex(GO:0016585)
0.0	0.1	GO:0032590	dendrite membrane(GO:0032590)
0.0	0.4	GO:0010494	cytoplasmic stress granule(GO:0010494)
0.0	0.3	GO:0019773	proteasome core complex, alpha-subunit complex(GO:0019773)
0.0	0.1	GO:0070022	transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.0	0.1	GO:0014731	spectrin-associated cytoskeleton(GO:0014731)
0.0	0.4	GO:0071564	npBAF complex(GO:0071564)
0.0	0.2	GO:0005827	polar microtubule(GO:0005827)
0.0	0.5	GO:0033276	transcription factor TFTC complex(GO:0033276)
0.0	0.1	GO:0042105	alpha-beta T cell receptor complex(GO:0042105)
0.0	0.2	GO:0016514	SWI/SNF complex(GO:0016514)
0.0	0.1	GO:0072487	MSL complex(GO:0072487)
0.0	0.3	GO:0042598	obsolete vesicular fraction(GO:0042598)
0.0	0.2	GO:0044224	juxtaparanode region of axon(GO:0044224)
0.0	0.1	GO:0005850	eukaryotic translation initiation factor 2 complex(GO:0005850)
0.0	0.1	GO:0001740	Barr body(GO:0001740)
0.0	0.8	GO:0019005	SCF ubiquitin ligase complex(GO:0019005)
0.0	0.3	GO:0016342	catenin complex(GO:0016342)
0.0	0.2	GO:0070419	nonhomologous end joining complex(GO:0070419)
0.0	1.0	GO:0005626	obsolete insoluble fraction(GO:0005626)
0.0	0.2	GO:0070688	MLL5-L complex(GO:0070688)
0.0	0.3	GO:0001772	immunological synapse(GO:0001772)
0.0	0.1	GO:0032777	Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.0	0.2	GO:0045239	tricarboxylic acid cycle enzyme complex(GO:0045239)
0.0	0.1	GO:0031088	platelet dense granule membrane(GO:0031088)
0.0	0.4	GO:0005852	eukaryotic translation initiation factor 3 complex(GO:0005852)
0.0	0.5	GO:0046658	anchored component of plasma membrane(GO:0046658)
0.0	0.3	GO:0005942	phosphatidylinositol 3-kinase complex(GO:0005942)
0.0	0.2	GO:0045261	proton-transporting ATP synthase complex, catalytic core F(1)(GO:0045261)
0.0	0.2	GO:0031463	Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0	0.1	GO:0035098	ESC/E(Z) complex(GO:0035098)
0.0	0.2	GO:0005847	mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.0	0.2	GO:0046581	intercellular canaliculus(GO:0046581)
0.0	0.2	GO:0008250	oligosaccharyltransferase complex(GO:0008250)
0.0	0.1	GO:0005945	6-phosphofructokinase complex(GO:0005945)
0.0	0.2	GO:0030877	beta-catenin destruction complex(GO:0030877)
0.0	0.3	GO:0045120	pronucleus(GO:0045120)
0.0	0.1	GO:0044453	integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229) nuclear membrane part(GO:0044453)
0.0	0.1	GO:0016589	NURF complex(GO:0016589)
0.0	0.4	GO:0000159	protein phosphatase type 2A complex(GO:0000159)
0.0	0.1	GO:0031305	integral component of mitochondrial inner membrane(GO:0031305)
0.0	0.1	GO:0001931	uropod(GO:0001931) cell trailing edge(GO:0031254)
0.0	0.1	GO:0046696	lipopolysaccharide receptor complex(GO:0046696)
0.0	0.0	GO:0031904	endosome lumen(GO:0031904)
0.0	0.4	GO:0005892	acetylcholine-gated channel complex(GO:0005892)
0.0	0.0	GO:0030686	90S preribosome(GO:0030686)
0.0	0.1	GO:0005863	striated muscle myosin thick filament(GO:0005863)
0.0	0.1	GO:0032449	CBM complex(GO:0032449)
0.0	0.1	GO:0005677	chromatin silencing complex(GO:0005677)
0.0	0.0	GO:0005849	mRNA cleavage factor complex(GO:0005849)
0.0	0.2	GO:0032039	integrator complex(GO:0032039)
0.0	0.3	GO:0045334	clathrin-coated endocytic vesicle(GO:0045334)
0.0	0.7	GO:0030175	filopodium(GO:0030175)
0.0	0.2	GO:0032838	cell projection cytoplasm(GO:0032838)
0.0	0.6	GO:0042645	mitochondrial nucleoid(GO:0042645)
0.0	0.1	GO:0008290	F-actin capping protein complex(GO:0008290)
0.0	0.2	GO:0031105	septin complex(GO:0031105) septin cytoskeleton(GO:0032156)
0.0	0.6	GO:0005876	spindle microtubule(GO:0005876)
0.0	0.1	GO:0071986	Ragulator complex(GO:0071986)
0.0	0.3	GO:0016328	lateral plasma membrane(GO:0016328)
0.0	0.1	GO:0030061	mitochondrial crista(GO:0030061)
0.0	0.1	GO:0032585	multivesicular body membrane(GO:0032585)
0.0	0.1	GO:0048500	signal recognition particle, endoplasmic reticulum targeting(GO:0005786) signal recognition particle(GO:0048500)
0.0	0.0	GO:0032133	chromosome passenger complex(GO:0032133)
0.0	0.3	GO:0016581	NuRD complex(GO:0016581) CHD-type complex(GO:0090545) nuclear transcriptional repressor complex(GO:0090568)
0.0	0.2	GO:0008278	cohesin complex(GO:0008278)
0.0	0.0	GO:0016533	cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533)
0.0	0.2	GO:0031080	nuclear pore outer ring(GO:0031080)
0.0	0.3	GO:0000178	exosome (RNase complex)(GO:0000178)
0.0	0.1	GO:0008274	gamma-tubulin large complex(GO:0000931) gamma-tubulin ring complex(GO:0008274)
0.0	0.1	GO:0070776	H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.0	0.1	GO:0042101	T cell receptor complex(GO:0042101)
0.0	0.1	GO:0000791	euchromatin(GO:0000791)
0.0	0.1	GO:0016471	vacuolar proton-transporting V-type ATPase complex(GO:0016471)
0.0	0.0	GO:0070545	PeBoW complex(GO:0070545)
0.0	0.3	GO:0005605	basal lamina(GO:0005605)
0.0	1.5	GO:0000151	ubiquitin ligase complex(GO:0000151)
0.0	0.3	GO:0000932	cytoplasmic mRNA processing body(GO:0000932)
0.0	0.1	GO:0031519	PcG protein complex(GO:0031519)
0.0	0.1	GO:0034045	pre-autophagosomal structure membrane(GO:0034045)
0.0	0.1	GO:0000276	mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.0	0.1	GO:0001741	XY body(GO:0001741)
0.0	0.1	GO:0030121	AP-1 adaptor complex(GO:0030121)
0.0	0.5	GO:0022625	cytosolic large ribosomal subunit(GO:0022625)
0.0	0.2	GO:0005762	organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.0	0.1	GO:0045281	mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)(GO:0005749) succinate dehydrogenase complex (ubiquinone)(GO:0045257) respiratory chain complex II(GO:0045273) succinate dehydrogenase complex(GO:0045281) fumarate reductase complex(GO:0045283)
0.0	0.0	GO:0000137	Golgi cis cisterna(GO:0000137)
0.0	0.1	GO:0005671	Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
0.0	0.1	GO:0016602	CCAAT-binding factor complex(GO:0016602)
0.0	0.8	GO:0005643	nuclear pore(GO:0005643)
0.0	0.2	GO:0032420	stereocilium(GO:0032420)
0.0	0.1	GO:0005663	DNA replication factor C complex(GO:0005663)
0.0	0.1	GO:0070695	FHF complex(GO:0070695)
0.0	0.1	GO:0000444	MIS12/MIND type complex(GO:0000444)
0.0	0.4	GO:0016592	mediator complex(GO:0016592)
0.0	0.3	GO:0055038	recycling endosome membrane(GO:0055038)
0.0	0.1	GO:0045263	proton-transporting ATP synthase complex, coupling factor F(o)(GO:0045263)
0.0	0.3	GO:0055037	recycling endosome(GO:0055037)
0.0	0.1	GO:0005838	proteasome regulatory particle(GO:0005838)
0.0	0.0	GO:0031082	BLOC complex(GO:0031082) BLOC-1 complex(GO:0031083)
0.0	0.1	GO:0097425	smooth endoplasmic reticulum membrane(GO:0030868) smooth endoplasmic reticulum part(GO:0097425)
0.0	0.2	GO:0005763	organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.0	0.3	GO:0005921	gap junction(GO:0005921)
0.0	0.0	GO:0032009	early phagosome(GO:0032009)
0.0	0.1	GO:0002102	podosome(GO:0002102)
0.0	0.1	GO:0070652	HAUS complex(GO:0070652)
0.0	0.0	GO:0042583	chromaffin granule(GO:0042583) chromaffin granule membrane(GO:0042584)
0.0	0.0	GO:0000138	Golgi trans cisterna(GO:0000138)
0.0	0.0	GO:0033268	node of Ranvier(GO:0033268)
0.0	0.1	GO:0000796	condensin complex(GO:0000796)
0.0	0.5	GO:0030173	integral component of Golgi membrane(GO:0030173)
0.0	0.0	GO:0031233	intrinsic component of external side of plasma membrane(GO:0031233)
0.0	0.2	GO:0030131	clathrin adaptor complex(GO:0030131)
0.0	0.1	GO:0032040	small-subunit processome(GO:0032040)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	0.5	GO:0046935	1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.1	0.4	GO:0016309	1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
0.1	1.3	GO:0016274	arginine N-methyltransferase activity(GO:0016273) protein-arginine N-methyltransferase activity(GO:0016274)
0.1	0.5	GO:0030284	estrogen receptor activity(GO:0030284)
0.1	0.3	GO:0005017	platelet-derived growth factor-activated receptor activity(GO:0005017)
0.1	0.3	GO:0004351	glutamate decarboxylase activity(GO:0004351)
0.1	0.4	GO:0034237	protein kinase A regulatory subunit binding(GO:0034237)
0.1	0.7	GO:0034713	type I transforming growth factor beta receptor binding(GO:0034713)
0.1	0.4	GO:0004774	succinate-CoA ligase activity(GO:0004774)
0.1	0.3	GO:0016842	amidine-lyase activity(GO:0016842)
0.1	0.3	GO:0004525	ribonuclease III activity(GO:0004525) double-stranded RNA-specific ribonuclease activity(GO:0032296)
0.1	0.1	GO:0005527	macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.1	0.3	GO:0008510	sodium:bicarbonate symporter activity(GO:0008510)
0.1	0.2	GO:0005127	ciliary neurotrophic factor receptor binding(GO:0005127)
0.1	0.2	GO:0042910	xenobiotic-transporting ATPase activity(GO:0008559) xenobiotic transporter activity(GO:0042910)
0.1	0.3	GO:0016721	superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
0.1	0.2	GO:0008454	alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.1	0.2	GO:0034236	protein kinase A catalytic subunit binding(GO:0034236)
0.1	0.4	GO:0043422	protein kinase B binding(GO:0043422)
0.1	0.4	GO:0090599	alpha-glucosidase activity(GO:0090599)
0.1	0.2	GO:0004706	JUN kinase kinase kinase activity(GO:0004706)
0.1	0.3	GO:0034452	dynactin binding(GO:0034452)
0.1	0.2	GO:0050265	RNA uridylyltransferase activity(GO:0050265)
0.1	0.2	GO:0043175	RNA polymerase core enzyme binding(GO:0043175)
0.1	0.2	GO:0004311	farnesyltranstransferase activity(GO:0004311)
0.1	0.2	GO:0047238	glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity(GO:0047238)
0.1	0.3	GO:0070577	lysine-acetylated histone binding(GO:0070577)
0.1	0.5	GO:0034593	phosphatidylinositol bisphosphate phosphatase activity(GO:0034593)
0.1	0.2	GO:0004477	methenyltetrahydrofolate cyclohydrolase activity(GO:0004477)
0.1	0.7	GO:0005095	GTPase inhibitor activity(GO:0005095)
0.1	0.2	GO:0033691	sialic acid binding(GO:0033691)
0.1	0.8	GO:0004697	protein kinase C activity(GO:0004697)
0.1	0.2	GO:0004677	DNA-dependent protein kinase activity(GO:0004677)
0.1	0.4	GO:0004437	obsolete inositol or phosphatidylinositol phosphatase activity(GO:0004437)
0.0	0.4	GO:0030332	cyclin binding(GO:0030332)
0.0	0.2	GO:0030229	very-low-density lipoprotein particle receptor activity(GO:0030229)
0.0	0.3	GO:0004691	cAMP-dependent protein kinase activity(GO:0004691)
0.0	0.4	GO:0099604	calcium-release channel activity(GO:0015278) ligand-gated calcium channel activity(GO:0099604)
0.0	0.1	GO:0050815	phosphoserine binding(GO:0050815)
0.0	0.5	GO:0003993	acid phosphatase activity(GO:0003993)
0.0	0.4	GO:0003785	actin monomer binding(GO:0003785)
0.0	0.2	GO:0015355	secondary active monocarboxylate transmembrane transporter activity(GO:0015355)
0.0	0.2	GO:0008526	phosphatidylinositol transporter activity(GO:0008526)
0.0	0.1	GO:0003726	double-stranded RNA adenosine deaminase activity(GO:0003726)
0.0	0.2	GO:0004322	ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.0	0.2	GO:0050897	cobalt ion binding(GO:0050897)
0.0	0.6	GO:0030159	receptor signaling complex scaffold activity(GO:0030159)
0.0	0.3	GO:0070410	co-SMAD binding(GO:0070410)
0.0	0.3	GO:0015271	outward rectifier potassium channel activity(GO:0015271)
0.0	0.1	GO:0015038	glutathione disulfide oxidoreductase activity(GO:0015038)
0.0	0.8	GO:0005164	tumor necrosis factor receptor binding(GO:0005164)
0.0	0.1	GO:0043184	vascular endothelial growth factor receptor 2 binding(GO:0043184)
0.0	0.2	GO:0004740	pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.0	0.1	GO:0001591	dopamine neurotransmitter receptor activity, coupled via Gi/Go(GO:0001591)
0.0	0.1	GO:0016882	cyclo-ligase activity(GO:0016882)
0.0	0.2	GO:0050733	RS domain binding(GO:0050733)
0.0	0.1	GO:0019166	trans-2-enoyl-CoA reductase (NADPH) activity(GO:0019166)
0.0	0.1	GO:0005176	ErbB-2 class receptor binding(GO:0005176)
0.0	0.1	GO:0004886	9-cis retinoic acid receptor activity(GO:0004886)
0.0	0.2	GO:0008079	translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079)
0.0	0.1	GO:0019870	potassium channel inhibitor activity(GO:0019870)
0.0	0.0	GO:0046975	histone methyltransferase activity (H3-K36 specific)(GO:0046975)
0.0	0.3	GO:0016922	ligand-dependent nuclear receptor binding(GO:0016922)
0.0	0.2	GO:0051018	protein kinase A binding(GO:0051018)
0.0	0.4	GO:0016846	carbon-sulfur lyase activity(GO:0016846)
0.0	0.3	GO:0048531	beta-1,3-galactosyltransferase activity(GO:0048531)
0.0	0.1	GO:0016004	phospholipase activator activity(GO:0016004)
0.0	0.2	GO:0008649	rRNA methyltransferase activity(GO:0008649)
0.0	0.9	GO:0003725	double-stranded RNA binding(GO:0003725)
0.0	0.1	GO:0003886	DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.0	0.1	GO:0005094	Rho GDP-dissociation inhibitor activity(GO:0005094)
0.0	0.1	GO:0043024	ribosomal small subunit binding(GO:0043024)
0.0	0.6	GO:0003746	translation elongation factor activity(GO:0003746)
0.0	0.3	GO:0016493	C-C chemokine receptor activity(GO:0016493)
0.0	0.1	GO:0036002	pre-mRNA binding(GO:0036002)
0.0	0.1	GO:0005134	interleukin-2 receptor binding(GO:0005134)
0.0	1.5	GO:0005070	SH3/SH2 adaptor activity(GO:0005070)
0.0	0.2	GO:0017070	U6 snRNA binding(GO:0017070)
0.0	0.3	GO:0046875	ephrin receptor binding(GO:0046875)
0.0	0.1	GO:0019911	structural constituent of myelin sheath(GO:0019911)
0.0	0.1	GO:0033300	dehydroascorbic acid transporter activity(GO:0033300)
0.0	0.1	GO:0005049	nuclear export signal receptor activity(GO:0005049)
0.0	0.1	GO:0030375	thyroid hormone receptor coactivator activity(GO:0030375)
0.0	0.4	GO:0008171	O-methyltransferase activity(GO:0008171)
0.0	0.1	GO:0008486	diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486)
0.0	0.1	GO:0005007	fibroblast growth factor-activated receptor activity(GO:0005007)
0.0	0.2	GO:0005068	transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.0	0.2	GO:0008494	translation activator activity(GO:0008494)
0.0	0.1	GO:0000268	peroxisome targeting sequence binding(GO:0000268)
0.0	0.2	GO:1900750	glutathione binding(GO:0043295) oligopeptide binding(GO:1900750)
0.0	0.1	GO:0015379	potassium:chloride symporter activity(GO:0015379)
0.0	0.1	GO:0005131	growth hormone receptor binding(GO:0005131)
0.0	0.2	GO:0004579	dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.0	0.9	GO:0004402	histone acetyltransferase activity(GO:0004402)
0.0	0.6	GO:0002039	p53 binding(GO:0002039)
0.0	0.2	GO:0015205	nucleobase transmembrane transporter activity(GO:0015205)
0.0	0.1	GO:0016941	natriuretic peptide receptor activity(GO:0016941)
0.0	0.2	GO:0050780	dopamine receptor binding(GO:0050780)
0.0	0.3	GO:0046625	sphingolipid binding(GO:0046625)
0.0	0.2	GO:0031491	nucleosome binding(GO:0031491)
0.0	0.2	GO:0008889	glycerophosphodiester phosphodiesterase activity(GO:0008889)
0.0	0.1	GO:0031628	opioid receptor binding(GO:0031628)
0.0	0.1	GO:0003691	double-stranded telomeric DNA binding(GO:0003691)
0.0	0.1	GO:0003828	alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.0	0.7	GO:0001104	RNA polymerase II transcription cofactor activity(GO:0001104)
0.0	0.1	GO:0003872	6-phosphofructokinase activity(GO:0003872)
0.0	0.2	GO:0005123	death receptor binding(GO:0005123)
0.0	0.1	GO:0008174	mRNA methyltransferase activity(GO:0008174)
0.0	0.1	GO:0015216	adenine nucleotide transmembrane transporter activity(GO:0000295) purine nucleotide transmembrane transporter activity(GO:0015216)
0.0	0.1	GO:0070273	phosphatidylinositol-4-phosphate binding(GO:0070273)
0.0	0.4	GO:0004889	acetylcholine-activated cation-selective channel activity(GO:0004889)
0.0	0.1	GO:0015925	galactosidase activity(GO:0015925)
0.0	0.1	GO:0031996	thioesterase binding(GO:0031996)
0.0	0.2	GO:0016595	glutamate binding(GO:0016595)
0.0	0.3	GO:0042288	MHC class I protein binding(GO:0042288)
0.0	0.1	GO:0016417	S-acyltransferase activity(GO:0016417)
0.0	0.1	GO:0055106	ligase regulator activity(GO:0055103) ubiquitin-protein transferase regulator activity(GO:0055106)
0.0	0.1	GO:0005025	transforming growth factor beta receptor activity, type I(GO:0005025)
0.0	0.2	GO:0034739	histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041) histone deacetylase activity (H4-K16 specific)(GO:0034739) NAD-dependent histone deacetylase activity (H4-K16 specific)(GO:0046970)
0.0	0.1	GO:0004911	interleukin-2 receptor activity(GO:0004911)
0.0	0.1	GO:0004127	cytidylate kinase activity(GO:0004127)
0.0	0.1	GO:0046404	ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity(GO:0046404) polydeoxyribonucleotide kinase activity(GO:0051733) ATP-dependent polynucleotide kinase activity(GO:0051734)
0.0	0.2	GO:0015924	mannosyl-oligosaccharide mannosidase activity(GO:0015924)
0.0	0.2	GO:0003906	DNA-(apurinic or apyrimidinic site) lyase activity(GO:0003906)
0.0	0.3	GO:0043027	cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.0	0.1	GO:0004591	oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591)
0.0	0.1	GO:0004616	phosphogluconate dehydrogenase (decarboxylating) activity(GO:0004616)
0.0	0.1	GO:0032135	DNA insertion or deletion binding(GO:0032135)
0.0	0.1	GO:0003917	DNA topoisomerase type I activity(GO:0003917)
0.0	0.0	GO:0004045	aminoacyl-tRNA hydrolase activity(GO:0004045)
0.0	0.2	GO:0030742	GTP-dependent protein binding(GO:0030742)
0.0	0.1	GO:0015252	hydrogen ion channel activity(GO:0015252)
0.0	0.1	GO:0004815	aspartate-tRNA ligase activity(GO:0004815)
0.0	0.3	GO:0004143	diacylglycerol kinase activity(GO:0004143)
0.0	0.0	GO:0004952	dopamine neurotransmitter receptor activity(GO:0004952)
0.0	0.2	GO:0051721	protein phosphatase 2A binding(GO:0051721)
0.0	0.1	GO:0043539	protein serine/threonine kinase activator activity(GO:0043539)
0.0	0.7	GO:0003755	peptidyl-prolyl cis-trans isomerase activity(GO:0003755)
0.0	0.1	GO:0004000	adenosine deaminase activity(GO:0004000)
0.0	0.2	GO:0016896	exoribonuclease activity, producing 5'-phosphomonoesters(GO:0016896)
0.0	0.1	GO:0016423	tRNA (guanine) methyltransferase activity(GO:0016423)
0.0	0.1	GO:0008821	crossover junction endodeoxyribonuclease activity(GO:0008821)
0.0	0.6	GO:0004629	phospholipase C activity(GO:0004629)
0.0	0.3	GO:0005344	oxygen transporter activity(GO:0005344)
0.0	0.1	GO:0016494	C-X-C chemokine receptor activity(GO:0016494)
0.0	0.0	GO:0052743	inositol tetrakisphosphate phosphatase activity(GO:0052743)
0.0	0.1	GO:0008420	CTD phosphatase activity(GO:0008420)
0.0	0.1	GO:0015288	porin activity(GO:0015288)
0.0	0.1	GO:0008187	poly-pyrimidine tract binding(GO:0008187)
0.0	0.3	GO:0008601	protein phosphatase type 2A regulator activity(GO:0008601)
0.0	0.3	GO:0043621	protein self-association(GO:0043621)
0.0	0.1	GO:0004476	mannose-6-phosphate isomerase activity(GO:0004476)
0.0	0.1	GO:0003985	acetyl-CoA C-acetyltransferase activity(GO:0003985)
0.0	0.1	GO:0008312	7S RNA binding(GO:0008312)
0.0	0.1	GO:0005381	iron ion transmembrane transporter activity(GO:0005381)
0.0	0.1	GO:0008140	cAMP response element binding protein binding(GO:0008140)
0.0	0.1	GO:0017049	GTP-Rho binding(GO:0017049)
0.0	0.2	GO:0031593	polyubiquitin binding(GO:0031593)
0.0	0.1	GO:0000064	L-ornithine transmembrane transporter activity(GO:0000064)
0.0	0.4	GO:0003950	NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.0	0.1	GO:0003964	telomerase activity(GO:0003720) RNA-directed DNA polymerase activity(GO:0003964)
0.0	0.2	GO:0005487	nucleocytoplasmic transporter activity(GO:0005487)
0.0	0.0	GO:0050510	N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity(GO:0050510)
0.0	0.4	GO:0016831	carboxy-lyase activity(GO:0016831)
0.0	0.1	GO:0005092	GDP-dissociation inhibitor activity(GO:0005092)
0.0	0.1	GO:0004459	L-lactate dehydrogenase activity(GO:0004459)
0.0	0.5	GO:0004177	aminopeptidase activity(GO:0004177)
0.0	0.1	GO:0016308	1-phosphatidylinositol-4-phosphate 5-kinase activity(GO:0016308)
0.0	0.0	GO:0004332	fructose-bisphosphate aldolase activity(GO:0004332)
0.0	0.0	GO:0043142	single-stranded DNA-dependent ATPase activity(GO:0043142)
0.0	0.1	GO:0051920	peroxiredoxin activity(GO:0051920)
0.0	0.1	GO:0004176	ATP-dependent peptidase activity(GO:0004176)
0.0	0.0	GO:0033558	protein deacetylase activity(GO:0033558)
0.0	0.2	GO:0043499	obsolete eukaryotic cell surface binding(GO:0043499)
0.0	0.1	GO:0008273	calcium, potassium:sodium antiporter activity(GO:0008273)
0.0	0.1	GO:0048018	receptor agonist activity(GO:0048018)
0.0	0.9	GO:0044389	ubiquitin protein ligase binding(GO:0031625) ubiquitin-like protein ligase binding(GO:0044389)
0.0	0.1	GO:0016668	oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor(GO:0016668)
0.0	0.0	GO:0031702	angiotensin receptor binding(GO:0031701) type 1 angiotensin receptor binding(GO:0031702)
0.0	0.1	GO:0070412	R-SMAD binding(GO:0070412)
0.0	0.4	GO:0017048	Rho GTPase binding(GO:0017048)
0.0	0.1	GO:0060590	ATPase regulator activity(GO:0060590)
0.0	0.0	GO:0003896	DNA primase activity(GO:0003896)
0.0	0.0	GO:0004946	bombesin receptor activity(GO:0004946)
0.0	0.1	GO:0017176	phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.0	0.1	GO:0004652	polynucleotide adenylyltransferase activity(GO:0004652)
0.0	0.4	GO:0004693	cyclin-dependent protein serine/threonine kinase activity(GO:0004693) cyclin-dependent protein kinase activity(GO:0097472)
0.0	0.1	GO:0016854	racemase and epimerase activity(GO:0016854)
0.0	0.1	GO:0003689	DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.0	0.1	GO:0016670	oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor(GO:0016670)
0.0	0.0	GO:0003836	beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.0	0.1	GO:0017025	TBP-class protein binding(GO:0017025)
0.0	0.1	GO:0005375	copper ion transmembrane transporter activity(GO:0005375)
0.0	0.0	GO:0015562	efflux transmembrane transporter activity(GO:0015562)
0.0	0.0	GO:0070548	L-glutamine aminotransferase activity(GO:0070548)
0.0	0.0	GO:0016151	nickel cation binding(GO:0016151)
0.0	0.1	GO:0050700	CARD domain binding(GO:0050700)
0.0	0.1	GO:0000104	succinate dehydrogenase activity(GO:0000104)
0.0	0.3	GO:0004298	threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.0	0.1	GO:0004427	inorganic diphosphatase activity(GO:0004427)
0.0	0.1	GO:0015651	quaternary ammonium group transmembrane transporter activity(GO:0015651)
0.0	0.2	GO:0004016	adenylate cyclase activity(GO:0004016)
0.0	0.2	GO:0005452	inorganic anion exchanger activity(GO:0005452)
0.0	0.1	GO:0030306	ADP-ribosylation factor binding(GO:0030306)
0.0	0.0	GO:0047631	ADP-ribose diphosphatase activity(GO:0047631)
0.0	0.1	GO:0008020	G-protein coupled photoreceptor activity(GO:0008020)
0.0	0.2	GO:0004115	3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0	0.0	GO:0031544	procollagen-proline 3-dioxygenase activity(GO:0019797) peptidyl-proline 3-dioxygenase activity(GO:0031544)
0.0	0.1	GO:0008467	[heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.0	0.2	GO:0017017	MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.0	0.0	GO:0098518	polynucleotide phosphatase activity(GO:0098518)
0.0	0.1	GO:0008440	inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440) inositol trisphosphate kinase activity(GO:0051766)
0.0	0.2	GO:0035064	methylated histone binding(GO:0035064)
0.0	0.0	GO:0004563	beta-N-acetylhexosaminidase activity(GO:0004563)
0.0	0.0	GO:0019213	deacetylase activity(GO:0019213)
0.0	0.0	GO:0046974	histone methyltransferase activity (H3-K9 specific)(GO:0046974)
0.0	0.0	GO:0034187	obsolete apolipoprotein E binding(GO:0034187)
0.0	0.1	GO:0015385	sodium:proton antiporter activity(GO:0015385)
0.0	0.1	GO:0015643	toxic substance binding(GO:0015643)
0.0	0.2	GO:0051117	ATPase binding(GO:0051117)
0.0	0.0	GO:0004566	beta-glucuronidase activity(GO:0004566)
0.0	0.0	GO:0070643	vitamin D3 25-hydroxylase activity(GO:0030343) vitamin D 25-hydroxylase activity(GO:0070643)
0.0	0.1	GO:0003756	protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864)
0.0	0.0	GO:0016895	exodeoxyribonuclease activity(GO:0004529) exodeoxyribonuclease activity, producing 5'-phosphomonoesters(GO:0016895)
0.0	0.2	GO:0048487	beta-tubulin binding(GO:0048487)
0.0	0.1	GO:0042162	telomeric DNA binding(GO:0042162)
0.0	0.1	GO:0008641	small protein activating enzyme activity(GO:0008641)
0.0	0.1	GO:0004957	prostaglandin E receptor activity(GO:0004957)
0.0	0.1	GO:0019789	SUMO transferase activity(GO:0019789)
0.0	0.1	GO:0017091	AU-rich element binding(GO:0017091)
0.0	0.0	GO:0008061	chitin binding(GO:0008061)
0.0	0.1	GO:0009881	photoreceptor activity(GO:0009881)
0.0	0.0	GO:0031432	titin binding(GO:0031432)
0.0	0.4	GO:0004715	non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.0	0.0	GO:0004849	uridine kinase activity(GO:0004849)
0.0	0.4	GO:0101005	thiol-dependent ubiquitin-specific protease activity(GO:0004843) thiol-dependent ubiquitinyl hydrolase activity(GO:0036459) ubiquitinyl hydrolase activity(GO:0101005)
0.0	0.2	GO:0016289	CoA hydrolase activity(GO:0016289)
0.0	0.3	GO:0008138	protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.0	0.1	GO:0004112	cyclic-nucleotide phosphodiesterase activity(GO:0004112)
0.0	0.0	GO:0030368	interleukin-17 receptor activity(GO:0030368)
0.0	0.0	GO:0016833	oxo-acid-lyase activity(GO:0016833)
0.0	0.0	GO:0050811	GABA receptor binding(GO:0050811)
0.0	0.9	GO:0016881	acid-amino acid ligase activity(GO:0016881)
0.0	0.3	GO:0000049	tRNA binding(GO:0000049)
0.0	0.0	GO:0070097	delta-catenin binding(GO:0070097)
0.0	0.1	GO:0008408	3'-5' exonuclease activity(GO:0008408)
0.0	0.0	GO:0000405	bubble DNA binding(GO:0000405)
0.0	0.1	GO:0000062	fatty-acyl-CoA binding(GO:0000062)
0.0	0.0	GO:0005229	intracellular calcium activated chloride channel activity(GO:0005229)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	1.1	SA PTEN PATHWAY	PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.1	0.2	PID INTEGRIN3 PATHWAY	Beta3 integrin cell surface interactions
0.1	1.9	PID REELIN PATHWAY	Reelin signaling pathway
0.1	1.0	PID TCR JNK PATHWAY	JNK signaling in the CD4+ TCR pathway
0.1	2.6	PID TCR PATHWAY	TCR signaling in naïve CD4+ T cells
0.1	0.5	PID RANBP2 PATHWAY	Sumoylation by RanBP2 regulates transcriptional repression
0.0	0.7	PID NFKAPPAB CANONICAL PATHWAY	Canonical NF-kappaB pathway
0.0	1.1	PID MYC PATHWAY	C-MYC pathway
0.0	0.4	SA FAS SIGNALING	The TNF-type receptor Fas induces apoptosis on ligand binding.
0.0	0.7	PID CD40 PATHWAY	CD40/CD40L signaling
0.0	0.4	ST INTERFERON GAMMA PATHWAY	Interferon gamma pathway.
0.0	2.0	PID P53 REGULATION PATHWAY	p53 pathway
0.0	0.0	PID ER NONGENOMIC PATHWAY	Plasma membrane estrogen receptor signaling
0.0	1.0	PID CDC42 REG PATHWAY	Regulation of CDC42 activity
0.0	1.1	PID NFAT 3PATHWAY	Role of Calcineurin-dependent NFAT signaling in lymphocytes
0.0	0.3	PID INTEGRIN4 PATHWAY	Alpha6 beta4 integrin-ligand interactions
0.0	0.4	PID LPA4 PATHWAY	LPA4-mediated signaling events
0.0	0.0	PID LYMPH ANGIOGENESIS PATHWAY	VEGFR3 signaling in lymphatic endothelium
0.0	0.3	PID SMAD2 3PATHWAY	Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0	0.2	PID WNT CANONICAL PATHWAY	Canonical Wnt signaling pathway
0.0	0.3	PID BETA CATENIN DEG PATHWAY	Degradation of beta catenin
0.0	0.5	PID WNT NONCANONICAL PATHWAY	Noncanonical Wnt signaling pathway
0.0	0.2	ST TUMOR NECROSIS FACTOR PATHWAY	Tumor Necrosis Factor Pathway.
0.0	0.5	PID PI3KCI AKT PATHWAY	Class I PI3K signaling events mediated by Akt
0.0	0.2	PID P38 GAMMA DELTA PATHWAY	Signaling mediated by p38-gamma and p38-delta
0.0	0.1	PID CD8 TCR PATHWAY	TCR signaling in naïve CD8+ T cells
0.0	0.8	PID LKB1 PATHWAY	LKB1 signaling events
0.0	0.1	PID GMCSF PATHWAY	GMCSF-mediated signaling events
0.0	0.3	SA MMP CYTOKINE CONNECTION	Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0	0.3	PID ARF6 DOWNSTREAM PATHWAY	Arf6 downstream pathway
0.0	0.2	PID PDGFRA PATHWAY	PDGFR-alpha signaling pathway
0.0	0.0	ST INTERLEUKIN 4 PATHWAY	Interleukin 4 (IL-4) Pathway
0.0	0.3	PID IL3 PATHWAY	IL3-mediated signaling events
0.0	0.5	PID BCR 5PATHWAY	BCR signaling pathway
0.0	0.1	PID S1P META PATHWAY	Sphingosine 1-phosphate (S1P) pathway
0.0	0.0	PID INTEGRIN1 PATHWAY	Beta1 integrin cell surface interactions
0.0	0.4	PID IL27 PATHWAY	IL27-mediated signaling events
0.0	0.2	PID BARD1 PATHWAY	BARD1 signaling events
0.0	0.3	PID DNA PK PATHWAY	DNA-PK pathway in nonhomologous end joining
0.0	0.3	SIG CD40PATHWAYMAP	Genes related to CD40 signaling
0.0	0.1	PID IL2 STAT5 PATHWAY	IL2 signaling events mediated by STAT5
0.0	0.7	PID AR TF PATHWAY	Regulation of Androgen receptor activity
0.0	0.2	PID NEPHRIN NEPH1 PATHWAY	Nephrin/Neph1 signaling in the kidney podocyte
0.0	0.3	PID THROMBIN PAR4 PATHWAY	PAR4-mediated thrombin signaling events
0.0	0.3	PID HIF1A PATHWAY	Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.0	0.4	PID CERAMIDE PATHWAY	Ceramide signaling pathway
0.0	0.1	PID PI3KCI PATHWAY	Class I PI3K signaling events
0.0	0.2	PID TNF PATHWAY	TNF receptor signaling pathway
0.0	0.2	PID IFNG PATHWAY	IFN-gamma pathway
0.0	0.3	PID IL2 1PATHWAY	IL2-mediated signaling events
0.0	0.2	PID P38 ALPHA BETA PATHWAY	Regulation of p38-alpha and p38-beta
0.0	0.2	PID PRL SIGNALING EVENTS PATHWAY	Signaling events mediated by PRL
0.0	0.2	ST T CELL SIGNAL TRANSDUCTION	T Cell Signal Transduction
0.0	0.0	PID TCR RAS PATHWAY	Ras signaling in the CD4+ TCR pathway
0.0	0.2	PID LIS1 PATHWAY	Lissencephaly gene (LIS1) in neuronal migration and development
0.0	0.1	PID FOXO PATHWAY	FoxO family signaling
0.0	0.2	PID THROMBIN PAR1 PATHWAY	PAR1-mediated thrombin signaling events
0.0	0.3	PID TOLL ENDOGENOUS PATHWAY	Endogenous TLR signaling
0.0	0.2	PID S1P S1P3 PATHWAY	S1P3 pathway
0.0	0.1	PID ERB GENOMIC PATHWAY	Validated nuclear estrogen receptor beta network
0.0	0.1	PID SYNDECAN 3 PATHWAY	Syndecan-3-mediated signaling events
0.0	0.5	PID HNF3B PATHWAY	FOXA2 and FOXA3 transcription factor networks
0.0	0.1	PID IL12 STAT4 PATHWAY	IL12 signaling mediated by STAT4
0.0	0.4	PID CASPASE PATHWAY	Caspase cascade in apoptosis
0.0	0.3	PID ERBB1 INTERNALIZATION PATHWAY	Internalization of ErbB1
0.0	0.1	ST DIFFERENTIATION PATHWAY IN PC12 CELLS	Differentiation Pathway in PC12 Cells; this is a specific case of PAC1 Receptor Pathway.
0.0	0.5	PID PLK1 PATHWAY	PLK1 signaling events
0.0	0.0	PID AJDISS 2PATHWAY	Posttranslational regulation of adherens junction stability and dissassembly
0.0	0.1	PID EPHB FWD PATHWAY	EPHB forward signaling
0.0	0.0	PID TRAIL PATHWAY	TRAIL signaling pathway
0.0	0.0	PID ERBB4 PATHWAY	ErbB4 signaling events
0.0	0.2	SIG INSULIN RECEPTOR PATHWAY IN CARDIAC MYOCYTES	Genes related to the insulin receptor pathway
0.0	0.0	SA B CELL RECEPTOR COMPLEXES	Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.0	0.3	PID MYC REPRESS PATHWAY	Validated targets of C-MYC transcriptional repression

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.7	REACTOME CD28 DEPENDENT VAV1 PATHWAY	Genes involved in CD28 dependent Vav1 pathway
0.1	3.8	REACTOME TCR SIGNALING	Genes involved in TCR signaling
0.1	0.2	REACTOME REGULATION OF SIGNALING BY CBL	Genes involved in Regulation of signaling by CBL
0.1	0.5	REACTOME IL 6 SIGNALING	Genes involved in Interleukin-6 signaling
0.0	0.6	REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE	Genes involved in Synthesis of PIPs at the early endosome membrane
0.0	0.1	REACTOME INTEGRIN ALPHAIIB BETA3 SIGNALING	Genes involved in Integrin alphaIIb beta3 signaling
0.0	0.9	REACTOME NOD1 2 SIGNALING PATHWAY	Genes involved in NOD1/2 Signaling Pathway
0.0	0.9	REACTOME G0 AND EARLY G1	Genes involved in G0 and Early G1
0.0	0.3	REACTOME REGULATION OF IFNG SIGNALING	Genes involved in Regulation of IFNG signaling
0.0	0.1	REACTOME BINDING AND ENTRY OF HIV VIRION	Genes involved in Binding and entry of HIV virion
0.0	0.3	REACTOME CTLA4 INHIBITORY SIGNALING	Genes involved in CTLA4 inhibitory signaling
0.0	0.6	REACTOME CTNNB1 PHOSPHORYLATION CASCADE	Genes involved in Beta-catenin phosphorylation cascade
0.0	0.6	REACTOME RAP1 SIGNALLING	Genes involved in Rap1 signalling
0.0	0.6	REACTOME COSTIMULATION BY THE CD28 FAMILY	Genes involved in Costimulation by the CD28 family
0.0	0.3	REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE	Genes involved in Glutamate Neurotransmitter Release Cycle
0.0	0.4	REACTOME HIGHLY CALCIUM PERMEABLE POSTSYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS	Genes involved in Highly calcium permeable postsynaptic nicotinic acetylcholine receptors
0.0	0.2	REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY	Genes involved in Regulation of the Fanconi anemia pathway
0.0	0.2	REACTOME INTEGRATION OF PROVIRUS	Genes involved in Integration of provirus
0.0	0.6	REACTOME EFFECTS OF PIP2 HYDROLYSIS	Genes involved in Effects of PIP2 hydrolysis
0.0	0.3	REACTOME UNWINDING OF DNA	Genes involved in Unwinding of DNA
0.0	0.5	REACTOME N GLYCAN ANTENNAE ELONGATION IN THE MEDIAL TRANS GOLGI	Genes involved in N-glycan antennae elongation in the medial/trans-Golgi
0.0	0.6	REACTOME CITRIC ACID CYCLE TCA CYCLE	Genes involved in Citric acid cycle (TCA cycle)
0.0	0.3	REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS	Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.0	0.2	REACTOME ACTIVATION OF RAC	Genes involved in Activation of Rac
0.0	0.5	REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS	Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.0	0.2	REACTOME INHIBITION OF REPLICATION INITIATION OF DAMAGED DNA BY RB1 E2F1	Genes involved in Inhibition of replication initiation of damaged DNA by RB1/E2F1
0.0	0.3	REACTOME ABACAVIR TRANSPORT AND METABOLISM	Genes involved in Abacavir transport and metabolism
0.0	0.1	REACTOME TRAF6 MEDIATED IRF7 ACTIVATION	Genes involved in TRAF6 mediated IRF7 activation
0.0	0.5	REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING	Genes involved in Downregulation of TGF-beta receptor signaling
0.0	0.4	REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM	Genes involved in Branched-chain amino acid catabolism
0.0	0.3	REACTOME PROCESSING OF INTRONLESS PRE MRNAS	Genes involved in Processing of Intronless Pre-mRNAs
0.0	0.0	REACTOME PROSTACYCLIN SIGNALLING THROUGH PROSTACYCLIN RECEPTOR	Genes involved in Prostacyclin signalling through prostacyclin receptor
0.0	0.4	REACTOME DEADENYLATION OF MRNA	Genes involved in Deadenylation of mRNA
0.0	0.4	REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS	Genes involved in ABCA transporters in lipid homeostasis
0.0	0.4	REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION	Genes involved in GABA synthesis, release, reuptake and degradation
0.0	0.3	REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS	Genes involved in Glycogen breakdown (glycogenolysis)
0.0	0.4	REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS	Genes involved in Regulation of gene expression in beta cells
0.0	0.5	REACTOME REGULATION OF HYPOXIA INDUCIBLE FACTOR HIF BY OXYGEN	Genes involved in Regulation of Hypoxia-inducible Factor (HIF) by Oxygen
0.0	0.4	REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE	Genes involved in Synthesis of PIPs at the plasma membrane
0.0	0.3	REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE	Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.0	0.1	REACTOME TRAF6 MEDIATED INDUCTION OF TAK1 COMPLEX	Genes involved in TRAF6 mediated induction of TAK1 complex
0.0	0.3	REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS	Genes involved in Trafficking of GluR2-containing AMPA receptors
0.0	0.3	REACTOME CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE	Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
0.0	0.4	REACTOME SULFUR AMINO ACID METABOLISM	Genes involved in Sulfur amino acid metabolism
0.0	0.1	REACTOME REGULATION OF IFNA SIGNALING	Genes involved in Regulation of IFNA signaling
0.0	0.6	REACTOME INTERACTIONS OF VPR WITH HOST CELLULAR PROTEINS	Genes involved in Interactions of Vpr with host cellular proteins
0.0	0.3	REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING	Genes involved in Formation of ATP by chemiosmotic coupling
0.0	0.0	REACTOME GROWTH HORMONE RECEPTOR SIGNALING	Genes involved in Growth hormone receptor signaling
0.0	0.0	REACTOME G BETA GAMMA SIGNALLING THROUGH PI3KGAMMA	Genes involved in G beta:gamma signalling through PI3Kgamma
0.0	0.4	REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA	Genes involved in Circadian Repression of Expression by REV-ERBA
0.0	0.1	REACTOME INHIBITION OF THE PROTEOLYTIC ACTIVITY OF APC C REQUIRED FOR THE ONSET OF ANAPHASE BY MITOTIC SPINDLE CHECKPOINT COMPONENTS	Genes involved in Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components
0.0	0.2	REACTOME ENDOSOMAL VACUOLAR PATHWAY	Genes involved in Endosomal/Vacuolar pathway
0.0	0.1	REACTOME TIE2 SIGNALING	Genes involved in Tie2 Signaling
0.0	0.1	REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING	Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
0.0	0.2	REACTOME TRAFFICKING OF AMPA RECEPTORS	Genes involved in Trafficking of AMPA receptors
0.0	0.2	REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS	Genes involved in Bile salt and organic anion SLC transporters
0.0	0.2	REACTOME RAS ACTIVATION UOPN CA2 INFUX THROUGH NMDA RECEPTOR	Genes involved in Ras activation uopn Ca2+ infux through NMDA receptor
0.0	0.3	REACTOME PYRUVATE METABOLISM AND CITRIC ACID TCA CYCLE	Genes involved in Pyruvate metabolism and Citric Acid (TCA) cycle
0.0	0.2	REACTOME HYALURONAN UPTAKE AND DEGRADATION	Genes involved in Hyaluronan uptake and degradation
0.0	0.4	REACTOME IL 2 SIGNALING	Genes involved in Interleukin-2 signaling
0.0	0.6	REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS	Genes involved in Apoptotic cleavage of cellular proteins
0.0	0.2	REACTOME REGULATORY RNA PATHWAYS	Genes involved in Regulatory RNA pathways
0.0	0.3	REACTOME CGMP EFFECTS	Genes involved in cGMP effects
0.0	0.3	REACTOME METABOLISM OF POLYAMINES	Genes involved in Metabolism of polyamines
0.0	0.2	REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT	Genes involved in Chylomicron-mediated lipid transport
0.0	0.1	REACTOME ACTIVATION OF IRF3 IRF7 MEDIATED BY TBK1 IKK EPSILON	Genes involved in Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon
0.0	0.2	REACTOME ALPHA LINOLENIC ACID ALA METABOLISM	Genes involved in alpha-linolenic acid (ALA) metabolism
0.0	0.8	REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL	Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0	0.0	REACTOME INFLUENZA VIRAL RNA TRANSCRIPTION AND REPLICATION	Genes involved in Influenza Viral RNA Transcription and Replication
0.0	0.2	REACTOME ELONGATION ARREST AND RECOVERY	Genes involved in Elongation arrest and recovery
0.0	0.2	REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY	Genes involved in Adenylate cyclase activating pathway
0.0	2.5	REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION	Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.0	0.1	REACTOME P53 DEPENDENT G1 DNA DAMAGE RESPONSE	Genes involved in p53-Dependent G1 DNA Damage Response
0.0	0.0	REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING	Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.0	0.3	REACTOME KERATAN SULFATE BIOSYNTHESIS	Genes involved in Keratan sulfate biosynthesis
0.0	0.1	REACTOME G PROTEIN ACTIVATION	Genes involved in G-protein activation
0.0	0.0	REACTOME LYSOSOME VESICLE BIOGENESIS	Genes involved in Lysosome Vesicle Biogenesis
0.0	0.4	REACTOME INTERFERON GAMMA SIGNALING	Genes involved in Interferon gamma signaling
0.0	0.0	REACTOME SIGNALING BY NOTCH3	Genes involved in Signaling by NOTCH3
0.0	0.2	REACTOME RECYCLING PATHWAY OF L1	Genes involved in Recycling pathway of L1
0.0	0.9	REACTOME MITOTIC PROMETAPHASE	Genes involved in Mitotic Prometaphase
0.0	0.1	REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS	Genes involved in Membrane binding and targetting of GAG proteins
0.0	0.7	REACTOME METABOLISM OF VITAMINS AND COFACTORS	Genes involved in Metabolism of vitamins and cofactors
0.0	0.0	REACTOME GPVI MEDIATED ACTIVATION CASCADE	Genes involved in GPVI-mediated activation cascade
0.0	0.1	REACTOME ACTIVATION OF BH3 ONLY PROTEINS	Genes involved in Activation of BH3-only proteins
0.0	0.0	REACTOME VIF MEDIATED DEGRADATION OF APOBEC3G	Genes involved in Vif-mediated degradation of APOBEC3G
0.0	0.0	REACTOME SCF BETA TRCP MEDIATED DEGRADATION OF EMI1	Genes involved in SCF-beta-TrCP mediated degradation of Emi1
0.0	0.1	REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION	Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.0	0.1	REACTOME BASE FREE SUGAR PHOSPHATE REMOVAL VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY	Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway
0.0	0.2	REACTOME FANCONI ANEMIA PATHWAY	Genes involved in Fanconi Anemia pathway
0.0	0.1	REACTOME INTRINSIC PATHWAY FOR APOPTOSIS	Genes involved in Intrinsic Pathway for Apoptosis
0.0	0.8	REACTOME MEIOTIC SYNAPSIS	Genes involved in Meiotic Synapsis
0.0	0.1	REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE	Genes involved in Synthesis of PIPs at the Golgi membrane
0.0	0.1	REACTOME ACTIVATION OF NMDA RECEPTOR UPON GLUTAMATE BINDING AND POSTSYNAPTIC EVENTS	Genes involved in Activation of NMDA receptor upon glutamate binding and postsynaptic events
0.0	0.0	REACTOME RIP MEDIATED NFKB ACTIVATION VIA DAI	Genes involved in RIP-mediated NFkB activation via DAI
0.0	0.3	REACTOME THROMBIN SIGNALLING THROUGH PROTEINASE ACTIVATED RECEPTORS PARS	Genes involved in Thrombin signalling through proteinase activated receptors (PARs)
0.0	0.4	REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS	Genes involved in Golgi Associated Vesicle Biogenesis
0.0	0.7	REACTOME TCA CYCLE AND RESPIRATORY ELECTRON TRANSPORT	Genes involved in The citric acid (TCA) cycle and respiratory electron transport
0.0	0.2	REACTOME CHONDROITIN SULFATE BIOSYNTHESIS	Genes involved in Chondroitin sulfate biosynthesis
0.0	0.1	REACTOME SIGNAL TRANSDUCTION BY L1	Genes involved in Signal transduction by L1
0.0	0.1	REACTOME P38MAPK EVENTS	Genes involved in p38MAPK events
0.0	1.1	REACTOME 3 UTR MEDIATED TRANSLATIONAL REGULATION	Genes involved in 3' -UTR-mediated translational regulation
0.0	0.1	REACTOME THE ROLE OF NEF IN HIV1 REPLICATION AND DISEASE PATHOGENESIS	Genes involved in The role of Nef in HIV-1 replication and disease pathogenesis
0.0	0.1	REACTOME ASSOCIATION OF LICENSING FACTORS WITH THE PRE REPLICATIVE COMPLEX	Genes involved in Association of licensing factors with the pre-replicative complex

Results for NKX6-2

Z-value: 2.14

Motif logo

Transcription factors associated with NKX6-2

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

Activity of the NKX6-2 motif across conditions

Conditions sorted by the z-value of the NKX6-2 motif activity

Top target CREs of the motif:

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of NKX6-2

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category:

Gene overrepresentation in curated gene sets: canonical pathways category:

Gene overrepresentation in curated gene sets: REACTOME pathways category: