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ENCODE: H3K4me1 ChIP-Seq of primary human cells
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Results for NOTO_VSX2_DLX2_DLX6_NKX6-1

Z-value: 0.36

Motif logo

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Transcription factors associated with NOTO_VSX2_DLX2_DLX6_NKX6-1

Gene Symbol Gene ID Gene Info
NOTO
ENSG00000214513.3 notochord homeobox
VSX2
ENSG00000119614.2 visual system homeobox 2
DLX2
ENSG00000115844.6 distal-less homeobox 2
DLX6
ENSG00000006377.9 distal-less homeobox 6
NKX6-1
ENSG00000163623.5 NK6 homeobox 1

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE Gene Distance Association probability Pearson corr. coef. P-value Plot
chr2_172963100_172963251DLX244530.235017-0.818.6e-03Click!
chr2_172963272_172963426DLX242790.237927-0.818.6e-03Click!
chr2_172962678_172962829DLX248750.229059-0.781.4e-02Click!
chr2_172970558_172970785DLX230430.274625-0.732.7e-02Click!
chr2_172983664_172983815DLX2161110.193934-0.703.6e-02Click!
chr7_96634629_96634816DLX61380.916168-0.761.6e-02Click!
chr7_96634448_96634599DLX63370.746776-0.432.5e-01Click!
chr7_96635544_96635719DLX63410.788171-0.314.2e-01Click!
chr7_96635897_96636514DLX65320.5517530.215.9e-01Click!
chr7_96635193_96635344DLX6220.957836-0.117.8e-01Click!
chr4_85414076_85414325NKX6-139030.3441540.881.5e-03Click!
chr4_85414774_85414925NKX6-132540.365933-0.732.7e-02Click!
chr4_85414514_85414716NKX6-134880.356869-0.693.9e-02Click!
chr4_85414978_85415129NKX6-130500.375302-0.646.3e-02Click!
chr4_85418461_85418631NKX6-14430.896615-0.571.1e-01Click!
chr2_73404020_73404496NOTO251280.131991-0.637.1e-02Click!
chr2_73428847_73428998NOTO4640.764129-0.618.4e-02Click!
chr2_73402978_73403574NOTO261100.130543-0.452.2e-01Click!
chr2_73403809_73403998NOTO254830.131472-0.432.5e-01Click!
chr2_73402351_73402559NOTO269310.129301-0.412.7e-01Click!
chr14_74707717_74707868VSX216170.345319-0.627.6e-02Click!
chr14_74709486_74709637VSX233860.2116470.609.0e-02Click!
chr14_74707166_74707367VSX210910.4791660.551.2e-01Click!
chr14_74684580_74684796VSX2214870.151649-0.501.7e-01Click!
chr14_74724538_74725207VSX2186970.135256-0.472.1e-01Click!

Activity of the NOTO_VSX2_DLX2_DLX6_NKX6-1 motif across conditions

Conditions sorted by the z-value of the NOTO_VSX2_DLX2_DLX6_NKX6-1 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE) Target Score Top associated gene Gene Info Distance of CRE to TSS CRE/Gene association probability
chr14_75982573_75982735 0.11 BATF
 basic leucine zipper transcription factor, ATF-like
 6114
 0.21
chrX_11784442_11784722 0.10 MSL3
 male-specific lethal 3 homolog (Drosophila)
 6835
 0.32
chrX_154356045_154356312 0.09 MTCP1
 mature T-cell proliferation 1
 19872
 0.16
chr16_73092870_73093114 0.09 ZFHX3
 zinc finger homeobox 3
 605
 0.79
chr13_46893880_46894070 0.09 ENSG00000223336
 .
 54750
 0.1
chr13_32616590_32616779 0.09 FRY-AS1
 FRY antisense RNA 1
 10908
 0.22
chr2_114633518_114633816 0.08 ACTR3
 ARP3 actin-related protein 3 homolog (yeast)
 13870
 0.21
chr10_4170376_4170710 0.08 KLF6
 Kruppel-like factor 6
 343070
 0.01
chr3_107697281_107697722 0.08 CD47
 CD47 molecule
 79707
 0.11
chr19_47948776_47948927 0.08 MEIS3
 Meis homeobox 3
 26071
 0.11
chr17_38376031_38376425 0.08 WIPF2
 WAS/WASL interacting protein family, member 2
 124
 0.95
chr2_204726088_204726239 0.08 CTLA4
 cytotoxic T-lymphocyte-associated protein 4
 6346
 0.27
chr5_156695529_156695722 0.07 CYFIP2
 cytoplasmic FMR1 interacting protein 2
 737
 0.55
chr2_30557961_30558163 0.07 ENSG00000221377
 .
 97252
 0.07
chr7_6298731_6299016 0.07 CYTH3
 cytohesin 3
 13402
 0.18
chr3_71862606_71862965 0.07 ENSG00000239250
 .
 13543
 0.2
chr14_60761646_60761856 0.07 PPM1A
 protein phosphatase, Mg2+/Mn2+ dependent, 1A
 38271
 0.17
chr7_106512561_106512750 0.07 PIK3CG
 phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma
 6731
 0.28
chr8_19331197_19331348 0.07 CSGALNACT1
 chondroitin sulfate N-acetylgalactosaminyltransferase 1
 128104
 0.06
chr10_73513150_73513301 0.07 C10orf54
 chromosome 10 open reading frame 54
 4162
 0.23
chr2_204587544_204587695 0.07 CD28
 CD28 molecule
 16203
 0.22
chr19_55008845_55009031 0.07 LAIR2
 leukocyte-associated immunoglobulin-like receptor 2
 162
 0.91
chr1_172666866_172667065 0.07 FASLG
 Fas ligand (TNF superfamily, member 6)
 38807
 0.19
chr11_20179253_20179404 0.07 DBX1
 developing brain homeobox 1
 2542
 0.34
chrX_118818778_118818993 0.07 SEPT6
 septin 6
 7907
 0.18
chr13_111837384_111838319 0.07 ARHGEF7
 Rho guanine nucleotide exchange factor (GEF) 7
 566
 0.79
chr1_208047000_208047151 0.07 CD34
 CD34 molecule
 16762
 0.25
chr22_36802881_36803061 0.07 MYH9
 myosin, heavy chain 9, non-muscle
 18908
 0.15
chr2_136815081_136815280 0.06 AC093391.2
45145
 0.15
chr4_78721201_78721381 0.06 CNOT6L
 CCR4-NOT transcription complex, subunit 6-like
 18926
 0.25
chr4_68440895_68441046 0.06 STAP1
 signal transducing adaptor family member 1
 16524
 0.2
chrX_41117068_41117219 0.06 RP5-1172N10.4
24257
 0.17
chr6_112069279_112069430 0.06 FYN
 FYN oncogene related to SRC, FGR, YES
 10963
 0.26
chr2_8631121_8631315 0.06 AC011747.7
184678
 0.03
chr13_49484698_49484849 0.06 ENSG00000265585
 .
 19575
 0.22
chr4_153738270_153738485 0.06 ARFIP1
 ADP-ribosylation factor interacting protein 1
 37240
 0.16
chr2_8615200_8615353 0.06 AC011747.7
200620
 0.03
chr7_50461192_50461505 0.06 ENSG00000200815
 .
 41730
 0.16
chr8_82065263_82065697 0.06 PAG1
 phosphoprotein associated with glycosphingolipid microdomains 1
 41177
 0.19
chr20_57961202_57961353 0.06 ENSG00000263903
 .
 39742
 0.19
chr12_104916695_104916846 0.06 CHST11
 carbohydrate (chondroitin 4) sulfotransferase 11
 65856
 0.12
chr12_27107136_27107312 0.06 FGFR1OP2
 FGFR1 oncogene partner 2
 15791
 0.13
chr11_114065637_114066010 0.06 NNMT
 nicotinamide N-methyltransferase
 62730
 0.12
chr1_206753706_206754386 0.06 RASSF5
 Ras association (RalGDS/AF-6) domain family member 5
 23553
 0.13
chr3_16883717_16883868 0.06 PLCL2
 phospholipase C-like 2
 42660
 0.19
chr15_76578114_76578265 0.06 ETFA
 electron-transfer-flavoprotein, alpha polypeptide
 6643
 0.24
chr5_96345721_96346249 0.06 ENSG00000200884
 .
 47524
 0.12
chr11_128603513_128603832 0.06 FLI1
 Fli-1 proto-oncogene, ETS transcription factor
 31013
 0.16
chr2_143889620_143889771 0.06 ARHGAP15
 Rho GTPase activating protein 15
 2812
 0.35
chr1_192536616_192536790 0.06 RP5-1011O1.2
356
 0.89
chr2_30489326_30489587 0.06 LBH
 limb bud and heart development
 34410
 0.19
chr1_108327675_108328746 0.06 ENSG00000265536
 .
 9332
 0.26
chr3_151932265_151932416 0.06 MBNL1
 muscleblind-like splicing regulator 1
 53489
 0.14
chr19_24222899_24223050 0.06 ZNF254
 zinc finger protein 254
 6698
 0.24
chr17_72489409_72489599 0.06 CD300A
 CD300a molecule
 26503
 0.12
chr16_384366_384517 0.06 AXIN1
 axin 1
 18008
 0.1
chr10_44277312_44277574 0.06 ZNF32
 zinc finger protein 32
 133139
 0.05
chr3_18470958_18471238 0.06 SATB1
 SATB homeobox 1
 4237
 0.24
chr9_33976084_33976235 0.06 UBAP2
 ubiquitin associated protein 2
 12882
 0.13
chr14_90187580_90187731 0.06 ENSG00000200312
 .
 8800
 0.23
chr16_74620197_74620348 0.06 GLG1
 golgi glycoprotein 1
 20720
 0.2
chr2_174756889_174757040 0.06 SP3
 Sp3 transcription factor
 71983
 0.13
chr3_196150607_196150758 0.06 UBXN7-AS1
 UBXN7 antisense RNA 1
 7553
 0.11
chr9_111350242_111350393 0.06 ENSG00000222512
 .
 229108
 0.02
chr3_157824510_157824697 0.06 SHOX2
 short stature homeobox 2
 311
 0.83
chr4_25953219_25953370 0.06 SMIM20
 small integral membrane protein 20
 37363
 0.21
chrX_13023409_13023615 0.06 TMSB4X
 thymosin beta 4, X-linked
 29735
 0.18
chr22_24908185_24908422 0.06 AP000355.2
4173
 0.16
chr2_99302058_99302209 0.06 MGAT4A
 mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme A
 22197
 0.2
chr16_68502814_68502979 0.06 ENSG00000199263
 .
 5671
 0.17
chr2_86332208_86332925 0.06 POLR1A
 polymerase (RNA) I polypeptide A, 194kDa
 712
 0.41
chr1_45100216_45100404 0.05 RNF220
 ring finger protein 220
 2906
 0.21
chr1_65408789_65408940 0.05 JAK1
 Janus kinase 1
 23323
 0.22
chr18_67686310_67686461 0.05 RTTN
 rotatin
 1569
 0.52
chr11_128600475_128600823 0.05 FLI1
 Fli-1 proto-oncogene, ETS transcription factor
 34036
 0.15
chr1_117311065_117311639 0.05 CD2
 CD2 molecule
 14263
 0.21
chr6_35838270_35838421 0.05 SRPK1
 SRSF protein kinase 1
 50479
 0.1
chr14_39893718_39893961 0.05 FBXO33
 F-box protein 33
 7240
 0.26
chrX_15779492_15779655 0.05 CA5B
 carbonic anhydrase VB, mitochondrial
 11480
 0.18
chr7_55627006_55627245 0.05 VOPP1
 vesicular, overexpressed in cancer, prosurvival protein 1
 5545
 0.24
chrX_48533482_48533772 0.05 WAS
 Wiskott-Aldrich syndrome
 1358
 0.32
chr10_82288993_82289258 0.05 RP11-137H2.4
6573
 0.22
chr10_17548800_17549076 0.05 ST8SIA6
 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 6
 52609
 0.13
chr19_9976591_9976870 0.05 OLFM2
 olfactomedin 2
 7886
 0.11
chr2_215664954_215665105 0.05 BARD1
 BRCA1 associated RING domain 1
 9368
 0.21
chr16_304069_304251 0.05 ITFG3
 integrin alpha FG-GAP repeat containing 3
 467
 0.67
chr17_76707598_76707858 0.05 CYTH1
 cytohesin 1
 5379
 0.21
chr22_36843971_36844162 0.05 ENSG00000252225
 .
 7051
 0.15
chr15_40489916_40490242 0.05 PAK6
 p21 protein (Cdc42/Rac)-activated kinase 6
 19550
 0.12
chr13_50706871_50707077 0.05 DLEU1
 deleted in lymphocytic leukemia 1 (non-protein coding)
 50667
 0.13
chr14_65547049_65547200 0.05 RP11-840I19.3
1628
 0.32
chr18_12421274_12421492 0.05 SLMO1
 slowmo homolog 1 (Drosophila)
 98
 0.96
chr11_128173540_128173801 0.05 ETS1
 v-ets avian erythroblastosis virus E26 oncogene homolog 1
 201619
 0.03
chr6_117922468_117923064 0.05 GOPC
 golgi-associated PDZ and coiled-coil motif containing
 761
 0.74
chr2_204583285_204583561 0.05 CD28
 CD28 molecule
 12007
 0.23
chr12_19573889_19574040 0.05 AEBP2
 AE binding protein 2
 16964
 0.22
chr5_95150906_95151226 0.05 GLRX
 glutaredoxin (thioltransferase)
 7349
 0.16
chr4_123133902_123134053 0.05 KIAA1109
 KIAA1109
 6647
 0.31
chr9_37340676_37340827 0.05 ENSG00000206784
 .
 18495
 0.19
chr1_93445938_93446179 0.05 ENSG00000238787
 .
 1807
 0.23
chr5_169731037_169731197 0.05 LCP2
 lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa)
 5886
 0.24
chr16_30188682_30188851 0.05 CORO1A
 coronin, actin binding protein, 1A
 5382
 0.09
chr3_44345343_44345494 0.05 TCAIM
 T cell activation inhibitor, mitochondrial
 34193
 0.16
chr20_10652876_10653323 0.05 RP11-103J8.1
477
 0.79
chr11_121198510_121198941 0.05 SC5D
 sterol-C5-desaturase
 35164
 0.22
chr17_71199413_71199564 0.05 COG1
 component of oligomeric golgi complex 1
 2266
 0.24
chr14_71512203_71512354 0.05 PCNX
 pecanex homolog (Drosophila)
 2399
 0.43
chrX_96290122_96290273 0.05 RPA4
 replication protein A4, 30kDa
 151290
 0.05
chr3_71543419_71543780 0.05 ENSG00000221264
 .
 47641
 0.15
chr15_86235842_86236056 0.05 RP11-815J21.1
8391
 0.12
chr11_48040089_48040240 0.05 AC103828.1
2757
 0.3
chr2_54763445_54763596 0.05 AC092839.3
4314
 0.22
chr16_3863779_3863930 0.05 CREBBP
 CREB binding protein
 32986
 0.17
chr1_25969522_25969744 0.05 RP1-187B23.1
15969
 0.18
chr5_61613165_61613316 0.05 KIF2A
 kinesin heavy chain member 2A
 5600
 0.28
chr10_11224652_11224918 0.05 RP3-323N1.2
11446
 0.22
chr2_68470770_68470921 0.05 PPP3R1
 protein phosphatase 3, regulatory subunit B, alpha
 7435
 0.14
chr17_29146107_29146385 0.05 CRLF3
 cytokine receptor-like factor 3
 5443
 0.13
chrX_24207530_24207774 0.05 ZFX
 zinc finger protein, X-linked
 16820
 0.19
chr6_13686993_13687323 0.05 RANBP9
 RAN binding protein 9
 22
 0.98
chr10_4121743_4121894 0.05 KLF6
 Kruppel-like factor 6
 294345
 0.01
chr2_29593489_29593640 0.05 ENSG00000266310
 .
 133295
 0.05
chr7_143007723_143007933 0.05 CLCN1
 chloride channel, voltage-sensitive 1
 5391
 0.1
chr14_73918520_73918671 0.05 NUMB
 numb homolog (Drosophila)
 6394
 0.17
chr13_46745351_46745718 0.05 ENSG00000240767
 .
 1651
 0.31
chrX_38757954_38758105 0.05 MID1IP1-AS1
 MID1IP1 antisense RNA 1
 94893
 0.08
chr14_66052416_66052567 0.05 FUT8
 fucosyltransferase 8 (alpha (1,6) fucosyltransferase)
 83642
 0.1
chr9_132708644_132709361 0.05 RP11-409K20.6
13187
 0.19
chr12_56429367_56429565 0.05 RP11-603J24.4
6124
 0.09
chr11_48078680_48078903 0.05 ENSG00000263693
 .
 39543
 0.14
chr5_156969848_156970007 0.05 AC106801.1
23045
 0.14
chr16_29673426_29673713 0.05 SPN
 sialophorin
 731
 0.45
chr1_185564303_185564454 0.05 ENSG00000207108
 .
 35282
 0.18
chr10_63813717_63813907 0.05 ARID5B
 AT rich interactive domain 5B (MRF1-like)
 4842
 0.3
chr1_206817821_206817972 0.05 DYRK3
 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3
 8722
 0.14
chr5_126093902_126094474 0.05 ENSG00000252185
 .
 3079
 0.3
chr2_63280572_63281076 0.05 OTX1
 orthodenticle homeobox 1
 2887
 0.3
chr8_19552777_19552928 0.05 CSGALNACT1
 chondroitin sulfate N-acetylgalactosaminyltransferase 1
 12580
 0.3
chr14_96978213_96978375 0.05 PAPOLA
 poly(A) polymerase alpha
 9106
 0.18
chr19_8628819_8628970 0.05 MYO1F
 myosin IF
 13428
 0.11
chr5_156711613_156711855 0.05 CYFIP2
 cytoplasmic FMR1 interacting protein 2
 638
 0.67
chr7_37011204_37011355 0.05 ELMO1
 engulfment and cell motility 1
 13386
 0.2
chr4_86636333_86636484 0.05 ENSG00000266421
 .
 7213
 0.29
chr9_123882798_123883340 0.05 CNTRL
 centriolin
 1010
 0.59
chr8_42607900_42608051 0.05 CHRNA6
 cholinergic receptor, nicotinic, alpha 6 (neuronal)
 15778
 0.17
chr2_214096607_214096758 0.05 SPAG16
 sperm associated antigen 16
 52431
 0.17
chr5_92921754_92921905 0.05 ENSG00000237187
 .
 475
 0.81
chr17_34906652_34907000 0.05 GGNBP2
 gametogenetin binding protein 2
 5473
 0.14
chr7_140171728_140171879 0.05 MKRN1
 makorin ring finger protein 1
 6500
 0.2
chr6_88403463_88403724 0.05 AKIRIN2
 akirin 2
 8334
 0.2
chr5_110428605_110428905 0.05 WDR36
 WD repeat domain 36
 736
 0.49
chr11_117863729_117863895 0.05 IL10RA
 interleukin 10 receptor, alpha
 6703
 0.2
chr19_13951569_13952139 0.05 ENSG00000207980
 .
 4381
 0.09
chr7_105088467_105088805 0.05 SRPK2
 SRSF protein kinase 2
 58798
 0.11
chr1_174929832_174929983 0.05 RABGAP1L
 RAB GTPase activating protein 1-like
 3998
 0.18
chr8_17788613_17788764 0.05 PCM1
 pericentriolar material 1
 6435
 0.21
chr11_57480467_57480618 0.05 TMX2
 thioredoxin-related transmembrane protein 2
 463
 0.58
chr18_2976679_2976953 0.05 LPIN2
 lipin 2
 6055
 0.16
chr11_118935786_118935937 0.05 RP11-110I1.13
2548
 0.1
chr2_43402387_43402951 0.05 ZFP36L2
 ZFP36 ring finger protein-like 2
 51079
 0.14
chr6_159453780_159453931 0.05 RP1-111C20.4
6877
 0.19
chr5_98269675_98269959 0.05 ENSG00000200351
 .
 2634
 0.3
chr15_60850340_60850622 0.05 CTD-2501E16.2
28309
 0.16
chr3_195121741_195121910 0.05 ENSG00000207368
 .
 18450
 0.19
chr9_129252809_129252960 0.05 ENSG00000221768
 .
 40386
 0.14
chr15_63503072_63503368 0.05 RAB8B
 RAB8B, member RAS oncogene family
 21415
 0.19
chr2_64416040_64416191 0.05 AC074289.1
17994
 0.23
chr17_75456251_75456589 0.05 SEPT9
 septin 9
 3972
 0.18
chr6_109381834_109382031 0.05 ENSG00000199944
 .
 1115
 0.52
chr5_100212754_100212905 0.05 ST8SIA4
 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4
 26089
 0.24
chr17_57866912_57867150 0.05 RP11-619I22.1
4857
 0.18
chr2_210850912_210851168 0.05 RPE
 ribulose-5-phosphate-3-epimerase
 16249
 0.17
chr1_100905257_100905795 0.05 RP5-837M10.4
46027
 0.13
chr4_81061096_81061271 0.05 PRDM8
 PR domain containing 8
 44256
 0.15
chr12_94600310_94600885 0.05 RP11-74K11.2
20777
 0.19
chr21_16057852_16058003 0.05 AF165138.7
 Protein LOC388813
 26785
 0.23
chr1_198627688_198627997 0.05 RP11-553K8.5
8348
 0.25
chr3_53380504_53380708 0.05 DCP1A
 decapping mRNA 1A
 946
 0.5
chr11_82885812_82886113 0.05 PCF11
 PCF11 cleavage and polyadenylation factor subunit
 3669
 0.19
chr15_75414732_75414883 0.05 ENSG00000252722
 .
 800
 0.61
chr20_6758219_6758370 0.05 BMP2
 bone morphogenetic protein 2
 9983
 0.3
chr12_25432989_25433140 0.04 KRAS
 Kirsten rat sarcoma viral oncogene homolog
 29194
 0.18
chr13_28726745_28726896 0.04 PAN3
 PAN3 poly(A) specific ribonuclease subunit homolog (S. cerevisiae)
 13650
 0.18
chr14_98641364_98641616 0.04 ENSG00000222066
 .
 156597
 0.04
chr3_88112020_88112171 0.04 RP11-159G9.5
 Uncharacterized protein
 3671
 0.23
chr12_68530648_68530810 0.04 IFNG
 interferon, gamma
 22798
 0.24
chrX_109266234_109266489 0.04 TMEM164
 transmembrane protein 164
 20018
 0.2
chr15_91880318_91880572 0.04 SV2B
 synaptic vesicle glycoprotein 2B
 111345
 0.07
chr13_99892072_99892468 0.04 GPR18
 G protein-coupled receptor 18
 18358
 0.17
chr5_156636522_156636760 0.04 CTB-4E7.1
14749
 0.12
chr10_26740284_26740599 0.04 APBB1IP
 amyloid beta (A4) precursor protein-binding, family B, member 1 interacting protein
 13087
 0.26
chr11_129956983_129957182 0.04 APLP2
 amyloid beta (A4) precursor-like protein 2
 16619
 0.2
chr19_42318679_42318830 0.04 CEACAM3
 carcinoembryonic antigen-related cell adhesion molecule 3
 17669
 0.1
chr7_157674477_157674628 0.04 RP11-452C13.1
13322
 0.23
chr5_169066038_169066189 0.04 DOCK2
 dedicator of cytokinesis 2
 1862
 0.43
chr5_61874985_61875174 0.04 LRRC70
 leucine rich repeat containing 70
 377
 0.53
chr1_235439552_235439703 0.04 GGPS1
 geranylgeranyl diphosphate synthase 1
 51038
 0.11
chr4_78777778_78777929 0.04 MRPL1
 mitochondrial ribosomal protein L1
 5821
 0.28
chr11_87248503_87248654 0.04 ENSG00000223015
 .
 69097
 0.13
chr1_100862907_100863178 0.04 ENSG00000216067
 .
 18711
 0.19

Histogram of CRE-TSS distances for CREs targeted by :

Histogram of

Rank distribution of CRE target scores:

Histogram of target CRE score.

Distribution of target CREs across different genomic regions:

Weighted Piechart of Weighted Piechart of Weighted Piechart of

Network of associatons between targets according to the STRING database.

First level regulatory network of NOTO_VSX2_DLX2_DLX6_NKX6-1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0033152 immunoglobulin V(D)J recombination(GO:0033152)
0.0 0.1 GO:0031580 membrane raft polarization(GO:0001766) membrane raft distribution(GO:0031580)
0.0 0.1 GO:0030854 positive regulation of granulocyte differentiation(GO:0030854)
0.0 0.0 GO:0048742 regulation of skeletal muscle fiber development(GO:0048742)
0.0 0.0 GO:0042996 regulation of Golgi to plasma membrane protein transport(GO:0042996)
0.0 0.0 GO:0072182 nephron tubule epithelial cell differentiation(GO:0072160) regulation of nephron tubule epithelial cell differentiation(GO:0072182) regulation of epithelial cell differentiation involved in kidney development(GO:2000696)
0.0 0.1 GO:0006610 ribosomal protein import into nucleus(GO:0006610)
0.0 0.0 GO:0045722 positive regulation of gluconeogenesis(GO:0045722)
0.0 0.0 GO:0043615 astrocyte cell migration(GO:0043615)
0.0 0.1 GO:0006491 N-glycan processing(GO:0006491)
0.0 0.0 GO:0072216 positive regulation of metanephros development(GO:0072216)
0.0 0.1 GO:0045066 regulatory T cell differentiation(GO:0045066)
0.0 0.0 GO:2000758 positive regulation of histone acetylation(GO:0035066) positive regulation of protein acetylation(GO:1901985) positive regulation of peptidyl-lysine acetylation(GO:2000758)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.0 0.1 GO:0046934 phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) phosphatidylinositol bisphosphate kinase activity(GO:0052813)
0.0 0.0 GO:0042608 T cell receptor binding(GO:0042608)

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.0 REACTOME IRAK1 RECRUITS IKK COMPLEX Genes involved in IRAK1 recruits IKK complex
0.0 0.1 REACTOME CD28 DEPENDENT VAV1 PATHWAY Genes involved in CD28 dependent Vav1 pathway