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ENCODE: H3K4me1 ChIP-Seq of primary human cells
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CREMA is a free online tool that recognizes most important transcription factors that change the chromatin state across different samples.

Results for NR0B1

Z-value: 1.34

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Transcription factors associated with NR0B1

Gene Symbol Gene ID Gene Info
NR0B1
ENSG00000169297.6 NR0B1

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE Gene Distance Association probability Pearson corr. coef. P-value Plot
NR0B1chrX_30327610_30327761300.9770160.304.4e-01Click!

Activity of the NR0B1 motif across conditions

Conditions sorted by the z-value of the NR0B1 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE) Target Score Top associated gene Gene Info Distance of CRE to TSS CRE/Gene association probability
chr10_134387680_134387844 0.35 INPP5A
 inositol polyphosphate-5-phosphatase, 40kDa
 33668
 0.18
chr12_67753116_67753506 0.27 CAND1
 cullin-associated and neddylation-dissociated 1
 60559
 0.16
chrX_102719262_102719533 0.27 LL0XNC01-250H12.3
33054
 0.14
chr9_109623180_109623558 0.23 ZNF462
 zinc finger protein 462
 2009
 0.38
chr21_47603311_47603605 0.23 SPATC1L
 spermatogenesis and centriole associated 1-like
 915
 0.34
chr3_35680980_35681355 0.22 ARPP21
 cAMP-regulated phosphoprotein, 21kDa
 86
 0.98
chr3_123601595_123601750 0.22 MYLK
 myosin light chain kinase
 1477
 0.48
chr1_54147270_54147460 0.22 ENSG00000239007
 .
 7120
 0.23
chr17_3795838_3795989 0.21 CAMKK1
 calcium/calmodulin-dependent protein kinase kinase 1, alpha
 424
 0.81
chr3_193857613_193857764 0.21 HES1
 hes family bHLH transcription factor 1
 3754
 0.23
chr17_62061939_62062090 0.21 SCN4A
 sodium channel, voltage-gated, type IV, alpha subunit
 11736
 0.13
chr7_30265884_30266155 0.20 ZNRF2
 zinc and ring finger 2
 57904
 0.1
chr8_133685594_133685859 0.20 LRRC6
 leucine rich repeat containing 6
 2079
 0.33
chr3_53529546_53529812 0.20 CACNA1D
 calcium channel, voltage-dependent, L type, alpha 1D subunit
 485
 0.83
chr6_15281229_15281559 0.20 JARID2
 jumonji, AT rich interactive domain 2
 32251
 0.14
chr9_125765061_125765504 0.20 RABGAP1
 RAB GTPase activating protein 1
 30506
 0.12
chr5_369667_369964 0.20 AHRR
 aryl-hydrocarbon receptor repressor
 26172
 0.15
chr7_138666516_138666785 0.20 KIAA1549
 KIAA1549
 586
 0.8
chr18_43915409_43915560 0.20 RNF165
 ring finger protein 165
 1297
 0.59
chr3_3841565_3841901 0.20 LRRN1
 leucine rich repeat neuronal 1
 612
 0.85
chr1_85463137_85463288 0.20 MCOLN2
 mucolipin 2
 417
 0.8
chr19_41828944_41829156 0.19 CCDC97
 coiled-coil domain containing 97
 3412
 0.13
chr19_1214948_1215099 0.19 STK11
 serine/threonine kinase 11
 6189
 0.1
chr13_41239473_41239624 0.19 FOXO1
 forkhead box O1
 1186
 0.56
chr12_68043974_68044273 0.19 DYRK2
 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 2
 661
 0.78
chr7_100487586_100487737 0.19 UFSP1
 UFM1-specific peptidase 1 (non-functional)
 322
 0.77
chr12_54780838_54781095 0.19 ZNF385A
 zinc finger protein 385A
 1414
 0.25
chr12_27702595_27702869 0.18 PPFIBP1
 PTPRF interacting protein, binding protein 1 (liprin beta 1)
 11676
 0.23
chr6_133562644_133562795 0.18 EYA4
 eyes absent homolog 4 (Drosophila)
 5
 0.99
chr1_12227573_12227724 0.18 TNFRSF1B
 tumor necrosis factor receptor superfamily, member 1B
 588
 0.71
chr5_56741137_56741395 0.18 ENSG00000264748
 .
 36464
 0.16
chr2_206595324_206595734 0.18 AC007362.3
33148
 0.2
chr17_45401427_45401685 0.18 EFCAB13
 EF-hand calcium binding domain 13
 165
 0.84
chr3_120278487_120278806 0.17 NDUFB4
 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 4, 15kDa
 36510
 0.19
chr19_41083149_41083300 0.17 SHKBP1
 SH3KBP1 binding protein 1
 160
 0.94
chr3_37964439_37964907 0.17 CTDSPL
 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like
 41397
 0.12
chr9_127005358_127005801 0.17 NEK6
 NIMA-related kinase 6
 14306
 0.17
chr11_64322674_64322825 0.17 SLC22A11
 solute carrier family 22 (organic anion/urate transporter), member 11
 349
 0.87
chr3_42306280_42306453 0.17 CCK
 cholecystokinin
 29
 0.98
chr2_42721697_42722094 0.17 MTA3
 metastasis associated 1 family, member 3
 186
 0.85
chr1_156867514_156867913 0.17 PEAR1
 platelet endothelial aggregation receptor 1
 4190
 0.15
chr11_117185411_117185562 0.17 CEP164
 centrosomal protein 164kDa
 213
 0.87
chr12_96588798_96589434 0.17 ELK3
 ELK3, ETS-domain protein (SRF accessory protein 2)
 724
 0.7
chr9_131218778_131219020 0.17 ODF2
 outer dense fiber of sperm tails 2
 154
 0.92
chr3_194117055_194117206 0.17 GP5
 glycoprotein V (platelet)
 1953
 0.3
chr8_1992676_1993045 0.17 MYOM2
 myomesin 2
 295
 0.94
chr16_4723224_4723375 0.17 NUDT16L1
 nudix (nucleoside diphosphate linked moiety X)-type motif 16-like 1
 20396
 0.1
chr17_40673227_40673704 0.17 ENSG00000265611
 .
 7259
 0.08
chr12_11653096_11653254 0.17 RP11-711K1.7
13563
 0.19
chr19_8794292_8794443 0.17 ACTL9
 actin-like 9
 14805
 0.19
chr14_68864676_68864966 0.16 RAD51B
 RAD51 paralog B
 13406
 0.29
chr12_77718872_77719219 0.16 ENSG00000238769
 .
 162240
 0.04
chr19_56109651_56109802 0.16 FIZ1
 FLT3-interacting zinc finger 1
 428
 0.61
chr3_189826682_189826960 0.16 ENSG00000265045
 .
 4902
 0.18
chr3_120364035_120364285 0.16 HGD
 homogentisate 1,2-dioxygenase
 1022
 0.62
chr2_28615239_28615407 0.16 FOSL2
 FOS-like antigen 2
 346
 0.84
chr12_111074662_111075000 0.16 TCTN1
 tectonic family member 1
 4023
 0.17
chr19_41857694_41857871 0.16 TMEM91
 transmembrane protein 91
 966
 0.33
chr19_55720445_55720596 0.16 PTPRH
 protein tyrosine phosphatase, receptor type, H
 304
 0.77
chr22_45622079_45622539 0.16 KIAA0930
 KIAA0930
 475
 0.8
chr22_18452853_18453098 0.16 ENSG00000207780
 .
 10752
 0.16
chr17_48233037_48233205 0.16 PPP1R9B
 protein phosphatase 1, regulatory subunit 9B
 5244
 0.1
chr5_169064615_169064766 0.16 DOCK2
 dedicator of cytokinesis 2
 439
 0.88
chr10_89577780_89577931 0.16 ATAD1
 ATPase family, AAA domain containing 1
 62
 0.97
chr1_55008801_55008989 0.16 ACOT11
 acyl-CoA thioesterase 11
 5006
 0.19
chr2_66803103_66803386 0.16 MEIS1
 Meis homeobox 1
 67185
 0.13
chr5_68389500_68389651 0.16 SLC30A5
 solute carrier family 30 (zinc transporter), member 5
 102
 0.97
chr17_1080828_1080990 0.15 ABR
 active BCR-related
 2169
 0.3
chr19_15333671_15333847 0.15 EPHX3
 epoxide hydrolase 3
 9484
 0.16
chr12_124508725_124508964 0.15 ZNF664
 zinc finger protein 664
 51002
 0.07
chr10_45455297_45455490 0.15 RASSF4
 Ras association (RalGDS/AF-6) domain family member 4
 114
 0.63
chr15_39802419_39802570 0.15 THBS1
 thrombospondin 1
 70786
 0.1
chr3_85008969_85009125 0.15 CADM2
 cell adhesion molecule 2
 350
 0.93
chr5_149883084_149883321 0.15 NDST1
 N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1
 4472
 0.21
chr17_48501944_48502107 0.15 ACSF2
 acyl-CoA synthetase family member 2
 1494
 0.25
chr2_182715012_182715242 0.15 RP11-366L5.1
41263
 0.15
chr8_129197888_129198179 0.15 ENSG00000201782
 .
 34717
 0.18
chr20_43987047_43987198 0.15 SYS1
 SYS1 Golgi-localized integral membrane protein homolog (S. cerevisiae)
 3455
 0.15
chr10_101283342_101283569 0.15 RP11-129J12.2
3745
 0.22
chr16_12552047_12552229 0.15 RP11-165M1.2
85458
 0.07
chr11_126152650_126152801 0.15 TIRAP
 toll-interleukin 1 receptor (TIR) domain containing adaptor protein
 257
 0.79
chr12_109089717_109090214 0.15 CORO1C
 coronin, actin binding protein, 1C
 213
 0.92
chr6_42110106_42110370 0.15 C6orf132
 chromosome 6 open reading frame 132
 56
 0.97
chr10_74034261_74034412 0.15 DDIT4
 DNA-damage-inducible transcript 4
 658
 0.58
chr10_75758429_75758627 0.15 VCL
 vinculin
 654
 0.69
chr7_23401357_23401759 0.15 ENSG00000212264
 .
 34507
 0.16
chr19_1667467_1667618 0.15 TCF3
 transcription factor 3
 14938
 0.12
chr12_51781847_51782170 0.15 GALNT6
 UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 6 (GalNAc-T6)
 3075
 0.2
chr18_46247007_46247395 0.15 RP11-426J5.2
32411
 0.19
chr15_43478099_43478250 0.15 CCNDBP1
 cyclin D-type binding-protein 1
 537
 0.55
chr1_229364834_229364985 0.15 RP5-1061H20.5
1600
 0.36
chr10_44806204_44806393 0.15 RP11-20J15.3
17141
 0.24
chr13_42615279_42615552 0.15 DGKH
 diacylglycerol kinase, eta
 1239
 0.48
chr3_12044959_12045206 0.15 ENSG00000263988
 .
 50523
 0.15
chr14_23289177_23289429 0.15 SLC7A7
 solute carrier family 7 (amino acid transporter light chain, y+L system), member 7
 283
 0.79
chr17_48049156_48049307 0.15 DLX4
 distal-less homeobox 4
 899
 0.52
chr9_114659712_114659863 0.15 UGCG
 UDP-glucose ceramide glucosyltransferase
 741
 0.68
chr4_1754002_1754153 0.15 TACC3
 transforming, acidic coiled-coil containing protein 3
 23946
 0.13
chr15_70434952_70435153 0.15 TLE3
 transducin-like enhancer of split 3 (E(sp1) homolog, Drosophila)
 44537
 0.16
chr20_43590008_43590159 0.15 TOMM34
 translocase of outer mitochondrial membrane 34
 956
 0.48
chr10_104389202_104389369 0.14 TRIM8
 tripartite motif containing 8
 14968
 0.16
chrX_39964958_39965304 0.14 BCOR
 BCL6 corepressor
 8475
 0.32
chr6_3624272_3624465 0.14 PXDC1
 PX domain containing 1
 114760
 0.06
chr20_3758571_3758722 0.14 SPEF1
 sperm flagellar 1
 3449
 0.15
chr17_27894487_27894949 0.14 TP53I13
 tumor protein p53 inducible protein 13
 327
 0.58
chr21_30617757_30617942 0.14 BACH1
 BTB and CNC homology 1, basic leucine zipper transcription factor 1
 51381
 0.1
chr6_7431781_7431972 0.14 CAGE1
 cancer antigen 1
 41900
 0.15
chr1_11796539_11796690 0.14 AGTRAP
 angiotensin II receptor-associated protein
 382
 0.79
chr1_208137980_208138131 0.14 CD34
 CD34 molecule
 53308
 0.17
chr1_3050486_3050709 0.14 RP1-163G9.2
324
 0.92
chr21_36042164_36042315 0.14 CLIC6
 chloride intracellular channel 6
 551
 0.82
chr11_67781609_67782080 0.14 ALDH3B1
 aldehyde dehydrogenase 3 family, member B1
 4054
 0.13
chr19_56620271_56620526 0.14 ENSG00000223060
 .
 3613
 0.16
chr9_5846170_5846325 0.14 ERMP1
 endoplasmic reticulum metallopeptidase 1
 13130
 0.19
chr18_77138968_77139119 0.14 NFATC1
 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1
 16813
 0.2
chr8_103255015_103255398 0.14 KB-431C1.4
631
 0.67
chr3_85007560_85007788 0.14 CADM2
 cell adhesion molecule 2
 458
 0.89
chr9_124985233_124985384 0.14 LHX6
 LIM homeobox 6
 1289
 0.37
chr4_75240215_75240456 0.14 EREG
 epiregulin
 9475
 0.2
chr3_177651904_177652275 0.14 ENSG00000199858
 .
 73478
 0.13
chr9_694654_694862 0.14 RP11-130C19.3
9203
 0.22
chr4_10126213_10126364 0.14 WDR1
 WD repeat domain 1
 7715
 0.18
chr1_26145213_26145423 0.14 MTFR1L
 mitochondrial fission regulator 1-like
 187
 0.83
chr5_36241274_36241468 0.14 NADK2
 NAD kinase 2, mitochondrial
 122
 0.96
chr22_45095245_45095396 0.14 PRR5
 proline rich 5 (renal)
 2758
 0.23
chr11_27723424_27723575 0.14 BDNF
 brain-derived neurotrophic factor
 319
 0.92
chr1_203155609_203155963 0.14 CHI3L1
 chitinase 3-like 1 (cartilage glycoprotein-39)
 91
 0.96
chr11_12790666_12790817 0.14 TEAD1
 TEA domain family member 1 (SV40 transcriptional enhancer factor)
 24153
 0.21
chr16_68334547_68335007 0.14 SLC7A6OS
 solute carrier family 7, member 6 opposite strand
 3355
 0.11
chr1_48937375_48937526 0.14 SPATA6
 spermatogenesis associated 6
 232
 0.95
chr16_57671558_57671817 0.14 GPR56
 G protein-coupled receptor 56
 1520
 0.31
chr4_86935791_86936081 0.14 RP13-514E23.1
909
 0.62
chr10_105211829_105211980 0.14 CALHM2
 calcium homeostasis modulator 2
 171
 0.82
chr6_163681290_163681441 0.14 ENSG00000239136
 .
 33423
 0.21
chr11_44971760_44972074 0.14 TP53I11
 tumor protein p53 inducible protein 11
 158
 0.97
chr3_159903422_159903573 0.13 IL12A-AS1
 IL12A antisense RNA 1
 21382
 0.18
chr10_49815677_49815878 0.13 ARHGAP22
 Rho GTPase activating protein 22
 2639
 0.3
chr6_163776181_163776490 0.13 QKI
 QKI, KH domain containing, RNA binding
 59340
 0.15
chr12_26380208_26380359 0.13 SSPN
 sarcospan
 31677
 0.16
chr7_150659770_150659921 0.13 KCNH2
 potassium voltage-gated channel, subfamily H (eag-related), member 2
 1881
 0.27
chr12_124877793_124878051 0.13 NCOR2
 nuclear receptor corepressor 2
 4552
 0.32
chr11_1913396_1913650 0.13 C11orf89
 chromosome 11 open reading frame 89
 1439
 0.25
chr1_28517417_28517723 0.13 PTAFR
 platelet-activating factor receptor
 2814
 0.15
chr20_3652796_3652947 0.13 GFRA4
 GDNF family receptor alpha 4
 8825
 0.15
chr2_172945273_172945521 0.13 DLX1
 distal-less homeobox 1
 4071
 0.25
chr1_50888417_50888568 0.13 DMRTA2
 DMRT-like family A2
 680
 0.75
chr6_15276422_15276621 0.13 JARID2
 jumonji, AT rich interactive domain 2
 27378
 0.16
chr17_39942503_39942654 0.13 JUP
 junction plakoglobin
 117
 0.93
chr21_47603648_47603799 0.13 SPATC1L
 spermatogenesis and centriole associated 1-like
 650
 0.46
chr5_139034464_139034615 0.13 CXXC5
 CXXC finger protein 5
 3965
 0.26
chr17_8383287_8383438 0.13 NDEL1
 nudE neurodevelopment protein 1-like 1
 29263
 0.12
chr8_28347877_28348093 0.13 FBXO16
 F-box protein 16
 150
 0.94
chr10_80938884_80939035 0.13 ZMIZ1
 zinc finger, MIZ-type containing 1
 110167
 0.06
chr6_21847212_21847442 0.13 ENSG00000222515
 .
 238446
 0.02
chr8_8408574_8408871 0.13 ENSG00000263616
 .
 31443
 0.21
chr1_19639347_19639591 0.13 PQLC2
 PQ loop repeat containing 2
 634
 0.43
chr12_132337369_132337604 0.13 MMP17
 matrix metallopeptidase 17 (membrane-inserted)
 7646
 0.18
chr15_26084539_26084690 0.13 ENSG00000266517
 .
 9358
 0.19
chr6_41754836_41755024 0.13 TOMM6
 translocase of outer mitochondrial membrane 6 homolog (yeast)
 470
 0.49
chr16_29616402_29616553 0.13 ENSG00000266758
 .
 5891
 0.16
chr15_77707876_77708432 0.13 PEAK1
 pseudopodium-enriched atypical kinase 1
 4288
 0.26
chr12_7126708_7126912 0.13 LPCAT3
 lysophosphatidylcholine acyltransferase 3
 996
 0.35
chr3_59761256_59761407 0.13 NPCDR1
 nasopharyngeal carcinoma, down-regulated 1
 196252
 0.03
chr2_242499276_242499525 0.13 BOK-AS1
 BOK antisense RNA 1
 1008
 0.35
chrX_54948494_54948718 0.13 TRO
 trophinin
 196
 0.94
chr5_172266910_172267216 0.13 ERGIC1
 endoplasmic reticulum-golgi intermediate compartment (ERGIC) 1
 5649
 0.2
chr10_45474416_45474772 0.13 C10orf10
 chromosome 10 open reading frame 10
 336
 0.82
chr3_16006227_16006629 0.13 ENSG00000207815
 .
 91150
 0.08
chr19_13905830_13905981 0.13 ZSWIM4
 zinc finger, SWIM-type containing 4
 369
 0.68
chr2_172380569_172381265 0.13 CYBRD1
 cytochrome b reductase 1
 1328
 0.53
chr1_206845534_206845685 0.13 ENSG00000252853
 .
 9699
 0.14
chr19_4878563_4878757 0.13 ENSG00000264899
 .
 1936
 0.21
chr5_692826_693134 0.13 TPPP
 tubulin polymerization promoting protein
 530
 0.74
chr3_194600486_194600791 0.13 FAM43A
 family with sequence similarity 43, member A
 194016
 0.02
chr1_36786899_36787105 0.13 RP11-268J15.5
2333
 0.2
chr5_158179607_158179937 0.13 CTD-2363C16.1
230242
 0.02
chr22_37416048_37416272 0.13 MPST
 mercaptopyruvate sulfurtransferase
 347
 0.54
chr4_57909352_57909761 0.13 ENSG00000251703
 .
 40698
 0.11
chr20_50180187_50180357 0.13 NFATC2
 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2
 902
 0.72
chr17_78237788_78237939 0.13 RNF213
 ring finger protein 213
 3194
 0.2
chr12_106695790_106695941 0.13 TCP11L2
 t-complex 11, testis-specific-like 2
 158
 0.94
chr11_76411277_76411428 0.13 GUCY2EP
 guanylate cyclase 2E, pseudogene
 7333
 0.18
chr6_56517195_56517397 0.12 DST
 dystonin
 9502
 0.31
chr14_29254769_29255066 0.12 RP11-966I7.2
76
 0.97
chr2_217354341_217354722 0.12 AC098820.4
2612
 0.22
chr2_29678241_29678392 0.12 ENSG00000266310
 .
 48543
 0.18
chr22_36822490_36822658 0.12 ENSG00000252575
 .
 12397
 0.15
chr7_5632818_5633083 0.12 FSCN1
 fascin homolog 1, actin-bundling protein (Strongylocentrotus purpuratus)
 496
 0.76
chr7_5595160_5595387 0.12 CTB-161C1.1
1089
 0.41
chr12_113298325_113298476 0.12 RPH3A
 rabphilin 3A homolog (mouse)
 32276
 0.17
chr1_64626493_64626644 0.12 RP11-24J23.2
10412
 0.21
chr5_123964374_123964729 0.12 RP11-436H11.2
99973
 0.06
chr17_46012490_46012796 0.12 RP11-6N17.3
2171
 0.16
chr12_50020089_50020240 0.12 PRPF40B
 PRP40 pre-mRNA processing factor 40 homolog B (S. cerevisiae)
 2761
 0.2
chr18_46422994_46423234 0.12 SMAD7
 SMAD family member 7
 51761
 0.14
chr1_41290137_41290288 0.12 KCNQ4
 potassium voltage-gated channel, KQT-like subfamily, member 4
 7275
 0.15
chr3_149095823_149096214 0.12 TM4SF1-AS1
 TM4SF1 antisense RNA 1
 12
 0.86
chr4_87889842_87889993 0.12 AFF1
 AF4/FMR2 family, member 1
 32355
 0.19
chr10_104380767_104380980 0.12 TRIM8
 tripartite motif containing 8
 23380
 0.14
chr10_126707561_126707832 0.12 CTBP2
 C-terminal binding protein 2
 8763
 0.2

Histogram of CRE-TSS distances for CREs targeted by :

Histogram of

Rank distribution of CRE target scores:

Histogram of target CRE score.

Distribution of target CREs across different genomic regions:

Weighted Piechart of Weighted Piechart of Weighted Piechart of

Network of associatons between targets according to the STRING database.

StringDB image

First level regulatory network of NR0B1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0031061 negative regulation of histone methylation(GO:0031061)
0.1 0.2 GO:0007028 cytoplasm organization(GO:0007028)
0.1 0.2 GO:0060831 smoothened signaling pathway involved in dorsal/ventral neural tube patterning(GO:0060831)
0.0 0.1 GO:0003215 cardiac right ventricle morphogenesis(GO:0003215)
0.0 0.1 GO:0034135 regulation of toll-like receptor 2 signaling pathway(GO:0034135)
0.0 0.3 GO:0090136 epithelial cell-cell adhesion(GO:0090136)
0.0 0.2 GO:0034063 stress granule assembly(GO:0034063)
0.0 0.0 GO:0007621 negative regulation of female receptivity(GO:0007621)
0.0 0.2 GO:1904181 positive regulation of mitochondrial depolarization(GO:0051901) positive regulation of membrane depolarization(GO:1904181)
0.0 0.0 GO:0046083 adenine salvage(GO:0006168) purine nucleobase salvage(GO:0043096) adenine metabolic process(GO:0046083) adenine biosynthetic process(GO:0046084)
0.0 0.2 GO:0045647 negative regulation of erythrocyte differentiation(GO:0045647)
0.0 0.1 GO:0032071 regulation of endodeoxyribonuclease activity(GO:0032071)
0.0 0.3 GO:0021799 cerebral cortex radially oriented cell migration(GO:0021799)
0.0 0.1 GO:0048702 embryonic neurocranium morphogenesis(GO:0048702)
0.0 0.1 GO:0010193 response to ozone(GO:0010193)
0.0 0.1 GO:0007386 compartment pattern specification(GO:0007386)
0.0 0.2 GO:0045793 positive regulation of cell size(GO:0045793)
0.0 0.2 GO:0006824 cobalt ion transport(GO:0006824)
0.0 0.1 GO:0003010 voluntary skeletal muscle contraction(GO:0003010) twitch skeletal muscle contraction(GO:0014721)
0.0 0.2 GO:0006198 cAMP catabolic process(GO:0006198)
0.0 0.2 GO:0046855 phosphorylated carbohydrate dephosphorylation(GO:0046838) inositol phosphate dephosphorylation(GO:0046855)
0.0 0.1 GO:0045722 positive regulation of gluconeogenesis(GO:0045722)
0.0 0.1 GO:0021569 rhombomere 3 development(GO:0021569)
0.0 0.1 GO:0002085 inhibition of neuroepithelial cell differentiation(GO:0002085)
0.0 0.1 GO:0070777 D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
0.0 0.1 GO:0072393 microtubule anchoring at microtubule organizing center(GO:0072393)
0.0 0.1 GO:0046599 regulation of centriole replication(GO:0046599)
0.0 0.1 GO:0071436 sodium ion export(GO:0071436)
0.0 0.1 GO:0001766 membrane raft polarization(GO:0001766) membrane raft distribution(GO:0031580)
0.0 0.1 GO:0071318 cellular response to ATP(GO:0071318)
0.0 0.2 GO:0032957 inositol trisphosphate metabolic process(GO:0032957)
0.0 0.1 GO:0070561 vitamin D receptor signaling pathway(GO:0070561)
0.0 0.1 GO:0006003 fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.0 0.1 GO:0070874 negative regulation of glycogen metabolic process(GO:0070874)
0.0 0.1 GO:0051503 adenine nucleotide transport(GO:0051503)
0.0 0.1 GO:0006565 L-serine catabolic process(GO:0006565)
0.0 0.1 GO:0090206 negative regulation of cholesterol biosynthetic process(GO:0045541) negative regulation of cholesterol metabolic process(GO:0090206)
0.0 0.1 GO:0006925 inflammatory cell apoptotic process(GO:0006925)
0.0 0.1 GO:0002407 dendritic cell chemotaxis(GO:0002407) dendritic cell migration(GO:0036336)
0.0 0.2 GO:0045662 negative regulation of myoblast differentiation(GO:0045662)
0.0 0.1 GO:0060586 multicellular organismal iron ion homeostasis(GO:0060586)
0.0 0.1 GO:0060789 hair follicle placode formation(GO:0060789)
0.0 0.1 GO:0042637 catagen(GO:0042637)
0.0 0.1 GO:0046697 decidualization(GO:0046697)
0.0 0.4 GO:0043392 negative regulation of DNA binding(GO:0043392)
0.0 0.1 GO:0090292 nuclear matrix organization(GO:0043578) nuclear matrix anchoring at nuclear membrane(GO:0090292)
0.0 0.1 GO:0042816 pyridoxine metabolic process(GO:0008614) pyridoxine biosynthetic process(GO:0008615) vitamin B6 metabolic process(GO:0042816) vitamin B6 biosynthetic process(GO:0042819)
0.0 0.1 GO:0060083 smooth muscle contraction involved in micturition(GO:0060083)
0.0 0.0 GO:0033505 floor plate formation(GO:0021508) floor plate morphogenesis(GO:0033505)
0.0 0.0 GO:0010980 regulation of vitamin D 24-hydroxylase activity(GO:0010979) positive regulation of vitamin D 24-hydroxylase activity(GO:0010980)
0.0 0.1 GO:0051964 negative regulation of synapse assembly(GO:0051964)
0.0 0.3 GO:0034605 cellular response to heat(GO:0034605)
0.0 0.1 GO:0046831 regulation of RNA export from nucleus(GO:0046831)
0.0 0.1 GO:0002328 pro-B cell differentiation(GO:0002328)
0.0 0.1 GO:0010766 negative regulation of sodium ion transport(GO:0010766)
0.0 0.1 GO:0010586 miRNA metabolic process(GO:0010586) miRNA catabolic process(GO:0010587)
0.0 0.1 GO:0042832 defense response to protozoan(GO:0042832)
0.0 0.1 GO:0032277 negative regulation of gonadotropin secretion(GO:0032277)
0.0 0.1 GO:0045759 negative regulation of action potential(GO:0045759)
0.0 0.1 GO:0009186 deoxyribonucleoside diphosphate metabolic process(GO:0009186)
0.0 0.1 GO:0046476 glycosylceramide biosynthetic process(GO:0046476)
0.0 0.1 GO:0072148 epithelial cell fate commitment(GO:0072148)
0.0 0.1 GO:0061030 epithelial cell differentiation involved in mammary gland alveolus development(GO:0061030)
0.0 0.0 GO:0033688 regulation of osteoblast proliferation(GO:0033688)
0.0 0.1 GO:0014049 positive regulation of glutamate secretion(GO:0014049)
0.0 0.0 GO:0044240 multicellular organism lipid catabolic process(GO:0044240)
0.0 0.1 GO:0006435 threonyl-tRNA aminoacylation(GO:0006435)
0.0 0.1 GO:0071072 negative regulation of phospholipid biosynthetic process(GO:0071072)
0.0 0.1 GO:0006572 tyrosine catabolic process(GO:0006572)
0.0 0.0 GO:0070837 dehydroascorbic acid transport(GO:0070837)
0.0 0.1 GO:0043497 regulation of protein heterodimerization activity(GO:0043497)
0.0 0.1 GO:0043116 negative regulation of vascular permeability(GO:0043116)
0.0 0.1 GO:0048149 behavioral response to ethanol(GO:0048149)
0.0 0.1 GO:0048172 regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.0 0.1 GO:0019720 Mo-molybdopterin cofactor biosynthetic process(GO:0006777) Mo-molybdopterin cofactor metabolic process(GO:0019720) molybdopterin cofactor biosynthetic process(GO:0032324) molybdopterin cofactor metabolic process(GO:0043545) prosthetic group metabolic process(GO:0051189)
0.0 0.1 GO:0007216 G-protein coupled glutamate receptor signaling pathway(GO:0007216)
0.0 0.0 GO:0072201 negative regulation of mesenchymal cell proliferation(GO:0072201)
0.0 0.0 GO:0060298 positive regulation of sarcomere organization(GO:0060298)
0.0 0.1 GO:0006419 alanyl-tRNA aminoacylation(GO:0006419)
0.0 0.1 GO:0001547 antral ovarian follicle growth(GO:0001547)
0.0 0.1 GO:0070120 ciliary neurotrophic factor-mediated signaling pathway(GO:0070120)
0.0 0.1 GO:0017182 peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183)
0.0 0.1 GO:0070059 intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress(GO:0070059)
0.0 0.1 GO:2000178 negative regulation of neuroblast proliferation(GO:0007406) negative regulation of neural precursor cell proliferation(GO:2000178)
0.0 0.0 GO:0031558 obsolete induction of apoptosis in response to chemical stimulus(GO:0031558)
0.0 0.0 GO:0001821 histamine secretion(GO:0001821)
0.0 0.1 GO:0021548 pons development(GO:0021548)
0.0 0.1 GO:0060501 positive regulation of epithelial cell proliferation involved in lung morphogenesis(GO:0060501) regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000794)
0.0 0.1 GO:0017121 phospholipid scrambling(GO:0017121)
0.0 0.0 GO:0048368 lateral mesoderm development(GO:0048368)
0.0 0.0 GO:0046940 nucleoside monophosphate phosphorylation(GO:0046940)
0.0 0.0 GO:0019049 evasion or tolerance of host defenses by virus(GO:0019049) avoidance of host defenses(GO:0044413) evasion or tolerance of host defenses(GO:0044415) avoidance of defenses of other organism involved in symbiotic interaction(GO:0051832) evasion or tolerance of defenses of other organism involved in symbiotic interaction(GO:0051834)
0.0 0.1 GO:0002093 auditory receptor cell morphogenesis(GO:0002093) auditory receptor cell stereocilium organization(GO:0060088)
0.0 0.1 GO:0043457 regulation of cellular respiration(GO:0043457)
0.0 0.1 GO:0009051 pentose-phosphate shunt, oxidative branch(GO:0009051)
0.0 0.0 GO:0003099 positive regulation of the force of heart contraction by chemical signal(GO:0003099)
0.0 0.0 GO:0030540 female genitalia development(GO:0030540)
0.0 0.1 GO:0032467 positive regulation of cytokinesis(GO:0032467)
0.0 0.0 GO:0033024 mast cell homeostasis(GO:0033023) mast cell apoptotic process(GO:0033024) regulation of mast cell apoptotic process(GO:0033025)
0.0 0.1 GO:0042271 susceptibility to natural killer cell mediated cytotoxicity(GO:0042271)
0.0 0.0 GO:0014041 regulation of neuron maturation(GO:0014041) regulation of cell maturation(GO:1903429)
0.0 0.0 GO:0051005 negative regulation of lipoprotein lipase activity(GO:0051005)
0.0 0.0 GO:0061047 foregut regionalization(GO:0060423) lung field specification(GO:0060424) lung induction(GO:0060492) positive regulation of branching involved in lung morphogenesis(GO:0061047)
0.0 0.1 GO:0050847 progesterone receptor signaling pathway(GO:0050847)
0.0 0.1 GO:0042448 progesterone metabolic process(GO:0042448)
0.0 0.0 GO:0045112 integrin biosynthetic process(GO:0045112)
0.0 0.1 GO:0006931 substrate-dependent cell migration, cell attachment to substrate(GO:0006931)
0.0 0.1 GO:0032020 ISG15-protein conjugation(GO:0032020)
0.0 0.0 GO:0048840 otolith development(GO:0048840)
0.0 0.0 GO:0010957 negative regulation of calcidiol 1-monooxygenase activity(GO:0010956) negative regulation of vitamin D biosynthetic process(GO:0010957) negative regulation of vitamin metabolic process(GO:0046137)
0.0 0.1 GO:0060394 negative regulation of pathway-restricted SMAD protein phosphorylation(GO:0060394)
0.0 0.0 GO:0003352 regulation of cilium movement(GO:0003352) regulation of cilium beat frequency(GO:0003356) cilium movement involved in cell motility(GO:0060294) regulation of cilium movement involved in cell motility(GO:0060295) regulation of cilium beat frequency involved in ciliary motility(GO:0060296) regulation of cilium-dependent cell motility(GO:1902019)
0.0 0.0 GO:0010757 negative regulation of plasminogen activation(GO:0010757)
0.0 0.0 GO:0071545 inositol phosphate catabolic process(GO:0071545)
0.0 0.1 GO:0060732 positive regulation of inositol phosphate biosynthetic process(GO:0060732)
0.0 0.0 GO:0045007 depurination(GO:0045007)
0.0 0.0 GO:0030091 protein repair(GO:0030091)
0.0 0.1 GO:0035162 embryonic hemopoiesis(GO:0035162)
0.0 0.0 GO:0043951 negative regulation of cAMP-mediated signaling(GO:0043951)
0.0 0.4 GO:0048146 positive regulation of fibroblast proliferation(GO:0048146)
0.0 0.0 GO:0018119 protein nitrosylation(GO:0017014) peptidyl-cysteine S-nitrosylation(GO:0018119)
0.0 0.1 GO:0046337 phosphatidylethanolamine biosynthetic process(GO:0006646) phosphatidylethanolamine metabolic process(GO:0046337)
0.0 0.0 GO:0021615 glossopharyngeal nerve development(GO:0021563) glossopharyngeal nerve morphogenesis(GO:0021615)
0.0 0.1 GO:0031115 negative regulation of microtubule polymerization(GO:0031115)
0.0 0.2 GO:0048844 artery morphogenesis(GO:0048844)
0.0 0.0 GO:0060648 mammary gland bud morphogenesis(GO:0060648)
0.0 0.0 GO:0042339 keratan sulfate metabolic process(GO:0042339)
0.0 0.0 GO:0002043 blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:0002043)
0.0 0.0 GO:0071277 cellular response to calcium ion(GO:0071277)
0.0 0.0 GO:0009756 carbohydrate mediated signaling(GO:0009756)
0.0 0.0 GO:0072143 mesangial cell differentiation(GO:0072007) kidney interstitial fibroblast differentiation(GO:0072071) renal interstitial fibroblast development(GO:0072141) mesangial cell development(GO:0072143) pericyte cell differentiation(GO:1904238)
0.0 0.0 GO:0060157 urinary bladder development(GO:0060157)
0.0 0.0 GO:0070366 regulation of hepatocyte differentiation(GO:0070366)
0.0 0.0 GO:0016559 peroxisome fission(GO:0016559)
0.0 0.1 GO:0060155 platelet dense granule organization(GO:0060155)
0.0 0.0 GO:0030644 cellular chloride ion homeostasis(GO:0030644) chloride ion homeostasis(GO:0055064)
0.0 0.0 GO:0002689 negative regulation of leukocyte chemotaxis(GO:0002689)
0.0 0.0 GO:0060762 regulation of branching involved in mammary gland duct morphogenesis(GO:0060762)
0.0 0.0 GO:0032291 central nervous system myelination(GO:0022010) axon ensheathment in central nervous system(GO:0032291)
0.0 0.2 GO:0046415 urate metabolic process(GO:0046415)
0.0 0.1 GO:0009886 post-embryonic morphogenesis(GO:0009886)
0.0 0.0 GO:0042536 negative regulation of tumor necrosis factor biosynthetic process(GO:0042536)
0.0 0.0 GO:1903299 regulation of glucokinase activity(GO:0033131) positive regulation of glucokinase activity(GO:0033133) regulation of hexokinase activity(GO:1903299) positive regulation of hexokinase activity(GO:1903301)
0.0 0.1 GO:0043276 anoikis(GO:0043276)
0.0 0.0 GO:0016576 histone dephosphorylation(GO:0016576)
0.0 0.1 GO:0046457 prostaglandin biosynthetic process(GO:0001516) prostanoid biosynthetic process(GO:0046457)
0.0 0.2 GO:0042490 mechanoreceptor differentiation(GO:0042490)
0.0 0.0 GO:0032525 somite rostral/caudal axis specification(GO:0032525)
0.0 0.0 GO:0071542 dopaminergic neuron differentiation(GO:0071542)
0.0 0.0 GO:0072338 allantoin metabolic process(GO:0000255) creatinine metabolic process(GO:0046449) cellular lactam metabolic process(GO:0072338)
0.0 0.2 GO:0001706 endoderm formation(GO:0001706)
0.0 0.0 GO:0007181 transforming growth factor beta receptor complex assembly(GO:0007181)
0.0 0.0 GO:0021794 thalamus development(GO:0021794)
0.0 0.1 GO:0019985 translesion synthesis(GO:0019985)
0.0 0.0 GO:0008053 mitochondrial fusion(GO:0008053)
0.0 0.0 GO:1903726 negative regulation of phospholipid metabolic process(GO:1903726)
0.0 0.0 GO:2000328 T-helper cell lineage commitment(GO:0002295) alpha-beta T cell lineage commitment(GO:0002363) CD4-positive, alpha-beta T cell lineage commitment(GO:0043373) memory T cell differentiation(GO:0043379) regulation of memory T cell differentiation(GO:0043380) positive regulation of memory T cell differentiation(GO:0043382) T-helper 17 type immune response(GO:0072538) T-helper 17 cell differentiation(GO:0072539) T-helper 17 cell lineage commitment(GO:0072540) regulation of T-helper 17 type immune response(GO:2000316) positive regulation of T-helper 17 type immune response(GO:2000318) regulation of T-helper 17 cell differentiation(GO:2000319) positive regulation of T-helper 17 cell differentiation(GO:2000321) regulation of T-helper 17 cell lineage commitment(GO:2000328) positive regulation of T-helper 17 cell lineage commitment(GO:2000330)
0.0 0.1 GO:0019369 arachidonic acid metabolic process(GO:0019369)
0.0 0.1 GO:0042574 retinal metabolic process(GO:0042574)
0.0 0.1 GO:1901976 regulation of cell cycle checkpoint(GO:1901976)
0.0 0.1 GO:0009125 nucleoside monophosphate catabolic process(GO:0009125)
0.0 0.1 GO:0006032 chitin metabolic process(GO:0006030) chitin catabolic process(GO:0006032)
0.0 0.0 GO:0048312 intracellular distribution of mitochondria(GO:0048312)
0.0 0.0 GO:0034421 post-translational protein acetylation(GO:0034421)
0.0 0.0 GO:0032509 endosome transport via multivesicular body sorting pathway(GO:0032509)
0.0 0.1 GO:0030033 microvillus assembly(GO:0030033) microvillus organization(GO:0032528)
0.0 0.1 GO:0019367 fatty acid elongation, saturated fatty acid(GO:0019367)
0.0 0.0 GO:0044314 protein K27-linked ubiquitination(GO:0044314)
0.0 0.0 GO:0072133 kidney mesenchyme morphogenesis(GO:0072131) metanephric mesenchyme morphogenesis(GO:0072133)
0.0 0.1 GO:0030174 regulation of DNA-dependent DNA replication initiation(GO:0030174)
0.0 0.0 GO:0032632 interleukin-3 production(GO:0032632)
0.0 0.0 GO:0030011 maintenance of cell polarity(GO:0030011)
0.0 0.1 GO:0002829 negative regulation of type 2 immune response(GO:0002829)
0.0 0.0 GO:0072526 pyridine-containing compound catabolic process(GO:0072526)
0.0 0.1 GO:0040015 negative regulation of multicellular organism growth(GO:0040015)
0.0 0.0 GO:0060666 dichotomous subdivision of terminal units involved in salivary gland branching(GO:0060666)
0.0 0.0 GO:0085020 protein K6-linked ubiquitination(GO:0085020)
0.0 0.0 GO:0090009 primitive streak formation(GO:0090009)
0.0 0.1 GO:0090083 regulation of inclusion body assembly(GO:0090083)
0.0 0.0 GO:0010823 negative regulation of mitochondrion organization(GO:0010823) negative regulation of release of cytochrome c from mitochondria(GO:0090201) negative regulation of apoptotic signaling pathway(GO:2001234)
0.0 0.1 GO:0060216 definitive hemopoiesis(GO:0060216)
0.0 0.1 GO:0046487 glyoxylate metabolic process(GO:0046487)
0.0 0.1 GO:0030321 transepithelial chloride transport(GO:0030321)
0.0 0.1 GO:0032410 negative regulation of transporter activity(GO:0032410)
0.0 0.1 GO:0050872 white fat cell differentiation(GO:0050872)
0.0 0.0 GO:0010107 potassium ion import(GO:0010107)
0.0 0.0 GO:0045657 positive regulation of monocyte differentiation(GO:0045657)
0.0 0.1 GO:0015074 DNA integration(GO:0015074)
0.0 0.0 GO:0048388 endosomal lumen acidification(GO:0048388)
0.0 0.2 GO:0007566 embryo implantation(GO:0007566)
0.0 0.1 GO:0042976 activation of Janus kinase activity(GO:0042976)
0.0 0.2 GO:0006636 unsaturated fatty acid biosynthetic process(GO:0006636)
0.0 0.0 GO:0033137 negative regulation of peptidyl-serine phosphorylation(GO:0033137)
0.0 0.0 GO:0060014 granulosa cell differentiation(GO:0060014)
0.0 0.0 GO:0051124 synaptic growth at neuromuscular junction(GO:0051124)
0.0 0.0 GO:0034379 very-low-density lipoprotein particle assembly(GO:0034379)
0.0 0.0 GO:0019227 neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870)
0.0 0.1 GO:0060263 regulation of respiratory burst(GO:0060263)
0.0 0.1 GO:0001561 fatty acid alpha-oxidation(GO:0001561)
0.0 0.0 GO:0070682 proteasome regulatory particle assembly(GO:0070682)
0.0 0.2 GO:0072332 intrinsic apoptotic signaling pathway by p53 class mediator(GO:0072332)
0.0 0.1 GO:0042989 sequestering of actin monomers(GO:0042989)
0.0 0.1 GO:0007141 male meiosis I(GO:0007141)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 GO:0005915 zonula adherens(GO:0005915)
0.0 0.1 GO:0030008 TRAPP complex(GO:0030008)
0.0 0.1 GO:0030934 anchoring collagen complex(GO:0030934)
0.0 0.2 GO:0031512 motile primary cilium(GO:0031512)
0.0 0.2 GO:0005916 fascia adherens(GO:0005916)
0.0 0.1 GO:0005945 6-phosphofructokinase complex(GO:0005945)
0.0 0.1 GO:0033553 rDNA heterochromatin(GO:0033553)
0.0 0.1 GO:0005862 muscle thin filament tropomyosin(GO:0005862)
0.0 0.1 GO:0044453 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229) nuclear membrane part(GO:0044453)
0.0 0.1 GO:0031332 RISC complex(GO:0016442) RNAi effector complex(GO:0031332)
0.0 0.1 GO:0016533 cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533)
0.0 0.1 GO:0032809 neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.0 0.1 GO:0005588 collagen type V trimer(GO:0005588)
0.0 0.1 GO:0005832 chaperonin-containing T-complex(GO:0005832)
0.0 0.1 GO:0031362 anchored component of external side of plasma membrane(GO:0031362)
0.0 0.1 GO:0032585 multivesicular body membrane(GO:0032585)
0.0 0.0 GO:0008282 ATP-sensitive potassium channel complex(GO:0008282)
0.0 0.1 GO:0031265 CD95 death-inducing signaling complex(GO:0031265)
0.0 0.1 GO:0005638 lamin filament(GO:0005638)
0.0 0.0 GO:0060200 clathrin-sculpted acetylcholine transport vesicle(GO:0060200) clathrin-sculpted acetylcholine transport vesicle membrane(GO:0060201)
0.0 0.0 GO:0034673 inhibin-betaglycan-ActRII complex(GO:0034673)
0.0 0.1 GO:0034992 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.0 0.2 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.0 0.1 GO:0002178 palmitoyltransferase complex(GO:0002178) serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211)
0.0 0.1 GO:0008274 gamma-tubulin large complex(GO:0000931) gamma-tubulin ring complex(GO:0008274)
0.0 0.1 GO:0030061 mitochondrial crista(GO:0030061)
0.0 0.1 GO:0048188 Set1C/COMPASS complex(GO:0048188)
0.0 0.1 GO:0043205 fibril(GO:0043205)
0.0 0.1 GO:0071204 histone pre-mRNA 3'end processing complex(GO:0071204)
0.0 0.2 GO:0030315 T-tubule(GO:0030315)
0.0 0.1 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
0.0 0.1 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.0 0.0 GO:0031205 endoplasmic reticulum Sec complex(GO:0031205)
0.0 0.1 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.0 0.1 GO:0033256 I-kappaB/NF-kappaB complex(GO:0033256)
0.0 0.0 GO:0005927 muscle tendon junction(GO:0005927)
0.0 0.2 GO:0031519 PcG protein complex(GO:0031519)
0.0 0.0 GO:0032444 activin responsive factor complex(GO:0032444)
0.0 0.1 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.0 0.1 GO:0005861 troponin complex(GO:0005861)
0.0 0.1 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.0 0.0 GO:0008537 proteasome activator complex(GO:0008537)
0.0 0.1 GO:0061200 clathrin-sculpted gamma-aminobutyric acid transport vesicle(GO:0061200) clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane(GO:0061202)
0.0 0.0 GO:0030056 hemidesmosome(GO:0030056)
0.0 0.0 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.0 0.0 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.0 0.1 GO:0071564 npBAF complex(GO:0071564)
0.0 0.1 GO:0071437 invadopodium(GO:0071437)
0.0 0.0 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.0 0.1 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0002162 dystroglycan binding(GO:0002162)
0.1 0.2 GO:0005432 calcium:sodium antiporter activity(GO:0005432)
0.1 0.2 GO:0030297 transmembrane receptor protein tyrosine kinase activator activity(GO:0030297)
0.0 0.1 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.0 0.1 GO:0043398 HLH domain binding(GO:0043398)
0.0 0.1 GO:0070576 vitamin D 24-hydroxylase activity(GO:0070576)
0.0 0.1 GO:0052659 inositol-1,4,5-trisphosphate 5-phosphatase activity(GO:0052658) inositol-1,3,4,5-tetrakisphosphate 5-phosphatase activity(GO:0052659)
0.0 0.2 GO:0004157 dihydropyrimidinase activity(GO:0004157)
0.0 0.1 GO:0052743 inositol tetrakisphosphate phosphatase activity(GO:0052743)
0.0 0.1 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.0 0.1 GO:0000293 ferric-chelate reductase activity(GO:0000293)
0.0 0.1 GO:0005250 A-type (transient outward) potassium channel activity(GO:0005250)
0.0 0.1 GO:0004748 ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
0.0 0.2 GO:0008330 protein tyrosine/threonine phosphatase activity(GO:0008330)
0.0 0.3 GO:0005112 Notch binding(GO:0005112)
0.0 0.2 GO:0030371 translation repressor activity(GO:0030371)
0.0 0.1 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
0.0 0.1 GO:0004792 thiosulfate sulfurtransferase activity(GO:0004792)
0.0 0.2 GO:0017154 semaphorin receptor activity(GO:0017154)
0.0 0.1 GO:0000987 RNA polymerase II core promoter proximal region sequence-specific DNA binding(GO:0000978) core promoter proximal region sequence-specific DNA binding(GO:0000987) core promoter proximal region DNA binding(GO:0001159)
0.0 0.1 GO:0003873 6-phosphofructo-2-kinase activity(GO:0003873)
0.0 0.1 GO:0033743 peptide-methionine (R)-S-oxide reductase activity(GO:0033743)
0.0 0.2 GO:0031994 insulin-like growth factor I binding(GO:0031994)
0.0 0.1 GO:0042608 T cell receptor binding(GO:0042608)
0.0 0.2 GO:0005521 lamin binding(GO:0005521)
0.0 0.2 GO:0004437 obsolete inositol or phosphatidylinositol phosphatase activity(GO:0004437)
0.0 0.1 GO:0031957 very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.0 0.1 GO:0042153 obsolete RPTP-like protein binding(GO:0042153)
0.0 0.1 GO:0004992 platelet activating factor receptor activity(GO:0004992)
0.0 0.1 GO:0050265 RNA uridylyltransferase activity(GO:0050265)
0.0 0.3 GO:0005035 death receptor activity(GO:0005035)
0.0 0.1 GO:0008443 phosphofructokinase activity(GO:0008443)
0.0 0.1 GO:0030284 estrogen receptor activity(GO:0030284)
0.0 0.1 GO:0042800 histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.0 0.1 GO:0050682 AF-2 domain binding(GO:0050682)
0.0 0.1 GO:0015216 adenine nucleotide transmembrane transporter activity(GO:0000295) purine nucleotide transmembrane transporter activity(GO:0015216)
0.0 0.0 GO:0004439 phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity(GO:0004439) phosphatidylinositol phosphate 5-phosphatase activity(GO:0034595)
0.0 0.0 GO:0004873 asialoglycoprotein receptor activity(GO:0004873)
0.0 0.1 GO:0004829 threonine-tRNA ligase activity(GO:0004829)
0.0 0.1 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.0 0.1 GO:0033829 O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.0 0.1 GO:0008526 phosphatidylinositol transporter activity(GO:0008526)
0.0 0.1 GO:0005138 interleukin-6 receptor binding(GO:0005138)
0.0 0.1 GO:0004813 alanine-tRNA ligase activity(GO:0004813)
0.0 0.1 GO:0030306 ADP-ribosylation factor binding(GO:0030306)
0.0 0.1 GO:0015347 sodium-independent organic anion transmembrane transporter activity(GO:0015347)
0.0 0.1 GO:0042285 UDP-xylosyltransferase activity(GO:0035252) xylosyltransferase activity(GO:0042285)
0.0 0.1 GO:0001085 RNA polymerase II transcription factor binding(GO:0001085)
0.0 0.1 GO:0017128 phospholipid scramblase activity(GO:0017128)
0.0 0.1 GO:0004032 alditol:NADP+ 1-oxidoreductase activity(GO:0004032)
0.0 0.1 GO:0004705 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.0 0.1 GO:0005314 high-affinity glutamate transmembrane transporter activity(GO:0005314)
0.0 0.2 GO:0030553 cGMP binding(GO:0030553)
0.0 0.2 GO:0008195 phosphatidate phosphatase activity(GO:0008195)
0.0 0.1 GO:0031014 troponin T binding(GO:0031014)
0.0 0.1 GO:0000339 RNA cap binding(GO:0000339)
0.0 0.1 GO:0050508 glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0050508)
0.0 0.1 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.0 0.2 GO:0017025 TBP-class protein binding(GO:0017025)
0.0 0.1 GO:0070326 very-low-density lipoprotein particle receptor binding(GO:0070326)
0.0 0.1 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.0 0.1 GO:0050543 icosatetraenoic acid binding(GO:0050543)
0.0 0.1 GO:0005042 netrin receptor activity(GO:0005042)
0.0 0.1 GO:0030172 troponin C binding(GO:0030172)
0.0 0.0 GO:0070324 thyroid hormone binding(GO:0070324)
0.0 0.1 GO:0004862 cAMP-dependent protein kinase inhibitor activity(GO:0004862)
0.0 0.1 GO:0017166 vinculin binding(GO:0017166)
0.0 0.0 GO:0004052 arachidonate 12-lipoxygenase activity(GO:0004052)
0.0 0.2 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0 0.0 GO:0030548 acetylcholine receptor regulator activity(GO:0030548) neurotransmitter receptor regulator activity(GO:0099602)
0.0 0.0 GO:0034186 apolipoprotein A-I binding(GO:0034186)
0.0 0.1 GO:0004706 JUN kinase kinase kinase activity(GO:0004706)
0.0 0.1 GO:0004305 ethanolamine kinase activity(GO:0004305)
0.0 0.1 GO:0015057 thrombin receptor activity(GO:0015057)
0.0 0.2 GO:0000155 phosphorelay sensor kinase activity(GO:0000155)
0.0 0.1 GO:0036002 pre-mRNA binding(GO:0036002)
0.0 0.1 GO:0015187 glycine transmembrane transporter activity(GO:0015187)
0.0 0.0 GO:0042808 obsolete neuronal Cdc2-like kinase binding(GO:0042808)
0.0 0.0 GO:0008109 N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109)
0.0 0.0 GO:0034711 inhibin binding(GO:0034711)
0.0 0.1 GO:0004616 phosphogluconate dehydrogenase (decarboxylating) activity(GO:0004616)
0.0 0.0 GO:0097493 extracellular matrix constituent conferring elasticity(GO:0030023) structural molecule activity conferring elasticity(GO:0097493)
0.0 0.1 GO:0001671 ATPase activator activity(GO:0001671)
0.0 0.0 GO:0030343 vitamin D3 25-hydroxylase activity(GO:0030343) vitamin D 25-hydroxylase activity(GO:0070643)
0.0 0.0 GO:0033300 dehydroascorbic acid transporter activity(GO:0033300)
0.0 0.1 GO:0016901 oxidoreductase activity, acting on the CH-OH group of donors, quinone or similar compound as acceptor(GO:0016901)
0.0 0.1 GO:0050780 dopamine receptor binding(GO:0050780)
0.0 0.2 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 0.0 GO:0015272 ATP-activated inward rectifier potassium channel activity(GO:0015272)
0.0 0.0 GO:0004937 alpha1-adrenergic receptor activity(GO:0004937)
0.0 0.0 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.0 0.1 GO:0016717 oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water(GO:0016717)
0.0 0.2 GO:0005227 calcium activated cation channel activity(GO:0005227)
0.0 0.1 GO:0004945 angiotensin receptor activity(GO:0001595) angiotensin type II receptor activity(GO:0004945)
0.0 0.1 GO:0005143 interleukin-12 receptor binding(GO:0005143)
0.0 0.1 GO:0035255 ionotropic glutamate receptor binding(GO:0035255)
0.0 0.1 GO:0031685 adenosine receptor binding(GO:0031685)
0.0 0.1 GO:0015252 hydrogen ion channel activity(GO:0015252)
0.0 0.1 GO:0004383 guanylate cyclase activity(GO:0004383)
0.0 0.1 GO:0034452 dynactin binding(GO:0034452)
0.0 0.1 GO:0004568 chitinase activity(GO:0004568)
0.0 0.1 GO:0016841 ammonia-lyase activity(GO:0016841)
0.0 0.0 GO:0004370 glycerol kinase activity(GO:0004370)
0.0 0.1 GO:0004983 neuropeptide Y receptor activity(GO:0004983)
0.0 0.1 GO:0005105 type 1 fibroblast growth factor receptor binding(GO:0005105)
0.0 0.1 GO:0034713 type I transforming growth factor beta receptor binding(GO:0034713)
0.0 0.0 GO:0051380 norepinephrine binding(GO:0051380)
0.0 0.0 GO:0004607 phosphatidylcholine-sterol O-acyltransferase activity(GO:0004607)
0.0 0.0 GO:0004307 ethanolaminephosphotransferase activity(GO:0004307)
0.0 0.1 GO:0033613 activating transcription factor binding(GO:0033613)
0.0 0.0 GO:0047184 1-acylglycerophosphocholine O-acyltransferase activity(GO:0047184)
0.0 0.0 GO:0005534 galactose binding(GO:0005534)
0.0 0.0 GO:0017162 aryl hydrocarbon receptor binding(GO:0017162)
0.0 0.0 GO:0005017 platelet-derived growth factor-activated receptor activity(GO:0005017)
0.0 0.0 GO:0016941 natriuretic peptide receptor activity(GO:0016941)
0.0 0.1 GO:0004185 serine-type carboxypeptidase activity(GO:0004185)
0.0 0.0 GO:0015379 potassium:chloride symporter activity(GO:0015379)
0.0 0.0 GO:0004500 dopamine beta-monooxygenase activity(GO:0004500)
0.0 0.0 GO:0004104 cholinesterase activity(GO:0004104)
0.0 0.0 GO:0005030 neurotrophin receptor activity(GO:0005030)
0.0 0.1 GO:0070290 N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.0 0.1 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.0 0.0 GO:0015016 [heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
0.0 0.0 GO:0004470 malic enzyme activity(GO:0004470)
0.0 0.3 GO:0017022 myosin binding(GO:0017022)
0.0 0.1 GO:0004022 alcohol dehydrogenase (NAD) activity(GO:0004022)
0.0 0.1 GO:0001640 adenylate cyclase inhibiting G-protein coupled glutamate receptor activity(GO:0001640) G-protein coupled glutamate receptor activity(GO:0098988)
0.0 0.1 GO:0043208 glycosphingolipid binding(GO:0043208)
0.0 0.0 GO:0004597 peptide-aspartate beta-dioxygenase activity(GO:0004597)
0.0 0.1 GO:0031435 mitogen-activated protein kinase kinase kinase binding(GO:0031435)
0.0 0.0 GO:0008192 RNA guanylyltransferase activity(GO:0008192)
0.0 0.0 GO:0004114 3',5'-cyclic-nucleotide phosphodiesterase activity(GO:0004114)
0.0 0.0 GO:0048495 Roundabout binding(GO:0048495)
0.0 0.0 GO:0004897 ciliary neurotrophic factor receptor activity(GO:0004897)
0.0 0.0 GO:0005047 signal recognition particle binding(GO:0005047)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.0 SIG PIP3 SIGNALING IN B LYMPHOCYTES Genes related to PIP3 signaling in B lymphocytes
0.0 0.0 ST INTERFERON GAMMA PATHWAY Interferon gamma pathway.
0.0 0.1 PID INTEGRIN A4B1 PATHWAY Alpha4 beta1 integrin signaling events
0.0 0.1 PID AVB3 INTEGRIN PATHWAY Integrins in angiogenesis
0.0 0.2 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0 0.0 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.0 0.0 PID RETINOIC ACID PATHWAY Retinoic acid receptors-mediated signaling
0.0 0.0 PID RANBP2 PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.0 0.4 PID HDAC CLASSII PATHWAY Signaling events mediated by HDAC Class II
0.0 0.2 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.0 0.2 SA CASPASE CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.0 0.3 PID SYNDECAN 4 PATHWAY Syndecan-4-mediated signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.0 REACTOME DOWNSTREAM SIGNALING OF ACTIVATED FGFR Genes involved in Downstream signaling of activated FGFR
0.0 0.0 REACTOME NCAM SIGNALING FOR NEURITE OUT GROWTH Genes involved in NCAM signaling for neurite out-growth
0.0 0.1 REACTOME REGULATION OF WATER BALANCE BY RENAL AQUAPORINS Genes involved in Regulation of Water Balance by Renal Aquaporins
0.0 0.5 REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.0 0.0 REACTOME ALPHA LINOLENIC ACID ALA METABOLISM Genes involved in alpha-linolenic acid (ALA) metabolism
0.0 0.0 REACTOME ACYL CHAIN REMODELLING OF PI Genes involved in Acyl chain remodelling of PI
0.0 0.4 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.0 0.2 REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
0.0 0.5 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.0 0.4 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.0 0.0 REACTOME PLATELET AGGREGATION PLUG FORMATION Genes involved in Platelet Aggregation (Plug Formation)
0.0 0.0 REACTOME SIGNALING BY CONSTITUTIVELY ACTIVE EGFR Genes involved in Signaling by constitutively active EGFR
0.0 0.2 REACTOME CRMPS IN SEMA3A SIGNALING Genes involved in CRMPs in Sema3A signaling
0.0 0.2 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.0 0.2 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.0 0.2 REACTOME ERKS ARE INACTIVATED Genes involved in ERKs are inactivated
0.0 0.1 REACTOME REGULATED PROTEOLYSIS OF P75NTR Genes involved in Regulated proteolysis of p75NTR
0.0 0.2 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.0 0.2 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.0 0.3 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.0 0.2 REACTOME G1 S SPECIFIC TRANSCRIPTION Genes involved in G1/S-Specific Transcription
0.0 0.2 REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT Genes involved in Organic cation/anion/zwitterion transport
0.0 0.1 REACTOME NRIF SIGNALS CELL DEATH FROM THE NUCLEUS Genes involved in NRIF signals cell death from the nucleus
0.0 0.1 REACTOME SIGNALING BY NOTCH3 Genes involved in Signaling by NOTCH3
0.0 0.1 REACTOME THROMBIN SIGNALLING THROUGH PROTEINASE ACTIVATED RECEPTORS PARS Genes involved in Thrombin signalling through proteinase activated receptors (PARs)
0.0 0.0 REACTOME APC C CDC20 MEDIATED DEGRADATION OF MITOTIC PROTEINS Genes involved in APC/C:Cdc20 mediated degradation of mitotic proteins
0.0 0.1 REACTOME GAP JUNCTION DEGRADATION Genes involved in Gap junction degradation
0.0 0.1 REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.0 0.1 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.0 0.1 REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.0 0.1 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.0 0.3 REACTOME NETRIN1 SIGNALING Genes involved in Netrin-1 signaling
0.0 0.0 REACTOME PI3K CASCADE Genes involved in PI3K Cascade