Project
ENCODE: H3K4me1 ChIP-Seq of primary human cells
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CREMA is a free online tool that recognizes most important transcription factors that change the chromatin state across different samples.

Results for NR1H2

Z-value: 0.73

Motif logo

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Transcription factors associated with NR1H2

Gene Symbol Gene ID Gene Info
NR1H2
ENSG00000131408.9 NR1H2

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE Gene Distance Association probability Pearson corr. coef. P-value Plot
NR1H2chr19_50881294_508814456780.4762180.674.7e-02Click!
NR1H2chr19_50834277_5083456314710.220966-0.599.5e-02Click!
NR1H2chr19_50834588_5083473917140.193850-0.452.3e-01Click!
NR1H2chr19_50880647_508809771210.914974-0.373.3e-01Click!
NR1H2chr19_50879366_508796392130.855874-0.304.2e-01Click!

Activity of the NR1H2 motif across conditions

Conditions sorted by the z-value of the NR1H2 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE) Target Score Top associated gene Gene Info Distance of CRE to TSS CRE/Gene association probability
chr14_69411531_69411698 0.37 ACTN1
 actinin, alpha 1
 2651
 0.33
chr12_52585063_52585443 0.34 KRT80
 keratin 80
 531
 0.69
chr6_44018695_44019099 0.31 RP5-1120P11.1
23492
 0.15
chr20_16536753_16536975 0.31 KIF16B
 kinesin family member 16B
 17214
 0.26
chr14_69421781_69422763 0.31 ACTN1
 actinin, alpha 1
 8007
 0.23
chr20_30284083_30284439 0.31 RP11-243J16.7
10242
 0.13
chr14_92970056_92970406 0.30 RIN3
 Ras and Rab interactor 3
 9887
 0.27
chr9_107673636_107673787 0.30 RP11-217B7.2
16123
 0.21
chr3_69813399_69813761 0.29 MITF
 microphthalmia-associated transcription factor
 618
 0.78
chr10_77189776_77190205 0.29 RP11-399K21.10
1356
 0.46
chr3_183016185_183016744 0.29 B3GNT5
 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 5
 33332
 0.16
chr1_183009603_183009956 0.28 LAMC1
 laminin, gamma 1 (formerly LAMB2)
 17184
 0.19
chr22_46402410_46402690 0.28 WNT7B
 wingless-type MMTV integration site family, member 7B
 29541
 0.1
chr3_67698671_67698976 0.28 SUCLG2
 succinate-CoA ligase, GDP-forming, beta subunit
 6208
 0.34
chr19_45428791_45429158 0.28 APOC1P1
 apolipoprotein C-I pseudogene 1
 1259
 0.23
chr17_75125652_75125803 0.28 SEC14L1
 SEC14-like 1 (S. cerevisiae)
 1772
 0.37
chr17_42173180_42173449 0.27 HDAC5
 histone deacetylase 5
 2759
 0.14
chr9_4086696_4086970 0.27 RP11-70J12.1
14949
 0.26
chr15_57902216_57902367 0.27 MYZAP
 myocardial zonula adherens protein
 10682
 0.2
chr1_165827591_165827945 0.27 UCK2
 uridine-cytidine kinase 2
 30709
 0.15
chr19_6233179_6233473 0.27 CTC-503J8.4
25842
 0.12
chr16_81572532_81572683 0.26 CMIP
 c-Maf inducing protein
 43653
 0.19
chr1_68218506_68218657 0.26 ENSG00000238778
 .
 19755
 0.2
chr13_80509662_80509813 0.26 SPRY2
 sprouty homolog 2 (Drosophila)
 404057
 0.01
chr3_127415621_127415936 0.26 ABTB1
 ankyrin repeat and BTB (POZ) domain containing 1
 22825
 0.15
chr19_49004091_49004498 0.26 LMTK3
 lemur tyrosine kinase 3
 10767
 0.1
chr3_193590030_193590181 0.26 ENSG00000243991
 .
 131595
 0.05
chr18_57223536_57223687 0.25 RP11-760L24.1
7330
 0.26
chr22_25979320_25979515 0.25 CTA-407F11.7
2068
 0.28
chr7_97982386_97982537 0.25 RP11-307C18.1
30296
 0.16
chr11_12307843_12308146 0.25 MICALCL
 MICAL C-terminal like
 453
 0.82
chr3_11178042_11178193 0.24 HRH1
 histamine receptor H1
 662
 0.81
chr12_81231723_81232151 0.24 ENSG00000207763
 .
 5529
 0.25
chr1_162680021_162680172 0.24 DDR2
 discoidin domain receptor tyrosine kinase 2
 56931
 0.11
chr2_54556871_54557022 0.24 C2orf73
 chromosome 2 open reading frame 73
 225
 0.96
chr3_149356541_149356692 0.24 WWTR1-IT1
 WWTR1 intronic transcript 1 (non-protein coding)
 11355
 0.17
chr12_13252440_13252619 0.24 GSG1
 germ cell associated 1
 3789
 0.25
chr8_144032439_144032590 0.23 CYP11B2
 cytochrome P450, family 11, subfamily B, polypeptide 2
 33255
 0.13
chr20_35110278_35110568 0.23 DLGAP4
 discs, large (Drosophila) homolog-associated protein 4
 20273
 0.17
chr5_138607548_138607819 0.23 MATR3
 matrin 3
 1758
 0.23
chr14_75080124_75080452 0.23 LTBP2
 latent transforming growth factor beta binding protein 2
 982
 0.57
chr17_47099426_47099577 0.23 RP11-501C14.6
8414
 0.1
chr6_123112103_123112308 0.23 SMPDL3A
 sphingomyelin phosphodiesterase, acid-like 3A
 1734
 0.38
chr15_41138763_41139692 0.23 SPINT1
 serine peptidase inhibitor, Kunitz type 1
 2354
 0.15
chr6_16367315_16367466 0.23 ENSG00000265642
 .
 61364
 0.14
chr1_235242449_235242943 0.23 ENSG00000207181
 .
 48556
 0.13
chr21_16594402_16594858 0.23 NRIP1
 nuclear receptor interacting protein 1
 157309
 0.04
chr12_58808774_58808925 0.22 RP11-362K2.2
 Protein LOC100506869
 129058
 0.06
chr9_125138658_125139005 0.22 PTGS1
 prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
 1230
 0.35
chr3_149738658_149738809 0.22 PFN2
 profilin 2
 1865
 0.34
chr4_184560268_184560547 0.22 ENSG00000252157
 .
 14422
 0.14
chr5_148352238_148352777 0.22 RP11-44B19.1
2604
 0.3
chr10_6763311_6763462 0.22 PRKCQ
 protein kinase C, theta
 141123
 0.05
chr4_7888432_7888664 0.22 AFAP1
 actin filament associated protein 1
 14508
 0.22
chr1_15610345_15610496 0.22 FHAD1
 forkhead-associated (FHA) phosphopeptide binding domain 1
 21838
 0.17
chr18_21296906_21297057 0.22 LAMA3
 laminin, alpha 3
 27333
 0.2
chr2_36565453_36565604 0.22 CRIM1
 cysteine rich transmembrane BMP regulator 1 (chordin-like)
 17541
 0.29
chr12_50452001_50452282 0.21 ASIC1
 acid-sensing (proton-gated) ion channel 1
 654
 0.59
chr21_38711029_38711180 0.21 AP001437.1
27130
 0.16
chr8_38858707_38858858 0.21 ADAM9
 ADAM metallopeptidase domain 9
 4277
 0.16
chr3_149254018_149254169 0.21 ENSG00000252581
 .
 10675
 0.2
chr8_146015607_146015758 0.21 RPL8
 ribosomal protein L8
 1856
 0.19
chr2_107618112_107618263 0.21 ST6GAL2
 ST6 beta-galactosamide alpha-2,6-sialyltranferase 2
 114623
 0.07
chr8_131687867_131688018 0.21 RP11-737F9.2
217089
 0.02
chr1_84719853_84720004 0.21 ENSG00000199959
 .
 23076
 0.21
chr17_26793910_26794378 0.21 SLC13A2
 solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 2
 6167
 0.11
chr8_129381988_129382255 0.21 ENSG00000201782
 .
 149371
 0.04
chr11_67781609_67782080 0.21 ALDH3B1
 aldehyde dehydrogenase 3 family, member B1
 4054
 0.13
chr2_147743058_147743209 0.21 ENSG00000238860
 .
 338406
 0.01
chr10_101946913_101947666 0.21 ERLIN1
 ER lipid raft associated 1
 802
 0.51
chr6_149491238_149491389 0.20 ENSG00000263481
 .
 6617
 0.24
chr2_216529775_216530114 0.20 ENSG00000212055
 .
 213698
 0.02
chr12_89328128_89328279 0.20 ENSG00000238302
 .
 347859
 0.01
chr1_16466515_16466919 0.20 RP11-276H7.2
14989
 0.11
chr19_56618769_56618997 0.20 ENSG00000223060
 .
 2098
 0.22
chr5_159107_159571 0.20 ENSG00000199540
 .
 15027
 0.14
chr8_142244739_142244890 0.20 SLC45A4
 solute carrier family 45, member 4
 4367
 0.18
chr2_28078222_28078373 0.20 RBKS
 ribokinase
 12269
 0.19
chr13_52157550_52158046 0.20 WDFY2
 WD repeat and FYVE domain containing 2
 846
 0.49
chr1_39583247_39583398 0.20 ENSG00000206654
 .
 3393
 0.22
chr11_10373135_10373286 0.20 AMPD3
 adenosine monophosphate deaminase 3
 33992
 0.13
chr5_154071675_154071826 0.20 ENSG00000221552
 .
 6414
 0.17
chr11_75269832_75269983 0.20 SERPINH1
 serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1)
 3194
 0.18
chr22_50356250_50357150 0.20 PIM3
 pim-3 oncogene
 2539
 0.27
chr2_234119413_234119564 0.20 ATG16L1
 autophagy related 16-like 1 (S. cerevisiae)
 791
 0.58
chr13_45013936_45014201 0.20 TSC22D1
 TSC22 domain family, member 1
 3087
 0.36
chr10_102124571_102124984 0.20 SCD
 stearoyl-CoA desaturase (delta-9-desaturase)
 17896
 0.13
chr6_37023589_37023822 0.20 COX6A1P2
 cytochrome c oxidase subunit VIa polypeptide 1 pseudogene 2
 11098
 0.2
chr1_24434630_24434891 0.20 MYOM3
 myomesin 3
 3905
 0.2
chr1_9731771_9732062 0.19 RP11-558F24.4
15697
 0.15
chr2_62881644_62881884 0.19 AC092155.4
7999
 0.23
chr15_57615898_57616159 0.19 TCF12
 transcription factor 12
 41375
 0.15
chr17_43577703_43578072 0.19 RP11-798G7.5
2739
 0.16
chr10_14117012_14117163 0.19 RP11-397C18.2
804
 0.73
chr2_227199398_227199549 0.19 ENSG00000263363
 .
 324036
 0.01
chr8_139856330_139856481 0.19 COL22A1
 collagen, type XXII, alpha 1
 64600
 0.15
chr7_40961790_40961941 0.19 AC005160.3
146708
 0.05
chr11_35058169_35058529 0.19 PDHX
 pyruvate dehydrogenase complex, component X
 59018
 0.11
chr10_128950431_128950582 0.19 FAM196A
 family with sequence similarity 196, member A
 24767
 0.25
chr6_108930285_108930625 0.19 FOXO3
 forkhead box O3
 47094
 0.18
chr10_96996414_96996565 0.19 RP11-310E22.4
5588
 0.25
chr1_167743848_167743999 0.19 MPZL1
 myelin protein zero-like 1
 9116
 0.23
chr10_80732581_80733347 0.19 ZMIZ1-AS1
 ZMIZ1 antisense RNA 1
 10813
 0.3
chr20_61469350_61469501 0.19 COL9A3
 collagen, type IX, alpha 3
 20262
 0.11
chr3_42077345_42077717 0.19 TRAK1
 trafficking protein, kinesin binding 1
 55031
 0.14
chr17_76677287_76677438 0.18 ENSG00000252391
 .
 15517
 0.19
chr22_41000981_41001132 0.18 MKL1
 megakaryoblastic leukemia (translocation) 1
 31633
 0.17
chr14_76287931_76288578 0.18 RP11-270M14.4
15300
 0.24
chr19_16175455_16175640 0.18 TPM4
 tropomyosin 4
 2284
 0.28
chr19_10728070_10728416 0.18 SLC44A2
 solute carrier family 44 (choline transporter), member 2
 7691
 0.11
chr20_19983328_19983514 0.18 NAA20
 N(alpha)-acetyltransferase 20, NatB catalytic subunit
 14339
 0.2
chr4_119260934_119261085 0.18 PRSS12
 protease, serine, 12 (neurotrypsin, motopsin)
 13149
 0.27
chr6_13302624_13303087 0.18 RP1-257A7.4
7037
 0.2
chr6_43094189_43094340 0.18 PTK7
 protein tyrosine kinase 7
 4065
 0.15
chr2_69261565_69261716 0.18 ANTXR1
 anthrax toxin receptor 1
 21111
 0.19
chr6_52217103_52217564 0.18 PAQR8
 progestin and adipoQ receptor family member VIII
 8886
 0.23
chr12_83113374_83113525 0.18 TMTC2
 transmembrane and tetratricopeptide repeat containing 2
 32669
 0.25
chr17_1391880_1392228 0.18 MYO1C
 myosin IC
 1700
 0.27
chr6_151990514_151990665 0.18 ESR1
 estrogen receptor 1
 21042
 0.22
chr6_7145383_7146135 0.18 RREB1
 ras responsive element binding protein 1
 6281
 0.22
chr10_114723539_114723817 0.18 RP11-57H14.2
12044
 0.22
chr7_92364918_92365200 0.18 ENSG00000206763
 .
 33931
 0.19
chr1_92317205_92317356 0.18 TGFBR3
 transforming growth factor, beta receptor III
 9870
 0.22
chr22_18373590_18373741 0.18 MICAL3
 microtubule associated monooxygenase, calponin and LIM domain containing 3
 4389
 0.26
chr11_122655696_122655847 0.17 CRTAM
 cytotoxic and regulatory T cell molecule
 53437
 0.13
chr4_185018477_185018810 0.17 STOX2
 storkhead box 2
 96165
 0.07
chr2_70823742_70823936 0.17 TGFA
 transforming growth factor, alpha
 42692
 0.15
chr20_13848549_13848700 0.17 NDUFAF5
 NADH dehydrogenase (ubiquinone) complex I, assembly factor 5
 82928
 0.08
chr8_142158040_142158331 0.17 DENND3
 DENN/MADD domain containing 3
 6883
 0.21
chr10_35595892_35596043 0.17 RP11-324I22.4
13959
 0.18
chr1_2321868_2322077 0.17 MORN1
 MORN repeat containing 1
 537
 0.55
chr1_178207539_178207690 0.17 RASAL2
 RAS protein activator like 2
 102992
 0.08
chr17_48502151_48502302 0.17 ACSF2
 acyl-CoA synthetase family member 2
 1293
 0.29
chr8_22604778_22604955 0.17 ENSG00000253125
 .
 150
 0.96
chr1_26021848_26022016 0.17 MAN1C1
 mannosidase, alpha, class 1C, member 1
 14161
 0.17
chr9_114737008_114737159 0.17 ENSG00000222356
 .
 21936
 0.17
chr19_3374038_3374830 0.17 NFIC
 nuclear factor I/C (CCAAT-binding transcription factor)
 7850
 0.19
chr3_66491690_66492240 0.17 LRIG1
 leucine-rich repeats and immunoglobulin-like domains 1
 59391
 0.15
chr20_47961516_47961667 0.17 ENSG00000212304
 .
 64371
 0.08
chr22_32865711_32865862 0.17 FBXO7
 F-box protein 7
 4877
 0.19
chr7_20259929_20260378 0.17 MACC1
 metastasis associated in colon cancer 1
 3126
 0.32
chr14_24866543_24866694 0.17 NYNRIN
 NYN domain and retroviral integrase containing
 1374
 0.25
chr9_120482996_120483203 0.17 ENSG00000251847
 .
 10650
 0.2
chr8_122369795_122369946 0.17 ENSG00000221644
 .
 170738
 0.03
chr2_237796357_237796508 0.17 ENSG00000202341
 .
 127516
 0.05
chr1_209381983_209382134 0.17 ENSG00000230937
 .
 223420
 0.02
chrX_148577496_148577647 0.17 IDS
 iduronate 2-sulfatase
 5687
 0.2
chr19_15425157_15425308 0.17 BRD4
 bromodomain containing 4
 17485
 0.16
chr18_3649805_3649956 0.17 RP11-874J12.4
3530
 0.24
chr1_17871900_17872051 0.17 ARHGEF10L
 Rho guanine nucleotide exchange factor (GEF) 10-like
 5645
 0.27
chr13_94847942_94848231 0.17 GPC6-AS1
 GPC6 antisense RNA 1
 7841
 0.32
chr8_29449879_29450030 0.17 RP4-676L2.1
239267
 0.02
chr4_140871909_140872439 0.17 MAML3
 mastermind-like 3 (Drosophila)
 60053
 0.14
chr2_43309506_43309703 0.16 ENSG00000207087
 .
 9028
 0.3
chr3_184561796_184561947 0.16 VPS8
 vacuolar protein sorting 8 homolog (S. cerevisiae)
 9408
 0.29
chr19_33686317_33686519 0.16 LRP3
 low density lipoprotein receptor-related protein 3
 928
 0.46
chr4_759415_759686 0.16 AC139887.4
688
 0.55
chr4_95481204_95481355 0.16 PDLIM5
 PDZ and LIM domain 5
 36403
 0.23
chr6_138084967_138085118 0.16 ENSG00000207300
 .
 20469
 0.21
chr19_13957292_13957443 0.16 ENSG00000207980
 .
 9894
 0.08
chr1_10447470_10447848 0.16 ENSG00000265945
 .
 2400
 0.2
chr12_107256430_107256581 0.16 RP11-144F15.1
 Uncharacterized protein
 87809
 0.07
chr2_56968245_56968396 0.16 ENSG00000238690
 .
 274979
 0.02
chr16_67124269_67124420 0.16 C16orf70
 chromosome 16 open reading frame 70
 19517
 0.1
chr2_47371206_47371357 0.16 C2orf61
 chromosome 2 open reading frame 61
 7153
 0.22
chr21_46826449_46826600 0.16 COL18A1
 collagen, type XVIII, alpha 1
 1472
 0.34
chr16_72882320_72882471 0.16 ENSG00000251868
 .
 26504
 0.17
chr1_233248528_233248728 0.16 PCNXL2
 pecanex-like 2 (Drosophila)
 47425
 0.19
chr11_514795_514946 0.16 RNH1
 ribonuclease/angiogenin inhibitor 1
 7570
 0.08
chr1_94188465_94188866 0.16 BCAR3
 breast cancer anti-estrogen resistance 3
 41280
 0.16
chr10_79637661_79637812 0.16 AL391421.1
 Uncharacterized protein; cDNA FLJ43696 fis, clone TBAES2007964
 11103
 0.18
chr3_127538975_127539236 0.16 MGLL
 monoglyceride lipase
 1881
 0.43
chr3_159505457_159505608 0.16 IQCJ-SCHIP1-AS1
 IQCJ-SCHIP1 readthrough antisense RNA 1
 19131
 0.15
chr16_23540221_23540372 0.16 GGA2
 golgi-associated, gamma adaptin ear containing, ARF binding protein 2
 6980
 0.14
chr1_61916105_61916328 0.16 NFIA
 nuclear factor I/A
 43872
 0.2
chr13_97951105_97951256 0.16 MBNL2
 muscleblind-like splicing regulator 2
 22722
 0.24
chr19_41727336_41727487 0.16 CTD-2195B23.3
545
 0.64
chr20_32653471_32653622 0.16 RP1-64K7.4
15409
 0.16
chr12_71040955_71041106 0.16 PTPRB
 protein tyrosine phosphatase, receptor type, B
 9810
 0.28
chr6_11092979_11093838 0.16 SMIM13
 small integral membrane protein 13
 858
 0.55
chr5_53750809_53750960 0.16 HSPB3
 heat shock 27kDa protein 3
 561
 0.84
chr15_68682519_68683065 0.16 ITGA11
 integrin, alpha 11
 41700
 0.18
chr12_89549700_89550075 0.15 ENSG00000238302
 .
 126175
 0.06
chr2_178119623_178120326 0.15 ENSG00000265396
 .
 764
 0.5
chr4_74587786_74587937 0.15 IL8
 interleukin 8
 18362
 0.22
chr3_142572644_142572856 0.15 PCOLCE2
 procollagen C-endopeptidase enhancer 2
 34991
 0.15
chr1_85786366_85786652 0.15 ENSG00000264380
 .
 36216
 0.12
chr3_12219225_12219376 0.15 TIMP4
 TIMP metallopeptidase inhibitor 4
 18449
 0.25
chr16_53133154_53133539 0.15 CHD9
 chromodomain helicase DNA binding protein 9
 274
 0.94
chr2_72162199_72162350 0.15 CYP26B1
 cytochrome P450, family 26, subfamily B, polypeptide 1
 207939
 0.03
chr17_38668560_38668716 0.15 TNS4
 tensin 4
 10789
 0.16
chr17_62174426_62174577 0.15 ERN1
 endoplasmic reticulum to nucleus signaling 1
 32984
 0.13
chr17_80343135_80343286 0.15 UTS2R
 urotensin 2 receptor
 11057
 0.09
chr1_94719949_94720119 0.15 ARHGAP29
 Rho GTPase activating protein 29
 16845
 0.24
chr10_30101231_30101626 0.15 SVIL
 supervillin
 76695
 0.11
chr17_1621771_1622017 0.15 WDR81
 WD repeat domain 81
 1999
 0.18
chr17_32999536_32999687 0.15 TMEM132E
 transmembrane protein 132E
 91843
 0.08
chr5_139641185_139641634 0.15 PFDN1
 prefoldin subunit 1
 41259
 0.1
chr15_38691031_38691182 0.15 FAM98B
 family with sequence similarity 98, member B
 55222
 0.14
chr4_102160089_102160359 0.15 ENSG00000221265
 .
 91347
 0.09

Histogram of CRE-TSS distances for CREs targeted by :

Histogram of

Rank distribution of CRE target scores:

Histogram of target CRE score.

Distribution of target CREs across different genomic regions:

Weighted Piechart of Weighted Piechart of Weighted Piechart of

Network of associatons between targets according to the STRING database.

StringDB image

First level regulatory network of NR1H2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0070427 nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070427)
0.0 0.1 GO:0071637 monocyte chemotactic protein-1 production(GO:0071605) regulation of monocyte chemotactic protein-1 production(GO:0071637)
0.0 0.1 GO:0018344 protein geranylgeranylation(GO:0018344)
0.0 0.1 GO:0009169 purine nucleoside monophosphate catabolic process(GO:0009128) ribonucleoside monophosphate catabolic process(GO:0009158) purine ribonucleoside monophosphate catabolic process(GO:0009169)
0.0 0.3 GO:0009629 response to gravity(GO:0009629)
0.0 0.1 GO:0032488 Cdc42 protein signal transduction(GO:0032488)
0.0 0.1 GO:1902745 positive regulation of lamellipodium assembly(GO:0010592) positive regulation of lamellipodium organization(GO:1902745)
0.0 0.1 GO:0006104 succinyl-CoA metabolic process(GO:0006104)
0.0 0.0 GO:0051771 negative regulation of nitric-oxide synthase biosynthetic process(GO:0051771)
0.0 0.1 GO:0061364 apoptotic process involved in luteolysis(GO:0061364)
0.0 0.2 GO:0007185 transmembrane receptor protein tyrosine phosphatase signaling pathway(GO:0007185)
0.0 0.1 GO:0071731 response to nitric oxide(GO:0071731)
0.0 0.1 GO:0051176 positive regulation of sulfur metabolic process(GO:0051176)
0.0 0.1 GO:0044415 evasion or tolerance of host defenses by virus(GO:0019049) avoidance of host defenses(GO:0044413) evasion or tolerance of host defenses(GO:0044415) avoidance of defenses of other organism involved in symbiotic interaction(GO:0051832) evasion or tolerance of defenses of other organism involved in symbiotic interaction(GO:0051834)
0.0 0.1 GO:0031536 positive regulation of exit from mitosis(GO:0031536)
0.0 0.1 GO:0010040 response to iron(II) ion(GO:0010040)
0.0 0.0 GO:0032261 purine nucleotide salvage(GO:0032261)
0.0 0.0 GO:0045541 negative regulation of cholesterol biosynthetic process(GO:0045541) negative regulation of cholesterol metabolic process(GO:0090206)
0.0 0.1 GO:0048170 positive regulation of long-term neuronal synaptic plasticity(GO:0048170)
0.0 0.1 GO:0018101 protein citrullination(GO:0018101)
0.0 0.1 GO:0001547 antral ovarian follicle growth(GO:0001547)
0.0 0.1 GO:0010700 negative regulation of norepinephrine secretion(GO:0010700)
0.0 0.1 GO:0002634 regulation of germinal center formation(GO:0002634)
0.0 0.1 GO:0008354 germ cell migration(GO:0008354)
0.0 0.0 GO:0048319 axial mesoderm morphogenesis(GO:0048319)
0.0 0.0 GO:0060267 positive regulation of respiratory burst(GO:0060267)
0.0 0.0 GO:0032467 positive regulation of cytokinesis(GO:0032467)
0.0 0.1 GO:0007028 cytoplasm organization(GO:0007028)
0.0 0.2 GO:0031581 hemidesmosome assembly(GO:0031581)
0.0 0.1 GO:0007095 mitotic G2 DNA damage checkpoint(GO:0007095)
0.0 0.1 GO:0016266 O-glycan processing(GO:0016266)
0.0 0.2 GO:0001829 trophectodermal cell differentiation(GO:0001829)
0.0 0.0 GO:2000114 regulation of establishment of cell polarity(GO:2000114)
0.0 0.1 GO:0070934 CRD-mediated mRNA stabilization(GO:0070934)
0.0 0.0 GO:0055089 fatty acid homeostasis(GO:0055089)
0.0 0.1 GO:0009649 entrainment of circadian clock(GO:0009649)
0.0 0.1 GO:0050665 hydrogen peroxide biosynthetic process(GO:0050665)
0.0 0.1 GO:0035414 negative regulation of catenin import into nucleus(GO:0035414)
0.0 0.0 GO:0045989 positive regulation of striated muscle contraction(GO:0045989)
0.0 0.1 GO:0060666 dichotomous subdivision of terminal units involved in salivary gland branching(GO:0060666)
0.0 0.0 GO:0045112 integrin biosynthetic process(GO:0045112)
0.0 0.0 GO:0001996 positive regulation of heart rate by epinephrine-norepinephrine(GO:0001996)
0.0 0.1 GO:0051549 regulation of keratinocyte migration(GO:0051547) positive regulation of keratinocyte migration(GO:0051549)
0.0 0.0 GO:0060129 thyroid-stimulating hormone-secreting cell differentiation(GO:0060129)
0.0 0.1 GO:0046504 ether lipid biosynthetic process(GO:0008611) glycerol ether biosynthetic process(GO:0046504) ether biosynthetic process(GO:1901503)
0.0 0.0 GO:0010591 regulation of lamellipodium assembly(GO:0010591)
0.0 0.0 GO:0045077 negative regulation of interferon-gamma biosynthetic process(GO:0045077)
0.0 0.0 GO:0071436 sodium ion export(GO:0071436)
0.0 0.1 GO:0010510 acetyl-CoA biosynthetic process from pyruvate(GO:0006086) regulation of acetyl-CoA biosynthetic process from pyruvate(GO:0010510) regulation of acyl-CoA biosynthetic process(GO:0050812)
0.0 0.0 GO:0035581 sequestering of extracellular ligand from receptor(GO:0035581) sequestering of TGFbeta in extracellular matrix(GO:0035583) protein localization to extracellular region(GO:0071692) maintenance of protein location in extracellular region(GO:0071694) extracellular regulation of signal transduction(GO:1900115) extracellular negative regulation of signal transduction(GO:1900116)
0.0 0.0 GO:0003077 obsolete negative regulation of diuresis(GO:0003077)
0.0 0.1 GO:0006685 sphingomyelin catabolic process(GO:0006685)
0.0 0.0 GO:0032641 lymphotoxin A production(GO:0032641) lymphotoxin A biosynthetic process(GO:0042109)
0.0 0.0 GO:1903332 regulation of protein folding(GO:1903332)
0.0 0.0 GO:0030011 maintenance of cell polarity(GO:0030011)
0.0 0.0 GO:0014819 regulation of skeletal muscle contraction(GO:0014819)
0.0 0.0 GO:0051014 actin filament severing(GO:0051014)
0.0 0.0 GO:0031665 negative regulation of lipopolysaccharide-mediated signaling pathway(GO:0031665)
0.0 0.0 GO:0043619 regulation of transcription from RNA polymerase II promoter in response to oxidative stress(GO:0043619)
0.0 0.1 GO:0007020 microtubule nucleation(GO:0007020)
0.0 0.1 GO:0060710 chorio-allantoic fusion(GO:0060710)
0.0 0.0 GO:0006701 progesterone biosynthetic process(GO:0006701)
0.0 0.0 GO:0031340 positive regulation of vesicle fusion(GO:0031340)
0.0 0.0 GO:0018243 protein O-linked glycosylation via serine(GO:0018242) protein O-linked glycosylation via threonine(GO:0018243)
0.0 0.1 GO:0006000 fructose metabolic process(GO:0006000)
0.0 0.0 GO:0035511 oxidative DNA demethylation(GO:0035511)
0.0 0.1 GO:0008655 pyrimidine-containing compound salvage(GO:0008655) pyrimidine nucleoside salvage(GO:0043097)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 GO:0031143 pseudopodium(GO:0031143)
0.0 0.1 GO:0071664 catenin-TCF7L2 complex(GO:0071664)
0.0 0.1 GO:0030056 hemidesmosome(GO:0030056)
0.0 0.1 GO:0043083 synaptic cleft(GO:0043083)
0.0 0.1 GO:0043260 laminin-11 complex(GO:0043260)
0.0 0.1 GO:0034045 pre-autophagosomal structure membrane(GO:0034045)
0.0 0.1 GO:0005862 muscle thin filament tropomyosin(GO:0005862)
0.0 0.1 GO:0033268 node of Ranvier(GO:0033268)
0.0 0.1 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
0.0 0.1 GO:0070937 CRD-mediated mRNA stability complex(GO:0070937)
0.0 0.0 GO:0034673 inhibin-betaglycan-ActRII complex(GO:0034673)
0.0 0.0 GO:0005899 insulin receptor complex(GO:0005899)
0.0 0.1 GO:0070776 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.0 0.0 GO:0005594 collagen type IX trimer(GO:0005594)
0.0 0.1 GO:0030061 mitochondrial crista(GO:0030061)
0.0 0.1 GO:0016461 unconventional myosin complex(GO:0016461)
0.0 0.0 GO:0005588 collagen type V trimer(GO:0005588)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.3 GO:0004969 histamine receptor activity(GO:0004969)
0.0 0.1 GO:0008109 N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109)
0.0 0.1 GO:0034186 apolipoprotein A-I binding(GO:0034186)
0.0 0.1 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.0 0.1 GO:0005010 insulin-like growth factor-activated receptor activity(GO:0005010)
0.0 0.1 GO:0008184 glycogen phosphorylase activity(GO:0008184)
0.0 0.1 GO:0047623 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.0 0.0 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.0 0.1 GO:0050508 glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0050508)
0.0 0.1 GO:0004774 succinate-CoA ligase activity(GO:0004774)
0.0 0.1 GO:0043559 insulin binding(GO:0043559)
0.0 0.2 GO:0017166 vinculin binding(GO:0017166)
0.0 0.1 GO:0070576 vitamin D 24-hydroxylase activity(GO:0070576)
0.0 0.2 GO:0051019 mitogen-activated protein kinase binding(GO:0051019)
0.0 0.1 GO:0004185 serine-type carboxypeptidase activity(GO:0004185)
0.0 0.1 GO:0042577 lipid phosphatase activity(GO:0042577)
0.0 0.1 GO:0004128 cytochrome-b5 reductase activity, acting on NAD(P)H(GO:0004128)
0.0 0.1 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.0 0.1 GO:0042285 UDP-xylosyltransferase activity(GO:0035252) xylosyltransferase activity(GO:0042285)
0.0 0.1 GO:0004668 protein-arginine deiminase activity(GO:0004668)
0.0 0.0 GO:0016215 stearoyl-CoA 9-desaturase activity(GO:0004768) acyl-CoA desaturase activity(GO:0016215)
0.0 0.1 GO:0004661 protein geranylgeranyltransferase activity(GO:0004661)
0.0 0.0 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.0 0.1 GO:0005021 vascular endothelial growth factor-activated receptor activity(GO:0005021)
0.0 0.0 GO:0042808 obsolete neuronal Cdc2-like kinase binding(GO:0042808)
0.0 0.1 GO:0005161 platelet-derived growth factor receptor binding(GO:0005161)
0.0 0.1 GO:0001875 lipopolysaccharide receptor activity(GO:0001875)
0.0 0.0 GO:0015016 [heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
0.0 0.1 GO:0004982 N-formyl peptide receptor activity(GO:0004982)
0.0 0.0 GO:0019136 deoxynucleoside kinase activity(GO:0019136)
0.0 0.1 GO:0090482 vitamin transmembrane transporter activity(GO:0090482)
0.0 0.0 GO:0042805 actinin binding(GO:0042805)
0.0 0.0 GO:0048027 mRNA 5'-UTR binding(GO:0048027)
0.0 0.0 GO:1901567 icosanoid binding(GO:0050542) fatty acid derivative binding(GO:1901567)
0.0 0.0 GO:0004095 carnitine O-palmitoyltransferase activity(GO:0004095) O-palmitoyltransferase activity(GO:0016416)
0.0 0.0 GO:0004596 peptide alpha-N-acetyltransferase activity(GO:0004596)
0.0 0.0 GO:0034056 estrogen response element binding(GO:0034056)
0.0 0.1 GO:0008113 peptide-methionine (S)-S-oxide reductase activity(GO:0008113)
0.0 0.0 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.0 0.0 GO:0004849 uridine kinase activity(GO:0004849)
0.0 0.0 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.0 0.1 GO:0008294 calcium- and calmodulin-responsive adenylate cyclase activity(GO:0008294)
0.0 0.0 GO:0016454 serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
0.0 0.0 GO:0042978 ornithine decarboxylase activator activity(GO:0042978)
0.0 0.0 GO:0016531 copper chaperone activity(GO:0016531)
0.0 0.0 GO:0003953 NAD+ nucleosidase activity(GO:0003953)
0.0 0.1 GO:0008046 axon guidance receptor activity(GO:0008046)
0.0 0.0 GO:0035514 DNA demethylase activity(GO:0035514) DNA-N1-methyladenine dioxygenase activity(GO:0043734)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.0 PID TRAIL PATHWAY TRAIL signaling pathway
0.0 0.2 PID IL5 PATHWAY IL5-mediated signaling events
0.0 0.1 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.0 0.4 PID P38 ALPHA BETA DOWNSTREAM PATHWAY Signaling mediated by p38-alpha and p38-beta

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.0 REACTOME G ALPHA Z SIGNALLING EVENTS Genes involved in G alpha (z) signalling events
0.0 0.0 REACTOME DESTABILIZATION OF MRNA BY BRF1 Genes involved in Destabilization of mRNA by Butyrate Response Factor 1 (BRF1)
0.0 0.1 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.0 0.0 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.0 0.1 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.0 0.1 REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters