Project
ENCODE: H3K4me1 ChIP-Seq of primary human cells
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CREMA is a free online tool that recognizes most important transcription factors that change the chromatin state across different samples.

Results for NR1H4

Z-value: 2.14

Motif logo

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Transcription factors associated with NR1H4

Gene Symbol Gene ID Gene Info
ENSG00000012504.9 NR1H4

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE Gene Distance Association probability Pearson corr. coef. P-value Plot
NR1H4chr12_100878368_100878519107100.2395670.481.9e-01Click!
NR1H4chr12_100878057_100878208103990.2403770.166.8e-01Click!
NR1H4chr12_100841558_100841709258530.185459-0.088.3e-01Click!

Activity of the NR1H4 motif across conditions

Conditions sorted by the z-value of the NR1H4 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE) Target Score Top associated gene Gene Info Distance of CRE to TSS CRE/Gene association probability
chr20_56039749_56039992 4.45 CTCFL
CCCTC-binding factor (zinc finger protein)-like
59443
0.1
chr17_72787457_72787723 1.31 TMEM104
transmembrane protein 104
14931
0.1
chr9_92083234_92083501 1.24 SEMA4D
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D
11438
0.23
chr19_5952060_5952229 1.11 RANBP3
RAN binding protein 3
25946
0.08
chr7_156715297_156715479 1.00 NOM1
nucleolar protein with MIF4G domain 1
27029
0.15
chr10_30995761_30995912 0.99 SVILP1
supervillin pseudogene 1
10986
0.26
chr15_89200326_89200502 0.93 ISG20
interferon stimulated exonuclease gene 20kDa
18230
0.16
chr19_16677483_16677695 0.92 CTD-3222D19.10

1227
0.26
chr19_42382114_42382373 0.92 CD79A
CD79a molecule, immunoglobulin-associated alpha
868
0.44
chr14_91855068_91855898 0.91 CCDC88C
coiled-coil domain containing 88C
28207
0.19
chr3_16326802_16326964 0.91 OXNAD1
oxidoreductase NAD-binding domain containing 1
16135
0.16
chr1_28318555_28318747 0.90 RP11-460I13.2

31947
0.1
chr7_100147991_100148484 0.89 AGFG2
ArfGAP with FG repeats 2
5053
0.1
chr14_21492164_21492434 0.89 NDRG2
NDRG family member 2
44
0.94
chr4_100739674_100739989 0.89 DAPP1
dual adaptor of phosphotyrosine and 3-phosphoinositides
1828
0.43
chr4_2815730_2815905 0.88 SH3BP2
SH3-domain binding protein 2
1786
0.37
chr9_95791042_95791245 0.86 FGD3
FYVE, RhoGEF and PH domain containing 3
13801
0.18
chr22_24039705_24040048 0.86 RGL4
ral guanine nucleotide dissociation stimulator-like 4
1205
0.35
chr6_110796846_110797132 0.83 SLC22A16
solute carrier family 22 (organic cation/carnitine transporter), member 16
610
0.69
chr14_96830281_96830470 0.80 ATG2B
autophagy related 2B
168
0.79
chr3_32376993_32377254 0.79 CMTM7
CKLF-like MARVEL transmembrane domain containing 7
56040
0.12
chr11_1876820_1877006 0.78 LSP1
lymphocyte-specific protein 1
2713
0.14
chr16_21658961_21659187 0.78 IGSF6
immunoglobulin superfamily, member 6
4853
0.13
chr17_25622305_25622549 0.78 WSB1
WD repeat and SOCS box containing 1
1055
0.47
chr2_97627578_97627763 0.78 ENSG00000252845
.
5118
0.16
chr19_55009048_55009414 0.77 LAIR2
leukocyte-associated immunoglobulin-like receptor 2
131
0.93
chr11_60793314_60793556 0.77 CD6
CD6 molecule
17429
0.14
chr11_67173408_67173659 0.77 TBC1D10C
TBC1 domain family, member 10C
1873
0.13
chr17_72674371_72674771 0.76 CTD-2006K23.2

832
0.49
chr1_20015023_20015174 0.75 HTR6
5-hydroxytryptamine (serotonin) receptor 6, G protein-coupled
23318
0.16
chr16_30461939_30462216 0.75 ENSG00000202476
.
3341
0.08
chr10_73514245_73514396 0.74 C10orf54
chromosome 10 open reading frame 54
3067
0.26
chr7_148325963_148326351 0.72 C7orf33
chromosome 7 open reading frame 33
38500
0.16
chr2_68979555_68979777 0.71 ARHGAP25
Rho GTPase activating protein 25
17652
0.23
chr7_50309220_50309371 0.69 IKZF1
IKAROS family zinc finger 1 (Ikaros)
35029
0.21
chr9_117752150_117752475 0.69 TNFSF8
tumor necrosis factor (ligand) superfamily, member 8
59615
0.13
chr11_73688013_73688255 0.68 UCP2
uncoupling protein 2 (mitochondrial, proton carrier)
83
0.96
chr1_111738933_111739395 0.68 DENND2D
DENN/MADD domain containing 2D
4147
0.14
chr3_111032298_111032588 0.67 CD96
CD96 molecule
20877
0.27
chrX_133961365_133961516 0.67 FAM122C
family with sequence similarity 122C
20173
0.16
chr14_106691102_106691449 0.66 IGHV3-21
immunoglobulin heavy variable 3-21
928
0.23
chr8_21436069_21436236 0.66 ENSG00000266630
.
28643
0.23
chr3_195516005_195516156 0.65 MUC4
mucin 4, cell surface associated
22648
0.17
chr3_16880178_16880359 0.65 PLCL2
phospholipase C-like 2
46184
0.18
chr11_67042731_67042882 0.65 ADRBK1
adrenergic, beta, receptor kinase 1
8854
0.11
chr7_150725797_150726152 0.65 ABCB8
ATP-binding cassette, sub-family B (MDR/TAP), member 8
420
0.58
chr14_22978569_22978851 0.64 TRAJ15
T cell receptor alpha joining 15
19870
0.09
chr16_9229875_9230060 0.64 RP11-473I1.10

28869
0.14
chr1_23858474_23858728 0.63 E2F2
E2F transcription factor 2
889
0.58
chr2_29236792_29237319 0.63 FAM179A
family with sequence similarity 179, member A
4072
0.19
chr1_114483922_114484073 0.63 HIPK1
homeodomain interacting protein kinase 1
9770
0.13
chr17_15490936_15491230 0.63 CDRT1
CMT1A duplicated region transcript 1
5639
0.14
chr1_147118412_147118650 0.63 ACP6
acid phosphatase 6, lysophosphatidic
12585
0.22
chr18_2968689_2969110 0.62 RP11-737O24.1

1883
0.28
chr4_39974923_39975074 0.61 PDS5A
PDS5, regulator of cohesion maintenance, homolog A (S. cerevisiae)
4578
0.24
chr14_75173644_75173816 0.61 ENSG00000222604
.
4924
0.14
chr10_112483545_112483823 0.61 ENSG00000252036
.
32530
0.14
chr1_9789105_9789546 0.60 PIK3CD
phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta
11198
0.17
chr1_226917633_226918259 0.60 ITPKB
inositol-trisphosphate 3-kinase B
7213
0.24
chr5_98362452_98362659 0.60 ENSG00000200351
.
90104
0.09
chr17_46514062_46514320 0.60 SKAP1
src kinase associated phosphoprotein 1
6610
0.15
chr9_92054735_92055023 0.60 SEMA4D
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D
3481
0.31
chr2_233973156_233973633 0.59 INPP5D
inositol polyphosphate-5-phosphatase, 145kDa
48205
0.13
chr5_156704413_156704690 0.59 CYFIP2
cytoplasmic FMR1 interacting protein 2
7821
0.15
chr9_515997_516400 0.59 ENSG00000264949
.
8645
0.14
chr6_24867385_24867536 0.59 FAM65B
family with sequence similarity 65, member B
10081
0.19
chr19_54880893_54881262 0.58 LAIR1
leukocyte-associated immunoglobulin-like receptor 1
981
0.39
chr11_7552437_7552588 0.57 PPFIBP2
PTPRF interacting protein, binding protein 2 (liprin beta 2)
6996
0.19
chr17_78682799_78682950 0.57 RP11-28G8.1

96558
0.07
chr8_134074351_134074605 0.57 SLA
Src-like-adaptor
1875
0.43
chr10_112033900_112034112 0.56 SMNDC1
survival motor neuron domain containing 1
30449
0.18
chr8_27242274_27242551 0.56 PTK2B
protein tyrosine kinase 2 beta
4244
0.27
chr16_11325836_11325987 0.56 RMI2
RecQ mediated genome instability 2
17595
0.1
chr2_143910130_143910379 0.56 RP11-190J23.1

19487
0.22
chr1_65357847_65358013 0.55 JAK1
Janus kinase 1
74257
0.11
chr17_66234189_66234340 0.55 AMZ2
archaelysin family metallopeptidase 2
9451
0.16
chr1_151131578_151131836 0.55 SCNM1
sodium channel modifier 1
2567
0.12
chr1_206734639_206734815 0.54 RASSF5
Ras association (RalGDS/AF-6) domain family member 5
4234
0.2
chr11_35353519_35353703 0.54 SLC1A2
solute carrier family 1 (glial high affinity glutamate transporter), member 2
30536
0.17
chrX_70279615_70279837 0.54 SNX12
sorting nexin 12
8527
0.13
chr14_107130545_107130696 0.54 IGHV3-66
immunoglobulin heavy variable 3-66
940
0.18
chr8_134538342_134538795 0.54 ST3GAL1
ST3 beta-galactoside alpha-2,3-sialyltransferase 1
26942
0.25
chr1_5483788_5483939 0.54 ENSG00000264341
.
140268
0.05
chr5_118618812_118619065 0.54 TNFAIP8
tumor necrosis factor, alpha-induced protein 8
14489
0.18
chr13_41165280_41165660 0.54 AL133318.1
Uncharacterized protein
54147
0.14
chr9_135997202_135997382 0.54 RALGDS
ral guanine nucleotide dissociation stimulator
729
0.58
chr17_38635847_38636232 0.53 TNS4
tensin 4
1139
0.44
chr3_124720888_124721039 0.53 HEG1
heart development protein with EGF-like domains 1
99
0.97
chr13_74277884_74278165 0.53 KLF12
Kruppel-like factor 12
291162
0.01
chr2_106380015_106380293 0.53 NCK2
NCK adaptor protein 2
17966
0.27
chr9_127957633_127957872 0.53 RABEPK
Rab9 effector protein with kelch motifs
5069
0.17
chr5_39075421_39075578 0.53 RICTOR
RPTOR independent companion of MTOR, complex 2
989
0.64
chr19_42144649_42144840 0.53 CEACAM4
carcinoembryonic antigen-related cell adhesion molecule 4
11302
0.14
chr9_124218171_124218322 0.53 ENSG00000240299
.
38551
0.14
chr19_2561367_2561584 0.53 CTC-265F19.2

50385
0.09
chr15_64388627_64388778 0.53 SNX1
sorting nexin 1
477
0.73
chr16_30395134_30395286 0.53 SEPT1
septin 1
1039
0.28
chr7_8016148_8016299 0.52 AC006042.7

6689
0.19
chr2_222330421_222330740 0.52 EPHA4
EPH receptor A4
36700
0.2
chr2_87824602_87824793 0.52 RP11-1399P15.1

47144
0.18
chr5_172115051_172115202 0.52 CTB-79E8.2

9597
0.16
chr6_109771688_109771889 0.52 MICAL1
microtubule associated monooxygenase, calponin and LIM domain containing 1
802
0.48
chr16_89794033_89794184 0.52 ZNF276
zinc finger protein 276
6156
0.1
chr4_109028258_109028423 0.52 LEF1
lymphoid enhancer-binding factor 1
59117
0.12
chr1_111984468_111984619 0.52 RP11-552M11.4

557
0.57
chr22_40324230_40324381 0.52 GRAP2
GRB2-related adaptor protein 2
1664
0.35
chr20_39510251_39510483 0.51 ENSG00000238908
.
27498
0.24
chr7_129424752_129424903 0.51 ENSG00000207691
.
9973
0.15
chr22_50837864_50838126 0.51 ENSG00000238604
.
746
0.51
chr1_67427377_67427614 0.51 MIER1
mesoderm induction early response 1, transcriptional regulator
31569
0.16
chr21_46953100_46953305 0.51 SLC19A1
solute carrier family 19 (folate transporter), member 1
1327
0.48
chr11_121331388_121331838 0.50 RP11-730K11.1

7891
0.25
chr1_154926882_154927088 0.50 PBXIP1
pre-B-cell leukemia homeobox interacting protein 1
1595
0.18
chr16_88755979_88756211 0.50 SNAI3
snail family zinc finger 3
3194
0.1
chr8_37553639_37554052 0.49 ZNF703
zinc finger protein 703
576
0.66
chr19_42081963_42082129 0.49 CEACAM21
carcinoembryonic antigen-related cell adhesion molecule 21
541
0.74
chr16_28219632_28219882 0.49 XPO6
exportin 6
3040
0.24
chr12_133410838_133411057 0.49 ENSG00000252079
.
1139
0.41
chr14_71112294_71112797 0.49 TTC9
tetratricopeptide repeat domain 9
4041
0.25
chr12_116538771_116538922 0.48 ENSG00000200665
.
18471
0.21
chr19_42050710_42050898 0.48 CEACAM21
carcinoembryonic antigen-related cell adhesion molecule 21
5082
0.19
chr6_36172309_36172647 0.48 BRPF3
bromodomain and PHD finger containing, 3
287
0.89
chr17_38079214_38079389 0.48 ORMDL3
ORM1-like 3 (S. cerevisiae)
1155
0.35
chr2_54794169_54794386 0.48 SPTBN1
spectrin, beta, non-erythrocytic 1
8746
0.19
chr12_123010667_123010875 0.48 RSRC2
arginine/serine-rich coiled-coil 2
716
0.5
chr16_30490311_30490462 0.48 RP11-297C4.3

2281
0.1
chr19_48827788_48827939 0.48 EMP3
epithelial membrane protein 3
719
0.53
chr16_49474926_49475274 0.48 C16orf78
chromosome 16 open reading frame 78
67366
0.13
chr13_22637652_22638073 0.48 ENSG00000244197
.
273186
0.02
chr9_20228261_20228412 0.48 ENSG00000221744
.
66666
0.13
chr9_135905332_135905511 0.48 GTF3C5
general transcription factor IIIC, polypeptide 5, 63kDa
655
0.62
chr2_112183128_112183279 0.48 ENSG00000266139
.
104535
0.08
chr9_92056751_92057221 0.48 SEMA4D
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D
5588
0.27
chr2_135425836_135426057 0.47 TMEM163
transmembrane protein 163
50624
0.17
chr2_204798430_204798581 0.47 ICOS
inducible T-cell co-stimulator
2966
0.36
chr1_226900136_226900391 0.47 ITPKB
inositol-trisphosphate 3-kinase B
24896
0.18
chr2_234318127_234318385 0.47 DGKD
diacylglycerol kinase, delta 130kDa
21456
0.15
chr1_154757692_154757865 0.47 KCNN3
potassium intermediate/small conductance calcium-activated channel, subfamily N, member 3
74541
0.07
chr6_76316591_76316805 0.47 SENP6
SUMO1/sentrin specific peptidase 6
4935
0.19
chr19_18200434_18200728 0.47 IL12RB1
interleukin 12 receptor, beta 1
2768
0.19
chr4_38607318_38607597 0.47 RP11-617D20.1

18739
0.21
chr12_40589336_40589575 0.47 LRRK2
leucine-rich repeat kinase 2
1091
0.6
chr12_111608513_111608664 0.47 CUX2
cut-like homeobox 2
71338
0.1
chr10_72083599_72083820 0.47 NPFFR1
neuropeptide FF receptor 1
40277
0.14
chr9_126138722_126138873 0.47 CRB2
crumbs homolog 2 (Drosophila)
7629
0.23
chr1_23945435_23945729 0.47 MDS2
myelodysplastic syndrome 2 translocation associated
8242
0.19
chr19_9968157_9968686 0.47 OLFM2
olfactomedin 2
423
0.71
chr12_111166521_111166691 0.47 PPP1CC
protein phosphatase 1, catalytic subunit, gamma isozyme
4087
0.23
chr17_75879008_75879611 0.46 FLJ45079

650
0.77
chr14_60621220_60621381 0.46 DHRS7
dehydrogenase/reductase (SDR family) member 7
1408
0.46
chr10_114711627_114712035 0.46 RP11-57H14.2

197
0.91
chr2_198169561_198169772 0.46 ANKRD44-IT1
ANKRD44 intronic transcript 1 (non-protein coding)
2423
0.25
chr8_19329786_19330179 0.46 CSGALNACT1
chondroitin sulfate N-acetylgalactosaminyltransferase 1
129394
0.06
chr19_40336344_40336545 0.46 FBL
fibrillarin
525
0.75
chr15_101138173_101138360 0.45 LINS
lines homolog (Drosophila)
1125
0.41
chr19_19746136_19746287 0.45 GMIP
GEM interacting protein
2785
0.16
chr2_429739_429917 0.45 FAM150B
family with sequence similarity 150, member B
140977
0.04
chr14_91871423_91871574 0.45 CCDC88C
coiled-coil domain containing 88C
12192
0.23
chr22_20005369_20005520 0.44 TANGO2
transport and golgi organization 2 homolog (Drosophila)
890
0.34
chr19_29700315_29700628 0.44 UQCRFS1
ubiquinol-cytochrome c reductase, Rieske iron-sulfur polypeptide 1
3977
0.3
chr15_91498636_91498821 0.44 AC068831.6

273
0.48
chr14_61844385_61844536 0.44 PRKCH
protein kinase C, eta
12952
0.23
chr1_145153893_145154044 0.44 ENSG00000201789
.
4128
0.24
chrX_148603616_148603869 0.44 IDS
iduronate 2-sulfatase
1107
0.44
chr18_76394598_76394749 0.44 ENSG00000201723
.
90485
0.1
chr17_47814021_47814341 0.44 FAM117A
family with sequence similarity 117, member A
12292
0.14
chr15_90479619_90479888 0.44 C15orf38
chromosome 15 open reading frame 38
23565
0.1
chr3_16355269_16355595 0.43 RP11-415F23.2

514
0.77
chr7_66395703_66395854 0.43 TMEM248
transmembrane protein 248
167
0.95
chr1_26697390_26697759 0.43 ZNF683
zinc finger protein 683
333
0.82
chr19_49179022_49179173 0.43 NTN5
netrin 5
2759
0.12
chr1_120665650_120665841 0.43 ENSG00000207149
.
3817
0.3
chr18_61559637_61559788 0.43 SERPINB2
serpin peptidase inhibitor, clade B (ovalbumin), member 2
1921
0.31
chr1_894146_894297 0.43 NOC2L
nucleolar complex associated 2 homolog (S. cerevisiae)
449
0.63
chr15_60830873_60831064 0.43 CTD-2501E16.2

8796
0.2
chr1_206755327_206755741 0.43 RASSF5
Ras association (RalGDS/AF-6) domain family member 5
25041
0.13
chr15_53098421_53098572 0.43 ONECUT1
one cut homeobox 1
16287
0.27
chr1_155184602_155184753 0.43 RP11-263K19.6

1067
0.21
chr1_100821699_100821850 0.43 CDC14A
cell division cycle 14A
3269
0.24
chr3_48520196_48520441 0.42 SHISA5
shisa family member 5
5701
0.1
chr2_38580024_38580175 0.42 ATL2
atlastin GTPase 2
23267
0.25
chr3_171175083_171175417 0.42 TNIK
TRAF2 and NCK interacting kinase
2602
0.31
chr11_1892605_1892764 0.42 LSP1
lymphocyte-specific protein 1
568
0.59
chr5_54438198_54438349 0.42 GPX8
glutathione peroxidase 8 (putative)
17673
0.11
chr1_169673656_169673937 0.42 SELL
selectin L
7043
0.2
chr17_62346863_62347014 0.42 TEX2
testis expressed 2
6277
0.23
chr14_99667002_99667153 0.42 AL162151.4

42324
0.16
chr6_108048768_108049144 0.42 SCML4
sex comb on midleg-like 4 (Drosophila)
4643
0.33
chr5_57841897_57842048 0.42 CTD-2117L12.1
Uncharacterized protein
12098
0.18
chr2_9984099_9984275 0.42 TAF1B
TATA box binding protein (TBP)-associated factor, RNA polymerase I, B, 63kDa
535
0.83
chr19_8258130_8258343 0.42 CERS4
ceramide synthase 4
13384
0.16
chr9_117668023_117668209 0.42 TNFSF8
tumor necrosis factor (ligand) superfamily, member 8
24581
0.23
chr4_154448725_154449000 0.42 KIAA0922
KIAA0922
28186
0.22
chr3_33049542_33050127 0.42 CCR4
chemokine (C-C motif) receptor 4
56768
0.12
chr6_135449440_135449615 0.41 HBS1L
HBS1-like (S. cerevisiae)
25333
0.18
chr14_23754755_23754960 0.41 HOMEZ
homeobox and leucine zipper encoding
469
0.61
chr17_66343908_66344364 0.41 ARSG
arylsulfatase G
56477
0.1
chr18_2634954_2635303 0.41 ENSG00000202224
.
14039
0.13
chr18_3243897_3244048 0.41 MYL12A
myosin, light chain 12A, regulatory, non-sarcomeric
3507
0.19
chr1_144594079_144594458 0.41 RP11-640M9.2

20863
0.2

Histogram of CRE-TSS distances for CREs targeted by :

Histogram of

Rank distribution of CRE target scores:

Histogram of target CRE score.

Distribution of target CREs across different genomic regions:

Weighted Piechart of Weighted Piechart of Weighted Piechart of

Network of associatons between targets according to the STRING database.

StringDB image

First level regulatory network of NR1H4

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.5 GO:0061526 acetylcholine secretion, neurotransmission(GO:0014055) regulation of acetylcholine secretion, neurotransmission(GO:0014056) acetylcholine secretion(GO:0061526)
0.1 0.6 GO:0046398 UDP-glucuronate metabolic process(GO:0046398)
0.1 0.7 GO:0051569 regulation of histone H3-K4 methylation(GO:0051569)
0.1 0.3 GO:0030223 neutrophil differentiation(GO:0030223)
0.1 0.1 GO:0031062 positive regulation of histone methylation(GO:0031062)
0.1 0.3 GO:1903429 regulation of neuron maturation(GO:0014041) regulation of cell maturation(GO:1903429)
0.1 0.5 GO:0007256 activation of JNKK activity(GO:0007256)
0.1 0.4 GO:0010642 negative regulation of platelet-derived growth factor receptor signaling pathway(GO:0010642)
0.1 0.3 GO:0003077 obsolete negative regulation of diuresis(GO:0003077)
0.1 0.4 GO:0034755 iron ion transmembrane transport(GO:0034755)
0.1 0.2 GO:0061099 negative regulation of protein tyrosine kinase activity(GO:0061099)
0.1 0.2 GO:0035405 histone-threonine phosphorylation(GO:0035405)
0.1 0.6 GO:0007172 signal complex assembly(GO:0007172)
0.1 0.3 GO:0006104 succinyl-CoA metabolic process(GO:0006104)
0.1 0.4 GO:0002726 positive regulation of T cell cytokine production(GO:0002726)
0.1 0.2 GO:0010040 response to iron(II) ion(GO:0010040)
0.1 0.9 GO:0000303 response to superoxide(GO:0000303)
0.1 0.1 GO:0006011 UDP-glucose metabolic process(GO:0006011)
0.1 0.2 GO:0036336 dendritic cell chemotaxis(GO:0002407) dendritic cell migration(GO:0036336)
0.1 0.2 GO:0045990 carbon catabolite regulation of transcription(GO:0045990) regulation of transcription by glucose(GO:0046015)
0.1 0.1 GO:0003148 outflow tract septum morphogenesis(GO:0003148)
0.1 0.2 GO:0000212 meiotic spindle organization(GO:0000212)
0.1 0.4 GO:0032464 positive regulation of protein homooligomerization(GO:0032464)
0.1 0.2 GO:0046137 negative regulation of calcidiol 1-monooxygenase activity(GO:0010956) negative regulation of vitamin D biosynthetic process(GO:0010957) negative regulation of vitamin metabolic process(GO:0046137)
0.1 0.2 GO:0031125 rRNA 3'-end processing(GO:0031125)
0.1 0.3 GO:0090205 positive regulation of cholesterol metabolic process(GO:0090205)
0.1 0.3 GO:0070935 3'-UTR-mediated mRNA stabilization(GO:0070935)
0.1 0.2 GO:0060523 prostate epithelial cord elongation(GO:0060523)
0.1 0.1 GO:0002326 B cell lineage commitment(GO:0002326)
0.1 0.1 GO:0002523 leukocyte migration involved in inflammatory response(GO:0002523)
0.1 0.1 GO:0002874 regulation of chronic inflammatory response to antigenic stimulus(GO:0002874)
0.1 0.4 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.1 0.2 GO:0043985 histone H4-R3 methylation(GO:0043985)
0.1 0.2 GO:0017182 peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183)
0.1 0.1 GO:0030854 positive regulation of granulocyte differentiation(GO:0030854)
0.1 0.4 GO:0009304 tRNA transcription(GO:0009304)
0.1 0.5 GO:0005513 detection of calcium ion(GO:0005513)
0.1 0.1 GO:0018076 N-terminal peptidyl-lysine acetylation(GO:0018076)
0.1 0.2 GO:0070857 regulation of bile acid biosynthetic process(GO:0070857) regulation of bile acid metabolic process(GO:1904251)
0.1 0.2 GO:0003057 regulation of the force of heart contraction by chemical signal(GO:0003057)
0.1 0.2 GO:0032075 positive regulation of nuclease activity(GO:0032075)
0.1 1.0 GO:0050853 B cell receptor signaling pathway(GO:0050853)
0.0 0.1 GO:0002693 positive regulation of cellular extravasation(GO:0002693)
0.0 0.5 GO:0015695 organic cation transport(GO:0015695)
0.0 0.1 GO:0002385 innate immune response in mucosa(GO:0002227) mucosal immune response(GO:0002385)
0.0 0.0 GO:2000758 positive regulation of histone acetylation(GO:0035066) positive regulation of protein acetylation(GO:1901985) positive regulation of peptidyl-lysine acetylation(GO:2000758)
0.0 0.2 GO:0008053 mitochondrial fusion(GO:0008053)
0.0 0.2 GO:0045059 positive thymic T cell selection(GO:0045059)
0.0 0.2 GO:0006685 sphingomyelin catabolic process(GO:0006685)
0.0 0.1 GO:0033152 immunoglobulin V(D)J recombination(GO:0033152)
0.0 0.0 GO:0002691 regulation of cellular extravasation(GO:0002691)
0.0 0.2 GO:0006610 ribosomal protein import into nucleus(GO:0006610)
0.0 0.1 GO:0010831 positive regulation of myotube differentiation(GO:0010831)
0.0 0.2 GO:0021670 lateral ventricle development(GO:0021670)
0.0 0.1 GO:0072203 cell proliferation involved in metanephros development(GO:0072203)
0.0 0.1 GO:0009143 nucleoside triphosphate catabolic process(GO:0009143)
0.0 0.1 GO:0045056 transcytosis(GO:0045056)
0.0 0.2 GO:0042178 xenobiotic catabolic process(GO:0042178)
0.0 0.2 GO:0051016 barbed-end actin filament capping(GO:0051016)
0.0 0.1 GO:0051138 NK T cell differentiation(GO:0001865) regulation of NK T cell differentiation(GO:0051136) positive regulation of NK T cell differentiation(GO:0051138)
0.0 0.2 GO:0031053 primary miRNA processing(GO:0031053)
0.0 0.1 GO:0043653 mitochondrial fragmentation involved in apoptotic process(GO:0043653)
0.0 0.3 GO:0030206 chondroitin sulfate biosynthetic process(GO:0030206)
0.0 0.2 GO:0035025 positive regulation of Rho protein signal transduction(GO:0035025)
0.0 0.2 GO:0032486 Rap protein signal transduction(GO:0032486)
0.0 0.1 GO:0045722 positive regulation of gluconeogenesis(GO:0045722)
0.0 0.0 GO:0051570 regulation of histone H3-K9 methylation(GO:0051570)
0.0 0.2 GO:0010310 regulation of hydrogen peroxide metabolic process(GO:0010310)
0.0 0.1 GO:0045425 positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process(GO:0045425)
0.0 0.5 GO:0032008 positive regulation of TOR signaling(GO:0032008)
0.0 0.1 GO:0002032 desensitization of G-protein coupled receptor protein signaling pathway by arrestin(GO:0002032)
0.0 0.1 GO:0072216 positive regulation of metanephros development(GO:0072216)
0.0 0.3 GO:0051642 centrosome localization(GO:0051642)
0.0 0.1 GO:0002430 complement receptor mediated signaling pathway(GO:0002430)
0.0 0.2 GO:0035162 embryonic hemopoiesis(GO:0035162)
0.0 0.3 GO:0033599 regulation of mammary gland epithelial cell proliferation(GO:0033599)
0.0 0.0 GO:0015904 tetracycline transport(GO:0015904)
0.0 0.1 GO:0060159 regulation of dopamine receptor signaling pathway(GO:0060159)
0.0 0.2 GO:0042989 sequestering of actin monomers(GO:0042989)
0.0 1.1 GO:0050772 positive regulation of axonogenesis(GO:0050772)
0.0 0.1 GO:0006420 arginyl-tRNA aminoacylation(GO:0006420)
0.0 0.0 GO:0071503 response to heparin(GO:0071503)
0.0 0.1 GO:0043247 protection from non-homologous end joining at telomere(GO:0031848) telomere maintenance in response to DNA damage(GO:0043247)
0.0 0.4 GO:0031648 protein destabilization(GO:0031648)
0.0 0.1 GO:0072531 pyrimidine-containing compound transmembrane transport(GO:0072531)
0.0 0.2 GO:0021681 cerebellar granular layer development(GO:0021681) cerebellar granular layer morphogenesis(GO:0021683) cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707)
0.0 0.0 GO:0042492 gamma-delta T cell differentiation(GO:0042492)
0.0 0.1 GO:0001672 regulation of chromatin assembly or disassembly(GO:0001672)
0.0 0.2 GO:0015884 folic acid transport(GO:0015884)
0.0 0.0 GO:0002724 regulation of T cell cytokine production(GO:0002724)
0.0 0.9 GO:0050690 regulation of defense response to virus by virus(GO:0050690)
0.0 0.1 GO:0036037 CD8-positive, alpha-beta T cell activation(GO:0036037) CD8-positive, alpha-beta T cell differentiation(GO:0043374)
0.0 0.1 GO:0031665 negative regulation of lipopolysaccharide-mediated signaling pathway(GO:0031665)
0.0 0.2 GO:0034285 response to sucrose(GO:0009744) response to disaccharide(GO:0034285)
0.0 0.1 GO:0015015 heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.0 0.0 GO:0046642 negative regulation of alpha-beta T cell proliferation(GO:0046642)
0.0 0.3 GO:0040001 establishment of mitotic spindle localization(GO:0040001)
0.0 0.1 GO:0055015 ventricular cardiac muscle cell development(GO:0055015)
0.0 0.1 GO:0045591 positive regulation of regulatory T cell differentiation(GO:0045591)
0.0 0.1 GO:0061154 endothelial tube morphogenesis(GO:0061154)
0.0 0.2 GO:0032933 response to sterol depletion(GO:0006991) SREBP signaling pathway(GO:0032933) cellular response to sterol depletion(GO:0071501)
0.0 0.0 GO:0090286 nuclear matrix organization(GO:0043578) cytoskeletal anchoring at nuclear membrane(GO:0090286) nuclear matrix anchoring at nuclear membrane(GO:0090292)
0.0 0.2 GO:0002507 tolerance induction(GO:0002507)
0.0 0.2 GO:0045116 protein neddylation(GO:0045116)
0.0 0.4 GO:0030252 growth hormone secretion(GO:0030252)
0.0 0.0 GO:0006667 sphinganine metabolic process(GO:0006667)
0.0 0.1 GO:0046618 drug export(GO:0046618)
0.0 0.1 GO:0070682 proteasome regulatory particle assembly(GO:0070682)
0.0 0.2 GO:0002483 antigen processing and presentation of endogenous peptide antigen(GO:0002483) antigen processing and presentation of endogenous peptide antigen via MHC class I(GO:0019885)
0.0 0.2 GO:0033233 regulation of protein sumoylation(GO:0033233) positive regulation of protein sumoylation(GO:0033235)
0.0 0.1 GO:0048147 negative regulation of fibroblast proliferation(GO:0048147)
0.0 0.1 GO:0030187 melatonin metabolic process(GO:0030186) melatonin biosynthetic process(GO:0030187)
0.0 0.1 GO:0006189 'de novo' IMP biosynthetic process(GO:0006189)
0.0 0.1 GO:0072577 endothelial cell apoptotic process(GO:0072577) epithelial cell apoptotic process(GO:1904019) regulation of epithelial cell apoptotic process(GO:1904035) regulation of endothelial cell apoptotic process(GO:2000351)
0.0 0.1 GO:0010452 histone H3-K36 methylation(GO:0010452)
0.0 0.1 GO:0061298 retina vasculature development in camera-type eye(GO:0061298) retina vasculature morphogenesis in camera-type eye(GO:0061299)
0.0 0.6 GO:0007032 endosome organization(GO:0007032)
0.0 0.1 GO:0090231 regulation of spindle checkpoint(GO:0090231)
0.0 0.1 GO:0003283 atrial septum development(GO:0003283) atrial septum morphogenesis(GO:0060413)
0.0 0.1 GO:0048096 chromatin-mediated maintenance of transcription(GO:0048096)
0.0 0.0 GO:2000008 regulation of protein localization to cell surface(GO:2000008)
0.0 0.1 GO:0043490 malate-aspartate shuttle(GO:0043490)
0.0 0.1 GO:0046337 phosphatidylethanolamine biosynthetic process(GO:0006646) phosphatidylethanolamine metabolic process(GO:0046337)
0.0 0.3 GO:0014037 Schwann cell differentiation(GO:0014037)
0.0 0.2 GO:0016556 mRNA modification(GO:0016556)
0.0 0.1 GO:0032226 positive regulation of synaptic transmission, dopaminergic(GO:0032226)
0.0 0.7 GO:0000080 mitotic G1 phase(GO:0000080)
0.0 0.0 GO:0060762 regulation of branching involved in mammary gland duct morphogenesis(GO:0060762)
0.0 0.2 GO:0007191 adenylate cyclase-activating dopamine receptor signaling pathway(GO:0007191)
0.0 0.1 GO:0032288 myelin assembly(GO:0032288)
0.0 0.1 GO:0060836 lymphatic endothelial cell differentiation(GO:0060836)
0.0 0.0 GO:0033591 response to L-ascorbic acid(GO:0033591)
0.0 0.1 GO:0046827 positive regulation of protein export from nucleus(GO:0046827)
0.0 0.1 GO:0001921 positive regulation of receptor recycling(GO:0001921)
0.0 0.1 GO:0045835 negative regulation of meiotic nuclear division(GO:0045835)
0.0 0.1 GO:2000399 negative regulation of T cell differentiation in thymus(GO:0033085) negative regulation of thymocyte aggregation(GO:2000399)
0.0 0.1 GO:0042023 regulation of DNA endoreduplication(GO:0032875) negative regulation of DNA endoreduplication(GO:0032876) DNA endoreduplication(GO:0042023)
0.0 0.1 GO:0071392 cellular response to estradiol stimulus(GO:0071392)
0.0 0.1 GO:0007023 post-chaperonin tubulin folding pathway(GO:0007023)
0.0 0.1 GO:0021978 telencephalon regionalization(GO:0021978)
0.0 0.2 GO:0006198 cAMP catabolic process(GO:0006198)
0.0 0.0 GO:0090322 regulation of superoxide metabolic process(GO:0090322)
0.0 0.4 GO:0032012 regulation of ARF protein signal transduction(GO:0032012)
0.0 0.1 GO:0046968 peptide antigen transport(GO:0046968)
0.0 0.1 GO:0000101 sulfur amino acid transport(GO:0000101) L-cystine transport(GO:0015811)
0.0 0.1 GO:0030505 inorganic diphosphate transport(GO:0030505)
0.0 0.1 GO:0071378 growth hormone receptor signaling pathway(GO:0060396) cellular response to growth hormone stimulus(GO:0071378)
0.0 0.1 GO:0009048 dosage compensation by inactivation of X chromosome(GO:0009048)
0.0 0.1 GO:0072698 protein localization to cytoskeleton(GO:0044380) protein localization to microtubule cytoskeleton(GO:0072698)
0.0 0.2 GO:0006032 chitin metabolic process(GO:0006030) chitin catabolic process(GO:0006032)
0.0 0.1 GO:0070779 D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
0.0 0.1 GO:0045349 interferon-alpha biosynthetic process(GO:0045349) regulation of interferon-alpha biosynthetic process(GO:0045354) positive regulation of interferon-alpha biosynthetic process(GO:0045356)
0.0 0.2 GO:0016255 attachment of GPI anchor to protein(GO:0016255)
0.0 0.4 GO:0034199 activation of protein kinase A activity(GO:0034199)
0.0 0.1 GO:0045898 regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045898)
0.0 0.1 GO:0009138 pyrimidine nucleoside diphosphate metabolic process(GO:0009138)
0.0 0.0 GO:0050774 negative regulation of dendrite morphogenesis(GO:0050774)
0.0 0.1 GO:0000730 DNA recombinase assembly(GO:0000730) double-strand break repair via synthesis-dependent strand annealing(GO:0045003)
0.0 0.0 GO:0071481 cellular response to X-ray(GO:0071481)
0.0 0.1 GO:0014805 smooth muscle adaptation(GO:0014805)
0.0 0.1 GO:0060766 negative regulation of androgen receptor signaling pathway(GO:0060766)
0.0 0.3 GO:0045730 respiratory burst(GO:0045730)
0.0 0.1 GO:0070670 response to interleukin-4(GO:0070670)
0.0 0.1 GO:0021779 oligodendrocyte cell fate commitment(GO:0021779)
0.0 0.7 GO:0043966 histone H3 acetylation(GO:0043966)
0.0 0.1 GO:0048711 positive regulation of astrocyte differentiation(GO:0048711)
0.0 0.0 GO:0048478 replication fork protection(GO:0048478)
0.0 0.0 GO:0032509 endosome transport via multivesicular body sorting pathway(GO:0032509)
0.0 0.1 GO:0030488 tRNA methylation(GO:0030488)
0.0 0.1 GO:0006857 oligopeptide transport(GO:0006857)
0.0 0.1 GO:1900087 traversing start control point of mitotic cell cycle(GO:0007089) positive regulation of G1/S transition of mitotic cell cycle(GO:1900087) positive regulation of cell cycle G1/S phase transition(GO:1902808)
0.0 0.0 GO:0042726 flavin-containing compound metabolic process(GO:0042726)
0.0 0.1 GO:0015825 L-serine transport(GO:0015825)
0.0 0.0 GO:0019884 antigen processing and presentation of exogenous antigen(GO:0019884)
0.0 0.1 GO:0006552 leucine catabolic process(GO:0006552)
0.0 0.1 GO:0033145 positive regulation of intracellular steroid hormone receptor signaling pathway(GO:0033145)
0.0 0.1 GO:0045885 obsolete positive regulation of survival gene product expression(GO:0045885)
0.0 0.1 GO:1903393 positive regulation of focal adhesion assembly(GO:0051894) positive regulation of cell junction assembly(GO:1901890) positive regulation of adherens junction organization(GO:1903393)
0.0 0.0 GO:0032747 interleukin-23 production(GO:0032627) regulation of interleukin-23 production(GO:0032667) positive regulation of interleukin-23 production(GO:0032747)
0.0 0.0 GO:0002313 mature B cell differentiation involved in immune response(GO:0002313)
0.0 0.4 GO:0046677 response to antibiotic(GO:0046677)
0.0 0.2 GO:0060742 epithelial cell differentiation involved in prostate gland development(GO:0060742)
0.0 0.1 GO:0006689 ganglioside catabolic process(GO:0006689)
0.0 0.2 GO:0015939 pantothenate metabolic process(GO:0015939)
0.0 0.0 GO:0046007 negative regulation of activated T cell proliferation(GO:0046007)
0.0 0.2 GO:0043508 negative regulation of JUN kinase activity(GO:0043508)
0.0 0.9 GO:0031294 lymphocyte costimulation(GO:0031294) T cell costimulation(GO:0031295)
0.0 0.1 GO:0034626 fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.0 0.1 GO:0060456 positive regulation of digestive system process(GO:0060456)
0.0 0.1 GO:0010591 regulation of lamellipodium assembly(GO:0010591)
0.0 0.0 GO:0033688 regulation of osteoblast proliferation(GO:0033688)
0.0 0.1 GO:0050685 positive regulation of mRNA 3'-end processing(GO:0031442) positive regulation of mRNA processing(GO:0050685) positive regulation of mRNA metabolic process(GO:1903313)
0.0 0.1 GO:0007635 chemosensory behavior(GO:0007635)
0.0 0.4 GO:0007030 Golgi organization(GO:0007030)
0.0 0.1 GO:0071318 cellular response to ATP(GO:0071318)
0.0 0.0 GO:0021781 glial cell fate commitment(GO:0021781)
0.0 0.1 GO:0002830 positive regulation of type 2 immune response(GO:0002830)
0.0 0.0 GO:0003197 endocardial cushion development(GO:0003197)
0.0 0.2 GO:0006044 N-acetylglucosamine metabolic process(GO:0006044)
0.0 0.0 GO:0001661 conditioned taste aversion(GO:0001661)
0.0 0.1 GO:0019852 L-ascorbic acid metabolic process(GO:0019852)
0.0 0.1 GO:0001866 NK T cell proliferation(GO:0001866)
0.0 0.0 GO:0045086 positive regulation of interleukin-2 biosynthetic process(GO:0045086)
0.0 0.0 GO:0003323 type B pancreatic cell development(GO:0003323)
0.0 0.2 GO:0045197 establishment or maintenance of epithelial cell apical/basal polarity(GO:0045197)
0.0 0.1 GO:0043951 negative regulation of cAMP-mediated signaling(GO:0043951)
0.0 0.4 GO:0033209 tumor necrosis factor-mediated signaling pathway(GO:0033209)
0.0 0.1 GO:0006474 N-terminal protein amino acid acetylation(GO:0006474)
0.0 0.5 GO:0042147 retrograde transport, endosome to Golgi(GO:0042147)
0.0 0.1 GO:0006167 AMP biosynthetic process(GO:0006167)
0.0 0.1 GO:0045634 regulation of melanocyte differentiation(GO:0045634) regulation of pigment cell differentiation(GO:0050932)
0.0 0.1 GO:0001574 ganglioside biosynthetic process(GO:0001574)
0.0 0.1 GO:0009303 rRNA transcription(GO:0009303)
0.0 0.1 GO:0015886 heme transport(GO:0015886)
0.0 0.0 GO:0032497 detection of lipopolysaccharide(GO:0032497)
0.0 0.0 GO:0046940 nucleoside monophosphate phosphorylation(GO:0046940)
0.0 0.0 GO:0045579 positive regulation of B cell differentiation(GO:0045579)
0.0 0.0 GO:0042339 keratan sulfate metabolic process(GO:0042339)
0.0 0.0 GO:1901797 negative regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043518) negative regulation of signal transduction by p53 class mediator(GO:1901797)
0.0 0.2 GO:0006906 vesicle fusion(GO:0006906)
0.0 0.0 GO:0070932 histone H3 deacetylation(GO:0070932) histone H4 deacetylation(GO:0070933)
0.0 0.1 GO:0008535 respiratory chain complex IV assembly(GO:0008535)
0.0 0.0 GO:0016242 negative regulation of macroautophagy(GO:0016242)
0.0 0.0 GO:0045603 positive regulation of endothelial cell differentiation(GO:0045603)
0.0 0.1 GO:0003056 regulation of vascular smooth muscle contraction(GO:0003056)
0.0 0.8 GO:0006968 cellular defense response(GO:0006968)
0.0 0.1 GO:0007008 outer mitochondrial membrane organization(GO:0007008) protein import into mitochondrial outer membrane(GO:0045040)
0.0 0.2 GO:0006107 oxaloacetate metabolic process(GO:0006107)
0.0 0.0 GO:2000318 T-helper cell lineage commitment(GO:0002295) alpha-beta T cell lineage commitment(GO:0002363) CD4-positive or CD8-positive, alpha-beta T cell lineage commitment(GO:0043369) CD4-positive, alpha-beta T cell lineage commitment(GO:0043373) memory T cell differentiation(GO:0043379) regulation of memory T cell differentiation(GO:0043380) positive regulation of memory T cell differentiation(GO:0043382) T-helper 17 type immune response(GO:0072538) T-helper 17 cell differentiation(GO:0072539) T-helper 17 cell lineage commitment(GO:0072540) regulation of T-helper 17 type immune response(GO:2000316) positive regulation of T-helper 17 type immune response(GO:2000318) regulation of T-helper 17 cell differentiation(GO:2000319) positive regulation of T-helper 17 cell differentiation(GO:2000321) regulation of T-helper 17 cell lineage commitment(GO:2000328) positive regulation of T-helper 17 cell lineage commitment(GO:2000330)
0.0 1.1 GO:0071357 type I interferon signaling pathway(GO:0060337) cellular response to type I interferon(GO:0071357)
0.0 0.1 GO:0043045 DNA methylation involved in embryo development(GO:0043045) changes to DNA methylation involved in embryo development(GO:1901538)
0.0 0.0 GO:0071364 cellular response to epidermal growth factor stimulus(GO:0071364)
0.0 0.1 GO:0060235 lens induction in camera-type eye(GO:0060235)
0.0 0.1 GO:0032455 nerve growth factor processing(GO:0032455)
0.0 0.0 GO:0002689 negative regulation of leukocyte chemotaxis(GO:0002689)
0.0 0.1 GO:0030033 microvillus assembly(GO:0030033) microvillus organization(GO:0032528)
0.0 0.0 GO:0016233 telomere capping(GO:0016233)
0.0 0.1 GO:0033962 cytoplasmic mRNA processing body assembly(GO:0033962)
0.0 0.0 GO:0060996 dendritic spine development(GO:0060996)
0.0 0.1 GO:0034227 tRNA wobble base modification(GO:0002097) tRNA wobble uridine modification(GO:0002098) tRNA thio-modification(GO:0034227)
0.0 0.3 GO:0006362 transcription elongation from RNA polymerase I promoter(GO:0006362)
0.0 0.0 GO:0032922 circadian regulation of gene expression(GO:0032922)
0.0 0.1 GO:0006657 CDP-choline pathway(GO:0006657)
0.0 0.1 GO:0042749 regulation of circadian sleep/wake cycle(GO:0042749) regulation of circadian sleep/wake cycle, sleep(GO:0045187)
0.0 0.1 GO:0045948 positive regulation of translational initiation(GO:0045948)
0.0 0.0 GO:0050765 negative regulation of phagocytosis(GO:0050765)
0.0 0.2 GO:0015669 gas transport(GO:0015669)
0.0 0.0 GO:0044240 multicellular organism lipid catabolic process(GO:0044240)
0.0 0.1 GO:0051567 histone H3-K9 methylation(GO:0051567) histone H3-K9 modification(GO:0061647)
0.0 1.1 GO:0008033 tRNA processing(GO:0008033)
0.0 0.0 GO:0007195 adenylate cyclase-inhibiting dopamine receptor signaling pathway(GO:0007195)
0.0 0.1 GO:0009812 flavonoid metabolic process(GO:0009812)
0.0 0.1 GO:0001782 B cell homeostasis(GO:0001782)
0.0 0.1 GO:0061001 dendritic spine morphogenesis(GO:0060997) regulation of dendritic spine morphogenesis(GO:0061001) dendritic spine organization(GO:0097061)
0.0 0.0 GO:0097502 protein mannosylation(GO:0035268) protein O-linked mannosylation(GO:0035269) mannosylation(GO:0097502)
0.0 0.2 GO:0006297 nucleotide-excision repair, DNA gap filling(GO:0006297)
0.0 0.0 GO:0052251 induction by organism of defense response of other organism involved in symbiotic interaction(GO:0052251)
0.0 0.3 GO:0034724 DNA replication-independent nucleosome assembly(GO:0006336) CENP-A containing nucleosome assembly(GO:0034080) DNA replication-independent nucleosome organization(GO:0034724) CENP-A containing chromatin organization(GO:0061641)
0.0 0.0 GO:0017085 response to insecticide(GO:0017085)
0.0 0.0 GO:0031034 skeletal muscle myosin thick filament assembly(GO:0030241) myosin filament organization(GO:0031033) myosin filament assembly(GO:0031034) striated muscle myosin thick filament assembly(GO:0071688)
0.0 0.0 GO:0032202 telomere assembly(GO:0032202)
0.0 0.0 GO:0010940 positive regulation of necrotic cell death(GO:0010940)
0.0 0.0 GO:0060406 positive regulation of penile erection(GO:0060406)
0.0 0.1 GO:0045737 positive regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045737) positive regulation of cyclin-dependent protein kinase activity(GO:1904031)
0.0 0.0 GO:0045945 positive regulation of transcription from RNA polymerase III promoter(GO:0045945)
0.0 0.0 GO:0048284 organelle fusion(GO:0048284)
0.0 0.0 GO:0006432 phenylalanyl-tRNA aminoacylation(GO:0006432)
0.0 0.1 GO:0033327 Leydig cell differentiation(GO:0033327)
0.0 0.1 GO:0051290 protein heterotetramerization(GO:0051290)
0.0 0.0 GO:0007262 STAT protein import into nucleus(GO:0007262)
0.0 0.1 GO:0048630 skeletal muscle tissue growth(GO:0048630)
0.0 0.1 GO:0006560 proline metabolic process(GO:0006560)
0.0 0.2 GO:0048484 enteric nervous system development(GO:0048484)
0.0 0.1 GO:0006983 ER overload response(GO:0006983)
0.0 0.0 GO:0060251 regulation of glial cell proliferation(GO:0060251)
0.0 0.0 GO:0032070 regulation of deoxyribonuclease activity(GO:0032070)
0.0 0.1 GO:0048535 lymph node development(GO:0048535)
0.0 0.0 GO:0060206 estrous cycle phase(GO:0060206)
0.0 0.0 GO:0051176 positive regulation of sulfur metabolic process(GO:0051176)
0.0 0.1 GO:0035082 axoneme assembly(GO:0035082)
0.0 0.2 GO:0006098 pentose-phosphate shunt(GO:0006098) glyceraldehyde-3-phosphate metabolic process(GO:0019682)
0.0 0.1 GO:0042756 drinking behavior(GO:0042756)
0.0 0.1 GO:0022614 membrane to membrane docking(GO:0022614)
0.0 0.1 GO:0072506 phosphate ion homeostasis(GO:0055062) divalent inorganic anion homeostasis(GO:0072505) trivalent inorganic anion homeostasis(GO:0072506)
0.0 0.2 GO:0000045 autophagosome assembly(GO:0000045) autophagosome organization(GO:1905037)
0.0 0.1 GO:0015074 DNA integration(GO:0015074)
0.0 0.0 GO:0033024 mast cell homeostasis(GO:0033023) mast cell apoptotic process(GO:0033024) regulation of mast cell apoptotic process(GO:0033025)
0.0 0.0 GO:0048302 regulation of isotype switching to IgG isotypes(GO:0048302)
0.0 0.0 GO:0035246 peptidyl-arginine N-methylation(GO:0035246)
0.0 0.0 GO:0015705 iodide transport(GO:0015705)
0.0 0.0 GO:0032695 negative regulation of interleukin-12 production(GO:0032695)
0.0 0.0 GO:0032790 ribosome disassembly(GO:0032790)
0.0 0.0 GO:0000239 pachytene(GO:0000239)
0.0 0.1 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.0 0.0 GO:0048070 regulation of developmental pigmentation(GO:0048070)
0.0 0.0 GO:0042670 retinal cone cell differentiation(GO:0042670) retinal cone cell development(GO:0046549)
0.0 0.1 GO:0003084 positive regulation of systemic arterial blood pressure(GO:0003084)
0.0 0.1 GO:0050798 activated T cell proliferation(GO:0050798)
0.0 0.1 GO:0007158 neuron cell-cell adhesion(GO:0007158)
0.0 0.1 GO:0000154 rRNA modification(GO:0000154)
0.0 0.1 GO:0006999 nuclear pore organization(GO:0006999)
0.0 0.0 GO:0071883 adrenergic receptor signaling pathway(GO:0071875) activation of MAPK activity by adrenergic receptor signaling pathway(GO:0071883)
0.0 0.1 GO:0007020 microtubule nucleation(GO:0007020)
0.0 0.1 GO:0019987 obsolete negative regulation of anti-apoptosis(GO:0019987)
0.0 0.2 GO:0006611 protein export from nucleus(GO:0006611)
0.0 0.0 GO:0032898 neurotrophin production(GO:0032898)
0.0 0.0 GO:0008608 attachment of spindle microtubules to kinetochore(GO:0008608)
0.0 0.0 GO:0032968 positive regulation of transcription elongation from RNA polymerase II promoter(GO:0032968)
0.0 0.2 GO:0048536 spleen development(GO:0048536)
0.0 0.0 GO:1901419 regulation of response to alcohol(GO:1901419)
0.0 0.3 GO:0002429 immune response-activating cell surface receptor signaling pathway(GO:0002429)
0.0 0.0 GO:0098781 ncRNA transcription(GO:0098781)
0.0 0.0 GO:0071569 protein ufmylation(GO:0071569)
0.0 0.0 GO:0010755 regulation of plasminogen activation(GO:0010755)
0.0 0.0 GO:0035092 sperm chromatin condensation(GO:0035092)
0.0 0.1 GO:0007141 male meiosis I(GO:0007141)
0.0 0.0 GO:0045359 interferon-beta biosynthetic process(GO:0045350) regulation of interferon-beta biosynthetic process(GO:0045357) positive regulation of interferon-beta biosynthetic process(GO:0045359)
0.0 0.1 GO:0007096 regulation of exit from mitosis(GO:0007096)
0.0 0.0 GO:0043501 skeletal muscle adaptation(GO:0043501)
0.0 0.5 GO:0051092 positive regulation of NF-kappaB transcription factor activity(GO:0051092)
0.0 0.0 GO:0043276 anoikis(GO:0043276)
0.0 0.0 GO:0090026 regulation of monocyte chemotaxis(GO:0090025) positive regulation of monocyte chemotaxis(GO:0090026)
0.0 0.1 GO:0007320 insemination(GO:0007320)
0.0 0.1 GO:0034214 protein hexamerization(GO:0034214)
0.0 0.2 GO:0042273 ribosomal large subunit biogenesis(GO:0042273)
0.0 0.2 GO:0030520 intracellular estrogen receptor signaling pathway(GO:0030520)
0.0 0.1 GO:0048268 clathrin coat assembly(GO:0048268)
0.0 0.0 GO:1903579 negative regulation of nucleoside metabolic process(GO:0045978) negative regulation of ATP metabolic process(GO:1903579)
0.0 0.2 GO:0016601 Rac protein signal transduction(GO:0016601)
0.0 0.1 GO:0018345 protein palmitoylation(GO:0018345)
0.0 0.1 GO:0046501 protoporphyrinogen IX metabolic process(GO:0046501)
0.0 0.0 GO:0072678 T cell chemotaxis(GO:0010818) regulation of T cell chemotaxis(GO:0010819) positive regulation of T cell chemotaxis(GO:0010820) T cell migration(GO:0072678) regulation of lymphocyte chemotaxis(GO:1901623) regulation of lymphocyte migration(GO:2000401) positive regulation of lymphocyte migration(GO:2000403) regulation of T cell migration(GO:2000404) positive regulation of T cell migration(GO:2000406)
0.0 0.0 GO:0050665 hydrogen peroxide biosynthetic process(GO:0050665)
0.0 0.3 GO:0042059 negative regulation of epidermal growth factor receptor signaling pathway(GO:0042059) negative regulation of ERBB signaling pathway(GO:1901185)
0.0 0.1 GO:0031272 pseudopodium assembly(GO:0031269) regulation of pseudopodium assembly(GO:0031272) positive regulation of pseudopodium assembly(GO:0031274)
0.0 0.2 GO:0051225 spindle assembly(GO:0051225)
0.0 0.0 GO:0046633 alpha-beta T cell proliferation(GO:0046633)
0.0 0.0 GO:0045071 negative regulation of viral genome replication(GO:0045071)
0.0 0.1 GO:0006801 superoxide metabolic process(GO:0006801)
0.0 0.0 GO:0035751 lysosomal lumen acidification(GO:0007042) regulation of lysosomal lumen pH(GO:0035751)
0.0 0.2 GO:0006691 leukotriene metabolic process(GO:0006691)
0.0 0.1 GO:0034260 negative regulation of GTPase activity(GO:0034260)
0.0 0.0 GO:0042091 interleukin-10 biosynthetic process(GO:0042091) regulation of interleukin-10 biosynthetic process(GO:0045074)
0.0 0.1 GO:0015693 magnesium ion transport(GO:0015693)
0.0 0.0 GO:0045647 negative regulation of erythrocyte differentiation(GO:0045647)
0.0 0.0 GO:0015691 cadmium ion transport(GO:0015691) cadmium ion transmembrane transport(GO:0070574)
0.0 0.1 GO:0007080 mitotic metaphase plate congression(GO:0007080)
0.0 0.1 GO:0051568 histone H3-K4 methylation(GO:0051568)
0.0 0.0 GO:0010738 regulation of protein kinase A signaling(GO:0010738)
0.0 0.1 GO:0008625 extrinsic apoptotic signaling pathway via death domain receptors(GO:0008625) extrinsic apoptotic signaling pathway(GO:0097191)
0.0 0.0 GO:0019276 UDP-N-acetylgalactosamine metabolic process(GO:0019276)
0.0 0.0 GO:1901341 activation of store-operated calcium channel activity(GO:0032237) regulation of store-operated calcium channel activity(GO:1901339) positive regulation of store-operated calcium channel activity(GO:1901341)
0.0 0.0 GO:0009215 purine deoxyribonucleoside triphosphate metabolic process(GO:0009215)
0.0 0.0 GO:0072677 eosinophil chemotaxis(GO:0048245) eosinophil migration(GO:0072677)
0.0 0.2 GO:0007422 peripheral nervous system development(GO:0007422)
0.0 0.1 GO:0014823 response to activity(GO:0014823)
0.0 0.1 GO:0006546 glycine catabolic process(GO:0006546)
0.0 0.0 GO:0033033 negative regulation of myeloid cell apoptotic process(GO:0033033)
0.0 0.1 GO:0006895 Golgi to endosome transport(GO:0006895) Golgi to vacuole transport(GO:0006896)
0.0 0.0 GO:0032927 positive regulation of activin receptor signaling pathway(GO:0032927)
0.0 0.0 GO:0048739 cardiac muscle fiber development(GO:0048739)
0.0 0.0 GO:0048485 sympathetic nervous system development(GO:0048485)
0.0 0.1 GO:0001578 microtubule bundle formation(GO:0001578)
0.0 0.1 GO:0007216 G-protein coupled glutamate receptor signaling pathway(GO:0007216)
0.0 0.1 GO:0042744 hydrogen peroxide catabolic process(GO:0042744)
0.0 0.0 GO:0042441 eye pigment biosynthetic process(GO:0006726) eye pigment metabolic process(GO:0042441) pigment metabolic process involved in developmental pigmentation(GO:0043324) pigment metabolic process involved in pigmentation(GO:0043474)
0.0 0.0 GO:0015917 aminophospholipid transport(GO:0015917)
0.0 0.1 GO:0045670 regulation of osteoclast differentiation(GO:0045670)
0.0 0.0 GO:0006361 transcription initiation from RNA polymerase I promoter(GO:0006361)
0.0 0.1 GO:0048172 regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.0 0.1 GO:0006020 inositol metabolic process(GO:0006020)
0.0 0.2 GO:0032480 negative regulation of type I interferon production(GO:0032480)
0.0 0.0 GO:0050651 dermatan sulfate proteoglycan biosynthetic process(GO:0050651)
0.0 0.1 GO:0046339 diacylglycerol metabolic process(GO:0046339)
0.0 0.1 GO:0000076 DNA replication checkpoint(GO:0000076)
0.0 0.0 GO:0046101 hypoxanthine biosynthetic process(GO:0046101)
0.0 0.2 GO:0030261 chromosome condensation(GO:0030261)
0.0 0.0 GO:0048291 isotype switching to IgG isotypes(GO:0048291)
0.0 0.1 GO:0019042 viral latency(GO:0019042)
0.0 0.1 GO:0009083 branched-chain amino acid catabolic process(GO:0009083)
0.0 0.1 GO:0006684 sphingomyelin metabolic process(GO:0006684)
0.0 0.0 GO:0090085 regulation of protein deubiquitination(GO:0090085)
0.0 0.0 GO:0007217 tachykinin receptor signaling pathway(GO:0007217)
0.0 0.0 GO:0046607 positive regulation of centrosome cycle(GO:0046607)
0.0 0.0 GO:0090073 positive regulation of protein homodimerization activity(GO:0090073)
0.0 0.0 GO:0009804 phenylpropanoid metabolic process(GO:0009698) coumarin metabolic process(GO:0009804)
0.0 0.1 GO:0006554 lysine metabolic process(GO:0006553) lysine catabolic process(GO:0006554)
0.0 0.1 GO:0006750 glutathione biosynthetic process(GO:0006750)
0.0 0.0 GO:0045292 mRNA cis splicing, via spliceosome(GO:0045292)
0.0 0.0 GO:0035054 embryonic heart tube anterior/posterior pattern specification(GO:0035054)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0031932 TORC2 complex(GO:0031932)
0.1 0.4 GO:0001652 granular component(GO:0001652)
0.1 0.6 GO:0070775 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.1 0.3 GO:0000306 extrinsic component of vacuolar membrane(GO:0000306) extrinsic component of endosome membrane(GO:0031313)
0.1 0.4 GO:0005826 actomyosin contractile ring(GO:0005826)
0.1 0.6 GO:0030673 axolemma(GO:0030673)
0.1 0.2 GO:0043218 compact myelin(GO:0043218)
0.1 0.4 GO:0090576 RNA polymerase III transcription factor complex(GO:0090576)
0.1 0.1 GO:0031306 intrinsic component of mitochondrial outer membrane(GO:0031306)
0.0 0.2 GO:0005750 mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
0.0 0.3 GO:0001891 phagocytic cup(GO:0001891)
0.0 0.1 GO:0032444 activin responsive factor complex(GO:0032444)
0.0 0.3 GO:0043190 ATP-binding cassette (ABC) transporter complex(GO:0043190)
0.0 0.4 GO:0035631 CD40 receptor complex(GO:0035631)
0.0 0.1 GO:0016533 cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533)
0.0 0.2 GO:0001740 Barr body(GO:0001740)
0.0 0.1 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.0 0.5 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.0 0.2 GO:0042765 GPI-anchor transamidase complex(GO:0042765)
0.0 0.2 GO:0005663 DNA replication factor C complex(GO:0005663)
0.0 0.4 GO:0030288 outer membrane-bounded periplasmic space(GO:0030288) periplasmic space(GO:0042597)
0.0 0.2 GO:0070688 MLL5-L complex(GO:0070688)
0.0 0.3 GO:0005861 troponin complex(GO:0005861)
0.0 0.2 GO:0070695 FHF complex(GO:0070695)
0.0 0.2 GO:0016461 unconventional myosin complex(GO:0016461)
0.0 0.1 GO:0016589 NURF complex(GO:0016589)
0.0 0.4 GO:0001772 immunological synapse(GO:0001772)
0.0 0.2 GO:0005828 kinetochore microtubule(GO:0005828)
0.0 0.1 GO:1990316 ATG1/ULK1 kinase complex(GO:1990316)
0.0 0.2 GO:0045179 apical cortex(GO:0045179)
0.0 0.2 GO:0005883 neurofilament(GO:0005883)
0.0 0.1 GO:0034992 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.0 0.4 GO:0016585 obsolete chromatin remodeling complex(GO:0016585)
0.0 0.1 GO:0008540 proteasome regulatory particle, base subcomplex(GO:0008540)
0.0 0.1 GO:0000942 condensed nuclear chromosome outer kinetochore(GO:0000942)
0.0 0.1 GO:0017059 palmitoyltransferase complex(GO:0002178) serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211)
0.0 0.1 GO:0031088 platelet dense granule membrane(GO:0031088)
0.0 0.1 GO:0042587 glycogen granule(GO:0042587)
0.0 0.2 GO:0031264 death-inducing signaling complex(GO:0031264)
0.0 0.3 GO:0000242 pericentriolar material(GO:0000242)
0.0 0.1 GO:0035145 exon-exon junction complex(GO:0035145)
0.0 0.2 GO:0030681 nucleolar ribonuclease P complex(GO:0005655) ribonuclease P complex(GO:0030677) multimeric ribonuclease P complex(GO:0030681)
0.0 0.1 GO:0070820 tertiary granule(GO:0070820)
0.0 0.1 GO:0034045 pre-autophagosomal structure membrane(GO:0034045)
0.0 0.1 GO:0005863 striated muscle myosin thick filament(GO:0005863)
0.0 0.1 GO:0035189 Rb-E2F complex(GO:0035189)
0.0 0.1 GO:0031616 spindle pole centrosome(GO:0031616)
0.0 0.0 GO:0030313 cell envelope(GO:0030313)
0.0 0.1 GO:0005900 oncostatin-M receptor complex(GO:0005900)
0.0 0.1 GO:0030008 TRAPP complex(GO:0030008)
0.0 0.4 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 0.4 GO:0005811 lipid particle(GO:0005811)
0.0 0.1 GO:0044224 juxtaparanode region of axon(GO:0044224)
0.0 0.4 GO:0031519 PcG protein complex(GO:0031519)
0.0 0.1 GO:0031254 uropod(GO:0001931) cell trailing edge(GO:0031254)
0.0 0.2 GO:0031528 microvillus membrane(GO:0031528)
0.0 0.1 GO:0031618 nuclear pericentric heterochromatin(GO:0031618)
0.0 0.1 GO:0008290 F-actin capping protein complex(GO:0008290)
0.0 0.2 GO:0042101 T cell receptor complex(GO:0042101)
0.0 0.0 GO:0031501 mannosyltransferase complex(GO:0031501) dolichol-phosphate-mannose synthase complex(GO:0033185)
0.0 0.0 GO:0033268 node of Ranvier(GO:0033268)
0.0 0.0 GO:0071986 Ragulator complex(GO:0071986)
0.0 0.1 GO:0042584 chromaffin granule(GO:0042583) chromaffin granule membrane(GO:0042584)
0.0 0.2 GO:0008278 cohesin complex(GO:0008278)
0.0 0.1 GO:0005662 DNA replication factor A complex(GO:0005662)
0.0 0.2 GO:0005640 nuclear outer membrane(GO:0005640)
0.0 0.0 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.0 0.1 GO:0017071 intracellular cyclic nucleotide activated cation channel complex(GO:0017071)
0.0 0.0 GO:0031931 TORC1 complex(GO:0031931)
0.0 0.1 GO:0043202 lysosomal lumen(GO:0043202)
0.0 0.0 GO:0044298 neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.0 0.2 GO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
0.0 0.1 GO:0048188 Set1C/COMPASS complex(GO:0048188)
0.0 0.2 GO:0042588 zymogen granule(GO:0042588)
0.0 0.1 GO:0043020 NADPH oxidase complex(GO:0043020)
0.0 0.2 GO:0030530 obsolete heterogeneous nuclear ribonucleoprotein complex(GO:0030530)
0.0 0.7 GO:0031228 intrinsic component of Golgi membrane(GO:0031228)
0.0 0.7 GO:0055037 recycling endosome(GO:0055037)
0.0 0.1 GO:0000137 Golgi cis cisterna(GO:0000137)
0.0 0.5 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 0.2 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.0 0.3 GO:0030286 dynein complex(GO:0030286)
0.0 0.0 GO:0032593 insulin-responsive compartment(GO:0032593)
0.0 0.1 GO:0046540 U4/U6 x U5 tri-snRNP complex(GO:0046540) spliceosomal tri-snRNP complex(GO:0097526)
0.0 0.0 GO:0033150 cytoskeletal calyx(GO:0033150)
0.0 0.1 GO:0032039 integrator complex(GO:0032039)
0.0 0.0 GO:0008537 proteasome activator complex(GO:0008537)
0.0 0.1 GO:0005677 chromatin silencing complex(GO:0005677)
0.0 0.2 GO:0005771 multivesicular body(GO:0005771)
0.0 0.3 GO:0005921 gap junction(GO:0005921)
0.0 0.1 GO:0000153 cytoplasmic ubiquitin ligase complex(GO:0000153)
0.0 0.1 GO:0000796 condensin complex(GO:0000796)
0.0 0.0 GO:0032133 chromosome passenger complex(GO:0032133)
0.0 0.1 GO:0032389 MutLalpha complex(GO:0032389)
0.0 0.2 GO:0044447 axoneme part(GO:0044447)
0.0 0.3 GO:0098562 cytoplasmic side of membrane(GO:0098562)
0.0 0.0 GO:0098573 intrinsic component of mitochondrial inner membrane(GO:0031304) intrinsic component of mitochondrial membrane(GO:0098573)
0.0 0.1 GO:0005885 Arp2/3 protein complex(GO:0005885)
0.0 0.9 GO:0031301 integral component of organelle membrane(GO:0031301)
0.0 0.2 GO:0044665 MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339)
0.0 0.1 GO:0000780 condensed nuclear chromosome, centromeric region(GO:0000780)
0.0 0.1 GO:0005847 mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.0 0.5 GO:0016459 myosin complex(GO:0016459)
0.0 0.4 GO:0045271 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0 0.1 GO:0000782 telomere cap complex(GO:0000782) nuclear telomere cap complex(GO:0000783)
0.0 0.1 GO:0016442 RISC complex(GO:0016442) RNAi effector complex(GO:0031332)
0.0 0.2 GO:0046930 pore complex(GO:0046930)
0.0 0.1 GO:0042598 obsolete vesicular fraction(GO:0042598)
0.0 0.1 GO:0031941 filamentous actin(GO:0031941)
0.0 0.0 GO:0070062 extracellular exosome(GO:0070062) extracellular vesicle(GO:1903561)
0.0 0.3 GO:0000794 condensed nuclear chromosome(GO:0000794)
0.0 0.1 GO:0031080 nuclear pore outer ring(GO:0031080)
0.0 0.8 GO:0048770 melanosome(GO:0042470) pigment granule(GO:0048770)
0.0 0.1 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.0 0.1 GO:0090568 NuRD complex(GO:0016581) CHD-type complex(GO:0090545) nuclear transcriptional repressor complex(GO:0090568)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.6 GO:0015199 amino-acid betaine transmembrane transporter activity(GO:0015199) carnitine transmembrane transporter activity(GO:0015226)
0.2 0.5 GO:0047631 ADP-ribose diphosphatase activity(GO:0047631)
0.1 0.4 GO:0016309 1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
0.1 0.4 GO:0031014 troponin T binding(GO:0031014)
0.1 0.3 GO:0003836 beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.1 0.5 GO:0001609 G-protein coupled adenosine receptor activity(GO:0001609)
0.1 0.3 GO:0044020 histone methyltransferase activity (H4-R3 specific)(GO:0044020)
0.1 0.3 GO:0030284 estrogen receptor activity(GO:0030284)
0.1 0.2 GO:0015018 galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity(GO:0015018)
0.1 0.2 GO:0004911 interleukin-2 receptor activity(GO:0004911)
0.1 0.2 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.1 0.2 GO:0035184 histone threonine kinase activity(GO:0035184)
0.1 0.3 GO:0004706 JUN kinase kinase kinase activity(GO:0004706)
0.1 0.4 GO:0015165 pyrimidine nucleotide-sugar transmembrane transporter activity(GO:0015165)
0.1 0.3 GO:0004774 succinate-CoA ligase activity(GO:0004774)
0.1 0.2 GO:0017159 pantetheine hydrolase activity(GO:0017159)
0.1 0.3 GO:0047238 glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity(GO:0047238)
0.1 0.2 GO:0003726 double-stranded RNA adenosine deaminase activity(GO:0003726)
0.1 0.1 GO:0005176 ErbB-2 class receptor binding(GO:0005176)
0.1 0.3 GO:0005381 iron ion transmembrane transporter activity(GO:0005381)
0.1 0.2 GO:0008321 Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.1 0.1 GO:1901474 azole transporter activity(GO:0045118) azole transmembrane transporter activity(GO:1901474)
0.1 0.2 GO:0008518 reduced folate carrier activity(GO:0008518)
0.1 0.2 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.1 0.2 GO:0003953 NAD+ nucleosidase activity(GO:0003953)
0.1 0.2 GO:0030292 protein tyrosine kinase inhibitor activity(GO:0030292)
0.1 0.2 GO:0050321 tau-protein kinase activity(GO:0050321)
0.1 0.2 GO:0016312 inositol bisphosphate phosphatase activity(GO:0016312)
0.0 0.2 GO:0031694 alpha-2A adrenergic receptor binding(GO:0031694)
0.0 0.2 GO:0016717 oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water(GO:0016717)
0.0 0.0 GO:0051380 beta-adrenergic receptor activity(GO:0004939) norepinephrine binding(GO:0051380)
0.0 0.5 GO:0003709 obsolete RNA polymerase III transcription factor activity(GO:0003709)
0.0 0.5 GO:0016493 C-C chemokine receptor activity(GO:0016493)
0.0 0.2 GO:0031690 adrenergic receptor binding(GO:0031690)
0.0 0.2 GO:0005000 vasopressin receptor activity(GO:0005000)
0.0 0.3 GO:0004969 histamine receptor activity(GO:0004969)
0.0 0.3 GO:0019789 SUMO transferase activity(GO:0019789)
0.0 0.1 GO:0033691 sialic acid binding(GO:0033691)
0.0 0.1 GO:0016842 amidine-lyase activity(GO:0016842)
0.0 0.1 GO:0017060 3-galactosyl-N-acetylglucosaminide 4-alpha-L-fucosyltransferase activity(GO:0017060)
0.0 0.2 GO:0043495 protein anchor(GO:0043495)
0.0 0.1 GO:0047756 chondroitin 4-sulfotransferase activity(GO:0047756)
0.0 0.3 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.0 0.2 GO:0005131 growth hormone receptor binding(GO:0005131)
0.0 0.2 GO:0015925 galactosidase activity(GO:0015925)
0.0 0.2 GO:0008296 3'-5'-exodeoxyribonuclease activity(GO:0008296)
0.0 0.5 GO:0008175 tRNA methyltransferase activity(GO:0008175)
0.0 0.2 GO:0004127 cytidylate kinase activity(GO:0004127)
0.0 0.1 GO:0032296 ribonuclease III activity(GO:0004525) double-stranded RNA-specific ribonuclease activity(GO:0032296)
0.0 0.2 GO:0019788 NEDD8 transferase activity(GO:0019788)
0.0 0.1 GO:0004873 asialoglycoprotein receptor activity(GO:0004873)
0.0 0.3 GO:0070567 cytidylyltransferase activity(GO:0070567)
0.0 0.2 GO:0034235 GPI anchor binding(GO:0034235)
0.0 0.2 GO:0004972 NMDA glutamate receptor activity(GO:0004972)
0.0 0.1 GO:0015183 L-aspartate transmembrane transporter activity(GO:0015183)
0.0 0.2 GO:0033170 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.0 0.1 GO:0005338 nucleotide-sugar transmembrane transporter activity(GO:0005338)
0.0 0.1 GO:0046975 histone methyltransferase activity (H3-K36 specific)(GO:0046975)
0.0 0.2 GO:0004062 aryl sulfotransferase activity(GO:0004062)
0.0 1.4 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.0 0.1 GO:0004875 complement receptor activity(GO:0004875)
0.0 0.0 GO:0035014 phosphatidylinositol 3-kinase regulator activity(GO:0035014)
0.0 0.1 GO:0004814 arginine-tRNA ligase activity(GO:0004814)
0.0 0.6 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.0 0.3 GO:0005522 profilin binding(GO:0005522)
0.0 1.7 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.0 0.1 GO:0015379 potassium:chloride symporter activity(GO:0015379)
0.0 0.1 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.0 0.2 GO:0001727 lipid kinase activity(GO:0001727)
0.0 0.1 GO:0015252 hydrogen ion channel activity(GO:0015252)
0.0 0.1 GO:0000832 inositol hexakisphosphate kinase activity(GO:0000828) inositol hexakisphosphate 5-kinase activity(GO:0000832)
0.0 0.2 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.0 0.4 GO:0005031 tumor necrosis factor-activated receptor activity(GO:0005031)
0.0 0.0 GO:0004800 thyroxine 5'-deiodinase activity(GO:0004800)
0.0 0.2 GO:0051400 BH domain binding(GO:0051400)
0.0 0.1 GO:0003987 acetate-CoA ligase activity(GO:0003987)
0.0 0.1 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.0 0.3 GO:0050700 CARD domain binding(GO:0050700)
0.0 0.2 GO:0008440 inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440) inositol trisphosphate kinase activity(GO:0051766)
0.0 0.1 GO:0031628 opioid receptor binding(GO:0031628)
0.0 0.1 GO:0050815 phosphoserine binding(GO:0050815)
0.0 0.3 GO:0050431 transforming growth factor beta binding(GO:0050431)
0.0 0.2 GO:0050780 dopamine receptor binding(GO:0050780)
0.0 0.1 GO:0030306 ADP-ribosylation factor binding(GO:0030306)
0.0 0.1 GO:0008035 high-density lipoprotein particle binding(GO:0008035)
0.0 0.1 GO:0045569 TRAIL binding(GO:0045569)
0.0 0.3 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.0 0.2 GO:0042043 neurexin family protein binding(GO:0042043)
0.0 0.1 GO:0004563 beta-N-acetylhexosaminidase activity(GO:0004563)
0.0 0.1 GO:0003829 beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity(GO:0003829)
0.0 0.1 GO:0016308 1-phosphatidylinositol-4-phosphate 5-kinase activity(GO:0016308)
0.0 0.1 GO:0043208 glycosphingolipid binding(GO:0043208)
0.0 0.1 GO:0042808 obsolete neuronal Cdc2-like kinase binding(GO:0042808)
0.0 0.1 GO:0008853 exodeoxyribonuclease III activity(GO:0008853)
0.0 0.5 GO:0008484 sulfuric ester hydrolase activity(GO:0008484)
0.0 0.1 GO:0004308 exo-alpha-sialidase activity(GO:0004308) alpha-sialidase activity(GO:0016997)
0.0 0.1 GO:0004949 cannabinoid receptor activity(GO:0004949)
0.0 0.2 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.0 0.4 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.0 0.2 GO:0070410 co-SMAD binding(GO:0070410)
0.0 0.1 GO:0015184 L-cystine transmembrane transporter activity(GO:0015184)
0.0 0.2 GO:0004568 chitinase activity(GO:0004568)
0.0 0.1 GO:0004142 diacylglycerol cholinephosphotransferase activity(GO:0004142)
0.0 0.1 GO:0070579 methylcytosine dioxygenase activity(GO:0070579)
0.0 0.3 GO:0004526 ribonuclease P activity(GO:0004526)
0.0 0.4 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.0 0.4 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.0 0.0 GO:0034481 chondroitin sulfotransferase activity(GO:0034481)
0.0 0.1 GO:0070053 thrombospondin receptor activity(GO:0070053)
0.0 0.1 GO:0004300 enoyl-CoA hydratase activity(GO:0004300)
0.0 0.2 GO:0003993 acid phosphatase activity(GO:0003993)
0.0 0.1 GO:0048156 tau protein binding(GO:0048156)
0.0 0.1 GO:0005017 platelet-derived growth factor-activated receptor activity(GO:0005017)
0.0 0.3 GO:0004016 adenylate cyclase activity(GO:0004016)
0.0 0.1 GO:0033765 steroid dehydrogenase activity, acting on the CH-CH group of donors(GO:0033765)
0.0 0.1 GO:0001517 N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517)
0.0 0.2 GO:0048531 beta-1,3-galactosyltransferase activity(GO:0048531)
0.0 0.0 GO:0005527 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.0 0.2 GO:0051019 mitogen-activated protein kinase binding(GO:0051019)
0.0 0.4 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0 0.1 GO:0015194 L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.0 0.1 GO:0004457 lactate dehydrogenase activity(GO:0004457)
0.0 0.0 GO:0042799 histone methyltransferase activity (H4-K20 specific)(GO:0042799)
0.0 0.1 GO:0016413 O-acetyltransferase activity(GO:0016413)
0.0 0.0 GO:0005035 death receptor activity(GO:0005035)
0.0 0.1 GO:0032552 deoxyribonucleotide binding(GO:0032552)
0.0 0.1 GO:0052813 phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) phosphatidylinositol bisphosphate kinase activity(GO:0052813)
0.0 0.1 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.0 0.2 GO:0043425 bHLH transcription factor binding(GO:0043425)
0.0 0.1 GO:0005220 inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.0 0.3 GO:0060590 ATPase regulator activity(GO:0060590)
0.0 0.2 GO:0017049 GTP-Rho binding(GO:0017049)
0.0 0.1 GO:0008159 obsolete positive transcription elongation factor activity(GO:0008159)
0.0 0.1 GO:0050733 RS domain binding(GO:0050733)
0.0 0.1 GO:0042834 peptidoglycan binding(GO:0042834)
0.0 0.1 GO:0004449 isocitrate dehydrogenase (NAD+) activity(GO:0004449)
0.0 0.1 GO:0005315 inorganic phosphate transmembrane transporter activity(GO:0005315)
0.0 0.7 GO:0003755 peptidyl-prolyl cis-trans isomerase activity(GO:0003755)
0.0 0.1 GO:0031177 phosphopantetheine binding(GO:0031177)
0.0 0.4 GO:0008601 protein phosphatase type 2A regulator activity(GO:0008601)
0.0 0.1 GO:0004735 pyrroline-5-carboxylate reductase activity(GO:0004735)
0.0 0.1 GO:0008266 poly(U) RNA binding(GO:0008266)
0.0 0.1 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.0 0.1 GO:0015333 peptide:proton symporter activity(GO:0015333) proton-dependent peptide secondary active transmembrane transporter activity(GO:0022897)
0.0 0.3 GO:0043621 protein self-association(GO:0043621)
0.0 0.1 GO:0050786 RAGE receptor binding(GO:0050786)
0.0 0.3 GO:0004835 tubulin-tyrosine ligase activity(GO:0004835)
0.0 0.1 GO:0004616 phosphogluconate dehydrogenase (decarboxylating) activity(GO:0004616)
0.0 0.0 GO:0070492 oligosaccharide binding(GO:0070492)
0.0 0.1 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.0 0.1 GO:0031701 angiotensin receptor binding(GO:0031701)
0.0 0.1 GO:0016531 copper chaperone activity(GO:0016531)
0.0 0.3 GO:0030159 receptor signaling complex scaffold activity(GO:0030159)
0.0 0.2 GO:0015248 sterol transporter activity(GO:0015248)
0.0 0.1 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.0 1.1 GO:0042393 histone binding(GO:0042393)
0.0 0.1 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
0.0 0.0 GO:0042156 obsolete zinc-mediated transcriptional activator activity(GO:0042156)
0.0 0.1 GO:0005250 A-type (transient outward) potassium channel activity(GO:0005250)
0.0 0.0 GO:0016530 metallochaperone activity(GO:0016530)
0.0 0.1 GO:0003857 3-hydroxyacyl-CoA dehydrogenase activity(GO:0003857)
0.0 0.1 GO:0055077 gap junction hemi-channel activity(GO:0055077)
0.0 0.1 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.0 0.1 GO:0030368 interleukin-17 receptor activity(GO:0030368)
0.0 0.2 GO:0003906 DNA-(apurinic or apyrimidinic site) lyase activity(GO:0003906)
0.0 0.1 GO:0004994 somatostatin receptor activity(GO:0004994)
0.0 0.1 GO:0008409 5'-3' exonuclease activity(GO:0008409)
0.0 0.4 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.0 0.2 GO:0016891 endoribonuclease activity, producing 5'-phosphomonoesters(GO:0016891)
0.0 0.1 GO:0017110 nucleoside-diphosphatase activity(GO:0017110)
0.0 0.1 GO:0033612 receptor serine/threonine kinase binding(GO:0033612)
0.0 0.1 GO:0046404 ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity(GO:0046404) polydeoxyribonucleotide kinase activity(GO:0051733) ATP-dependent polynucleotide kinase activity(GO:0051734)
0.0 0.1 GO:0032452 histone demethylase activity(GO:0032452)
0.0 0.1 GO:0004703 G-protein coupled receptor kinase activity(GO:0004703)
0.0 0.0 GO:0004582 dolichyl-phosphate beta-D-mannosyltransferase activity(GO:0004582)
0.0 0.3 GO:0005484 SNAP receptor activity(GO:0005484)
0.0 0.1 GO:0016494 C-X-C chemokine receptor activity(GO:0016494)
0.0 0.1 GO:0015271 outward rectifier potassium channel activity(GO:0015271)
0.0 0.0 GO:0016941 natriuretic peptide receptor activity(GO:0016941)
0.0 0.1 GO:0003706 obsolete ligand-regulated transcription factor activity(GO:0003706)
0.0 0.0 GO:0000400 four-way junction DNA binding(GO:0000400)
0.0 0.0 GO:0010521 telomerase inhibitor activity(GO:0010521)
0.0 0.1 GO:0008649 rRNA methyltransferase activity(GO:0008649)
0.0 0.0 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.0 0.2 GO:0030742 GTP-dependent protein binding(GO:0030742)
0.0 0.1 GO:0004415 hyalurononglucosaminidase activity(GO:0004415)
0.0 0.2 GO:0051537 2 iron, 2 sulfur cluster binding(GO:0051537)
0.0 0.1 GO:0071813 lipoprotein particle binding(GO:0071813) protein-lipid complex binding(GO:0071814)
0.0 0.1 GO:0070087 chromo shadow domain binding(GO:0070087)
0.0 0.1 GO:0019136 deoxynucleoside kinase activity(GO:0019136)
0.0 0.3 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.0 0.1 GO:0016175 superoxide-generating NADPH oxidase activity(GO:0016175)
0.0 0.1 GO:0008430 selenium binding(GO:0008430)
0.0 0.0 GO:0008332 low voltage-gated calcium channel activity(GO:0008332)
0.0 0.1 GO:0008432 JUN kinase binding(GO:0008432)
0.0 0.0 GO:0090482 vitamin transmembrane transporter activity(GO:0090482)
0.0 0.1 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.0 0.1 GO:0042800 histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.0 0.1 GO:0004602 glutathione peroxidase activity(GO:0004602)
0.0 0.0 GO:0052658 inositol-1,4,5-trisphosphate 5-phosphatase activity(GO:0052658) inositol-1,3,4,5-tetrakisphosphate 5-phosphatase activity(GO:0052659)
0.0 0.1 GO:0015232 heme transporter activity(GO:0015232)
0.0 0.0 GO:0030899 calcium-dependent ATPase activity(GO:0030899)
0.0 0.1 GO:0004064 arylesterase activity(GO:0004064)
0.0 0.1 GO:0004974 leukotriene receptor activity(GO:0004974)
0.0 0.1 GO:0017153 sodium:dicarboxylate symporter activity(GO:0017153)
0.0 0.0 GO:0004301 epoxide hydrolase activity(GO:0004301)
0.0 0.0 GO:0042806 fucose binding(GO:0042806)
0.0 0.1 GO:0015321 sodium-dependent phosphate transmembrane transporter activity(GO:0015321)
0.0 0.0 GO:0071208 histone pre-mRNA DCP binding(GO:0071208)
0.0 0.1 GO:0004957 prostaglandin E receptor activity(GO:0004957)
0.0 0.1 GO:0030229 very-low-density lipoprotein particle receptor activity(GO:0030229)
0.0 0.0 GO:0015254 glycerol channel activity(GO:0015254)
0.0 0.0 GO:0004719 protein-L-isoaspartate (D-aspartate) O-methyltransferase activity(GO:0004719)
0.0 0.4 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.0 0.2 GO:0005344 oxygen transporter activity(GO:0005344)
0.0 0.1 GO:0008536 Ran GTPase binding(GO:0008536)
0.0 0.0 GO:0004311 farnesyltranstransferase activity(GO:0004311)
0.0 0.0 GO:0004517 nitric-oxide synthase activity(GO:0004517)
0.0 0.1 GO:0004047 aminomethyltransferase activity(GO:0004047)
0.0 0.1 GO:0004305 ethanolamine kinase activity(GO:0004305)
0.0 0.0 GO:0030375 thyroid hormone receptor coactivator activity(GO:0030375)
0.0 0.1 GO:0042166 acetylcholine binding(GO:0042166)
0.0 0.0 GO:0004476 mannose-6-phosphate isomerase activity(GO:0004476)
0.0 0.0 GO:0004045 aminoacyl-tRNA hydrolase activity(GO:0004045)
0.0 0.1 GO:0016783 sulfurtransferase activity(GO:0016783)
0.0 0.1 GO:0031996 thioesterase binding(GO:0031996)
0.0 0.0 GO:0051379 alpha2-adrenergic receptor activity(GO:0004938) epinephrine binding(GO:0051379)
0.0 0.1 GO:0015278 calcium-release channel activity(GO:0015278) ligand-gated calcium channel activity(GO:0099604)
0.0 0.1 GO:0080031 methyl indole-3-acetate esterase activity(GO:0080030) methyl salicylate esterase activity(GO:0080031) methyl jasmonate esterase activity(GO:0080032)
0.0 0.4 GO:0004177 aminopeptidase activity(GO:0004177)
0.0 0.0 GO:0004849 uridine kinase activity(GO:0004849)
0.0 0.0 GO:0032139 dinucleotide insertion or deletion binding(GO:0032139)
0.0 0.0 GO:0004500 dopamine beta-monooxygenase activity(GO:0004500)
0.0 0.1 GO:0004427 inorganic diphosphatase activity(GO:0004427)
0.0 0.2 GO:0003730 mRNA 3'-UTR binding(GO:0003730)
0.0 0.2 GO:0009881 photoreceptor activity(GO:0009881)
0.0 0.0 GO:0000064 L-ornithine transmembrane transporter activity(GO:0000064)
0.0 0.0 GO:0032794 GTPase activating protein binding(GO:0032794)
0.0 0.0 GO:0004966 galanin receptor activity(GO:0004966)
0.0 0.1 GO:0008171 O-methyltransferase activity(GO:0008171)
0.0 0.1 GO:0004652 polynucleotide adenylyltransferase activity(GO:0004652)
0.0 0.8 GO:0004553 hydrolase activity, hydrolyzing O-glycosyl compounds(GO:0004553)
0.0 0.0 GO:0008073 ornithine decarboxylase inhibitor activity(GO:0008073)
0.0 0.1 GO:0001619 obsolete lysosphingolipid and lysophosphatidic acid receptor activity(GO:0001619)
0.0 0.0 GO:0008821 crossover junction endodeoxyribonuclease activity(GO:0008821)
0.0 0.1 GO:0019864 IgG binding(GO:0019864)
0.0 0.2 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.0 1.0 GO:0017124 SH3 domain binding(GO:0017124)
0.0 0.1 GO:0045502 dynein binding(GO:0045502)
0.0 0.0 GO:0047184 1-acylglycerophosphocholine O-acyltransferase activity(GO:0047184)
0.0 0.0 GO:0030544 Hsp70 protein binding(GO:0030544)
0.0 0.4 GO:0003707 steroid hormone receptor activity(GO:0003707)
0.0 0.1 GO:0003840 gamma-glutamyltransferase activity(GO:0003840)
0.0 0.1 GO:0046974 histone methyltransferase activity (H3-K9 specific)(GO:0046974)
0.0 0.1 GO:0032393 MHC class I receptor activity(GO:0032393)
0.0 0.3 GO:0051087 chaperone binding(GO:0051087)
0.0 0.1 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.0 0.1 GO:0005041 low-density lipoprotein receptor activity(GO:0005041)
0.0 0.0 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.0 0.0 GO:0005275 amine transmembrane transporter activity(GO:0005275)
0.0 0.1 GO:0004889 acetylcholine-activated cation-selective channel activity(GO:0004889)
0.0 0.1 GO:0004749 ribose phosphate diphosphokinase activity(GO:0004749)
0.0 0.0 GO:0016361 activin receptor activity, type I(GO:0016361)
0.0 0.1 GO:0008641 small protein activating enzyme activity(GO:0008641)
0.0 0.1 GO:0004983 neuropeptide Y receptor activity(GO:0004983)
0.0 0.0 GO:0016803 ether hydrolase activity(GO:0016803)
0.0 0.0 GO:0047499 calcium-independent phospholipase A2 activity(GO:0047499)
0.0 0.0 GO:0001758 retinal dehydrogenase activity(GO:0001758)
0.0 0.0 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
0.0 0.0 GO:0019166 trans-2-enoyl-CoA reductase (NADPH) activity(GO:0019166)
0.0 0.1 GO:0005537 mannose binding(GO:0005537)
0.0 0.2 GO:0015035 protein disulfide oxidoreductase activity(GO:0015035)
0.0 0.3 GO:0001104 RNA polymerase II transcription cofactor activity(GO:0001104)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.2 PID TCR JNK PATHWAY JNK signaling in the CD4+ TCR pathway
0.1 0.2 PID HDAC CLASSII PATHWAY Signaling events mediated by HDAC Class II
0.1 0.7 SA PTEN PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.0 2.2 PID PI3KCI PATHWAY Class I PI3K signaling events
0.0 0.3 PID IL8 CXCR1 PATHWAY IL8- and CXCR1-mediated signaling events
0.0 0.4 PID IL8 CXCR2 PATHWAY IL8- and CXCR2-mediated signaling events
0.0 0.3 PID TCR RAS PATHWAY Ras signaling in the CD4+ TCR pathway
0.0 1.0 PID BCR 5PATHWAY BCR signaling pathway
0.0 0.3 ST PAC1 RECEPTOR PATHWAY PAC1 Receptor Pathway
0.0 0.7 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.0 1.4 PID TCR PATHWAY TCR signaling in naïve CD4+ T cells
0.0 1.2 PID THROMBIN PAR1 PATHWAY PAR1-mediated thrombin signaling events
0.0 0.1 PID P38 ALPHA BETA PATHWAY Regulation of p38-alpha and p38-beta
0.0 0.4 SA G1 AND S PHASES Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition.
0.0 0.3 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.0 0.3 ST JAK STAT PATHWAY Jak-STAT Pathway
0.0 0.5 PID CXCR3 PATHWAY CXCR3-mediated signaling events
0.0 0.3 PID LPA4 PATHWAY LPA4-mediated signaling events
0.0 0.9 PID LKB1 PATHWAY LKB1 signaling events
0.0 0.5 PID FAS PATHWAY FAS (CD95) signaling pathway
0.0 0.1 PID IL2 1PATHWAY IL2-mediated signaling events
0.0 0.3 PID CD40 PATHWAY CD40/CD40L signaling
0.0 0.4 PID REELIN PATHWAY Reelin signaling pathway
0.0 0.1 PID CD8 TCR PATHWAY TCR signaling in naïve CD8+ T cells
0.0 0.4 PID IL2 STAT5 PATHWAY IL2 signaling events mediated by STAT5
0.0 0.3 PID ALPHA SYNUCLEIN PATHWAY Alpha-synuclein signaling
0.0 0.6 PID HIF2PATHWAY HIF-2-alpha transcription factor network
0.0 0.9 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 0.1 PID EPO PATHWAY EPO signaling pathway
0.0 0.4 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.0 0.0 PID S1P S1P4 PATHWAY S1P4 pathway
0.0 0.1 PID IL2 PI3K PATHWAY IL2 signaling events mediated by PI3K
0.0 0.1 PID RANBP2 PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.0 0.1 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
0.0 0.2 PID GMCSF PATHWAY GMCSF-mediated signaling events
0.0 0.6 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0 0.3 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0 0.1 PID TRAIL PATHWAY TRAIL signaling pathway
0.0 0.3 PID KIT PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
0.0 0.0 ST TUMOR NECROSIS FACTOR PATHWAY Tumor Necrosis Factor Pathway.
0.0 0.3 SIG PIP3 SIGNALING IN B LYMPHOCYTES Genes related to PIP3 signaling in B lymphocytes
0.0 0.2 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0 0.1 PID S1P S1P1 PATHWAY S1P1 pathway
0.0 0.2 PID ERBB1 DOWNSTREAM PATHWAY ErbB1 downstream signaling
0.0 0.3 PID WNT CANONICAL PATHWAY Canonical Wnt signaling pathway
0.0 0.3 PID MYC PATHWAY C-MYC pathway
0.0 0.3 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.0 0.4 PID ERBB1 INTERNALIZATION PATHWAY Internalization of ErbB1
0.0 0.7 PID E2F PATHWAY E2F transcription factor network
0.0 0.0 PID EPHA2 FWD PATHWAY EPHA2 forward signaling
0.0 0.3 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.0 0.7 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression
0.0 0.0 PID PDGFRA PATHWAY PDGFR-alpha signaling pathway
0.0 0.1 PID NFKAPPAB CANONICAL PATHWAY Canonical NF-kappaB pathway
0.0 0.2 PID ENDOTHELIN PATHWAY Endothelins
0.0 0.0 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.0 0.2 PID FCER1 PATHWAY Fc-epsilon receptor I signaling in mast cells
0.0 0.1 ST IL 13 PATHWAY Interleukin 13 (IL-13) Pathway
0.0 0.1 PID MAPK TRK PATHWAY Trk receptor signaling mediated by the MAPK pathway
0.0 0.4 PID AURORA B PATHWAY Aurora B signaling
0.0 0.5 PID PDGFRB PATHWAY PDGFR-beta signaling pathway
0.0 0.3 PID ATR PATHWAY ATR signaling pathway
0.0 0.1 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.0 0.0 ST TYPE I INTERFERON PATHWAY Type I Interferon (alpha/beta IFN) Pathway
0.0 0.1 PID MET PATHWAY Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)
0.0 0.1 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.0 0.1 PID RHOA PATHWAY RhoA signaling pathway
0.0 0.1 PID AVB3 OPN PATHWAY Osteopontin-mediated events
0.0 0.0 ST GAQ PATHWAY G alpha q Pathway
0.0 0.0 PID SYNDECAN 4 PATHWAY Syndecan-4-mediated signaling events
0.0 0.1 PID ERBB2 ERBB3 PATHWAY ErbB2/ErbB3 signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 0.5 REACTOME G ALPHA1213 SIGNALLING EVENTS Genes involved in G alpha (12/13) signalling events
0.1 0.1 REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.1 1.9 REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.1 0.3 REACTOME REGULATION OF SIGNALING BY CBL Genes involved in Regulation of signaling by CBL
0.1 0.5 REACTOME ENDOSOMAL VACUOLAR PATHWAY Genes involved in Endosomal/Vacuolar pathway
0.1 1.3 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.1 0.6 REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.0 0.4 REACTOME REGULATION OF KIT SIGNALING Genes involved in Regulation of KIT signaling
0.0 0.9 REACTOME CD28 CO STIMULATION Genes involved in CD28 co-stimulation
0.0 0.4 REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT Genes involved in Organic cation/anion/zwitterion transport
0.0 0.1 REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.0 0.4 REACTOME CDC6 ASSOCIATION WITH THE ORC ORIGIN COMPLEX Genes involved in CDC6 association with the ORC:origin complex
0.0 0.3 REACTOME COSTIMULATION BY THE CD28 FAMILY Genes involved in Costimulation by the CD28 family
0.0 0.3 REACTOME ABACAVIR TRANSPORT AND METABOLISM Genes involved in Abacavir transport and metabolism
0.0 0.2 REACTOME DAG AND IP3 SIGNALING Genes involved in DAG and IP3 signaling
0.0 0.4 REACTOME CHONDROITIN SULFATE BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
0.0 0.3 REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY Genes involved in Adenylate cyclase activating pathway
0.0 0.3 REACTOME CTLA4 INHIBITORY SIGNALING Genes involved in CTLA4 inhibitory signaling
0.0 0.5 REACTOME NUCLEOTIDE LIKE PURINERGIC RECEPTORS Genes involved in Nucleotide-like (purinergic) receptors
0.0 0.3 REACTOME ALPHA LINOLENIC ACID ALA METABOLISM Genes involved in alpha-linolenic acid (ALA) metabolism
0.0 0.2 REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX UPON TLR7 8 OR 9 STIMULATION Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
0.0 0.2 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
0.0 0.7 REACTOME INTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Intrinsic Pathway for Apoptosis
0.0 0.7 REACTOME G1 PHASE Genes involved in G1 Phase
0.0 0.0 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.0 1.0 REACTOME GLYCOSPHINGOLIPID METABOLISM Genes involved in Glycosphingolipid metabolism
0.0 0.6 REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE Genes involved in Synthesis of PIPs at the plasma membrane
0.0 0.4 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.0 0.1 REACTOME BINDING AND ENTRY OF HIV VIRION Genes involved in Binding and entry of HIV virion
0.0 0.3 REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.0 0.2 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.0 0.1 REACTOME LYSOSOME VESICLE BIOGENESIS Genes involved in Lysosome Vesicle Biogenesis
0.0 0.3 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.0 0.2 REACTOME ACTIVATION OF ATR IN RESPONSE TO REPLICATION STRESS Genes involved in Activation of ATR in response to replication stress
0.0 0.2 REACTOME TRAF6 MEDIATED NFKB ACTIVATION Genes involved in TRAF6 mediated NF-kB activation
0.0 0.3 REACTOME REPAIR SYNTHESIS FOR GAP FILLING BY DNA POL IN TC NER Genes involved in Repair synthesis for gap-filling by DNA polymerase in TC-NER
0.0 0.4 REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 2 PROMOTER Genes involved in RNA Polymerase III Transcription Initiation From Type 2 Promoter
0.0 0.4 REACTOME GENERATION OF SECOND MESSENGER MOLECULES Genes involved in Generation of second messenger molecules
0.0 0.0 REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.0 0.1 REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY Genes involved in Regulation of the Fanconi anemia pathway
0.0 0.4 REACTOME IL RECEPTOR SHC SIGNALING Genes involved in Interleukin receptor SHC signaling
0.0 0.7 REACTOME G ALPHA Z SIGNALLING EVENTS Genes involved in G alpha (z) signalling events
0.0 0.0 REACTOME PLATELET HOMEOSTASIS Genes involved in Platelet homeostasis
0.0 0.2 REACTOME PIP3 ACTIVATES AKT SIGNALING Genes involved in PIP3 activates AKT signaling
0.0 0.3 REACTOME EXTENSION OF TELOMERES Genes involved in Extension of Telomeres
0.0 1.6 REACTOME RESPIRATORY ELECTRON TRANSPORT ATP SYNTHESIS BY CHEMIOSMOTIC COUPLING AND HEAT PRODUCTION BY UNCOUPLING PROTEINS Genes involved in Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins.
0.0 0.0 REACTOME CELL DEATH SIGNALLING VIA NRAGE NRIF AND NADE Genes involved in Cell death signalling via NRAGE, NRIF and NADE
0.0 0.0 REACTOME ASSOCIATION OF LICENSING FACTORS WITH THE PRE REPLICATIVE COMPLEX Genes involved in Association of licensing factors with the pre-replicative complex
0.0 0.2 REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR Genes involved in Trafficking and processing of endosomal TLR
0.0 1.0 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.0 0.3 REACTOME ELONGATION ARREST AND RECOVERY Genes involved in Elongation arrest and recovery
0.0 0.3 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.0 0.8 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0 0.1 REACTOME INNATE IMMUNE SYSTEM Genes involved in Innate Immune System
0.0 0.1 REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.0 0.3 REACTOME THE ROLE OF NEF IN HIV1 REPLICATION AND DISEASE PATHOGENESIS Genes involved in The role of Nef in HIV-1 replication and disease pathogenesis
0.0 0.0 REACTOME SIGNALING BY ACTIVATED POINT MUTANTS OF FGFR1 Genes involved in Signaling by activated point mutants of FGFR1
0.0 0.3 REACTOME RNA POL I TRANSCRIPTION INITIATION Genes involved in RNA Polymerase I Transcription Initiation
0.0 0.1 REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.0 0.2 REACTOME HIGHLY CALCIUM PERMEABLE POSTSYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Highly calcium permeable postsynaptic nicotinic acetylcholine receptors
0.0 0.2 REACTOME G0 AND EARLY G1 Genes involved in G0 and Early G1
0.0 0.1 REACTOME PLATELET SENSITIZATION BY LDL Genes involved in Platelet sensitization by LDL
0.0 0.3 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.0 0.1 REACTOME SPRY REGULATION OF FGF SIGNALING Genes involved in Spry regulation of FGF signaling
0.0 0.1 REACTOME RAF MAP KINASE CASCADE Genes involved in RAF/MAP kinase cascade
0.0 0.2 REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION Genes involved in activated TAK1 mediates p38 MAPK activation
0.0 0.2 REACTOME THROMBIN SIGNALLING THROUGH PROTEINASE ACTIVATED RECEPTORS PARS Genes involved in Thrombin signalling through proteinase activated receptors (PARs)
0.0 0.2 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.0 0.3 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
0.0 0.3 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.0 0.2 REACTOME PYRUVATE METABOLISM Genes involved in Pyruvate metabolism
0.0 0.2 REACTOME REGULATORY RNA PATHWAYS Genes involved in Regulatory RNA pathways
0.0 0.2 REACTOME FGFR4 LIGAND BINDING AND ACTIVATION Genes involved in FGFR4 ligand binding and activation
0.0 0.1 REACTOME REGULATION OF WATER BALANCE BY RENAL AQUAPORINS Genes involved in Regulation of Water Balance by Renal Aquaporins
0.0 0.2 REACTOME TRANSPORT OF RIBONUCLEOPROTEINS INTO THE HOST NUCLEUS Genes involved in Transport of Ribonucleoproteins into the Host Nucleus
0.0 0.1 REACTOME CREB PHOSPHORYLATION THROUGH THE ACTIVATION OF CAMKII Genes involved in CREB phosphorylation through the activation of CaMKII
0.0 0.1 REACTOME REGULATION OF ORNITHINE DECARBOXYLASE ODC Genes involved in Regulation of ornithine decarboxylase (ODC)
0.0 1.0 REACTOME MITOTIC PROMETAPHASE Genes involved in Mitotic Prometaphase
0.0 0.5 REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
0.0 0.1 REACTOME REGULATION OF IFNG SIGNALING Genes involved in Regulation of IFNG signaling
0.0 0.2 REACTOME RECYCLING PATHWAY OF L1 Genes involved in Recycling pathway of L1
0.0 0.1 REACTOME KERATAN SULFATE BIOSYNTHESIS Genes involved in Keratan sulfate biosynthesis
0.0 0.0 REACTOME APC C CDH1 MEDIATED DEGRADATION OF CDC20 AND OTHER APC C CDH1 TARGETED PROTEINS IN LATE MITOSIS EARLY G1 Genes involved in APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1
0.0 0.3 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.0 0.2 REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.0 0.6 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.0 0.1 REACTOME RAP1 SIGNALLING Genes involved in Rap1 signalling
0.0 0.1 REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS Genes involved in Membrane binding and targetting of GAG proteins
0.0 0.7 REACTOME DNA REPLICATION Genes involved in DNA Replication
0.0 0.1 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.0 0.1 REACTOME RIP MEDIATED NFKB ACTIVATION VIA DAI Genes involved in RIP-mediated NFkB activation via DAI
0.0 0.0 REACTOME SHC MEDIATED SIGNALLING Genes involved in SHC-mediated signalling
0.0 0.4 REACTOME AMINE LIGAND BINDING RECEPTORS Genes involved in Amine ligand-binding receptors
0.0 0.1 REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.0 0.3 REACTOME POST TRANSLATIONAL MODIFICATION SYNTHESIS OF GPI ANCHORED PROTEINS Genes involved in Post-translational modification: synthesis of GPI-anchored proteins