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ENCODE: H3K4me1 ChIP-Seq of primary human cells
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CREMA is a free online tool that recognizes most important transcription factors that change the chromatin state across different samples.

Results for NR1I3

Z-value: 0.70

Motif logo

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Transcription factors associated with NR1I3

Gene Symbol Gene ID Gene Info
NR1I3
ENSG00000143257.7 NR1I3

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE Gene Distance Association probability Pearson corr. coef. P-value Plot
NR1I3chr1_161211637_16121202337380.0942040.147.2e-01Click!

Activity of the NR1I3 motif across conditions

Conditions sorted by the z-value of the NR1I3 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE) Target Score Top associated gene Gene Info Distance of CRE to TSS CRE/Gene association probability
chr3_112178819_112179007 0.34 BTLA
 B and T lymphocyte associated
 39292
 0.17
chr5_67530096_67530377 0.28 PIK3R1
 phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
 5490
 0.28
chr17_54679747_54680041 0.27 NOG
 noggin
 8834
 0.3
chr6_138137693_138137892 0.27 RP11-356I2.4
9239
 0.22
chr7_128777785_128778040 0.26 TSPAN33
 tetraspanin 33
 6800
 0.16
chr6_6593122_6593282 0.26 LY86
 lymphocyte antigen 86
 4300
 0.27
chr2_29233309_29233475 0.26 FAM179A
 family with sequence similarity 179, member A
 7735
 0.16
chr16_47515766_47515917 0.25 ITFG1
 integrin alpha FG-GAP repeat containing 1
 17781
 0.15
chr1_169662886_169663277 0.25 SELL
 selectin L
 17758
 0.18
chr7_24267550_24267736 0.24 AC004485.3
27695
 0.18
chr19_39819527_39819875 0.24 GMFG
 glia maturation factor, gamma
 6944
 0.09
chr1_65423839_65424016 0.24 JAK1
 Janus kinase 1
 8260
 0.25
chr2_45478028_45478179 0.23 SIX2
 SIX homeobox 2
 241534
 0.02
chr2_135049910_135050099 0.23 MGAT5
 mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase
 38174
 0.2
chr22_23482336_23482675 0.22 RTDR1
 rhabdoid tumor deletion region gene 1
 18
 0.96
chr10_134368978_134369207 0.22 INPP5A
 inositol polyphosphate-5-phosphatase, 40kDa
 17449
 0.21
chr8_8735555_8735713 0.22 MFHAS1
 malignant fibrous histiocytoma amplified sequence 1
 15521
 0.19
chr2_20094815_20094966 0.22 TTC32
 tetratricopeptide repeat domain 32
 6512
 0.26
chr1_46008468_46008619 0.22 AKR1A1
 aldo-keto reductase family 1, member A1 (aldehyde reductase)
 7672
 0.14
chr16_27462069_27462270 0.22 IL21R-AS1
 IL21R antisense RNA 1
 2545
 0.28
chr19_5130688_5131043 0.22 CTC-482H14.5
47265
 0.14
chr10_4022036_4022300 0.22 KLF6
 Kruppel-like factor 6
 194695
 0.03
chr10_48460684_48460835 0.21 GDF10
 growth differentiation factor 10
 21783
 0.18
chr13_113806578_113806884 0.21 PROZ
 protein Z, vitamin K-dependent plasma glycoprotein
 6237
 0.13
chr2_16106193_16106413 0.21 ENSG00000243541
 .
 15200
 0.18
chr20_2722250_2722401 0.21 EBF4
 early B-cell factor 4
 35438
 0.09
chr2_242881769_242881920 0.21 AC131097.3
5857
 0.19
chr15_60848077_60848282 0.20 CTD-2501E16.2
26007
 0.16
chr3_190414491_190414848 0.20 ENSG00000223117
 .
 54717
 0.15
chr8_121762007_121762212 0.20 RP11-713M15.1
11384
 0.25
chr13_30041218_30041369 0.20 MTUS2-AS1
 MTUS2 antisense RNA 1
 20361
 0.23
chr3_15501836_15502208 0.20 EAF1-AS1
 EAF1 antisense RNA 1
 8913
 0.12
chr12_122027698_122027887 0.20 KDM2B
 lysine (K)-specific demethylase 2B
 8872
 0.18
chr9_130738343_130738494 0.20 FAM102A
 family with sequence similarity 102, member A
 4374
 0.13
chr10_7029346_7029497 0.20 PRKCQ
 protein kinase C, theta
 407158
 0.01
chr20_57723964_57724434 0.20 ZNF831
 zinc finger protein 831
 41876
 0.16
chr6_156955714_156956050 0.20 ARID1B
 AT rich interactive domain 1B (SWI1-like)
 143181
 0.05
chr2_175486588_175486745 0.19 WIPF1
 WAS/WASL interacting protein family, member 1
 12641
 0.2
chr2_58136289_58136440 0.19 VRK2
 vaccinia related kinase 2
 1578
 0.56
chr14_91502758_91502909 0.19 RPS6KA5
 ribosomal protein S6 kinase, 90kDa, polypeptide 5
 23645
 0.17
chrX_1600320_1600585 0.19 ASMTL
 acetylserotonin O-methyltransferase-like
 27797
 0.16
chr14_35303784_35304022 0.19 ENSG00000251726
 .
 10663
 0.17
chrY_1550321_1550585 0.19 NA
 NA
 > 106
 NA
chr2_197009997_197010148 0.19 RP11-347P5.1
5915
 0.22
chr1_27959886_27960101 0.19 FGR
 feline Gardner-Rasheed sarcoma viral oncogene homolog
 1734
 0.27
chr3_101832900_101833053 0.19 ZPLD1
 zona pellucida-like domain containing 1
 14888
 0.29
chr17_56456680_56457108 0.19 RNF43
 ring finger protein 43
 23188
 0.11
chr17_14096680_14097352 0.19 ENSG00000252305
 .
 16568
 0.19
chr7_127054523_127055019 0.18 ZNF800
 zinc finger protein 800
 17207
 0.24
chr14_97586844_97587256 0.18 VRK1
 vaccinia related kinase 1
 244684
 0.02
chr2_69000085_69000318 0.18 ARHGAP25
 Rho GTPase activating protein 25
 1732
 0.44
chr2_38810640_38810791 0.18 HNRNPLL
 heterogeneous nuclear ribonucleoprotein L-like
 13737
 0.19
chr10_12631284_12631499 0.18 ENSG00000263584
 .
 10639
 0.27
chr5_55884311_55884521 0.18 AC022431.2
 Homo sapiens uncharacterized LOC101928448 (LOC101928448), mRNA.
 17643
 0.22
chr17_47809986_47810367 0.18 FAM117A
 family with sequence similarity 117, member A
 8287
 0.15
chr13_100071950_100072184 0.18 ENSG00000266207
 .
 33656
 0.15
chr11_59535226_59535396 0.18 STX3
 syntaxin 3
 12386
 0.14
chr6_99938862_99939169 0.18 USP45
 ubiquitin specific peptidase 45
 8274
 0.18
chrX_1602588_1602855 0.18 ASMTL
 acetylserotonin O-methyltransferase-like
 30066
 0.16
chr19_50073795_50074168 0.18 ENSG00000207073
 .
 4052
 0.08
chr15_29240397_29240548 0.18 APBA2
 amyloid beta (A4) precursor protein-binding, family A, member 2
 13035
 0.23
chr17_45297370_45297652 0.18 MYL4
 myosin, light chain 4, alkali; atrial, embryonic
 115
 0.84
chrX_78416040_78416499 0.18 GPR174
 G protein-coupled receptor 174
 10200
 0.32
chr20_37505321_37505472 0.18 ENSG00000240474
 .
 3983
 0.24
chr1_89595445_89595689 0.18 GBP2
 guanylate binding protein 2, interferon-inducible
 3770
 0.23
chr4_148925524_148925723 0.17 ARHGAP10
 Rho GTPase activating protein 10
 122605
 0.06
chr3_44484489_44484640 0.17 ZNF445
 zinc finger protein 445
 34598
 0.14
chr6_111443474_111443841 0.17 ENSG00000200926
 .
 31122
 0.16
chr3_196336038_196336189 0.17 LINC01063
 long intergenic non-protein coding RNA 1063
 23345
 0.11
chrX_78418820_78418971 0.17 GPR174
 G protein-coupled receptor 174
 7574
 0.33
chr11_13314702_13314853 0.17 ARNTL
 aryl hydrocarbon receptor nuclear translocator-like
 15345
 0.25
chr7_50364490_50364641 0.17 IKZF1
 IKAROS family zinc finger 1 (Ikaros)
 2680
 0.39
chr14_22890396_22890547 0.17 ENSG00000251002
 .
 11248
 0.12
chr1_160715023_160715174 0.17 SLAMF7
 SLAM family member 7
 6004
 0.18
chr4_113209820_113210146 0.17 TIFA
 TRAF-interacting protein with forkhead-associated domain
 2924
 0.21
chr1_168482288_168482558 0.17 XCL2
 chemokine (C motif) ligand 2
 30812
 0.2
chr3_23483889_23484071 0.17 ENSG00000265645
 .
 38089
 0.18
chr1_110165621_110165808 0.17 AMPD2
 adenosine monophosphate deaminase 2
 722
 0.46
chr7_142941436_142941642 0.17 GSTK1
 glutathione S-transferase kappa 1
 353
 0.79
chr12_9144662_9144957 0.16 KLRG1
 killer cell lectin-like receptor subfamily G, member 1
 143
 0.95
chrY_1552539_1552862 0.16 NA
 NA
 > 106
 NA
chr5_14983835_14984240 0.16 ENSG00000212036
 .
 73288
 0.11
chr1_15483643_15483794 0.16 TMEM51
 transmembrane protein 51
 3433
 0.27
chr13_111188696_111188940 0.16 RAB20
 RAB20, member RAS oncogene family
 25262
 0.17
chr7_106165541_106165692 0.16 CTB-111H14.1
20331
 0.27
chr18_72702111_72702262 0.16 ZADH2
 zinc binding alcohol dehydrogenase domain containing 2
 215282
 0.02
chr3_175075659_175075810 0.16 ENSG00000264974
 .
 11595
 0.25
chr2_62430640_62430961 0.16 ENSG00000266097
 .
 2161
 0.29
chr3_127348995_127349623 0.16 PODXL2
 podocalyxin-like 2
 1285
 0.41
chr2_85085633_85085887 0.16 TRABD2A
 TraB domain containing 2A
 22446
 0.18
chr13_30725272_30725600 0.16 ENSG00000266816
 .
 55400
 0.16
chr17_56432340_56432491 0.16 SUPT4H1
 suppressor of Ty 4 homolog 1 (S. cerevisiae)
 1961
 0.22
chr8_119292042_119292193 0.16 AC023590.1
 Uncharacterized protein
 2364
 0.46
chr15_76141909_76142060 0.16 UBE2Q2
 ubiquitin-conjugating enzyme E2Q family member 2
 5599
 0.16
chr17_76779813_76780089 0.16 CYTH1
 cytohesin 1
 1572
 0.38
chr7_142001773_142001924 0.16 PRSS3P3
 protease, serine, 3 pseudogene 3
 12239
 0.22
chr12_9889248_9889774 0.16 CLECL1
 C-type lectin-like 1
 3616
 0.19
chr12_55355288_55355457 0.16 TESPA1
 thymocyte expressed, positive selection associated 1
 1109
 0.58
chr17_20156757_20156908 0.16 ENSG00000252971
 .
 36738
 0.14
chr8_8713745_8714044 0.16 MFHAS1
 malignant fibrous histiocytoma amplified sequence 1
 37261
 0.16
chr19_14279308_14279579 0.16 LPHN1
 latrophilin 1
 7095
 0.12
chr6_37017673_37017845 0.16 COX6A1P2
 cytochrome c oxidase subunit VIa polypeptide 1 pseudogene 2
 5152
 0.22
chr22_40621973_40622124 0.16 TNRC6B
 trinucleotide repeat containing 6B
 38959
 0.18
chr9_95786581_95786807 0.15 FGD3
 FYVE, RhoGEF and PH domain containing 3
 9352
 0.19
chr2_16105641_16106067 0.15 ENSG00000243541
 .
 14751
 0.18
chr8_59924469_59924620 0.15 RP11-328K2.1
19047
 0.25
chr10_123598584_123598735 0.15 ENSG00000201884
 .
 7456
 0.26
chr4_143492069_143492229 0.15 INPP4B
 inositol polyphosphate-4-phosphatase, type II, 105kDa
 10327
 0.33
chr9_33147549_33147791 0.15 RP11-326F20.5
19303
 0.14
chr14_35699557_35699724 0.15 PSMA6
 proteasome (prosome, macropain) subunit, alpha type, 6
 48199
 0.14
chr2_207396183_207396430 0.15 ADAM23
 ADAM metallopeptidase domain 23
 63253
 0.11
chr9_130787624_130787958 0.15 RP11-379C10.1
31850
 0.08
chr5_35826936_35827087 0.15 CTD-2113L7.1
109
 0.97
chr11_128541166_128541342 0.15 RP11-744N12.3
15069
 0.18
chr11_95434433_95434612 0.15 FAM76B
 family with sequence similarity 76, member B
 85447
 0.09
chr14_90009937_90010173 0.15 FOXN3-AS2
 FOXN3 antisense RNA 2
 32505
 0.14
chr2_112190871_112191169 0.15 ENSG00000266139
 .
 112352
 0.07
chr16_68116183_68116430 0.15 NFATC3
 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3
 2941
 0.15
chr2_25556807_25556990 0.15 ENSG00000221445
 .
 5308
 0.23
chr9_129159177_129159360 0.15 ENSG00000253079
 .
 11421
 0.2
chr3_45735930_45736127 0.15 SACM1L
 SAC1 suppressor of actin mutations 1-like (yeast)
 5077
 0.19
chrX_39195070_39195348 0.15 ENSG00000207122
 .
 254671
 0.02
chr1_50882030_50882181 0.15 DMRTA2
 DMRT-like family A2
 5199
 0.26
chr3_46411260_46411477 0.15 CCR5
 chemokine (C-C motif) receptor 5 (gene/pseudogene)
 265
 0.9
chr1_25308637_25308788 0.15 RUNX3
 runt-related transcription factor 3
 17211
 0.18
chr11_47417148_47417745 0.14 RP11-750H9.5
255
 0.83
chr3_13456823_13457198 0.14 NUP210
 nucleoporin 210kDa
 4799
 0.27
chr4_170745007_170745217 0.14 ENSG00000264713
 .
 38681
 0.18
chr2_235055184_235055371 0.14 SPP2
 secreted phosphoprotein 2, 24kDa
 95846
 0.08
chrX_65240625_65241043 0.14 ENSG00000207939
 .
 2122
 0.33
chr10_11214521_11214672 0.14 RP3-323N1.2
1257
 0.5
chr17_37930387_37930595 0.14 IKZF3
 IKAROS family zinc finger 3 (Aiolos)
 3987
 0.16
chr6_110711697_110711922 0.14 DDO
 D-aspartate oxidase
 24956
 0.16
chr2_135425836_135426057 0.14 TMEM163
 transmembrane protein 163
 50624
 0.17
chr3_66444911_66445177 0.14 ENSG00000241587
 .
 70765
 0.12
chr11_128478831_128478982 0.14 ETS1
 v-ets avian erythroblastosis virus E26 oncogene homolog 1
 21453
 0.21
chr8_129665336_129665520 0.14 ENSG00000221351
 .
 166612
 0.04
chr6_131605644_131605795 0.14 AKAP7
 A kinase (PRKA) anchor protein 7
 34149
 0.23
chr4_153007039_153007190 0.14 ENSG00000253077
 .
 114349
 0.06
chr7_142197913_142198064 0.14 MTRNR2L6
 MT-RNR2-like 6
 176116
 0.03
chr2_242712064_242712447 0.14 GAL3ST2
 galactose-3-O-sulfotransferase 2
 3985
 0.12
chrX_16612049_16612225 0.14 ENSG00000265144
 .
 33071
 0.16
chr1_186268373_186268524 0.14 PRG4
 proteoglycan 4
 3037
 0.25
chrX_131613764_131613952 0.14 MBNL3
 muscleblind-like splicing regulator 3
 9185
 0.29
chr12_122812012_122812295 0.14 CLIP1
 CAP-GLY domain containing linker protein 1
 36411
 0.15
chr17_33774331_33774488 0.14 SLFN13
 schlafen family member 13
 4
 0.97
chr2_203530973_203531252 0.14 FAM117B
 family with sequence similarity 117, member B
 31201
 0.23
chr11_117097868_117098019 0.14 PCSK7
 proprotein convertase subtilisin/kexin type 7
 3013
 0.18
chr20_62712580_62712905 0.14 OPRL1
 opiate receptor-like 1
 1193
 0.24
chr15_52022956_52023209 0.14 LYSMD2
 LysM, putative peptidoglycan-binding, domain containing 2
 7236
 0.14
chr12_89727726_89727877 0.14 DUSP6
 dual specificity phosphatase 6
 17147
 0.24
chr2_85050169_85050320 0.14 TRABD2A
 TraB domain containing 2A
 57962
 0.11
chr6_109357060_109357211 0.14 ENSG00000199944
 .
 23682
 0.16
chr10_8466384_8466535 0.14 ENSG00000212505
 .
 232335
 0.02
chr13_33514702_33514853 0.14 KL
 klotho
 75430
 0.11
chr3_186757183_186757348 0.14 ST6GAL1
 ST6 beta-galactosamide alpha-2,6-sialyltranferase 1
 4266
 0.28
chr7_101388868_101389019 0.14 CUX1
 cut-like homeobox 1
 70016
 0.11
chr17_39496485_39496762 0.14 KRT33A
 keratin 33A
 10441
 0.08
chr12_22691459_22691610 0.13 C2CD5
 C2 calcium-dependent domain containing 5
 5653
 0.3
chr1_121258953_121259201 0.13 FCGR1B
 Fc fragment of IgG, high affinity Ib, receptor (CD64)
 323140
 0.01
chr12_46629041_46629192 0.13 SLC38A1
 solute carrier family 38, member 1
 32368
 0.23
chr1_12149159_12149332 0.13 ENSG00000201135
 .
 11204
 0.15
chr7_104850801_104851099 0.13 SRPK2
 SRSF protein kinase 2
 58512
 0.12
chr20_37460991_37461142 0.13 PPP1R16B
 protein phosphatase 1, regulatory subunit 16B
 26699
 0.16
chr2_12417779_12417930 0.13 ENSG00000264089
 .
 78598
 0.11
chr14_91698344_91698868 0.13 CTD-2547L24.3
 HCG1816139; Uncharacterized protein
 10497
 0.16
chr1_45162405_45162569 0.13 C1orf228
 chromosome 1 open reading frame 228
 6981
 0.11
chr11_65319407_65320254 0.13 LTBP3
 latent transforming growth factor beta binding protein 3
 1368
 0.23
chr15_50389614_50389935 0.13 ATP8B4
 ATPase, class I, type 8B, member 4
 16927
 0.23
chr1_144360487_144360771 0.13 PPIAL4B
 peptidylprolyl isomerase A (cyclophilin A)-like 4B
 3617
 0.25
chr3_131104918_131105242 0.13 NUDT16
 nudix (nucleoside diphosphate linked moiety X)-type motif 16
 4451
 0.19
chr5_49929906_49930306 0.13 PARP8
 poly (ADP-ribose) polymerase family, member 8
 31627
 0.25
chr6_112060261_112060435 0.13 FYN
 FYN oncogene related to SRC, FGR, YES
 19083
 0.24
chr9_130768286_130768549 0.13 FAM102A
 family with sequence similarity 102, member A
 25625
 0.1
chr19_49594900_49595051 0.13 SNRNP70
 small nuclear ribonucleoprotein 70kDa (U1)
 5238
 0.07
chr20_57733456_57733718 0.13 ZNF831
 zinc finger protein 831
 32488
 0.19
chr11_102319316_102319512 0.13 TMEM123
 transmembrane protein 123
 769
 0.6
chr2_240139272_240139549 0.13 HDAC4
 histone deacetylase 4
 26658
 0.16
chr15_32653399_32653683 0.13 ENSG00000221444
 .
 32132
 0.1
chr2_39604885_39605036 0.13 MAP4K3
 mitogen-activated protein kinase kinase kinase kinase 3
 1990
 0.32
chr9_138372034_138372554 0.13 PPP1R26-AS1
 PPP1R26 antisense RNA 1
 270
 0.72
chr2_2689850_2690051 0.13 ENSG00000263570
 .
 331152
 0.01
chr1_192854593_192854744 0.13 ENSG00000223075
 .
 9553
 0.26
chr16_89362946_89363099 0.13 AC137932.5
894
 0.47
chr5_139035453_139035988 0.13 CXXC5
 CXXC finger protein 5
 3420
 0.27
chr1_100929192_100929425 0.13 RP5-837M10.4
22245
 0.2
chrX_48913511_48913662 0.13 CCDC120
 coiled-coil domain containing 120
 2485
 0.14
chr4_40195311_40195826 0.13 RHOH
 ras homolog family member H
 285
 0.92
chr9_35639292_35639607 0.13 RP11-331F9.3
3062
 0.1
chr14_35595819_35596045 0.13 KIAA0391
 KIAA0391
 3967
 0.23
chr19_51221635_51221873 0.13 SHANK1
 SH3 and multiple ankyrin repeat domains 1
 953
 0.4
chr2_42523029_42523463 0.13 EML4
 echinoderm microtubule associated protein like 4
 5147
 0.28
chr14_99691611_99691762 0.13 AL109767.1
37599
 0.16
chr4_39030218_39030369 0.13 TMEM156
 transmembrane protein 156
 3748
 0.25
chr2_32133230_32133428 0.13 ENSG00000221326
 .
 11689
 0.21
chr10_104338876_104339209 0.13 ENSG00000207029
 .
 12239
 0.15
chr6_152043719_152044019 0.13 ESR1
 estrogen receptor 1
 32238
 0.21
chrY_7598458_7598609 0.13 RFTN1P1
 raftlin, lipid raft linker 1 pseudogene 1
 46215
 0.21
chr8_100549940_100550091 0.13 ENSG00000216069
 .
 926
 0.39
chr11_30348563_30348857 0.13 ARL14EP
 ADP-ribosylation factor-like 14 effector protein
 873
 0.73

Histogram of CRE-TSS distances for CREs targeted by :

Histogram of

Rank distribution of CRE target scores:

Histogram of target CRE score.

Distribution of target CREs across different genomic regions:

Weighted Piechart of Weighted Piechart of Weighted Piechart of

Network of associatons between targets according to the STRING database.

StringDB image

First level regulatory network of NR1I3

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0046642 negative regulation of alpha-beta T cell proliferation(GO:0046642)
0.0 0.1 GO:0050862 positive regulation of T cell receptor signaling pathway(GO:0050862)
0.0 0.1 GO:1900121 regulation of receptor binding(GO:1900120) negative regulation of receptor binding(GO:1900121)
0.0 0.1 GO:0032237 activation of store-operated calcium channel activity(GO:0032237) regulation of store-operated calcium channel activity(GO:1901339) positive regulation of store-operated calcium channel activity(GO:1901341)
0.0 0.1 GO:0030210 heparin biosynthetic process(GO:0030210)
0.0 0.1 GO:0030186 melatonin metabolic process(GO:0030186) melatonin biosynthetic process(GO:0030187)
0.0 0.1 GO:0010867 positive regulation of triglyceride biosynthetic process(GO:0010867)
0.0 0.1 GO:0010459 negative regulation of heart rate(GO:0010459)
0.0 0.1 GO:0007343 egg activation(GO:0007343)
0.0 0.0 GO:0002513 tolerance induction to self antigen(GO:0002513)
0.0 0.1 GO:0032506 cytokinetic process(GO:0032506)
0.0 0.1 GO:0090116 DNA methylation on cytosine(GO:0032776) C-5 methylation of cytosine(GO:0090116)
0.0 0.1 GO:0003077 obsolete negative regulation of diuresis(GO:0003077)
0.0 0.1 GO:0006198 cAMP catabolic process(GO:0006198)
0.0 0.1 GO:0045722 positive regulation of gluconeogenesis(GO:0045722)
0.0 0.1 GO:0045591 positive regulation of regulatory T cell differentiation(GO:0045591)
0.0 0.0 GO:0045589 regulation of regulatory T cell differentiation(GO:0045589)
0.0 0.1 GO:0048742 regulation of skeletal muscle fiber development(GO:0048742)
0.0 0.1 GO:0061756 leukocyte tethering or rolling(GO:0050901) leukocyte adhesion to vascular endothelial cell(GO:0061756)
0.0 0.1 GO:0031665 negative regulation of lipopolysaccharide-mediated signaling pathway(GO:0031665)
0.0 0.1 GO:0033152 immunoglobulin V(D)J recombination(GO:0033152)
0.0 0.0 GO:0015801 aromatic amino acid transport(GO:0015801)
0.0 0.0 GO:0045341 MHC class I biosynthetic process(GO:0045341) regulation of MHC class I biosynthetic process(GO:0045343)
0.0 0.0 GO:0048289 isotype switching to IgE isotypes(GO:0048289) regulation of isotype switching to IgE isotypes(GO:0048293)
0.0 0.0 GO:0051409 response to nitrosative stress(GO:0051409)
0.0 0.2 GO:0019059 obsolete initiation of viral infection(GO:0019059)
0.0 0.1 GO:0007130 synaptonemal complex assembly(GO:0007130)
0.0 0.1 GO:0034755 iron ion transmembrane transport(GO:0034755)
0.0 0.1 GO:0000154 rRNA modification(GO:0000154)
0.0 0.1 GO:0046827 positive regulation of protein export from nucleus(GO:0046827)
0.0 0.1 GO:0021898 commitment of multipotent stem cells to neuronal lineage in forebrain(GO:0021898)
0.0 0.0 GO:0045425 positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process(GO:0045425)
0.0 0.1 GO:0032926 negative regulation of activin receptor signaling pathway(GO:0032926)
0.0 0.1 GO:0010508 positive regulation of autophagy(GO:0010508)
0.0 0.0 GO:0060394 negative regulation of pathway-restricted SMAD protein phosphorylation(GO:0060394)
0.0 0.1 GO:0003056 regulation of vascular smooth muscle contraction(GO:0003056)
0.0 0.1 GO:0042989 sequestering of actin monomers(GO:0042989)
0.0 0.1 GO:0017183 peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183)
0.0 0.0 GO:0009048 dosage compensation by inactivation of X chromosome(GO:0009048)
0.0 0.0 GO:0002313 mature B cell differentiation involved in immune response(GO:0002313)
0.0 0.1 GO:0000712 resolution of meiotic recombination intermediates(GO:0000712) meiotic chromosome separation(GO:0051307)
0.0 0.0 GO:0035268 protein mannosylation(GO:0035268) protein O-linked mannosylation(GO:0035269) mannosylation(GO:0097502)
0.0 0.0 GO:0034219 carbohydrate transmembrane transport(GO:0034219)
0.0 0.0 GO:0031580 membrane raft polarization(GO:0001766) membrane raft distribution(GO:0031580)
0.0 0.0 GO:0019852 L-ascorbic acid metabolic process(GO:0019852)
0.0 0.0 GO:0052251 induction by organism of defense response of other organism involved in symbiotic interaction(GO:0052251)
0.0 0.1 GO:0045793 positive regulation of cell size(GO:0045793)
0.0 0.0 GO:0001880 Mullerian duct regression(GO:0001880)
0.0 0.0 GO:0015705 iodide transport(GO:0015705)
0.0 0.0 GO:0031442 positive regulation of mRNA 3'-end processing(GO:0031442) positive regulation of mRNA processing(GO:0050685) positive regulation of mRNA metabolic process(GO:1903313)
0.0 0.0 GO:0006167 AMP biosynthetic process(GO:0006167)
0.0 0.1 GO:0016572 histone phosphorylation(GO:0016572)
0.0 0.0 GO:0010572 positive regulation of platelet activation(GO:0010572)
0.0 0.1 GO:2000193 regulation of icosanoid secretion(GO:0032303) positive regulation of icosanoid secretion(GO:0032305) regulation of prostaglandin secretion(GO:0032306) positive regulation of prostaglandin secretion(GO:0032308) prostaglandin secretion(GO:0032310) positive regulation of fatty acid transport(GO:2000193)
0.0 0.1 GO:0045059 positive thymic T cell selection(GO:0045059)
0.0 0.0 GO:0072600 protein targeting to Golgi(GO:0000042) establishment of protein localization to Golgi(GO:0072600)
0.0 0.1 GO:0034260 negative regulation of GTPase activity(GO:0034260)
0.0 0.0 GO:0045046 protein import into peroxisome membrane(GO:0045046)
0.0 0.0 GO:0048304 positive regulation of isotype switching to IgG isotypes(GO:0048304)
0.0 0.0 GO:0032621 interleukin-18 production(GO:0032621) regulation of interleukin-18 production(GO:0032661)
0.0 0.0 GO:0061299 retina vasculature development in camera-type eye(GO:0061298) retina vasculature morphogenesis in camera-type eye(GO:0061299)
0.0 0.0 GO:0002829 negative regulation of type 2 immune response(GO:0002829)
0.0 0.3 GO:0050690 regulation of defense response to virus by virus(GO:0050690)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0001940 male pronucleus(GO:0001940)
0.0 0.1 GO:0048179 activin receptor complex(GO:0048179)
0.0 0.2 GO:0001891 phagocytic cup(GO:0001891)
0.0 0.1 GO:0032009 early phagosome(GO:0032009)
0.0 0.1 GO:0005954 calcium- and calmodulin-dependent protein kinase complex(GO:0005954)
0.0 0.1 GO:0030288 outer membrane-bounded periplasmic space(GO:0030288) periplasmic space(GO:0042597)
0.0 0.2 GO:0031672 A band(GO:0031672)
0.0 0.1 GO:0071778 obsolete WINAC complex(GO:0071778)
0.0 0.0 GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.0 0.0 GO:0044462 external encapsulating structure part(GO:0044462)
0.0 0.1 GO:0033553 rDNA heterochromatin(GO:0033553)
0.0 0.2 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.0 0.1 GO:0000791 euchromatin(GO:0000791)
0.0 0.0 GO:0032133 chromosome passenger complex(GO:0032133)
0.0 0.1 GO:0005750 mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
0.0 0.1 GO:0042101 T cell receptor complex(GO:0042101)
0.0 0.0 GO:0030312 external encapsulating structure(GO:0030312)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0045159 myosin II binding(GO:0045159)
0.0 0.1 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.0 0.1 GO:0003836 beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.0 0.3 GO:0016493 C-C chemokine receptor activity(GO:0016493)
0.0 0.1 GO:0033691 sialic acid binding(GO:0033691)
0.0 0.1 GO:0016361 activin receptor activity, type I(GO:0016361)
0.0 0.1 GO:0052813 phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) phosphatidylinositol bisphosphate kinase activity(GO:0052813)
0.0 0.1 GO:0047238 glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity(GO:0047238)
0.0 0.1 GO:0030375 thyroid hormone receptor coactivator activity(GO:0030375)
0.0 0.1 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.0 0.0 GO:0052658 inositol-1,4,5-trisphosphate 5-phosphatase activity(GO:0052658) inositol-1,3,4,5-tetrakisphosphate 5-phosphatase activity(GO:0052659)
0.0 0.1 GO:0005381 iron ion transmembrane transporter activity(GO:0005381)
0.0 0.1 GO:0003997 acyl-CoA oxidase activity(GO:0003997)
0.0 0.1 GO:0005131 growth hormone receptor binding(GO:0005131)
0.0 0.1 GO:0046923 ER retention sequence binding(GO:0046923)
0.0 0.0 GO:0004911 interleukin-2 receptor activity(GO:0004911)
0.0 0.1 GO:0016004 phospholipase activator activity(GO:0016004)
0.0 0.3 GO:0045028 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.0 0.1 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454)
0.0 0.0 GO:0030368 interleukin-17 receptor activity(GO:0030368)
0.0 0.0 GO:0016842 amidine-lyase activity(GO:0016842)
0.0 0.0 GO:0004582 dolichyl-phosphate beta-D-mannosyltransferase activity(GO:0004582)
0.0 0.0 GO:0017162 aryl hydrocarbon receptor binding(GO:0017162)
0.0 0.1 GO:0034713 type I transforming growth factor beta receptor binding(GO:0034713)
0.0 0.1 GO:0048406 nerve growth factor binding(GO:0048406)
0.0 0.2 GO:0008373 sialyltransferase activity(GO:0008373)
0.0 0.0 GO:0015204 urea transmembrane transporter activity(GO:0015204)
0.0 0.0 GO:0004449 isocitrate dehydrogenase (NAD+) activity(GO:0004449)
0.0 0.1 GO:0005095 GTPase inhibitor activity(GO:0005095)
0.0 0.1 GO:0031013 troponin I binding(GO:0031013)
0.0 0.1 GO:0005000 vasopressin receptor activity(GO:0005000)
0.0 0.0 GO:0005134 interleukin-2 receptor binding(GO:0005134)
0.0 0.1 GO:0046974 histone methyltransferase activity (H3-K9 specific)(GO:0046974)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.6 PID EPHRINB REV PATHWAY Ephrin B reverse signaling
0.0 0.2 PID TCR JNK PATHWAY JNK signaling in the CD4+ TCR pathway
0.0 0.1 ST TYPE I INTERFERON PATHWAY Type I Interferon (alpha/beta IFN) Pathway
0.0 0.1 PID TCR RAS PATHWAY Ras signaling in the CD4+ TCR pathway
0.0 0.1 SA PTEN PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.0 0.4 PID BCR 5PATHWAY BCR signaling pathway
0.0 0.1 PID ALK2 PATHWAY ALK2 signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 REACTOME BINDING AND ENTRY OF HIV VIRION Genes involved in Binding and entry of HIV virion
0.0 0.1 REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.0 0.3 REACTOME CD28 DEPENDENT VAV1 PATHWAY Genes involved in CD28 dependent Vav1 pathway
0.0 0.0 REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
0.0 0.2 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.0 0.0 REACTOME TRANSPORT OF RIBONUCLEOPROTEINS INTO THE HOST NUCLEUS Genes involved in Transport of Ribonucleoproteins into the Host Nucleus
0.0 0.1 REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX UPON TLR7 8 OR 9 STIMULATION Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
0.0 0.2 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.0 0.0 REACTOME ENDOSOMAL VACUOLAR PATHWAY Genes involved in Endosomal/Vacuolar pathway
0.0 0.0 REACTOME POST NMDA RECEPTOR ACTIVATION EVENTS Genes involved in Post NMDA receptor activation events
0.0 0.0 REACTOME SPRY REGULATION OF FGF SIGNALING Genes involved in Spry regulation of FGF signaling
0.0 0.2 REACTOME PLATELET SENSITIZATION BY LDL Genes involved in Platelet sensitization by LDL
0.0 0.3 REACTOME SEMA4D IN SEMAPHORIN SIGNALING Genes involved in Sema4D in semaphorin signaling
0.0 0.2 REACTOME NOD1 2 SIGNALING PATHWAY Genes involved in NOD1/2 Signaling Pathway
0.0 0.1 REACTOME ABORTIVE ELONGATION OF HIV1 TRANSCRIPT IN THE ABSENCE OF TAT Genes involved in Abortive elongation of HIV-1 transcript in the absence of Tat
0.0 0.2 REACTOME IL RECEPTOR SHC SIGNALING Genes involved in Interleukin receptor SHC signaling