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ENCODE: H3K4me1 ChIP-Seq of primary human cells

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CREMA is a free online tool that recognizes most important transcription factors that change the chromatin state across different samples.

Results for NR2C1

Z-value: 1.18

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Transcription factors associated with NR2C1

Gene Symbol	Gene ID	Gene Info
NR2C1 Ensembl NCBI GeneCards UniProt	ENSG00000120798.12	NR2C1

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE	Gene	Distance	Association probability	Pearson corr. coef.	P-value	Plot
NR2C1	chr12_95434630_95434781	331	0.906752	-0.70	3.7e-02	Click!
NR2C1	chr12_95465235_95465386	1483	0.446330	-0.69	3.9e-02	Click!
NR2C1	chr12_95429746_95429897	4553	0.251226	-0.50	1.7e-01	Click!
NR2C1	chr12_95462168_95462319	4550	0.245510	0.42	2.6e-01	Click!
NR2C1	chr12_95467454_95467605	50	0.979550	0.37	3.3e-01	Click!

Activity of the NR2C1 motif across conditions

Conditions sorted by the z-value of the NR2C1 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE)	Target Score	Top associated gene	Gene Info	Distance of CRE to TSS	CRE/Gene association probability
chr11_65257627_65258285	0.69	SCYL1	SCY1-like 1 (S. cerevisiae)	34592	0.08
chr9_34253979_34254272	0.52	ENSG00000222426	.	28543	0.11
chr1_94730682_94730833	0.52	ARHGAP29	Rho GTPase activating protein 29	27568	0.21
chr13_114543410_114543586	0.51	GAS6	growth arrest-specific 6	4481	0.26
chr18_56247923_56248074	0.41	ENSG00000252284	.	19865	0.14
chr15_74232933_74233272	0.40	LOXL1-AS1	LOXL1 antisense RNA 1	12513	0.14
chr20_23812897_23813048	0.39	CST2	cystatin SA	5604	0.22
chr3_14514350_14514501	0.39	SLC6A6	solute carrier family 6 (neurotransmitter transporter), member 6	675	0.76
chr1_94128945_94129096	0.38	BCAR3	breast cancer anti-estrogen resistance 3	17906	0.22
chr7_101258153_101258304	0.38	MYL10	myosin, light chain 10, regulatory	14348	0.27
chr20_48755585_48755736	0.37	TMEM189	transmembrane protein 189	7991	0.17
chr1_5998398_5998549	0.37	ENSG00000266687	.	44489	0.12
chr17_42621489_42621640	0.36	FZD2	frizzled family receptor 2	13361	0.17
chr2_37969328_37969479	0.36	CDC42EP3	CDC42 effector protein (Rho GTPase binding) 3	3792	0.35
chr18_10058872_10059075	0.35	ENSG00000263630	.	53779	0.15
chr1_115734054_115734205	0.34	RP4-663N10.1		91526	0.08
chr2_43152776_43153425	0.34	HAAO	3-hydroxyanthranilate 3,4-dioxygenase	133368	0.05
chr15_35998583_35998734	0.34	DPH6	diphthamine biosynthesis 6	160265	0.04
chr5_134581986_134582263	0.33	C5orf66	chromosome 5 open reading frame 66	91505	0.08
chr17_17642775_17643230	0.33	RAI1-AS1	RAI1 antisense RNA 1	31133	0.12
chr15_80466917_80467209	0.32	FAH	fumarylacetoacetate hydrolase (fumarylacetoacetase)	18770	0.21
chr11_113545454_113545605	0.32	TMPRSS5	transmembrane protease, serine 5	31495	0.18
chr17_18138665_18138878	0.32	LLGL1	lethal giant larvae homolog 1 (Drosophila)	9870	0.11
chr3_194930783_194931056	0.32	ENSG00000206600	.	4597	0.2
chr1_246023169_246023412	0.31	RP11-83A16.1		173563	0.03
chr11_10948038_10948189	0.31	ZBED5-AS1	ZBED5 antisense RNA 1	61305	0.11
chr12_78412506_78412657	0.31	NAV3	neuron navigator 3	52525	0.17
chr13_24001441_24001592	0.30	SACS	spastic ataxia of Charlevoix-Saguenay (sacsin)	6325	0.32
chr9_129949574_129949725	0.30	RALGPS1	Ral GEF with PH domain and SH3 binding motif 1	23375	0.16
chr8_42330645_42330848	0.30	SLC20A2	solute carrier family 20 (phosphate transporter), member 2	28015	0.16
chrX_68357230_68357381	0.30	PJA1	praja ring finger 1, E3 ubiquitin protein ligase	25232	0.27
chr5_95193163_95193314	0.29	ENSG00000250362	.	4252	0.16
chr10_69915938_69916089	0.29	ENSG00000222371	.	1823	0.38
chr17_79107219_79107370	0.29	ENSG00000221025	.	186	0.79
chr7_48134998_48135206	0.29	UPP1	uridine phosphorylase 1	6129	0.24
chr1_1476104_1476623	0.29	TMEM240	transmembrane protein 240	530	0.63
chr20_36901417_36901587	0.29	KIAA1755	KIAA1755	12328	0.16
chr20_36824784_36825086	0.29	TGM2	transglutaminase 2	29955	0.14
chr2_20383859_20384010	0.29	ENSG00000200763	.	8368	0.17
chr16_84863200_84863351	0.28	RP11-254F19.2		1406	0.4
chr1_223745292_223745443	0.28	CAPN8	calpain 8	20987	0.25
chr2_235935219_235935383	0.28	SH3BP4	SH3-domain binding protein 4	31817	0.26
chr11_35572250_35572401	0.28	PAMR1	peptidase domain containing associated with muscle regeneration 1	20477	0.22
chr14_68989421_68989674	0.27	CTD-2325P2.4		105615	0.07
chrY_18008517_18008676	0.27	ENSG00000252664	.	166050	0.04
chr5_133774585_133774736	0.27	CDKN2AIPNL	CDKN2A interacting protein N-terminal like	27071	0.14
chr1_178620335_178620486	0.27	ENSG00000266417	.	26474	0.17
chr16_85319654_85319805	0.27	ENSG00000266307	.	20202	0.23
chr21_33828676_33828827	0.27	EVA1C	eva-1 homolog C (C. elegans)	28109	0.14
chr1_183247214_183247365	0.27	NMNAT2	nicotinamide nucleotide adenylyltransferase 2	26720	0.22
chr7_25110058_25110209	0.27	CYCS	cytochrome c, somatic	54735	0.14
chr7_46525977_46526128	0.26	AC011294.3	Uncharacterized protein	210668	0.03
chr15_58836323_58836474	0.26	RP11-50C13.2		22888	0.16
chr7_130576045_130576324	0.26	ENSG00000226380	.	13886	0.26
chr15_52386582_52387272	0.26	CTD-2184D3.5		5793	0.16
chr16_66653317_66653503	0.25	CMTM3	CKLF-like MARVEL transmembrane domain containing 3	13986	0.11
chr3_142226508_142226659	0.25	RP11-383G6.3		35404	0.13
chr19_41829897_41830246	0.25	CCDC97	coiled-coil domain containing 97	4433	0.12
chr17_48287279_48287648	0.25	COL1A1	collagen, type I, alpha 1	8470	0.12
chr15_39283697_39283848	0.25	RP11-624L4.1		127142	0.06
chr1_19217476_19217627	0.25	ALDH4A1	aldehyde dehydrogenase 4 family, member A1	166	0.94
chr7_77827088_77827239	0.25	RP5-1185I7.1		207426	0.03
chr19_583116_583267	0.25	HCN2	hyperpolarization activated cyclic nucleotide-gated potassium channel 2	6702	0.09
chr19_1749097_1749397	0.25	ONECUT3	one cut homeobox 3	3125	0.18
chr22_47331632_47331783	0.25	ENSG00000221672	.	87904	0.09
chr4_6345648_6345799	0.24	PPP2R2C	protein phosphatase 2, regulatory subunit B, gamma	37874	0.18
chr22_50356250_50357150	0.24	PIM3	pim-3 oncogene	2539	0.27
chr7_105137285_105137436	0.24	PUS7	pseudouridylate synthase 7 homolog (S. cerevisiae)	11222	0.21
chr5_135389966_135390117	0.24	TGFBI	transforming growth factor, beta-induced, 68kDa	4497	0.23
chr7_69680701_69680852	0.24	AUTS2	autism susceptibility candidate 2	513349	0.0
chr3_161134127_161134278	0.24	SPTSSB	serine palmitoyltransferase, small subunit B	43534	0.19
chr16_27252390_27252716	0.24	NSMCE1	non-SMC element 1 homolog (S. cerevisiae)	8154	0.17
chr14_56954824_56954975	0.24	TMEM260	transmembrane protein 260	173	0.97
chr20_45754256_45754424	0.24	ENSG00000264901	.	41269	0.18
chr1_10958636_10958867	0.23	C1orf127	chromosome 1 open reading frame 127	49176	0.12
chr1_116610144_116610295	0.23	MAB21L3	mab-21-like 3 (C. elegans)	44157	0.15
chr2_96347293_96347444	0.23	TRIM43	tripartite motif containing 43	89602	0.08
chr3_58045428_58045645	0.23	FLNB	filamin B, beta	18520	0.24
chr3_52229790_52230208	0.23	ALAS1	aminolevulinate, delta-, synthase 1	2103	0.21
chr17_45955898_45956049	0.23	SP2	Sp2 transcription factor	17543	0.1
chr19_19746511_19746662	0.23	GMIP	GEM interacting protein	2410	0.18
chr6_82649464_82649641	0.23	ENSG00000206886	.	175811	0.03
chr1_233750521_233750914	0.23	KCNK1	potassium channel, subfamily K, member 1	967	0.63
chr8_37672483_37672634	0.23	GPR124	G protein-coupled receptor 124	17784	0.14
chr2_40661252_40661403	0.23	SLC8A1	solute carrier family 8 (sodium/calcium exchanger), member 1	3883	0.37
chr1_8087716_8087867	0.23	ERRFI1	ERBB receptor feedback inhibitor 1	1423	0.46
chr2_217555244_217555395	0.23	AC007563.5		3868	0.2
chr16_58154872_58155238	0.22	CTB-134F13.1		4266	0.14
chr6_25359520_25359732	0.22	ENSG00000207490	.	24201	0.16
chr12_106476343_106476494	0.22	NUAK1	NUAK family, SNF1-like kinase, 1	1393	0.5
chr4_10109523_10110061	0.22	ENSG00000223086	.	7716	0.16
chr6_33383896_33384047	0.22	PHF1	PHD finger protein 1	1129	0.29
chr22_37960029_37960180	0.22	CDC42EP1	CDC42 effector protein (Rho GTPase binding) 1	309	0.83
chr19_11313952_11314103	0.22	CTC-510F12.2		277	0.81
chr17_45302121_45302272	0.22	ENSG00000252088	.	4188	0.14
chr1_31381768_31382084	0.22	SDC3	syndecan 3	318	0.87
chr18_19863132_19863283	0.22	ENSG00000238907	.	22668	0.2
chr12_116820731_116820960	0.22	ENSG00000264037	.	45278	0.17
chr1_243664702_243664853	0.22	RP11-269F20.1		44057	0.19
chr19_43356078_43356229	0.22	PSG10P	pregnancy specific beta-1-glycoprotein 10, pseudogene	3618	0.2
chr19_19740386_19740663	0.22	LPAR2	lysophosphatidic acid receptor 2	785	0.49
chr18_43901802_43901953	0.22	RNF165	ring finger protein 165	4895	0.31
chr4_120655944_120656095	0.21	PDE5A	phosphodiesterase 5A, cGMP-specific	105873	0.07
chr6_109561464_109561868	0.21	ENSG00000238474	.	50895	0.12
chr19_980614_980765	0.21	WDR18	WD repeat domain 18	3642	0.1
chr5_157810587_157810765	0.21	ENSG00000222626	.	406712	0.01
chr17_42160007_42160158	0.21	G6PC3	glucose 6 phosphatase, catalytic, 3	7980	0.1
chr7_75592437_75593112	0.21	POR	P450 (cytochrome) oxidoreductase	4387	0.19
chr2_71940971_71941122	0.21	DYSF	dysferlin	247214	0.02
chr19_36822233_36822591	0.21	ENSG00000222730	.	1061	0.46
chr19_48983392_48983543	0.21	CYTH2	cytohesin 2	7858	0.1
chr20_37055054_37055242	0.21	ENSG00000225091	.	937	0.29
chr9_138944765_138944996	0.21	NACC2	NACC family member 2, BEN and BTB (POZ) domain containing	2454	0.33
chr18_68090011_68090162	0.21	ENSG00000264059	.	60627	0.13
chr13_111047343_111047494	0.20	ENSG00000238629	.	19134	0.21
chr1_53131017_53131168	0.20	FAM159A	family with sequence similarity 159, member A	32076	0.12
chr17_48424304_48424608	0.20	XYLT2	xylosyltransferase II	960	0.41
chr3_101894275_101894426	0.20	ZPLD1	zona pellucida-like domain containing 1	76262	0.12
chr17_44820432_44820772	0.20	NSF	N-ethylmaleimide-sensitive factor	16680	0.21
chr12_52661903_52662054	0.20	KRT86	keratin 86	6481	0.1
chr2_114081410_114081561	0.20	PAX8	paired box 8	44958	0.12
chr3_141163153_141163392	0.20	ZBTB38	zinc finger and BTB domain containing 38	12707	0.22
chr5_53812584_53812820	0.20	SNX18	sorting nexin 18	887	0.71
chr19_18887031_18887461	0.20	COMP	cartilage oligomeric matrix protein	14868	0.14
chr16_66957071_66957222	0.20	RRAD	Ras-related associated with diabetes	1709	0.21
chr4_152339822_152339973	0.20	FAM160A1	family with sequence similarity 160, member A1	9393	0.27
chr6_91085605_91085756	0.20	ENSG00000266760	.	63219	0.12
chr21_37583709_37583860	0.20	ENSG00000265882	.	2352	0.25
chr11_78507410_78507561	0.20	TENM4	teneurin transmembrane protein 4	8971	0.26
chr18_32958619_32958770	0.20	ZNF396	zinc finger protein 396	1393	0.48
chr16_30927719_30927870	0.19	FBXL19	F-box and leucine-rich repeat protein 19	6582	0.08
chr17_1011220_1011906	0.19	ABR	active BCR-related	777	0.69
chrX_153673360_153673855	0.19	FAM50A	family with sequence similarity 50, member A	800	0.36
chr12_115272734_115272885	0.19	ENSG00000252459	.	97300	0.08
chr6_17968817_17968981	0.19	KIF13A	kinesin family member 13A	18795	0.26
chr11_111427694_111427845	0.19	LAYN	layilin	15492	0.12
chr3_14494059_14494243	0.19	SLC6A6	solute carrier family 6 (neurotransmitter transporter), member 6	19599	0.22
chr1_109841299_109841450	0.19	MYBPHL	myosin binding protein H-like	8289	0.16
chr1_112275803_112276182	0.19	FAM212B	family with sequence similarity 212, member B	5883	0.18
chr15_75335507_75335751	0.19	PPCDC	phosphopantothenoylcysteine decarboxylase	13	0.97
chr15_37124741_37124892	0.19	ENSG00000212511	.	20025	0.26
chr11_116861004_116861155	0.19	ENSG00000264344	.	25166	0.14
chr1_23720599_23720750	0.19	TCEA3	transcription elongation factor A (SII), 3	6762	0.14
chr10_71234648_71234799	0.19	TSPAN15	tetraspanin 15	8901	0.22
chr19_13231005_13231157	0.19	NACC1	nucleus accumbens associated 1, BEN and BTB (POZ) domain containing	1930	0.18
chr7_1196429_1196848	0.18	ZFAND2A	zinc finger, AN1-type domain 2A	730	0.57
chr16_66001590_66001741	0.18	ENSG00000201999	.	334047	0.01
chr9_137118247_137118684	0.18	ENSG00000221676	.	88779	0.07
chr3_120217656_120217807	0.18	FSTL1	follistatin-like 1	47631	0.16
chr5_138350290_138350441	0.18	CTB-46B19.2		2026	0.27
chr19_1412580_1412731	0.18	CTB-25B13.13		1245	0.22
chr5_14880723_14880874	0.18	ANKH	ANKH inorganic pyrophosphate transport regulator	8911	0.23
chr2_67791651_67791912	0.18	ETAA1	Ewing tumor-associated antigen 1	167330	0.04
chr1_214666364_214666654	0.18	PTPN14	protein tyrosine phosphatase, non-receptor type 14	28363	0.24
chr3_30619633_30619797	0.18	TGFBR2	transforming growth factor, beta receptor II (70/80kDa)	28279	0.25
chr2_28914757_28915042	0.18	ENSG00000222232	.	8057	0.18
chr11_10346579_10346730	0.18	AMPD3	adenosine monophosphate deaminase 3	7436	0.17
chr19_43582973_43583124	0.18	PSG2	pregnancy specific beta-1-glycoprotein 2	3489	0.28
chr2_191587157_191587308	0.18	AC006460.2		13790	0.24
chr11_20057587_20057860	0.18	NAV2	neuron navigator 2	13087	0.19
chr19_46141846_46142168	0.18	EML2	echinoderm microtubule associated protein like 2	124	0.73
chr3_45719910_45720061	0.18	LIMD1-AS1	LIMD1 antisense RNA 1	10389	0.18
chr10_3088991_3089142	0.18	PFKP	phosphofructokinase, platelet	19459	0.26
chr1_199712128_199712279	0.18	ENSG00000263805	.	127795	0.06
chr1_16466515_16466919	0.18	RP11-276H7.2		14989	0.11
chr11_1715317_1715638	0.18	KRTAP5-6	keratin associated protein 5-6	2948	0.16
chr8_57452711_57452862	0.18	RP11-17A4.2		51129	0.16
chr19_13957292_13957443	0.18	ENSG00000207980	.	9894	0.08
chr19_18385307_18385507	0.18	KIAA1683	KIAA1683	88	0.94
chr10_21625403_21625600	0.18	ENSG00000207264	.	14611	0.25
chr18_43373207_43373358	0.18	SIGLEC15	sialic acid binding Ig-like lectin 15	32195	0.15
chr3_44866927_44867078	0.18	KIF15	kinesin family member 15	26323	0.11
chr2_20793195_20793346	0.17	HS1BP3-IT1	HS1BP3 intronic transcript 1 (non-protein coding)	962	0.61
chr15_65148885_65149111	0.17	AC069368.3	Uncharacterized protein	14851	0.13
chr1_26678105_26678256	0.17	AIM1L	absent in melanoma 1-like	2441	0.17
chr7_116963620_116964059	0.17	WNT2	wingless-type MMTV integration site family member 2	496	0.84
chr12_15789011_15789254	0.17	EPS8	epidermal growth factor receptor pathway substrate 8	26076	0.19
chr5_77189202_77189495	0.17	TBCA	tubulin folding cofactor A	24744	0.26
chr2_110459905_110460056	0.17	SOWAHC	sosondowah ankyrin repeat domain family member C	88069	0.08
chr12_1689271_1689422	0.17	WNT5B	wingless-type MMTV integration site family, member 5B	5523	0.23
chr22_38177520_38177671	0.17	ENSG00000238569	.	3938	0.13
chr6_11194834_11194985	0.17	RP3-510L9.1		21224	0.19
chr9_112832863_112833014	0.17	AKAP2	A kinase (PRKA) anchor protein 2	19539	0.26
chr3_101882560_101882711	0.17	ZPLD1	zona pellucida-like domain containing 1	64547	0.14
chr18_46351372_46351523	0.17	RP11-484L8.1		9694	0.27
chr8_102039132_102039343	0.17	ENSG00000252736	.	63966	0.1
chr7_73294883_73295034	0.17	WBSCR28	Williams-Beuren syndrome chromosome region 28	19469	0.16
chr6_3325224_3325507	0.17	RP11-506K6.4		13469	0.22
chr1_172320814_172321075	0.17	ENSG00000252354	.	3661	0.22
chr6_109792757_109793021	0.17	MICAL1	microtubule associated monooxygenase, calponin and LIM domain containing 1	5718	0.12
chr7_43912051_43912202	0.17	MRPS24	mitochondrial ribosomal protein S24	2970	0.21
chr11_126199011_126199162	0.17	RP11-712L6.5	Uncharacterized protein	24873	0.1
chr20_34055509_34055660	0.17	CEP250	centrosomal protein 250kDa	5494	0.12
chr11_131758279_131758430	0.16	AP004372.1		8648	0.25
chr8_119113494_119113873	0.16	EXT1	exostosin glycosyltransferase 1	8970	0.33
chr17_70687944_70688095	0.16	ENSG00000222545	.	22591	0.21
chr15_101611256_101611507	0.16	RP11-505E24.2		14890	0.21
chr9_137268626_137268825	0.16	ENSG00000263897	.	2532	0.35
chr19_43526713_43526864	0.16	PSG11	pregnancy specific beta-1-glycoprotein 11	3812	0.27
chr21_45230405_45230556	0.16	AP001053.11		238	0.92

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of NR2C1

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.2	GO:0006562	proline catabolic process(GO:0006562)
0.1	0.2	GO:0032509	endosome transport via multivesicular body sorting pathway(GO:0032509)
0.1	0.2	GO:0061072	iris morphogenesis(GO:0061072)
0.0	0.1	GO:0071436	sodium ion export(GO:0071436)
0.0	0.1	GO:0090084	negative regulation of inclusion body assembly(GO:0090084)
0.0	0.1	GO:0043589	skin morphogenesis(GO:0043589)
0.0	0.1	GO:0060662	tube lumen cavitation(GO:0060605) salivary gland cavitation(GO:0060662)
0.0	0.2	GO:0031274	pseudopodium assembly(GO:0031269) regulation of pseudopodium assembly(GO:0031272) positive regulation of pseudopodium assembly(GO:0031274)
0.0	0.2	GO:0015937	coenzyme A biosynthetic process(GO:0015937)
0.0	0.1	GO:0010901	regulation of very-low-density lipoprotein particle remodeling(GO:0010901)
0.0	0.0	GO:0048669	collateral sprouting in absence of injury(GO:0048669)
0.0	0.1	GO:0015014	heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.0	0.1	GO:0005997	xylulose metabolic process(GO:0005997)
0.0	0.1	GO:0035025	positive regulation of Rho protein signal transduction(GO:0035025)
0.0	0.0	GO:0009169	purine nucleoside monophosphate catabolic process(GO:0009128) ribonucleoside monophosphate catabolic process(GO:0009158) purine ribonucleoside monophosphate catabolic process(GO:0009169)
0.0	0.1	GO:0097061	dendritic spine morphogenesis(GO:0060997) regulation of dendritic spine morphogenesis(GO:0061001) dendritic spine organization(GO:0097061)
0.0	0.1	GO:0034201	response to oleic acid(GO:0034201)
0.0	0.1	GO:0048312	intracellular distribution of mitochondria(GO:0048312)
0.0	0.1	GO:0031536	positive regulation of exit from mitosis(GO:0031536)
0.0	0.1	GO:0002513	tolerance induction to self antigen(GO:0002513)
0.0	0.1	GO:0090047	obsolete positive regulation of transcription regulator activity(GO:0090047)
0.0	0.1	GO:0090073	positive regulation of protein homodimerization activity(GO:0090073)
0.0	0.1	GO:0009296	obsolete flagellum assembly(GO:0009296)
0.0	0.1	GO:0045915	positive regulation of catecholamine metabolic process(GO:0045915) positive regulation of dopamine metabolic process(GO:0045964)
0.0	0.1	GO:0070670	response to interleukin-4(GO:0070670)
0.0	0.1	GO:0002540	arachidonic acid metabolite production involved in inflammatory response(GO:0002538) leukotriene production involved in inflammatory response(GO:0002540)
0.0	0.1	GO:0015889	cobalamin transport(GO:0015889)
0.0	0.0	GO:0007221	positive regulation of transcription of Notch receptor target(GO:0007221)
0.0	0.1	GO:0005981	regulation of glycogen catabolic process(GO:0005981)
0.0	0.1	GO:0060028	convergent extension involved in axis elongation(GO:0060028)
0.0	0.1	GO:0051503	adenine nucleotide transport(GO:0051503)
0.0	0.0	GO:0071072	negative regulation of phospholipid biosynthetic process(GO:0071072)
0.0	0.1	GO:0021801	cerebral cortex radial glia guided migration(GO:0021801) telencephalon glial cell migration(GO:0022030)
0.0	0.0	GO:0044415	evasion or tolerance of host defenses by virus(GO:0019049) avoidance of host defenses(GO:0044413) evasion or tolerance of host defenses(GO:0044415) avoidance of defenses of other organism involved in symbiotic interaction(GO:0051832) evasion or tolerance of defenses of other organism involved in symbiotic interaction(GO:0051834)
0.0	0.0	GO:0006168	adenine salvage(GO:0006168) purine nucleobase salvage(GO:0043096) adenine metabolic process(GO:0046083) adenine biosynthetic process(GO:0046084)
0.0	0.2	GO:0017187	peptidyl-glutamic acid carboxylation(GO:0017187) protein carboxylation(GO:0018214)
0.0	0.1	GO:0006572	tyrosine catabolic process(GO:0006572)
0.0	0.1	GO:0032717	negative regulation of interleukin-8 production(GO:0032717)
0.0	0.0	GO:0030505	inorganic diphosphate transport(GO:0030505)
0.0	0.1	GO:0014819	regulation of skeletal muscle contraction(GO:0014819)
0.0	0.1	GO:0014012	peripheral nervous system axon regeneration(GO:0014012)
0.0	0.0	GO:0045715	negative regulation of low-density lipoprotein particle receptor biosynthetic process(GO:0045715)
0.0	0.0	GO:0060242	contact inhibition(GO:0060242)
0.0	0.0	GO:0039656	modulation by virus of host gene expression(GO:0039656)
0.0	0.1	GO:0019367	fatty acid elongation, saturated fatty acid(GO:0019367)
0.0	0.0	GO:0071830	chylomicron remnant clearance(GO:0034382) triglyceride-rich lipoprotein particle clearance(GO:0071830)
0.0	0.1	GO:0018101	protein citrullination(GO:0018101)
0.0	0.0	GO:0060831	smoothened signaling pathway involved in dorsal/ventral neural tube patterning(GO:0060831)
0.0	0.1	GO:0032469	endoplasmic reticulum calcium ion homeostasis(GO:0032469)
0.0	0.0	GO:0007132	meiotic metaphase I(GO:0007132)
0.0	0.0	GO:0030011	maintenance of cell polarity(GO:0030011)
0.0	0.0	GO:0035405	histone-threonine phosphorylation(GO:0035405)
0.0	0.1	GO:0033327	Leydig cell differentiation(GO:0033327)
0.0	0.0	GO:0000101	sulfur amino acid transport(GO:0000101) L-cystine transport(GO:0015811)
0.0	0.0	GO:0032455	nerve growth factor processing(GO:0032455)
0.0	0.1	GO:0007386	compartment pattern specification(GO:0007386)
0.0	0.0	GO:0022605	oogenesis stage(GO:0022605)
0.0	0.0	GO:0019532	oxalate transport(GO:0019532)
0.0	0.0	GO:0034145	positive regulation of toll-like receptor 4 signaling pathway(GO:0034145)
0.0	0.3	GO:0003333	amino acid transmembrane transport(GO:0003333)
0.0	0.0	GO:0072383	plus-end-directed vesicle transport along microtubule(GO:0072383) plus-end-directed organelle transport along microtubule(GO:0072386)
0.0	0.0	GO:0060539	diaphragm development(GO:0060539)
0.0	0.1	GO:0035020	regulation of Rac protein signal transduction(GO:0035020)
0.0	0.1	GO:0008655	pyrimidine-containing compound salvage(GO:0008655) pyrimidine nucleoside salvage(GO:0043097)
0.0	0.0	GO:0048149	behavioral response to ethanol(GO:0048149)
0.0	0.1	GO:0046856	phosphatidylinositol dephosphorylation(GO:0046856)
0.0	0.0	GO:0072131	kidney mesenchyme morphogenesis(GO:0072131) metanephric mesenchyme morphogenesis(GO:0072133)
0.0	0.0	GO:0006384	transcription initiation from RNA polymerase III promoter(GO:0006384)
0.0	0.1	GO:0048630	skeletal muscle tissue growth(GO:0048630)
0.0	0.0	GO:0010587	miRNA metabolic process(GO:0010586) miRNA catabolic process(GO:0010587)

Gene overrepresentation in cellular component category:

Total log-likelihood	Term	Description
0.1	GO:0070852	cell body fiber(GO:0070852)
0.1	GO:0005945	6-phosphofructokinase complex(GO:0005945)
0.1	GO:0031312	extrinsic component of organelle membrane(GO:0031312)
0.1	GO:0070022	transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.1	GO:0098651	basement membrane collagen trimer(GO:0098651)
0.0	GO:0042629	mast cell granule(GO:0042629)
0.1	GO:0005766	primary lysosome(GO:0005766) azurophil granule(GO:0042582)
0.0	GO:0031235	intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.0	GO:0030934	anchoring collagen complex(GO:0030934)
0.0	GO:0031045	dense core granule(GO:0031045)
0.1	GO:0002102	podosome(GO:0002102)
0.0	GO:0034363	intermediate-density lipoprotein particle(GO:0034363)
0.1	GO:0036454	insulin-like growth factor binding protein complex(GO:0016942) growth factor complex(GO:0036454)
0.0	GO:0008282	ATP-sensitive potassium channel complex(GO:0008282)
0.0	GO:0032449	CBM complex(GO:0032449)
0.1	GO:0005828	kinetochore microtubule(GO:0005828)
0.1	GO:0031143	pseudopodium(GO:0031143)
0.0	GO:0071062	alphav-beta3 integrin-vitronectin complex(GO:0071062)
0.0	GO:0043218	compact myelin(GO:0043218)
0.1	GO:0030315	T-tubule(GO:0030315)
0.1	GO:0001741	XY body(GO:0001741)
0.1	GO:0031232	extrinsic component of external side of plasma membrane(GO:0031232)
0.1	GO:0042627	chylomicron(GO:0042627)
0.0	GO:0031371	ubiquitin conjugating enzyme complex(GO:0031371)

Gene overrepresentation in molecular function category:

Total log-likelihood	Term	Description
0.2	GO:0048018	receptor agonist activity(GO:0048018)
0.2	GO:0005110	frizzled-2 binding(GO:0005110)
0.1	GO:0050508	glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0050508)
0.1	GO:0005432	calcium:sodium antiporter activity(GO:0005432)
0.1	GO:0033829	O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.1	GO:0001758	retinal dehydrogenase activity(GO:0001758)
0.1	GO:0060230	lipoprotein lipase activator activity(GO:0060230)
0.1	GO:0005315	inorganic phosphate transmembrane transporter activity(GO:0005315)
0.1	GO:0003872	6-phosphofructokinase activity(GO:0003872)
0.2	GO:0004029	aldehyde dehydrogenase (NAD) activity(GO:0004029)
0.1	GO:0045159	myosin II binding(GO:0045159)
0.1	GO:0030274	LIM domain binding(GO:0030274)
0.1	GO:0043184	vascular endothelial growth factor receptor 2 binding(GO:0043184)
0.1	GO:0016748	succinyltransferase activity(GO:0016748)
0.4	GO:1901682	sulfur compound transmembrane transporter activity(GO:1901682)
0.1	GO:0004515	nicotinamide-nucleotide adenylyltransferase activity(GO:0000309) nicotinate-nucleotide adenylyltransferase activity(GO:0004515)
0.1	GO:0008429	phosphatidylethanolamine binding(GO:0008429)
0.1	GO:0051636	obsolete Gram-negative bacterial cell surface binding(GO:0051636)
0.1	GO:0070576	vitamin D 24-hydroxylase activity(GO:0070576)
0.1	GO:0042285	UDP-xylosyltransferase activity(GO:0035252) xylosyltransferase activity(GO:0042285)
0.1	GO:0051371	muscle alpha-actinin binding(GO:0051371)
0.1	GO:0017166	vinculin binding(GO:0017166)
0.1	GO:0070653	high-density lipoprotein particle receptor binding(GO:0070653)
0.1	GO:0016290	palmitoyl-CoA hydrolase activity(GO:0016290)
0.1	GO:0070628	proteasome binding(GO:0070628)
0.0	GO:0019958	C-X-C chemokine binding(GO:0019958) interleukin-8 binding(GO:0019959)
0.0	GO:0004937	alpha1-adrenergic receptor activity(GO:0004937)
0.1	GO:0008379	thioredoxin peroxidase activity(GO:0008379)
0.1	GO:0003711	obsolete transcription elongation regulator activity(GO:0003711)
0.0	GO:0003953	NAD+ nucleosidase activity(GO:0003953)
0.1	GO:0004668	protein-arginine deiminase activity(GO:0004668)
0.1	GO:0042805	actinin binding(GO:0042805)
0.1	GO:0030492	hemoglobin binding(GO:0030492)
0.1	GO:0030618	transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity(GO:0030618)
0.0	GO:0043495	protein anchor(GO:0043495)
0.1	GO:0016717	oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water(GO:0016717)
0.0	GO:0035184	histone threonine kinase activity(GO:0035184)
0.1	GO:0004908	interleukin-1 receptor activity(GO:0004908)
0.0	GO:0050542	icosanoid binding(GO:0050542) fatty acid derivative binding(GO:1901567)
0.1	GO:0003810	protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.1	GO:0016641	oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor(GO:0016641)
0.2	GO:0005242	inward rectifier potassium channel activity(GO:0005242)
0.0	GO:0050265	RNA uridylyltransferase activity(GO:0050265)
0.0	GO:0005030	neurotrophin receptor activity(GO:0005030)
0.1	GO:0005007	fibroblast growth factor-activated receptor activity(GO:0005007)
0.0	GO:0047756	chondroitin 4-sulfotransferase activity(GO:0047756)
0.1	GO:0048407	platelet-derived growth factor binding(GO:0048407)
0.1	GO:0004439	phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity(GO:0004439)
0.1	GO:0032266	phosphatidylinositol-3-phosphate binding(GO:0032266)
0.1	GO:0000832	inositol hexakisphosphate kinase activity(GO:0000828) inositol hexakisphosphate 5-kinase activity(GO:0000832)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.0	0.0	PID EPHRINB REV PATHWAY	Ephrin B reverse signaling
0.0	0.0	PID MET PATHWAY	Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)
0.0	0.0	PID IL8 CXCR1 PATHWAY	IL8- and CXCR1-mediated signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Total log-likelihood	Term	Description
0.3	REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS	Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.2	REACTOME NFKB IS ACTIVATED AND SIGNALS SURVIVAL	Genes involved in NF-kB is activated and signals survival
0.3	REACTOME HS GAG DEGRADATION	Genes involved in HS-GAG degradation
0.2	REACTOME VITAMIN B5 PANTOTHENATE METABOLISM	Genes involved in Vitamin B5 (pantothenate) metabolism
0.2	REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS	Genes involved in Tandem pore domain potassium channels
0.2	REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS	Genes involved in Trafficking of GluR2-containing AMPA receptors
0.1	REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT	Genes involved in Chylomicron-mediated lipid transport