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ENCODE: H3K4me1 ChIP-Seq of primary human cells
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Results for NR2F1

Z-value: 0.80

Motif logo

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Transcription factors associated with NR2F1

Gene Symbol Gene ID Gene Info
NR2F1
ENSG00000175745.7 nuclear receptor subfamily 2 group F member 1

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE Gene Distance Association probability Pearson corr. coef. P-value Plot
chr5_92919241_92919787NR2F14710.7881390.462.1e-01Click!
chr5_92918713_92918890NR2F12420.9146730.068.7e-01Click!
chr5_92918371_92918624NR2F15460.718874-0.019.8e-01Click!

Activity of the NR2F1 motif across conditions

Conditions sorted by the z-value of the NR2F1 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE) Target Score Top associated gene Gene Info Distance of CRE to TSS CRE/Gene association probability
chr19_49099565_49099716 0.40 SPACA4
 sperm acrosome associated 4
 10360
 0.08
chr14_98635190_98635420 0.35 ENSG00000222066
 .
 162782
 0.04
chr11_3035028_3035343 0.34 CARS-AS1
 CARS antisense RNA 1
 15439
 0.11
chr6_112348251_112348537 0.26 WISP3
 WNT1 inducible signaling pathway protein 3
 26881
 0.19
chr19_39369781_39369998 0.26 RINL
 Ras and Rab interactor-like
 970
 0.3
chr1_26873022_26873700 0.22 RPS6KA1
 ribosomal protein S6 kinase, 90kDa, polypeptide 1
 1018
 0.45
chr22_42689321_42689472 0.22 TCF20
 transcription factor 20 (AR1)
 50226
 0.13
chr3_131220905_131221118 0.22 MRPL3
 mitochondrial ribosomal protein L3
 770
 0.63
chr6_137674077_137674372 0.21 IFNGR1
 interferon gamma receptor 1
 133638
 0.05
chr1_227949174_227949396 0.21 SNAP47
 synaptosomal-associated protein, 47kDa
 13521
 0.16
chr10_112123592_112123865 0.21 SMNDC1
 survival motor neuron domain containing 1
 59019
 0.12
chr19_3171495_3171646 0.21 S1PR4
 sphingosine-1-phosphate receptor 4
 7166
 0.12
chr6_154539920_154540071 0.21 IPCEF1
 interaction protein for cytohesin exchange factors 1
 27995
 0.26
chr5_74405479_74405669 0.20 GCNT4
 glucosaminyl (N-acetyl) transferase 4, core 2
 78850
 0.1
chr21_33028994_33029191 0.20 SOD1
 superoxide dismutase 1, soluble
 2843
 0.24
chr16_82686086_82686245 0.20 CDH13
 cadherin 13
 25467
 0.25
chr16_68786591_68786784 0.20 ENSG00000200558
 .
 10304
 0.16
chr3_111329937_111330088 0.19 ZBED2
 zinc finger, BED-type containing 2
 15722
 0.2
chr12_76371998_76372996 0.19 ENSG00000243420
 .
 20587
 0.2
chr14_77588217_77588634 0.18 TMEM63C
 transmembrane protein 63C
 5514
 0.16
chr15_75069001_75069262 0.18 CSK
 c-src tyrosine kinase
 5267
 0.13
chr2_131582514_131582674 0.18 AC133785.1
11973
 0.16
chr19_14141891_14142068 0.18 CTB-55O6.4
390
 0.54
chr3_132377398_132377593 0.18 UBA5
 ubiquitin-like modifier activating enzyme 5
 815
 0.49
chr13_40779977_40780128 0.18 ENSG00000207458
 .
 20912
 0.28
chr8_129406385_129406536 0.17 ENSG00000201782
 .
 173710
 0.03
chr9_79018760_79018993 0.17 RFK
 riboflavin kinase
 9455
 0.24
chr5_35902239_35902390 0.17 IL7R
 interleukin 7 receptor
 26798
 0.15
chr1_27675350_27676002 0.17 SYTL1
 synaptotagmin-like 1
 4312
 0.13
chr3_66427121_66427272 0.17 ENSG00000241587
 .
 52917
 0.15
chr3_111263954_111264147 0.17 CD96
 CD96 molecule
 3053
 0.33
chr11_65324541_65325002 0.17 LTBP3
 latent transforming growth factor beta binding protein 3
 465
 0.62
chr1_181060923_181061127 0.17 IER5
 immediate early response 5
 3387
 0.29
chr9_92445809_92446274 0.17 GADD45G
 growth arrest and DNA-damage-inducible, gamma
 226088
 0.02
chr2_85050169_85050320 0.17 TRABD2A
 TraB domain containing 2A
 57962
 0.11
chrX_48771847_48772324 0.17 PIM2
 pim-2 oncogene
 927
 0.37
chr14_99699518_99699950 0.17 AL109767.1
29551
 0.18
chr19_30328650_30328931 0.16 CCNE1
 cyclin E1
 20680
 0.25
chr5_142608359_142608828 0.16 ARHGAP26
 Rho GTPase activating protein 26
 21828
 0.23
chr11_48017026_48017177 0.16 PTPRJ
 protein tyrosine phosphatase, receptor type, J
 14822
 0.19
chr22_45065462_45065745 0.16 PRR5
 proline rich 5 (renal)
 1010
 0.59
chr15_60875764_60876131 0.16 RORA
 RAR-related orphan receptor A
 8793
 0.23
chr10_121052972_121053123 0.16 RP11-79M19.2
42647
 0.13
chr10_8445974_8446289 0.16 ENSG00000212505
 .
 252663
 0.02
chr20_57732386_57732675 0.16 ZNF831
 zinc finger protein 831
 33545
 0.19
chr11_35174879_35175121 0.16 CD44
 CD44 molecule (Indian blood group)
 14147
 0.16
chrX_128901533_128901839 0.16 SASH3
 SAM and SH3 domain containing 3
 12274
 0.19
chr2_238621913_238622064 0.16 LRRFIP1
 leucine rich repeat (in FLII) interacting protein 1
 21006
 0.21
chr18_20419374_20419602 0.16 RBBP8
 retinoblastoma binding protein 8
 41264
 0.12
chr8_131299195_131299491 0.15 ASAP1
 ArfGAP with SH3 domain, ankyrin repeat and PH domain 1
 40055
 0.21
chr1_111176210_111176587 0.15 KCNA2
 potassium voltage-gated channel, shaker-related subfamily, member 2
 2302
 0.29
chr19_9968157_9968686 0.15 OLFM2
 olfactomedin 2
 423
 0.71
chr21_43394304_43394514 0.15 C2CD2
 C2 calcium-dependent domain containing 2
 20410
 0.17
chr4_114680349_114680500 0.15 CAMK2D
 calcium/calmodulin-dependent protein kinase II delta
 1800
 0.52
chr5_75594306_75594457 0.15 RP11-466P24.6
12906
 0.28
chr10_126315256_126315705 0.15 FAM53B-AS1
 FAM53B antisense RNA 1
 76714
 0.09
chr20_31557861_31558084 0.15 EFCAB8
 EF-hand calcium binding domain 8
 10321
 0.16
chr2_112941553_112941742 0.15 FBLN7
 fibulin 7
 2187
 0.37
chr17_35081326_35081477 0.15 MRM1
 mitochondrial rRNA methyltransferase 1 homolog (S. cerevisiae)
 123010
 0.04
chr10_47644509_47644783 0.15 ANTXRLP1
 anthrax toxin receptor-like pseudogene 1
 145
 0.96
chr11_118892048_118892220 0.15 ENSG00000266398
 .
 2480
 0.09
chr22_31676559_31676796 0.15 PIK3IP1
 phosphoinositide-3-kinase interacting protein 1
 11704
 0.11
chr17_62184395_62184565 0.15 ERN1
 endoplasmic reticulum to nucleus signaling 1
 23005
 0.15
chr5_55983263_55983414 0.15 AC022431.2
 Homo sapiens uncharacterized LOC101928448 (LOC101928448), mRNA.
 81279
 0.09
chr12_67919530_67919842 0.15 DYRK2
 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 2
 122432
 0.06
chr2_235337973_235338124 0.15 ARL4C
 ADP-ribosylation factor-like 4C
 67196
 0.14
chr3_67733685_67733836 0.14 SUCLG2
 succinate-CoA ligase, GDP-forming, beta subunit
 28722
 0.26
chr9_134536993_134537144 0.14 RAPGEF1
 Rap guanine nucleotide exchange factor (GEF) 1
 35733
 0.17
chr19_9967610_9967789 0.14 OLFM2
 olfactomedin 2
 1145
 0.31
chr1_156088512_156088707 0.14 LMNA
 lamin A/C
 4096
 0.13
chr11_68108757_68109054 0.14 LRP5
 low density lipoprotein receptor-related protein 5
 28828
 0.18
chr2_69766242_69766541 0.14 ENSG00000207016
 .
 19085
 0.19
chr5_86570459_86570610 0.14 RASA1
 RAS p21 protein activator (GTPase activating protein) 1
 5773
 0.18
chr17_29797345_29797496 0.14 ENSG00000239595
 .
 4859
 0.17
chr15_39933456_39933607 0.14 FSIP1
 fibrous sheath interacting protein 1
 40404
 0.15
chr19_17111504_17111655 0.14 CTD-2528A14.1
8420
 0.14
chr8_143554044_143554195 0.14 BAI1
 brain-specific angiogenesis inhibitor 1
 8742
 0.22
chr1_206911756_206912053 0.14 ENSG00000199349
 .
 9533
 0.16
chr10_134351874_134352586 0.14 INPP5A
 inositol polyphosphate-5-phosphatase, 40kDa
 587
 0.78
chr13_80594406_80594557 0.14 SPRY2
 sprouty homolog 2 (Drosophila)
 319313
 0.01
chrX_70326040_70326438 0.14 CXorf65
 chromosome X open reading frame 65
 216
 0.87
chr6_33595892_33596043 0.14 ITPR3
 inositol 1,4,5-trisphosphate receptor, type 3
 6806
 0.15
chr3_33030408_33030590 0.14 CCR4
 chemokine (C-C motif) receptor 4
 37433
 0.17
chr5_95874776_95874927 0.14 CAST
 calpastatin
 9326
 0.22
chr20_13202929_13203194 0.14 ISM1
 isthmin 1, angiogenesis inhibitor
 643
 0.74
chr14_50411900_50412331 0.14 ENSG00000251929
 .
 43447
 0.1
chr2_219760922_219761155 0.14 WNT10A
 wingless-type MMTV integration site family, member 10A
 14155
 0.11
chr14_102297856_102298007 0.13 CTD-2017C7.1
7937
 0.16
chr11_45951042_45951193 0.13 GYLTL1B
 glycosyltransferase-like 1B
 1530
 0.28
chr2_196362777_196363039 0.13 ENSG00000202206
 .
 15852
 0.28
chr1_59278295_59278446 0.13 JUN
 jun proto-oncogene
 28585
 0.2
chr11_72493247_72493789 0.13 STARD10
 StAR-related lipid transfer (START) domain containing 10
 56
 0.94
chr10_6555656_6555821 0.13 PRKCQ
 protein kinase C, theta
 66463
 0.14
chr1_112145850_112146165 0.13 RAP1A
 RAP1A, member of RAS oncogene family
 16392
 0.16
chr14_64883279_64883430 0.13 CTD-2555O16.4
25602
 0.12
chr3_195259224_195259482 0.13 ENSG00000252620
 .
 9334
 0.16
chr20_13211744_13212262 0.13 ISM1-AS1
 ISM1 antisense RNA 1
 8318
 0.2
chr1_206976194_206976444 0.13 IL19
 interleukin 19
 4104
 0.2
chr15_42229872_42230035 0.13 CTD-2382E5.4
16338
 0.11
chr1_158899632_158899783 0.13 PYHIN1
 pyrin and HIN domain family, member 1
 879
 0.64
chr11_73686038_73686668 0.13 UCP2
 uncoupling protein 2 (mitochondrial, proton carrier)
 1698
 0.28
chr15_63898445_63898817 0.13 USP3-AS1
 USP3 antisense RNA 1
 4843
 0.21
chr2_120988966_120989173 0.13 TMEM185B
 transmembrane protein 185B
 8085
 0.17
chrX_39111302_39111453 0.13 ENSG00000207122
 .
 170839
 0.04
chr3_187883613_187883764 0.13 LPP-AS2
 LPP antisense RNA 2
 11843
 0.19
chr14_97874660_97874811 0.13 ENSG00000240730
 .
 121775
 0.07
chr11_72866229_72866512 0.13 FCHSD2
 FCH and double SH3 domains 2
 13064
 0.2
chr14_35336861_35337012 0.13 RP11-73E17.2
6613
 0.16
chr3_122292430_122292603 0.13 PARP15
 poly (ADP-ribose) polymerase family, member 15
 3933
 0.19
chr13_99188287_99188438 0.13 STK24
 serine/threonine kinase 24
 14110
 0.22
chr6_26275131_26275282 0.13 HIST1H2BI
 histone cluster 1, H2bi
 2062
 0.13
chr2_233214354_233214654 0.13 DIS3L2
 DIS3 mitotic control homolog (S. cerevisiae)-like 2
 14009
 0.14
chr7_150418122_150418385 0.13 GIMAP1
 GTPase, IMAP family member 1
 4608
 0.18
chr7_105537387_105537614 0.13 ATXN7L1
 ataxin 7-like 1
 20450
 0.25
chr1_39557935_39558086 0.13 MACF1
 microtubule-actin crosslinking factor 1
 8171
 0.18
chr21_46505200_46505358 0.13 PRED57
 HCG401283; PRED57 protein; Uncharacterized protein
 10214
 0.14
chr13_114549015_114549308 0.13 GAS6
 growth arrest-specific 6
 895
 0.65
chr1_158902586_158902737 0.13 PYHIN1
 pyrin and HIN domain family, member 1
 1303
 0.5
chr1_156697065_156697433 0.13 ISG20L2
 interferon stimulated exonuclease gene 20kDa-like 2
 978
 0.27
chr11_73079045_73079196 0.13 RELT
 RELT tumor necrosis factor receptor
 8189
 0.14
chr1_112146942_112147117 0.13 RAP1A
 RAP1A, member of RAS oncogene family
 15370
 0.17
chr3_105542619_105542770 0.13 CBLB
 Cbl proto-oncogene B, E3 ubiquitin protein ligase
 45193
 0.21
chr10_5567726_5567877 0.13 RP11-116G8.5
96
 0.8
chr15_40744962_40745272 0.13 RP11-64K12.9
1721
 0.2
chr9_140282226_140282466 0.13 ENSG00000272272
 .
 33250
 0.09
chr14_98675744_98675895 0.13 ENSG00000222066
 .
 122268
 0.06
chr4_40249519_40249765 0.13 RHOH
 ras homolog family member H
 47678
 0.14
chr1_115611623_115611842 0.13 TSPAN2
 tetraspanin 2
 20303
 0.22
chr1_112190409_112190571 0.13 ENSG00000201028
 .
 2669
 0.26
chr2_213844900_213845051 0.13 AC079610.1
41294
 0.18
chr1_203625567_203625718 0.13 ATP2B4
 ATPase, Ca++ transporting, plasma membrane 4
 26295
 0.19
chr15_70593445_70593646 0.13 ENSG00000200216
 .
 107970
 0.07
chr14_98653738_98654035 0.12 ENSG00000222066
 .
 144201
 0.05
chr9_136002577_136002769 0.12 RALGDS
 ral guanine nucleotide dissociation stimulator
 2115
 0.24
chr10_63626765_63626916 0.12 ARID5B
 AT rich interactive domain 5B (MRF1-like)
 34219
 0.2
chr22_39492254_39492443 0.12 APOBEC3H
 apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3H
 881
 0.48
chr2_231501479_231501630 0.12 ENSG00000199791
 .
 49718
 0.12
chr6_106529246_106529540 0.12 PRDM1
 PR domain containing 1, with ZNF domain
 4802
 0.27
chr15_38854255_38854406 0.12 RASGRP1
 RAS guanyl releasing protein 1 (calcium and DAG-regulated)
 1850
 0.35
chr10_82233583_82234488 0.12 TSPAN14
 tetraspanin 14
 14977
 0.2
chr5_134300560_134300711 0.12 CATSPER3
 cation channel, sperm associated 3
 2961
 0.24
chr20_37502808_37502959 0.12 ENSG00000240474
 .
 1470
 0.43
chr11_11176629_11176780 0.12 RP11-567I13.1
197269
 0.03
chr12_47615301_47615606 0.12 PCED1B
 PC-esterase domain containing 1B
 1831
 0.39
chr2_235330726_235331264 0.12 ARL4C
 ADP-ribosylation factor-like 4C
 74249
 0.13
chr8_100646172_100646444 0.12 ENSG00000243254
 .
 20002
 0.22
chr10_33401857_33402306 0.12 ENSG00000263576
 .
 14517
 0.23
chr19_18617770_18618877 0.12 ELL
 elongation factor RNA polymerase II
 14614
 0.09
chr7_112093917_112094112 0.12 IFRD1
 interferon-related developmental regulator 1
 1542
 0.44
chr20_4670873_4671024 0.12 PRNP
 prion protein
 3759
 0.26
chr7_110669949_110670394 0.12 LRRN3
 leucine rich repeat neuronal 3
 60891
 0.14
chr2_30457620_30458309 0.12 LBH
 limb bud and heart development
 2918
 0.32
chr9_77766797_77767137 0.12 ENSG00000200041
 .
 29570
 0.16
chr13_97867179_97867538 0.12 MBNL2
 muscleblind-like splicing regulator 2
 6330
 0.31
chr6_130460805_130460956 0.12 RP11-73O6.3
1539
 0.47
chr20_37433246_37433545 0.12 PPP1R16B
 protein phosphatase 1, regulatory subunit 16B
 953
 0.57
chr14_22849174_22849325 0.12 ENSG00000251002
 .
 52470
 0.09
chr19_17907446_17907815 0.12 B3GNT3
 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3
 1664
 0.26
chr12_6977477_6978263 0.12 TPI1
 triosephosphate isomerase 1
 237
 0.79
chr7_150671273_150671529 0.12 KCNH2
 potassium voltage-gated channel, subfamily H (eag-related), member 2
 3613
 0.16
chr3_59438655_59438806 0.12 C3orf67
 chromosome 3 open reading frame 67
 402920
 0.01
chr8_59170060_59170211 0.12 UBXN2B
 UBX domain protein 2B
 153688
 0.04
chr21_45341287_45341484 0.12 ENSG00000199598
 .
 1603
 0.35
chr6_16478449_16478600 0.12 ENSG00000265642
 .
 49770
 0.18
chr16_9192547_9192808 0.12 RP11-473I1.9
6028
 0.16
chr8_128222716_128223004 0.12 POU5F1B
 POU class 5 homeobox 1B
 203675
 0.03
chr2_96829307_96829548 0.12 DUSP2
 dual specificity phosphatase 2
 18248
 0.13
chr16_25124532_25124693 0.12 LCMT1
 leucine carboxyl methyltransferase 1
 1359
 0.47
chr5_133467358_133467605 0.12 TCF7
 transcription factor 7 (T-cell specific, HMG-box)
 8172
 0.21
chr18_21592600_21592808 0.12 TTC39C
 tetratricopeptide repeat domain 39C
 1680
 0.32
chr10_13149653_13149982 0.12 OPTN
 optineurin
 7592
 0.2
chr11_5839481_5839676 0.12 OR52N2
 olfactory receptor, family 52, subfamily N, member 2
 1966
 0.21
chr14_98657122_98657458 0.12 ENSG00000222066
 .
 140797
 0.05
chr2_111622829_111623021 0.12 ACOXL
 acyl-CoA oxidase-like
 60029
 0.15
chr19_18334921_18335258 0.12 PDE4C
 phosphodiesterase 4C, cAMP-specific
 214
 0.88
chr14_22749602_22749753 0.12 ENSG00000238634
 .
 138790
 0.04
chr8_41814405_41814794 0.12 KAT6A
 K(lysine) acetyltransferase 6A
 1282
 0.52
chr21_43894177_43894328 0.11 SLC37A1
 solute carrier family 37 (glucose-6-phosphate transporter), member 1
 21876
 0.11
chr4_141279191_141279342 0.11 SCOC
 short coiled-coil protein
 14511
 0.19
chr6_167534419_167534775 0.11 CCR6
 chemokine (C-C motif) receptor 6
 1660
 0.37
chr7_12770799_12771102 0.11 ENSG00000199470
 .
 30436
 0.2
chr7_2755094_2755286 0.11 AMZ1
 archaelysin family metallopeptidase 1
 27354
 0.17
chr2_240673435_240673899 0.11 AC093802.1
 Uncharacterized protein
 10887
 0.29
chr13_21402931_21403082 0.11 N6AMT2
 N-6 adenine-specific DNA methyltransferase 2 (putative)
 54918
 0.12
chr17_60548755_60548906 0.11 TLK2
 tousled-like kinase 2
 527
 0.8
chr6_16480859_16481010 0.11 ENSG00000265642
 .
 52180
 0.18
chr14_66403868_66404061 0.11 CTD-2014B16.3
 Uncharacterized protein
 67277
 0.13
chr13_52527282_52527433 0.11 ATP7B
 ATPase, Cu++ transporting, beta polypeptide
 8694
 0.22
chr20_49543758_49543983 0.11 ADNP
 activity-dependent neuroprotector homeobox
 1483
 0.3
chr19_42396817_42397275 0.11 ARHGEF1
 Rho guanine nucleotide exchange factor (GEF) 1
 1319
 0.31
chr8_97295512_97295663 0.11 PTDSS1
 phosphatidylserine synthase 1
 11833
 0.16
chr20_30973001_30973152 0.11 ASXL1
 additional sex combs like 1 (Drosophila)
 25526
 0.17
chr5_176451687_176451930 0.11 ZNF346
 zinc finger protein 346
 2072
 0.25
chr14_53620332_53620723 0.11 RP11-547D23.1
455
 0.42
chr12_107248186_107248337 0.11 RP11-144F15.1
 Uncharacterized protein
 79565
 0.08
chr15_78834636_78834986 0.11 PSMA4
 proteasome (prosome, macropain) subunit, alpha type, 4
 779
 0.51
chr13_99938059_99938240 0.11 GPR183
 G protein-coupled receptor 183
 21510
 0.17
chr9_79791700_79791851 0.11 VPS13A
 vacuolar protein sorting 13 homolog A (S. cerevisiae)
 494
 0.73
chr20_62600239_62600795 0.11 ZNF512B
 zinc finger protein 512B
 701
 0.44
chr17_45637983_45638134 0.11 ENSG00000206734
 .
 3279
 0.22

Histogram of CRE-TSS distances for CREs targeted by :

Histogram of

Rank distribution of CRE target scores:

Histogram of target CRE score.

Distribution of target CREs across different genomic regions:

Weighted Piechart of Weighted Piechart of Weighted Piechart of

Network of associatons between targets according to the STRING database.

First level regulatory network of NR2F1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0051834 evasion or tolerance of host defenses by virus(GO:0019049) avoidance of host defenses(GO:0044413) evasion or tolerance of host defenses(GO:0044415) avoidance of defenses of other organism involved in symbiotic interaction(GO:0051832) evasion or tolerance of defenses of other organism involved in symbiotic interaction(GO:0051834)
0.1 0.2 GO:0035405 histone-threonine phosphorylation(GO:0035405)
0.0 0.2 GO:0030854 positive regulation of granulocyte differentiation(GO:0030854)
0.0 0.1 GO:0031580 membrane raft polarization(GO:0001766) membrane raft distribution(GO:0031580)
0.0 0.1 GO:0010761 fibroblast migration(GO:0010761)
0.0 0.1 GO:0070266 necroptotic process(GO:0070266) programmed necrotic cell death(GO:0097300)
0.0 0.1 GO:0071569 protein ufmylation(GO:0071569)
0.0 0.1 GO:0002874 regulation of chronic inflammatory response to antigenic stimulus(GO:0002874)
0.0 0.1 GO:0061154 endothelial tube morphogenesis(GO:0061154)
0.0 0.1 GO:0040016 embryonic cleavage(GO:0040016)
0.0 0.1 GO:0033152 immunoglobulin V(D)J recombination(GO:0033152)
0.0 0.1 GO:0010459 negative regulation of heart rate(GO:0010459)
0.0 0.1 GO:0001911 negative regulation of leukocyte mediated cytotoxicity(GO:0001911)
0.0 0.1 GO:0001672 regulation of chromatin assembly or disassembly(GO:0001672)
0.0 0.1 GO:0006208 pyrimidine nucleobase catabolic process(GO:0006208) thymine catabolic process(GO:0006210) thymine metabolic process(GO:0019859)
0.0 0.1 GO:0045541 negative regulation of cholesterol biosynthetic process(GO:0045541) negative regulation of cholesterol metabolic process(GO:0090206)
0.0 0.1 GO:0034629 cellular protein complex localization(GO:0034629)
0.0 0.0 GO:0071803 regulation of podosome assembly(GO:0071801) positive regulation of podosome assembly(GO:0071803)
0.0 0.2 GO:0007172 signal complex assembly(GO:0007172)
0.0 0.2 GO:0050860 negative regulation of antigen receptor-mediated signaling pathway(GO:0050858) negative regulation of T cell receptor signaling pathway(GO:0050860)
0.0 0.1 GO:0006556 S-adenosylmethionine biosynthetic process(GO:0006556)
0.0 0.1 GO:0045722 positive regulation of gluconeogenesis(GO:0045722)
0.0 0.2 GO:0045066 regulatory T cell differentiation(GO:0045066)
0.0 0.1 GO:0052251 induction by organism of defense response of other organism involved in symbiotic interaction(GO:0052251)
0.0 0.1 GO:0097709 connective tissue replacement involved in inflammatory response wound healing(GO:0002248) connective tissue replacement(GO:0097709)
0.0 0.1 GO:0006167 AMP biosynthetic process(GO:0006167)
0.0 0.1 GO:0032621 interleukin-18 production(GO:0032621) regulation of interleukin-18 production(GO:0032661)
0.0 0.1 GO:0090286 cytoskeletal anchoring at nuclear membrane(GO:0090286)
0.0 0.1 GO:0034219 carbohydrate transmembrane transport(GO:0034219)
0.0 0.1 GO:0008295 spermidine biosynthetic process(GO:0008295)
0.0 0.0 GO:1904019 endothelial cell apoptotic process(GO:0072577) epithelial cell apoptotic process(GO:1904019) regulation of epithelial cell apoptotic process(GO:1904035) regulation of endothelial cell apoptotic process(GO:2000351)
0.0 0.1 GO:0002726 positive regulation of T cell cytokine production(GO:0002726)
0.0 0.2 GO:0048843 negative regulation of axon extension involved in axon guidance(GO:0048843)
0.0 0.1 GO:0001574 ganglioside biosynthetic process(GO:0001574)
0.0 0.1 GO:0060743 epithelial cell maturation involved in prostate gland development(GO:0060743)
0.0 0.1 GO:0048302 regulation of isotype switching to IgG isotypes(GO:0048302)
0.0 0.0 GO:0001973 adenosine receptor signaling pathway(GO:0001973) G-protein coupled purinergic receptor signaling pathway(GO:0035588)
0.0 0.0 GO:0032695 negative regulation of interleukin-12 production(GO:0032695)
0.0 0.1 GO:0002507 tolerance induction(GO:0002507)
0.0 0.1 GO:0060340 positive regulation of type I interferon-mediated signaling pathway(GO:0060340)
0.0 0.1 GO:0010957 negative regulation of calcidiol 1-monooxygenase activity(GO:0010956) negative regulation of vitamin D biosynthetic process(GO:0010957) negative regulation of vitamin metabolic process(GO:0046137)
0.0 0.1 GO:2000114 regulation of establishment of cell polarity(GO:2000114)
0.0 0.2 GO:0033631 cell-cell adhesion mediated by integrin(GO:0033631)
0.0 0.1 GO:0006198 cAMP catabolic process(GO:0006198)
0.0 0.1 GO:0045898 regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045898)
0.0 0.1 GO:0016553 base conversion or substitution editing(GO:0016553)
0.0 0.1 GO:0043518 negative regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043518) negative regulation of signal transduction by p53 class mediator(GO:1901797)
0.0 0.0 GO:0034122 negative regulation of toll-like receptor signaling pathway(GO:0034122)
0.0 0.1 GO:0090036 regulation of protein kinase C signaling(GO:0090036) positive regulation of protein kinase C signaling(GO:0090037)
0.0 0.0 GO:0051571 positive regulation of histone H3-K4 methylation(GO:0051571)
0.0 0.0 GO:0002326 B cell lineage commitment(GO:0002326)
0.0 0.1 GO:0048013 ephrin receptor signaling pathway(GO:0048013)
0.0 0.1 GO:0000729 DNA double-strand break processing(GO:0000729)
0.0 0.1 GO:0010508 positive regulation of autophagy(GO:0010508)
0.0 0.0 GO:1901419 regulation of response to alcohol(GO:1901419)
0.0 0.1 GO:0046185 aldehyde catabolic process(GO:0046185)
0.0 0.0 GO:0048537 mucosal-associated lymphoid tissue development(GO:0048537)
0.0 0.1 GO:0015014 heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.0 0.1 GO:0060836 lymphatic endothelial cell differentiation(GO:0060836)
0.0 0.1 GO:0042091 interleukin-10 biosynthetic process(GO:0042091) regulation of interleukin-10 biosynthetic process(GO:0045074)
0.0 0.1 GO:0035434 copper ion transmembrane transport(GO:0035434)
0.0 0.1 GO:0045046 protein import into peroxisome membrane(GO:0045046)
0.0 0.1 GO:0045079 negative regulation of chemokine biosynthetic process(GO:0045079)
0.0 0.1 GO:0060206 estrous cycle phase(GO:0060206)
0.0 0.1 GO:0070670 response to interleukin-4(GO:0070670)
0.0 0.1 GO:0000183 chromatin silencing at rDNA(GO:0000183)
0.0 0.2 GO:0000303 response to superoxide(GO:0000303)
0.0 0.1 GO:0031053 primary miRNA processing(GO:0031053)
0.0 0.0 GO:0002693 positive regulation of cellular extravasation(GO:0002693)
0.0 0.0 GO:0000042 protein targeting to Golgi(GO:0000042) establishment of protein localization to Golgi(GO:0072600)
0.0 0.0 GO:0070295 renal water absorption(GO:0070295)
0.0 0.1 GO:0009103 lipopolysaccharide biosynthetic process(GO:0009103)
0.0 0.0 GO:0061526 acetylcholine secretion, neurotransmission(GO:0014055) regulation of acetylcholine secretion, neurotransmission(GO:0014056) acetylcholine secretion(GO:0061526)
0.0 0.1 GO:0006346 methylation-dependent chromatin silencing(GO:0006346)
0.0 0.0 GO:0072217 negative regulation of metanephros development(GO:0072217)
0.0 0.1 GO:0045842 positive regulation of mitotic metaphase/anaphase transition(GO:0045842) positive regulation of mitotic sister chromatid separation(GO:1901970) positive regulation of metaphase/anaphase transition of cell cycle(GO:1902101)
0.0 0.1 GO:0006104 succinyl-CoA metabolic process(GO:0006104)
0.0 0.0 GO:0070602 centromeric sister chromatid cohesion(GO:0070601) regulation of centromeric sister chromatid cohesion(GO:0070602)
0.0 0.0 GO:0016242 regulation of macroautophagy(GO:0016241) negative regulation of macroautophagy(GO:0016242)
0.0 0.0 GO:0039656 modulation by virus of host gene expression(GO:0039656)
0.0 0.0 GO:0046940 nucleoside monophosphate phosphorylation(GO:0046940)
0.0 0.1 GO:0007256 activation of JNKK activity(GO:0007256)
0.0 0.1 GO:0022614 membrane to membrane docking(GO:0022614)
0.0 0.1 GO:0030206 chondroitin sulfate biosynthetic process(GO:0030206)
0.0 0.0 GO:0002823 negative regulation of adaptive immune response(GO:0002820) negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains(GO:0002823)
0.0 0.2 GO:0048024 regulation of mRNA splicing, via spliceosome(GO:0048024)
0.0 0.1 GO:0060291 long-term synaptic potentiation(GO:0060291)
0.0 0.0 GO:0048312 intracellular distribution of mitochondria(GO:0048312)
0.0 0.0 GO:0046719 intracellular transport of viral protein in host cell(GO:0019060) symbiont intracellular protein transport in host(GO:0030581) regulation by virus of viral protein levels in host cell(GO:0046719) intracellular protein transport in other organism involved in symbiotic interaction(GO:0051708)
0.0 0.1 GO:0043368 positive T cell selection(GO:0043368)
0.0 0.1 GO:0007023 post-chaperonin tubulin folding pathway(GO:0007023)
0.0 0.0 GO:0030241 skeletal muscle myosin thick filament assembly(GO:0030241) myosin filament assembly(GO:0031034) striated muscle myosin thick filament assembly(GO:0071688)
0.0 0.0 GO:0006089 lactate metabolic process(GO:0006089)
0.0 0.0 GO:0060242 contact inhibition(GO:0060242)
0.0 0.1 GO:0000768 syncytium formation by plasma membrane fusion(GO:0000768) myoblast fusion(GO:0007520)
0.0 0.0 GO:0001831 trophectodermal cellular morphogenesis(GO:0001831)
0.0 0.1 GO:0051489 regulation of filopodium assembly(GO:0051489)
0.0 0.1 GO:0042989 sequestering of actin monomers(GO:0042989)
0.0 0.0 GO:0070561 vitamin D receptor signaling pathway(GO:0070561)
0.0 0.0 GO:0035455 response to interferon-alpha(GO:0035455)
0.0 0.0 GO:0030505 inorganic diphosphate transport(GO:0030505)
0.0 0.0 GO:0033314 mitotic DNA replication checkpoint(GO:0033314)
0.0 0.1 GO:0060534 trachea cartilage development(GO:0060534)
0.0 0.0 GO:0070837 dehydroascorbic acid transport(GO:0070837)
0.0 0.1 GO:0050687 negative regulation of defense response to virus(GO:0050687)
0.0 0.1 GO:0015780 nucleotide-sugar transport(GO:0015780)
0.0 0.1 GO:0002551 mast cell chemotaxis(GO:0002551) regulation of mast cell chemotaxis(GO:0060753) positive regulation of mast cell chemotaxis(GO:0060754) mast cell migration(GO:0097531)
0.0 0.0 GO:0042118 endothelial cell activation(GO:0042118)
0.0 0.0 GO:0042816 pyridoxine metabolic process(GO:0008614) pyridoxine biosynthetic process(GO:0008615) vitamin B6 metabolic process(GO:0042816) vitamin B6 biosynthetic process(GO:0042819)
0.0 0.1 GO:0009109 coenzyme catabolic process(GO:0009109)
0.0 0.1 GO:0043267 negative regulation of potassium ion transport(GO:0043267)
0.0 0.0 GO:0015917 aminophospholipid transport(GO:0015917)
0.0 0.0 GO:0006689 ganglioside catabolic process(GO:0006689)
0.0 0.1 GO:0042023 regulation of DNA endoreduplication(GO:0032875) negative regulation of DNA endoreduplication(GO:0032876) DNA endoreduplication(GO:0042023)
0.0 0.0 GO:0032878 regulation of establishment or maintenance of cell polarity(GO:0032878)
0.0 0.0 GO:0060413 atrial septum development(GO:0003283) atrial septum morphogenesis(GO:0060413)
0.0 0.0 GO:0021780 spinal cord oligodendrocyte cell differentiation(GO:0021529) spinal cord oligodendrocyte cell fate specification(GO:0021530) oligodendrocyte cell fate specification(GO:0021778) glial cell fate specification(GO:0021780)
0.0 0.0 GO:0033033 negative regulation of myeloid cell apoptotic process(GO:0033033)
0.0 0.0 GO:2000649 regulation of sodium:proton antiporter activity(GO:0032415) regulation of sodium ion transmembrane transport(GO:1902305) regulation of sodium ion transmembrane transporter activity(GO:2000649)
0.0 0.0 GO:0031507 heterochromatin assembly(GO:0031507) heterochromatin organization(GO:0070828)
0.0 0.1 GO:0098927 early endosome to late endosome transport(GO:0045022) vesicle-mediated transport between endosomal compartments(GO:0098927)
0.0 0.2 GO:1903076 regulation of establishment of protein localization to plasma membrane(GO:0090003) regulation of protein localization to plasma membrane(GO:1903076) regulation of protein localization to cell periphery(GO:1904375)
0.0 0.1 GO:0002483 antigen processing and presentation of endogenous peptide antigen(GO:0002483) antigen processing and presentation of endogenous peptide antigen via MHC class I(GO:0019885)
0.0 0.0 GO:0018076 N-terminal peptidyl-lysine acetylation(GO:0018076)
0.0 0.0 GO:0017182 peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183)
0.0 0.0 GO:0051182 coenzyme transport(GO:0051182)
0.0 0.0 GO:0070141 response to UV-A(GO:0070141)
0.0 0.1 GO:0060896 neural plate pattern specification(GO:0060896)
0.0 0.0 GO:0015015 heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.0 0.0 GO:0046502 uroporphyrinogen III metabolic process(GO:0046502)
0.0 0.0 GO:0051451 myoblast migration(GO:0051451)
0.0 0.2 GO:0034199 activation of protein kinase A activity(GO:0034199)
0.0 0.1 GO:0032456 endocytic recycling(GO:0032456)
0.0 0.0 GO:0035268 protein mannosylation(GO:0035268) protein O-linked mannosylation(GO:0035269) mannosylation(GO:0097502)
0.0 0.0 GO:0032060 bleb assembly(GO:0032060)
0.0 0.1 GO:0006528 asparagine metabolic process(GO:0006528)
0.0 0.1 GO:0070170 regulation of tooth mineralization(GO:0070170)
0.0 0.0 GO:0014052 gamma-aminobutyric acid secretion(GO:0014051) regulation of gamma-aminobutyric acid secretion(GO:0014052)
0.0 0.0 GO:0007100 mitotic centrosome separation(GO:0007100)
0.0 0.0 GO:0050651 dermatan sulfate proteoglycan biosynthetic process(GO:0050651)
0.0 0.1 GO:0061099 negative regulation of protein tyrosine kinase activity(GO:0061099)
0.0 0.0 GO:0060972 left/right pattern formation(GO:0060972)
0.0 0.0 GO:0014721 voluntary skeletal muscle contraction(GO:0003010) twitch skeletal muscle contraction(GO:0014721)
0.0 0.0 GO:0001955 blood vessel maturation(GO:0001955)
0.0 0.1 GO:0018214 peptidyl-glutamic acid carboxylation(GO:0017187) protein carboxylation(GO:0018214)
0.0 0.0 GO:0032486 Rap protein signal transduction(GO:0032486)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0030895 apolipoprotein B mRNA editing enzyme complex(GO:0030895)
0.0 0.1 GO:0005954 calcium- and calmodulin-dependent protein kinase complex(GO:0005954)
0.0 0.1 GO:0001652 granular component(GO:0001652)
0.0 0.1 GO:0034993 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.0 0.1 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)
0.0 0.1 GO:0032449 CBM complex(GO:0032449)
0.0 0.1 GO:0031904 endosome lumen(GO:0031904)
0.0 0.1 GO:0031313 extrinsic component of vacuolar membrane(GO:0000306) extrinsic component of endosome membrane(GO:0031313)
0.0 0.1 GO:0001891 phagocytic cup(GO:0001891)
0.0 0.2 GO:0016342 catenin complex(GO:0016342)
0.0 0.1 GO:0002102 podosome(GO:0002102)
0.0 0.1 GO:0031371 ubiquitin conjugating enzyme complex(GO:0031371)
0.0 0.1 GO:0033256 I-kappaB/NF-kappaB complex(GO:0033256)
0.0 0.1 GO:0000791 euchromatin(GO:0000791)
0.0 0.1 GO:0005797 Golgi medial cisterna(GO:0005797)
0.0 0.1 GO:0005883 neurofilament(GO:0005883)
0.0 0.1 GO:0005677 chromatin silencing complex(GO:0005677)
0.0 0.1 GO:0070688 MLL5-L complex(GO:0070688)
0.0 0.0 GO:0032009 early phagosome(GO:0032009)
0.0 0.1 GO:0019907 cyclin-dependent protein kinase activating kinase holoenzyme complex(GO:0019907)
0.0 0.3 GO:0005762 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.0 0.2 GO:0035631 CD40 receptor complex(GO:0035631)
0.0 0.0 GO:0072487 MSL complex(GO:0072487)
0.0 0.0 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.0 0.1 GO:0000300 obsolete peripheral to membrane of membrane fraction(GO:0000300)
0.0 0.1 GO:0001772 immunological synapse(GO:0001772)
0.0 0.0 GO:0031312 extrinsic component of organelle membrane(GO:0031312)
0.0 0.1 GO:0016012 sarcoglycan complex(GO:0016012)
0.0 0.0 GO:0032444 activin responsive factor complex(GO:0032444)
0.0 0.0 GO:0044462 external encapsulating structure part(GO:0044462)
0.0 0.1 GO:0071564 npBAF complex(GO:0071564)
0.0 0.3 GO:0005637 nuclear inner membrane(GO:0005637)
0.0 0.1 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.0 0.2 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.0 0.0 GO:0005863 striated muscle myosin thick filament(GO:0005863)
0.0 0.1 GO:0016461 unconventional myosin complex(GO:0016461)
0.0 0.1 GO:0045261 proton-transporting ATP synthase complex, catalytic core F(1)(GO:0045261)
0.0 0.1 GO:0031305 integral component of mitochondrial inner membrane(GO:0031305)
0.0 0.0 GO:1903561 extracellular exosome(GO:0070062) extracellular vesicle(GO:1903561)
0.0 0.0 GO:0031501 mannosyltransferase complex(GO:0031501) dolichol-phosphate-mannose synthase complex(GO:0033185)
0.0 0.0 GO:0071942 XPC complex(GO:0071942)
0.0 0.0 GO:0071204 histone pre-mRNA 3'end processing complex(GO:0071204)
0.0 0.0 GO:0072357 PTW/PP1 phosphatase complex(GO:0072357)
0.0 0.0 GO:0000137 Golgi cis cisterna(GO:0000137)
0.0 0.0 GO:0000164 protein phosphatase type 1 complex(GO:0000164)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0035184 histone threonine kinase activity(GO:0035184)
0.0 0.1 GO:0003829 beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity(GO:0003829)
0.0 0.2 GO:0030618 transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity(GO:0030618)
0.0 0.0 GO:0042608 T cell receptor binding(GO:0042608)
0.0 0.1 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.0 0.1 GO:0016309 1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
0.0 0.1 GO:0008545 JUN kinase kinase activity(GO:0008545)
0.0 0.1 GO:0010340 carboxyl-O-methyltransferase activity(GO:0010340) protein carboxyl O-methyltransferase activity(GO:0051998)
0.0 0.1 GO:0052658 inositol-1,4,5-trisphosphate 5-phosphatase activity(GO:0052658) inositol-1,3,4,5-tetrakisphosphate 5-phosphatase activity(GO:0052659)
0.0 0.1 GO:0031177 phosphopantetheine binding(GO:0031177)
0.0 0.2 GO:0016493 C-C chemokine receptor activity(GO:0016493)
0.0 0.1 GO:0030375 thyroid hormone receptor coactivator activity(GO:0030375)
0.0 0.1 GO:0008321 Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.0 0.1 GO:0005006 epidermal growth factor-activated receptor activity(GO:0005006)
0.0 0.4 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.0 0.1 GO:0004774 succinate-CoA ligase activity(GO:0004774)
0.0 0.1 GO:0035197 siRNA binding(GO:0035197)
0.0 0.1 GO:0015925 galactosidase activity(GO:0015925)
0.0 0.2 GO:0004697 protein kinase C activity(GO:0004697)
0.0 0.2 GO:0070411 I-SMAD binding(GO:0070411)
0.0 0.1 GO:0048018 receptor agonist activity(GO:0048018)
0.0 0.1 GO:0070410 co-SMAD binding(GO:0070410)
0.0 0.1 GO:0046934 phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) phosphatidylinositol bisphosphate kinase activity(GO:0052813)
0.0 0.1 GO:0016842 amidine-lyase activity(GO:0016842)
0.0 0.1 GO:0015165 pyrimidine nucleotide-sugar transmembrane transporter activity(GO:0015165)
0.0 0.1 GO:0030292 protein tyrosine kinase inhibitor activity(GO:0030292)
0.0 0.3 GO:0030159 receptor signaling complex scaffold activity(GO:0030159)
0.0 0.1 GO:0016802 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.0 0.1 GO:0015271 outward rectifier potassium channel activity(GO:0015271)
0.0 0.1 GO:0016290 palmitoyl-CoA hydrolase activity(GO:0016290)
0.0 0.1 GO:0003986 acetyl-CoA hydrolase activity(GO:0003986)
0.0 0.0 GO:0050698 proteoglycan sulfotransferase activity(GO:0050698)
0.0 0.0 GO:0050897 cobalt ion binding(GO:0050897)
0.0 0.0 GO:0004911 interleukin-2 receptor activity(GO:0004911)
0.0 0.2 GO:0016861 intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861)
0.0 0.1 GO:0070097 delta-catenin binding(GO:0070097)
0.0 0.0 GO:0030368 interleukin-17 receptor activity(GO:0030368)
0.0 0.1 GO:0005315 inorganic phosphate transmembrane transporter activity(GO:0005315)
0.0 0.0 GO:0004937 alpha1-adrenergic receptor activity(GO:0004937)
0.0 0.1 GO:0070087 chromo shadow domain binding(GO:0070087)
0.0 0.0 GO:0043175 RNA polymerase core enzyme binding(GO:0043175)
0.0 0.1 GO:0004784 superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
0.0 0.2 GO:0031593 polyubiquitin binding(GO:0031593)
0.0 0.2 GO:0005095 GTPase inhibitor activity(GO:0005095)
0.0 0.1 GO:0042043 neurexin family protein binding(GO:0042043)
0.0 0.1 GO:0003945 N-acetyllactosamine synthase activity(GO:0003945)
0.0 0.1 GO:0016884 carbon-nitrogen ligase activity, with glutamine as amido-N-donor(GO:0016884)
0.0 0.1 GO:0016494 C-X-C chemokine receptor activity(GO:0016494)
0.0 0.0 GO:0005176 ErbB-2 class receptor binding(GO:0005176)
0.0 0.1 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.0 0.1 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.0 0.0 GO:0004167 dopachrome isomerase activity(GO:0004167)
0.0 0.1 GO:0008526 phosphatidylinositol transporter activity(GO:0008526)
0.0 0.1 GO:0051766 inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440) inositol trisphosphate kinase activity(GO:0051766)
0.0 0.1 GO:0008641 small protein activating enzyme activity(GO:0008641)
0.0 0.0 GO:0033300 dehydroascorbic acid transporter activity(GO:0033300)
0.0 0.1 GO:0034593 phosphatidylinositol bisphosphate phosphatase activity(GO:0034593)
0.0 0.0 GO:0005346 purine ribonucleotide transmembrane transporter activity(GO:0005346)
0.0 0.0 GO:0004517 nitric-oxide synthase activity(GO:0004517)
0.0 0.1 GO:0047238 glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity(GO:0047238)
0.0 0.0 GO:0004566 beta-glucuronidase activity(GO:0004566)
0.0 0.1 GO:0050733 RS domain binding(GO:0050733)
0.0 0.0 GO:0004308 exo-alpha-sialidase activity(GO:0004308) alpha-sialidase activity(GO:0016997)
0.0 0.0 GO:0005072 transforming growth factor beta receptor, cytoplasmic mediator activity(GO:0005072)
0.0 0.3 GO:0019843 rRNA binding(GO:0019843)
0.0 0.0 GO:0004032 alditol:NADP+ 1-oxidoreductase activity(GO:0004032)
0.0 0.0 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.0 0.0 GO:0003985 acetyl-CoA C-acetyltransferase activity(GO:0003985)
0.0 0.0 GO:0003953 NAD+ nucleosidase activity(GO:0003953)
0.0 0.0 GO:0005338 nucleotide-sugar transmembrane transporter activity(GO:0005338)
0.0 0.1 GO:0005499 vitamin D binding(GO:0005499)
0.0 0.1 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.0 0.1 GO:0051879 Hsp90 protein binding(GO:0051879)
0.0 0.1 GO:0004957 prostaglandin E receptor activity(GO:0004957)
0.0 0.0 GO:0043047 single-stranded telomeric DNA binding(GO:0043047) sequence-specific single stranded DNA binding(GO:0098847)
0.0 0.1 GO:0016833 oxo-acid-lyase activity(GO:0016833)
0.0 0.0 GO:0015254 glycerol channel activity(GO:0015254)
0.0 0.0 GO:0004582 dolichyl-phosphate beta-D-mannosyltransferase activity(GO:0004582)
0.0 0.0 GO:0003726 double-stranded RNA adenosine deaminase activity(GO:0003726)
0.0 0.0 GO:0015018 galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity(GO:0015018)
0.0 0.0 GO:0070053 thrombospondin receptor activity(GO:0070053)
0.0 0.1 GO:0051018 protein kinase A binding(GO:0051018)
0.0 0.0 GO:0003696 satellite DNA binding(GO:0003696)
0.0 0.1 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.0 PID S1P S1P2 PATHWAY S1P2 pathway
0.0 0.6 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.0 0.0 PID TCR RAS PATHWAY Ras signaling in the CD4+ TCR pathway
0.0 0.1 PID MET PATHWAY Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)
0.0 0.3 PID TCR JNK PATHWAY JNK signaling in the CD4+ TCR pathway
0.0 0.4 SA CASPASE CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.0 0.4 PID REELIN PATHWAY Reelin signaling pathway
0.0 0.6 PID CD8 TCR PATHWAY TCR signaling in naïve CD8+ T cells
0.0 0.1 PID PI3KCI PATHWAY Class I PI3K signaling events
0.0 0.1 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.0 0.1 ST TYPE I INTERFERON PATHWAY Type I Interferon (alpha/beta IFN) Pathway
0.0 0.1 SA PTEN PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.0 0.5 PID TGFBR PATHWAY TGF-beta receptor signaling
0.0 0.1 PID VEGFR1 PATHWAY VEGFR1 specific signals
0.0 0.2 PID IL2 PI3K PATHWAY IL2 signaling events mediated by PI3K
0.0 0.1 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.0 0.3 PID ECADHERIN NASCENT AJ PATHWAY E-cadherin signaling in the nascent adherens junction
0.0 0.3 SIG INSULIN RECEPTOR PATHWAY IN CARDIAC MYOCYTES Genes related to the insulin receptor pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.3 REACTOME PECAM1 INTERACTIONS Genes involved in PECAM1 interactions
0.0 0.0 REACTOME CIRCADIAN CLOCK Genes involved in Circadian Clock
0.0 0.4 REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING Genes involved in Downregulation of TGF-beta receptor signaling
0.0 0.0 REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS Genes involved in Membrane binding and targetting of GAG proteins
0.0 0.3 REACTOME NEPHRIN INTERACTIONS Genes involved in Nephrin interactions
0.0 0.0 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.0 0.1 REACTOME CD28 DEPENDENT VAV1 PATHWAY Genes involved in CD28 dependent Vav1 pathway
0.0 0.0 REACTOME CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
0.0 0.2 REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.0 0.3 REACTOME RAP1 SIGNALLING Genes involved in Rap1 signalling
0.0 0.1 REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
0.0 0.2 REACTOME GENERATION OF SECOND MESSENGER MOLECULES Genes involved in Generation of second messenger molecules
0.0 0.6 REACTOME G ALPHA Z SIGNALLING EVENTS Genes involved in G alpha (z) signalling events
0.0 0.1 REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.0 0.2 REACTOME P38MAPK EVENTS Genes involved in p38MAPK events
0.0 0.1 REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.0 0.4 REACTOME SIGNAL TRANSDUCTION BY L1 Genes involved in Signal transduction by L1
0.0 0.2 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.0 0.2 REACTOME CTLA4 INHIBITORY SIGNALING Genes involved in CTLA4 inhibitory signaling
0.0 0.6 REACTOME INTERFERON GAMMA SIGNALING Genes involved in Interferon gamma signaling
0.0 0.1 REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX UPON TLR7 8 OR 9 STIMULATION Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
0.0 0.0 REACTOME PD1 SIGNALING Genes involved in PD-1 signaling
0.0 0.0 REACTOME REGULATION OF INSULIN SECRETION BY GLUCAGON LIKE PEPTIDE1 Genes involved in Regulation of Insulin Secretion by Glucagon-like Peptide-1
0.0 0.1 REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition