Project
ENCODE: H3K4me1 ChIP-Seq of primary human cells
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CREMA is a free online tool that recognizes most important transcription factors that change the chromatin state across different samples.

Results for NR4A1

Z-value: 1.34

Motif logo

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Transcription factors associated with NR4A1

Gene Symbol Gene ID Gene Info
NR4A1
ENSG00000123358.15 NR4A1

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE Gene Distance Association probability Pearson corr. coef. P-value Plot
NR4A1chr12_52418688_5241883921470.213783-0.781.3e-02Click!
NR4A1chr12_52431172_52431676750.955545-0.732.4e-02Click!
NR4A1chr12_52435414_52435698330.961831-0.684.3e-02Click!
NR4A1chr12_52429927_524301499230.452081-0.684.3e-02Click!
NR4A1chr12_52414503_5241465420380.223270-0.665.6e-02Click!

Activity of the NR4A1 motif across conditions

Conditions sorted by the z-value of the NR4A1 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE) Target Score Top associated gene Gene Info Distance of CRE to TSS CRE/Gene association probability
chr9_16795794_16795945 0.63 BNC2
 basonuclin 2
 36417
 0.21
chr2_169371779_169371930 0.61 CERS6
 ceramide synthase 6
 59095
 0.11
chr5_139702813_139703249 0.60 PFDN1
 prefoldin subunit 1
 20325
 0.11
chr3_125322024_125322175 0.60 OSBPL11
 oxysterol binding protein-like 11
 8165
 0.22
chr14_55117533_55117800 0.58 SAMD4A
 sterile alpha motif domain containing 4A
 83029
 0.09
chr8_77806004_77806155 0.55 ENSG00000266712
 .
 73007
 0.12
chr5_9060446_9060790 0.52 ENSG00000266415
 .
 6611
 0.3
chr3_99049733_99049992 0.51 ENSG00000266030
 .
 35871
 0.23
chr13_40105934_40106139 0.50 LHFP
 lipoma HMGIC fusion partner
 71272
 0.11
chr6_150177014_150177165 0.49 RP11-350J20.12
3491
 0.15
chr19_8426697_8426848 0.49 ANGPTL4
 angiopoietin-like 4
 1401
 0.24
chr6_155521248_155521399 0.49 TIAM2
 T-cell lymphoma invasion and metastasis 2
 16448
 0.23
chr17_54218244_54218535 0.49 ANKFN1
 ankyrin-repeat and fibronectin type III domain containing 1
 12447
 0.29
chr22_37908037_37908429 0.49 CARD10
 caspase recruitment domain family, member 10
 15
 0.97
chr13_20766360_20766930 0.48 GJB2
 gap junction protein, beta 2, 26kDa
 392
 0.85
chr2_69453519_69453670 0.48 ENSG00000199460
 .
 43585
 0.14
chr6_17417778_17417929 0.48 CAP2
 CAP, adenylate cyclase-associated protein, 2 (yeast)
 23910
 0.25
chr3_124559837_124559988 0.48 ITGB5
 integrin, beta 5
 486
 0.83
chr3_71217394_71217545 0.48 FOXP1
 forkhead box P1
 30063
 0.25
chr3_159744998_159745380 0.48 LINC01100
 long intergenic non-protein coding RNA 1100
 11378
 0.19
chr5_158406881_158407032 0.47 CTD-2363C16.1
3058
 0.3
chr8_8409321_8409472 0.47 ENSG00000263616
 .
 30769
 0.21
chr9_128235565_128235716 0.47 MAPKAP1
 mitogen-activated protein kinase associated protein 1
 11140
 0.23
chr6_151134801_151134952 0.47 MTHFD1L
 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like
 51809
 0.15
chr9_16540961_16541659 0.47 RP11-183I6.2
68124
 0.12
chr22_51016890_51017529 0.47 CPT1B
 carnitine palmitoyltransferase 1B (muscle)
 113
 0.91
chr10_14027008_14027165 0.47 RP11-142M10.2
6729
 0.23
chr6_139729934_139730085 0.46 CITED2
 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2
 34252
 0.22
chr4_7136843_7136994 0.46 ENSG00000200867
 .
 22792
 0.16
chr3_197099370_197099521 0.46 ENSG00000238491
 .
 33023
 0.17
chr19_35630229_35630677 0.46 FXYD1
 FXYD domain containing ion transport regulator 1
 108
 0.92
chr5_150023934_150024085 0.46 SYNPO
 synaptopodin
 3769
 0.18
chr12_64581703_64581854 0.46 ENSG00000212298
 .
 16795
 0.15
chr7_19018368_19018519 0.45 AC004744.3
79387
 0.1
chr1_201446684_201446835 0.45 PHLDA3
 pleckstrin homology-like domain, family A, member 3
 8394
 0.16
chr20_9340813_9340964 0.45 PLCB4
 phospholipase C, beta 4
 52441
 0.17
chr7_116035147_116035298 0.45 ENSG00000252672
 .
 38046
 0.14
chr14_97041051_97041202 0.44 PAPOLA
 poly(A) polymerase alpha
 26893
 0.19
chr9_82308916_82309332 0.44 TLE4
 transducin-like enhancer of split 4 (E(sp1) homolog, Drosophila)
 10574
 0.33
chr8_141248431_141248582 0.44 TRAPPC9
 trafficking protein particle complex 9
 212523
 0.02
chr2_74810492_74810643 0.44 LOXL3
 lysyl oxidase-like 3
 27750
 0.08
chr6_33641254_33641439 0.43 SBP1
 SBP1; Uncharacterized protein
 22128
 0.12
chr6_38318537_38318688 0.43 ENSG00000238716
 .
 8393
 0.29
chr10_70815847_70816409 0.43 SRGN
 serglycin
 31746
 0.15
chr4_81157542_81157693 0.43 FGF5
 fibroblast growth factor 5
 30136
 0.17
chr8_122641106_122641257 0.42 HAS2-AS1
 HAS2 antisense RNA 1
 10352
 0.24
chr4_177707461_177707612 0.42 VEGFC
 vascular endothelial growth factor C
 6345
 0.32
chr4_7908880_7909182 0.42 AC097381.1
31697
 0.17
chr1_22188300_22188451 0.42 HSPG2
 heparan sulfate proteoglycan 2
 6486
 0.2
chr3_115525487_115525638 0.42 ENSG00000243359
 .
 31153
 0.25
chr8_48857567_48857718 0.42 PRKDC
 protein kinase, DNA-activated, catalytic polypeptide
 14227
 0.17
chr12_64491413_64491564 0.42 RP11-196H14.2
90
 0.97
chr3_97657682_97657833 0.42 CRYBG3
 beta-gamma crystallin domain containing 3
 5801
 0.23
chr6_151391460_151391611 0.42 RP1-292B18.3
14342
 0.18
chr2_238316531_238316682 0.41 COL6A3
 collagen, type VI, alpha 3
 6185
 0.22
chr1_109914631_109914782 0.41 SORT1
 sortilin 1
 21273
 0.14
chr13_102334427_102334578 0.41 ITGBL1
 integrin, beta-like 1 (with EGF-like repeat domains)
 84007
 0.1
chr1_215550097_215550248 0.41 KCTD3
 potassium channel tetramerization domain containing 3
 190563
 0.03
chr2_203012376_203012527 0.41 AC079354.3
30670
 0.12
chr8_36737433_36737584 0.40 KCNU1
 potassium channel, subfamily U, member 1
 48915
 0.19
chr7_23106099_23106250 0.40 KLHL7
 kelch-like family member 7
 39179
 0.16
chr15_63049991_63050142 0.40 TLN2
 talin 2
 723
 0.69
chr11_102042287_102042438 0.40 YAP1
 Yes-associated protein 1
 14450
 0.19
chr3_61814981_61815275 0.40 ENSG00000252420
 .
 90225
 0.1
chr4_187728365_187728516 0.40 ENSG00000252382
 .
 50170
 0.17
chr15_50123497_50124106 0.40 ATP8B4
 ATPase, class I, type 8B, member 4
 45091
 0.15
chr22_36720442_36720593 0.40 ENSG00000266345
 .
 8271
 0.19
chr3_45123520_45123671 0.40 ENSG00000252410
 .
 47515
 0.12
chr5_72760065_72760216 0.39 RP11-79P5.5
8581
 0.19
chr2_44132794_44132945 0.39 LRPPRC
 leucine-rich pentatricopeptide repeat containing
 6446
 0.21
chr5_149891888_149892039 0.39 NDST1
 N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1
 4289
 0.21
chr3_176668921_176669072 0.39 TBL1XR1-AS1
 TBL1XR1 antisense RNA 1
 93653
 0.09
chr11_8084807_8084958 0.39 RP11-236J17.5
3297
 0.19
chr8_22025544_22026075 0.39 BMP1
 bone morphogenetic protein 1
 3009
 0.15
chr6_122200022_122200173 0.39 ENSG00000222659
 .
 298430
 0.01
chr6_161650797_161650948 0.39 AGPAT4
 1-acylglycerol-3-phosphate O-acyltransferase 4
 44179
 0.21
chr12_111181471_111181864 0.39 PPP1CC
 protein phosphatase 1, catalytic subunit, gamma isozyme
 923
 0.61
chr5_82855048_82855199 0.39 VCAN-AS1
 VCAN antisense RNA 1
 3010
 0.35
chr3_123414302_123414453 0.39 MYLK
 myosin light chain kinase
 3151
 0.23
chr18_408091_408359 0.39 RP11-720L2.2
16191
 0.23
chr3_99760924_99761075 0.38 FILIP1L
 filamin A interacting protein 1-like
 72358
 0.09
chr5_97523945_97524096 0.38 ENSG00000223053
 .
 450915
 0.01
chr10_104059830_104060263 0.38 ENSG00000251989
 .
 39059
 0.11
chr20_30130007_30130314 0.38 HM13-IT1
 HM13 intronic transcript 1 (non-protein coding)
 20809
 0.11
chr12_77111390_77111541 0.38 ZDHHC17
 zinc finger, DHHC-type containing 17
 45903
 0.19
chr6_125553807_125553958 0.38 TPD52L1
 tumor protein D52-like 1
 12891
 0.27
chr11_34324437_34324812 0.38 ABTB2
 ankyrin repeat and BTB (POZ) domain containing 2
 54178
 0.15
chr15_62798764_62798915 0.37 TLN2
 talin 2
 54725
 0.15
chr8_102449532_102449683 0.37 ENSG00000239211
 .
 39446
 0.16
chr1_115843582_115843733 0.37 RP4-663N10.1
18002
 0.23
chr13_99235103_99235254 0.37 STK24-AS1
 STK24 antisense RNA 1
 5680
 0.22
chr17_38439764_38440050 0.37 CDC6
 cell division cycle 6
 3978
 0.16
chr4_26568207_26568493 0.37 TBC1D19
 TBC1 domain family, member 19
 9709
 0.25
chr2_9713569_9713720 0.37 ADAM17
 ADAM metallopeptidase domain 17
 17723
 0.16
chr11_77919440_77919591 0.37 USP35
 ubiquitin specific peptidase 35
 9499
 0.16
chr9_116928948_116929099 0.37 COL27A1
 collagen, type XXVII, alpha 1
 972
 0.61
chr14_79073045_79073196 0.37 NRXN3
 neurexin 3
 8155
 0.22
chr5_54058141_54058292 0.37 ENSG00000221073
 .
 90560
 0.09
chr18_29898352_29898503 0.37 RP11-344B2.2
31027
 0.15
chr9_128312794_128312945 0.36 RP11-12A16.3
16989
 0.22
chr1_183011913_183012064 0.36 LAMC1
 laminin, gamma 1 (formerly LAMB2)
 19393
 0.19
chr7_114569788_114570738 0.36 MDFIC
 MyoD family inhibitor domain containing
 3661
 0.38
chr3_81792742_81793030 0.36 GBE1
 glucan (1,4-alpha-), branching enzyme 1
 106
 0.98
chr2_135130048_135130199 0.36 MGAT5
 mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase
 118293
 0.06
chr16_72885085_72885236 0.36 ENSG00000251868
 .
 29269
 0.16
chr10_3766304_3766533 0.36 RP11-184A2.3
26841
 0.21
chr6_5499347_5499498 0.36 RP1-232P20.1
41114
 0.2
chr5_145356260_145356548 0.35 SH3RF2
 SH3 domain containing ring finger 2
 38964
 0.18
chr11_45880222_45880373 0.35 CRY2
 cryptochrome 2 (photolyase-like)
 11340
 0.14
chr17_12892677_12892828 0.35 RP11-597M12.1
1175
 0.44
chr8_23187305_23187456 0.35 LOXL2
 lysyl oxidase-like 2
 3628
 0.19
chr18_20290424_20290575 0.35 RP11-370A5.1
21029
 0.22
chr4_123731949_123732100 0.35 FGF2
 fibroblast growth factor 2 (basic)
 15839
 0.18
chr3_189777180_189777331 0.35 ENSG00000265045
 .
 54468
 0.12
chr22_38850403_38851076 0.35 KCNJ4
 potassium inwardly-rectifying channel, subfamily J, member 4
 466
 0.74
chr5_145282601_145282752 0.35 GRXCR2
 glutaredoxin, cysteine rich 2
 30145
 0.18
chr12_27735859_27736010 0.34 PPFIBP1
 PTPRF interacting protein, binding protein 1 (liprin beta 1)
 16347
 0.22
chr12_27776651_27776802 0.34 PPFIBP1
 PTPRF interacting protein, binding protein 1 (liprin beta 1)
 24445
 0.18
chr13_102050888_102051039 0.34 NALCN
 sodium leak channel, non-selective
 542
 0.86
chr17_45681221_45681372 0.34 NPEPPS
 aminopeptidase puromycin sensitive
 14420
 0.15
chr10_105409169_105409599 0.34 SH3PXD2A
 SH3 and PX domains 2A
 12078
 0.17
chr15_58732495_58732646 0.34 LIPC
 lipase, hepatic
 8380
 0.21
chr15_79133522_79133673 0.34 ADAMTS7
 ADAM metallopeptidase with thrombospondin type 1 motif, 7
 29824
 0.14
chr2_151060861_151061012 0.34 RND3
 Rho family GTPase 3
 280960
 0.01
chr5_111304224_111304663 0.34 NREP-AS1
 NREP antisense RNA 1
 706
 0.74
chr15_90577870_90579058 0.34 ENSG00000265871
 .
 28477
 0.12
chr10_123513005_123513156 0.34 RP11-78A18.2
17262
 0.26
chr17_39677520_39677671 0.34 KRT15
 keratin 15
 324
 0.76
chr11_33713061_33713264 0.34 RP4-541C22.5
5085
 0.19
chr2_48776419_48776570 0.33 STON1
 stonin 1
 19169
 0.18
chr3_159322379_159322530 0.33 IQCJ-SCHIP1
 IQCJ-SCHIP1 readthrough
 159048
 0.04
chr11_65185776_65186435 0.33 ENSG00000245532
 .
 25824
 0.09
chr5_37724043_37724194 0.33 ENSG00000206743
 .
 23579
 0.23
chr18_46133340_46133491 0.33 ENSG00000266276
 .
 63556
 0.11
chr1_44153927_44154092 0.33 KDM4A-AS1
 KDM4A antisense RNA 1
 16131
 0.13
chr1_56333446_56333597 0.33 PIGQP1
 phosphatidylinositol glycan anchor biosynthesis, class Q pseudogene 1
 71432
 0.14
chr2_227373807_227373958 0.33 ENSG00000263363
 .
 149627
 0.05
chr1_24372561_24372810 0.33 RP11-293P20.2
5360
 0.16
chr3_150042680_150042831 0.33 TSC22D2
 TSC22 domain family, member 2
 83367
 0.1
chr12_58951335_58951486 0.33 RP11-362K2.2
 Protein LOC100506869
 13503
 0.31
chr6_132511422_132511573 0.33 ENSG00000265669
 .
 75094
 0.11
chr3_17225666_17225817 0.33 ENSG00000252976
 .
 48527
 0.18
chr1_218613189_218613340 0.32 C1orf143
 chromosome 1 open reading frame 143
 70174
 0.11
chr14_93707328_93707479 0.32 UBR7
 ubiquitin protein ligase E3 component n-recognin 7 (putative)
 22376
 0.14
chr22_32287620_32287871 0.32 DEPDC5
 DEP domain containing 5
 38843
 0.11
chr22_35614709_35614860 0.32 ENSG00000238584
 .
 30981
 0.16
chr11_14279964_14280119 0.32 RP11-21L19.1
15196
 0.24
chr17_79994361_79995124 0.32 DCXR
 dicarbonyl/L-xylulose reductase
 129
 0.86
chr8_97962343_97962494 0.32 CPQ
 carboxypeptidase Q
 79279
 0.11
chr20_49015663_49015814 0.32 ENSG00000244376
 .
 30282
 0.2
chr17_19806867_19807136 0.32 RP11-209D14.4
26049
 0.15
chr3_53755380_53755531 0.32 CACNA1D
 calcium channel, voltage-dependent, L type, alpha 1D subunit
 27652
 0.19
chr2_101349772_101349923 0.32 NPAS2
 neuronal PAS domain protein 2
 86767
 0.08
chr6_56659004_56659155 0.32 DST
 dystonin
 8402
 0.27
chr12_95477782_95477933 0.32 FGD6
 FYVE, RhoGEF and PH domain containing 6
 7706
 0.22
chr15_68881461_68881612 0.32 CORO2B
 coronin, actin binding protein, 2B
 9963
 0.29
chr2_100427591_100427742 0.32 AFF3
 AF4/FMR2 family, member 3
 232834
 0.02
chr11_31426039_31426190 0.32 ENSG00000221338
 .
 30996
 0.15
chr5_5019028_5019179 0.31 ENSG00000223007
 .
 107056
 0.07
chr18_8794984_8795135 0.31 SOGA2
 SOGA family member 2
 5387
 0.22
chr1_183256424_183256575 0.31 NMNAT2
 nicotinamide nucleotide adenylyltransferase 2
 17510
 0.25
chr11_130766878_130767075 0.31 SNX19
 sorting nexin 19
 3207
 0.38
chr15_39578580_39578731 0.31 RP11-624L4.1
12571
 0.25
chr9_72771410_72771561 0.31 MAMDC2-AS1
 MAMDC2 antisense RNA 1
 971
 0.62
chr5_57134689_57134840 0.31 ENSG00000266864
 .
 34109
 0.24
chr12_66334915_66335185 0.31 RP11-366L20.3
7209
 0.2
chr7_25469583_25469734 0.31 ENSG00000222101
 .
 140630
 0.05
chr3_149120364_149120515 0.31 TM4SF1-AS1
 TM4SF1 antisense RNA 1
 24433
 0.16
chr11_10346579_10346730 0.31 AMPD3
 adenosine monophosphate deaminase 3
 7436
 0.17
chr16_82867745_82867896 0.31 ENSG00000221395
 .
 7871
 0.22
chr7_107590153_107590304 0.31 CTB-13F3.1
7667
 0.2
chr1_235752042_235752193 0.31 GNG4
 guanine nucleotide binding protein (G protein), gamma 4
 6662
 0.28
chr19_17664061_17664672 0.31 COLGALT1
 collagen beta(1-O)galactosyltransferase 1
 2037
 0.21
chr14_23315488_23315639 0.31 ENSG00000212335
 .
 6374
 0.08
chr3_51655320_51655571 0.31 RAD54L2
 RAD54-like 2 (S. cerevisiae)
 7962
 0.17
chr4_57928513_57928664 0.31 ENSG00000238541
 .
 43923
 0.11
chr14_62086933_62087144 0.31 RP11-47I22.3
 Uncharacterized protein
 27100
 0.2
chr16_64787221_64787372 0.31 CDH11
 cadherin 11, type 2, OB-cadherin (osteoblast)
 306285
 0.01
chr3_168954605_168954756 0.30 MECOM
 MDS1 and EVI1 complex locus
 32346
 0.24
chr2_228683614_228683765 0.30 CCL20
 chemokine (C-C motif) ligand 20
 5119
 0.24
chr6_121828413_121828642 0.30 ENSG00000201379
 .
 35245
 0.16
chr12_54417117_54417268 0.30 HOXC6
 homeobox C6
 4950
 0.07
chr10_93373920_93374071 0.30 PPP1R3C
 protein phosphatase 1, regulatory subunit 3C
 18816
 0.27
chr4_101219772_101219923 0.30 DDIT4L
 DNA-damage-inducible transcript 4-like
 107908
 0.07
chr11_12724962_12725113 0.30 TEAD1
 TEA domain family member 1 (SV40 transcriptional enhancer factor)
 27987
 0.23
chr4_24280233_24280384 0.30 ENSG00000222262
 .
 142616
 0.05
chr10_24724571_24724722 0.30 KIAA1217
 KIAA1217
 13716
 0.25
chr4_26034936_26035087 0.30 SMIM20
 small integral membrane protein 20
 119080
 0.06
chr7_38039496_38039647 0.30 SFRP4
 secreted frizzled-related protein 4
 25726
 0.24
chr22_31479008_31479415 0.30 RP3-412A9.16
340
 0.68
chr7_48221146_48221297 0.30 ABCA13
 ATP-binding cassette, sub-family A (ABC1), member 13
 10164
 0.28
chr6_110282853_110283270 0.30 GPR6
 G protein-coupled receptor 6
 16453
 0.28
chr4_157695429_157695580 0.30 RP11-154F14.2
67007
 0.12
chr3_11681753_11682311 0.29 VGLL4
 vestigial like 4 (Drosophila)
 3366
 0.28
chr14_71586472_71586623 0.29 PCNX
 pecanex homolog (Drosophila)
 10810
 0.29
chr12_69893020_69893171 0.29 FRS2
 fibroblast growth factor receptor substrate 2
 28881
 0.18
chr3_170716362_170716513 0.29 ENSG00000199488
 .
 3615
 0.27
chr9_133670542_133670756 0.29 ABL1
 c-abl oncogene 1, non-receptor tyrosine kinase
 39804
 0.16
chr20_43971586_43971737 0.29 SDC4
 syndecan 4
 5403
 0.13
chr11_112126727_112126878 0.29 AP002884.2
 LOC100132686 protein; Uncharacterized protein
 4186
 0.14

Histogram of CRE-TSS distances for CREs targeted by :

Histogram of

Rank distribution of CRE target scores:

Histogram of target CRE score.

Distribution of target CREs across different genomic regions:

Weighted Piechart of Weighted Piechart of Weighted Piechart of

Network of associatons between targets according to the STRING database.

StringDB image

First level regulatory network of NR4A1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0005997 xylulose metabolic process(GO:0005997)
0.1 0.4 GO:0051005 negative regulation of lipoprotein lipase activity(GO:0051005)
0.1 0.5 GO:0016264 gap junction assembly(GO:0016264)
0.1 0.3 GO:0033152 immunoglobulin V(D)J recombination(GO:0033152)
0.1 0.2 GO:0060753 mast cell chemotaxis(GO:0002551) regulation of mast cell chemotaxis(GO:0060753) positive regulation of mast cell chemotaxis(GO:0060754) mast cell migration(GO:0097531)
0.1 0.5 GO:0006853 carnitine shuttle(GO:0006853) carnitine transmembrane transport(GO:1902603)
0.1 0.2 GO:0007221 positive regulation of transcription of Notch receptor target(GO:0007221)
0.1 0.2 GO:0001778 plasma membrane repair(GO:0001778)
0.0 0.1 GO:0010966 regulation of phosphate transport(GO:0010966)
0.0 0.1 GO:0019322 pentose biosynthetic process(GO:0019322)
0.0 0.1 GO:0071436 sodium ion export(GO:0071436)
0.0 0.0 GO:0070873 regulation of polysaccharide metabolic process(GO:0032881) regulation of glycogen metabolic process(GO:0070873) positive regulation of glycogen metabolic process(GO:0070875)
0.0 0.2 GO:0010901 regulation of very-low-density lipoprotein particle remodeling(GO:0010901)
0.0 0.3 GO:0007185 transmembrane receptor protein tyrosine phosphatase signaling pathway(GO:0007185)
0.0 0.1 GO:0010831 positive regulation of myotube differentiation(GO:0010831)
0.0 0.1 GO:0060129 thyroid-stimulating hormone-secreting cell differentiation(GO:0060129)
0.0 0.0 GO:0048669 collateral sprouting in absence of injury(GO:0048669)
0.0 0.1 GO:0010193 response to ozone(GO:0010193)
0.0 0.1 GO:0007132 meiotic metaphase I(GO:0007132)
0.0 0.1 GO:0048149 behavioral response to ethanol(GO:0048149)
0.0 0.1 GO:0006701 progesterone biosynthetic process(GO:0006701)
0.0 0.4 GO:1901222 activation of NF-kappaB-inducing kinase activity(GO:0007250) NIK/NF-kappaB signaling(GO:0038061) regulation of NIK/NF-kappaB signaling(GO:1901222) positive regulation of NIK/NF-kappaB signaling(GO:1901224)
0.0 0.2 GO:0007171 activation of transmembrane receptor protein tyrosine kinase activity(GO:0007171)
0.0 0.1 GO:0043589 skin morphogenesis(GO:0043589)
0.0 0.1 GO:0009169 purine nucleoside monophosphate catabolic process(GO:0009128) ribonucleoside monophosphate catabolic process(GO:0009158) purine ribonucleoside monophosphate catabolic process(GO:0009169)
0.0 0.2 GO:0097061 dendritic spine morphogenesis(GO:0060997) regulation of dendritic spine morphogenesis(GO:0061001) dendritic spine organization(GO:0097061)
0.0 0.3 GO:0007016 cytoskeletal anchoring at plasma membrane(GO:0007016)
0.0 0.1 GO:0032226 positive regulation of synaptic transmission, dopaminergic(GO:0032226)
0.0 0.1 GO:0015889 cobalamin transport(GO:0015889)
0.0 0.1 GO:0060831 smoothened signaling pathway involved in dorsal/ventral neural tube patterning(GO:0060831)
0.0 0.1 GO:0045988 negative regulation of striated muscle contraction(GO:0045988)
0.0 0.1 GO:0071731 response to nitric oxide(GO:0071731)
0.0 0.2 GO:0048208 vesicle targeting, rough ER to cis-Golgi(GO:0048207) COPII vesicle coating(GO:0048208) COPII-coated vesicle budding(GO:0090114)
0.0 0.4 GO:0035329 hippo signaling(GO:0035329)
0.0 0.1 GO:0034638 phosphatidylcholine catabolic process(GO:0034638)
0.0 0.1 GO:0009414 response to water deprivation(GO:0009414) response to water(GO:0009415)
0.0 0.1 GO:0048702 embryonic neurocranium morphogenesis(GO:0048702)
0.0 0.1 GO:0007028 cytoplasm organization(GO:0007028)
0.0 0.1 GO:0007352 zygotic specification of dorsal/ventral axis(GO:0007352)
0.0 0.2 GO:0015937 coenzyme A biosynthetic process(GO:0015937)
0.0 0.1 GO:0060743 epithelial cell maturation involved in prostate gland development(GO:0060743)
0.0 0.1 GO:0051549 regulation of keratinocyte migration(GO:0051547) positive regulation of keratinocyte migration(GO:0051549)
0.0 0.1 GO:0045162 clustering of voltage-gated sodium channels(GO:0045162)
0.0 0.0 GO:0010002 cardioblast differentiation(GO:0010002)
0.0 0.1 GO:0090073 positive regulation of protein homodimerization activity(GO:0090073)
0.0 0.1 GO:0072216 positive regulation of metanephros development(GO:0072216)
0.0 0.1 GO:0051088 PMA-inducible membrane protein ectodomain proteolysis(GO:0051088)
0.0 0.1 GO:0043501 skeletal muscle adaptation(GO:0043501)
0.0 0.1 GO:0061042 vascular wound healing(GO:0061042) regulation of vascular wound healing(GO:0061043)
0.0 0.2 GO:0002347 response to tumor cell(GO:0002347)
0.0 0.1 GO:0046501 protoporphyrinogen IX metabolic process(GO:0046501)
0.0 0.0 GO:0010566 regulation of ketone biosynthetic process(GO:0010566) regulation of aldosterone metabolic process(GO:0032344) regulation of aldosterone biosynthetic process(GO:0032347)
0.0 0.1 GO:0060340 positive regulation of type I interferon-mediated signaling pathway(GO:0060340)
0.0 0.1 GO:0090273 regulation of somatostatin secretion(GO:0090273)
0.0 0.1 GO:0032413 negative regulation of ion transmembrane transporter activity(GO:0032413)
0.0 0.1 GO:0032467 positive regulation of cytokinesis(GO:0032467)
0.0 0.1 GO:0031641 regulation of myelination(GO:0031641)
0.0 0.0 GO:0015868 purine ribonucleotide transport(GO:0015868)
0.0 0.1 GO:0006927 obsolete transformed cell apoptotic process(GO:0006927)
0.0 0.3 GO:0010171 body morphogenesis(GO:0010171)
0.0 0.1 GO:0090047 obsolete positive regulation of transcription regulator activity(GO:0090047)
0.0 0.2 GO:0034446 substrate adhesion-dependent cell spreading(GO:0034446)
0.0 0.1 GO:0046902 regulation of mitochondrial membrane permeability(GO:0046902) regulation of membrane permeability(GO:0090559)
0.0 0.1 GO:0031340 positive regulation of vesicle fusion(GO:0031340)
0.0 0.1 GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.0 0.5 GO:0010811 positive regulation of cell-substrate adhesion(GO:0010811)
0.0 0.1 GO:0072268 pattern specification involved in metanephros development(GO:0072268)
0.0 0.0 GO:0033603 positive regulation of dopamine secretion(GO:0033603)
0.0 0.1 GO:0045077 negative regulation of interferon-gamma biosynthetic process(GO:0045077)
0.0 0.1 GO:0090136 epithelial cell-cell adhesion(GO:0090136)
0.0 0.1 GO:0032927 positive regulation of activin receptor signaling pathway(GO:0032927)
0.0 0.1 GO:0060363 cranial suture morphogenesis(GO:0060363) craniofacial suture morphogenesis(GO:0097094)
0.0 0.0 GO:0032261 purine nucleotide salvage(GO:0032261)
0.0 0.2 GO:0031116 positive regulation of microtubule polymerization(GO:0031116)
0.0 0.0 GO:0048319 axial mesoderm morphogenesis(GO:0048319)
0.0 0.0 GO:0035511 oxidative DNA demethylation(GO:0035511)
0.0 0.1 GO:0019673 GDP-mannose metabolic process(GO:0019673)
0.0 0.1 GO:1901889 negative regulation of focal adhesion assembly(GO:0051895) negative regulation of cell junction assembly(GO:1901889) negative regulation of adherens junction organization(GO:1903392)
0.0 0.1 GO:0048745 smooth muscle tissue development(GO:0048745)
0.0 0.0 GO:0045002 DNA double-strand break processing involved in repair via single-strand annealing(GO:0010792) double-strand break repair via single-strand annealing(GO:0045002)
0.0 0.0 GO:0009191 nucleoside diphosphate catabolic process(GO:0009134) ribonucleoside diphosphate catabolic process(GO:0009191)
0.0 0.0 GO:0070296 sarcoplasmic reticulum calcium ion transport(GO:0070296)
0.0 0.0 GO:0060457 negative regulation of digestive system process(GO:0060457)
0.0 0.0 GO:0032509 endosome transport via multivesicular body sorting pathway(GO:0032509)
0.0 0.0 GO:0032455 nerve growth factor processing(GO:0032455)
0.0 0.0 GO:0046599 regulation of centriole replication(GO:0046599)
0.0 0.0 GO:0030538 embryonic genitalia morphogenesis(GO:0030538)
0.0 0.0 GO:0033314 mitotic DNA replication checkpoint(GO:0033314)
0.0 0.1 GO:0045071 negative regulation of viral genome replication(GO:0045071)
0.0 0.0 GO:0003032 detection of oxygen(GO:0003032)
0.0 0.1 GO:0090162 establishment of epithelial cell polarity(GO:0090162)
0.0 0.1 GO:0006572 tyrosine catabolic process(GO:0006572)
0.0 0.0 GO:0048840 otolith development(GO:0048840)
0.0 0.1 GO:0009396 folic acid-containing compound biosynthetic process(GO:0009396)
0.0 0.0 GO:0071694 sequestering of extracellular ligand from receptor(GO:0035581) sequestering of TGFbeta in extracellular matrix(GO:0035583) protein localization to extracellular region(GO:0071692) maintenance of protein location in extracellular region(GO:0071694) extracellular regulation of signal transduction(GO:1900115) extracellular negative regulation of signal transduction(GO:1900116)
0.0 0.0 GO:0009756 carbohydrate mediated signaling(GO:0009756)
0.0 0.0 GO:0001757 somite specification(GO:0001757)
0.0 0.1 GO:0045197 establishment or maintenance of epithelial cell apical/basal polarity(GO:0045197)
0.0 0.1 GO:0008218 bioluminescence(GO:0008218)
0.0 0.0 GO:0006435 threonyl-tRNA aminoacylation(GO:0006435)
0.0 0.1 GO:0072383 plus-end-directed vesicle transport along microtubule(GO:0072383) plus-end-directed organelle transport along microtubule(GO:0072386)
0.0 0.1 GO:0040037 negative regulation of fibroblast growth factor receptor signaling pathway(GO:0040037)
0.0 0.2 GO:0098743 cartilage condensation(GO:0001502) cell aggregation(GO:0098743)
0.0 0.1 GO:0009744 response to sucrose(GO:0009744) response to disaccharide(GO:0034285)
0.0 0.1 GO:0051593 response to folic acid(GO:0051593)
0.0 0.0 GO:0050774 negative regulation of dendrite morphogenesis(GO:0050774)
0.0 0.2 GO:0019433 triglyceride catabolic process(GO:0019433) neutral lipid catabolic process(GO:0046461) acylglycerol catabolic process(GO:0046464)
0.0 0.0 GO:0061047 foregut regionalization(GO:0060423) lung field specification(GO:0060424) lung induction(GO:0060492) regulation of branching involved in lung morphogenesis(GO:0061046) positive regulation of branching involved in lung morphogenesis(GO:0061047)
0.0 0.2 GO:0030511 positive regulation of transforming growth factor beta receptor signaling pathway(GO:0030511) positive regulation of cellular response to transforming growth factor beta stimulus(GO:1903846)
0.0 0.0 GO:0032410 negative regulation of transporter activity(GO:0032410)
0.0 0.0 GO:0006667 sphinganine metabolic process(GO:0006667)
0.0 0.1 GO:0043968 histone H2A acetylation(GO:0043968)
0.0 0.1 GO:0042487 regulation of odontogenesis of dentin-containing tooth(GO:0042487)
0.0 0.0 GO:0015919 peroxisomal membrane transport(GO:0015919)
0.0 0.0 GO:0051451 myoblast migration(GO:0051451)
0.0 0.0 GO:0046113 nucleobase catabolic process(GO:0046113)
0.0 0.0 GO:0048625 myoblast fate commitment(GO:0048625)
0.0 0.0 GO:0045715 negative regulation of low-density lipoprotein particle receptor biosynthetic process(GO:0045715)
0.0 0.0 GO:0070050 neuron cellular homeostasis(GO:0070050)
0.0 0.0 GO:0010459 negative regulation of heart rate(GO:0010459)
0.0 0.3 GO:0005978 glycogen biosynthetic process(GO:0005978) glucan biosynthetic process(GO:0009250)
0.0 0.0 GO:0021869 forebrain ventricular zone progenitor cell division(GO:0021869)
0.0 0.0 GO:0019049 evasion or tolerance of host defenses by virus(GO:0019049) avoidance of host defenses(GO:0044413) evasion or tolerance of host defenses(GO:0044415) avoidance of defenses of other organism involved in symbiotic interaction(GO:0051832) evasion or tolerance of defenses of other organism involved in symbiotic interaction(GO:0051834)
0.0 0.0 GO:0051590 positive regulation of neurotransmitter transport(GO:0051590)
0.0 0.0 GO:0031953 negative regulation of protein autophosphorylation(GO:0031953)
0.0 0.0 GO:0035520 monoubiquitinated protein deubiquitination(GO:0035520)
0.0 0.0 GO:0060648 mammary gland bud morphogenesis(GO:0060648)
0.0 0.0 GO:0070849 response to epidermal growth factor(GO:0070849) cellular response to epidermal growth factor stimulus(GO:0071364)
0.0 0.0 GO:0032525 somite rostral/caudal axis specification(GO:0032525)
0.0 0.0 GO:0006654 phosphatidic acid biosynthetic process(GO:0006654)
0.0 0.0 GO:0048807 female genitalia morphogenesis(GO:0048807)
0.0 0.0 GO:0007440 foregut morphogenesis(GO:0007440) embryonic foregut morphogenesis(GO:0048617)
0.0 0.0 GO:0060174 limb bud formation(GO:0060174)
0.0 0.1 GO:0007029 endoplasmic reticulum organization(GO:0007029)
0.0 0.1 GO:0006448 regulation of translational elongation(GO:0006448)
0.0 0.1 GO:0045749 obsolete negative regulation of S phase of mitotic cell cycle(GO:0045749)
0.0 0.0 GO:0046874 quinolinate metabolic process(GO:0046874)
0.0 0.0 GO:0071379 cellular response to prostaglandin stimulus(GO:0071379)
0.0 0.0 GO:0060666 dichotomous subdivision of terminal units involved in salivary gland branching(GO:0060666)
0.0 0.1 GO:0002566 somatic diversification of immune receptors via somatic mutation(GO:0002566) somatic hypermutation of immunoglobulin genes(GO:0016446)
0.0 0.1 GO:0030502 negative regulation of bone mineralization(GO:0030502)
0.0 0.0 GO:0060083 smooth muscle contraction involved in micturition(GO:0060083)
0.0 0.0 GO:0009051 pentose-phosphate shunt, oxidative branch(GO:0009051)
0.0 0.0 GO:0003323 type B pancreatic cell development(GO:0003323)
0.0 0.0 GO:0033089 positive regulation of T cell differentiation in thymus(GO:0033089) positive regulation of thymocyte aggregation(GO:2000400)
0.0 0.0 GO:0060449 bud elongation involved in lung branching(GO:0060449)
0.0 0.0 GO:0010873 positive regulation of cholesterol esterification(GO:0010873)
0.0 0.0 GO:0006391 transcription initiation from mitochondrial promoter(GO:0006391)
0.0 0.1 GO:0031000 response to caffeine(GO:0031000)
0.0 0.0 GO:0021591 ventricular system development(GO:0021591)
0.0 0.0 GO:0080111 DNA demethylation(GO:0080111)
0.0 0.2 GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.0 0.0 GO:0071360 cellular response to exogenous dsRNA(GO:0071360)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.5 GO:0032449 CBM complex(GO:0032449)
0.0 0.1 GO:0005589 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.0 0.1 GO:0043259 laminin-10 complex(GO:0043259)
0.0 0.2 GO:0070688 MLL5-L complex(GO:0070688)
0.0 0.1 GO:0034363 intermediate-density lipoprotein particle(GO:0034363)
0.0 0.2 GO:0030127 COPII vesicle coat(GO:0030127)
0.0 0.1 GO:0030056 hemidesmosome(GO:0030056)
0.0 0.2 GO:0002102 podosome(GO:0002102)
0.0 0.2 GO:0005916 fascia adherens(GO:0005916)
0.0 0.1 GO:0031232 extrinsic component of external side of plasma membrane(GO:0031232)
0.0 0.1 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.0 0.1 GO:0005915 zonula adherens(GO:0005915)
0.0 0.1 GO:0005826 actomyosin contractile ring(GO:0005826)
0.0 0.1 GO:0031512 motile primary cilium(GO:0031512)
0.0 0.1 GO:0098642 network-forming collagen trimer(GO:0098642) collagen network(GO:0098645)
0.0 0.1 GO:0042629 mast cell granule(GO:0042629)
0.0 0.1 GO:0048179 activin receptor complex(GO:0048179)
0.0 0.3 GO:0016328 lateral plasma membrane(GO:0016328)
0.0 0.0 GO:0014704 intercalated disc(GO:0014704) cell-cell contact zone(GO:0044291)
0.0 0.4 GO:0005581 collagen trimer(GO:0005581)
0.0 0.0 GO:0071062 alphav-beta3 integrin-vitronectin complex(GO:0071062)
0.0 0.0 GO:0009331 glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.0 0.0 GO:1903561 extracellular exosome(GO:0070062) extracellular vesicle(GO:1903561)
0.0 0.1 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.0 0.0 GO:0033270 paranode region of axon(GO:0033270)
0.0 0.1 GO:0000137 Golgi cis cisterna(GO:0000137)
0.0 0.0 GO:0071664 catenin-TCF7L2 complex(GO:0071664)
0.0 0.1 GO:0005958 DNA-dependent protein kinase-DNA ligase 4 complex(GO:0005958)
0.0 0.1 GO:0005614 interstitial matrix(GO:0005614)
0.0 0.0 GO:0045254 pyruvate dehydrogenase complex(GO:0045254)
0.0 1.3 GO:0005925 focal adhesion(GO:0005925)
0.0 0.1 GO:0031095 platelet dense tubular network membrane(GO:0031095)
0.0 0.1 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.0 0.1 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.0 0.1 GO:0008091 spectrin(GO:0008091)
0.0 0.1 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.0 0.1 GO:0005858 axonemal dynein complex(GO:0005858)
0.0 0.0 GO:0000176 nuclear exosome (RNase complex)(GO:0000176)
0.0 0.0 GO:0001940 male pronucleus(GO:0001940)
0.0 0.1 GO:0031362 anchored component of external side of plasma membrane(GO:0031362)
0.0 0.2 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.0 0.1 GO:0035267 NuA4 histone acetyltransferase complex(GO:0035267)
0.0 0.1 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.0 0.1 GO:0009925 basal plasma membrane(GO:0009925)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0004095 carnitine O-palmitoyltransferase activity(GO:0004095) O-palmitoyltransferase activity(GO:0016416)
0.1 0.2 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.1 0.2 GO:0005030 neurotrophin receptor activity(GO:0005030)
0.0 0.1 GO:0050693 LBD domain binding(GO:0050693)
0.0 0.3 GO:0005172 vascular endothelial growth factor receptor binding(GO:0005172)
0.0 0.1 GO:0070324 thyroid hormone binding(GO:0070324)
0.0 0.1 GO:0047623 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.0 0.1 GO:0050501 hyaluronan synthase activity(GO:0050501)
0.0 0.1 GO:0070653 high-density lipoprotein particle receptor binding(GO:0070653)
0.0 0.1 GO:0015204 urea transmembrane transporter activity(GO:0015204)
0.0 0.1 GO:0060230 lipoprotein lipase activator activity(GO:0060230)
0.0 0.1 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.0 0.1 GO:0005010 insulin-like growth factor-activated receptor activity(GO:0005010)
0.0 0.1 GO:0043495 protein anchor(GO:0043495)
0.0 0.1 GO:0004616 phosphogluconate dehydrogenase (decarboxylating) activity(GO:0004616)
0.0 0.1 GO:0001159 RNA polymerase II core promoter proximal region sequence-specific DNA binding(GO:0000978) core promoter proximal region sequence-specific DNA binding(GO:0000987) core promoter proximal region DNA binding(GO:0001159)
0.0 0.1 GO:0042978 ornithine decarboxylase activator activity(GO:0042978)
0.0 0.1 GO:0045499 chemorepellent activity(GO:0045499)
0.0 0.6 GO:0005158 insulin receptor binding(GO:0005158)
0.0 0.1 GO:0004144 diacylglycerol O-acyltransferase activity(GO:0004144)
0.0 0.1 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.0 0.1 GO:0045159 myosin II binding(GO:0045159)
0.0 0.1 GO:0005432 calcium:sodium antiporter activity(GO:0005432)
0.0 0.1 GO:0016509 long-chain-3-hydroxyacyl-CoA dehydrogenase activity(GO:0016509)
0.0 0.0 GO:0070273 phosphatidylinositol-4-phosphate binding(GO:0070273)
0.0 0.1 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
0.0 0.1 GO:0097493 extracellular matrix constituent conferring elasticity(GO:0030023) structural molecule activity conferring elasticity(GO:0097493)
0.0 0.1 GO:0045294 alpha-catenin binding(GO:0045294)
0.0 0.3 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.0 0.1 GO:0031544 procollagen-proline 3-dioxygenase activity(GO:0019797) peptidyl-proline 3-dioxygenase activity(GO:0031544)
0.0 0.1 GO:0030618 transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity(GO:0030618)
0.0 0.1 GO:0030492 hemoglobin binding(GO:0030492)
0.0 0.1 GO:0004082 bisphosphoglycerate mutase activity(GO:0004082) bisphosphoglycerate 2-phosphatase activity(GO:0004083) phosphoglycerate mutase activity(GO:0004619)
0.0 0.2 GO:0071617 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841) lysophosphatidic acid acyltransferase activity(GO:0042171) lysophospholipid acyltransferase activity(GO:0071617)
0.0 0.1 GO:0042805 actinin binding(GO:0042805)
0.0 0.1 GO:0017166 vinculin binding(GO:0017166)
0.0 0.1 GO:0048027 mRNA 5'-UTR binding(GO:0048027)
0.0 0.1 GO:0019855 calcium channel inhibitor activity(GO:0019855)
0.0 0.1 GO:0004720 protein-lysine 6-oxidase activity(GO:0004720)
0.0 0.0 GO:0003680 AT DNA binding(GO:0003680)
0.0 0.0 GO:0004367 glycerol-3-phosphate dehydrogenase [NAD+] activity(GO:0004367)
0.0 0.0 GO:0004677 DNA-dependent protein kinase activity(GO:0004677)
0.0 0.1 GO:0030297 transmembrane receptor protein tyrosine kinase activator activity(GO:0030297)
0.0 0.0 GO:0035514 DNA demethylase activity(GO:0035514) DNA-N1-methyladenine dioxygenase activity(GO:0043734)
0.0 0.1 GO:0016361 activin receptor activity, type I(GO:0016361)
0.0 0.0 GO:0008184 glycogen phosphorylase activity(GO:0008184)
0.0 0.2 GO:0005123 death receptor binding(GO:0005123)
0.0 0.0 GO:0033130 acetylcholine receptor binding(GO:0033130)
0.0 0.1 GO:0008035 high-density lipoprotein particle binding(GO:0008035)
0.0 0.1 GO:0005110 frizzled-2 binding(GO:0005110)
0.0 0.1 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
0.0 0.0 GO:0050508 glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0050508)
0.0 0.1 GO:0015016 [heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
0.0 0.0 GO:0015252 hydrogen ion channel activity(GO:0015252)
0.0 0.1 GO:0001727 lipid kinase activity(GO:0001727)
0.0 0.1 GO:0004046 aminoacylase activity(GO:0004046)
0.0 0.0 GO:0004937 alpha1-adrenergic receptor activity(GO:0004937)
0.0 0.2 GO:0030159 receptor signaling complex scaffold activity(GO:0030159)
0.0 0.1 GO:0005143 interleukin-12 receptor binding(GO:0005143)
0.0 0.0 GO:0030151 molybdenum ion binding(GO:0030151)
0.0 0.0 GO:0004829 threonine-tRNA ligase activity(GO:0004829)
0.0 0.2 GO:0005523 tropomyosin binding(GO:0005523)
0.0 0.0 GO:0005017 platelet-derived growth factor-activated receptor activity(GO:0005017)
0.0 0.1 GO:0004652 polynucleotide adenylyltransferase activity(GO:0004652)
0.0 0.1 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.0 0.1 GO:0008409 5'-3' exonuclease activity(GO:0008409)
0.0 0.1 GO:0030506 ankyrin binding(GO:0030506)
0.0 0.2 GO:0005242 inward rectifier potassium channel activity(GO:0005242)
0.0 0.0 GO:0008934 inositol monophosphate 1-phosphatase activity(GO:0008934) inositol monophosphate phosphatase activity(GO:0052834)
0.0 0.1 GO:0015245 fatty acid transporter activity(GO:0015245)
0.0 0.0 GO:0005294 neutral L-amino acid secondary active transmembrane transporter activity(GO:0005294)
0.0 0.0 GO:0016453 C-acetyltransferase activity(GO:0016453)
0.0 0.0 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity(GO:0004694)
0.0 0.1 GO:0000014 single-stranded DNA endodeoxyribonuclease activity(GO:0000014)
0.0 0.0 GO:0016454 serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
0.0 0.0 GO:0004013 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.0 0.3 GO:0005272 sodium channel activity(GO:0005272)
0.0 0.8 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 0.0 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.0 0.7 GO:0005178 integrin binding(GO:0005178)
0.0 0.0 GO:0008607 phosphorylase kinase regulator activity(GO:0008607)
0.0 0.1 GO:0030332 cyclin binding(GO:0030332)
0.0 0.2 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 0.0 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.0 0.1 GO:0030274 LIM domain binding(GO:0030274)
0.0 0.1 GO:0017110 nucleoside-diphosphatase activity(GO:0017110)
0.0 0.1 GO:0016018 cyclosporin A binding(GO:0016018)
0.0 0.2 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding(GO:0005546)
0.0 0.1 GO:0016520 growth hormone-releasing hormone receptor activity(GO:0016520)
0.0 0.0 GO:0004157 dihydropyrimidinase activity(GO:0004157)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.0 ST INTERLEUKIN 4 PATHWAY Interleukin 4 (IL-4) Pathway
0.0 0.7 NABA COLLAGENS Genes encoding collagen proteins
0.0 0.2 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.0 0.2 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.0 0.0 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.0 0.5 PID ECADHERIN STABILIZATION PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.0 0.0 PID LPA4 PATHWAY LPA4-mediated signaling events
0.0 0.2 PID PI3K PLC TRK PATHWAY Trk receptor signaling mediated by PI3K and PLC-gamma
0.0 0.4 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.0 0.3 PID INTEGRIN3 PATHWAY Beta3 integrin cell surface interactions
0.0 0.2 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.4 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.0 0.3 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.0 0.4 REACTOME GAP JUNCTION ASSEMBLY Genes involved in Gap junction assembly
0.0 0.4 REACTOME ACTIVATED AMPK STIMULATES FATTY ACID OXIDATION IN MUSCLE Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle
0.0 0.3 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0 0.2 REACTOME SIGNALING BY ACTIVATED POINT MUTANTS OF FGFR1 Genes involved in Signaling by activated point mutants of FGFR1
0.0 0.2 REACTOME VITAMIN B5 PANTOTHENATE METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
0.0 0.3 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.0 0.4 REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.0 0.8 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.0 0.1 REACTOME FRS2 MEDIATED CASCADE Genes involved in FRS2-mediated cascade
0.0 0.0 REACTOME DAG AND IP3 SIGNALING Genes involved in DAG and IP3 signaling
0.0 0.0 REACTOME ADENYLATE CYCLASE INHIBITORY PATHWAY Genes involved in Adenylate cyclase inhibitory pathway
0.0 0.2 REACTOME RETROGRADE NEUROTROPHIN SIGNALLING Genes involved in Retrograde neurotrophin signalling
0.0 0.1 REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS Genes involved in Tandem pore domain potassium channels
0.0 0.1 REACTOME PURINE CATABOLISM Genes involved in Purine catabolism
0.0 0.1 REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.0 0.0 REACTOME TAK1 ACTIVATES NFKB BY PHOSPHORYLATION AND ACTIVATION OF IKKS COMPLEX Genes involved in TAK1 activates NFkB by phosphorylation and activation of IKKs complex
0.0 0.2 REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC