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ENCODE: H3K4me1 ChIP-Seq of primary human cells
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CREMA is a free online tool that recognizes most important transcription factors that change the chromatin state across different samples.

Results for NR4A2

Z-value: 0.74

Motif logo

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Transcription factors associated with NR4A2

Gene Symbol Gene ID Gene Info
NR4A2
ENSG00000153234.9 NR4A2

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE Gene Distance Association probability Pearson corr. coef. P-value Plot
NR4A2chr2_157177728_15717819086740.2769020.881.6e-03Click!
NR4A2chr2_157192385_15719259432570.3305140.872.4e-03Click!
NR4A2chr2_157200460_15720061116750.4627240.771.5e-02Click!
NR4A2chr2_157199362_1571995135770.8202740.684.2e-02Click!
NR4A2chr2_157191495_15719173123810.3844030.684.5e-02Click!

Activity of the NR4A2 motif across conditions

Conditions sorted by the z-value of the NR4A2 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE) Target Score Top associated gene Gene Info Distance of CRE to TSS CRE/Gene association probability
chr19_39369781_39369998 0.30 RINL
 Ras and Rab interactor-like
 970
 0.3
chr11_67173408_67173659 0.29 TBC1D10C
 TBC1 domain family, member 10C
 1873
 0.13
chr2_85546746_85546974 0.21 TGOLN2
 trans-golgi network protein 2
 8248
 0.1
chr19_10340265_10340416 0.20 ENSG00000264266
 .
 749
 0.37
chr3_46109007_46109236 0.20 XCR1
 chemokine (C motif) receptor 1
 39887
 0.15
chr17_47824865_47825302 0.18 FAM117A
 family with sequence similarity 117, member A
 16410
 0.14
chr21_16813564_16813819 0.17 ENSG00000212564
 .
 172911
 0.03
chr14_22974081_22974308 0.17 TRAJ51
 T cell receptor alpha joining 51 (pseudogene)
 18023
 0.09
chr13_100078305_100078553 0.16 ENSG00000266207
 .
 27294
 0.17
chr10_17469337_17469935 0.16 ST8SIA6-AS1
 ST8SIA6 antisense RNA 1
 19610
 0.17
chr3_46411260_46411477 0.16 CCR5
 chemokine (C-C motif) receptor 5 (gene/pseudogene)
 265
 0.9
chr13_30944981_30945174 0.16 KATNAL1
 katanin p60 subunit A-like 1
 63456
 0.13
chr13_41188423_41188902 0.16 FOXO1
 forkhead box O1
 52072
 0.14
chr16_68307091_68307362 0.16 SLC7A6
 solute carrier family 7 (amino acid transporter light chain, y+L system), member 6
 344
 0.72
chr7_142503382_142503602 0.16 PRSS3P2
 protease, serine, 3 pseudogene 2
 22361
 0.15
chr16_29036587_29036789 0.16 CTB-134H23.2
 Uncharacterized protein
 13235
 0.1
chr7_157112627_157112778 0.16 ENSG00000266453
 .
 14215
 0.22
chr1_175156305_175156626 0.15 KIAA0040
 KIAA0040
 5425
 0.29
chr3_16326802_16326964 0.15 OXNAD1
 oxidoreductase NAD-binding domain containing 1
 16135
 0.16
chr14_22966302_22966494 0.15 TRAJ51
 T cell receptor alpha joining 51 (pseudogene)
 10227
 0.1
chr3_32376993_32377254 0.15 CMTM7
 CKLF-like MARVEL transmembrane domain containing 7
 56040
 0.12
chr22_31680259_31680536 0.15 PIK3IP1
 phosphoinositide-3-kinase interacting protein 1
 7984
 0.11
chr4_110568848_110569074 0.15 AC004067.5
44199
 0.13
chr7_127749161_127749327 0.15 ENSG00000207588
 .
 27331
 0.2
chr2_158757598_158757749 0.15 ENSG00000251980
 .
 11611
 0.17
chr16_28504230_28504381 0.15 CLN3
 ceroid-lipofuscinosis, neuronal 3
 211
 0.88
chr2_43421170_43421346 0.15 ZFP36L2
 ZFP36 ring finger protein-like 2
 32490
 0.19
chr4_3198836_3199087 0.15 HTT
 huntingtin
 36872
 0.16
chr3_170965931_170966082 0.15 TNIK
 TRAF2 and NCK interacting kinase
 22506
 0.26
chr6_33873520_33874114 0.14 ENSG00000221697
 .
 94011
 0.06
chr2_136929632_136929822 0.14 CXCR4
 chemokine (C-X-C motif) receptor 4
 53992
 0.16
chr11_67173722_67173982 0.14 TBC1D10C
 TBC1 domain family, member 10C
 2192
 0.12
chr10_121052972_121053123 0.14 RP11-79M19.2
42647
 0.13
chr3_13388429_13388737 0.14 NUP210
 nucleoporin 210kDa
 73226
 0.11
chrX_48771847_48772324 0.14 PIM2
 pim-2 oncogene
 927
 0.37
chr11_128550606_128550867 0.14 RP11-744N12.3
5587
 0.19
chr19_42705324_42705478 0.14 ENSG00000265122
 .
 8171
 0.09
chr7_50206315_50206466 0.14 AC020743.2
23971
 0.21
chr5_142177966_142178152 0.14 ARHGAP26
 Rho GTPase activating protein 26
 25777
 0.22
chr8_126937126_126937461 0.14 ENSG00000206695
 .
 24098
 0.28
chr9_92083234_92083501 0.14 SEMA4D
 sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D
 11438
 0.23
chr8_27262728_27262897 0.14 PTK2B
 protein tyrosine kinase 2 beta
 7843
 0.23
chr16_79313034_79313388 0.14 ENSG00000222244
 .
 14860
 0.29
chr5_169700644_169700966 0.14 LCP2
 lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa)
 6474
 0.24
chr6_135437483_135437886 0.14 HBS1L
 HBS1-like (S. cerevisiae)
 13490
 0.21
chr19_19176974_19177125 0.14 SLC25A42
 solute carrier family 25, member 42
 2241
 0.21
chr5_133560624_133561078 0.14 PPP2CA
 protein phosphatase 2, catalytic subunit, alpha isozyme
 394
 0.54
chr7_99761629_99761818 0.14 GAL3ST4
 galactose-3-O-sulfotransferase 4
 3130
 0.09
chr3_33065751_33065902 0.14 GLB1
 galactosidase, beta 1
 72458
 0.08
chr6_52849862_52850203 0.13 ENSG00000252106
 .
 5979
 0.14
chrX_42259008_42259366 0.13 ENSG00000206896
 .
 225549
 0.02
chr6_149788780_149789048 0.13 ZC3H12D
 zinc finger CCCH-type containing 12D
 10909
 0.17
chr3_13931501_13932034 0.13 WNT7A
 wingless-type MMTV integration site family, member 7A
 10149
 0.22
chr6_167470313_167470474 0.13 CCR6
 chemokine (C-C motif) receptor 6
 54902
 0.09
chr2_205837401_205837570 0.13 PARD3B
 par-3 family cell polarity regulator beta
 426762
 0.01
chr16_23970957_23971112 0.13 PRKCB
 protein kinase C, beta
 122490
 0.05
chr14_62163629_62164039 0.13 HIF1A
 hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
 506
 0.84
chr2_191281890_191282188 0.13 MFSD6
 major facilitator superfamily domain containing 6
 8958
 0.2
chr17_37925720_37925871 0.13 IKZF3
 IKAROS family zinc finger 3 (Aiolos)
 8683
 0.13
chr14_98835450_98835601 0.13 ENSG00000241757
 .
 17524
 0.25
chr1_167451880_167452062 0.13 RP11-104L21.2
24073
 0.17
chr12_125094624_125094923 0.13 NCOR2
 nuclear receptor corepressor 2
 42763
 0.2
chr3_111263954_111264147 0.13 CD96
 CD96 molecule
 3053
 0.33
chr6_37480700_37480852 0.13 CCDC167
 coiled-coil domain containing 167
 13078
 0.2
chr18_56356435_56356586 0.13 RP11-126O1.4
11664
 0.15
chr2_204568946_204569184 0.13 CD28
 CD28 molecule
 2133
 0.4
chr16_28306148_28306299 0.13 SBK1
 SH3 domain binding kinase 1
 2383
 0.31
chr4_84132505_84132730 0.13 COQ2
 coenzyme Q2 4-hydroxybenzoate polyprenyltransferase
 73301
 0.1
chr7_1088786_1088941 0.13 GPR146
 G protein-coupled receptor 146
 4651
 0.11
chr1_167407962_167408153 0.13 RP11-104L21.2
19841
 0.19
chr16_89786830_89787010 0.13 ZNF276
 zinc finger protein 276
 112
 0.82
chr10_6216160_6216311 0.13 ENSG00000263628
 .
 22076
 0.13
chrX_56827923_56828117 0.13 ENSG00000204272
 .
 72328
 0.12
chr3_114011081_114011232 0.13 TIGIT
 T cell immunoreceptor with Ig and ITIM domains
 1207
 0.46
chr3_10435533_10435799 0.13 ENSG00000216135
 .
 580
 0.72
chr1_112137881_112138034 0.13 RAP1A
 RAP1A, member of RAS oncogene family
 24442
 0.14
chr18_67626471_67626784 0.13 CD226
 CD226 molecule
 2215
 0.43
chr12_12626467_12626673 0.13 DUSP16
 dual specificity phosphatase 16
 47489
 0.15
chr17_33408019_33408248 0.12 RFFL
 ring finger and FYVE-like domain containing E3 ubiquitin protein ligase
 7721
 0.1
chr11_118811573_118811791 0.12 ENSG00000239726
 .
 9762
 0.07
chr3_151972697_151972848 0.12 MBNL1
 muscleblind-like splicing regulator 1
 13057
 0.22
chr12_55372614_55372982 0.12 TESPA1
 thymocyte expressed, positive selection associated 1
 2824
 0.31
chr2_198079444_198079595 0.12 ANKRD44
 ankyrin repeat domain 44
 16757
 0.19
chr1_27945410_27945570 0.12 FGR
 feline Gardner-Rasheed sarcoma viral oncogene homolog
 5083
 0.16
chr3_113324939_113325090 0.12 ENSG00000265253
 .
 11291
 0.16
chr2_12851276_12851427 0.12 TRIB2
 tribbles pseudokinase 2
 5664
 0.28
chr10_8114025_8114267 0.12 GATA3
 GATA binding protein 3
 17377
 0.3
chr1_8594076_8594346 0.12 RERE
 arginine-glutamic acid dipeptide (RE) repeats
 8125
 0.23
chr5_150623515_150623785 0.12 GM2A
 GM2 ganglioside activator
 8803
 0.19
chr9_134588564_134588715 0.12 RAPGEF1
 Rap guanine nucleotide exchange factor (GEF) 1
 3410
 0.27
chr4_153025133_153025284 0.12 ENSG00000266244
 .
 124412
 0.05
chr3_113950412_113950563 0.12 ZNF80
 zinc finger protein 80
 5938
 0.18
chr6_107939877_107940028 0.12 RP1-67A8.3
107027
 0.06
chr13_24462987_24463158 0.12 C1QTNF9B-AS1
 C1QTNF9B antisense RNA 1
 44
 0.89
chr17_62102334_62102536 0.12 ICAM2
 intercellular adhesion molecule 2
 4441
 0.18
chr3_187696515_187696882 0.12 LPP
 LIM domain containing preferred translocation partner in lipoma
 174374
 0.03
chr5_54397274_54397694 0.12 GZMA
 granzyme A (granzyme 1, cytotoxic T-lymphocyte-associated serine esterase 3)
 992
 0.48
chr12_65061545_65061862 0.12 RP11-338E21.3
12904
 0.13
chr1_111436803_111436998 0.12 CD53
 CD53 molecule
 21124
 0.16
chr6_135424050_135424322 0.12 HBS1L
 HBS1-like (S. cerevisiae)
 8
 0.98
chr2_135425836_135426057 0.12 TMEM163
 transmembrane protein 163
 50624
 0.17
chr5_14708477_14709030 0.12 FAM105B
 family with sequence similarity 105, member B
 27094
 0.18
chr6_35703749_35704115 0.12 RP3-510O8.4
792
 0.37
chr13_30725272_30725600 0.12 ENSG00000266816
 .
 55400
 0.16
chr17_1618744_1618964 0.12 WDR81
 WD repeat domain 81
 963
 0.33
chr5_156615983_156616134 0.12 ITK
 IL2-inducible T-cell kinase
 8221
 0.13
chr5_156536818_156537126 0.12 HAVCR2
 hepatitis A virus cellular receptor 2
 247
 0.9
chr2_69726281_69726453 0.12 ENSG00000244236
 .
 17516
 0.18
chr4_48138223_48138476 0.12 TXK
 TXK tyrosine kinase
 2076
 0.28
chr8_144217530_144217702 0.12 LY6H
 lymphocyte antigen 6 complex, locus H
 23841
 0.15
chr1_226845432_226845670 0.12 ITPKB-IT1
 ITPKB intronic transcript 1 (non-protein coding)
 1820
 0.38
chrX_78513124_78513404 0.12 GPR174
 G protein-coupled receptor 174
 86795
 0.1
chr16_84588398_84588684 0.12 TLDC1
 TBC/LysM-associated domain containing 1
 902
 0.58
chr11_117917776_117917952 0.12 ENSG00000272075
 .
 20088
 0.14
chr3_170964865_170965129 0.12 TNIK
 TRAF2 and NCK interacting kinase
 21497
 0.26
chr13_74672570_74672721 0.12 KLF12
 Kruppel-like factor 12
 35749
 0.24
chr22_45065462_45065745 0.12 PRR5
 proline rich 5 (renal)
 1010
 0.59
chr1_32718399_32718550 0.12 LCK
 lymphocyte-specific protein tyrosine kinase
 1599
 0.2
chr12_67678878_67679038 0.12 CAND1
 cullin-associated and neddylation-dissociated 1
 13794
 0.32
chr14_99667806_99667957 0.12 AL162151.4
43128
 0.16
chr17_46517572_46517755 0.12 SKAP1
 src kinase associated phosphoprotein 1
 10082
 0.14
chr1_101586862_101587013 0.12 ENSG00000252765
 .
 11772
 0.2
chr1_145452601_145452808 0.12 TXNIP
 thioredoxin interacting protein
 13398
 0.1
chr19_50073795_50074168 0.12 ENSG00000207073
 .
 4052
 0.08
chr14_106454534_106454685 0.12 IGHV1-2
 immunoglobulin heavy variable 1-2
 1439
 0.13
chr22_40611796_40611947 0.12 TNRC6B
 trinucleotide repeat containing 6B
 37925
 0.18
chr5_156585974_156586125 0.12 MED7
 mediator complex subunit 7
 19
 0.97
chr6_154539920_154540071 0.12 IPCEF1
 interaction protein for cytohesin exchange factors 1
 27995
 0.26
chr1_100904323_100904474 0.12 RP5-837M10.4
47155
 0.13
chr17_19671401_19671617 0.12 ALDH3A1
 aldehyde dehydrogenase 3 family, member A1
 19253
 0.14
chr12_132859595_132859799 0.12 RP13-895J2.3
5762
 0.18
chr5_110087698_110087849 0.12 SLC25A46
 solute carrier family 25, member 46
 3047
 0.3
chr1_168391373_168391682 0.12 ENSG00000207974
 .
 46765
 0.16
chr21_43656036_43656459 0.12 ENSG00000223262
 .
 14964
 0.16
chr5_66477431_66477677 0.12 CD180
 CD180 molecule
 15073
 0.25
chr10_116300402_116300669 0.12 ABLIM1
 actin binding LIM protein 1
 13845
 0.26
chr7_8183723_8183874 0.12 ENSG00000265212
 .
 10854
 0.22
chr8_11059618_11059820 0.11 XKR6
 XK, Kell blood group complex subunit-related family, member 6
 844
 0.6
chr16_89793574_89793793 0.11 ZNF276
 zinc finger protein 276
 5731
 0.11
chr5_131335834_131336005 0.11 ACSL6
 acyl-CoA synthetase long-chain family member 6
 602
 0.65
chr12_105140593_105140744 0.11 ENSG00000222579
 .
 104934
 0.07
chr4_4420478_4420740 0.11 NSG1
 Homo sapiens neuron specific gene family member 1 (NSG1), transcript variant 3, mRNA.
 31777
 0.16
chr1_154318142_154318479 0.11 ENSG00000238365
 .
 7091
 0.11
chr2_240547319_240547470 0.11 AC079612.1
 Uncharacterized protein; cDNA FLJ45964 fis, clone PLACE7014396
 47399
 0.17
chr17_28085100_28085338 0.11 RP11-82O19.1
2902
 0.22
chr12_65054175_65054480 0.11 RP11-338E21.3
5528
 0.15
chr1_6214478_6214680 0.11 CHD5
 chromodomain helicase DNA binding protein 5
 25604
 0.13
chr17_43327159_43327310 0.11 CTD-2020K17.4
1031
 0.32
chr14_75988132_75988283 0.11 BATF
 basic leucine zipper transcription factor, ATF-like
 561
 0.77
chr2_204798430_204798581 0.11 ICOS
 inducible T-cell co-stimulator
 2966
 0.36
chr2_198189379_198189688 0.11 AC010746.3
13416
 0.15
chr10_52273044_52273229 0.11 RP11-512N4.2
40562
 0.15
chr2_97010635_97010786 0.11 NCAPH
 non-SMC condensin I complex, subunit H
 9154
 0.15
chr3_15503071_15503367 0.11 EAF1-AS1
 EAF1 antisense RNA 1
 10110
 0.12
chr16_75132336_75132487 0.11 ZNRF1
 zinc and ring finger 1, E3 ubiquitin protein ligase
 6271
 0.16
chr6_112132595_112132890 0.11 FYN
 FYN oncogene related to SRC, FGR, YES
 8539
 0.29
chr1_151809393_151809571 0.11 C2CD4D
 C2 calcium-dependent domain containing 4D
 3551
 0.1
chr15_22442785_22442936 0.11 IGHV1OR15-1
 immunoglobulin heavy variable 1/OR15-1 (non-functional)
 5959
 0.14
chr9_97374117_97374277 0.11 FBP2
 fructose-1,6-bisphosphatase 2
 18122
 0.2
chr22_40719217_40719484 0.11 ADSL
 adenylosuccinate lyase
 23157
 0.17
chr2_137038474_137038625 0.11 ENSG00000251976
 .
 109353
 0.07
chr1_24839011_24839397 0.11 RCAN3
 RCAN family member 3
 1606
 0.35
chr14_61874311_61874579 0.11 PRKCH
 protein kinase C, eta
 17033
 0.23
chr12_96492882_96493144 0.11 ENSG00000266889
 .
 3014
 0.27
chr13_30920007_30920231 0.11 KATNAL1
 katanin p60 subunit A-like 1
 38498
 0.19
chr2_7018864_7019040 0.11 RSAD2
 radical S-adenosyl methionine domain containing 2
 27
 0.98
chr2_213967890_213968041 0.11 IKZF2
 IKAROS family zinc finger 2 (Helios)
 45388
 0.18
chr19_35946553_35946707 0.11 FFAR2
 free fatty acid receptor 2
 6013
 0.12
chr6_45937775_45937926 0.11 CLIC5
 chloride intracellular channel 5
 45715
 0.16
chr19_42144419_42144587 0.11 CEACAM4
 carcinoembryonic antigen-related cell adhesion molecule 4
 11061
 0.14
chr1_32728308_32728610 0.11 LCK
 lymphocyte-specific protein tyrosine kinase
 11255
 0.09
chr7_37472600_37472809 0.11 ENSG00000201566
 .
 2014
 0.32
chr11_2484360_2484511 0.11 KCNQ1
 potassium voltage-gated channel, KQT-like subfamily, member 1
 1318
 0.41
chr16_75662599_75662750 0.11 ADAT1
 adenosine deaminase, tRNA-specific 1
 5476
 0.15
chr7_2755301_2755475 0.11 AMZ1
 archaelysin family metallopeptidase 1
 27552
 0.17
chr10_62537751_62537923 0.11 CDK1
 cyclin-dependent kinase 1
 252
 0.95
chr4_6919752_6920098 0.11 TBC1D14
 TBC1 domain family, member 14
 7950
 0.19
chr16_57076661_57076948 0.11 NLRC5
 NLR family, CARD domain containing 5
 15173
 0.13
chr5_65440945_65441096 0.11 SREK1
 splicing regulatory glutamine/lysine-rich protein 1
 357
 0.52
chr10_130834166_130834339 0.11 MGMT
 O-6-methylguanine-DNA methyltransferase
 431196
 0.01
chr1_228073251_228073501 0.11 ENSG00000264483
 .
 56008
 0.1
chr6_37016131_37016432 0.11 COX6A1P2
 cytochrome c oxidase subunit VIa polypeptide 1 pseudogene 2
 3674
 0.24
chr1_226914487_226914750 0.11 ITPKB
 inositol-trisphosphate 3-kinase B
 10541
 0.23
chr11_120950309_120950460 0.11 TECTA
 tectorin alpha
 21498
 0.23
chr2_109579399_109579550 0.11 EDAR
 ectodysplasin A receptor
 26251
 0.24
chr3_111854444_111854779 0.11 RP11-757F18.5
2341
 0.24
chr17_38251187_38251338 0.11 NR1D1
 nuclear receptor subfamily 1, group D, member 1
 5716
 0.13
chr6_41933651_41933802 0.11 CCND3
 cyclin D3
 24140
 0.12
chr14_99723564_99723715 0.11 AL109767.1
5646
 0.23
chr1_59388452_59388603 0.11 JUN
 jun proto-oncogene
 138742
 0.05
chr5_131347971_131348122 0.11 ACSL6
 acyl-CoA synthetase long-chain family member 6
 176
 0.88
chr6_34620373_34620524 0.11 C6orf106
 chromosome 6 open reading frame 106
 19285
 0.13
chr3_150292423_150292574 0.11 EIF2A
 eukaryotic translation initiation factor 2A, 65kDa
 6679
 0.2
chr5_139081202_139081366 0.11 ENSG00000200756
 .
 16391
 0.19
chr9_92100956_92101114 0.11 SEMA4D
 sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D
 6230
 0.24
chr10_6631757_6631908 0.11 PRKCQ
 protein kinase C, theta
 9569
 0.31
chr9_96707778_96707942 0.11 BARX1
 BARX homeobox 1
 7853
 0.27
chr14_69238852_69239003 0.11 ZFP36L1
 ZFP36 ring finger protein-like 1
 19033
 0.19
chr9_117136205_117136760 0.11 AKNA
 AT-hook transcription factor
 2762
 0.28
chr1_90117224_90117495 0.11 LRRC8C
 leucine rich repeat containing 8 family, member C
 18728
 0.16

Histogram of CRE-TSS distances for CREs targeted by :

Histogram of

Rank distribution of CRE target scores:

Histogram of target CRE score.

Distribution of target CREs across different genomic regions:

Weighted Piechart of Weighted Piechart of Weighted Piechart of

Network of associatons between targets according to the STRING database.

StringDB image

First level regulatory network of NR4A2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0016242 negative regulation of macroautophagy(GO:0016242)
0.0 0.1 GO:0060394 negative regulation of pathway-restricted SMAD protein phosphorylation(GO:0060394)
0.0 0.1 GO:0097709 connective tissue replacement involved in inflammatory response wound healing(GO:0002248) connective tissue replacement(GO:0097709)
0.0 0.1 GO:0090224 regulation of spindle organization(GO:0090224)
0.0 0.1 GO:0002677 negative regulation of chronic inflammatory response(GO:0002677)
0.0 0.1 GO:0034501 protein localization to kinetochore(GO:0034501)
0.0 0.1 GO:0042518 negative regulation of tyrosine phosphorylation of Stat3 protein(GO:0042518)
0.0 0.0 GO:0048304 positive regulation of isotype switching to IgG isotypes(GO:0048304)
0.0 0.1 GO:0060295 regulation of cilium movement(GO:0003352) regulation of cilium beat frequency(GO:0003356) cilium movement involved in cell motility(GO:0060294) regulation of cilium movement involved in cell motility(GO:0060295) regulation of cilium beat frequency involved in ciliary motility(GO:0060296) regulation of cilium-dependent cell motility(GO:1902019)
0.0 0.2 GO:0007172 signal complex assembly(GO:0007172)
0.0 0.1 GO:0042091 interleukin-10 biosynthetic process(GO:0042091) regulation of interleukin-10 biosynthetic process(GO:0045074)
0.0 0.1 GO:0006922 obsolete cleavage of lamin involved in execution phase of apoptosis(GO:0006922)
0.0 0.1 GO:0045066 regulatory T cell differentiation(GO:0045066)
0.0 0.1 GO:0048312 intracellular distribution of mitochondria(GO:0048312)
0.0 0.1 GO:0007256 activation of JNKK activity(GO:0007256)
0.0 0.1 GO:0010831 positive regulation of myotube differentiation(GO:0010831)
0.0 0.1 GO:0032836 glomerular basement membrane development(GO:0032836)
0.0 0.1 GO:0017183 peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183)
0.0 0.1 GO:0045898 regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045898)
0.0 0.1 GO:0061298 retina vasculature development in camera-type eye(GO:0061298) retina vasculature morphogenesis in camera-type eye(GO:0061299)
0.0 0.1 GO:0006089 lactate metabolic process(GO:0006089)
0.0 0.1 GO:1901341 activation of store-operated calcium channel activity(GO:0032237) regulation of store-operated calcium channel activity(GO:1901339) positive regulation of store-operated calcium channel activity(GO:1901341)
0.0 0.0 GO:0030223 neutrophil differentiation(GO:0030223)
0.0 0.0 GO:0001574 ganglioside biosynthetic process(GO:0001574)
0.0 0.0 GO:0010761 fibroblast migration(GO:0010761)
0.0 0.0 GO:0016137 glycoside metabolic process(GO:0016137) glycoside catabolic process(GO:0016139)
0.0 0.1 GO:0042149 cellular response to glucose starvation(GO:0042149)
0.0 0.0 GO:0007132 meiotic metaphase I(GO:0007132)
0.0 0.0 GO:0045722 positive regulation of gluconeogenesis(GO:0045722)
0.0 0.1 GO:0002710 negative regulation of T cell mediated immunity(GO:0002710)
0.0 0.0 GO:0048302 regulation of isotype switching to IgG isotypes(GO:0048302)
0.0 0.0 GO:0048263 determination of dorsal identity(GO:0048263)
0.0 0.1 GO:0032695 negative regulation of interleukin-12 production(GO:0032695)
0.0 0.1 GO:0002726 positive regulation of T cell cytokine production(GO:0002726)
0.0 0.1 GO:0006538 glutamate catabolic process(GO:0006538)
0.0 0.1 GO:0021999 neural plate anterior/posterior regionalization(GO:0021999) neural plate regionalization(GO:0060897)
0.0 0.1 GO:0010508 positive regulation of autophagy(GO:0010508)
0.0 0.0 GO:0031063 regulation of histone deacetylation(GO:0031063)
0.0 0.2 GO:0019059 obsolete initiation of viral infection(GO:0019059)
0.0 0.1 GO:0048096 chromatin-mediated maintenance of transcription(GO:0048096)
0.0 0.1 GO:0022417 protein maturation by protein folding(GO:0022417)
0.0 0.1 GO:0035434 copper ion transmembrane transport(GO:0035434)
0.0 0.1 GO:0002836 regulation of response to tumor cell(GO:0002834) positive regulation of response to tumor cell(GO:0002836) regulation of immune response to tumor cell(GO:0002837) positive regulation of immune response to tumor cell(GO:0002839)
0.0 0.0 GO:0031125 rRNA 3'-end processing(GO:0031125)
0.0 0.1 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.0 0.1 GO:0006657 CDP-choline pathway(GO:0006657)
0.0 0.1 GO:0006474 N-terminal protein amino acid acetylation(GO:0006474)
0.0 0.0 GO:0044240 multicellular organism lipid catabolic process(GO:0044240)
0.0 0.1 GO:0006000 fructose metabolic process(GO:0006000)
0.0 0.0 GO:0051573 negative regulation of histone H3-K9 methylation(GO:0051573)
0.0 0.0 GO:0009313 oligosaccharide catabolic process(GO:0009313)
0.0 0.2 GO:0035336 long-chain fatty-acyl-CoA metabolic process(GO:0035336) long-chain fatty-acyl-CoA biosynthetic process(GO:0035338)
0.0 0.0 GO:0071699 olfactory placode formation(GO:0030910) olfactory placode development(GO:0071698) olfactory placode morphogenesis(GO:0071699)
0.0 0.0 GO:0002691 regulation of cellular extravasation(GO:0002691)
0.0 0.0 GO:0060766 negative regulation of androgen receptor signaling pathway(GO:0060766)
0.0 0.1 GO:0042989 sequestering of actin monomers(GO:0042989)
0.0 0.1 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.0 0.1 GO:0032784 regulation of DNA-templated transcription, elongation(GO:0032784)
0.0 0.1 GO:0045059 positive thymic T cell selection(GO:0045059)
0.0 0.1 GO:0018106 peptidyl-histidine phosphorylation(GO:0018106) peptidyl-histidine modification(GO:0018202)
0.0 0.1 GO:0006491 N-glycan processing(GO:0006491)
0.0 0.0 GO:0033152 immunoglobulin V(D)J recombination(GO:0033152)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0031264 death-inducing signaling complex(GO:0031264)
0.0 0.1 GO:0001652 granular component(GO:0001652)
0.0 0.4 GO:0005776 autophagosome(GO:0005776)
0.0 0.1 GO:0005826 actomyosin contractile ring(GO:0005826)
0.0 0.0 GO:0048179 activin receptor complex(GO:0048179)
0.0 0.1 GO:0000796 condensin complex(GO:0000796)
0.0 0.1 GO:0045275 mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
0.0 0.1 GO:0042597 outer membrane-bounded periplasmic space(GO:0030288) periplasmic space(GO:0042597)
0.0 0.1 GO:0031088 platelet dense granule membrane(GO:0031088)
0.0 0.1 GO:0072357 PTW/PP1 phosphatase complex(GO:0072357)
0.0 0.0 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)
0.0 0.1 GO:0005742 mitochondrial outer membrane translocase complex(GO:0005742)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0042156 obsolete zinc-mediated transcriptional activator activity(GO:0042156)
0.0 0.1 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
0.0 0.1 GO:0004351 glutamate decarboxylase activity(GO:0004351)
0.0 0.2 GO:0034713 type I transforming growth factor beta receptor binding(GO:0034713)
0.0 0.1 GO:0015925 galactosidase activity(GO:0015925)
0.0 0.2 GO:0016493 C-C chemokine receptor activity(GO:0016493)
0.0 0.1 GO:0004331 fructose-2,6-bisphosphate 2-phosphatase activity(GO:0004331)
0.0 0.1 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.0 0.1 GO:0005025 transforming growth factor beta receptor activity, type I(GO:0005025)
0.0 0.1 GO:0034481 chondroitin sulfotransferase activity(GO:0034481)
0.0 0.0 GO:0030375 thyroid hormone receptor coactivator activity(GO:0030375)
0.0 0.1 GO:0019992 diacylglycerol binding(GO:0019992)
0.0 0.0 GO:0004477 methenyltetrahydrofolate cyclohydrolase activity(GO:0004477)
0.0 0.0 GO:0003953 NAD+ nucleosidase activity(GO:0003953)
0.0 0.2 GO:0051879 Hsp90 protein binding(GO:0051879)
0.0 0.1 GO:0050811 GABA receptor binding(GO:0050811)
0.0 0.1 GO:0016417 S-acyltransferase activity(GO:0016417)
0.0 0.1 GO:0004467 long-chain fatty acid-CoA ligase activity(GO:0004467)
0.0 0.0 GO:0031177 phosphopantetheine binding(GO:0031177)
0.0 0.0 GO:0047894 flavonol 3-sulfotransferase activity(GO:0047894)
0.0 0.0 GO:0016909 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.0 0.1 GO:0005375 copper ion transmembrane transporter activity(GO:0005375)
0.0 0.0 GO:0033691 sialic acid binding(GO:0033691)
0.0 0.1 GO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.0 0.0 GO:0055103 ligase regulator activity(GO:0055103) ubiquitin-protein transferase regulator activity(GO:0055106)
0.0 0.1 GO:0016494 C-X-C chemokine receptor activity(GO:0016494)
0.0 0.0 GO:0016309 1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
0.0 0.1 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.0 0.1 GO:0016833 oxo-acid-lyase activity(GO:0016833)
0.0 0.0 GO:0019788 NEDD8 transferase activity(GO:0019788)
0.0 0.1 GO:0015271 outward rectifier potassium channel activity(GO:0015271)
0.0 0.1 GO:0003711 obsolete transcription elongation regulator activity(GO:0003711)
0.0 0.1 GO:0016290 palmitoyl-CoA hydrolase activity(GO:0016290)
0.0 0.0 GO:0016004 phospholipase activator activity(GO:0016004)
0.0 0.0 GO:0008853 exodeoxyribonuclease III activity(GO:0008853)
0.0 0.0 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.0 0.1 GO:0005112 Notch binding(GO:0005112)
0.0 0.1 GO:0005131 growth hormone receptor binding(GO:0005131)
0.0 0.0 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454)
0.0 0.1 GO:0070742 C2H2 zinc finger domain binding(GO:0070742)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.0 PID S1P S1P1 PATHWAY S1P1 pathway
0.0 0.2 SA FAS SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.0 0.0 PID IL8 CXCR1 PATHWAY IL8- and CXCR1-mediated signaling events
0.0 0.2 PID TCR JNK PATHWAY JNK signaling in the CD4+ TCR pathway
0.0 0.1 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.0 0.5 PID TCR PATHWAY TCR signaling in naïve CD4+ T cells

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 REACTOME BINDING AND ENTRY OF HIV VIRION Genes involved in Binding and entry of HIV virion
0.0 0.2 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.0 0.2 REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.0 0.1 REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.0 0.1 REACTOME CD28 DEPENDENT VAV1 PATHWAY Genes involved in CD28 dependent Vav1 pathway
0.0 0.1 REACTOME RAF MAP KINASE CASCADE Genes involved in RAF/MAP kinase cascade
0.0 0.1 REACTOME ERKS ARE INACTIVATED Genes involved in ERKs are inactivated
0.0 0.3 REACTOME TGF BETA RECEPTOR SIGNALING ACTIVATES SMADS Genes involved in TGF-beta receptor signaling activates SMADs