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ENCODE: H3K4me1 ChIP-Seq of primary human cells
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CREMA is a free online tool that recognizes most important transcription factors that change the chromatin state across different samples.

Results for NR5A2

Z-value: 0.81

Motif logo

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Transcription factors associated with NR5A2

Gene Symbol Gene ID Gene Info
NR5A2
ENSG00000116833.9 NR5A2

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE Gene Distance Association probability Pearson corr. coef. P-value Plot
NR5A2chr1_199998359_19999878615610.362802-0.844.6e-03Click!
NR5A2chr1_200010858_2000110097840.625387-0.791.2e-02Click!
NR5A2chr1_200011513_2000116641290.960054-0.791.2e-02Click!
NR5A2chr1_200007321_20000747243210.202584-0.781.3e-02Click!
NR5A2chr1_200008137_20000828835050.219220-0.761.8e-02Click!

Activity of the NR5A2 motif across conditions

Conditions sorted by the z-value of the NR5A2 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE) Target Score Top associated gene Gene Info Distance of CRE to TSS CRE/Gene association probability
chr11_116705965_116706733 0.51 APOA1-AS
 APOA1 antisense RNA
 484
 0.63
chr19_4063421_4064204 0.31 CTD-2622I13.3
1065
 0.34
chr15_75082253_75083502 0.29 ENSG00000264386
 .
 1779
 0.21
chr6_108019813_108020038 0.25 SCML4
 sex comb on midleg-like 4 (Drosophila)
 33674
 0.22
chr3_38071955_38072561 0.25 PLCD1
 phospholipase C, delta 1
 1005
 0.45
chr5_138288736_138289663 0.24 CTNNA1
 catenin (cadherin-associated protein), alpha 1, 102kDa
 22872
 0.17
chr17_79070617_79071314 0.23 BAIAP2
 BAI1-associated protein 2
 414
 0.74
chr16_88518586_88519370 0.23 ZFPM1
 zinc finger protein, FOG family member 1
 747
 0.63
chr3_158506187_158506338 0.22 RP11-379F4.8
5926
 0.17
chr1_85786366_85786652 0.22 ENSG00000264380
 .
 36216
 0.12
chr9_96720941_96721916 0.21 BARX1
 BARX homeobox 1
 3774
 0.31
chr19_1168901_1169806 0.20 SBNO2
 strawberry notch homolog 2 (Drosophila)
 411
 0.76
chr2_33294539_33294812 0.18 LTBP1
 latent transforming growth factor beta binding protein 1
 64798
 0.12
chr14_21443520_21443671 0.18 ENSG00000243817
 .
 11857
 0.09
chr6_52410307_52410659 0.18 TRAM2
 translocation associated membrane protein 2
 31230
 0.2
chr3_127489738_127489889 0.18 MGLL
 monoglyceride lipase
 13038
 0.24
chr19_40698237_40698804 0.17 MAP3K10
 mitogen-activated protein kinase kinase kinase 10
 869
 0.47
chr6_108013870_108014021 0.17 SCML4
 sex comb on midleg-like 4 (Drosophila)
 39654
 0.2
chr15_40339457_40340106 0.17 SRP14
 signal recognition particle 14kDa (homologous Alu RNA binding protein)
 8392
 0.16
chr9_136858320_136859229 0.17 VAV2
 vav 2 guanine nucleotide exchange factor
 1048
 0.54
chr8_49383721_49383872 0.17 RP11-770E5.1
80331
 0.11
chr7_1571328_1572335 0.17 MAFK
 v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog K
 1481
 0.33
chr8_23018463_23019142 0.16 TNFRSF10D
 tumor necrosis factor receptor superfamily, member 10d, decoy with truncated death domain
 2741
 0.2
chr5_171571507_171572131 0.16 STK10
 serine/threonine kinase 10
 43571
 0.13
chr2_71971317_71971468 0.16 DYSF
 dysferlin
 277560
 0.01
chr15_60671550_60671832 0.16 ANXA2
 annexin A2
 4987
 0.3
chr19_45755493_45756253 0.16 MARK4
 MAP/microtubule affinity-regulating kinase 4
 1323
 0.34
chr7_18895489_18895640 0.16 AC004744.3
43492
 0.17
chr20_61808362_61808898 0.16 ENSG00000207598
 .
 1222
 0.4
chr19_1513130_1513873 0.16 ADAMTSL5
 ADAMTS-like 5
 313
 0.73
chr11_9024402_9025454 0.16 NRIP3
 nuclear receptor interacting protein 3
 620
 0.45
chr11_86286039_86286190 0.16 ME3
 malic enzyme 3, NADP(+)-dependent, mitochondrial
 15252
 0.28
chr16_4378324_4378965 0.15 GLIS2
 GLIS family zinc finger 2
 3581
 0.16
chr8_42052948_42053131 0.15 PLAT
 plasminogen activator, tissue
 177
 0.94
chr1_168391373_168391682 0.15 ENSG00000207974
 .
 46765
 0.16
chr20_48924751_48924985 0.15 CEBPB
 CCAAT/enhancer binding protein (C/EBP), beta
 117492
 0.05
chr18_43533746_43533940 0.15 EPG5
 ectopic P-granules autophagy protein 5 homolog (C. elegans)
 13397
 0.21
chr4_153894531_153894682 0.15 FHDC1
 FH2 domain containing 1
 30471
 0.21
chr19_1324652_1325370 0.15 MUM1
 melanoma associated antigen (mutated) 1
 29699
 0.07
chr5_133461389_133462125 0.15 TCF7
 transcription factor 7 (T-cell specific, HMG-box)
 2448
 0.32
chr16_575840_576693 0.15 CAPN15
 calpain 15
 1451
 0.21
chr20_62489450_62490189 0.15 ABHD16B
 abhydrolase domain containing 16B
 2747
 0.11
chr9_116987434_116987585 0.15 ENSG00000207726
 .
 15795
 0.21
chr11_9787694_9787845 0.15 SBF2-AS1
 SBF2 antisense RNA 1
 7926
 0.18
chr16_79732631_79732782 0.15 ENSG00000221330
 .
 29072
 0.25
chr4_40550509_40550660 0.15 RBM47
 RNA binding motif protein 47
 32594
 0.17
chr2_19323725_19323876 0.15 ENSG00000266738
 .
 224390
 0.02
chr6_24831675_24831826 0.15 ENSG00000263391
 .
 8543
 0.17
chr5_112417198_112417349 0.15 DCP2
 decapping mRNA 2
 104794
 0.06
chr3_99743571_99743722 0.14 ENSG00000264897
 .
 60404
 0.12
chr14_103986978_103987655 0.14 CKB
 creatine kinase, brain
 122
 0.92
chr17_41141435_41141586 0.14 ENSG00000200127
 .
 8514
 0.07
chr16_80307065_80307216 0.14 DYNLRB2
 dynein, light chain, roadblock-type 2
 267491
 0.02
chr19_18596855_18597476 0.14 ELL
 elongation factor RNA polymerase II
 10422
 0.1
chr10_112201813_112201964 0.14 ENSG00000221359
 .
 7889
 0.21
chr1_56183531_56183682 0.14 PIGQP1
 phosphatidylinositol glycan anchor biosynthesis, class Q pseudogene 1
 221347
 0.02
chr22_36748127_36749442 0.14 MYH9
 myosin, heavy chain 9, non-muscle
 12372
 0.18
chr2_152191078_152191290 0.14 TNFAIP6
 tumor necrosis factor, alpha-induced protein 6
 22922
 0.15
chr20_60878742_60879796 0.14 ADRM1
 adhesion regulating molecule 1
 1208
 0.33
chr2_74755282_74756348 0.14 HTRA2
 HtrA serine peptidase 2
 689
 0.35
chr11_128380229_128380812 0.14 ETS1
 v-ets avian erythroblastosis virus E26 oncogene homolog 1
 5231
 0.26
chr2_239593817_239593968 0.14 TWIST2
 twist family bHLH transcription factor 2
 162781
 0.03
chr7_134395349_134395531 0.14 CALD1
 caldesmon 1
 33563
 0.19
chr12_54626263_54626414 0.14 ENSG00000265371
 .
 1078
 0.33
chr1_7530818_7530969 0.14 RP4-549F15.1
29279
 0.21
chr17_13488269_13488420 0.14 HS3ST3A1
 heparan sulfate (glucosamine) 3-O-sulfotransferase 3A1
 16900
 0.23
chr4_7893029_7893233 0.14 AFAP1
 actin filament associated protein 1
 19091
 0.21
chr3_16166790_16167040 0.14 GALNT15
 UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 15
 49241
 0.16
chr6_76147282_76147433 0.14 ENSG00000263533
 .
 9234
 0.18
chr15_39425151_39425407 0.14 RP11-624L4.1
14365
 0.29
chr7_127743675_127744013 0.14 ENSG00000207588
 .
 21931
 0.21
chr15_67055010_67055873 0.14 SMAD6
 SMAD family member 6
 51406
 0.15
chr1_16277969_16279055 0.14 ZBTB17
 zinc finger and BTB domain containing 17
 7589
 0.15
chr12_90284221_90284372 0.14 ENSG00000252823
 .
 136460
 0.05
chr17_38631919_38632290 0.14 TNS4
 tensin 4
 2796
 0.22
chr11_120581388_120581539 0.14 GRIK4
 glutamate receptor, ionotropic, kainate 4
 146320
 0.04
chr8_126557395_126557546 0.14 ENSG00000266452
 .
 100663
 0.08
chr11_63994452_63995293 0.14 NUDT22
 nudix (nucleoside diphosphate linked moiety X)-type motif 22
 791
 0.28
chr3_187952552_187952703 0.14 LPP
 LIM domain containing preferred translocation partner in lipoma
 5025
 0.29
chr14_52142402_52142553 0.13 ENSG00000251756
 .
 16993
 0.17
chr1_36824449_36824600 0.13 STK40
 serine/threonine kinase 40
 2417
 0.21
chr6_393086_393625 0.13 IRF4
 interferon regulatory factor 4
 1616
 0.51
chr3_134082413_134082992 0.13 AMOTL2
 angiomotin like 2
 8052
 0.23
chr6_169367816_169367967 0.13 XXyac-YX65C7_A.2
245458
 0.02
chr13_42188337_42188488 0.13 ENSG00000264190
 .
 45881
 0.17
chr20_39387092_39387243 0.13 MAFB
 v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B
 69287
 0.13
chr7_155048855_155049006 0.13 INSIG1
 insulin induced gene 1
 40556
 0.14
chr2_8309266_8309440 0.13 AC011747.7
506543
 0.0
chr17_983655_983915 0.13 ABR
 active BCR-related
 1399
 0.45
chr10_27220222_27220564 0.13 ENSG00000238414
 .
 63299
 0.1
chr5_133889727_133890225 0.13 JADE2
 jade family PHD finger 2
 27649
 0.13
chr6_3869542_3869744 0.13 FAM50B
 family with sequence similarity 50, member B
 20021
 0.19
chr1_201672579_201672730 0.13 ENSG00000264802
 .
 15982
 0.13
chr5_54457577_54457728 0.13 GPX8
 glutathione peroxidase 8 (putative)
 1654
 0.24
chr5_40226013_40226164 0.13 ENSG00000199361
 .
 43572
 0.2
chr13_50592048_50592199 0.13 KCNRG
 potassium channel regulator
 2733
 0.19
chr16_66960728_66960938 0.13 RRAD
 Ras-related associated with diabetes
 1286
 0.28
chr11_12821990_12822259 0.13 RP11-47J17.3
23090
 0.19
chr5_115275947_115276098 0.13 AQPEP
 Aminopeptidase Q
 22129
 0.18
chr5_139557667_139557868 0.13 CYSTM1
 cysteine-rich transmembrane module containing 1
 3540
 0.18
chr17_3461772_3461958 0.13 TRPV3
 transient receptor potential cation channel, subfamily V, member 3
 576
 0.64
chr1_3465027_3465178 0.13 ENSG00000207776
 .
 12252
 0.16
chr22_20904853_20905469 0.13 MED15
 mediator complex subunit 15
 113
 0.95
chr11_68023958_68024109 0.13 C11orf24
 chromosome 11 open reading frame 24
 15382
 0.19
chr17_59371887_59372038 0.13 RP11-332H18.3
88184
 0.07
chrX_20505644_20505795 0.12 ENSG00000252978
 .
 35493
 0.23
chr12_76175007_76175158 0.12 ENSG00000264062
 .
 56761
 0.14
chr2_121316540_121316691 0.12 ENSG00000201006
 .
 92234
 0.08
chr11_65687695_65688595 0.12 DRAP1
 DR1-associated protein 1 (negative cofactor 2 alpha)
 950
 0.31
chr17_63980854_63981005 0.12 CEP112
 centrosomal protein 112kDa
 85133
 0.11
chr5_60921647_60922495 0.12 C5orf64
 chromosome 5 open reading frame 64
 11565
 0.22
chr2_284941_285092 0.12 ENSG00000228643
 .
 1551
 0.31
chr15_31630334_31631466 0.12 KLF13
 Kruppel-like factor 13
 1236
 0.62
chr5_178692104_178692462 0.12 ADAMTS2
 ADAM metallopeptidase with thrombospondin type 1 motif, 2
 80148
 0.1
chr3_33868027_33868178 0.12 PDCD6IP
 programmed cell death 6 interacting protein
 27987
 0.25
chr1_183820208_183820359 0.12 RGL1
 ral guanine nucleotide dissociation stimulator-like 1
 45993
 0.16
chr11_27206625_27206776 0.12 RP11-1L12.3
33582
 0.22
chr1_15480447_15481131 0.12 TMEM51
 transmembrane protein 51
 504
 0.82
chr17_72056636_72056787 0.12 RPL38
 ribosomal protein L38
 143010
 0.04
chr11_12011920_12012071 0.12 DKK3
 dickkopf WNT signaling pathway inhibitor 3
 18135
 0.26
chr3_52256014_52256708 0.12 TLR9
 toll-like receptor 9
 3818
 0.12
chr9_136821628_136822276 0.12 VAV2
 vav 2 guanine nucleotide exchange factor
 35451
 0.17
chr7_134105016_134105167 0.12 AKR1B1
 aldo-keto reductase family 1, member B1 (aldose reductase)
 38803
 0.18
chr11_6716702_6716921 0.12 MRPL17
 mitochondrial ribosomal protein L17
 12179
 0.11
chr14_56381140_56381291 0.12 ENSG00000212522
 .
 153946
 0.04
chr2_87552860_87553169 0.12 IGKV3OR2-268
 immunoglobulin kappa variable 3/OR2-268 (non-functional)
 12620
 0.29
chr15_79935912_79936063 0.12 ENSG00000252995
 .
 173805
 0.03
chr3_48508143_48509126 0.12 TREX1
 three prime repair exonuclease 1
 973
 0.34
chr3_188242521_188242672 0.12 LPP-AS1
 LPP antisense RNA 1
 43858
 0.18
chr22_38614803_38615828 0.12 MAFF
 v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
 5773
 0.12
chr5_134490982_134491133 0.12 PITX1
 paired-like homeodomain 1
 120554
 0.05
chr12_13052986_13053183 0.12 GPRC5A
 G protein-coupled receptor, family C, group 5, member A
 8176
 0.14
chr1_7284324_7284475 0.12 ENSG00000207056
 .
 4979
 0.32
chr1_92344193_92344344 0.12 TGFBR3
 transforming growth factor, beta receptor III
 7398
 0.23
chr20_61283602_61284308 0.12 SLCO4A1
 solute carrier organic anion transporter family, member 4A1
 3756
 0.14
chr7_24741561_24741712 0.12 DFNA5
 deafness, autosomal dominant 5
 4209
 0.34
chr1_54083474_54083625 0.12 ENSG00000239007
 .
 70936
 0.1
chr12_57175860_57176011 0.12 HSD17B6
 hydroxysteroid (17-beta) dehydrogenase 6
 18827
 0.14
chr6_39789916_39790103 0.12 DAAM2
 dishevelled associated activator of morphogenesis 2
 26333
 0.21
chr5_133206314_133206465 0.12 ENSG00000238796
 .
 19741
 0.25
chr11_11994844_11994995 0.12 DKK3
 dickkopf WNT signaling pathway inhibitor 3
 35211
 0.21
chr19_4058046_4058288 0.12 CTD-2622I13.3
4580
 0.13
chr14_64887580_64888013 0.12 CTD-2555O16.4
21160
 0.12
chr1_39542017_39542168 0.12 MACF1
 microtubule-actin crosslinking factor 1
 4896
 0.2
chr21_46352814_46353176 0.12 ITGB2
 integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
 1091
 0.32
chr11_10373135_10373286 0.12 AMPD3
 adenosine monophosphate deaminase 3
 33992
 0.13
chr3_46735633_46736482 0.12 ALS2CL
 ALS2 C-terminal like
 866
 0.49
chr8_22435891_22436512 0.12 PDLIM2
 PDZ and LIM domain 2 (mystique)
 53
 0.95
chr9_101504493_101504644 0.12 GABBR2
 gamma-aminobutyric acid (GABA) B receptor, 2
 33089
 0.17
chr21_39699075_39699226 0.12 KCNJ15
 potassium inwardly-rectifying channel, subfamily J, member 15
 30302
 0.23
chr22_45124444_45125024 0.12 PRR5
 proline rich 5 (renal)
 1950
 0.33
chr9_81835383_81835534 0.12 TLE4
 transducin-like enhancer of split 4 (E(sp1) homolog, Drosophila)
 351230
 0.01
chr10_29932554_29932705 0.12 SVIL
 supervillin
 8728
 0.22
chr6_113966832_113966983 0.12 ENSG00000266650
 .
 42790
 0.17
chr1_183066088_183066239 0.12 LAMC1
 laminin, gamma 1 (formerly LAMB2)
 484
 0.84
chr14_52465763_52465914 0.12 C14orf166
 chromosome 14 open reading frame 166
 5394
 0.16
chr12_77772821_77772972 0.12 AC073528.1
177672
 0.03
chr18_417467_417750 0.12 RP11-720L2.2
6808
 0.26
chr9_132949422_132949573 0.12 NCS1
 neuronal calcium sensor 1
 13375
 0.21
chr3_57198236_57199040 0.12 IL17RD
 interleukin 17 receptor D
 765
 0.66
chr19_47250337_47250584 0.12 STRN4
 striatin, calmodulin binding protein 4
 209
 0.57
chr20_48747322_48747473 0.12 TMEM189
 transmembrane protein 189
 272
 0.91
chr2_43310118_43310569 0.11 ENSG00000207087
 .
 8289
 0.3
chr22_18198591_18198742 0.11 ENSG00000264757
 .
 48359
 0.11
chr11_64622528_64623266 0.11 CDC42BPG
 CDC42 binding protein kinase gamma (DMPK-like)
 10856
 0.1
chr11_70053593_70053875 0.11 RP11-805J14.5
238
 0.9
chr16_85169897_85170486 0.11 FAM92B
 family with sequence similarity 92, member B
 24077
 0.18
chrX_109404405_109404556 0.11 ENSG00000208883
 .
 63811
 0.11
chr18_20074465_20074616 0.11 CTAGE1
 cutaneous T-cell lymphoma-associated antigen 1
 76662
 0.11
chr10_33418933_33419614 0.11 ENSG00000263576
 .
 31709
 0.18
chr12_64424546_64424697 0.11 SRGAP1
 SLIT-ROBO Rho GTPase activating protein 1
 48316
 0.13
chr7_107284240_107284391 0.11 SLC26A4
 solute carrier family 26 (anion exchanger), member 4
 16765
 0.14
chr15_72876047_72876198 0.11 ENSG00000207690
 .
 3436
 0.2
chr14_99423824_99424048 0.11 AL162151.4
200817
 0.03
chr10_95195819_95196061 0.11 MYOF
 myoferlin
 46011
 0.14
chr9_117668023_117668209 0.11 TNFSF8
 tumor necrosis factor (ligand) superfamily, member 8
 24581
 0.23
chr12_127726319_127726470 0.11 ENSG00000239776
 .
 75722
 0.12
chr15_70146302_70146453 0.11 ENSG00000215958
 .
 68534
 0.13
chr1_40310608_40311589 0.11 ENSG00000202222
 .
 36252
 0.1
chr17_16380565_16380716 0.11 FAM211A
 family with sequence similarity 211, member A
 14692
 0.15
chr15_63045655_63045939 0.11 TLN2
 talin 2
 4992
 0.22
chr7_17183401_17183552 0.11 AC003075.4
137451
 0.05
chr10_61142512_61142663 0.11 FAM13C
 family with sequence similarity 13, member C
 19648
 0.27
chr7_131752106_131752257 0.11 ENSG00000252849
 .
 151100
 0.04
chr19_2042508_2043083 0.11 MKNK2
 MAP kinase interacting serine/threonine kinase 2
 163
 0.91
chr20_17789544_17789695 0.11 ENSG00000221220
 .
 33608
 0.17
chr18_8231250_8231401 0.11 ENSG00000212067
 .
 4142
 0.29
chr14_93473458_93473609 0.11 ITPK1
 inositol-tetrakisphosphate 1-kinase
 59170
 0.11
chr7_80128841_80128992 0.11 GNAT3
 guanine nucleotide binding protein, alpha transducing 3
 12420
 0.28
chr4_7815652_7815803 0.11 AFAP1
 actin filament associated protein 1
 58082
 0.12
chr1_157987064_157987215 0.11 KIRREL-IT1
 KIRREL intronic transcript 1 (non-protein coding)
 8201
 0.22
chr5_52324302_52324453 0.11 CTD-2175A23.1
38269
 0.14
chr17_16959282_16959681 0.11 MPRIP
 myosin phosphatase Rho interacting protein
 13318
 0.17
chr11_71850699_71850850 0.11 FOLR3
 folate receptor 3 (gamma)
 3880
 0.11
chr14_75994814_75994965 0.11 BATF
 basic leucine zipper transcription factor, ATF-like
 5986
 0.2
chr8_49288664_49288870 0.11 ENSG00000252710
 .
 68177
 0.14
chr14_21714763_21714917 0.11 HNRNPC
 heterogeneous nuclear ribonucleoprotein C (C1/C2)
 15259
 0.16
chr4_47852974_47853125 0.11 CORIN
 corin, serine peptidase
 12926
 0.21
chr14_100771951_100772442 0.11 SLC25A29
 solute carrier family 25 (mitochondrial carnitine/acylcarnitine carrier), member 29
 582
 0.51
chr2_43572005_43572156 0.11 ENSG00000252804
 .
 63366
 0.13

Histogram of CRE-TSS distances for CREs targeted by :

Histogram of

Rank distribution of CRE target scores:

Histogram of target CRE score.

Distribution of target CREs across different genomic regions:

Weighted Piechart of Weighted Piechart of Weighted Piechart of

Network of associatons between targets according to the STRING database.

StringDB image

First level regulatory network of NR5A2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0031946 regulation of glucocorticoid biosynthetic process(GO:0031946)
0.0 0.1 GO:0060666 dichotomous subdivision of terminal units involved in salivary gland branching(GO:0060666)
0.0 0.1 GO:0044413 evasion or tolerance of host defenses by virus(GO:0019049) avoidance of host defenses(GO:0044413) evasion or tolerance of host defenses(GO:0044415) avoidance of defenses of other organism involved in symbiotic interaction(GO:0051832) evasion or tolerance of defenses of other organism involved in symbiotic interaction(GO:0051834)
0.0 0.1 GO:0030644 cellular chloride ion homeostasis(GO:0030644) chloride ion homeostasis(GO:0055064)
0.0 0.1 GO:0060394 negative regulation of pathway-restricted SMAD protein phosphorylation(GO:0060394)
0.0 0.1 GO:0071364 cellular response to epidermal growth factor stimulus(GO:0071364)
0.0 0.1 GO:0060539 diaphragm development(GO:0060539)
0.0 0.1 GO:0019511 peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401) 4-hydroxyproline metabolic process(GO:0019471) peptidyl-proline hydroxylation(GO:0019511)
0.0 0.1 GO:0001955 blood vessel maturation(GO:0001955)
0.0 0.1 GO:0010803 regulation of tumor necrosis factor-mediated signaling pathway(GO:0010803)
0.0 0.1 GO:0034063 stress granule assembly(GO:0034063)
0.0 0.1 GO:0032488 Cdc42 protein signal transduction(GO:0032488)
0.0 0.1 GO:0072007 mesangial cell differentiation(GO:0072007) kidney interstitial fibroblast differentiation(GO:0072071) renal interstitial fibroblast development(GO:0072141) mesangial cell development(GO:0072143) pericyte cell differentiation(GO:1904238)
0.0 0.1 GO:0070141 response to UV-A(GO:0070141)
0.0 0.1 GO:0070777 D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
0.0 0.1 GO:0021508 floor plate formation(GO:0021508)
0.0 0.1 GO:0007132 meiotic metaphase I(GO:0007132)
0.0 0.1 GO:0032656 regulation of interleukin-13 production(GO:0032656)
0.0 0.1 GO:1900116 sequestering of extracellular ligand from receptor(GO:0035581) sequestering of TGFbeta in extracellular matrix(GO:0035583) protein localization to extracellular region(GO:0071692) maintenance of protein location in extracellular region(GO:0071694) extracellular regulation of signal transduction(GO:1900115) extracellular negative regulation of signal transduction(GO:1900116)
0.0 0.1 GO:0034626 fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.0 0.1 GO:0022617 extracellular matrix disassembly(GO:0022617)
0.0 0.2 GO:0002281 macrophage activation involved in immune response(GO:0002281)
0.0 0.1 GO:0032455 nerve growth factor processing(GO:0032455)
0.0 0.0 GO:0072194 positive regulation of smooth muscle cell differentiation(GO:0051152) kidney smooth muscle tissue development(GO:0072194)
0.0 0.1 GO:0071681 response to indole-3-methanol(GO:0071680) cellular response to indole-3-methanol(GO:0071681)
0.0 0.1 GO:0031340 positive regulation of vesicle fusion(GO:0031340)
0.0 0.1 GO:0043589 skin morphogenesis(GO:0043589)
0.0 0.1 GO:0051988 regulation of attachment of spindle microtubules to kinetochore(GO:0051988)
0.0 0.1 GO:0010815 bradykinin catabolic process(GO:0010815)
0.0 0.1 GO:0060662 tube lumen cavitation(GO:0060605) salivary gland cavitation(GO:0060662)
0.0 0.0 GO:0034625 fatty acid elongation, monounsaturated fatty acid(GO:0034625)
0.0 0.0 GO:0071436 sodium ion export(GO:0071436)
0.0 0.0 GO:0072033 renal vesicle formation(GO:0072033)
0.0 0.2 GO:0001542 ovulation from ovarian follicle(GO:0001542)
0.0 0.0 GO:0018076 N-terminal peptidyl-lysine acetylation(GO:0018076)
0.0 0.1 GO:0007016 cytoskeletal anchoring at plasma membrane(GO:0007016)
0.0 0.0 GO:0001778 plasma membrane repair(GO:0001778)
0.0 0.0 GO:0042118 endothelial cell activation(GO:0042118)
0.0 0.0 GO:0090273 regulation of somatostatin secretion(GO:0090273)
0.0 0.0 GO:0007221 positive regulation of transcription of Notch receptor target(GO:0007221)
0.0 0.0 GO:0045112 integrin biosynthetic process(GO:0045112)
0.0 0.1 GO:0055094 response to lipoprotein particle(GO:0055094)
0.0 0.1 GO:0046952 ketone body catabolic process(GO:0046952)
0.0 0.1 GO:0006600 creatine metabolic process(GO:0006600)
0.0 0.1 GO:0070670 response to interleukin-4(GO:0070670)
0.0 0.1 GO:0031581 hemidesmosome assembly(GO:0031581)
0.0 0.1 GO:0035414 negative regulation of catenin import into nucleus(GO:0035414)
0.0 0.1 GO:0007386 compartment pattern specification(GO:0007386)
0.0 0.0 GO:0048742 regulation of skeletal muscle fiber development(GO:0048742)
0.0 0.0 GO:0071803 regulation of podosome assembly(GO:0071801) positive regulation of podosome assembly(GO:0071803)
0.0 0.0 GO:0002248 connective tissue replacement involved in inflammatory response wound healing(GO:0002248) connective tissue replacement(GO:0097709)
0.0 0.1 GO:0046541 saliva secretion(GO:0046541)
0.0 0.0 GO:0071502 cellular response to temperature stimulus(GO:0071502)
0.0 0.0 GO:0017121 phospholipid scrambling(GO:0017121)
0.0 0.0 GO:0051176 positive regulation of sulfur metabolic process(GO:0051176)
0.0 0.0 GO:0014045 establishment of endothelial blood-brain barrier(GO:0014045) central nervous system vasculogenesis(GO:0022009)
0.0 0.0 GO:0060287 epithelial cilium movement(GO:0003351) epithelial cilium movement involved in determination of left/right asymmetry(GO:0060287)
0.0 0.0 GO:0036037 CD8-positive, alpha-beta T cell activation(GO:0036037) CD8-positive, alpha-beta T cell differentiation(GO:0043374)
0.0 0.1 GO:0005984 disaccharide metabolic process(GO:0005984)
0.0 0.0 GO:0060083 smooth muscle contraction involved in micturition(GO:0060083)
0.0 0.0 GO:0016103 diterpenoid catabolic process(GO:0016103) terpenoid catabolic process(GO:0016115) retinoic acid catabolic process(GO:0034653)
0.0 0.0 GO:0051124 synaptic growth at neuromuscular junction(GO:0051124)
0.0 0.0 GO:0010766 negative regulation of sodium ion transport(GO:0010766)
0.0 0.1 GO:0006108 malate metabolic process(GO:0006108)
0.0 0.0 GO:0050916 sensory perception of sweet taste(GO:0050916)
0.0 0.0 GO:0033145 positive regulation of intracellular steroid hormone receptor signaling pathway(GO:0033145)
0.0 0.0 GO:0021932 hindbrain radial glia guided cell migration(GO:0021932)
0.0 0.0 GO:0048808 male genitalia morphogenesis(GO:0048808) male anatomical structure morphogenesis(GO:0090598)
0.0 0.0 GO:0042160 plasma lipoprotein particle oxidation(GO:0034441) regulation of lipoprotein oxidation(GO:0034442) negative regulation of lipoprotein oxidation(GO:0034443) regulation of plasma lipoprotein particle oxidation(GO:0034444) negative regulation of plasma lipoprotein particle oxidation(GO:0034445) lipoprotein modification(GO:0042160) lipoprotein oxidation(GO:0042161)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0043259 laminin-10 complex(GO:0043259)
0.0 0.1 GO:0030934 anchoring collagen complex(GO:0030934)
0.0 0.1 GO:0071437 invadopodium(GO:0071437)
0.0 0.1 GO:0098647 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.0 0.1 GO:0005899 insulin receptor complex(GO:0005899)
0.0 0.1 GO:0030056 hemidesmosome(GO:0030056)
0.0 0.1 GO:0016342 catenin complex(GO:0016342)
0.0 0.0 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.0 0.1 GO:0005766 primary lysosome(GO:0005766) azurophil granule(GO:0042582)
0.0 0.0 GO:0071664 catenin-TCF7L2 complex(GO:0071664)
0.0 0.1 GO:0043256 laminin complex(GO:0043256)
0.0 0.0 GO:0034673 inhibin-betaglycan-ActRII complex(GO:0034673)
0.0 0.0 GO:0005826 actomyosin contractile ring(GO:0005826)
0.0 0.0 GO:0030312 external encapsulating structure(GO:0030312)
0.0 0.1 GO:0031332 RISC complex(GO:0016442) RNAi effector complex(GO:0031332)
0.0 0.0 GO:0071942 XPC complex(GO:0071942)
0.0 0.0 GO:0044217 host(GO:0018995) host cell part(GO:0033643) host intracellular part(GO:0033646) intracellular region of host(GO:0043656) host cell(GO:0043657) other organism(GO:0044215) other organism cell(GO:0044216) other organism part(GO:0044217)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 GO:0004111 creatine kinase activity(GO:0004111)
0.0 0.1 GO:0005010 insulin-like growth factor-activated receptor activity(GO:0005010)
0.0 0.1 GO:0042808 obsolete neuronal Cdc2-like kinase binding(GO:0042808)
0.0 0.1 GO:0032794 GTPase activating protein binding(GO:0032794)
0.0 0.1 GO:0050501 hyaluronan synthase activity(GO:0050501)
0.0 0.2 GO:0017154 semaphorin receptor activity(GO:0017154)
0.0 0.2 GO:0030332 cyclin binding(GO:0030332)
0.0 0.1 GO:0070653 high-density lipoprotein particle receptor binding(GO:0070653)
0.0 0.1 GO:0004470 malic enzyme activity(GO:0004470)
0.0 0.1 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.0 0.1 GO:0004656 procollagen-proline 4-dioxygenase activity(GO:0004656) peptidyl-proline 4-dioxygenase activity(GO:0031545)
0.0 0.2 GO:0001085 RNA polymerase II transcription factor binding(GO:0001085)
0.0 0.1 GO:0005006 epidermal growth factor-activated receptor activity(GO:0005006)
0.0 0.1 GO:0033829 O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.0 0.1 GO:0002162 dystroglycan binding(GO:0002162)
0.0 0.1 GO:0050321 tau-protein kinase activity(GO:0050321)
0.0 0.1 GO:0004083 bisphosphoglycerate mutase activity(GO:0004082) bisphosphoglycerate 2-phosphatase activity(GO:0004083) phosphoglycerate mutase activity(GO:0004619)
0.0 0.1 GO:0009922 fatty acid elongase activity(GO:0009922)
0.0 0.1 GO:0043495 protein anchor(GO:0043495)
0.0 0.0 GO:0045545 syndecan binding(GO:0045545)
0.0 0.1 GO:0009374 biotin binding(GO:0009374)
0.0 0.2 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.0 0.1 GO:0070087 chromo shadow domain binding(GO:0070087)
0.0 0.1 GO:0004157 dihydropyrimidinase activity(GO:0004157)
0.0 0.1 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.0 0.0 GO:0032558 purine deoxyribonucleotide binding(GO:0032554) adenyl deoxyribonucleotide binding(GO:0032558)
0.0 0.2 GO:0051721 protein phosphatase 2A binding(GO:0051721)
0.0 0.1 GO:0030172 troponin C binding(GO:0030172)
0.0 0.1 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
0.0 0.1 GO:0035035 histone acetyltransferase binding(GO:0035035)
0.0 0.0 GO:0005025 transforming growth factor beta receptor activity, type I(GO:0005025)
0.0 0.0 GO:0030375 thyroid hormone receptor coactivator activity(GO:0030375)
0.0 0.0 GO:0017128 phospholipid scramblase activity(GO:0017128)
0.0 0.3 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.0 0.1 GO:0005314 high-affinity glutamate transmembrane transporter activity(GO:0005314)
0.0 0.0 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity(GO:0004694)
0.0 0.0 GO:0034187 obsolete apolipoprotein E binding(GO:0034187)
0.0 0.2 GO:0005520 insulin-like growth factor binding(GO:0005520)
0.0 0.1 GO:0008429 phosphatidylethanolamine binding(GO:0008429)
0.0 0.0 GO:0003829 beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity(GO:0003829)
0.0 0.0 GO:0005432 calcium:sodium antiporter activity(GO:0005432)
0.0 0.0 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.0 0.0 GO:0045159 myosin II binding(GO:0045159)
0.0 0.1 GO:0030020 extracellular matrix structural constituent conferring tensile strength(GO:0030020)
0.0 0.0 GO:0000309 nicotinamide-nucleotide adenylyltransferase activity(GO:0000309) nicotinate-nucleotide adenylyltransferase activity(GO:0004515)
0.0 0.0 GO:0003896 DNA primase activity(GO:0003896)
0.0 0.0 GO:0008607 phosphorylase kinase regulator activity(GO:0008607)
0.0 0.1 GO:0016641 oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor(GO:0016641)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.0 PID EPHRINB REV PATHWAY Ephrin B reverse signaling
0.0 0.2 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.0 0.1 PID TXA2PATHWAY Thromboxane A2 receptor signaling
0.0 0.1 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.0 0.1 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.0 0.3 NABA COLLAGENS Genes encoding collagen proteins
0.0 0.6 PID INTEGRIN1 PATHWAY Beta1 integrin cell surface interactions
0.0 0.0 PID EPHA2 FWD PATHWAY EPHA2 forward signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 REACTOME CRMPS IN SEMA3A SIGNALING Genes involved in CRMPs in Sema3A signaling
0.0 0.1 REACTOME PROSTANOID LIGAND RECEPTORS Genes involved in Prostanoid ligand receptors