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ENCODE: H3K4me1 ChIP-Seq of primary human cells

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CREMA is a free online tool that recognizes most important transcription factors that change the chromatin state across different samples.

Results for NR6A1

Z-value: 0.87

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Transcription factors associated with NR6A1

Gene Symbol	Gene ID	Gene Info
NR6A1 Ensembl NCBI GeneCards UniProt	ENSG00000148200.12	NR6A1

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE	Gene	Distance	Association probability	Pearson corr. coef.	P-value	Plot
NR6A1	chr9_127536416_127536567	2902	0.179622	0.88	1.9e-03	Click!
NR6A1	chr9_127316512_127316663	41500	0.123718	-0.77	1.4e-02	Click!
NR6A1	chr9_127336792_127336943	21220	0.164299	-0.75	1.9e-02	Click!
NR6A1	chr9_127314112_127314350	43856	0.118728	-0.68	4.3e-02	Click!
NR6A1	chr9_127314557_127314840	43389	0.119713	-0.68	4.4e-02	Click!

Activity of the NR6A1 motif across conditions

Conditions sorted by the z-value of the NR6A1 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE)	Target Score	Top associated gene	Gene Info	Distance of CRE to TSS	CRE/Gene association probability
chr14_72947953_72948226	0.35	RGS6	regulator of G-protein signaling 6	21712	0.28
chrX_13108038_13108679	0.33	FAM9C	family with sequence similarity 9, member C	45557	0.18
chr9_123652141_123652292	0.32	PHF19	PHD finger protein 19	12610	0.18
chr17_72751609_72751889	0.31	SLC9A3R1	solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 1	6393	0.1
chr8_82019930_82020142	0.29	PAG1	phosphoprotein associated with glycosphingolipid microdomains 1	4267	0.34
chr1_8488032_8488525	0.29	RP5-1115A15.1		2580	0.27
chr15_40596685_40596954	0.29	PLCB2	phospholipase C, beta 2	3207	0.11
chr21_45509890_45510158	0.28	PWP2	PWP2 periodic tryptophan protein homolog (yeast)	17147	0.16
chr10_129860224_129860381	0.27	PTPRE	protein tyrosine phosphatase, receptor type, E	14468	0.26
chr1_197360685_197361146	0.27	CRB1	crumbs homolog 1 (Drosophila)	22044	0.23
chr19_12775707_12775982	0.27	MAN2B1	mannosidase, alpha, class 2B, member 1	1704	0.14
chr1_32825530_32825738	0.25	FAM229A	family with sequence similarity 229, member A	1791	0.22
chr7_148325963_148326351	0.25	C7orf33	chromosome 7 open reading frame 33	38500	0.16
chr15_86128935_86129221	0.24	RP11-815J21.2		5669	0.19
chr9_22075219_22075414	0.24	CDKN2B-AS1	CDKN2B antisense RNA 1	28566	0.18
chr11_67173722_67173982	0.24	TBC1D10C	TBC1 domain family, member 10C	2192	0.12
chr2_143898363_143898928	0.24	ARHGAP15	Rho GTPase activating protein 15	11762	0.25
chr8_134528898_134529424	0.23	ST3GAL1	ST3 beta-galactoside alpha-2,3-sialyltransferase 1	17535	0.28
chr9_92151633_92152777	0.23	SEMA4D	sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D	39160	0.16
chr1_206755327_206755741	0.23	RASSF5	Ras association (RalGDS/AF-6) domain family member 5	25041	0.13
chr1_54946013_54946309	0.23	ENSG00000265404	.	24180	0.16
chr3_16556525_16556706	0.22	RFTN1	raftlin, lipid raft linker 1	1082	0.63
chr16_17545376_17545755	0.22	XYLT1	xylosyltransferase I	19173	0.3
chr1_206747367_206748212	0.22	RASSF5	Ras association (RalGDS/AF-6) domain family member 5	17296	0.15
chr17_14233383_14233629	0.21	HS3ST3B1	heparan sulfate (glucosamine) 3-O-sulfotransferase 3B1	29106	0.23
chr3_46411481_46411895	0.21	CCR5	chemokine (C-C motif) receptor 5 (gene/pseudogene)	55	0.97
chr18_60806585_60806736	0.21	RP11-299P2.1		11893	0.25
chr6_90981736_90981993	0.21	BACH2	BTB and CNC homology 1, basic leucine zipper transcription factor 2	24597	0.22
chr2_136895658_136895809	0.21	CXCR4	chemokine (C-X-C motif) receptor 4	19998	0.26
chr9_117701644_117701992	0.21	TNFSF8	tumor necrosis factor (ligand) superfamily, member 8	9121	0.28
chrX_13102950_13103119	0.21	FAM9C	family with sequence similarity 9, member C	40233	0.19
chr1_111421634_111421896	0.21	CD53	CD53 molecule	5989	0.21
chr21_32736198_32736388	0.21	TIAM1	T-cell lymphoma invasion and metastasis 1	19699	0.27
chr1_209925627_209925957	0.21	TRAF3IP3	TRAF3 interacting protein 3	3585	0.18
chr4_143622207_143622596	0.21	INPP4B	inositol polyphosphate-4-phosphatase, type II, 105kDa	140579	0.05
chr5_118645803_118646226	0.20	ENSG00000243333	.	3688	0.25
chr9_134146913_134147198	0.20	FAM78A	family with sequence similarity 78, member A	1145	0.48
chr2_196423126_196423304	0.20	SLC39A10	solute carrier family 39 (zinc transporter), member 10	17486	0.24
chrX_20458891_20459042	0.20	ENSG00000252978	.	11260	0.3
chrX_40138916_40139203	0.20	ENSG00000238920	.	5290	0.32
chr3_187696963_187697463	0.20	LPP	LIM domain containing preferred translocation partner in lipoma	173859	0.03
chr15_60836979_60837190	0.20	CTD-2501E16.2		14912	0.19
chr8_71275992_71276158	0.20	ENSG00000207036	.	6493	0.25
chrX_134518932_134519216	0.20	ZNF449	zinc finger protein 449	40353	0.13
chr18_43620867_43621135	0.20	PSTPIP2	proline-serine-threonine phosphatase interacting protein 2	31222	0.13
chr10_22899051_22899369	0.20	PIP4K2A	phosphatidylinositol-5-phosphate 4-kinase, type II, alpha	18568	0.27
chr15_85141859_85142174	0.20	ZSCAN2	zinc finger and SCAN domain containing 2	2201	0.19
chrX_135848042_135848429	0.20	ARHGEF6	Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6	1267	0.45
chr9_130623880_130624317	0.19	ENG	endoglin	7063	0.08
chr17_27228319_27228798	0.19	DHRS13	dehydrogenase/reductase (SDR family) member 13	1425	0.19
chr18_60880832_60881273	0.19	ENSG00000238988	.	19154	0.21
chr17_33543338_33543516	0.19	RP11-799D4.4		21573	0.11
chr11_67173408_67173659	0.19	TBC1D10C	TBC1 domain family, member 10C	1873	0.13
chr11_128608264_128608441	0.19	FLI1	Fli-1 proto-oncogene, ETS transcription factor	26333	0.17
chr10_11224652_11224918	0.19	RP3-323N1.2		11446	0.22
chr16_27240742_27240893	0.19	NSMCE1	non-SMC element 1 homolog (S. cerevisiae)	3582	0.21
chr10_7233978_7234351	0.19	SFMBT2	Scm-like with four mbt domains 2	216543	0.02
chr17_3863445_3863626	0.19	ATP2A3	ATPase, Ca++ transporting, ubiquitous	4050	0.22
chr4_143617070_143617312	0.19	INPP4B	inositol polyphosphate-4-phosphatase, type II, 105kDa	135369	0.06
chr1_11789201_11789352	0.19	AGTRAP	angiotensin II receptor-associated protein	6865	0.13
chr2_240219157_240219354	0.19	ENSG00000265215	.	7902	0.19
chr1_232715110_232715328	0.19	SIPA1L2	signal-induced proliferation-associated 1 like 2	17915	0.28
chr20_31554218_31554478	0.19	EFCAB8	EF-hand calcium binding domain 8	6697	0.17
chr1_206945881_206946032	0.19	IL10	interleukin 10	117	0.96
chr1_159037154_159037495	0.19	ENSG00000265589	.	8285	0.18
chr16_85342323_85342695	0.19	ENSG00000266307	.	2578	0.35
chr1_169575119_169575302	0.19	SELP	selectin P (granule membrane protein 140kDa, antigen CD62)	13247	0.2
chrX_42259008_42259366	0.19	ENSG00000206896	.	225549	0.02
chr10_11203289_11203522	0.19	CELF2	CUGBP, Elav-like family member 2	3588	0.26
chr2_28570986_28571140	0.19	AC093690.1		37737	0.13
chr1_167602468_167602965	0.18	RP3-455J7.4		2805	0.25
chr7_50257067_50257311	0.18	AC020743.2		74770	0.1
chr4_6920362_6920560	0.18	TBC1D14	TBC1 domain family, member 14	8486	0.18
chr14_91855068_91855898	0.18	CCDC88C	coiled-coil domain containing 88C	28207	0.19
chr20_47782632_47782783	0.18	STAU1	staufen double-stranded RNA binding protein 1	8093	0.21
chr5_130731828_130731979	0.18	CDC42SE2	CDC42 small effector 2	10604	0.3
chr6_52200307_52200580	0.18	PAQR8	progestin and adipoQ receptor family member VIII	25776	0.19
chr1_12231932_12232095	0.18	TNFRSF1B	tumor necrosis factor receptor superfamily, member 1B	4953	0.18
chr16_28622056_28622448	0.18	SULT1A1	sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1	899	0.46
chr3_60090466_60090753	0.18	NPCDR1	nasopharyngeal carcinoma, down-regulated 1	133026	0.06
chr6_41170433_41170835	0.18	TREML2	triggering receptor expressed on myeloid cells-like 2	1702	0.26
chr9_130473685_130473878	0.18	C9orf117	chromosome 9 open reading frame 117	388	0.73
chr17_75925692_75925843	0.18	ENSG00000238898	.	9587	0.22
chr12_53602242_53602592	0.18	ITGB7	integrin, beta 7	1326	0.29
chr12_64992774_64993476	0.18	RP11-338E21.1		10114	0.13
chr11_128162482_128162771	0.18	ETS1	v-ets avian erythroblastosis virus E26 oncogene homolog 1	212663	0.02
chr13_41176876_41177104	0.18	FOXO1	forkhead box O1	63744	0.11
chr12_92756626_92757039	0.18	RP11-693J15.4		58475	0.12
chr10_26745731_26745940	0.18	APBB1IP	amyloid beta (A4) precursor protein-binding, family B, member 1 interacting protein	18481	0.24
chr3_56823289_56823680	0.18	ARHGEF3	Rho guanine nucleotide exchange factor (GEF) 3	12493	0.28
chr5_131744783_131745111	0.18	C5orf56	chromosome 5 open reading frame 56	1381	0.32
chr21_44819666_44819955	0.18	SIK1	salt-inducible kinase 1	27198	0.24
chr10_6585736_6586147	0.18	PRKCQ	protein kinase C, theta	36260	0.23
chr6_41975005_41975289	0.18	ENSG00000206875	.	11105	0.16
chr6_14373007_14373158	0.18	ENSG00000238987	.	216389	0.02
chr13_95836619_95836770	0.18	ENSG00000238463	.	25904	0.23
chr1_229170121_229170313	0.18	RP5-1061H20.5		193092	0.02
chr1_65330970_65331121	0.18	RAVER2	ribonucleoprotein, PTB-binding 2	87298	0.09
chr2_234177577_234177728	0.18	ENSG00000252010	.	6721	0.15
chr5_75770152_75770552	0.18	IQGAP2	IQ motif containing GTPase activating protein 2	70103	0.12
chr6_53109375_53109667	0.18	ENSG00000206908	.	25462	0.15
chr19_7411370_7411784	0.18	CTB-133G6.1		2271	0.26
chr1_112054315_112054681	0.18	ADORA3	adenosine A3 receptor	8116	0.13
chr2_60780651_60780821	0.18	BCL11A	B-cell CLL/lymphoma 11A (zinc finger protein)	34	0.98
chr10_6583895_6584058	0.18	PRKCQ	protein kinase C, theta	38225	0.22
chr10_11193217_11193852	0.18	CELF2	CUGBP, Elav-like family member 2	13459	0.2
chr14_24807724_24807962	0.18	RIPK3	receptor-interacting serine-threonine kinase 3	1235	0.19
chr21_36401379_36401530	0.18	RUNX1	runt-related transcription factor 1	20008	0.29
chr8_103121247_103121419	0.18	NCALD	neurocalcin delta	14845	0.21
chr6_52241496_52241889	0.18	PAQR8	progestin and adipoQ receptor family member VIII	14448	0.22
chrX_70318458_70318852	0.17	FOXO4	forkhead box O4	2276	0.17
chr5_76152388_76152629	0.17	S100Z	S100 calcium binding protein Z	6584	0.18
chr17_38760477_38760676	0.17	SMARCE1	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 1	27966	0.12
chr6_24962302_24962654	0.17	FAM65B	family with sequence similarity 65, member B	26290	0.19
chr8_145085888_145086183	0.17	SPATC1	spermatogenesis and centriole associated 1	547	0.47
chr13_110222272_110222771	0.17	LINC00676	long intergenic non-protein coding RNA 676	158108	0.04
chr1_27165220_27165588	0.17	ZDHHC18	zinc finger, DHHC-type containing 18	6893	0.12
chr3_52303914_52304065	0.17	ENSG00000199150	.	1610	0.2
chr8_131025939_131026245	0.17	FAM49B	family with sequence similarity 49, member B	2559	0.24
chr19_13993263_13993689	0.17	NANOS3	nanos homolog 3 (Drosophila)	5413	0.09
chr4_129783038_129783517	0.17	JADE1	jade family PHD finger 1	30689	0.24
chr1_100830416_100830661	0.17	CDC14A	cell division cycle 14A	12033	0.18
chr3_187676645_187676932	0.17	LPP	LIM domain containing preferred translocation partner in lipoma	194284	0.03
chr4_99367280_99367535	0.17	RP11-724M22.1		50108	0.16
chr17_74148395_74148576	0.17	RNF157-AS1	RNF157 antisense RNA 1	1308	0.31
chr3_16880178_16880359	0.17	PLCL2	phospholipase C-like 2	46184	0.18
chr14_104855874_104856139	0.17	ENSG00000222761	.	11379	0.26
chr2_109833807_109834002	0.17	ENSG00000264934	.	75860	0.1
chr20_5623012_5623187	0.17	GPCPD1	glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae)	31427	0.21
chr7_69068510_69068661	0.17	AUTS2	autism susceptibility candidate 2	3988	0.32
chr19_39107432_39107629	0.17	MAP4K1	mitogen-activated protein kinase kinase kinase kinase 1	1034	0.37
chr11_110709081_110709232	0.17	ARHGAP20	Rho GTPase activating protein 20	125244	0.06
chr3_177662901_177663156	0.17	ENSG00000199858	.	62539	0.16
chr14_61909696_61909971	0.17	PRKCH	protein kinase C, eta	557	0.83
chr8_19554391_19555213	0.17	CSGALNACT1	chondroitin sulfate N-acetylgalactosaminyltransferase 1	14530	0.29
chr4_4420478_4420740	0.17	NSG1	Homo sapiens neuron specific gene family member 1 (NSG1), transcript variant 3, mRNA.	31777	0.16
chr19_16229174_16229347	0.17	RAB8A	RAB8A, member RAS oncogene family	6553	0.14
chr9_92056751_92057221	0.17	SEMA4D	sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D	5588	0.27
chr1_160579528_160579679	0.17	CD84	CD84 molecule	30297	0.12
chr10_11237002_11237580	0.17	RP3-323N1.2		23952	0.2
chr2_191934456_191934744	0.17	ENSG00000231858	.	48348	0.11
chr6_15264518_15264669	0.17	JARID2	jumonji, AT rich interactive domain 2	15450	0.18
chr18_2960888_2961200	0.17	RP11-737O24.1		5972	0.16
chr5_55387236_55387387	0.17	ANKRD55	ankyrin repeat domain 55	25467	0.16
chr5_67674468_67674625	0.17	PIK3R1	phosphoinositide-3-kinase, regulatory subunit 1 (alpha)	86150	0.1
chr3_16942822_16942973	0.17	PLCL2	phospholipase C-like 2	16445	0.23
chr4_90208438_90208788	0.17	GPRIN3	GPRIN family member 3	20548	0.27
chr10_6603625_6603862	0.17	PRKCQ	protein kinase C, theta	18458	0.29
chr1_69963453_69963604	0.17	LRRC7	leucine rich repeat containing 7	70553	0.14
chr2_101946285_101946451	0.17	ENSG00000264857	.	20456	0.16
chr8_129664945_129665222	0.17	ENSG00000221351	.	166957	0.04
chr1_108741850_108742080	0.16	RP11-483I13.5		583	0.61
chr10_17469337_17469935	0.16	ST8SIA6-AS1	ST8SIA6 antisense RNA 1	19610	0.17
chr9_20228261_20228412	0.16	ENSG00000221744	.	66666	0.13
chr4_109275787_109275938	0.16	ENSG00000232021	.	178418	0.03
chr7_50301548_50301699	0.16	IKZF1	IKAROS family zinc finger 1 (Ikaros)	42701	0.19
chr14_90147407_90147667	0.16	ENSG00000252655	.	30290	0.14
chr12_57456902_57457053	0.16	MYO1A	myosin IA	12018	0.1
chr1_208045857_208046008	0.16	CD34	CD34 molecule	17905	0.25
chr16_21658961_21659187	0.16	IGSF6	immunoglobulin superfamily, member 6	4853	0.13
chr1_17759092_17759354	0.16	RCC2	regulator of chromosome condensation 2	5834	0.17
chr16_31488982_31489389	0.16	TGFB1I1	transforming growth factor beta 1 induced transcript 1	4438	0.1
chr12_781338_781694	0.16	NINJ2	ninjurin 2	8571	0.19
chr11_306863_307074	0.16	IFITM2	interferon induced transmembrane protein 2	663	0.42
chr9_80622373_80622560	0.16	GNAQ	guanine nucleotide binding protein (G protein), q polypeptide	23054	0.27
chr12_76934517_76934736	0.16	OSBPL8	oxysterol binding protein-like 8	18658	0.28
chr7_150374566_150375043	0.16	GIMAP2	GTPase, IMAP family member 2	7984	0.18
chr14_93124277_93124612	0.16	RIN3	Ras and Rab interactor 3	5598	0.29
chr16_3126091_3126264	0.16	ENSG00000252561	.	6653	0.06
chr12_12626467_12626673	0.16	DUSP16	dual specificity phosphatase 16	47489	0.15
chr5_175956521_175957004	0.16	RNF44	ring finger protein 44	884	0.47
chr5_75685944_75686439	0.16	IQGAP2	IQ motif containing GTPase activating protein 2	12883	0.27
chr19_6654326_6654734	0.16	TNFSF14	tumor necrosis factor (ligand) superfamily, member 14	15598	0.13
chr2_135425836_135426057	0.16	TMEM163	transmembrane protein 163	50624	0.17
chr15_93579557_93579854	0.16	CHD2	chromodomain helicase DNA binding protein 2	27609	0.2
chr2_106370179_106370624	0.16	NCK2	NCK adaptor protein 2	8213	0.3
chr19_7458115_7458266	0.16	CTB-133G6.2		1735	0.24
chr12_68848636_68848957	0.16	MDM1	Mdm1 nuclear protein homolog (mouse)	122635	0.05
chr2_220112096_220112414	0.16	STK16	serine/threonine kinase 16	1637	0.15
chr14_51711081_51711357	0.16	ENSG00000201376	.	411	0.84
chr15_41735495_41735646	0.16	ENSG00000200407	.	5472	0.16
chr7_26410221_26410372	0.16	AC004540.4		5596	0.24
chr7_7199791_7199942	0.16	C1GALT1	core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase, 1	3301	0.25
chrX_41969111_41969315	0.16	ENSG00000212560	.	29570	0.22
chr12_111888335_111888486	0.16	ATXN2	ataxin 2	5506	0.19
chr1_207244347_207244498	0.16	PFKFB2	6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2	6073	0.14
chr10_22422484_22422726	0.16	EBLN1	endogenous Bornavirus-like nucleoprotein 1	76345	0.1
chr19_56143009_56143160	0.16	ZNF580	zinc finger protein 580	3298	0.09
chr3_71277170_71277635	0.16	FOXP1	forkhead box P1	16914	0.27
chr7_72939321_72939472	0.16	BAZ1B	bromodomain adjacent to zinc finger domain, 1B	2788	0.21
chr9_117136205_117136760	0.16	AKNA	AT-hook transcription factor	2762	0.28
chr19_54899589_54899740	0.16	LAIR1	leukocyte-associated immunoglobulin-like receptor 1	17499	0.09
chr20_56039749_56039992	0.16	CTCFL	CCCTC-binding factor (zinc finger protein)-like	59443	0.1
chr6_36139598_36139749	0.16	BRPF3	bromodomain and PHD finger containing, 3	24848	0.13
chr7_148418097_148418248	0.16	ENSG00000264918	.	9848	0.18
chr1_167612000_167612291	0.16	RP3-455J7.4		12234	0.19
chrX_16612049_16612225	0.16	ENSG00000265144	.	33071	0.16
chr3_105904284_105904435	0.16	CBLB	Cbl proto-oncogene B, E3 ubiquitin protein ligase	315963	0.01
chr16_23868832_23868983	0.16	PRKCB	protein kinase C, beta	20363	0.23
chr11_73691666_73692195	0.16	UCP2	uncoupling protein 2 (mitochondrial, proton carrier)	53	0.97

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of NR6A1

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.5	GO:0030854	positive regulation of granulocyte differentiation(GO:0030854)
0.1	0.3	GO:0002874	regulation of chronic inflammatory response to antigenic stimulus(GO:0002874)
0.1	0.4	GO:0050857	positive regulation of antigen receptor-mediated signaling pathway(GO:0050857)
0.1	0.3	GO:0045589	regulation of regulatory T cell differentiation(GO:0045589)
0.1	0.3	GO:0046642	negative regulation of alpha-beta T cell proliferation(GO:0046642)
0.1	0.1	GO:0060557	positive regulation of vitamin metabolic process(GO:0046136) positive regulation of vitamin D biosynthetic process(GO:0060557) positive regulation of calcidiol 1-monooxygenase activity(GO:0060559)
0.1	0.2	GO:0032237	activation of store-operated calcium channel activity(GO:0032237) regulation of store-operated calcium channel activity(GO:1901339) positive regulation of store-operated calcium channel activity(GO:1901341)
0.1	0.2	GO:0019276	UDP-N-acetylgalactosamine metabolic process(GO:0019276)
0.1	0.2	GO:0042996	regulation of Golgi to plasma membrane protein transport(GO:0042996)
0.1	0.2	GO:0035405	histone-threonine phosphorylation(GO:0035405)
0.1	0.4	GO:0007172	signal complex assembly(GO:0007172)
0.1	0.1	GO:0002666	T cell tolerance induction(GO:0002517) regulation of T cell tolerance induction(GO:0002664) positive regulation of T cell tolerance induction(GO:0002666)
0.0	0.1	GO:0045348	positive regulation of MHC class II biosynthetic process(GO:0045348)
0.0	0.1	GO:0002925	positive regulation of humoral immune response mediated by circulating immunoglobulin(GO:0002925)
0.0	0.6	GO:0045086	positive regulation of interleukin-2 biosynthetic process(GO:0045086)
0.0	0.1	GO:0048742	regulation of skeletal muscle fiber development(GO:0048742)
0.0	0.1	GO:0001766	membrane raft polarization(GO:0001766) membrane raft distribution(GO:0031580)
0.0	0.6	GO:0006607	NLS-bearing protein import into nucleus(GO:0006607)
0.0	0.1	GO:0002323	natural killer cell activation involved in immune response(GO:0002323) natural killer cell degranulation(GO:0043320)
0.0	0.1	GO:0060523	prostate epithelial cord elongation(GO:0060523)
0.0	0.1	GO:0010572	positive regulation of platelet activation(GO:0010572)
0.0	0.1	GO:0032713	negative regulation of interleukin-4 production(GO:0032713)
0.0	0.2	GO:0031062	positive regulation of histone methylation(GO:0031062)
0.0	0.1	GO:0002282	microglial cell activation involved in immune response(GO:0002282)
0.0	0.2	GO:0033152	immunoglobulin V(D)J recombination(GO:0033152)
0.0	0.3	GO:0006198	cAMP catabolic process(GO:0006198)
0.0	0.1	GO:0048304	positive regulation of isotype switching to IgG isotypes(GO:0048304)
0.0	0.1	GO:0010957	negative regulation of calcidiol 1-monooxygenase activity(GO:0010956) negative regulation of vitamin D biosynthetic process(GO:0010957) negative regulation of vitamin metabolic process(GO:0046137)
0.0	0.3	GO:0030206	chondroitin sulfate biosynthetic process(GO:0030206)
0.0	0.4	GO:0019059	obsolete initiation of viral infection(GO:0019059)
0.0	0.1	GO:0045722	positive regulation of gluconeogenesis(GO:0045722)
0.0	0.0	GO:0033622	integrin activation(GO:0033622)
0.0	0.1	GO:0015917	aminophospholipid transport(GO:0015917)
0.0	0.1	GO:0002313	mature B cell differentiation involved in immune response(GO:0002313)
0.0	0.1	GO:0071072	negative regulation of phospholipid biosynthetic process(GO:0071072)
0.0	0.1	GO:0090116	DNA methylation on cytosine(GO:0032776) C-5 methylation of cytosine(GO:0090116)
0.0	0.4	GO:0000303	response to superoxide(GO:0000303)
0.0	0.1	GO:0006772	thiamine metabolic process(GO:0006772)
0.0	0.1	GO:0043653	mitochondrial fragmentation involved in apoptotic process(GO:0043653)
0.0	0.2	GO:0000185	activation of MAPKKK activity(GO:0000185)
0.0	0.1	GO:0045349	interferon-alpha biosynthetic process(GO:0045349) regulation of interferon-alpha biosynthetic process(GO:0045354) positive regulation of interferon-alpha biosynthetic process(GO:0045356)
0.0	0.1	GO:0030223	neutrophil differentiation(GO:0030223)
0.0	0.0	GO:0045423	regulation of granulocyte macrophage colony-stimulating factor biosynthetic process(GO:0045423)
0.0	0.1	GO:0045056	transcytosis(GO:0045056)
0.0	0.0	GO:0002523	leukocyte migration involved in inflammatory response(GO:0002523)
0.0	0.1	GO:0006678	glucosylceramide metabolic process(GO:0006678)
0.0	0.4	GO:0050853	B cell receptor signaling pathway(GO:0050853)
0.0	0.1	GO:0001672	regulation of chromatin assembly or disassembly(GO:0001672)
0.0	0.1	GO:0003100	regulation of systemic arterial blood pressure by endothelin(GO:0003100)
0.0	0.1	GO:0045657	positive regulation of monocyte differentiation(GO:0045657)
0.0	0.5	GO:0046834	lipid phosphorylation(GO:0046834)
0.0	0.1	GO:0070682	proteasome regulatory particle assembly(GO:0070682)
0.0	0.1	GO:0035455	response to interferon-alpha(GO:0035455)
0.0	0.0	GO:0060397	JAK-STAT cascade involved in growth hormone signaling pathway(GO:0060397)
0.0	0.0	GO:0071801	regulation of podosome assembly(GO:0071801) positive regulation of podosome assembly(GO:0071803)
0.0	0.2	GO:0002714	positive regulation of B cell mediated immunity(GO:0002714) positive regulation of immunoglobulin mediated immune response(GO:0002891)
0.0	0.1	GO:0042989	sequestering of actin monomers(GO:0042989)
0.0	0.1	GO:0003323	type B pancreatic cell development(GO:0003323)
0.0	0.0	GO:0002448	mast cell mediated immunity(GO:0002448)
0.0	0.1	GO:0006975	DNA damage induced protein phosphorylation(GO:0006975)
0.0	0.0	GO:0002887	negative regulation of myeloid leukocyte mediated immunity(GO:0002887) negative regulation of leukocyte degranulation(GO:0043301)
0.0	0.1	GO:0046968	peptide antigen transport(GO:0046968)
0.0	0.0	GO:0006922	obsolete cleavage of lamin involved in execution phase of apoptosis(GO:0006922)
0.0	0.0	GO:0030812	negative regulation of nucleotide catabolic process(GO:0030812)
0.0	0.1	GO:0006089	lactate metabolic process(GO:0006089)
0.0	0.1	GO:0045084	positive regulation of interleukin-12 biosynthetic process(GO:0045084)
0.0	0.1	GO:0015015	heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.0	0.1	GO:0007256	activation of JNKK activity(GO:0007256)
0.0	0.1	GO:0061030	epithelial cell differentiation involved in mammary gland alveolus development(GO:0061030)
0.0	0.2	GO:0006491	N-glycan processing(GO:0006491)
0.0	0.1	GO:1901522	positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus(GO:1901522)
0.0	0.0	GO:0061154	endothelial tube morphogenesis(GO:0061154)
0.0	0.1	GO:0060999	positive regulation of dendritic spine development(GO:0060999)
0.0	0.1	GO:0018076	N-terminal peptidyl-lysine acetylation(GO:0018076)
0.0	0.1	GO:0032747	positive regulation of interleukin-23 production(GO:0032747)
0.0	0.1	GO:0033261	obsolete regulation of S phase(GO:0033261)
0.0	0.1	GO:0032790	ribosome disassembly(GO:0032790)
0.0	0.1	GO:0006556	S-adenosylmethionine biosynthetic process(GO:0006556)
0.0	0.1	GO:0014067	negative regulation of phosphatidylinositol 3-kinase signaling(GO:0014067)
0.0	0.1	GO:0061647	histone H3-K9 methylation(GO:0051567) histone H3-K9 modification(GO:0061647)
0.0	0.0	GO:0006659	phosphatidylserine biosynthetic process(GO:0006659)
0.0	0.3	GO:0045576	mast cell activation(GO:0045576)
0.0	0.1	GO:0032100	positive regulation of response to food(GO:0032097) positive regulation of appetite(GO:0032100)
0.0	0.1	GO:0007095	mitotic G2 DNA damage checkpoint(GO:0007095)
0.0	0.1	GO:0017182	peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183)
0.0	0.1	GO:0002085	inhibition of neuroepithelial cell differentiation(GO:0002085)
0.0	0.1	GO:0003077	obsolete negative regulation of diuresis(GO:0003077)
0.0	0.0	GO:0002328	pro-B cell differentiation(GO:0002328)
0.0	0.1	GO:0002478	antigen processing and presentation of exogenous peptide antigen(GO:0002478)
0.0	0.1	GO:0030540	female genitalia development(GO:0030540)
0.0	0.2	GO:0031648	protein destabilization(GO:0031648)
0.0	0.3	GO:0060330	regulation of response to interferon-gamma(GO:0060330) regulation of interferon-gamma-mediated signaling pathway(GO:0060334)
0.0	0.4	GO:0050868	negative regulation of T cell activation(GO:0050868) negative regulation of leukocyte cell-cell adhesion(GO:1903038)
0.0	0.1	GO:0000042	protein targeting to Golgi(GO:0000042) establishment of protein localization to Golgi(GO:0072600)
0.0	0.1	GO:0048617	embryonic foregut morphogenesis(GO:0048617)
0.0	0.1	GO:0045351	type I interferon biosynthetic process(GO:0045351)
0.0	0.1	GO:0003056	regulation of vascular smooth muscle contraction(GO:0003056)
0.0	0.0	GO:0045978	negative regulation of nucleoside metabolic process(GO:0045978) negative regulation of ATP metabolic process(GO:1903579)
0.0	0.0	GO:0002923	regulation of humoral immune response mediated by circulating immunoglobulin(GO:0002923)
0.0	0.1	GO:0010613	positive regulation of cardiac muscle hypertrophy(GO:0010613) positive regulation of muscle hypertrophy(GO:0014742)
0.0	0.0	GO:0060744	thelarche(GO:0042695) mammary gland branching involved in thelarche(GO:0060744)
0.0	0.2	GO:0043508	negative regulation of JUN kinase activity(GO:0043508)
0.0	0.1	GO:0002921	negative regulation of humoral immune response(GO:0002921)
0.0	0.1	GO:0040023	establishment of nucleus localization(GO:0040023)
0.0	0.1	GO:0043518	negative regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043518) negative regulation of signal transduction by p53 class mediator(GO:1901797)
0.0	0.0	GO:0070602	centromeric sister chromatid cohesion(GO:0070601) regulation of centromeric sister chromatid cohesion(GO:0070602)
0.0	0.1	GO:0006167	AMP biosynthetic process(GO:0006167)
0.0	0.1	GO:0050860	negative regulation of antigen receptor-mediated signaling pathway(GO:0050858) negative regulation of T cell receptor signaling pathway(GO:0050860)
0.0	0.1	GO:0008653	lipopolysaccharide metabolic process(GO:0008653)
0.0	0.1	GO:0048715	negative regulation of oligodendrocyte differentiation(GO:0048715)
0.0	0.1	GO:0001661	conditioned taste aversion(GO:0001661)
0.0	0.1	GO:0048496	maintenance of organ identity(GO:0048496)
0.0	0.0	GO:0072182	nephron tubule epithelial cell differentiation(GO:0072160) regulation of nephron tubule epithelial cell differentiation(GO:0072182) regulation of epithelial cell differentiation involved in kidney development(GO:2000696)
0.0	0.1	GO:0009301	snRNA transcription(GO:0009301)
0.0	0.1	GO:0070570	regulation of axon regeneration(GO:0048679) regulation of neuron projection regeneration(GO:0070570)
0.0	0.1	GO:0010624	regulation of Schwann cell proliferation(GO:0010624) negative regulation of Schwann cell proliferation(GO:0010626)
0.0	0.0	GO:0010587	miRNA metabolic process(GO:0010586) miRNA catabolic process(GO:0010587)
0.0	0.4	GO:0050690	regulation of defense response to virus by virus(GO:0050690)
0.0	0.1	GO:0051044	positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
0.0	0.0	GO:0070102	interleukin-6-mediated signaling pathway(GO:0070102)
0.0	0.0	GO:0006007	glucose catabolic process(GO:0006007)
0.0	0.1	GO:0010759	positive regulation of macrophage chemotaxis(GO:0010759)
0.0	0.0	GO:0042670	retinal cone cell differentiation(GO:0042670) retinal cone cell development(GO:0046549)
0.0	0.1	GO:0007158	neuron cell-cell adhesion(GO:0007158)
0.0	0.2	GO:0031146	SCF-dependent proteasomal ubiquitin-dependent protein catabolic process(GO:0031146)
0.0	0.0	GO:0021571	rhombomere 5 development(GO:0021571)
0.0	0.1	GO:0006474	N-terminal protein amino acid acetylation(GO:0006474)
0.0	0.1	GO:0010508	positive regulation of autophagy(GO:0010508)
0.0	0.0	GO:0002495	antigen processing and presentation of peptide antigen via MHC class II(GO:0002495)
0.0	0.0	GO:0070672	response to interleukin-15(GO:0070672)
0.0	0.0	GO:0070933	histone H3 deacetylation(GO:0070932) histone H4 deacetylation(GO:0070933)
0.0	0.1	GO:0000089	mitotic metaphase(GO:0000089)
0.0	0.0	GO:0045842	positive regulation of mitotic metaphase/anaphase transition(GO:0045842) positive regulation of mitotic sister chromatid separation(GO:1901970) positive regulation of metaphase/anaphase transition of cell cycle(GO:1902101)
0.0	0.1	GO:0071108	protein K48-linked deubiquitination(GO:0071108)
0.0	0.1	GO:0005513	detection of calcium ion(GO:0005513)
0.0	0.0	GO:0033632	regulation of cell-cell adhesion mediated by integrin(GO:0033632)
0.0	0.0	GO:0002320	lymphoid progenitor cell differentiation(GO:0002320)
0.0	0.0	GO:0031060	regulation of histone methylation(GO:0031060)
0.0	0.1	GO:0006689	ganglioside catabolic process(GO:0006689)
0.0	0.1	GO:0007023	post-chaperonin tubulin folding pathway(GO:0007023)
0.0	0.1	GO:0034755	iron ion transmembrane transport(GO:0034755)
0.0	0.0	GO:0097300	necroptotic process(GO:0070266) programmed necrotic cell death(GO:0097300)
0.0	0.0	GO:0007191	adenylate cyclase-activating dopamine receptor signaling pathway(GO:0007191)
0.0	0.2	GO:0016925	protein sumoylation(GO:0016925)
0.0	0.1	GO:0015937	coenzyme A biosynthetic process(GO:0015937)
0.0	0.2	GO:0032012	regulation of ARF protein signal transduction(GO:0032012)
0.0	0.1	GO:0045824	negative regulation of innate immune response(GO:0045824)
0.0	0.1	GO:0008628	hormone-mediated apoptotic signaling pathway(GO:0008628)
0.0	0.2	GO:0042776	mitochondrial ATP synthesis coupled proton transport(GO:0042776)
0.0	0.0	GO:0060219	camera-type eye photoreceptor cell differentiation(GO:0060219)
0.0	0.1	GO:0016572	histone phosphorylation(GO:0016572)
0.0	0.1	GO:0060263	regulation of respiratory burst(GO:0060263)
0.0	0.1	GO:0072531	pyrimidine-containing compound transmembrane transport(GO:0072531)
0.0	0.0	GO:0051024	positive regulation of immunoglobulin secretion(GO:0051024)
0.0	0.0	GO:1903077	negative regulation of establishment of protein localization to plasma membrane(GO:0090005) negative regulation of protein localization to plasma membrane(GO:1903077) negative regulation of protein localization to cell periphery(GO:1904376)
0.0	0.1	GO:0045730	respiratory burst(GO:0045730)
0.0	0.0	GO:0042362	fat-soluble vitamin biosynthetic process(GO:0042362)
0.0	0.0	GO:0032506	cytokinetic process(GO:0032506)
0.0	0.1	GO:0045059	positive thymic T cell selection(GO:0045059)
0.0	0.0	GO:0098754	detoxification(GO:0098754)
0.0	0.1	GO:0090205	positive regulation of cholesterol metabolic process(GO:0090205)
0.0	0.1	GO:0060017	parathyroid gland development(GO:0060017)
0.0	0.0	GO:0001831	trophectodermal cellular morphogenesis(GO:0001831)
0.0	0.0	GO:0007000	nucleolus organization(GO:0007000)
0.0	0.0	GO:0043951	negative regulation of cAMP-mediated signaling(GO:0043951)
0.0	0.1	GO:0007168	receptor guanylyl cyclase signaling pathway(GO:0007168)
0.0	0.1	GO:0000730	DNA recombinase assembly(GO:0000730) double-strand break repair via synthesis-dependent strand annealing(GO:0045003)
0.0	0.0	GO:0003402	planar cell polarity pathway involved in axis elongation(GO:0003402)
0.0	0.0	GO:0006154	adenosine catabolic process(GO:0006154)
0.0	0.0	GO:0048291	isotype switching to IgG isotypes(GO:0048291)
0.0	0.0	GO:0034626	fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.0	0.1	GO:0021561	facial nerve development(GO:0021561)
0.0	0.0	GO:0006610	ribosomal protein import into nucleus(GO:0006610)
0.0	0.1	GO:0015671	oxygen transport(GO:0015671)
0.0	0.1	GO:0006269	DNA replication, synthesis of RNA primer(GO:0006269)
0.0	0.1	GO:0016265	obsolete death(GO:0016265)
0.0	0.0	GO:0043383	negative T cell selection(GO:0043383)
0.0	0.1	GO:0033169	histone H3-K9 demethylation(GO:0033169)
0.0	0.1	GO:0051085	chaperone mediated protein folding requiring cofactor(GO:0051085)
0.0	0.0	GO:0034244	negative regulation of DNA-templated transcription, elongation(GO:0032785) negative regulation of transcription elongation from RNA polymerase II promoter(GO:0034244)
0.0	0.1	GO:0000270	peptidoglycan metabolic process(GO:0000270) peptidoglycan catabolic process(GO:0009253)
0.0	0.1	GO:0035020	regulation of Rac protein signal transduction(GO:0035020)
0.0	0.0	GO:0050849	negative regulation of calcium-mediated signaling(GO:0050849)
0.0	0.0	GO:0042535	positive regulation of tumor necrosis factor biosynthetic process(GO:0042535)
0.0	0.1	GO:0008595	tripartite regional subdivision(GO:0007351) anterior/posterior axis specification, embryo(GO:0008595)
0.0	0.1	GO:0006685	sphingomyelin catabolic process(GO:0006685)
0.0	0.0	GO:0060586	multicellular organismal iron ion homeostasis(GO:0060586)
0.0	0.0	GO:0040016	embryonic cleavage(GO:0040016)
0.0	0.0	GO:0002369	T cell cytokine production(GO:0002369) positive regulation of T cell cytokine production(GO:0002726)
0.0	0.2	GO:0051923	sulfation(GO:0051923)
0.0	0.1	GO:0007035	vacuolar acidification(GO:0007035)
0.0	0.1	GO:0006528	asparagine metabolic process(GO:0006528)
0.0	0.0	GO:0006432	phenylalanyl-tRNA aminoacylation(GO:0006432)
0.0	0.0	GO:0045002	DNA double-strand break processing involved in repair via single-strand annealing(GO:0010792) double-strand break repair via single-strand annealing(GO:0045002)
0.0	0.0	GO:0006422	aspartyl-tRNA aminoacylation(GO:0006422)
0.0	0.0	GO:0032875	regulation of DNA endoreduplication(GO:0032875) negative regulation of DNA endoreduplication(GO:0032876) DNA endoreduplication(GO:0042023)
0.0	0.1	GO:0051290	protein heterotetramerization(GO:0051290)
0.0	0.1	GO:1901072	amino sugar catabolic process(GO:0046348) glucosamine-containing compound catabolic process(GO:1901072)
0.0	0.0	GO:0070837	dehydroascorbic acid transport(GO:0070837)
0.0	0.0	GO:0001992	regulation of systemic arterial blood pressure by vasopressin(GO:0001992)
0.0	0.1	GO:0006111	regulation of gluconeogenesis(GO:0006111)
0.0	0.1	GO:0046329	negative regulation of JNK cascade(GO:0046329)
0.0	0.0	GO:0048711	positive regulation of astrocyte differentiation(GO:0048711)
0.0	0.0	GO:0010980	regulation of vitamin D 24-hydroxylase activity(GO:0010979) positive regulation of vitamin D 24-hydroxylase activity(GO:0010980)
0.0	0.0	GO:0090201	negative regulation of mitochondrion organization(GO:0010823) negative regulation of release of cytochrome c from mitochondria(GO:0090201) negative regulation of apoptotic signaling pathway(GO:2001234)
0.0	0.0	GO:0045875	negative regulation of sister chromatid cohesion(GO:0045875)
0.0	0.0	GO:2000192	negative regulation of plasma membrane long-chain fatty acid transport(GO:0010748) negative regulation of anion transmembrane transport(GO:1903960) negative regulation of fatty acid transport(GO:2000192)
0.0	0.0	GO:0051970	negative regulation of transmission of nerve impulse(GO:0051970)
0.0	0.0	GO:0006855	drug transmembrane transport(GO:0006855)
0.0	0.1	GO:0070493	thrombin receptor signaling pathway(GO:0070493)
0.0	0.0	GO:0009221	pyrimidine deoxyribonucleotide biosynthetic process(GO:0009221)
0.0	0.0	GO:0007100	mitotic centrosome separation(GO:0007100)
0.0	0.0	GO:0045343	MHC class I biosynthetic process(GO:0045341) regulation of MHC class I biosynthetic process(GO:0045343)
0.0	0.0	GO:0007343	egg activation(GO:0007343)
0.0	0.0	GO:0021615	glossopharyngeal nerve development(GO:0021563) glossopharyngeal nerve morphogenesis(GO:0021615)
0.0	0.0	GO:0031936	negative regulation of chromatin silencing(GO:0031936)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.4	GO:0001891	phagocytic cup(GO:0001891)
0.0	0.1	GO:0000306	extrinsic component of vacuolar membrane(GO:0000306) extrinsic component of endosome membrane(GO:0031313)
0.0	0.1	GO:0001940	male pronucleus(GO:0001940)
0.0	0.1	GO:0070022	transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.0	0.2	GO:0070775	H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.0	0.1	GO:0005826	actomyosin contractile ring(GO:0005826)
0.0	0.1	GO:0032009	early phagosome(GO:0032009)
0.0	0.1	GO:0008540	proteasome regulatory particle, base subcomplex(GO:0008540)
0.0	0.2	GO:0031527	filopodium membrane(GO:0031527)
0.0	0.1	GO:0031088	platelet dense granule membrane(GO:0031088)
0.0	0.3	GO:0042101	T cell receptor complex(GO:0042101)
0.0	0.3	GO:0001772	immunological synapse(GO:0001772)
0.0	0.1	GO:0032444	activin responsive factor complex(GO:0032444)
0.0	0.1	GO:0031235	intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.0	0.1	GO:0043218	compact myelin(GO:0043218)
0.0	0.2	GO:0016585	obsolete chromatin remodeling complex(GO:0016585)
0.0	0.1	GO:0034045	pre-autophagosomal structure membrane(GO:0034045)
0.0	0.3	GO:0010494	cytoplasmic stress granule(GO:0010494)
0.0	0.3	GO:0005942	phosphatidylinositol 3-kinase complex(GO:0005942)
0.0	0.1	GO:0000275	mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275)
0.0	0.1	GO:0033011	perinuclear theca(GO:0033011)
0.0	0.1	GO:0005658	alpha DNA polymerase:primase complex(GO:0005658)
0.0	0.1	GO:0000164	protein phosphatase type 1 complex(GO:0000164)
0.0	0.1	GO:0005954	calcium- and calmodulin-dependent protein kinase complex(GO:0005954)
0.0	0.1	GO:0042583	chromaffin granule(GO:0042583) chromaffin granule membrane(GO:0042584)
0.0	0.2	GO:0042597	outer membrane-bounded periplasmic space(GO:0030288) periplasmic space(GO:0042597)
0.0	0.2	GO:0035098	ESC/E(Z) complex(GO:0035098)
0.0	0.1	GO:0005736	DNA-directed RNA polymerase I complex(GO:0005736)
0.0	0.0	GO:0002142	stereocilia coupling link(GO:0002139) stereocilia ankle link(GO:0002141) stereocilia ankle link complex(GO:0002142)
0.0	0.0	GO:0005896	interleukin-6 receptor complex(GO:0005896)
0.0	0.0	GO:0031205	endoplasmic reticulum Sec complex(GO:0031205)
0.0	0.1	GO:0072357	PTW/PP1 phosphatase complex(GO:0072357)
0.0	0.1	GO:0000791	euchromatin(GO:0000791)
0.0	0.0	GO:0072487	MSL complex(GO:0072487)
0.0	0.0	GO:0071438	invadopodium membrane(GO:0071438)
0.0	0.0	GO:0000942	condensed nuclear chromosome outer kinetochore(GO:0000942)
0.0	0.0	GO:0001652	granular component(GO:0001652)
0.0	0.1	GO:0097526	U4/U6 x U5 tri-snRNP complex(GO:0046540) spliceosomal tri-snRNP complex(GO:0097526)
0.0	0.1	GO:0090533	cation-transporting ATPase complex(GO:0090533)
0.0	0.0	GO:0044462	external encapsulating structure part(GO:0044462)
0.0	0.1	GO:0019773	proteasome core complex, alpha-subunit complex(GO:0019773)
0.0	0.1	GO:0071778	obsolete WINAC complex(GO:0071778)
0.0	0.1	GO:0000153	cytoplasmic ubiquitin ligase complex(GO:0000153)
0.0	0.1	GO:0043209	myelin sheath(GO:0043209)
0.0	0.0	GO:0030008	TRAPP complex(GO:0030008)
0.0	0.0	GO:0016939	kinesin II complex(GO:0016939)
0.0	0.2	GO:0034362	low-density lipoprotein particle(GO:0034362)
0.0	0.1	GO:0031264	death-inducing signaling complex(GO:0031264)
0.0	0.1	GO:0035189	Rb-E2F complex(GO:0035189)
0.0	0.1	GO:0043190	ATP-binding cassette (ABC) transporter complex(GO:0043190)
0.0	0.1	GO:0031083	BLOC complex(GO:0031082) BLOC-1 complex(GO:0031083)
0.0	0.1	GO:0045120	pronucleus(GO:0045120)
0.0	0.1	GO:0032590	dendrite membrane(GO:0032590)
0.0	0.0	GO:0070552	BRISC complex(GO:0070552)
0.0	0.0	GO:0005672	transcription factor TFIIA complex(GO:0005672)
0.0	0.1	GO:0005869	dynactin complex(GO:0005869)
0.0	0.1	GO:0071564	npBAF complex(GO:0071564)
0.0	0.1	GO:0061202	clathrin-sculpted gamma-aminobutyric acid transport vesicle(GO:0061200) clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane(GO:0061202)
0.0	0.1	GO:0030130	clathrin coat of trans-Golgi network vesicle(GO:0030130)
0.0	0.1	GO:0000276	mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.0	0.3	GO:0005626	obsolete insoluble fraction(GO:0005626)
0.0	0.0	GO:0070688	MLL5-L complex(GO:0070688)
0.0	0.2	GO:0005776	autophagosome(GO:0005776)
0.0	0.1	GO:0000145	exocyst(GO:0000145)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.3	GO:0016309	1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
0.1	0.3	GO:0052813	phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) phosphatidylinositol bisphosphate kinase activity(GO:0052813)
0.1	0.2	GO:0035184	histone threonine kinase activity(GO:0035184)
0.1	0.2	GO:0003836	beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.1	0.5	GO:0016493	C-C chemokine receptor activity(GO:0016493)
0.0	0.2	GO:0047238	glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity(GO:0047238)
0.0	0.1	GO:0005094	Rho GDP-dissociation inhibitor activity(GO:0005094)
0.0	0.1	GO:0047894	flavonol 3-sulfotransferase activity(GO:0047894)
0.0	0.3	GO:0016494	C-X-C chemokine receptor activity(GO:0016494)
0.0	0.1	GO:0047756	chondroitin 4-sulfotransferase activity(GO:0047756)
0.0	0.1	GO:0008454	alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.0	0.1	GO:0004911	interleukin-2 receptor activity(GO:0004911)
0.0	0.1	GO:0033691	sialic acid binding(GO:0033691)
0.0	0.2	GO:0030284	estrogen receptor activity(GO:0030284)
0.0	0.1	GO:0030375	thyroid hormone receptor coactivator activity(GO:0030375)
0.0	0.9	GO:0045028	G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.0	0.4	GO:0004697	protein kinase C activity(GO:0004697)
0.0	0.1	GO:0051734	ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity(GO:0046404) polydeoxyribonucleotide kinase activity(GO:0051733) ATP-dependent polynucleotide kinase activity(GO:0051734)
0.0	0.1	GO:0016314	phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity(GO:0016314)
0.0	0.1	GO:0015252	hydrogen ion channel activity(GO:0015252)
0.0	0.1	GO:0004904	interferon receptor activity(GO:0004904)
0.0	0.1	GO:0015925	galactosidase activity(GO:0015925)
0.0	0.1	GO:0047631	ADP-ribose diphosphatase activity(GO:0047631)
0.0	0.1	GO:0031705	bombesin receptor binding(GO:0031705) endothelin B receptor binding(GO:0031708)
0.0	0.2	GO:0034593	phosphatidylinositol bisphosphate phosphatase activity(GO:0034593)
0.0	0.1	GO:0035197	siRNA binding(GO:0035197)
0.0	0.1	GO:0004465	lipoprotein lipase activity(GO:0004465)
0.0	0.1	GO:0016004	phospholipase activator activity(GO:0016004)
0.0	0.1	GO:0003886	DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.0	0.1	GO:0046974	histone methyltransferase activity (H3-K9 specific)(GO:0046974)
0.0	0.1	GO:0016842	amidine-lyase activity(GO:0016842)
0.0	0.2	GO:0001784	phosphotyrosine binding(GO:0001784)
0.0	0.1	GO:0019911	structural constituent of myelin sheath(GO:0019911)
0.0	0.1	GO:0003987	acetate-CoA ligase activity(GO:0003987)
0.0	0.1	GO:0004974	leukotriene receptor activity(GO:0004974)
0.0	0.1	GO:0004950	G-protein coupled chemoattractant receptor activity(GO:0001637) chemokine receptor activity(GO:0004950)
0.0	0.1	GO:0070053	thrombospondin receptor activity(GO:0070053)
0.0	0.2	GO:0004691	cAMP-dependent protein kinase activity(GO:0004691)
0.0	0.1	GO:0008545	JUN kinase kinase activity(GO:0008545)
0.0	0.1	GO:0008745	N-acetylmuramoyl-L-alanine amidase activity(GO:0008745)
0.0	1.2	GO:0005070	SH3/SH2 adaptor activity(GO:0005070)
0.0	0.5	GO:0005164	tumor necrosis factor receptor binding(GO:0005164)
0.0	0.2	GO:0008553	hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.0	0.1	GO:0004949	cannabinoid receptor activity(GO:0004949)
0.0	0.1	GO:0005131	growth hormone receptor binding(GO:0005131)
0.0	0.1	GO:0042834	peptidoglycan binding(GO:0042834)
0.0	0.1	GO:0004351	glutamate decarboxylase activity(GO:0004351)
0.0	0.1	GO:0004449	isocitrate dehydrogenase (NAD+) activity(GO:0004449)
0.0	0.1	GO:0030368	interleukin-17 receptor activity(GO:0030368)
0.0	0.1	GO:0043141	ATP-dependent 5'-3' DNA helicase activity(GO:0043141)
0.0	0.8	GO:0004715	non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.0	0.1	GO:0031957	very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.0	0.1	GO:0004525	ribonuclease III activity(GO:0004525) double-stranded RNA-specific ribonuclease activity(GO:0032296)
0.0	0.1	GO:0004476	mannose-6-phosphate isomerase activity(GO:0004476)
0.0	0.3	GO:0004115	3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0	0.1	GO:0008321	Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.0	0.0	GO:0046935	1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.0	0.0	GO:0019959	C-X-C chemokine binding(GO:0019958) interleukin-8 binding(GO:0019959)
0.0	0.1	GO:0051400	BH domain binding(GO:0051400)
0.0	0.1	GO:0004176	ATP-dependent peptidase activity(GO:0004176)
0.0	0.3	GO:0019198	transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.0	0.1	GO:0003953	NAD+ nucleosidase activity(GO:0003953)
0.0	0.1	GO:0004957	prostaglandin E receptor activity(GO:0004957)
0.0	0.1	GO:0004969	histamine receptor activity(GO:0004969)
0.0	0.1	GO:0008109	N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109)
0.0	0.1	GO:0005132	type I interferon receptor binding(GO:0005132)
0.0	0.1	GO:0050700	CARD domain binding(GO:0050700)
0.0	0.1	GO:0008159	obsolete positive transcription elongation factor activity(GO:0008159)
0.0	0.1	GO:0005381	iron ion transmembrane transporter activity(GO:0005381)
0.0	0.0	GO:0045118	azole transporter activity(GO:0045118) azole transmembrane transporter activity(GO:1901474)
0.0	0.1	GO:0050321	tau-protein kinase activity(GO:0050321)
0.0	0.1	GO:0031628	opioid receptor binding(GO:0031628)
0.0	0.1	GO:1990939	ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574) ATP-dependent microtubule motor activity(GO:1990939)
0.0	0.1	GO:0030955	potassium ion binding(GO:0030955)
0.0	0.2	GO:0017025	TBP-class protein binding(GO:0017025)
0.0	0.1	GO:0004802	transketolase activity(GO:0004802)
0.0	0.2	GO:0032452	histone demethylase activity(GO:0032452)
0.0	0.1	GO:0031701	angiotensin receptor binding(GO:0031701)
0.0	0.1	GO:0004719	protein-L-isoaspartate (D-aspartate) O-methyltransferase activity(GO:0004719)
0.0	0.1	GO:0016748	succinyltransferase activity(GO:0016748)
0.0	0.1	GO:0016520	growth hormone-releasing hormone receptor activity(GO:0016520)
0.0	0.1	GO:0005522	profilin binding(GO:0005522)
0.0	0.1	GO:0004046	aminoacylase activity(GO:0004046)
0.0	0.1	GO:0008467	[heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.0	0.1	GO:0008518	reduced folate carrier activity(GO:0008518)
0.0	0.0	GO:0005275	amine transmembrane transporter activity(GO:0005275)
0.0	0.0	GO:0043398	HLH domain binding(GO:0043398)
0.0	0.1	GO:0004340	glucokinase activity(GO:0004340)
0.0	0.0	GO:0005113	patched binding(GO:0005113)
0.0	0.4	GO:0004435	phosphatidylinositol phospholipase C activity(GO:0004435)
0.0	0.0	GO:0042799	histone methyltransferase activity (H4-K20 specific)(GO:0042799)
0.0	0.1	GO:0015355	secondary active monocarboxylate transmembrane transporter activity(GO:0015355)
0.0	0.0	GO:0016361	activin receptor activity, type I(GO:0016361)
0.0	0.2	GO:0005095	GTPase inhibitor activity(GO:0005095)
0.0	0.0	GO:0071208	histone pre-mRNA DCP binding(GO:0071208)
0.0	0.0	GO:0008331	high voltage-gated calcium channel activity(GO:0008331)
0.0	0.1	GO:0005338	nucleotide-sugar transmembrane transporter activity(GO:0005338)
0.0	0.1	GO:0001727	lipid kinase activity(GO:0001727)
0.0	0.1	GO:0035252	UDP-xylosyltransferase activity(GO:0035252) xylosyltransferase activity(GO:0042285)
0.0	0.1	GO:0043325	phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.0	0.0	GO:0003909	DNA ligase activity(GO:0003909) DNA ligase (ATP) activity(GO:0003910)
0.0	0.1	GO:0004028	3-chloroallyl aldehyde dehydrogenase activity(GO:0004028)
0.0	0.0	GO:0004370	glycerol kinase activity(GO:0004370)
0.0	0.1	GO:0004704	NF-kappaB-inducing kinase activity(GO:0004704)
0.0	0.1	GO:0019136	deoxynucleoside kinase activity(GO:0019136)
0.0	0.0	GO:0005176	ErbB-2 class receptor binding(GO:0005176)
0.0	0.1	GO:0001671	ATPase activator activity(GO:0001671)
0.0	0.1	GO:0005000	vasopressin receptor activity(GO:0005000)
0.0	0.1	GO:0004826	phenylalanine-tRNA ligase activity(GO:0004826)
0.0	0.2	GO:0043621	protein self-association(GO:0043621)
0.0	0.1	GO:0004457	lactate dehydrogenase activity(GO:0004457)
0.0	0.1	GO:0004908	interleukin-1 receptor activity(GO:0004908)
0.0	0.1	GO:0043024	ribosomal small subunit binding(GO:0043024)
0.0	0.1	GO:0008266	poly(U) RNA binding(GO:0008266)
0.0	0.0	GO:0004311	farnesyltranstransferase activity(GO:0004311)
0.0	0.1	GO:0051766	inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440) inositol trisphosphate kinase activity(GO:0051766)
0.0	0.1	GO:0019864	IgG binding(GO:0019864)
0.0	0.1	GO:0004726	non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.0	0.1	GO:0003828	alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.0	0.0	GO:0000064	L-ornithine transmembrane transporter activity(GO:0000064)
0.0	0.0	GO:0048156	tau protein binding(GO:0048156)
0.0	0.2	GO:0030159	receptor signaling complex scaffold activity(GO:0030159)
0.0	0.1	GO:0043425	bHLH transcription factor binding(GO:0043425)
0.0	0.1	GO:0050431	transforming growth factor beta binding(GO:0050431)
0.0	0.1	GO:0030169	low-density lipoprotein particle binding(GO:0030169)
0.0	0.1	GO:0003785	actin monomer binding(GO:0003785)
0.0	0.2	GO:0001540	beta-amyloid binding(GO:0001540)
0.0	0.2	GO:0043027	cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.0	0.0	GO:0016972	thiol oxidase activity(GO:0016972)
0.0	0.1	GO:0031593	polyubiquitin binding(GO:0031593)
0.0	0.1	GO:0042975	peroxisome proliferator activated receptor binding(GO:0042975)
0.0	0.1	GO:0004708	MAP kinase kinase activity(GO:0004708)
0.0	0.0	GO:0035259	glucocorticoid receptor binding(GO:0035259)
0.0	0.3	GO:0003725	double-stranded RNA binding(GO:0003725)
0.0	0.0	GO:0001609	G-protein coupled adenosine receptor activity(GO:0001609)
0.0	0.0	GO:0051425	PTB domain binding(GO:0051425)
0.0	0.0	GO:0015562	efflux transmembrane transporter activity(GO:0015562)
0.0	0.0	GO:0033300	dehydroascorbic acid transporter activity(GO:0033300)
0.0	0.2	GO:0043499	obsolete eukaryotic cell surface binding(GO:0043499)
0.0	0.1	GO:0015924	mannosyl-oligosaccharide mannosidase activity(GO:0015924)
0.0	0.1	GO:0031624	ubiquitin conjugating enzyme binding(GO:0031624) ubiquitin-like protein conjugating enzyme binding(GO:0044390)
0.0	0.0	GO:0015057	thrombin receptor activity(GO:0015057)
0.0	0.0	GO:0003918	DNA topoisomerase type II (ATP-hydrolyzing) activity(GO:0003918) DNA topoisomerase II activity(GO:0061505)
0.0	0.0	GO:0015226	amino-acid betaine transmembrane transporter activity(GO:0015199) carnitine transmembrane transporter activity(GO:0015226)
0.0	0.2	GO:0004089	carbonate dehydratase activity(GO:0004089)
0.0	0.1	GO:0005031	tumor necrosis factor-activated receptor activity(GO:0005031)
0.0	0.1	GO:0004383	guanylate cyclase activity(GO:0004383)
0.0	0.0	GO:0004591	oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591)
0.0	0.0	GO:0008821	crossover junction endodeoxyribonuclease activity(GO:0008821)

Gene overrepresentation in curated gene sets: canonical pathways category:

Total log-likelihood	Term	Description
3.0	PID TCR PATHWAY	TCR signaling in naïve CD4+ T cells
0.4	SA PTEN PATHWAY	PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.3	ST JAK STAT PATHWAY	Jak-STAT Pathway
0.0	PID PI3KCI AKT PATHWAY	Class I PI3K signaling events mediated by Akt
0.3	PID IL5 PATHWAY	IL5-mediated signaling events
0.2	ST TYPE I INTERFERON PATHWAY	Type I Interferon (alpha/beta IFN) Pathway
0.8	PID PI3KCI PATHWAY	Class I PI3K signaling events
0.4	SA MMP CYTOKINE CONNECTION	Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.4	PID EPHRINB REV PATHWAY	Ephrin B reverse signaling
0.3	PID CD40 PATHWAY	CD40/CD40L signaling
0.6	PID BCR 5PATHWAY	BCR signaling pathway
0.1	PID TCR RAS PATHWAY	Ras signaling in the CD4+ TCR pathway
0.2	PID TCR JNK PATHWAY	JNK signaling in the CD4+ TCR pathway
0.2	PID IL2 1PATHWAY	IL2-mediated signaling events
0.2	PID ANTHRAX PATHWAY	Cellular roles of Anthrax toxin
0.4	PID IL12 STAT4 PATHWAY	IL12 signaling mediated by STAT4
0.3	PID IL2 STAT5 PATHWAY	IL2 signaling events mediated by STAT5
0.4	PID P38 MKK3 6PATHWAY	p38 MAPK signaling pathway
0.1	ST GA12 PATHWAY	G alpha 12 Pathway
0.1	PID NFKAPPAB ATYPICAL PATHWAY	Atypical NF-kappaB pathway
0.5	PID CDC42 REG PATHWAY	Regulation of CDC42 activity
0.1	PID CD8 TCR PATHWAY	TCR signaling in naïve CD8+ T cells
0.1	PID RANBP2 PATHWAY	Sumoylation by RanBP2 regulates transcriptional repression
0.1	PID NFKAPPAB CANONICAL PATHWAY	Canonical NF-kappaB pathway
0.8	PID AR TF PATHWAY	Regulation of Androgen receptor activity
0.1	ST PAC1 RECEPTOR PATHWAY	PAC1 Receptor Pathway
0.3	PID IL12 2PATHWAY	IL12-mediated signaling events
0.4	PID TXA2PATHWAY	Thromboxane A2 receptor signaling
0.2	PID FAS PATHWAY	FAS (CD95) signaling pathway
0.3	PID ERBB1 INTERNALIZATION PATHWAY	Internalization of ErbB1
0.6	PID IL4 2PATHWAY	IL4-mediated signaling events
0.3	PID CD8 TCR DOWNSTREAM PATHWAY	Downstream signaling in naïve CD8+ T cells
0.0	PID PDGFRA PATHWAY	PDGFR-alpha signaling pathway
0.0	ST GRANULE CELL SURVIVAL PATHWAY	Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway.
0.0	ST TUMOR NECROSIS FACTOR PATHWAY	Tumor Necrosis Factor Pathway.
0.0	PID CXCR3 PATHWAY	CXCR3-mediated signaling events
0.1	SA REG CASCADE OF CYCLIN EXPR	Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.3	PID INSULIN PATHWAY	Insulin Pathway
0.0	PID LPA4 PATHWAY	LPA4-mediated signaling events
0.1	PID INTEGRIN3 PATHWAY	Beta3 integrin cell surface interactions
0.1	PID IL8 CXCR2 PATHWAY	IL8- and CXCR2-mediated signaling events
0.2	PID NFAT TFPATHWAY	Calcineurin-regulated NFAT-dependent transcription in lymphocytes

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.4	REACTOME BINDING AND ENTRY OF HIV VIRION	Genes involved in Binding and entry of HIV virion
0.1	0.7	REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS	Genes involved in Signal regulatory protein (SIRP) family interactions
0.1	0.7	REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS	Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.1	0.1	REACTOME GPVI MEDIATED ACTIVATION CASCADE	Genes involved in GPVI-mediated activation cascade
0.1	0.2	REACTOME G ALPHA Z SIGNALLING EVENTS	Genes involved in G alpha (z) signalling events
0.0	1.3	REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS	Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.0	0.0	REACTOME G ALPHA1213 SIGNALLING EVENTS	Genes involved in G alpha (12/13) signalling events
0.0	0.2	REACTOME IL 7 SIGNALING	Genes involved in Interleukin-7 signaling
0.0	0.8	REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE	Genes involved in Synthesis of PIPs at the plasma membrane
0.0	0.5	REACTOME DOWNSTREAM TCR SIGNALING	Genes involved in Downstream TCR signaling
0.0	0.3	REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION	Genes involved in activated TAK1 mediates p38 MAPK activation
0.0	0.1	REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING	Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
0.0	0.0	REACTOME PROSTACYCLIN SIGNALLING THROUGH PROSTACYCLIN RECEPTOR	Genes involved in Prostacyclin signalling through prostacyclin receptor
0.0	0.0	REACTOME ADENYLATE CYCLASE INHIBITORY PATHWAY	Genes involved in Adenylate cyclase inhibitory pathway
0.0	0.3	REACTOME P2Y RECEPTORS	Genes involved in P2Y receptors
0.0	0.1	REACTOME IRAK1 RECRUITS IKK COMPLEX	Genes involved in IRAK1 recruits IKK complex
0.0	0.2	REACTOME REGULATION OF IFNG SIGNALING	Genes involved in Regulation of IFNG signaling
0.0	0.0	REACTOME G PROTEIN ACTIVATION	Genes involved in G-protein activation
0.0	0.1	REACTOME SPRY REGULATION OF FGF SIGNALING	Genes involved in Spry regulation of FGF signaling
0.0	0.2	REACTOME TRAF6 MEDIATED IRF7 ACTIVATION	Genes involved in TRAF6 mediated IRF7 activation
0.0	0.2	REACTOME NEPHRIN INTERACTIONS	Genes involved in Nephrin interactions
0.0	0.3	REACTOME N GLYCAN ANTENNAE ELONGATION	Genes involved in N-Glycan antennae elongation
0.0	0.1	REACTOME IL 6 SIGNALING	Genes involved in Interleukin-6 signaling
0.0	0.2	REACTOME NFKB ACTIVATION THROUGH FADD RIP1 PATHWAY MEDIATED BY CASPASE 8 AND10	Genes involved in NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10
0.0	0.3	REACTOME REGULATION OF IFNA SIGNALING	Genes involved in Regulation of IFNA signaling
0.0	0.2	REACTOME REGULATION OF AMPK ACTIVITY VIA LKB1	Genes involved in Regulation of AMPK activity via LKB1
0.0	0.2	REACTOME IL RECEPTOR SHC SIGNALING	Genes involved in Interleukin receptor SHC signaling
0.0	0.0	REACTOME TRAF3 DEPENDENT IRF ACTIVATION PATHWAY	Genes involved in TRAF3-dependent IRF activation pathway
0.0	0.4	REACTOME THE ROLE OF NEF IN HIV1 REPLICATION AND DISEASE PATHOGENESIS	Genes involved in The role of Nef in HIV-1 replication and disease pathogenesis
0.0	0.3	REACTOME CTLA4 INHIBITORY SIGNALING	Genes involved in CTLA4 inhibitory signaling
0.0	0.1	REACTOME REGULATION OF SIGNALING BY CBL	Genes involved in Regulation of signaling by CBL
0.0	0.2	REACTOME REGULATION OF COMPLEMENT CASCADE	Genes involved in Regulation of Complement cascade
0.0	0.1	REACTOME PLATELET SENSITIZATION BY LDL	Genes involved in Platelet sensitization by LDL
0.0	0.1	REACTOME P38MAPK EVENTS	Genes involved in p38MAPK events
0.0	0.2	REACTOME EICOSANOID LIGAND BINDING RECEPTORS	Genes involved in Eicosanoid ligand-binding receptors
0.0	0.2	REACTOME GENERATION OF SECOND MESSENGER MOLECULES	Genes involved in Generation of second messenger molecules
0.0	0.3	REACTOME DARPP 32 EVENTS	Genes involved in DARPP-32 events
0.0	0.1	REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS	Genes involved in Trafficking of GluR2-containing AMPA receptors
0.0	0.1	REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR	Genes involved in Trafficking and processing of endosomal TLR
0.0	0.0	REACTOME INHIBITION OF REPLICATION INITIATION OF DAMAGED DNA BY RB1 E2F1	Genes involved in Inhibition of replication initiation of damaged DNA by RB1/E2F1
0.0	0.1	REACTOME NOD1 2 SIGNALING PATHWAY	Genes involved in NOD1/2 Signaling Pathway
0.0	0.2	REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING	Genes involved in Formation of ATP by chemiosmotic coupling
0.0	0.7	REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL	Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0	0.2	REACTOME ZINC TRANSPORTERS	Genes involved in Zinc transporters
0.0	0.2	REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS	Genes involved in Regulation of gene expression in beta cells
0.0	0.3	REACTOME CHONDROITIN SULFATE BIOSYNTHESIS	Genes involved in Chondroitin sulfate biosynthesis
0.0	0.1	REACTOME DSCAM INTERACTIONS	Genes involved in DSCAM interactions
0.0	0.2	REACTOME INSULIN SYNTHESIS AND PROCESSING	Genes involved in Insulin Synthesis and Processing
0.0	0.2	REACTOME INFLAMMASOMES	Genes involved in Inflammasomes
0.0	0.1	REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS	Genes involved in Activation of the AP-1 family of transcription factors
0.0	0.2	REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE	Genes involved in Reversible Hydration of Carbon Dioxide
0.0	0.0	REACTOME ENDOSOMAL VACUOLAR PATHWAY	Genes involved in Endosomal/Vacuolar pathway
0.0	0.2	REACTOME COSTIMULATION BY THE CD28 FAMILY	Genes involved in Costimulation by the CD28 family
0.0	0.1	REACTOME CDC6 ASSOCIATION WITH THE ORC ORIGIN COMPLEX	Genes involved in CDC6 association with the ORC:origin complex
0.0	0.1	REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY	Genes involved in Regulation of the Fanconi anemia pathway
0.0	0.2	REACTOME G BETA GAMMA SIGNALLING THROUGH PLC BETA	Genes involved in G beta:gamma signalling through PLC beta
0.0	0.0	REACTOME NUCLEOTIDE LIKE PURINERGIC RECEPTORS	Genes involved in Nucleotide-like (purinergic) receptors
0.0	0.0	REACTOME ASSOCIATION OF LICENSING FACTORS WITH THE PRE REPLICATIVE COMPLEX	Genes involved in Association of licensing factors with the pre-replicative complex
0.0	0.0	REACTOME SIGNALING BY ERBB2	Genes involved in Signaling by ERBB2
0.0	0.1	REACTOME SHC RELATED EVENTS	Genes involved in SHC-related events
0.0	0.3	REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE	Genes involved in Sema4D induced cell migration and growth-cone collapse
0.0	0.1	REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION	Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.0	0.1	REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS	Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.0	0.0	REACTOME PEPTIDE CHAIN ELONGATION	Genes involved in Peptide chain elongation
0.0	0.1	REACTOME RAS ACTIVATION UOPN CA2 INFUX THROUGH NMDA RECEPTOR	Genes involved in Ras activation uopn Ca2+ infux through NMDA receptor
0.0	0.0	REACTOME ACTIVATION OF NF KAPPAB IN B CELLS	Genes involved in Activation of NF-kappaB in B Cells
0.0	0.3	REACTOME INTERFERON GAMMA SIGNALING	Genes involved in Interferon gamma signaling
0.0	0.1	REACTOME SYNTHESIS OF PE	Genes involved in Synthesis of PE