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ENCODE: H3K4me1 ChIP-Seq of primary human cells
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Results for NR6A1

Z-value: 0.87

Motif logo

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Transcription factors associated with NR6A1

Gene Symbol Gene ID Gene Info
NR6A1
ENSG00000148200.12 nuclear receptor subfamily 6 group A member 1

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE Gene Distance Association probability Pearson corr. coef. P-value Plot
chr9_127536416_127536567NR6A129020.1796220.881.9e-03Click!
chr9_127316512_127316663NR6A1415000.123718-0.771.4e-02Click!
chr9_127336792_127336943NR6A1212200.164299-0.751.9e-02Click!
chr9_127314112_127314350NR6A1438560.118728-0.684.3e-02Click!
chr9_127314557_127314840NR6A1433890.119713-0.684.4e-02Click!

Activity of the NR6A1 motif across conditions

Conditions sorted by the z-value of the NR6A1 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE) Target Score Top associated gene Gene Info Distance of CRE to TSS CRE/Gene association probability
chr14_72947953_72948226 0.35 RGS6
 regulator of G-protein signaling 6
 21712
 0.28
chrX_13108038_13108679 0.33 FAM9C
 family with sequence similarity 9, member C
 45557
 0.18
chr9_123652141_123652292 0.32 PHF19
 PHD finger protein 19
 12610
 0.18
chr17_72751609_72751889 0.31 SLC9A3R1
 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 1
 6393
 0.1
chr8_82019930_82020142 0.29 PAG1
 phosphoprotein associated with glycosphingolipid microdomains 1
 4267
 0.34
chr1_8488032_8488525 0.29 RP5-1115A15.1
2580
 0.27
chr15_40596685_40596954 0.29 PLCB2
 phospholipase C, beta 2
 3207
 0.11
chr21_45509890_45510158 0.28 PWP2
 PWP2 periodic tryptophan protein homolog (yeast)
 17147
 0.16
chr10_129860224_129860381 0.27 PTPRE
 protein tyrosine phosphatase, receptor type, E
 14468
 0.26
chr1_197360685_197361146 0.27 CRB1
 crumbs homolog 1 (Drosophila)
 22044
 0.23
chr19_12775707_12775982 0.27 MAN2B1
 mannosidase, alpha, class 2B, member 1
 1704
 0.14
chr1_32825530_32825738 0.25 FAM229A
 family with sequence similarity 229, member A
 1791
 0.22
chr7_148325963_148326351 0.25 C7orf33
 chromosome 7 open reading frame 33
 38500
 0.16
chr15_86128935_86129221 0.24 RP11-815J21.2
5669
 0.19
chr9_22075219_22075414 0.24 CDKN2B-AS1
 CDKN2B antisense RNA 1
 28566
 0.18
chr11_67173722_67173982 0.24 TBC1D10C
 TBC1 domain family, member 10C
 2192
 0.12
chr2_143898363_143898928 0.24 ARHGAP15
 Rho GTPase activating protein 15
 11762
 0.25
chr8_134528898_134529424 0.23 ST3GAL1
 ST3 beta-galactoside alpha-2,3-sialyltransferase 1
 17535
 0.28
chr9_92151633_92152777 0.23 SEMA4D
 sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D
 39160
 0.16
chr1_206755327_206755741 0.23 RASSF5
 Ras association (RalGDS/AF-6) domain family member 5
 25041
 0.13
chr1_54946013_54946309 0.23 ENSG00000265404
 .
 24180
 0.16
chr3_16556525_16556706 0.22 RFTN1
 raftlin, lipid raft linker 1
 1082
 0.63
chr16_17545376_17545755 0.22 XYLT1
 xylosyltransferase I
 19173
 0.3
chr1_206747367_206748212 0.22 RASSF5
 Ras association (RalGDS/AF-6) domain family member 5
 17296
 0.15
chr17_14233383_14233629 0.21 HS3ST3B1
 heparan sulfate (glucosamine) 3-O-sulfotransferase 3B1
 29106
 0.23
chr3_46411481_46411895 0.21 CCR5
 chemokine (C-C motif) receptor 5 (gene/pseudogene)
 55
 0.97
chr18_60806585_60806736 0.21 RP11-299P2.1
11893
 0.25
chr6_90981736_90981993 0.21 BACH2
 BTB and CNC homology 1, basic leucine zipper transcription factor 2
 24597
 0.22
chr2_136895658_136895809 0.21 CXCR4
 chemokine (C-X-C motif) receptor 4
 19998
 0.26
chr9_117701644_117701992 0.21 TNFSF8
 tumor necrosis factor (ligand) superfamily, member 8
 9121
 0.28
chrX_13102950_13103119 0.21 FAM9C
 family with sequence similarity 9, member C
 40233
 0.19
chr1_111421634_111421896 0.21 CD53
 CD53 molecule
 5989
 0.21
chr21_32736198_32736388 0.21 TIAM1
 T-cell lymphoma invasion and metastasis 1
 19699
 0.27
chr1_209925627_209925957 0.21 TRAF3IP3
 TRAF3 interacting protein 3
 3585
 0.18
chr4_143622207_143622596 0.21 INPP4B
 inositol polyphosphate-4-phosphatase, type II, 105kDa
 140579
 0.05
chr5_118645803_118646226 0.20 ENSG00000243333
 .
 3688
 0.25
chr9_134146913_134147198 0.20 FAM78A
 family with sequence similarity 78, member A
 1145
 0.48
chr2_196423126_196423304 0.20 SLC39A10
 solute carrier family 39 (zinc transporter), member 10
 17486
 0.24
chrX_20458891_20459042 0.20 ENSG00000252978
 .
 11260
 0.3
chrX_40138916_40139203 0.20 ENSG00000238920
 .
 5290
 0.32
chr3_187696963_187697463 0.20 LPP
 LIM domain containing preferred translocation partner in lipoma
 173859
 0.03
chr15_60836979_60837190 0.20 CTD-2501E16.2
14912
 0.19
chr8_71275992_71276158 0.20 ENSG00000207036
 .
 6493
 0.25
chrX_134518932_134519216 0.20 ZNF449
 zinc finger protein 449
 40353
 0.13
chr18_43620867_43621135 0.20 PSTPIP2
 proline-serine-threonine phosphatase interacting protein 2
 31222
 0.13
chr10_22899051_22899369 0.20 PIP4K2A
 phosphatidylinositol-5-phosphate 4-kinase, type II, alpha
 18568
 0.27
chr15_85141859_85142174 0.20 ZSCAN2
 zinc finger and SCAN domain containing 2
 2201
 0.19
chrX_135848042_135848429 0.20 ARHGEF6
 Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6
 1267
 0.45
chr9_130623880_130624317 0.19 ENG
 endoglin
 7063
 0.08
chr17_27228319_27228798 0.19 DHRS13
 dehydrogenase/reductase (SDR family) member 13
 1425
 0.19
chr18_60880832_60881273 0.19 ENSG00000238988
 .
 19154
 0.21
chr17_33543338_33543516 0.19 RP11-799D4.4
21573
 0.11
chr11_67173408_67173659 0.19 TBC1D10C
 TBC1 domain family, member 10C
 1873
 0.13
chr11_128608264_128608441 0.19 FLI1
 Fli-1 proto-oncogene, ETS transcription factor
 26333
 0.17
chr10_11224652_11224918 0.19 RP3-323N1.2
11446
 0.22
chr16_27240742_27240893 0.19 NSMCE1
 non-SMC element 1 homolog (S. cerevisiae)
 3582
 0.21
chr10_7233978_7234351 0.19 SFMBT2
 Scm-like with four mbt domains 2
 216543
 0.02
chr17_3863445_3863626 0.19 ATP2A3
 ATPase, Ca++ transporting, ubiquitous
 4050
 0.22
chr4_143617070_143617312 0.19 INPP4B
 inositol polyphosphate-4-phosphatase, type II, 105kDa
 135369
 0.06
chr1_11789201_11789352 0.19 AGTRAP
 angiotensin II receptor-associated protein
 6865
 0.13
chr2_240219157_240219354 0.19 ENSG00000265215
 .
 7902
 0.19
chr1_232715110_232715328 0.19 SIPA1L2
 signal-induced proliferation-associated 1 like 2
 17915
 0.28
chr20_31554218_31554478 0.19 EFCAB8
 EF-hand calcium binding domain 8
 6697
 0.17
chr1_206945881_206946032 0.19 IL10
 interleukin 10
 117
 0.96
chr1_159037154_159037495 0.19 ENSG00000265589
 .
 8285
 0.18
chr16_85342323_85342695 0.19 ENSG00000266307
 .
 2578
 0.35
chr1_169575119_169575302 0.19 SELP
 selectin P (granule membrane protein 140kDa, antigen CD62)
 13247
 0.2
chrX_42259008_42259366 0.19 ENSG00000206896
 .
 225549
 0.02
chr10_11203289_11203522 0.19 CELF2
 CUGBP, Elav-like family member 2
 3588
 0.26
chr2_28570986_28571140 0.19 AC093690.1
37737
 0.13
chr1_167602468_167602965 0.18 RP3-455J7.4
2805
 0.25
chr7_50257067_50257311 0.18 AC020743.2
74770
 0.1
chr4_6920362_6920560 0.18 TBC1D14
 TBC1 domain family, member 14
 8486
 0.18
chr14_91855068_91855898 0.18 CCDC88C
 coiled-coil domain containing 88C
 28207
 0.19
chr20_47782632_47782783 0.18 STAU1
 staufen double-stranded RNA binding protein 1
 8093
 0.21
chr5_130731828_130731979 0.18 CDC42SE2
 CDC42 small effector 2
 10604
 0.3
chr6_52200307_52200580 0.18 PAQR8
 progestin and adipoQ receptor family member VIII
 25776
 0.19
chr1_12231932_12232095 0.18 TNFRSF1B
 tumor necrosis factor receptor superfamily, member 1B
 4953
 0.18
chr16_28622056_28622448 0.18 SULT1A1
 sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1
 899
 0.46
chr3_60090466_60090753 0.18 NPCDR1
 nasopharyngeal carcinoma, down-regulated 1
 133026
 0.06
chr6_41170433_41170835 0.18 TREML2
 triggering receptor expressed on myeloid cells-like 2
 1702
 0.26
chr9_130473685_130473878 0.18 C9orf117
 chromosome 9 open reading frame 117
 388
 0.73
chr17_75925692_75925843 0.18 ENSG00000238898
 .
 9587
 0.22
chr12_53602242_53602592 0.18 ITGB7
 integrin, beta 7
 1326
 0.29
chr12_64992774_64993476 0.18 RP11-338E21.1
10114
 0.13
chr11_128162482_128162771 0.18 ETS1
 v-ets avian erythroblastosis virus E26 oncogene homolog 1
 212663
 0.02
chr13_41176876_41177104 0.18 FOXO1
 forkhead box O1
 63744
 0.11
chr12_92756626_92757039 0.18 RP11-693J15.4
58475
 0.12
chr10_26745731_26745940 0.18 APBB1IP
 amyloid beta (A4) precursor protein-binding, family B, member 1 interacting protein
 18481
 0.24
chr3_56823289_56823680 0.18 ARHGEF3
 Rho guanine nucleotide exchange factor (GEF) 3
 12493
 0.28
chr5_131744783_131745111 0.18 C5orf56
 chromosome 5 open reading frame 56
 1381
 0.32
chr21_44819666_44819955 0.18 SIK1
 salt-inducible kinase 1
 27198
 0.24
chr10_6585736_6586147 0.18 PRKCQ
 protein kinase C, theta
 36260
 0.23
chr6_41975005_41975289 0.18 ENSG00000206875
 .
 11105
 0.16
chr6_14373007_14373158 0.18 ENSG00000238987
 .
 216389
 0.02
chr13_95836619_95836770 0.18 ENSG00000238463
 .
 25904
 0.23
chr1_229170121_229170313 0.18 RP5-1061H20.5
193092
 0.02
chr1_65330970_65331121 0.18 RAVER2
 ribonucleoprotein, PTB-binding 2
 87298
 0.09
chr2_234177577_234177728 0.18 ENSG00000252010
 .
 6721
 0.15
chr5_75770152_75770552 0.18 IQGAP2
 IQ motif containing GTPase activating protein 2
 70103
 0.12
chr6_53109375_53109667 0.18 ENSG00000206908
 .
 25462
 0.15
chr19_7411370_7411784 0.18 CTB-133G6.1
2271
 0.26
chr1_112054315_112054681 0.18 ADORA3
 adenosine A3 receptor
 8116
 0.13
chr2_60780651_60780821 0.18 BCL11A
 B-cell CLL/lymphoma 11A (zinc finger protein)
 34
 0.98
chr10_6583895_6584058 0.18 PRKCQ
 protein kinase C, theta
 38225
 0.22
chr10_11193217_11193852 0.18 CELF2
 CUGBP, Elav-like family member 2
 13459
 0.2
chr14_24807724_24807962 0.18 RIPK3
 receptor-interacting serine-threonine kinase 3
 1235
 0.19
chr21_36401379_36401530 0.18 RUNX1
 runt-related transcription factor 1
 20008
 0.29
chr8_103121247_103121419 0.18 NCALD
 neurocalcin delta
 14845
 0.21
chr6_52241496_52241889 0.18 PAQR8
 progestin and adipoQ receptor family member VIII
 14448
 0.22
chrX_70318458_70318852 0.17 FOXO4
 forkhead box O4
 2276
 0.17
chr5_76152388_76152629 0.17 S100Z
 S100 calcium binding protein Z
 6584
 0.18
chr17_38760477_38760676 0.17 SMARCE1
 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 1
 27966
 0.12
chr6_24962302_24962654 0.17 FAM65B
 family with sequence similarity 65, member B
 26290
 0.19
chr8_145085888_145086183 0.17 SPATC1
 spermatogenesis and centriole associated 1
 547
 0.47
chr13_110222272_110222771 0.17 LINC00676
 long intergenic non-protein coding RNA 676
 158108
 0.04
chr1_27165220_27165588 0.17 ZDHHC18
 zinc finger, DHHC-type containing 18
 6893
 0.12
chr3_52303914_52304065 0.17 ENSG00000199150
 .
 1610
 0.2
chr8_131025939_131026245 0.17 FAM49B
 family with sequence similarity 49, member B
 2559
 0.24
chr19_13993263_13993689 0.17 NANOS3
 nanos homolog 3 (Drosophila)
 5413
 0.09
chr4_129783038_129783517 0.17 JADE1
 jade family PHD finger 1
 30689
 0.24
chr1_100830416_100830661 0.17 CDC14A
 cell division cycle 14A
 12033
 0.18
chr3_187676645_187676932 0.17 LPP
 LIM domain containing preferred translocation partner in lipoma
 194284
 0.03
chr4_99367280_99367535 0.17 RP11-724M22.1
50108
 0.16
chr17_74148395_74148576 0.17 RNF157-AS1
 RNF157 antisense RNA 1
 1308
 0.31
chr3_16880178_16880359 0.17 PLCL2
 phospholipase C-like 2
 46184
 0.18
chr14_104855874_104856139 0.17 ENSG00000222761
 .
 11379
 0.26
chr2_109833807_109834002 0.17 ENSG00000264934
 .
 75860
 0.1
chr20_5623012_5623187 0.17 GPCPD1
 glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae)
 31427
 0.21
chr7_69068510_69068661 0.17 AUTS2
 autism susceptibility candidate 2
 3988
 0.32
chr19_39107432_39107629 0.17 MAP4K1
 mitogen-activated protein kinase kinase kinase kinase 1
 1034
 0.37
chr11_110709081_110709232 0.17 ARHGAP20
 Rho GTPase activating protein 20
 125244
 0.06
chr3_177662901_177663156 0.17 ENSG00000199858
 .
 62539
 0.16
chr14_61909696_61909971 0.17 PRKCH
 protein kinase C, eta
 557
 0.83
chr8_19554391_19555213 0.17 CSGALNACT1
 chondroitin sulfate N-acetylgalactosaminyltransferase 1
 14530
 0.29
chr4_4420478_4420740 0.17 NSG1
 Homo sapiens neuron specific gene family member 1 (NSG1), transcript variant 3, mRNA.
 31777
 0.16
chr19_16229174_16229347 0.17 RAB8A
 RAB8A, member RAS oncogene family
 6553
 0.14
chr9_92056751_92057221 0.17 SEMA4D
 sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D
 5588
 0.27
chr1_160579528_160579679 0.17 CD84
 CD84 molecule
 30297
 0.12
chr10_11237002_11237580 0.17 RP3-323N1.2
23952
 0.2
chr2_191934456_191934744 0.17 ENSG00000231858
 .
 48348
 0.11
chr6_15264518_15264669 0.17 JARID2
 jumonji, AT rich interactive domain 2
 15450
 0.18
chr18_2960888_2961200 0.17 RP11-737O24.1
5972
 0.16
chr5_55387236_55387387 0.17 ANKRD55
 ankyrin repeat domain 55
 25467
 0.16
chr5_67674468_67674625 0.17 PIK3R1
 phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
 86150
 0.1
chr3_16942822_16942973 0.17 PLCL2
 phospholipase C-like 2
 16445
 0.23
chr4_90208438_90208788 0.17 GPRIN3
 GPRIN family member 3
 20548
 0.27
chr10_6603625_6603862 0.17 PRKCQ
 protein kinase C, theta
 18458
 0.29
chr1_69963453_69963604 0.17 LRRC7
 leucine rich repeat containing 7
 70553
 0.14
chr2_101946285_101946451 0.17 ENSG00000264857
 .
 20456
 0.16
chr8_129664945_129665222 0.17 ENSG00000221351
 .
 166957
 0.04
chr1_108741850_108742080 0.16 RP11-483I13.5
583
 0.61
chr10_17469337_17469935 0.16 ST8SIA6-AS1
 ST8SIA6 antisense RNA 1
 19610
 0.17
chr9_20228261_20228412 0.16 ENSG00000221744
 .
 66666
 0.13
chr4_109275787_109275938 0.16 ENSG00000232021
 .
 178418
 0.03
chr7_50301548_50301699 0.16 IKZF1
 IKAROS family zinc finger 1 (Ikaros)
 42701
 0.19
chr14_90147407_90147667 0.16 ENSG00000252655
 .
 30290
 0.14
chr12_57456902_57457053 0.16 MYO1A
 myosin IA
 12018
 0.1
chr1_208045857_208046008 0.16 CD34
 CD34 molecule
 17905
 0.25
chr16_21658961_21659187 0.16 IGSF6
 immunoglobulin superfamily, member 6
 4853
 0.13
chr1_17759092_17759354 0.16 RCC2
 regulator of chromosome condensation 2
 5834
 0.17
chr16_31488982_31489389 0.16 TGFB1I1
 transforming growth factor beta 1 induced transcript 1
 4438
 0.1
chr12_781338_781694 0.16 NINJ2
 ninjurin 2
 8571
 0.19
chr11_306863_307074 0.16 IFITM2
 interferon induced transmembrane protein 2
 663
 0.42
chr9_80622373_80622560 0.16 GNAQ
 guanine nucleotide binding protein (G protein), q polypeptide
 23054
 0.27
chr12_76934517_76934736 0.16 OSBPL8
 oxysterol binding protein-like 8
 18658
 0.28
chr7_150374566_150375043 0.16 GIMAP2
 GTPase, IMAP family member 2
 7984
 0.18
chr14_93124277_93124612 0.16 RIN3
 Ras and Rab interactor 3
 5598
 0.29
chr16_3126091_3126264 0.16 ENSG00000252561
 .
 6653
 0.06
chr12_12626467_12626673 0.16 DUSP16
 dual specificity phosphatase 16
 47489
 0.15
chr5_175956521_175957004 0.16 RNF44
 ring finger protein 44
 884
 0.47
chr5_75685944_75686439 0.16 IQGAP2
 IQ motif containing GTPase activating protein 2
 12883
 0.27
chr19_6654326_6654734 0.16 TNFSF14
 tumor necrosis factor (ligand) superfamily, member 14
 15598
 0.13
chr2_135425836_135426057 0.16 TMEM163
 transmembrane protein 163
 50624
 0.17
chr15_93579557_93579854 0.16 CHD2
 chromodomain helicase DNA binding protein 2
 27609
 0.2
chr2_106370179_106370624 0.16 NCK2
 NCK adaptor protein 2
 8213
 0.3
chr19_7458115_7458266 0.16 CTB-133G6.2
1735
 0.24
chr12_68848636_68848957 0.16 MDM1
 Mdm1 nuclear protein homolog (mouse)
 122635
 0.05
chr2_220112096_220112414 0.16 STK16
 serine/threonine kinase 16
 1637
 0.15
chr14_51711081_51711357 0.16 ENSG00000201376
 .
 411
 0.84
chr15_41735495_41735646 0.16 ENSG00000200407
 .
 5472
 0.16
chr7_26410221_26410372 0.16 AC004540.4
5596
 0.24
chr7_7199791_7199942 0.16 C1GALT1
 core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase, 1
 3301
 0.25
chrX_41969111_41969315 0.16 ENSG00000212560
 .
 29570
 0.22
chr12_111888335_111888486 0.16 ATXN2
 ataxin 2
 5506
 0.19
chr1_207244347_207244498 0.16 PFKFB2
 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2
 6073
 0.14
chr10_22422484_22422726 0.16 EBLN1
 endogenous Bornavirus-like nucleoprotein 1
 76345
 0.1
chr19_56143009_56143160 0.16 ZNF580
 zinc finger protein 580
 3298
 0.09
chr3_71277170_71277635 0.16 FOXP1
 forkhead box P1
 16914
 0.27
chr7_72939321_72939472 0.16 BAZ1B
 bromodomain adjacent to zinc finger domain, 1B
 2788
 0.21
chr9_117136205_117136760 0.16 AKNA
 AT-hook transcription factor
 2762
 0.28
chr19_54899589_54899740 0.16 LAIR1
 leukocyte-associated immunoglobulin-like receptor 1
 17499
 0.09
chr20_56039749_56039992 0.16 CTCFL
 CCCTC-binding factor (zinc finger protein)-like
 59443
 0.1
chr6_36139598_36139749 0.16 BRPF3
 bromodomain and PHD finger containing, 3
 24848
 0.13
chr7_148418097_148418248 0.16 ENSG00000264918
 .
 9848
 0.18
chr1_167612000_167612291 0.16 RP3-455J7.4
12234
 0.19
chrX_16612049_16612225 0.16 ENSG00000265144
 .
 33071
 0.16
chr3_105904284_105904435 0.16 CBLB
 Cbl proto-oncogene B, E3 ubiquitin protein ligase
 315963
 0.01
chr16_23868832_23868983 0.16 PRKCB
 protein kinase C, beta
 20363
 0.23
chr11_73691666_73692195 0.16 UCP2
 uncoupling protein 2 (mitochondrial, proton carrier)
 53
 0.97

Histogram of CRE-TSS distances for CREs targeted by :

Histogram of

Rank distribution of CRE target scores:

Histogram of target CRE score.

Distribution of target CREs across different genomic regions:

Weighted Piechart of Weighted Piechart of Weighted Piechart of

Network of associatons between targets according to the STRING database.

First level regulatory network of NR6A1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.5 GO:0030854 positive regulation of granulocyte differentiation(GO:0030854)
0.1 0.3 GO:0002874 regulation of chronic inflammatory response to antigenic stimulus(GO:0002874)
0.1 0.4 GO:0050857 positive regulation of antigen receptor-mediated signaling pathway(GO:0050857)
0.1 0.3 GO:0045589 regulation of regulatory T cell differentiation(GO:0045589)
0.1 0.3 GO:0046642 negative regulation of alpha-beta T cell proliferation(GO:0046642)
0.1 0.1 GO:0060557 positive regulation of vitamin metabolic process(GO:0046136) positive regulation of vitamin D biosynthetic process(GO:0060557) positive regulation of calcidiol 1-monooxygenase activity(GO:0060559)
0.1 0.2 GO:0032237 activation of store-operated calcium channel activity(GO:0032237) regulation of store-operated calcium channel activity(GO:1901339) positive regulation of store-operated calcium channel activity(GO:1901341)
0.1 0.2 GO:0019276 UDP-N-acetylgalactosamine metabolic process(GO:0019276)
0.1 0.2 GO:0042996 regulation of Golgi to plasma membrane protein transport(GO:0042996)
0.1 0.2 GO:0035405 histone-threonine phosphorylation(GO:0035405)
0.1 0.4 GO:0007172 signal complex assembly(GO:0007172)
0.1 0.1 GO:0002666 T cell tolerance induction(GO:0002517) regulation of T cell tolerance induction(GO:0002664) positive regulation of T cell tolerance induction(GO:0002666)
0.0 0.1 GO:0045348 positive regulation of MHC class II biosynthetic process(GO:0045348)
0.0 0.1 GO:0002925 positive regulation of humoral immune response mediated by circulating immunoglobulin(GO:0002925)
0.0 0.6 GO:0045086 positive regulation of interleukin-2 biosynthetic process(GO:0045086)
0.0 0.1 GO:0048742 regulation of skeletal muscle fiber development(GO:0048742)
0.0 0.1 GO:0001766 membrane raft polarization(GO:0001766) membrane raft distribution(GO:0031580)
0.0 0.6 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.0 0.1 GO:0002323 natural killer cell activation involved in immune response(GO:0002323) natural killer cell degranulation(GO:0043320)
0.0 0.1 GO:0060523 prostate epithelial cord elongation(GO:0060523)
0.0 0.1 GO:0010572 positive regulation of platelet activation(GO:0010572)
0.0 0.1 GO:0032713 negative regulation of interleukin-4 production(GO:0032713)
0.0 0.2 GO:0031062 positive regulation of histone methylation(GO:0031062)
0.0 0.1 GO:0002282 microglial cell activation involved in immune response(GO:0002282)
0.0 0.2 GO:0033152 immunoglobulin V(D)J recombination(GO:0033152)
0.0 0.3 GO:0006198 cAMP catabolic process(GO:0006198)
0.0 0.1 GO:0048304 positive regulation of isotype switching to IgG isotypes(GO:0048304)
0.0 0.1 GO:0010957 negative regulation of calcidiol 1-monooxygenase activity(GO:0010956) negative regulation of vitamin D biosynthetic process(GO:0010957) negative regulation of vitamin metabolic process(GO:0046137)
0.0 0.3 GO:0030206 chondroitin sulfate biosynthetic process(GO:0030206)
0.0 0.4 GO:0019059 obsolete initiation of viral infection(GO:0019059)
0.0 0.1 GO:0045722 positive regulation of gluconeogenesis(GO:0045722)
0.0 0.0 GO:0033622 integrin activation(GO:0033622)
0.0 0.1 GO:0015917 aminophospholipid transport(GO:0015917)
0.0 0.1 GO:0002313 mature B cell differentiation involved in immune response(GO:0002313)
0.0 0.1 GO:0071072 negative regulation of phospholipid biosynthetic process(GO:0071072)
0.0 0.1 GO:0090116 DNA methylation on cytosine(GO:0032776) C-5 methylation of cytosine(GO:0090116)
0.0 0.4 GO:0000303 response to superoxide(GO:0000303)
0.0 0.1 GO:0006772 thiamine metabolic process(GO:0006772)
0.0 0.1 GO:0043653 mitochondrial fragmentation involved in apoptotic process(GO:0043653)
0.0 0.2 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.0 0.1 GO:0045349 interferon-alpha biosynthetic process(GO:0045349) regulation of interferon-alpha biosynthetic process(GO:0045354) positive regulation of interferon-alpha biosynthetic process(GO:0045356)
0.0 0.1 GO:0030223 neutrophil differentiation(GO:0030223)
0.0 0.0 GO:0045423 regulation of granulocyte macrophage colony-stimulating factor biosynthetic process(GO:0045423)
0.0 0.1 GO:0045056 transcytosis(GO:0045056)
0.0 0.0 GO:0002523 leukocyte migration involved in inflammatory response(GO:0002523)
0.0 0.1 GO:0006678 glucosylceramide metabolic process(GO:0006678)
0.0 0.4 GO:0050853 B cell receptor signaling pathway(GO:0050853)
0.0 0.1 GO:0001672 regulation of chromatin assembly or disassembly(GO:0001672)
0.0 0.1 GO:0003100 regulation of systemic arterial blood pressure by endothelin(GO:0003100)
0.0 0.1 GO:0045657 positive regulation of monocyte differentiation(GO:0045657)
0.0 0.5 GO:0046834 lipid phosphorylation(GO:0046834)
0.0 0.1 GO:0070682 proteasome regulatory particle assembly(GO:0070682)
0.0 0.1 GO:0035455 response to interferon-alpha(GO:0035455)
0.0 0.0 GO:0060397 JAK-STAT cascade involved in growth hormone signaling pathway(GO:0060397)
0.0 0.0 GO:0071801 regulation of podosome assembly(GO:0071801) positive regulation of podosome assembly(GO:0071803)
0.0 0.2 GO:0002714 positive regulation of B cell mediated immunity(GO:0002714) positive regulation of immunoglobulin mediated immune response(GO:0002891)
0.0 0.1 GO:0042989 sequestering of actin monomers(GO:0042989)
0.0 0.1 GO:0003323 type B pancreatic cell development(GO:0003323)
0.0 0.0 GO:0002448 mast cell mediated immunity(GO:0002448)
0.0 0.1 GO:0006975 DNA damage induced protein phosphorylation(GO:0006975)
0.0 0.0 GO:0002887 negative regulation of myeloid leukocyte mediated immunity(GO:0002887) negative regulation of leukocyte degranulation(GO:0043301)
0.0 0.1 GO:0046968 peptide antigen transport(GO:0046968)
0.0 0.0 GO:0006922 obsolete cleavage of lamin involved in execution phase of apoptosis(GO:0006922)
0.0 0.0 GO:0030812 negative regulation of nucleotide catabolic process(GO:0030812)
0.0 0.1 GO:0006089 lactate metabolic process(GO:0006089)
0.0 0.1 GO:0045084 positive regulation of interleukin-12 biosynthetic process(GO:0045084)
0.0 0.1 GO:0015015 heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.0 0.1 GO:0007256 activation of JNKK activity(GO:0007256)
0.0 0.1 GO:0061030 epithelial cell differentiation involved in mammary gland alveolus development(GO:0061030)
0.0 0.2 GO:0006491 N-glycan processing(GO:0006491)
0.0 0.1 GO:1901522 positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus(GO:1901522)
0.0 0.0 GO:0061154 endothelial tube morphogenesis(GO:0061154)
0.0 0.1 GO:0060999 positive regulation of dendritic spine development(GO:0060999)
0.0 0.1 GO:0018076 N-terminal peptidyl-lysine acetylation(GO:0018076)
0.0 0.1 GO:0032747 positive regulation of interleukin-23 production(GO:0032747)
0.0 0.1 GO:0033261 obsolete regulation of S phase(GO:0033261)
0.0 0.1 GO:0032790 ribosome disassembly(GO:0032790)
0.0 0.1 GO:0006556 S-adenosylmethionine biosynthetic process(GO:0006556)
0.0 0.1 GO:0014067 negative regulation of phosphatidylinositol 3-kinase signaling(GO:0014067)
0.0 0.1 GO:0061647 histone H3-K9 methylation(GO:0051567) histone H3-K9 modification(GO:0061647)
0.0 0.0 GO:0006659 phosphatidylserine biosynthetic process(GO:0006659)
0.0 0.3 GO:0045576 mast cell activation(GO:0045576)
0.0 0.1 GO:0032100 positive regulation of response to food(GO:0032097) positive regulation of appetite(GO:0032100)
0.0 0.1 GO:0007095 mitotic G2 DNA damage checkpoint(GO:0007095)
0.0 0.1 GO:0017182 peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183)
0.0 0.1 GO:0002085 inhibition of neuroepithelial cell differentiation(GO:0002085)
0.0 0.1 GO:0003077 obsolete negative regulation of diuresis(GO:0003077)
0.0 0.0 GO:0002328 pro-B cell differentiation(GO:0002328)
0.0 0.1 GO:0002478 antigen processing and presentation of exogenous peptide antigen(GO:0002478)
0.0 0.1 GO:0030540 female genitalia development(GO:0030540)
0.0 0.2 GO:0031648 protein destabilization(GO:0031648)
0.0 0.3 GO:0060330 regulation of response to interferon-gamma(GO:0060330) regulation of interferon-gamma-mediated signaling pathway(GO:0060334)
0.0 0.4 GO:0050868 negative regulation of T cell activation(GO:0050868) negative regulation of leukocyte cell-cell adhesion(GO:1903038)
0.0 0.1 GO:0000042 protein targeting to Golgi(GO:0000042) establishment of protein localization to Golgi(GO:0072600)
0.0 0.1 GO:0048617 embryonic foregut morphogenesis(GO:0048617)
0.0 0.1 GO:0045351 type I interferon biosynthetic process(GO:0045351)
0.0 0.1 GO:0003056 regulation of vascular smooth muscle contraction(GO:0003056)
0.0 0.0 GO:0045978 negative regulation of nucleoside metabolic process(GO:0045978) negative regulation of ATP metabolic process(GO:1903579)
0.0 0.0 GO:0002923 regulation of humoral immune response mediated by circulating immunoglobulin(GO:0002923)
0.0 0.1 GO:0010613 positive regulation of cardiac muscle hypertrophy(GO:0010613) positive regulation of muscle hypertrophy(GO:0014742)
0.0 0.0 GO:0060744 thelarche(GO:0042695) mammary gland branching involved in thelarche(GO:0060744)
0.0 0.2 GO:0043508 negative regulation of JUN kinase activity(GO:0043508)
0.0 0.1 GO:0002921 negative regulation of humoral immune response(GO:0002921)
0.0 0.1 GO:0040023 establishment of nucleus localization(GO:0040023)
0.0 0.1 GO:0043518 negative regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043518) negative regulation of signal transduction by p53 class mediator(GO:1901797)
0.0 0.0 GO:0070602 centromeric sister chromatid cohesion(GO:0070601) regulation of centromeric sister chromatid cohesion(GO:0070602)
0.0 0.1 GO:0006167 AMP biosynthetic process(GO:0006167)
0.0 0.1 GO:0050860 negative regulation of antigen receptor-mediated signaling pathway(GO:0050858) negative regulation of T cell receptor signaling pathway(GO:0050860)
0.0 0.1 GO:0008653 lipopolysaccharide metabolic process(GO:0008653)
0.0 0.1 GO:0048715 negative regulation of oligodendrocyte differentiation(GO:0048715)
0.0 0.1 GO:0001661 conditioned taste aversion(GO:0001661)
0.0 0.1 GO:0048496 maintenance of organ identity(GO:0048496)
0.0 0.0 GO:0072182 nephron tubule epithelial cell differentiation(GO:0072160) regulation of nephron tubule epithelial cell differentiation(GO:0072182) regulation of epithelial cell differentiation involved in kidney development(GO:2000696)
0.0 0.1 GO:0009301 snRNA transcription(GO:0009301)
0.0 0.1 GO:0070570 regulation of axon regeneration(GO:0048679) regulation of neuron projection regeneration(GO:0070570)
0.0 0.1 GO:0010624 regulation of Schwann cell proliferation(GO:0010624) negative regulation of Schwann cell proliferation(GO:0010626)
0.0 0.0 GO:0010587 miRNA metabolic process(GO:0010586) miRNA catabolic process(GO:0010587)
0.0 0.4 GO:0050690 regulation of defense response to virus by virus(GO:0050690)
0.0 0.1 GO:0051044 positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
0.0 0.0 GO:0070102 interleukin-6-mediated signaling pathway(GO:0070102)
0.0 0.0 GO:0006007 glucose catabolic process(GO:0006007)
0.0 0.1 GO:0010759 positive regulation of macrophage chemotaxis(GO:0010759)
0.0 0.0 GO:0042670 retinal cone cell differentiation(GO:0042670) retinal cone cell development(GO:0046549)
0.0 0.1 GO:0007158 neuron cell-cell adhesion(GO:0007158)
0.0 0.2 GO:0031146 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process(GO:0031146)
0.0 0.0 GO:0021571 rhombomere 5 development(GO:0021571)
0.0 0.1 GO:0006474 N-terminal protein amino acid acetylation(GO:0006474)
0.0 0.1 GO:0010508 positive regulation of autophagy(GO:0010508)
0.0 0.0 GO:0002495 antigen processing and presentation of peptide antigen via MHC class II(GO:0002495)
0.0 0.0 GO:0070672 response to interleukin-15(GO:0070672)
0.0 0.0 GO:0070933 histone H3 deacetylation(GO:0070932) histone H4 deacetylation(GO:0070933)
0.0 0.1 GO:0000089 mitotic metaphase(GO:0000089)
0.0 0.0 GO:0045842 positive regulation of mitotic metaphase/anaphase transition(GO:0045842) positive regulation of mitotic sister chromatid separation(GO:1901970) positive regulation of metaphase/anaphase transition of cell cycle(GO:1902101)
0.0 0.1 GO:0071108 protein K48-linked deubiquitination(GO:0071108)
0.0 0.1 GO:0005513 detection of calcium ion(GO:0005513)
0.0 0.0 GO:0033632 regulation of cell-cell adhesion mediated by integrin(GO:0033632)
0.0 0.0 GO:0002320 lymphoid progenitor cell differentiation(GO:0002320)
0.0 0.0 GO:0031060 regulation of histone methylation(GO:0031060)
0.0 0.1 GO:0006689 ganglioside catabolic process(GO:0006689)
0.0 0.1 GO:0007023 post-chaperonin tubulin folding pathway(GO:0007023)
0.0 0.1 GO:0034755 iron ion transmembrane transport(GO:0034755)
0.0 0.0 GO:0097300 necroptotic process(GO:0070266) programmed necrotic cell death(GO:0097300)
0.0 0.0 GO:0007191 adenylate cyclase-activating dopamine receptor signaling pathway(GO:0007191)
0.0 0.2 GO:0016925 protein sumoylation(GO:0016925)
0.0 0.1 GO:0015937 coenzyme A biosynthetic process(GO:0015937)
0.0 0.2 GO:0032012 regulation of ARF protein signal transduction(GO:0032012)
0.0 0.1 GO:0045824 negative regulation of innate immune response(GO:0045824)
0.0 0.1 GO:0008628 hormone-mediated apoptotic signaling pathway(GO:0008628)
0.0 0.2 GO:0042776 mitochondrial ATP synthesis coupled proton transport(GO:0042776)
0.0 0.0 GO:0060219 camera-type eye photoreceptor cell differentiation(GO:0060219)
0.0 0.1 GO:0016572 histone phosphorylation(GO:0016572)
0.0 0.1 GO:0060263 regulation of respiratory burst(GO:0060263)
0.0 0.1 GO:0072531 pyrimidine-containing compound transmembrane transport(GO:0072531)
0.0 0.0 GO:0051024 positive regulation of immunoglobulin secretion(GO:0051024)
0.0 0.0 GO:1903077 negative regulation of establishment of protein localization to plasma membrane(GO:0090005) negative regulation of protein localization to plasma membrane(GO:1903077) negative regulation of protein localization to cell periphery(GO:1904376)
0.0 0.1 GO:0045730 respiratory burst(GO:0045730)
0.0 0.0 GO:0042362 fat-soluble vitamin biosynthetic process(GO:0042362)
0.0 0.0 GO:0032506 cytokinetic process(GO:0032506)
0.0 0.1 GO:0045059 positive thymic T cell selection(GO:0045059)
0.0 0.0 GO:0098754 detoxification(GO:0098754)
0.0 0.1 GO:0090205 positive regulation of cholesterol metabolic process(GO:0090205)
0.0 0.1 GO:0060017 parathyroid gland development(GO:0060017)
0.0 0.0 GO:0001831 trophectodermal cellular morphogenesis(GO:0001831)
0.0 0.0 GO:0007000 nucleolus organization(GO:0007000)
0.0 0.0 GO:0043951 negative regulation of cAMP-mediated signaling(GO:0043951)
0.0 0.1 GO:0007168 receptor guanylyl cyclase signaling pathway(GO:0007168)
0.0 0.1 GO:0000730 DNA recombinase assembly(GO:0000730) double-strand break repair via synthesis-dependent strand annealing(GO:0045003)
0.0 0.0 GO:0003402 planar cell polarity pathway involved in axis elongation(GO:0003402)
0.0 0.0 GO:0006154 adenosine catabolic process(GO:0006154)
0.0 0.0 GO:0048291 isotype switching to IgG isotypes(GO:0048291)
0.0 0.0 GO:0034626 fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.0 0.1 GO:0021561 facial nerve development(GO:0021561)
0.0 0.0 GO:0006610 ribosomal protein import into nucleus(GO:0006610)
0.0 0.1 GO:0015671 oxygen transport(GO:0015671)
0.0 0.1 GO:0006269 DNA replication, synthesis of RNA primer(GO:0006269)
0.0 0.1 GO:0016265 obsolete death(GO:0016265)
0.0 0.0 GO:0043383 negative T cell selection(GO:0043383)
0.0 0.1 GO:0033169 histone H3-K9 demethylation(GO:0033169)
0.0 0.1 GO:0051085 chaperone mediated protein folding requiring cofactor(GO:0051085)
0.0 0.0 GO:0034244 negative regulation of DNA-templated transcription, elongation(GO:0032785) negative regulation of transcription elongation from RNA polymerase II promoter(GO:0034244)
0.0 0.1 GO:0000270 peptidoglycan metabolic process(GO:0000270) peptidoglycan catabolic process(GO:0009253)
0.0 0.1 GO:0035020 regulation of Rac protein signal transduction(GO:0035020)
0.0 0.0 GO:0050849 negative regulation of calcium-mediated signaling(GO:0050849)
0.0 0.0 GO:0042535 positive regulation of tumor necrosis factor biosynthetic process(GO:0042535)
0.0 0.1 GO:0008595 tripartite regional subdivision(GO:0007351) anterior/posterior axis specification, embryo(GO:0008595)
0.0 0.1 GO:0006685 sphingomyelin catabolic process(GO:0006685)
0.0 0.0 GO:0060586 multicellular organismal iron ion homeostasis(GO:0060586)
0.0 0.0 GO:0040016 embryonic cleavage(GO:0040016)
0.0 0.0 GO:0002369 T cell cytokine production(GO:0002369) positive regulation of T cell cytokine production(GO:0002726)
0.0 0.2 GO:0051923 sulfation(GO:0051923)
0.0 0.1 GO:0007035 vacuolar acidification(GO:0007035)
0.0 0.1 GO:0006528 asparagine metabolic process(GO:0006528)
0.0 0.0 GO:0006432 phenylalanyl-tRNA aminoacylation(GO:0006432)
0.0 0.0 GO:0045002 DNA double-strand break processing involved in repair via single-strand annealing(GO:0010792) double-strand break repair via single-strand annealing(GO:0045002)
0.0 0.0 GO:0006422 aspartyl-tRNA aminoacylation(GO:0006422)
0.0 0.0 GO:0032875 regulation of DNA endoreduplication(GO:0032875) negative regulation of DNA endoreduplication(GO:0032876) DNA endoreduplication(GO:0042023)
0.0 0.1 GO:0051290 protein heterotetramerization(GO:0051290)
0.0 0.1 GO:1901072 amino sugar catabolic process(GO:0046348) glucosamine-containing compound catabolic process(GO:1901072)
0.0 0.0 GO:0070837 dehydroascorbic acid transport(GO:0070837)
0.0 0.0 GO:0001992 regulation of systemic arterial blood pressure by vasopressin(GO:0001992)
0.0 0.1 GO:0006111 regulation of gluconeogenesis(GO:0006111)
0.0 0.1 GO:0046329 negative regulation of JNK cascade(GO:0046329)
0.0 0.0 GO:0048711 positive regulation of astrocyte differentiation(GO:0048711)
0.0 0.0 GO:0010980 regulation of vitamin D 24-hydroxylase activity(GO:0010979) positive regulation of vitamin D 24-hydroxylase activity(GO:0010980)
0.0 0.0 GO:0090201 negative regulation of mitochondrion organization(GO:0010823) negative regulation of release of cytochrome c from mitochondria(GO:0090201) negative regulation of apoptotic signaling pathway(GO:2001234)
0.0 0.0 GO:0045875 negative regulation of sister chromatid cohesion(GO:0045875)
0.0 0.0 GO:2000192 negative regulation of plasma membrane long-chain fatty acid transport(GO:0010748) negative regulation of anion transmembrane transport(GO:1903960) negative regulation of fatty acid transport(GO:2000192)
0.0 0.0 GO:0051970 negative regulation of transmission of nerve impulse(GO:0051970)
0.0 0.0 GO:0006855 drug transmembrane transport(GO:0006855)
0.0 0.1 GO:0070493 thrombin receptor signaling pathway(GO:0070493)
0.0 0.0 GO:0009221 pyrimidine deoxyribonucleotide biosynthetic process(GO:0009221)
0.0 0.0 GO:0007100 mitotic centrosome separation(GO:0007100)
0.0 0.0 GO:0045343 MHC class I biosynthetic process(GO:0045341) regulation of MHC class I biosynthetic process(GO:0045343)
0.0 0.0 GO:0007343 egg activation(GO:0007343)
0.0 0.0 GO:0021615 glossopharyngeal nerve development(GO:0021563) glossopharyngeal nerve morphogenesis(GO:0021615)
0.0 0.0 GO:0031936 negative regulation of chromatin silencing(GO:0031936)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0001891 phagocytic cup(GO:0001891)
0.0 0.1 GO:0000306 extrinsic component of vacuolar membrane(GO:0000306) extrinsic component of endosome membrane(GO:0031313)
0.0 0.1 GO:0001940 male pronucleus(GO:0001940)
0.0 0.1 GO:0070022 transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.0 0.2 GO:0070775 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.0 0.1 GO:0005826 actomyosin contractile ring(GO:0005826)
0.0 0.1 GO:0032009 early phagosome(GO:0032009)
0.0 0.1 GO:0008540 proteasome regulatory particle, base subcomplex(GO:0008540)
0.0 0.2 GO:0031527 filopodium membrane(GO:0031527)
0.0 0.1 GO:0031088 platelet dense granule membrane(GO:0031088)
0.0 0.3 GO:0042101 T cell receptor complex(GO:0042101)
0.0 0.3 GO:0001772 immunological synapse(GO:0001772)
0.0 0.1 GO:0032444 activin responsive factor complex(GO:0032444)
0.0 0.1 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.0 0.1 GO:0043218 compact myelin(GO:0043218)
0.0 0.2 GO:0016585 obsolete chromatin remodeling complex(GO:0016585)
0.0 0.1 GO:0034045 pre-autophagosomal structure membrane(GO:0034045)
0.0 0.3 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.0 0.3 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.0 0.1 GO:0000275 mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275)
0.0 0.1 GO:0033011 perinuclear theca(GO:0033011)
0.0 0.1 GO:0005658 alpha DNA polymerase:primase complex(GO:0005658)
0.0 0.1 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.0 0.1 GO:0005954 calcium- and calmodulin-dependent protein kinase complex(GO:0005954)
0.0 0.1 GO:0042583 chromaffin granule(GO:0042583) chromaffin granule membrane(GO:0042584)
0.0 0.2 GO:0042597 outer membrane-bounded periplasmic space(GO:0030288) periplasmic space(GO:0042597)
0.0 0.2 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.0 0.1 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
0.0 0.0 GO:0002142 stereocilia coupling link(GO:0002139) stereocilia ankle link(GO:0002141) stereocilia ankle link complex(GO:0002142)
0.0 0.0 GO:0005896 interleukin-6 receptor complex(GO:0005896)
0.0 0.0 GO:0031205 endoplasmic reticulum Sec complex(GO:0031205)
0.0 0.1 GO:0072357 PTW/PP1 phosphatase complex(GO:0072357)
0.0 0.1 GO:0000791 euchromatin(GO:0000791)
0.0 0.0 GO:0072487 MSL complex(GO:0072487)
0.0 0.0 GO:0071438 invadopodium membrane(GO:0071438)
0.0 0.0 GO:0000942 condensed nuclear chromosome outer kinetochore(GO:0000942)
0.0 0.0 GO:0001652 granular component(GO:0001652)
0.0 0.1 GO:0097526 U4/U6 x U5 tri-snRNP complex(GO:0046540) spliceosomal tri-snRNP complex(GO:0097526)
0.0 0.1 GO:0090533 cation-transporting ATPase complex(GO:0090533)
0.0 0.0 GO:0044462 external encapsulating structure part(GO:0044462)
0.0 0.1 GO:0019773 proteasome core complex, alpha-subunit complex(GO:0019773)
0.0 0.1 GO:0071778 obsolete WINAC complex(GO:0071778)
0.0 0.1 GO:0000153 cytoplasmic ubiquitin ligase complex(GO:0000153)
0.0 0.1 GO:0043209 myelin sheath(GO:0043209)
0.0 0.0 GO:0030008 TRAPP complex(GO:0030008)
0.0 0.0 GO:0016939 kinesin II complex(GO:0016939)
0.0 0.2 GO:0034362 low-density lipoprotein particle(GO:0034362)
0.0 0.1 GO:0031264 death-inducing signaling complex(GO:0031264)
0.0 0.1 GO:0035189 Rb-E2F complex(GO:0035189)
0.0 0.1 GO:0043190 ATP-binding cassette (ABC) transporter complex(GO:0043190)
0.0 0.1 GO:0031083 BLOC complex(GO:0031082) BLOC-1 complex(GO:0031083)
0.0 0.1 GO:0045120 pronucleus(GO:0045120)
0.0 0.1 GO:0032590 dendrite membrane(GO:0032590)
0.0 0.0 GO:0070552 BRISC complex(GO:0070552)
0.0 0.0 GO:0005672 transcription factor TFIIA complex(GO:0005672)
0.0 0.1 GO:0005869 dynactin complex(GO:0005869)
0.0 0.1 GO:0071564 npBAF complex(GO:0071564)
0.0 0.1 GO:0061202 clathrin-sculpted gamma-aminobutyric acid transport vesicle(GO:0061200) clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane(GO:0061202)
0.0 0.1 GO:0030130 clathrin coat of trans-Golgi network vesicle(GO:0030130)
0.0 0.1 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.0 0.3 GO:0005626 obsolete insoluble fraction(GO:0005626)
0.0 0.0 GO:0070688 MLL5-L complex(GO:0070688)
0.0 0.2 GO:0005776 autophagosome(GO:0005776)
0.0 0.1 GO:0000145 exocyst(GO:0000145)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0016309 1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
0.1 0.3 GO:0052813 phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) phosphatidylinositol bisphosphate kinase activity(GO:0052813)
0.1 0.2 GO:0035184 histone threonine kinase activity(GO:0035184)
0.1 0.2 GO:0003836 beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.1 0.5 GO:0016493 C-C chemokine receptor activity(GO:0016493)
0.0 0.2 GO:0047238 glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity(GO:0047238)
0.0 0.1 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
0.0 0.1 GO:0047894 flavonol 3-sulfotransferase activity(GO:0047894)
0.0 0.3 GO:0016494 C-X-C chemokine receptor activity(GO:0016494)
0.0 0.1 GO:0047756 chondroitin 4-sulfotransferase activity(GO:0047756)
0.0 0.1 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.0 0.1 GO:0004911 interleukin-2 receptor activity(GO:0004911)
0.0 0.1 GO:0033691 sialic acid binding(GO:0033691)
0.0 0.2 GO:0030284 estrogen receptor activity(GO:0030284)
0.0 0.1 GO:0030375 thyroid hormone receptor coactivator activity(GO:0030375)
0.0 0.9 GO:0045028 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.0 0.4 GO:0004697 protein kinase C activity(GO:0004697)
0.0 0.1 GO:0051734 ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity(GO:0046404) polydeoxyribonucleotide kinase activity(GO:0051733) ATP-dependent polynucleotide kinase activity(GO:0051734)
0.0 0.1 GO:0016314 phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity(GO:0016314)
0.0 0.1 GO:0015252 hydrogen ion channel activity(GO:0015252)
0.0 0.1 GO:0004904 interferon receptor activity(GO:0004904)
0.0 0.1 GO:0015925 galactosidase activity(GO:0015925)
0.0 0.1 GO:0047631 ADP-ribose diphosphatase activity(GO:0047631)
0.0 0.1 GO:0031705 bombesin receptor binding(GO:0031705) endothelin B receptor binding(GO:0031708)
0.0 0.2 GO:0034593 phosphatidylinositol bisphosphate phosphatase activity(GO:0034593)
0.0 0.1 GO:0035197 siRNA binding(GO:0035197)
0.0 0.1 GO:0004465 lipoprotein lipase activity(GO:0004465)
0.0 0.1 GO:0016004 phospholipase activator activity(GO:0016004)
0.0 0.1 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.0 0.1 GO:0046974 histone methyltransferase activity (H3-K9 specific)(GO:0046974)
0.0 0.1 GO:0016842 amidine-lyase activity(GO:0016842)
0.0 0.2 GO:0001784 phosphotyrosine binding(GO:0001784)
0.0 0.1 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.0 0.1 GO:0003987 acetate-CoA ligase activity(GO:0003987)
0.0 0.1 GO:0004974 leukotriene receptor activity(GO:0004974)
0.0 0.1 GO:0004950 G-protein coupled chemoattractant receptor activity(GO:0001637) chemokine receptor activity(GO:0004950)
0.0 0.1 GO:0070053 thrombospondin receptor activity(GO:0070053)
0.0 0.2 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.0 0.1 GO:0008545 JUN kinase kinase activity(GO:0008545)
0.0 0.1 GO:0008745 N-acetylmuramoyl-L-alanine amidase activity(GO:0008745)
0.0 1.2 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.0 0.5 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.0 0.2 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.0 0.1 GO:0004949 cannabinoid receptor activity(GO:0004949)
0.0 0.1 GO:0005131 growth hormone receptor binding(GO:0005131)
0.0 0.1 GO:0042834 peptidoglycan binding(GO:0042834)
0.0 0.1 GO:0004351 glutamate decarboxylase activity(GO:0004351)
0.0 0.1 GO:0004449 isocitrate dehydrogenase (NAD+) activity(GO:0004449)
0.0 0.1 GO:0030368 interleukin-17 receptor activity(GO:0030368)
0.0 0.1 GO:0043141 ATP-dependent 5'-3' DNA helicase activity(GO:0043141)
0.0 0.8 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.0 0.1 GO:0031957 very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.0 0.1 GO:0004525 ribonuclease III activity(GO:0004525) double-stranded RNA-specific ribonuclease activity(GO:0032296)
0.0 0.1 GO:0004476 mannose-6-phosphate isomerase activity(GO:0004476)
0.0 0.3 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0 0.1 GO:0008321 Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.0 0.0 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.0 0.0 GO:0019959 C-X-C chemokine binding(GO:0019958) interleukin-8 binding(GO:0019959)
0.0 0.1 GO:0051400 BH domain binding(GO:0051400)
0.0 0.1 GO:0004176 ATP-dependent peptidase activity(GO:0004176)
0.0 0.3 GO:0019198 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.0 0.1 GO:0003953 NAD+ nucleosidase activity(GO:0003953)
0.0 0.1 GO:0004957 prostaglandin E receptor activity(GO:0004957)
0.0 0.1 GO:0004969 histamine receptor activity(GO:0004969)
0.0 0.1 GO:0008109 N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109)
0.0 0.1 GO:0005132 type I interferon receptor binding(GO:0005132)
0.0 0.1 GO:0050700 CARD domain binding(GO:0050700)
0.0 0.1 GO:0008159 obsolete positive transcription elongation factor activity(GO:0008159)
0.0 0.1 GO:0005381 iron ion transmembrane transporter activity(GO:0005381)
0.0 0.0 GO:0045118 azole transporter activity(GO:0045118) azole transmembrane transporter activity(GO:1901474)
0.0 0.1 GO:0050321 tau-protein kinase activity(GO:0050321)
0.0 0.1 GO:0031628 opioid receptor binding(GO:0031628)
0.0 0.1 GO:1990939 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574) ATP-dependent microtubule motor activity(GO:1990939)
0.0 0.1 GO:0030955 potassium ion binding(GO:0030955)
0.0 0.2 GO:0017025 TBP-class protein binding(GO:0017025)
0.0 0.1 GO:0004802 transketolase activity(GO:0004802)
0.0 0.2 GO:0032452 histone demethylase activity(GO:0032452)
0.0 0.1 GO:0031701 angiotensin receptor binding(GO:0031701)
0.0 0.1 GO:0004719 protein-L-isoaspartate (D-aspartate) O-methyltransferase activity(GO:0004719)
0.0 0.1 GO:0016748 succinyltransferase activity(GO:0016748)
0.0 0.1 GO:0016520 growth hormone-releasing hormone receptor activity(GO:0016520)
0.0 0.1 GO:0005522 profilin binding(GO:0005522)
0.0 0.1 GO:0004046 aminoacylase activity(GO:0004046)
0.0 0.1 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.0 0.1 GO:0008518 reduced folate carrier activity(GO:0008518)
0.0 0.0 GO:0005275 amine transmembrane transporter activity(GO:0005275)
0.0 0.0 GO:0043398 HLH domain binding(GO:0043398)
0.0 0.1 GO:0004340 glucokinase activity(GO:0004340)
0.0 0.0 GO:0005113 patched binding(GO:0005113)
0.0 0.4 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435)
0.0 0.0 GO:0042799 histone methyltransferase activity (H4-K20 specific)(GO:0042799)
0.0 0.1 GO:0015355 secondary active monocarboxylate transmembrane transporter activity(GO:0015355)
0.0 0.0 GO:0016361 activin receptor activity, type I(GO:0016361)
0.0 0.2 GO:0005095 GTPase inhibitor activity(GO:0005095)
0.0 0.0 GO:0071208 histone pre-mRNA DCP binding(GO:0071208)
0.0 0.0 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.0 0.1 GO:0005338 nucleotide-sugar transmembrane transporter activity(GO:0005338)
0.0 0.1 GO:0001727 lipid kinase activity(GO:0001727)
0.0 0.1 GO:0035252 UDP-xylosyltransferase activity(GO:0035252) xylosyltransferase activity(GO:0042285)
0.0 0.1 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.0 0.0 GO:0003909 DNA ligase activity(GO:0003909) DNA ligase (ATP) activity(GO:0003910)
0.0 0.1 GO:0004028 3-chloroallyl aldehyde dehydrogenase activity(GO:0004028)
0.0 0.0 GO:0004370 glycerol kinase activity(GO:0004370)
0.0 0.1 GO:0004704 NF-kappaB-inducing kinase activity(GO:0004704)
0.0 0.1 GO:0019136 deoxynucleoside kinase activity(GO:0019136)
0.0 0.0 GO:0005176 ErbB-2 class receptor binding(GO:0005176)
0.0 0.1 GO:0001671 ATPase activator activity(GO:0001671)
0.0 0.1 GO:0005000 vasopressin receptor activity(GO:0005000)
0.0 0.1 GO:0004826 phenylalanine-tRNA ligase activity(GO:0004826)
0.0 0.2 GO:0043621 protein self-association(GO:0043621)
0.0 0.1 GO:0004457 lactate dehydrogenase activity(GO:0004457)
0.0 0.1 GO:0004908 interleukin-1 receptor activity(GO:0004908)
0.0 0.1 GO:0043024 ribosomal small subunit binding(GO:0043024)
0.0 0.1 GO:0008266 poly(U) RNA binding(GO:0008266)
0.0 0.0 GO:0004311 farnesyltranstransferase activity(GO:0004311)
0.0 0.1 GO:0051766 inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440) inositol trisphosphate kinase activity(GO:0051766)
0.0 0.1 GO:0019864 IgG binding(GO:0019864)
0.0 0.1 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.0 0.1 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.0 0.0 GO:0000064 L-ornithine transmembrane transporter activity(GO:0000064)
0.0 0.0 GO:0048156 tau protein binding(GO:0048156)
0.0 0.2 GO:0030159 receptor signaling complex scaffold activity(GO:0030159)
0.0 0.1 GO:0043425 bHLH transcription factor binding(GO:0043425)
0.0 0.1 GO:0050431 transforming growth factor beta binding(GO:0050431)
0.0 0.1 GO:0030169 low-density lipoprotein particle binding(GO:0030169)
0.0 0.1 GO:0003785 actin monomer binding(GO:0003785)
0.0 0.2 GO:0001540 beta-amyloid binding(GO:0001540)
0.0 0.2 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.0 0.0 GO:0016972 thiol oxidase activity(GO:0016972)
0.0 0.1 GO:0031593 polyubiquitin binding(GO:0031593)
0.0 0.1 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.0 0.1 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.0 0.0 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.0 0.3 GO:0003725 double-stranded RNA binding(GO:0003725)
0.0 0.0 GO:0001609 G-protein coupled adenosine receptor activity(GO:0001609)
0.0 0.0 GO:0051425 PTB domain binding(GO:0051425)
0.0 0.0 GO:0015562 efflux transmembrane transporter activity(GO:0015562)
0.0 0.0 GO:0033300 dehydroascorbic acid transporter activity(GO:0033300)
0.0 0.2 GO:0043499 obsolete eukaryotic cell surface binding(GO:0043499)
0.0 0.1 GO:0015924 mannosyl-oligosaccharide mannosidase activity(GO:0015924)
0.0 0.1 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624) ubiquitin-like protein conjugating enzyme binding(GO:0044390)
0.0 0.0 GO:0015057 thrombin receptor activity(GO:0015057)
0.0 0.0 GO:0003918 DNA topoisomerase type II (ATP-hydrolyzing) activity(GO:0003918) DNA topoisomerase II activity(GO:0061505)
0.0 0.0 GO:0015226 amino-acid betaine transmembrane transporter activity(GO:0015199) carnitine transmembrane transporter activity(GO:0015226)
0.0 0.2 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.0 0.1 GO:0005031 tumor necrosis factor-activated receptor activity(GO:0005031)
0.0 0.1 GO:0004383 guanylate cyclase activity(GO:0004383)
0.0 0.0 GO:0004591 oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591)
0.0 0.0 GO:0008821 crossover junction endodeoxyribonuclease activity(GO:0008821)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 3.0 PID TCR PATHWAY TCR signaling in naïve CD4+ T cells
0.0 0.4 SA PTEN PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.0 0.3 ST JAK STAT PATHWAY Jak-STAT Pathway
0.0 0.0 PID PI3KCI AKT PATHWAY Class I PI3K signaling events mediated by Akt
0.0 0.3 PID IL5 PATHWAY IL5-mediated signaling events
0.0 0.2 ST TYPE I INTERFERON PATHWAY Type I Interferon (alpha/beta IFN) Pathway
0.0 0.8 PID PI3KCI PATHWAY Class I PI3K signaling events
0.0 0.4 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0 0.4 PID EPHRINB REV PATHWAY Ephrin B reverse signaling
0.0 0.3 PID CD40 PATHWAY CD40/CD40L signaling
0.0 0.6 PID BCR 5PATHWAY BCR signaling pathway
0.0 0.1 PID TCR RAS PATHWAY Ras signaling in the CD4+ TCR pathway
0.0 0.2 PID TCR JNK PATHWAY JNK signaling in the CD4+ TCR pathway
0.0 0.2 PID IL2 1PATHWAY IL2-mediated signaling events
0.0 0.2 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
0.0 0.4 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4
0.0 0.3 PID IL2 STAT5 PATHWAY IL2 signaling events mediated by STAT5
0.0 0.4 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.0 0.1 ST GA12 PATHWAY G alpha 12 Pathway
0.0 0.1 PID NFKAPPAB ATYPICAL PATHWAY Atypical NF-kappaB pathway
0.0 0.5 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.0 0.1 PID CD8 TCR PATHWAY TCR signaling in naïve CD8+ T cells
0.0 0.1 PID RANBP2 PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.0 0.1 PID NFKAPPAB CANONICAL PATHWAY Canonical NF-kappaB pathway
0.0 0.8 PID AR TF PATHWAY Regulation of Androgen receptor activity
0.0 0.1 ST PAC1 RECEPTOR PATHWAY PAC1 Receptor Pathway
0.0 0.3 PID IL12 2PATHWAY IL12-mediated signaling events
0.0 0.4 PID TXA2PATHWAY Thromboxane A2 receptor signaling
0.0 0.2 PID FAS PATHWAY FAS (CD95) signaling pathway
0.0 0.3 PID ERBB1 INTERNALIZATION PATHWAY Internalization of ErbB1
0.0 0.6 PID IL4 2PATHWAY IL4-mediated signaling events
0.0 0.3 PID CD8 TCR DOWNSTREAM PATHWAY Downstream signaling in naïve CD8+ T cells
0.0 0.0 PID PDGFRA PATHWAY PDGFR-alpha signaling pathway
0.0 0.0 ST GRANULE CELL SURVIVAL PATHWAY Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway.
0.0 0.0 ST TUMOR NECROSIS FACTOR PATHWAY Tumor Necrosis Factor Pathway.
0.0 0.0 PID CXCR3 PATHWAY CXCR3-mediated signaling events
0.0 0.1 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.0 0.3 PID INSULIN PATHWAY Insulin Pathway
0.0 0.0 PID LPA4 PATHWAY LPA4-mediated signaling events
0.0 0.1 PID INTEGRIN3 PATHWAY Beta3 integrin cell surface interactions
0.0 0.1 PID IL8 CXCR2 PATHWAY IL8- and CXCR2-mediated signaling events
0.0 0.2 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 REACTOME BINDING AND ENTRY OF HIV VIRION Genes involved in Binding and entry of HIV virion
0.1 0.7 REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.1 0.7 REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.1 0.1 REACTOME GPVI MEDIATED ACTIVATION CASCADE Genes involved in GPVI-mediated activation cascade
0.1 0.2 REACTOME G ALPHA Z SIGNALLING EVENTS Genes involved in G alpha (z) signalling events
0.0 1.3 REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.0 0.0 REACTOME G ALPHA1213 SIGNALLING EVENTS Genes involved in G alpha (12/13) signalling events
0.0 0.2 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.0 0.8 REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE Genes involved in Synthesis of PIPs at the plasma membrane
0.0 0.5 REACTOME DOWNSTREAM TCR SIGNALING Genes involved in Downstream TCR signaling
0.0 0.3 REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION Genes involved in activated TAK1 mediates p38 MAPK activation
0.0 0.1 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
0.0 0.0 REACTOME PROSTACYCLIN SIGNALLING THROUGH PROSTACYCLIN RECEPTOR Genes involved in Prostacyclin signalling through prostacyclin receptor
0.0 0.0 REACTOME ADENYLATE CYCLASE INHIBITORY PATHWAY Genes involved in Adenylate cyclase inhibitory pathway
0.0 0.3 REACTOME P2Y RECEPTORS Genes involved in P2Y receptors
0.0 0.1 REACTOME IRAK1 RECRUITS IKK COMPLEX Genes involved in IRAK1 recruits IKK complex
0.0 0.2 REACTOME REGULATION OF IFNG SIGNALING Genes involved in Regulation of IFNG signaling
0.0 0.0 REACTOME G PROTEIN ACTIVATION Genes involved in G-protein activation
0.0 0.1 REACTOME SPRY REGULATION OF FGF SIGNALING Genes involved in Spry regulation of FGF signaling
0.0 0.2 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION Genes involved in TRAF6 mediated IRF7 activation
0.0 0.2 REACTOME NEPHRIN INTERACTIONS Genes involved in Nephrin interactions
0.0 0.3 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.0 0.1 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.0 0.2 REACTOME NFKB ACTIVATION THROUGH FADD RIP1 PATHWAY MEDIATED BY CASPASE 8 AND10 Genes involved in NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10
0.0 0.3 REACTOME REGULATION OF IFNA SIGNALING Genes involved in Regulation of IFNA signaling
0.0 0.2 REACTOME REGULATION OF AMPK ACTIVITY VIA LKB1 Genes involved in Regulation of AMPK activity via LKB1
0.0 0.2 REACTOME IL RECEPTOR SHC SIGNALING Genes involved in Interleukin receptor SHC signaling
0.0 0.0 REACTOME TRAF3 DEPENDENT IRF ACTIVATION PATHWAY Genes involved in TRAF3-dependent IRF activation pathway
0.0 0.4 REACTOME THE ROLE OF NEF IN HIV1 REPLICATION AND DISEASE PATHOGENESIS Genes involved in The role of Nef in HIV-1 replication and disease pathogenesis
0.0 0.3 REACTOME CTLA4 INHIBITORY SIGNALING Genes involved in CTLA4 inhibitory signaling
0.0 0.1 REACTOME REGULATION OF SIGNALING BY CBL Genes involved in Regulation of signaling by CBL
0.0 0.2 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
0.0 0.1 REACTOME PLATELET SENSITIZATION BY LDL Genes involved in Platelet sensitization by LDL
0.0 0.1 REACTOME P38MAPK EVENTS Genes involved in p38MAPK events
0.0 0.2 REACTOME EICOSANOID LIGAND BINDING RECEPTORS Genes involved in Eicosanoid ligand-binding receptors
0.0 0.2 REACTOME GENERATION OF SECOND MESSENGER MOLECULES Genes involved in Generation of second messenger molecules
0.0 0.3 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.0 0.1 REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS Genes involved in Trafficking of GluR2-containing AMPA receptors
0.0 0.1 REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR Genes involved in Trafficking and processing of endosomal TLR
0.0 0.0 REACTOME INHIBITION OF REPLICATION INITIATION OF DAMAGED DNA BY RB1 E2F1 Genes involved in Inhibition of replication initiation of damaged DNA by RB1/E2F1
0.0 0.1 REACTOME NOD1 2 SIGNALING PATHWAY Genes involved in NOD1/2 Signaling Pathway
0.0 0.2 REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING Genes involved in Formation of ATP by chemiosmotic coupling
0.0 0.7 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0 0.2 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.0 0.2 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.0 0.3 REACTOME CHONDROITIN SULFATE BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
0.0 0.1 REACTOME DSCAM INTERACTIONS Genes involved in DSCAM interactions
0.0 0.2 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.0 0.2 REACTOME INFLAMMASOMES Genes involved in Inflammasomes
0.0 0.1 REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.0 0.2 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.0 0.0 REACTOME ENDOSOMAL VACUOLAR PATHWAY Genes involved in Endosomal/Vacuolar pathway
0.0 0.2 REACTOME COSTIMULATION BY THE CD28 FAMILY Genes involved in Costimulation by the CD28 family
0.0 0.1 REACTOME CDC6 ASSOCIATION WITH THE ORC ORIGIN COMPLEX Genes involved in CDC6 association with the ORC:origin complex
0.0 0.1 REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY Genes involved in Regulation of the Fanconi anemia pathway
0.0 0.2 REACTOME G BETA GAMMA SIGNALLING THROUGH PLC BETA Genes involved in G beta:gamma signalling through PLC beta
0.0 0.0 REACTOME NUCLEOTIDE LIKE PURINERGIC RECEPTORS Genes involved in Nucleotide-like (purinergic) receptors
0.0 0.0 REACTOME ASSOCIATION OF LICENSING FACTORS WITH THE PRE REPLICATIVE COMPLEX Genes involved in Association of licensing factors with the pre-replicative complex
0.0 0.0 REACTOME SIGNALING BY ERBB2 Genes involved in Signaling by ERBB2
0.0 0.1 REACTOME SHC RELATED EVENTS Genes involved in SHC-related events
0.0 0.3 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.0 0.1 REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.0 0.1 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.0 0.0 REACTOME PEPTIDE CHAIN ELONGATION Genes involved in Peptide chain elongation
0.0 0.1 REACTOME RAS ACTIVATION UOPN CA2 INFUX THROUGH NMDA RECEPTOR Genes involved in Ras activation uopn Ca2+ infux through NMDA receptor
0.0 0.0 REACTOME ACTIVATION OF NF KAPPAB IN B CELLS Genes involved in Activation of NF-kappaB in B Cells
0.0 0.3 REACTOME INTERFERON GAMMA SIGNALING Genes involved in Interferon gamma signaling
0.0 0.1 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE