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ENCODE: H3K4me1 ChIP-Seq of primary human cells
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Results for NRF1

Z-value: 2.34

Motif logo

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Transcription factors associated with NRF1

Gene Symbol Gene ID Gene Info
NRF1
ENSG00000106459.10 nuclear respiratory factor 1

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE Gene Distance Association probability Pearson corr. coef. P-value Plot
chr7_129256455_129256630NRF149450.2676550.853.5e-03Click!
chr7_129247444_129247595NRF140360.2824380.791.2e-02Click!
chr7_129257593_129257892NRF161450.2558530.781.3e-02Click!
chr7_129257253_129257543NRF158010.2586100.761.7e-02Click!
chr7_129338608_129338759NRF1414920.1291600.761.8e-02Click!

Activity of the NRF1 motif across conditions

Conditions sorted by the z-value of the NRF1 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE) Target Score Top associated gene Gene Info Distance of CRE to TSS CRE/Gene association probability
chr19_5720411_5720610 1.55 LONP1
 lon peptidase 1, mitochondrial
 73
 0.64
chr2_54557855_54558006 1.42 C2orf73
 chromosome 2 open reading frame 73
 109
 0.98
chr1_148555913_148556064 1.22 NBPF15
 neuroblastoma breakpoint family, member 15
 4855
 0.29
chr16_71598808_71599043 1.19 ZNF19
 zinc finger protein 19
 67
 0.9
chr10_70231708_70231916 1.16 DNA2
 DNA replication helicase/nuclease 2
 67
 0.97
chr8_13424222_13424373 1.11 C8orf48
 chromosome 8 open reading frame 48
 55
 0.98
chr20_35580051_35580202 1.09 SAMHD1
 SAM domain and HD domain 1
 15
 0.98
chr9_90341033_90341185 0.98 CTSL
 cathepsin L
 54
 0.98
chr1_21766485_21766636 0.98 NBPF3
 neuroblastoma breakpoint family, member 3
 61
 0.98
chr19_56165348_56165561 0.96 U2AF2
 U2 small nuclear RNA auxiliary factor 2
 58
 0.92
chr3_126249831_126249990 0.94 CHST13
 carbohydrate (chondroitin 4) sulfotransferase 13
 6784
 0.15
chr1_156426435_156426586 0.92 MEF2D
 myocyte enhancer factor 2D
 26712
 0.1
chrX_7066682_7066833 0.89 HDHD1
 haloacid dehalogenase-like hydrolase domain containing 1
 526
 0.63
chr19_984644_984884 0.88 WDR18
 WD repeat domain 18
 406
 0.67
chr9_137030102_137030253 0.88 ENSG00000221676
 .
 491
 0.8
chr13_53030087_53030240 0.88 CKAP2
 cytoskeleton associated protein 2
 20
 0.98
chr21_34676896_34677104 0.84 IFNAR1
 interferon (alpha, beta and omega) receptor 1
 19734
 0.14
chr19_42704508_42704707 0.83 ENSG00000265122
 .
 7377
 0.09
chr17_9479898_9480049 0.83 WDR16
 WD repeat domain 16
 26
 0.53
chr1_33178018_33178177 0.83 SYNC
 syncoilin, intermediate filament protein
 8900
 0.14
chr5_1594545_1594696 0.80 SDHAP3
 succinate dehydrogenase complex, subunit A, flavoprotein pseudogene 3
 1216
 0.52
chr2_232526773_232526924 0.79 ENSG00000239202
 .
 15864
 0.16
chr19_57351053_57351204 0.77 PEG3
 paternally expressed 3
 936
 0.39
chr3_127397139_127397377 0.76 ABTB1
 ankyrin repeat and BTB (POZ) domain containing 1
 4305
 0.2
chr17_28256827_28256978 0.75 EFCAB5
 EF-hand calcium binding domain 5
 19
 0.69
chr21_37432862_37433013 0.75 SETD4
 SET domain containing 4
 89
 0.66
chr2_37311432_37311583 0.74 HEATR5B
 HEAT repeat containing 5B
 22
 0.56
chr1_91966289_91966440 0.73 CDC7
 cell division cycle 7
 44
 0.99
chr19_44905748_44905899 0.71 CTC-512J12.6
 Uncharacterized protein
 49
 0.49
chr9_131580381_131580656 0.71 ENDOG
 endonuclease G
 235
 0.88
chr11_67798369_67798520 0.70 NDUFS8
 NADH dehydrogenase (ubiquinone) Fe-S protein 8, 23kDa (NADH-coenzyme Q reductase)
 11
 0.89
chr11_118747067_118747433 0.68 CXCR5
 chemokine (C-X-C motif) receptor 5
 7225
 0.11
chr2_27193407_27193558 0.68 MAPRE3
 microtubule-associated protein, RP/EB family, member 3
 2
 0.97
chr20_48887426_48887577 0.67 CEBPB
 CCAAT/enhancer binding protein (C/EBP), beta
 80125
 0.09
chr2_132250270_132250421 0.67 MZT2A
 mitotic spindle organizing protein 2A
 350
 0.82
chr12_31479035_31479186 0.66 FAM60A
 family with sequence similarity 60, member A
 23
 0.97
chr1_1565793_1565944 0.66 MMP23B
 matrix metallopeptidase 23B
 1606
 0.19
chr1_226288352_226288545 0.65 H3F3A
 H3 histone, family 3A
 36770
 0.12
chr2_60529375_60529530 0.65 ENSG00000200807
 .
 82288
 0.1
chr10_38147005_38147159 0.64 ZNF248
 zinc finger protein 248
 48
 0.87
chrX_54384114_54384370 0.64 WNK3
 WNK lysine deficient protein kinase 3
 196
 0.95
chr19_36288681_36288832 0.64 PRODH2
 proline dehydrogenase (oxidase) 2
 8592
 0.08
chr4_186317556_186317707 0.64 ANKRD37
 ankyrin repeat domain 37
 7
 0.91
chr11_86013559_86013710 0.62 C11orf73
 chromosome 11 open reading frame 73
 369
 0.87
chr19_5622910_5623061 0.62 SAFB2
 scaffold attachment factor B2
 6
 0.62
chr16_3550197_3550348 0.62 CLUAP1
 clusterin associated protein 1
 652
 0.6
chr16_77756350_77756501 0.61 NUDT7
 nudix (nucleoside diphosphate linked moiety X)-type motif 7
 9
 0.98
chr19_10341660_10341820 0.60 S1PR2
 sphingosine-1-phosphate receptor 2
 208
 0.44
chr19_40030863_40031014 0.59 EID2
 EP300 interacting inhibitor of differentiation 2
 68
 0.95
chr1_155293264_155293415 0.59 RUSC1
 RUN and SH3 domain containing 1
 389
 0.54
chr17_73511759_73511998 0.58 CASKIN2
 CASK interacting protein 2
 214
 0.53
chr19_2236509_2236694 0.58 SF3A2
 splicing factor 3a, subunit 2, 66kDa
 81
 0.73
chr3_183735605_183735756 0.58 ABCC5
 ATP-binding cassette, sub-family C (CFTR/MRP), member 5
 3
 0.96
chr5_36151393_36151544 0.57 LMBRD2
 LMBR1 domain containing 2
 595
 0.42
chr9_95824447_95824598 0.57 SUSD3
 sushi domain containing 3
 3461
 0.22
chr19_4304476_4304627 0.57 FSD1
 fibronectin type III and SPRY domain containing 1
 46
 0.94
chr14_69095018_69095177 0.57 CTD-2325P2.4
65
 0.98
chr12_110841788_110841939 0.57 ANAPC7
 anaphase promoting complex subunit 7
 328
 0.86
chr4_9383016_9383167 0.56 RP11-1396O13.13
 Uncharacterized protein
 7618
 0.09
chr8_90769274_90769561 0.56 RIPK2
 receptor-interacting serine-threonine kinase 2
 558
 0.86
chr16_4234049_4234200 0.56 SRL
 sarcalumenin
 55620
 0.11
chr4_144105446_144105650 0.56 RP11-284M14.1
434
 0.54
chr1_111888969_111889259 0.56 PIFO
 primary cilia formation
 128
 0.94
chr20_3732710_3732861 0.56 C20orf27
 chromosome 20 open reading frame 27
 6540
 0.13
chr10_134330835_134330986 0.55 LINC01165
 long intergenic non-protein coding RNA 1165
 5043
 0.22
chr9_140173416_140173607 0.55 TOR4A
 torsin family 4, member A
 1310
 0.22
chr14_100613610_100613932 0.55 DEGS2
 delta(4)-desaturase, sphingolipid 2
 12161
 0.13
chr1_35734135_35734286 0.55 ZMYM4
 zinc finger, MYM-type 4
 358
 0.83
chr19_46002008_46002210 0.54 PPM1N
 protein phosphatase, Mg2+/Mn2+ dependent, 1N (putative)
 244
 0.85
chr1_35497458_35497682 0.54 ZMYM6
 zinc finger, MYM-type 6
 1
 0.97
chr2_86667774_86667925 0.54 KDM3A
 lysine (K)-specific demethylase 3A
 75
 0.98
chr4_2470999_2471186 0.54 RNF4
 ring finger protein 4
 88
 0.97
chr12_101673837_101673988 0.53 UTP20
 UTP20, small subunit (SSU) processome component, homolog (yeast)
 25
 0.98
chr22_20307835_20307986 0.53 DGCR6L
 DiGeorge syndrome critical region gene 6-like
 307
 0.82
chr8_48872569_48872812 0.53 PRKDC
 protein kinase, DNA-activated, catalytic polypeptide
 53
 0.5
chr22_19753186_19753429 0.53 TBX1
 T-box 1
 9081
 0.18
chr15_90319837_90320135 0.52 MESP2
 mesoderm posterior 2 homolog (mouse)
 397
 0.79
chr8_124429092_124429243 0.52 WDYHV1
 WDYHV motif containing 1
 114
 0.88
chr13_36920806_36920957 0.52 SPG20
 spastic paraplegia 20 (Troyer syndrome)
 53
 0.8
chr19_42700896_42701078 0.52 ENSG00000265122
 .
 3757
 0.12
chr19_6199822_6199973 0.52 RFX2
 regulatory factor X, 2 (influences HLA class II expression)
 357
 0.86
chr6_150312211_150312428 0.50 RAET1K
 retinoic acid early transcript 1K pseudogene
 13974
 0.14
chr4_120221761_120221912 0.50 C4orf3
 chromosome 4 open reading frame 3
 240
 0.93
chr12_56224471_56224622 0.49 DNAJC14
 DnaJ (Hsp40) homolog, subfamily C, member 14
 19
 0.95
chr5_14011611_14011857 0.49 DNAH5
 dynein, axonemal, heavy chain 5
 67082
 0.14
chr19_50837044_50837211 0.49 KCNC3
 potassium voltage-gated channel, Shaw-related subfamily, member 3
 355
 0.76
chr3_143690707_143690858 0.49 C3orf58
 chromosome 3 open reading frame 58
 142
 0.98
chr1_14075543_14075694 0.49 PRDM2
 PR domain containing 2, with ZNF domain
 280
 0.94
chrX_71130790_71130953 0.48 NHSL2
 NHS-like 2
 67
 0.98
chr17_78389255_78389406 0.48 ENDOV
 endonuclease V
 43
 0.84
chr9_78506329_78506658 0.48 PCSK5
 proprotein convertase subtilisin/kexin type 5
 872
 0.69
chr12_112546642_112546922 0.48 NAA25
 N(alpha)-acetyltransferase 25, NatB auxiliary subunit
 44
 0.97
chr19_18314394_18314545 0.48 RAB3A
 RAB3A, member RAS oncogene family
 353
 0.7
chr1_228645755_228646056 0.47 HIST3H2BB
 histone cluster 3, H2bb
 97
 0.77
chr13_37004479_37004630 0.47 CCNA1
 cyclin A1
 1413
 0.47
chr13_74710087_74710337 0.47 KLF12
 Kruppel-like factor 12
 1818
 0.52
chr1_33282657_33282808 0.47 S100PBP
 S100P binding protein
 311
 0.79
chr19_38397367_38397576 0.47 WDR87
 WD repeat domain 87
 154
 0.77
chr19_14628854_14629005 0.46 DNAJB1
 DnaJ (Hsp40) homolog, subfamily B, member 1
 284
 0.83
chr5_69320928_69321079 0.46 SERF1B
 small EDRK-rich factor 1B (centromeric)
 71
 0.98
chr3_48440225_48440376 0.46 ENSG00000265053
 .
 18976
 0.09
chr2_219575344_219575495 0.46 TTLL4
 tubulin tyrosine ligase-like family, member 4
 149
 0.93
chr9_131266777_131266928 0.46 GLE1
 GLE1 RNA export mediator
 127
 0.93
chrX_51636592_51636863 0.46 MAGED1
 melanoma antigen family D, 1
 8
 0.98
chr15_34729955_34730118 0.46 GOLGA8A
 golgin A8 family, member A
 30148
 0.13
chr17_1157162_1157402 0.46 BHLHA9
 basic helix-loop-helix family, member a9
 16571
 0.16
chr12_117491412_117491563 0.46 TESC
 tescalcin
 6851
 0.27
chr5_10250493_10250644 0.45 CCT5
 chaperonin containing TCP1, subunit 5 (epsilon)
 81
 0.88
chr21_43430032_43430183 0.45 ZBTB21
 zinc finger and BTB domain containing 21
 359
 0.88
chr7_72476062_72476213 0.45 STAG3L3
 stromal antigen 3-like 3
 303
 0.81
chr19_15236583_15236734 0.45 ILVBL
 ilvB (bacterial acetolactate synthase)-like
 62
 0.95
chr4_118006654_118006805 0.45 TRAM1L1
 translocation associated membrane protein 1-like 1
 7
 0.99
chr16_67197044_67197250 0.45 HSF4
 heat shock transcription factor 4
 141
 0.87
chr3_58223698_58223849 0.45 ABHD6
 abhydrolase domain containing 6
 18
 0.98
chr7_130126161_130126414 0.45 MEST
 mesoderm specific transcript
 92
 0.72
chrX_15692710_15693088 0.44 CA5BP1
 carbonic anhydrase VB pseudogene 1
 6277
 0.16
chr5_178368081_178368232 0.44 ZNF454
 zinc finger protein 454
 36
 0.97
chr4_185781728_185781907 0.44 ENSG00000266698
 .
 9553
 0.2
chr22_50320723_50320874 0.44 CRELD2
 cysteine-rich with EGF-like domains 2
 8417
 0.17
chrX_103086687_103086838 0.43 RAB9B
 RAB9B, member RAS oncogene family
 396
 0.81
chr17_56407049_56407274 0.43 BZRAP1-AS1
 BZRAP1 antisense RNA 1
 195
 0.84
chr9_35812077_35812228 0.43 SPAG8
 sperm associated antigen 8
 9
 0.89
chr4_178231232_178232008 0.43 NEIL3
 nei endonuclease VIII-like 3 (E. coli)
 630
 0.77
chr8_56885039_56885250 0.43 ENSG00000240905
 .
 7952
 0.16
chr1_55265824_55265995 0.43 TTC22
 tetratricopeptide repeat domain 22
 962
 0.46
chr18_3451483_3451634 0.43 TGIF1
 TGFB-induced factor homeobox 1
 33
 0.98
chr10_134043808_134044058 0.43 DPYSL4
 dihydropyrimidinase-like 4
 37669
 0.15
chr16_30198438_30198649 0.42 RP11-455F5.5
2265
 0.12
chr2_70165909_70166060 0.42 ENSG00000239072
 .
 16793
 0.11
chr19_40854574_40854725 0.42 PLD3
 phospholipase D family, member 3
 38
 0.71
chrX_83443462_83443613 0.42 RPS6KA6
 ribosomal protein S6 kinase, 90kDa, polypeptide 6
 604
 0.82
chr22_50338301_50338522 0.41 PIM3
 pim-3 oncogene
 15750
 0.16
chr12_66135927_66136146 0.41 HMGA2
 high mobility group AT-hook 2
 81875
 0.1
chr1_149783736_149783887 0.41 HIST2H2BF
 histone cluster 2, H2bf
 103
 0.8
chr20_30326551_30326940 0.40 TPX2
 TPX2, microtubule-associated
 329
 0.84
chr19_7968215_7968452 0.40 AC010336.1
 Uncharacterized protein
 94
 0.76
chr19_983876_984257 0.40 WDR18
 WD repeat domain 18
 265
 0.8
chr1_234614717_234614988 0.40 TARBP1
 TAR (HIV-1) RNA binding protein 1
 3
 0.98
chr15_31196174_31196325 0.40 FAN1
 FANCD2/FANCI-associated nuclease 1
 153
 0.95
chr16_89753037_89753188 0.39 CDK10
 cyclin-dependent kinase 10
 2
 0.62
chr2_164592385_164592622 0.39 FIGN
 fidgetin
 14
 0.99
chr15_77197791_77197942 0.39 SCAPER
 S-phase cyclin A-associated protein in the ER
 81
 0.98
chr16_46776734_46777089 0.39 MYLK3
 myosin light chain kinase 3
 5310
 0.22
chr21_34863671_34863822 0.39 DNAJC28
 DnaJ (Hsp40) homolog, subfamily C, member 28
 34
 0.96
chr19_1592993_1593266 0.39 MBD3
 methyl-CpG binding domain protein 3
 247
 0.83
chr18_77906315_77906466 0.38 AC139100.2
 Uncharacterized protein
 458
 0.82
chr1_53780929_53781080 0.38 RP4-784A16.4
10796
 0.12
chr20_19738439_19738726 0.38 AL121761.2
 Uncharacterized protein
 97
 0.97
chr19_52074425_52074576 0.38 ZNF175
 zinc finger protein 175
 51
 0.96
chr15_37393541_37393790 0.38 MEIS2
 Meis homeobox 2
 161
 0.95
chr19_10862270_10862475 0.38 ENSG00000265879
 .
 28558
 0.1
chr16_73092870_73093114 0.38 ZFHX3
 zinc finger homeobox 3
 605
 0.79
chr10_135207417_135207593 0.38 MTG1
 mitochondrial ribosome-associated GTPase 1
 93
 0.92
chr17_77005992_77006143 0.37 CANT1
 calcium activated nucleotidase 1
 118
 0.95
chr17_18280736_18280966 0.37 EVPLL
 envoplakin-like
 125
 0.94
chr1_32230053_32230204 0.37 BAI2
 brain-specific angiogenesis inhibitor 2
 187
 0.92
chr2_242743291_242743442 0.37 AC114730.5
2044
 0.18
chr11_11627396_11627547 0.36 GALNT18
 UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 18
 16081
 0.21
chr10_88699358_88699606 0.36 MMRN2
 multimerin 2
 14533
 0.11
chr7_152161795_152161946 0.36 ENSG00000221454
 .
 25564
 0.17
chr2_100669213_100669364 0.36 AFF3
 AF4/FMR2 family, member 3
 51704
 0.15
chr12_102036225_102036376 0.36 RP11-755O11.2
8426
 0.18
chr20_18447924_18448075 0.36 DZANK1
 double zinc ribbon and ankyrin repeat domains 1
 170
 0.56
chr3_138327624_138327830 0.36 FAIM
 Fas apoptotic inhibitory molecule
 34
 0.98
chr12_54423414_54423572 0.36 HOXC6
 homeobox C6
 1351
 0.19
chr20_32255046_32255197 0.36 NECAB3
 N-terminal EF-hand calcium binding protein 3
 656
 0.4
chr20_1206742_1206987 0.36 RAD21L1
 RAD21-like 1 (S. pombe)
 85
 0.96
chr2_12606087_12606238 0.36 ENSG00000207183
 .
 54535
 0.17
chr3_8543429_8543580 0.36 LMCD1
 LIM and cysteine-rich domains 1
 5
 0.68
chr3_30706089_30706316 0.36 RP11-1024P17.1
32951
 0.22
chr6_139751073_139751282 0.36 CITED2
 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2
 55420
 0.16
chr17_8533868_8534019 0.35 MYH10
 myosin, heavy chain 10, non-muscle
 92
 0.98
chr14_65521112_65521288 0.35 ENSG00000266531
 .
 9794
 0.14
chr12_116990313_116990698 0.35 MAP1LC3B2
 microtubule-associated protein 1 light chain 3 beta 2
 6681
 0.3
chr16_67197519_67197670 0.35 HSF4
 heat shock transcription factor 4
 306
 0.71
chr17_1733003_1733154 0.35 RPA1
 replication protein A1, 70kDa
 82
 0.38
chr3_169530773_169530924 0.35 LRRC34
 leucine rich repeat containing 34
 74
 0.95
chr19_45147070_45147221 0.35 PVR
 poliovirus receptor
 47
 0.96
chr16_70099999_70100211 0.35 PDXDC2P
426
 0.81
chr5_150138680_150138831 0.35 DCTN4
 dynactin 4 (p62)
 84
 0.96
chr3_44379599_44379750 0.35 TCAIM
 T cell activation inhibitor, mitochondrial
 63
 0.84
chr1_56106899_56107085 0.35 ENSG00000272051
 .
 156347
 0.04
chr3_128845918_128846069 0.34 RP11-434H6.6
3711
 0.15
chr11_70245830_70245981 0.34 CTTN
 cortactin
 1258
 0.29
chr6_27806448_27806599 0.34 HIST1H2BN
 histone cluster 1, H2bn
 83
 0.8
chr11_73358538_73358798 0.34 PLEKHB1
 pleckstrin homology domain containing, family B (evectins) member 1
 3
 0.98
chr14_23306505_23306782 0.34 MMP14
 matrix metallopeptidase 14 (membrane-inserted)
 122
 0.91
chr19_1676280_1676431 0.34 TCF3
 transcription factor 3
 23751
 0.11
chr1_10856635_10856901 0.34 CASZ1
 castor zinc finger 1
 61
 0.98
chr7_6388633_6388784 0.34 FAM220A
 family with sequence similarity 220, member A
 102
 0.97
chr16_75182292_75182443 0.33 ZFP1
 ZFP1 zinc finger protein
 23
 0.97
chr8_98881347_98881636 0.33 MATN2
 matrilin 2
 109
 0.98
chr5_122372371_122372688 0.33 PPIC
 peptidylprolyl isomerase C (cyclophilin C)
 93
 0.88
chr14_75518210_75518414 0.33 MLH3
 mutL homolog 3
 77
 0.95
chr19_48613677_48613862 0.33 PLA2G4C
 phospholipase A2, group IVC (cytosolic, calcium-independent)
 51
 0.96
chr15_67357185_67357431 0.33 SMAD3
 SMAD family member 3
 875
 0.72
chr1_153536660_153536811 0.33 S100A2
 S100 calcium binding protein A2
 26
 0.94
chr8_117887280_117887466 0.33 RAD21
 RAD21 homolog (S. pombe)
 268
 0.51
chr8_61627450_61627601 0.33 CHD7
 chromodomain helicase DNA binding protein 7
 26399
 0.24
chr15_100049975_100050265 0.33 AC015660.1
 HCG1993240; Serologically defined breast cancer antigen NY-BR-40; Uncharacterized protein
 11542
 0.22

Histogram of CRE-TSS distances for CREs targeted by :

Histogram of

Rank distribution of CRE target scores:

Histogram of target CRE score.

Distribution of target CREs across different genomic regions:

Weighted Piechart of Weighted Piechart of Weighted Piechart of

Network of associatons between targets according to the STRING database.

First level regulatory network of NRF1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 2.1 GO:0032042 mitochondrial DNA metabolic process(GO:0032042)
0.2 0.8 GO:0090224 regulation of spindle organization(GO:0090224)
0.2 0.6 GO:0007181 transforming growth factor beta receptor complex assembly(GO:0007181)
0.2 0.5 GO:0000966 RNA 5'-end processing(GO:0000966)
0.2 1.2 GO:0033169 histone H3-K9 demethylation(GO:0033169)
0.2 0.5 GO:0071224 cellular response to peptidoglycan(GO:0071224)
0.2 0.5 GO:0010216 maintenance of DNA methylation(GO:0010216)
0.1 0.8 GO:0033261 obsolete regulation of S phase(GO:0033261)
0.1 0.6 GO:0009109 coenzyme catabolic process(GO:0009109)
0.1 0.4 GO:0042271 susceptibility to natural killer cell mediated cytotoxicity(GO:0042271)
0.1 0.3 GO:2000300 regulation of synaptic vesicle transport(GO:1902803) regulation of synaptic vesicle exocytosis(GO:2000300)
0.1 0.2 GO:0031936 negative regulation of chromatin silencing(GO:0031936)
0.1 0.3 GO:0060394 negative regulation of pathway-restricted SMAD protein phosphorylation(GO:0060394)
0.1 0.4 GO:0006930 substrate-dependent cell migration, cell extension(GO:0006930)
0.1 0.2 GO:0060528 secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development(GO:0060528)
0.1 0.4 GO:0032455 nerve growth factor processing(GO:0032455)
0.1 0.3 GO:0042996 regulation of Golgi to plasma membrane protein transport(GO:0042996)
0.1 0.4 GO:0006346 methylation-dependent chromatin silencing(GO:0006346)
0.1 0.3 GO:0002328 pro-B cell differentiation(GO:0002328)
0.1 0.5 GO:0000389 mRNA 3'-splice site recognition(GO:0000389)
0.1 0.4 GO:0043615 astrocyte cell migration(GO:0043615)
0.1 0.3 GO:0033314 mitotic DNA replication checkpoint(GO:0033314)
0.1 0.2 GO:0071635 negative regulation of transforming growth factor beta production(GO:0071635)
0.1 0.2 GO:0033173 calcineurin-NFAT signaling cascade(GO:0033173)
0.1 0.2 GO:0051834 evasion or tolerance of host defenses by virus(GO:0019049) avoidance of host defenses(GO:0044413) evasion or tolerance of host defenses(GO:0044415) avoidance of defenses of other organism involved in symbiotic interaction(GO:0051832) evasion or tolerance of defenses of other organism involved in symbiotic interaction(GO:0051834)
0.1 0.2 GO:0051964 negative regulation of synapse assembly(GO:0051964)
0.1 0.4 GO:0070389 chaperone cofactor-dependent protein refolding(GO:0070389)
0.1 0.4 GO:0045662 negative regulation of myoblast differentiation(GO:0045662)
0.1 0.2 GO:0033148 positive regulation of intracellular estrogen receptor signaling pathway(GO:0033148)
0.1 0.4 GO:0016973 poly(A)+ mRNA export from nucleus(GO:0016973)
0.1 0.2 GO:0021819 layer formation in cerebral cortex(GO:0021819)
0.1 0.2 GO:0045715 negative regulation of low-density lipoprotein particle receptor biosynthetic process(GO:0045715)
0.1 0.3 GO:0009249 protein lipoylation(GO:0009249)
0.1 0.3 GO:0032486 Rap protein signal transduction(GO:0032486)
0.1 0.6 GO:0097031 NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.1 0.2 GO:0019367 fatty acid elongation, saturated fatty acid(GO:0019367)
0.1 0.5 GO:0006895 Golgi to endosome transport(GO:0006895) Golgi to vacuole transport(GO:0006896)
0.1 0.4 GO:0033683 nucleotide-excision repair, DNA incision(GO:0033683)
0.1 0.2 GO:0043552 positive regulation of phosphatidylinositol 3-kinase activity(GO:0043552)
0.1 0.3 GO:0000394 RNA splicing, via endonucleolytic cleavage and ligation(GO:0000394) tRNA splicing, via endonucleolytic cleavage and ligation(GO:0006388)
0.1 0.3 GO:0046475 glycerophospholipid catabolic process(GO:0046475)
0.1 0.2 GO:0009169 purine nucleoside monophosphate catabolic process(GO:0009128) ribonucleoside monophosphate catabolic process(GO:0009158) purine ribonucleoside monophosphate catabolic process(GO:0009169)
0.1 0.3 GO:0042984 amyloid precursor protein biosynthetic process(GO:0042983) regulation of amyloid precursor protein biosynthetic process(GO:0042984)
0.1 0.2 GO:0019372 lipoxygenase pathway(GO:0019372)
0.0 0.1 GO:0051451 myoblast migration(GO:0051451)
0.0 0.1 GO:0032467 positive regulation of cytokinesis(GO:0032467)
0.0 0.2 GO:0032007 negative regulation of TOR signaling(GO:0032007)
0.0 0.1 GO:0003161 cardiac conduction system development(GO:0003161)
0.0 0.3 GO:0001561 fatty acid alpha-oxidation(GO:0001561)
0.0 0.2 GO:0061029 eyelid development in camera-type eye(GO:0061029)
0.0 0.2 GO:0070120 ciliary neurotrophic factor-mediated signaling pathway(GO:0070120)
0.0 0.1 GO:1901534 positive regulation of megakaryocyte differentiation(GO:0045654) positive regulation of hematopoietic progenitor cell differentiation(GO:1901534)
0.0 0.2 GO:0007089 traversing start control point of mitotic cell cycle(GO:0007089) positive regulation of G1/S transition of mitotic cell cycle(GO:1900087) positive regulation of cell cycle G1/S phase transition(GO:1902808)
0.0 0.2 GO:0051409 response to nitrosative stress(GO:0051409)
0.0 0.1 GO:0035520 monoubiquitinated protein deubiquitination(GO:0035520)
0.0 0.1 GO:0001560 regulation of cell growth by extracellular stimulus(GO:0001560)
0.0 0.1 GO:0097501 detoxification of inorganic compound(GO:0061687) stress response to metal ion(GO:0097501)
0.0 0.1 GO:0010803 regulation of tumor necrosis factor-mediated signaling pathway(GO:0010803)
0.0 0.2 GO:0071168 protein localization to chromatin(GO:0071168)
0.0 0.1 GO:0009648 photoperiodism(GO:0009648)
0.0 0.3 GO:0010591 regulation of lamellipodium assembly(GO:0010591)
0.0 0.4 GO:0007128 meiotic prophase I(GO:0007128)
0.0 0.1 GO:0071318 cellular response to ATP(GO:0071318)
0.0 0.1 GO:0006548 histidine catabolic process(GO:0006548) imidazole-containing compound catabolic process(GO:0052805)
0.0 0.5 GO:0018200 peptidyl-glutamic acid modification(GO:0018200)
0.0 0.1 GO:0010842 retina layer formation(GO:0010842)
0.0 0.1 GO:0000089 mitotic metaphase(GO:0000089)
0.0 0.1 GO:0007144 female meiosis I(GO:0007144)
0.0 0.1 GO:0009226 nucleotide-sugar biosynthetic process(GO:0009226)
0.0 0.4 GO:0048873 homeostasis of number of cells within a tissue(GO:0048873)
0.0 0.1 GO:0010800 positive regulation of peptidyl-threonine phosphorylation(GO:0010800)
0.0 0.1 GO:0060298 positive regulation of sarcomere organization(GO:0060298)
0.0 0.2 GO:0031115 negative regulation of microtubule polymerization(GO:0031115)
0.0 0.1 GO:0006572 tyrosine catabolic process(GO:0006572)
0.0 0.1 GO:0033345 asparagine catabolic process(GO:0006530) asparagine catabolic process via L-aspartate(GO:0033345)
0.0 0.1 GO:0048172 regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.0 0.1 GO:0007028 cytoplasm organization(GO:0007028)
0.0 0.2 GO:0006744 ubiquinone metabolic process(GO:0006743) ubiquinone biosynthetic process(GO:0006744)
0.0 0.1 GO:0021778 spinal cord oligodendrocyte cell differentiation(GO:0021529) spinal cord oligodendrocyte cell fate specification(GO:0021530) oligodendrocyte cell fate specification(GO:0021778) glial cell fate specification(GO:0021780)
0.0 0.1 GO:0033522 histone H2A ubiquitination(GO:0033522)
0.0 0.6 GO:0046677 response to antibiotic(GO:0046677)
0.0 0.1 GO:0007130 synaptonemal complex assembly(GO:0007130)
0.0 0.0 GO:0060839 endothelial cell fate commitment(GO:0060839)
0.0 0.0 GO:0002513 tolerance induction to self antigen(GO:0002513)
0.0 0.0 GO:0032025 response to cobalt ion(GO:0032025)
0.0 0.3 GO:0060765 regulation of androgen receptor signaling pathway(GO:0060765)
0.0 0.1 GO:0006562 proline catabolic process(GO:0006562)
0.0 0.9 GO:0006369 termination of RNA polymerase II transcription(GO:0006369)
0.0 0.1 GO:0060536 trachea cartilage morphogenesis(GO:0060535) cartilage morphogenesis(GO:0060536)
0.0 0.1 GO:0046618 drug export(GO:0046618)
0.0 0.0 GO:0097576 vacuole fusion(GO:0097576)
0.0 0.4 GO:0000083 regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083)
0.0 0.1 GO:0006102 isocitrate metabolic process(GO:0006102)
0.0 0.1 GO:0060017 parathyroid gland development(GO:0060017)
0.0 0.0 GO:0032661 interleukin-18 production(GO:0032621) regulation of interleukin-18 production(GO:0032661)
0.0 0.0 GO:0072217 negative regulation of metanephros development(GO:0072217)
0.0 0.1 GO:0006391 transcription initiation from mitochondrial promoter(GO:0006391)
0.0 0.1 GO:0031062 positive regulation of histone methylation(GO:0031062)
0.0 0.5 GO:0070979 protein K11-linked ubiquitination(GO:0070979)
0.0 0.1 GO:1903672 positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050) positive regulation of sprouting angiogenesis(GO:1903672)
0.0 0.3 GO:0033598 mammary gland epithelial cell proliferation(GO:0033598)
0.0 0.1 GO:0035235 ionotropic glutamate receptor signaling pathway(GO:0035235)
0.0 0.1 GO:0010871 negative regulation of receptor biosynthetic process(GO:0010871)
0.0 0.1 GO:0021527 spinal cord association neuron differentiation(GO:0021527)
0.0 0.0 GO:0070779 D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
0.0 0.1 GO:0045661 regulation of myoblast differentiation(GO:0045661)
0.0 0.0 GO:0003197 endocardial cushion development(GO:0003197)
0.0 0.0 GO:0007506 gonadal mesoderm development(GO:0007506)
0.0 0.1 GO:0051299 centrosome separation(GO:0051299)
0.0 0.0 GO:0021779 oligodendrocyte cell fate commitment(GO:0021779)
0.0 0.1 GO:0060648 mammary gland bud morphogenesis(GO:0060648)
0.0 1.7 GO:0006334 nucleosome assembly(GO:0006334)
0.0 0.0 GO:0030210 heparin biosynthetic process(GO:0030210)
0.0 0.0 GO:0043570 embryonic genitalia morphogenesis(GO:0030538) maintenance of DNA repeat elements(GO:0043570)
0.0 0.0 GO:0007090 obsolete regulation of S phase of mitotic cell cycle(GO:0007090)
0.0 0.0 GO:0031117 positive regulation of microtubule depolymerization(GO:0031117)
0.0 0.1 GO:0007216 G-protein coupled glutamate receptor signaling pathway(GO:0007216)
0.0 0.1 GO:0006878 cellular copper ion homeostasis(GO:0006878)
0.0 0.1 GO:0006384 transcription initiation from RNA polymerase III promoter(GO:0006384)
0.0 0.1 GO:0030540 female genitalia development(GO:0030540)
0.0 0.1 GO:0016075 rRNA catabolic process(GO:0016075)
0.0 0.0 GO:0060575 intestinal epithelial cell differentiation(GO:0060575)
0.0 0.1 GO:0006975 DNA damage induced protein phosphorylation(GO:0006975)
0.0 0.1 GO:0003310 pancreatic A cell differentiation(GO:0003310)
0.0 0.1 GO:0060539 diaphragm development(GO:0060539)
0.0 0.2 GO:0032728 positive regulation of interferon-beta production(GO:0032728)
0.0 0.2 GO:0030206 chondroitin sulfate biosynthetic process(GO:0030206)
0.0 0.0 GO:0051569 regulation of histone H3-K4 methylation(GO:0051569)
0.0 0.0 GO:0046668 regulation of retinal cell programmed cell death(GO:0046668)
0.0 0.1 GO:0043985 histone H4-R3 methylation(GO:0043985)
0.0 0.1 GO:0010042 response to manganese ion(GO:0010042)
0.0 0.3 GO:0007131 reciprocal meiotic recombination(GO:0007131) reciprocal DNA recombination(GO:0035825)
0.0 0.5 GO:0006284 base-excision repair(GO:0006284)
0.0 0.1 GO:0034587 piRNA metabolic process(GO:0034587)
0.0 0.3 GO:0006270 DNA replication initiation(GO:0006270)
0.0 0.0 GO:0016080 synaptic vesicle targeting(GO:0016080)
0.0 0.3 GO:0051225 spindle assembly(GO:0051225)
0.0 0.1 GO:0048712 negative regulation of astrocyte differentiation(GO:0048712)
0.0 0.1 GO:0050665 hydrogen peroxide biosynthetic process(GO:0050665)
0.0 0.1 GO:0010259 multicellular organism aging(GO:0010259)
0.0 0.0 GO:0015740 C4-dicarboxylate transport(GO:0015740) aspartate transport(GO:0015810)
0.0 0.1 GO:0006108 malate metabolic process(GO:0006108)
0.0 0.0 GO:0001821 histamine secretion(GO:0001821)
0.0 0.1 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.0 0.0 GO:0050765 negative regulation of phagocytosis(GO:0050765)
0.0 0.0 GO:0043129 surfactant homeostasis(GO:0043129) chemical homeostasis within a tissue(GO:0048875)
0.0 0.3 GO:0007030 Golgi organization(GO:0007030)
0.0 0.0 GO:0035455 response to interferon-alpha(GO:0035455)
0.0 0.0 GO:0060218 hematopoietic stem cell differentiation(GO:0060218)
0.0 0.1 GO:0051016 barbed-end actin filament capping(GO:0051016)
0.0 0.0 GO:0042159 lipoprotein catabolic process(GO:0042159)
0.0 0.1 GO:0001547 antral ovarian follicle growth(GO:0001547)
0.0 0.1 GO:0019369 arachidonic acid metabolic process(GO:0019369)
0.0 0.1 GO:0048844 artery morphogenesis(GO:0048844)
0.0 0.0 GO:0031665 negative regulation of lipopolysaccharide-mediated signaling pathway(GO:0031665)
0.0 0.1 GO:0032096 negative regulation of response to food(GO:0032096)
0.0 0.1 GO:0060396 growth hormone receptor signaling pathway(GO:0060396) cellular response to growth hormone stimulus(GO:0071378)
0.0 0.1 GO:0043457 regulation of cellular respiration(GO:0043457)
0.0 0.0 GO:0042635 positive regulation of hair cycle(GO:0042635) positive regulation of hair follicle development(GO:0051798)
0.0 0.1 GO:0060317 cardiac epithelial to mesenchymal transition(GO:0060317)
0.0 0.1 GO:0009650 UV protection(GO:0009650)
0.0 0.1 GO:0060314 regulation of ryanodine-sensitive calcium-release channel activity(GO:0060314)
0.0 0.1 GO:0015853 adenine transport(GO:0015853)
0.0 0.1 GO:0060710 chorio-allantoic fusion(GO:0060710)
0.0 0.1 GO:0000154 rRNA modification(GO:0000154)
0.0 0.1 GO:0019720 Mo-molybdopterin cofactor biosynthetic process(GO:0006777) Mo-molybdopterin cofactor metabolic process(GO:0019720) molybdopterin cofactor biosynthetic process(GO:0032324) molybdopterin cofactor metabolic process(GO:0043545) prosthetic group metabolic process(GO:0051189)
0.0 0.2 GO:0015985 energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.0 0.0 GO:0019511 peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401) 4-hydroxyproline metabolic process(GO:0019471) peptidyl-proline hydroxylation(GO:0019511)
0.0 0.1 GO:0043249 erythrocyte maturation(GO:0043249)
0.0 0.0 GO:0009313 oligosaccharide catabolic process(GO:0009313)
0.0 0.1 GO:0045351 type I interferon biosynthetic process(GO:0045351)
0.0 0.1 GO:0034285 response to sucrose(GO:0009744) response to disaccharide(GO:0034285)
0.0 0.0 GO:0032898 neurotrophin production(GO:0032898)
0.0 0.0 GO:0007500 mesodermal cell fate determination(GO:0007500)
0.0 0.0 GO:0046325 negative regulation of glucose import(GO:0046325)
0.0 0.1 GO:0015937 coenzyme A biosynthetic process(GO:0015937)
0.0 0.0 GO:0019255 glucose 1-phosphate metabolic process(GO:0019255)
0.0 0.4 GO:0001756 somitogenesis(GO:0001756)
0.0 0.0 GO:0044268 multicellular organismal protein catabolic process(GO:0044254) protein digestion(GO:0044256) multicellular organismal macromolecule catabolic process(GO:0044266) multicellular organismal protein metabolic process(GO:0044268)
0.0 0.0 GO:0042819 pyridoxine metabolic process(GO:0008614) pyridoxine biosynthetic process(GO:0008615) vitamin B6 metabolic process(GO:0042816) vitamin B6 biosynthetic process(GO:0042819)
0.0 0.1 GO:0001960 negative regulation of cytokine-mediated signaling pathway(GO:0001960)
0.0 0.4 GO:0006490 dolichol-linked oligosaccharide biosynthetic process(GO:0006488) oligosaccharide-lipid intermediate biosynthetic process(GO:0006490)
0.0 0.1 GO:0042987 amyloid precursor protein catabolic process(GO:0042987)
0.0 0.1 GO:0042769 DNA damage response, detection of DNA damage(GO:0042769)
0.0 0.1 GO:0008611 ether lipid biosynthetic process(GO:0008611) glycerol ether biosynthetic process(GO:0046504) ether biosynthetic process(GO:1901503)
0.0 0.1 GO:0060039 pericardium development(GO:0060039)
0.0 0.1 GO:0007520 syncytium formation by plasma membrane fusion(GO:0000768) myoblast fusion(GO:0007520)
0.0 0.0 GO:0036465 synaptic vesicle recycling(GO:0036465) synaptic vesicle endocytosis(GO:0048488) clathrin-mediated endocytosis(GO:0072583)
0.0 0.1 GO:0015884 folic acid transport(GO:0015884)
0.0 0.4 GO:0051084 'de novo' posttranslational protein folding(GO:0051084)
0.0 0.2 GO:0006004 fucose metabolic process(GO:0006004)
0.0 0.0 GO:0090162 establishment of epithelial cell polarity(GO:0090162)
0.0 0.0 GO:0070837 dehydroascorbic acid transport(GO:0070837)
0.0 0.1 GO:0051568 histone H3-K4 methylation(GO:0051568)
0.0 0.1 GO:0006929 substrate-dependent cell migration(GO:0006929)
0.0 0.0 GO:0060437 lung growth(GO:0060437)
0.0 0.0 GO:0060502 positive regulation of epithelial cell proliferation involved in lung morphogenesis(GO:0060501) epithelial cell proliferation involved in lung morphogenesis(GO:0060502) regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000794)
0.0 0.0 GO:0060391 positive regulation of SMAD protein import into nucleus(GO:0060391)
0.0 0.0 GO:0045332 lipid translocation(GO:0034204) phospholipid translocation(GO:0045332)
0.0 0.1 GO:0051058 negative regulation of Ras protein signal transduction(GO:0046580) negative regulation of small GTPase mediated signal transduction(GO:0051058)
0.0 0.4 GO:0050680 negative regulation of epithelial cell proliferation(GO:0050680)
0.0 0.1 GO:0050901 leukocyte tethering or rolling(GO:0050901) leukocyte adhesion to vascular endothelial cell(GO:0061756)
0.0 0.0 GO:0018094 protein polyglycylation(GO:0018094)
0.0 0.0 GO:0070634 transepithelial ammonium transport(GO:0070634)
0.0 0.1 GO:0001954 positive regulation of cell-matrix adhesion(GO:0001954)
0.0 0.0 GO:0006154 adenosine catabolic process(GO:0006154)
0.0 0.1 GO:0006621 protein retention in ER lumen(GO:0006621) maintenance of protein localization in endoplasmic reticulum(GO:0035437)
0.0 0.0 GO:0009405 pathogenesis(GO:0009405)
0.0 0.0 GO:0045056 transcytosis(GO:0045056)
0.0 0.1 GO:0008334 histone mRNA metabolic process(GO:0008334)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.6 GO:0030688 preribosome, small subunit precursor(GO:0030688)
0.1 0.3 GO:0060200 clathrin-sculpted acetylcholine transport vesicle(GO:0060200) clathrin-sculpted acetylcholine transport vesicle membrane(GO:0060201)
0.1 0.9 GO:0042575 DNA polymerase complex(GO:0042575)
0.1 0.6 GO:0008274 gamma-tubulin large complex(GO:0000931) gamma-tubulin ring complex(GO:0008274)
0.1 0.4 GO:0030893 meiotic cohesin complex(GO:0030893)
0.1 0.4 GO:0005832 chaperonin-containing T-complex(GO:0005832)
0.1 0.2 GO:0071062 alphav-beta3 integrin-vitronectin complex(GO:0071062)
0.1 0.2 GO:0030934 anchoring collagen complex(GO:0030934)
0.1 0.1 GO:0000800 lateral element(GO:0000800)
0.1 0.5 GO:0005721 pericentric heterochromatin(GO:0005721)
0.1 0.3 GO:0005958 DNA-dependent protein kinase-DNA ligase 4 complex(GO:0005958)
0.0 0.2 GO:0005826 actomyosin contractile ring(GO:0005826)
0.0 0.5 GO:0030126 COPI vesicle coat(GO:0030126)
0.0 0.2 GO:0042599 lamellar body(GO:0042599)
0.0 0.2 GO:0031258 lamellipodium membrane(GO:0031258)
0.0 0.2 GO:0000137 Golgi cis cisterna(GO:0000137)
0.0 0.3 GO:0043190 ATP-binding cassette (ABC) transporter complex(GO:0043190)
0.0 0.0 GO:0034992 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.0 0.8 GO:0097610 cell division site(GO:0032153) cleavage furrow(GO:0032154) cell division site part(GO:0032155) cell surface furrow(GO:0097610)
0.0 0.3 GO:0042555 MCM complex(GO:0042555)
0.0 0.3 GO:0070652 HAUS complex(GO:0070652)
0.0 1.0 GO:0042645 mitochondrial nucleoid(GO:0042645)
0.0 0.2 GO:0016342 catenin complex(GO:0016342)
0.0 0.2 GO:0031527 filopodium membrane(GO:0031527)
0.0 0.1 GO:0008278 cohesin complex(GO:0008278)
0.0 0.1 GO:1903561 extracellular exosome(GO:0070062) extracellular vesicle(GO:1903561)
0.0 0.2 GO:0032040 small-subunit processome(GO:0032040)
0.0 0.1 GO:0014701 junctional sarcoplasmic reticulum membrane(GO:0014701)
0.0 0.2 GO:0005662 DNA replication factor A complex(GO:0005662)
0.0 0.1 GO:0071437 invadopodium(GO:0071437)
0.0 0.1 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.0 0.6 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.0 0.1 GO:0070776 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.0 0.3 GO:0000795 synaptonemal complex(GO:0000795)
0.0 0.5 GO:0005680 anaphase-promoting complex(GO:0005680)
0.0 0.1 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.0 0.1 GO:0005797 Golgi medial cisterna(GO:0005797)
0.0 0.0 GO:0071664 catenin-TCF7L2 complex(GO:0071664)
0.0 0.1 GO:0030894 alpha DNA polymerase:primase complex(GO:0005658) replisome(GO:0030894) nuclear replisome(GO:0043601)
0.0 0.7 GO:0030964 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0 0.9 GO:0000922 spindle pole(GO:0000922)
0.0 1.7 GO:0005777 peroxisome(GO:0005777) microbody(GO:0042579)
0.0 0.4 GO:0005796 Golgi lumen(GO:0005796)
0.0 0.1 GO:0030877 beta-catenin destruction complex(GO:0030877)
0.0 0.0 GO:0016533 cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533)
0.0 1.0 GO:0000786 nucleosome(GO:0000786)
0.0 0.2 GO:0030914 STAGA complex(GO:0030914)
0.0 0.2 GO:0045263 proton-transporting ATP synthase complex, coupling factor F(o)(GO:0045263)
0.0 0.1 GO:0005638 lamin filament(GO:0005638)
0.0 0.6 GO:0036064 ciliary basal body(GO:0036064)
0.0 0.1 GO:0035189 Rb-E2F complex(GO:0035189)
0.0 0.0 GO:0005896 interleukin-6 receptor complex(GO:0005896)
0.0 0.1 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.0 0.3 GO:0005637 nuclear inner membrane(GO:0005637)
0.0 0.3 GO:0000792 heterochromatin(GO:0000792)
0.0 0.3 GO:0030057 desmosome(GO:0030057)
0.0 0.1 GO:0045179 apical cortex(GO:0045179) cell cortex region(GO:0099738)
0.0 0.8 GO:0005643 nuclear pore(GO:0005643)
0.0 0.1 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
0.0 0.3 GO:0042612 MHC class I protein complex(GO:0042612)
0.0 0.3 GO:0015030 Cajal body(GO:0015030)
0.0 0.2 GO:0000421 autophagosome membrane(GO:0000421)
0.0 1.6 GO:0005681 spliceosomal complex(GO:0005681)
0.0 0.0 GO:0070022 transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.0 0.1 GO:0033018 sarcoplasmic reticulum lumen(GO:0033018)
0.0 0.0 GO:0071778 obsolete WINAC complex(GO:0071778)
0.0 0.3 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.0 0.2 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.0 0.2 GO:0005814 centriole(GO:0005814)
0.0 0.0 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.0 0.1 GO:0001772 immunological synapse(GO:0001772)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.0 GO:0051880 G-quadruplex DNA binding(GO:0051880)
0.3 1.5 GO:0017108 5'-flap endonuclease activity(GO:0017108)
0.2 0.5 GO:0042156 obsolete zinc-mediated transcriptional activator activity(GO:0042156)
0.1 0.6 GO:0003986 acetyl-CoA hydrolase activity(GO:0003986)
0.1 0.5 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.1 0.4 GO:0008321 Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.1 0.4 GO:0003696 satellite DNA binding(GO:0003696)
0.1 0.3 GO:0047499 calcium-independent phospholipase A2 activity(GO:0047499)
0.1 1.0 GO:0070742 C2H2 zinc finger domain binding(GO:0070742)
0.1 0.3 GO:0004677 DNA-dependent protein kinase activity(GO:0004677)
0.1 0.3 GO:0003680 AT DNA binding(GO:0003680)
0.1 0.4 GO:0030618 transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity(GO:0030618)
0.1 0.4 GO:0030976 thiamine pyrophosphate binding(GO:0030976)
0.1 0.3 GO:0000405 bubble DNA binding(GO:0000405)
0.1 0.6 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.1 0.3 GO:0005030 neurotrophin receptor activity(GO:0005030)
0.1 0.6 GO:0050700 CARD domain binding(GO:0050700)
0.1 0.2 GO:0004999 vasoactive intestinal polypeptide receptor activity(GO:0004999)
0.1 0.2 GO:0004886 9-cis retinoic acid receptor activity(GO:0004886)
0.1 0.2 GO:0043184 vascular endothelial growth factor receptor 2 binding(GO:0043184)
0.1 0.3 GO:0005072 transforming growth factor beta receptor, cytoplasmic mediator activity(GO:0005072)
0.1 0.2 GO:0004321 fatty-acyl-CoA synthase activity(GO:0004321)
0.1 0.3 GO:0070290 N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.1 0.4 GO:0017110 nucleoside-diphosphatase activity(GO:0017110)
0.1 0.2 GO:0030229 very-low-density lipoprotein particle receptor activity(GO:0030229)
0.1 0.2 GO:0008184 glycogen phosphorylase activity(GO:0008184)
0.1 0.2 GO:0004897 ciliary neurotrophic factor receptor activity(GO:0004897)
0.0 0.1 GO:0047756 chondroitin 4-sulfotransferase activity(GO:0047756)
0.0 0.3 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.0 0.2 GO:0004844 uracil DNA N-glycosylase activity(GO:0004844) deaminated base DNA N-glycosylase activity(GO:0097506)
0.0 0.1 GO:0052659 inositol-1,4,5-trisphosphate 5-phosphatase activity(GO:0052658) inositol-1,3,4,5-tetrakisphosphate 5-phosphatase activity(GO:0052659)
0.0 0.2 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.0 0.3 GO:0008020 G-protein coupled photoreceptor activity(GO:0008020)
0.0 0.3 GO:0016018 cyclosporin A binding(GO:0016018)
0.0 0.1 GO:0015562 efflux transmembrane transporter activity(GO:0015562)
0.0 0.6 GO:0004835 tubulin-tyrosine ligase activity(GO:0004835)
0.0 0.3 GO:0001671 ATPase activator activity(GO:0001671)
0.0 0.1 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
0.0 0.2 GO:0004791 thioredoxin-disulfide reductase activity(GO:0004791)
0.0 0.1 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.0 0.3 GO:0004551 nucleotide diphosphatase activity(GO:0004551)
0.0 0.2 GO:0004904 interferon receptor activity(GO:0004904)
0.0 0.2 GO:0042043 neurexin family protein binding(GO:0042043)
0.0 0.1 GO:0050693 LBD domain binding(GO:0050693)
0.0 0.2 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.0 0.2 GO:0004957 prostaglandin E receptor activity(GO:0004957)
0.0 0.1 GO:0048495 Roundabout binding(GO:0048495)
0.0 0.1 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.0 0.1 GO:0008241 peptidyl-dipeptidase activity(GO:0008241)
0.0 0.1 GO:0005152 interleukin-1 receptor antagonist activity(GO:0005152)
0.0 0.4 GO:0008171 O-methyltransferase activity(GO:0008171)
0.0 0.1 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.0 0.2 GO:0016565 obsolete general transcriptional repressor activity(GO:0016565)
0.0 0.3 GO:0008641 small protein activating enzyme activity(GO:0008641)
0.0 0.9 GO:0050681 androgen receptor binding(GO:0050681)
0.0 0.2 GO:0043208 glycosphingolipid binding(GO:0043208)
0.0 0.1 GO:0005148 prolactin receptor binding(GO:0005148)
0.0 0.1 GO:0046923 ER retention sequence binding(GO:0046923)
0.0 0.1 GO:0000295 adenine nucleotide transmembrane transporter activity(GO:0000295) purine nucleotide transmembrane transporter activity(GO:0015216)
0.0 0.1 GO:0004594 pantothenate kinase activity(GO:0004594)
0.0 0.1 GO:0050321 tau-protein kinase activity(GO:0050321)
0.0 0.1 GO:0004448 isocitrate dehydrogenase activity(GO:0004448)
0.0 0.6 GO:0051539 4 iron, 4 sulfur cluster binding(GO:0051539)
0.0 0.1 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.0 0.1 GO:0043559 insulin binding(GO:0043559)
0.0 0.3 GO:0001619 obsolete lysosphingolipid and lysophosphatidic acid receptor activity(GO:0001619)
0.0 0.3 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.0 0.0 GO:0050253 retinyl-palmitate esterase activity(GO:0050253)
0.0 0.1 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.0 0.3 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.0 0.1 GO:0050544 arachidonic acid binding(GO:0050544)
0.0 0.1 GO:0004596 peptide alpha-N-acetyltransferase activity(GO:0004596)
0.0 0.2 GO:0030553 cGMP binding(GO:0030553)
0.0 0.4 GO:0005520 insulin-like growth factor binding(GO:0005520)
0.0 0.1 GO:0016174 NAD(P)H oxidase activity(GO:0016174)
0.0 0.1 GO:0000268 peroxisome targeting sequence binding(GO:0000268)
0.0 1.4 GO:0031072 heat shock protein binding(GO:0031072)
0.0 0.6 GO:0030145 manganese ion binding(GO:0030145)
0.0 0.2 GO:0003785 actin monomer binding(GO:0003785)
0.0 0.1 GO:0004966 galanin receptor activity(GO:0004966)
0.0 0.5 GO:0004693 cyclin-dependent protein serine/threonine kinase activity(GO:0004693) cyclin-dependent protein kinase activity(GO:0097472)
0.0 0.1 GO:0016615 malate dehydrogenase activity(GO:0016615)
0.0 0.1 GO:0008517 folic acid transporter activity(GO:0008517)
0.0 0.6 GO:0018024 histone-lysine N-methyltransferase activity(GO:0018024)
0.0 0.1 GO:0005021 vascular endothelial growth factor-activated receptor activity(GO:0005021)
0.0 0.4 GO:0008173 RNA methyltransferase activity(GO:0008173)
0.0 0.0 GO:0004706 JUN kinase kinase kinase activity(GO:0004706)
0.0 0.1 GO:0050786 RAGE receptor binding(GO:0050786)
0.0 0.1 GO:0047184 1-acylglycerophosphocholine O-acyltransferase activity(GO:0047184)
0.0 0.0 GO:0070215 obsolete MDM2 binding(GO:0070215)
0.0 0.1 GO:0004340 glucokinase activity(GO:0004340)
0.0 0.0 GO:0015183 L-aspartate transmembrane transporter activity(GO:0015183)
0.0 0.1 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.0 0.0 GO:0034713 type I transforming growth factor beta receptor binding(GO:0034713)
0.0 0.4 GO:0016831 carboxy-lyase activity(GO:0016831)
0.0 0.1 GO:0001727 lipid kinase activity(GO:0001727)
0.0 0.3 GO:0004890 GABA-A receptor activity(GO:0004890)
0.0 0.1 GO:0015185 gamma-aminobutyric acid transmembrane transporter activity(GO:0015185)
0.0 0.1 GO:0017154 semaphorin receptor activity(GO:0017154)
0.0 0.1 GO:0032452 histone demethylase activity(GO:0032452)
0.0 0.0 GO:0008545 JUN kinase kinase activity(GO:0008545)
0.0 0.1 GO:0015307 drug:proton antiporter activity(GO:0015307)
0.0 0.1 GO:0005375 copper ion transmembrane transporter activity(GO:0005375)
0.0 0.1 GO:0005110 frizzled-2 binding(GO:0005110)
0.0 0.0 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.0 0.1 GO:0008499 UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity(GO:0008499)
0.0 0.1 GO:0032041 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041) histone deacetylase activity (H4-K16 specific)(GO:0034739) NAD-dependent histone deacetylase activity (H4-K16 specific)(GO:0046970)
0.0 0.0 GO:0008900 hydrogen:potassium-exchanging ATPase activity(GO:0008900)
0.0 0.0 GO:0042577 lipid phosphatase activity(GO:0042577)
0.0 0.1 GO:0017075 syntaxin-1 binding(GO:0017075)
0.0 0.1 GO:0016494 C-X-C chemokine receptor activity(GO:0016494)
0.0 0.4 GO:0016504 peptidase activator activity(GO:0016504)
0.0 0.1 GO:0008469 histone-arginine N-methyltransferase activity(GO:0008469)
0.0 0.3 GO:0016628 oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor(GO:0016628)
0.0 0.2 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0 0.3 GO:0046332 SMAD binding(GO:0046332)
0.0 0.1 GO:0004028 3-chloroallyl aldehyde dehydrogenase activity(GO:0004028)
0.0 0.1 GO:0098988 adenylate cyclase inhibiting G-protein coupled glutamate receptor activity(GO:0001640) G-protein coupled glutamate receptor activity(GO:0098988)
0.0 0.0 GO:0016004 phospholipase activator activity(GO:0016004)
0.0 1.6 GO:0003714 transcription corepressor activity(GO:0003714)
0.0 0.1 GO:0016783 sulfurtransferase activity(GO:0016783)
0.0 0.0 GO:0015226 amino-acid betaine transmembrane transporter activity(GO:0015199) carnitine transmembrane transporter activity(GO:0015226)
0.0 0.7 GO:0044389 ubiquitin protein ligase binding(GO:0031625) ubiquitin-like protein ligase binding(GO:0044389)
0.0 0.5 GO:0016811 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides(GO:0016811)
0.0 0.1 GO:0050733 RS domain binding(GO:0050733)
0.0 0.0 GO:0031127 galactoside 2-alpha-L-fucosyltransferase activity(GO:0008107) alpha-(1,2)-fucosyltransferase activity(GO:0031127)
0.0 0.1 GO:0032393 MHC class I receptor activity(GO:0032393)
0.0 0.1 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.0 0.1 GO:0008417 fucosyltransferase activity(GO:0008417)
0.0 0.0 GO:0033300 dehydroascorbic acid transporter activity(GO:0033300)
0.0 0.1 GO:0042162 telomeric DNA binding(GO:0042162)
0.0 0.1 GO:0043548 phosphatidylinositol 3-kinase binding(GO:0043548)
0.0 0.0 GO:0031545 procollagen-proline 4-dioxygenase activity(GO:0004656) peptidyl-proline 4-dioxygenase activity(GO:0031545)
0.0 0.0 GO:0004142 diacylglycerol cholinephosphotransferase activity(GO:0004142)
0.0 0.2 GO:0031418 L-ascorbic acid binding(GO:0031418)
0.0 0.2 GO:0000030 mannosyltransferase activity(GO:0000030)
0.0 0.2 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.0 0.3 GO:0003724 RNA helicase activity(GO:0003724)
0.0 0.0 GO:0008384 IkappaB kinase activity(GO:0008384)
0.0 0.1 GO:0004602 glutathione peroxidase activity(GO:0004602)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.1 PID ERBB4 PATHWAY ErbB4 signaling events
0.0 0.1 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.0 0.1 PID WNT NONCANONICAL PATHWAY Noncanonical Wnt signaling pathway
0.0 0.9 PID FOXM1 PATHWAY FOXM1 transcription factor network
0.0 0.3 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.0 0.4 PID MAPK TRK PATHWAY Trk receptor signaling mediated by the MAPK pathway
0.0 0.2 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0 1.4 PID AR PATHWAY Coregulation of Androgen receptor activity
0.0 0.5 PID NFKAPPAB CANONICAL PATHWAY Canonical NF-kappaB pathway
0.0 0.6 PID ALK1 PATHWAY ALK1 signaling events
0.0 0.4 SA B CELL RECEPTOR COMPLEXES Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.0 1.1 PID TRKR PATHWAY Neurotrophic factor-mediated Trk receptor signaling
0.0 0.8 PID RB 1PATHWAY Regulation of retinoblastoma protein
0.0 0.4 PID NECTIN PATHWAY Nectin adhesion pathway
0.0 0.3 PID S1P S1P2 PATHWAY S1P2 pathway
0.0 0.3 PID AURORA A PATHWAY Aurora A signaling
0.0 0.1 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.0 0.7 PID FANCONI PATHWAY Fanconi anemia pathway
0.0 0.3 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.0 0.1 PID S1P S1P1 PATHWAY S1P1 pathway
0.0 0.1 PID TCR JNK PATHWAY JNK signaling in the CD4+ TCR pathway
0.0 0.2 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.0 0.1 ST TYPE I INTERFERON PATHWAY Type I Interferon (alpha/beta IFN) Pathway
0.0 0.5 PID RHOA REG PATHWAY Regulation of RhoA activity
0.0 0.3 PID HIF2PATHWAY HIF-2-alpha transcription factor network
0.0 0.3 PID WNT SIGNALING PATHWAY Wnt signaling network
0.0 0.1 PID IGF1 PATHWAY IGF1 pathway
0.0 0.2 PID RETINOIC ACID PATHWAY Retinoic acid receptors-mediated signaling
0.0 0.7 PID MYC ACTIV PATHWAY Validated targets of C-MYC transcriptional activation
0.0 0.6 PID CMYB PATHWAY C-MYB transcription factor network
0.0 0.1 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0 0.2 PID INTEGRIN1 PATHWAY Beta1 integrin cell surface interactions
0.0 0.5 PID P73PATHWAY p73 transcription factor network
0.0 0.2 PID NCADHERIN PATHWAY N-cadherin signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.1 REACTOME REMOVAL OF THE FLAP INTERMEDIATE FROM THE C STRAND Genes involved in Removal of the Flap Intermediate from the C-strand
0.1 0.6 REACTOME P75NTR RECRUITS SIGNALLING COMPLEXES Genes involved in p75NTR recruits signalling complexes
0.0 0.5 REACTOME ROLE OF DCC IN REGULATING APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.0 0.8 REACTOME CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
0.0 0.2 REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.0 0.6 REACTOME HYALURONAN METABOLISM Genes involved in Hyaluronan metabolism
0.0 1.1 REACTOME ACTIVATION OF THE PRE REPLICATIVE COMPLEX Genes involved in Activation of the pre-replicative complex
0.0 0.9 REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.0 0.2 REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS Genes involved in Membrane binding and targetting of GAG proteins
0.0 0.4 REACTOME P38MAPK EVENTS Genes involved in p38MAPK events
0.0 0.3 REACTOME G1 S SPECIFIC TRANSCRIPTION Genes involved in G1/S-Specific Transcription
0.0 0.3 REACTOME DOPAMINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Dopamine Neurotransmitter Release Cycle
0.0 0.2 REACTOME PECAM1 INTERACTIONS Genes involved in PECAM1 interactions
0.0 1.0 REACTOME MRNA 3 END PROCESSING Genes involved in mRNA 3'-end processing
0.0 0.4 REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.0 1.3 REACTOME PACKAGING OF TELOMERE ENDS Genes involved in Packaging Of Telomere Ends
0.0 0.3 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
0.0 0.2 REACTOME PLATELET SENSITIZATION BY LDL Genes involved in Platelet sensitization by LDL
0.0 0.0 REACTOME CYCLIN E ASSOCIATED EVENTS DURING G1 S TRANSITION Genes involved in Cyclin E associated events during G1/S transition
0.0 0.1 REACTOME APC CDC20 MEDIATED DEGRADATION OF NEK2A Genes involved in APC-Cdc20 mediated degradation of Nek2A
0.0 0.5 REACTOME FORMATION OF TUBULIN FOLDING INTERMEDIATES BY CCT TRIC Genes involved in Formation of tubulin folding intermediates by CCT/TriC
0.0 0.1 REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY Genes involved in Regulation of the Fanconi anemia pathway
0.0 0.4 REACTOME MEIOTIC SYNAPSIS Genes involved in Meiotic Synapsis
0.0 0.3 REACTOME ACYL CHAIN REMODELLING OF PI Genes involved in Acyl chain remodelling of PI
0.0 0.5 REACTOME G1 PHASE Genes involved in G1 Phase
0.0 0.2 REACTOME PURINE CATABOLISM Genes involved in Purine catabolism
0.0 0.1 REACTOME ACYL CHAIN REMODELLING OF PG Genes involved in Acyl chain remodelling of PG
0.0 0.4 REACTOME NEP NS2 INTERACTS WITH THE CELLULAR EXPORT MACHINERY Genes involved in NEP/NS2 Interacts with the Cellular Export Machinery
0.0 0.1 REACTOME IRAK1 RECRUITS IKK COMPLEX Genes involved in IRAK1 recruits IKK complex
0.0 0.3 REACTOME DOUBLE STRAND BREAK REPAIR Genes involved in Double-Strand Break Repair
0.0 0.1 REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES Genes involved in Recruitment of NuMA to mitotic centrosomes
0.0 0.3 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0 0.2 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.0 0.3 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.0 4.7 REACTOME GENERIC TRANSCRIPTION PATHWAY Genes involved in Generic Transcription Pathway
0.0 0.3 REACTOME MITOCHONDRIAL TRNA AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
0.0 0.3 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.0 0.4 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor
0.0 0.4 REACTOME MEIOSIS Genes involved in Meiosis
0.0 0.3 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.0 0.0 REACTOME RETROGRADE NEUROTROPHIN SIGNALLING Genes involved in Retrograde neurotrophin signalling
0.0 0.1 REACTOME AKT PHOSPHORYLATES TARGETS IN THE CYTOSOL Genes involved in AKT phosphorylates targets in the cytosol
0.0 0.4 REACTOME RECYCLING PATHWAY OF L1 Genes involved in Recycling pathway of L1
0.0 0.1 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.0 0.2 REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.0 0.1 REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Glutamate Neurotransmitter Release Cycle
0.0 0.2 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.0 0.1 REACTOME GASTRIN CREB SIGNALLING PATHWAY VIA PKC AND MAPK Genes involved in Gastrin-CREB signalling pathway via PKC and MAPK
0.0 0.2 REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.0 0.2 REACTOME PEROXISOMAL LIPID METABOLISM Genes involved in Peroxisomal lipid metabolism
0.0 0.2 REACTOME RNA POL III TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase III Transcription Termination
0.0 0.2 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.0 0.3 REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
0.0 0.1 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.0 0.7 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.0 0.3 REACTOME TRANSFERRIN ENDOCYTOSIS AND RECYCLING Genes involved in Transferrin endocytosis and recycling
0.0 0.1 REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
0.0 0.2 REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.0 0.1 REACTOME G0 AND EARLY G1 Genes involved in G0 and Early G1
0.0 0.2 REACTOME CGMP EFFECTS Genes involved in cGMP effects