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ENCODE: H3K4me1 ChIP-Seq of primary human cells

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CREMA is a free online tool that recognizes most important transcription factors that change the chromatin state across different samples.

Results for OLIG1

Z-value: 0.97

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Transcription factors associated with OLIG1

Gene Symbol	Gene ID	Gene Info
OLIG1 Ensembl NCBI GeneCards UniProt	ENSG00000184221.8	OLIG1

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE	Gene	Distance	Association probability	Pearson corr. coef.	P-value	Plot
OLIG1	chr21_34423143_34423294	19232	0.155625	0.67	4.6e-02	Click!
OLIG1	chr21_34437387_34437538	4988	0.191289	0.48	1.9e-01	Click!
OLIG1	chr21_34426674_34426825	15701	0.161762	0.46	2.2e-01	Click!
OLIG1	chr21_34432161_34432312	10214	0.171425	0.40	2.8e-01	Click!
OLIG1	chr21_34428906_34429057	13469	0.165550	-0.37	3.3e-01	Click!

Activity of the OLIG1 motif across conditions

Conditions sorted by the z-value of the OLIG1 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE)	Target Score	Top associated gene	Gene Info	Distance of CRE to TSS	CRE/Gene association probability
chr6_45441105_45441513	0.44	RUNX2	runt-related transcription factor 2	51087	0.15
chr14_61088518_61088669	0.43	ENSG00000253014	.	14808	0.2
chr8_79038354_79038505	0.43	ENSG00000252935	.	272428	0.02
chr8_77493773_77493963	0.38	RP11-115I9.1		2288	0.38
chr14_52595160_52595311	0.33	NID2	nidogen 2 (osteonidogen)	59523	0.13
chr17_53195275_53195426	0.31	STXBP4	syntaxin binding protein 4	118173	0.06
chr12_88794527_88794678	0.30	ENSG00000199245	.	29617	0.25
chr22_27241105_27241256	0.30	ENSG00000200443	.	190670	0.03
chr15_49733509_49733731	0.30	FGF7	fibroblast growth factor 7	18163	0.22
chr10_6962342_6962556	0.29	PRKCQ	protein kinase C, theta	340186	0.01
chr17_72509303_72509476	0.29	CD300LB	CD300 molecule-like family member b	18216	0.13
chr3_124037286_124037437	0.29	KALRN	kalirin, RhoGEF kinase	15913	0.27
chr18_25674941_25675092	0.29	CDH2	cadherin 2, type 1, N-cadherin (neuronal)	2177	0.48
chr11_120419512_120419663	0.29	GRIK4	glutamate receptor, ionotropic, kainate 4	15556	0.22
chr7_74030628_74030897	0.29	GTF2I	general transcription factor IIi	41249	0.14
chr13_107132958_107133109	0.29	EFNB2	ephrin-B2	54429	0.16
chr12_111899946_111900097	0.29	ATXN2	ataxin 2	6105	0.19
chr1_183008809_183008996	0.28	LAMC1	laminin, gamma 1 (formerly LAMB2)	16307	0.2
chr3_182849252_182849528	0.28	MCCC1	methylcrotonoyl-CoA carboxylase 1 (alpha)	15527	0.2
chr15_39048258_39048409	0.28	C15orf53	chromosome 15 open reading frame 53	59534	0.15
chr6_16742396_16742915	0.28	RP1-151F17.1		18714	0.23
chr18_48737477_48737687	0.28	MEX3C	mex-3 RNA binding family member C	13892	0.25
chr14_33868576_33868727	0.28	NPAS3	neuronal PAS domain protein 3	184133	0.03
chr7_40638110_40638340	0.27	AC004988.1		51698	0.18
chr8_96022639_96022790	0.27	NDUFAF6	NADH dehydrogenase (ubiquinone) complex I, assembly factor 6	14500	0.16
chr13_80573885_80574036	0.27	SPRY2	sprouty homolog 2 (Drosophila)	339834	0.01
chr1_186952299_186952611	0.26	PLA2G4A	phospholipase A2, group IVA (cytosolic, calcium-dependent)	154333	0.04
chr8_70410075_70410226	0.26	SULF1	sulfatase 1	5122	0.34
chr2_136577229_136577614	0.26	AC011893.3		340	0.86
chr1_88306061_88306212	0.26	ENSG00000199318	.	387080	0.01
chr10_80870394_80870545	0.26	ZMIZ1	zinc finger, MIZ-type containing 1	41677	0.18
chr17_57893390_57893541	0.26	ENSG00000199004	.	25162	0.12
chr10_77373684_77373835	0.26	RP11-310J24.3		28475	0.2
chr1_33847536_33847688	0.26	PHC2	polyhomeotic homolog 2 (Drosophila)	6418	0.16
chr2_64016844_64016995	0.26	UGP2	UDP-glucose pyrophosphorylase 2	51155	0.15
chr1_167891192_167891343	0.26	ADCY10	adenylate cyclase 10 (soluble)	7814	0.18
chr2_187752008_187752159	0.25	ZSWIM2	zinc finger, SWIM-type containing 2	38186	0.21
chr9_36053898_36054049	0.25	RECK	reversion-inducing-cysteine-rich protein with kazal motifs	17543	0.19
chr12_55372614_55372982	0.25	TESPA1	thymocyte expressed, positive selection associated 1	2824	0.31
chr8_117862426_117862577	0.25	RAD21	RAD21 homolog (S. pombe)	779	0.63
chr10_108791594_108791745	0.25	ENSG00000200626	.	61890	0.16
chr12_25098274_25098425	0.25	BCAT1	branched chain amino-acid transaminase 1, cytosolic	3628	0.21
chr4_141085920_141086071	0.25	MAML3	mastermind-like 3 (Drosophila)	10657	0.23
chr13_28630001_28630175	0.24	FLT3	fms-related tyrosine kinase 3	44619	0.12
chr2_45358656_45358834	0.24	SIX2	SIX homeobox 2	122176	0.06
chr9_109046284_109046435	0.24	ENSG00000200131	.	395899	0.01
chr1_119532975_119533248	0.24	TBX15	T-box 15	932	0.68
chr2_25222989_25223140	0.24	ENSG00000207069	.	8751	0.14
chr9_125797038_125797189	0.24	GPR21	G protein-coupled receptor 21	307	0.84
chr16_73096760_73096911	0.24	ZFHX3	zinc finger homeobox 3	3238	0.3
chr3_71349635_71349895	0.23	FOXP1	forkhead box P1	4146	0.29
chr4_16031071_16031222	0.23	ENSG00000251758	.	20736	0.19
chr6_152472602_152472908	0.23	SYNE1	spectrin repeat containing, nuclear envelope 1	16731	0.29
chr7_83737037_83737188	0.23	SEMA3A	sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A	87105	0.11
chr14_67485209_67485360	0.23	RP11-862P13.1		48751	0.17
chr1_197437825_197437976	0.23	RP11-75C23.1		21301	0.21
chr2_58957035_58957186	0.23	FANCL	Fanconi anemia, complementation group L	488603	0.01
chr12_26624053_26624388	0.23	ENSG00000212549	.	97554	0.07
chr22_29601016_29601167	0.23	EMID1	EMI domain containing 1	749	0.58
chr10_93870631_93870837	0.23	ENSG00000252993	.	34735	0.16
chr3_175075659_175075810	0.23	ENSG00000264974	.	11595	0.25
chr6_151996440_151996591	0.23	ESR1	estrogen receptor 1	15116	0.24
chr12_89938377_89938528	0.23	RP11-981P6.1		16454	0.12
chr10_22753661_22753812	0.23	RP11-301N24.3		103635	0.06
chr16_27541647_27541798	0.23	GTF3C1	general transcription factor IIIC, polypeptide 1, alpha 220kDa	19505	0.18
chr2_145219345_145219496	0.23	ZEB2	zinc finger E-box binding homeobox 2	31283	0.22
chr3_18252648_18252799	0.22	RP11-158G18.1		198404	0.03
chr8_53206465_53206616	0.22	ST18	suppression of tumorigenicity 18 (breast carcinoma) (zinc finger protein)	45454	0.18
chr5_31471142_31471293	0.22	ENSG00000206682	.	34574	0.17
chr11_132491663_132491814	0.22	ENSG00000252703	.	96035	0.09
chr12_42841049_42841316	0.22	ENSG00000207142	.	7340	0.16
chr1_235796573_235796724	0.22	GNG4	guanine nucleotide binding protein (G protein), gamma 4	16645	0.25
chr3_178046471_178046622	0.22	KCNMB2	potassium large conductance calcium-activated channel, subfamily M, beta member 2	55826	0.15
chr11_12236506_12236657	0.22	RP11-265D17.2		48139	0.13
chr1_92783230_92783381	0.22	GLMN	glomulin, FKBP associated protein	18761	0.18
chr5_121409232_121409442	0.22	LOX	lysyl oxidase	4643	0.26
chr10_120766900_120767051	0.22	ENSG00000215925	.	1673	0.29
chr20_36712631_36712782	0.22	ENSG00000264767	.	14396	0.16
chr6_44072950_44073111	0.22	TMEM63B	transmembrane protein 63B	21621	0.13
chr16_73225658_73225809	0.21	C16orf47	chromosome 16 open reading frame 47	47387	0.18
chr16_49641718_49641869	0.21	ZNF423	zinc finger protein 423	32970	0.21
chr13_53002385_53002572	0.21	THSD1	thrombospondin, type I, domain containing 1	21849	0.15
chr12_7709220_7709371	0.21	CD163	CD163 molecule	52806	0.12
chr4_157466044_157466305	0.21	RP11-171N4.2	Uncharacterized protein	97285	0.08
chr4_10702881_10703032	0.21	CLNK	cytokine-dependent hematopoietic cell linker	16467	0.3
chr10_112634404_112634566	0.21	PDCD4-AS1	PDCD4 antisense RNA 1	2494	0.2
chr12_63255377_63255568	0.21	ENSG00000200296	.	10791	0.25
chr16_68826742_68826986	0.21	RP11-354M1.2		30565	0.13
chr7_123365803_123366094	0.21	WASL	Wiskott-Aldrich syndrome-like	23173	0.16
chr6_39298603_39298754	0.21	KCNK16	potassium channel, subfamily K, member 16	7934	0.23
chr4_134079421_134079572	0.21	PCDH10	protocadherin 10	9026	0.34
chr2_36470934_36471243	0.21	CRIM1	cysteine rich transmembrane BMP regulator 1 (chordin-like)	111981	0.07
chr3_19232062_19232441	0.21	KCNH8	potassium voltage-gated channel, subfamily H (eag-related), member 8	42305	0.21
chr2_46119733_46119914	0.21	PRKCE	protein kinase C, epsilon	108218	0.07
chr6_136550393_136550544	0.21	RP13-143G15.4		3735	0.24
chr4_24804357_24804508	0.21	SOD3	superoxide dismutase 3, extracellular	7347	0.3
chr16_31407759_31407910	0.21	ITGAD	integrin, alpha D	3201	0.14
chr9_93954479_93954703	0.21	AUH	AU RNA binding protein/enoyl-CoA hydratase	169586	0.04
chr3_129311162_129311355	0.21	ENSG00000239437	.	1066	0.46
chrX_38373794_38374003	0.21	TSPAN7	tetraspanin 7	46725	0.17
chr2_152774383_152774672	0.21	CACNB4	calcium channel, voltage-dependent, beta 4 subunit	53975	0.16
chr1_154453570_154453852	0.21	RP11-350G8.9		1223	0.34
chr2_58926103_58926452	0.21	FANCL	Fanconi anemia, complementation group L	457770	0.01
chr11_17461071_17461222	0.21	ABCC8	ATP-binding cassette, sub-family C (CFTR/MRP), member 8	35061	0.14
chr6_111550909_111551060	0.21	RP11-428F8.2		29253	0.14
chr6_112167438_112167589	0.21	FYN	FYN oncogene related to SRC, FGR, YES	305	0.94
chr22_29218726_29218929	0.20	CTA-292E10.6		4508	0.17
chr7_28520558_28520791	0.20	CREB5	cAMP responsive element binding protein 5	10074	0.32
chr12_62931646_62931797	0.20	ENSG00000202034	.	7738	0.19
chr7_21904811_21904962	0.20	DNAH11	dynein, axonemal, heavy chain 11	14106	0.26
chr5_163631145_163631296	0.20	CTC-340A15.2		92482	0.1
chr9_98208297_98208448	0.20	PTCH1	patched 1	34395	0.16
chr8_93021696_93021950	0.20	RUNX1T1	runt-related transcription factor 1; translocated to, 1 (cyclin D-related)	7768	0.28
chr2_24554221_24554372	0.20	ITSN2	intersectin 2	28882	0.18
chr7_140399312_140399463	0.20	NDUFB2	NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 2, 8kDa	2258	0.21
chr8_118709861_118710368	0.20	MED30	mediator complex subunit 30	177042	0.03
chr7_130032789_130032940	0.20	CPA1	carboxypeptidase A1 (pancreatic)	11930	0.13
chr14_106493778_106493929	0.20	IGHV2-5	immunoglobulin heavy variable 2-5	744	0.3
chr6_25222668_25222819	0.20	ENSG00000264238	.	19262	0.15
chr12_2211310_2211461	0.20	CACNA1C	calcium channel, voltage-dependent, L type, alpha 1C subunit	48656	0.12
chr6_85355078_85355252	0.20	RP11-132M7.3		43978	0.2
chr6_149200106_149200257	0.20	RP11-162J8.2		85639	0.1
chr15_57512281_57512689	0.20	TCF12	transcription factor 12	821	0.73
chr6_55915532_55915683	0.20	COL21A1	collagen, type XXI, alpha 1	27295	0.26
chr2_144988608_144988759	0.20	GTDC1	glycosyltransferase-like domain containing 1	4621	0.35
chr3_10341032_10341183	0.20	GHRL	ghrelin/obestatin prepropeptide	6476	0.12
chr3_27508997_27509174	0.20	SLC4A7	solute carrier family 4, sodium bicarbonate cotransporter, member 7	10840	0.21
chr7_127526528_127526679	0.20	SND1	staphylococcal nuclease and tudor domain containing 1	1362	0.57
chr20_24434769_24434920	0.20	SYNDIG1	synapse differentiation inducing 1	14991	0.3
chr7_113437122_113437340	0.19	PPP1R3A	protein phosphatase 1, regulatory subunit 3A	121889	0.06
chr11_109983787_109983938	0.19	ZC3H12C	zinc finger CCCH-type containing 12C	17867	0.29
chr1_66071920_66072071	0.19	ENSG00000238931	.	34763	0.18
chr10_130826174_130826462	0.19	MGMT	O-6-methylguanine-DNA methyltransferase	439130	0.01
chr18_46603297_46603448	0.19	DYM	dymeclin	20491	0.16
chr2_167999915_168000066	0.19	XIRP2-AS1	XIRP2 antisense RNA 1	2525	0.39
chr1_208081697_208081872	0.19	CD34	CD34 molecule	2677	0.4
chr17_32713645_32713796	0.19	CCL1	chemokine (C-C motif) ligand 1	23470	0.16
chr16_46746695_46746902	0.19	ORC6	origin recognition complex, subunit 6	22100	0.15
chr5_164787828_164787979	0.19	ENSG00000252794	.	248543	0.02
chr1_196578665_196578816	0.19	KCNT2	potassium channel, subfamily T, member 2	385	0.88
chr17_42345228_42345379	0.19	SLC4A1	solute carrier family 4 (anion exchanger), member 1 (Diego blood group)	206	0.85
chr8_103441950_103442101	0.19	ENSG00000221387	.	8600	0.19
chr3_34303548_34303699	0.19	PDCD6IP	programmed cell death 6 interacting protein	463508	0.01
chr7_18593145_18593296	0.19	HDAC9	histone deacetylase 9	44284	0.2
chr4_80253296_80253447	0.19	NAA11	N(alpha)-acetyltransferase 11, NatA catalytic subunit	6167	0.26
chr2_27111401_27111621	0.19	DPYSL5	dihydropyrimidinase-like 5	40135	0.12
chr13_67622472_67622645	0.19	PCDH9-AS4	PCDH9 antisense RNA 4	57540	0.15
chr11_40111001_40111152	0.19	LRRC4C	leucine rich repeat containing 4C	152357	0.04
chr18_22761130_22761281	0.19	ZNF521	zinc finger protein 521	43548	0.21
chr3_45127227_45127378	0.19	ENSG00000252410	.	51222	0.11
chr1_96432200_96432351	0.19	RP11-147C23.1	Uncharacterized protein	25270	0.25
chr8_104154351_104154502	0.19	C8orf56	chromosome 8 open reading frame 56	723	0.48
chr1_183548346_183548500	0.19	NCF2	neutrophil cytosolic factor 2	10063	0.2
chr17_40473474_40473753	0.19	STAT5A	signal transducer and activator of transcription 5A	15425	0.12
chr17_74842688_74842839	0.19	MGAT5B	mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase, isozyme B	21775	0.16
chr1_54842092_54842291	0.19	SSBP3	single stranded DNA binding protein 3	28986	0.18
chr3_193974112_193974263	0.19	CPN2	carboxypeptidase N, polypeptide 2	97860	0.06
chr2_182309270_182309421	0.19	ITGA4	integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor)	12589	0.29
chr2_9768582_9768942	0.19	YWHAQ	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta	1983	0.33
chr3_119376480_119376631	0.19	POPDC2	popeye domain containing 2	2882	0.22
chr2_173116297_173116471	0.19	ENSG00000238572	.	95536	0.08
chr3_186255293_186255456	0.19	CRYGS	crystallin, gamma S	6866	0.18
chr1_41452601_41452752	0.19	CTPS1	CTP synthase 1	3843	0.27
chr10_30306295_30306795	0.19	KIAA1462	KIAA1462	41908	0.21
chr2_54659315_54659466	0.19	SPTBN1	spectrin, beta, non-erythrocytic 1	24032	0.22
chr18_22802497_22802648	0.19	ZNF521	zinc finger protein 521	2181	0.45
chr5_179520901_179521052	0.19	RNF130	ring finger protein 130	21858	0.18
chr11_112892766_112892917	0.19	ENSG00000238998	.	44766	0.15
chr4_151200956_151201107	0.19	LRBA	LPS-responsive vesicle trafficking, beach and anchor containing	22832	0.25
chr14_24793732_24793883	0.18	ADCY4	adenylate cyclase 4	4867	0.07
chr15_32773405_32773592	0.18	AC135983.2	Protein LOC100996413	1324	0.33
chr3_123239806_123239957	0.18	PTPLB	protein tyrosine phosphatase-like (proline instead of catalytic arginine), member b	20341	0.21
chr2_187620280_187620431	0.18	AC017101.10		60341	0.12
chr4_53876869_53877020	0.18	RP11-752D24.2		65088	0.13
chr6_147488002_147488153	0.18	STXBP5-AS1	STXBP5 antisense RNA 1	34955	0.2
chr3_123600718_123600990	0.18	MYLK	myosin light chain kinase	2295	0.36
chr18_20274417_20274568	0.18	RP11-370A5.1		37036	0.17
chr11_37653272_37653423	0.18	ENSG00000251838	.	70423	0.14
chr4_83932650_83933419	0.18	LIN54	lin-54 homolog (C. elegans)	1006	0.49
chr7_143112539_143112690	0.18	EPHA1	EPH receptor A1	6629	0.12
chr1_208060057_208060208	0.18	CD34	CD34 molecule	3705	0.34
chr6_90928849_90929340	0.18	BACH2	BTB and CNC homology 1, basic leucine zipper transcription factor 2	77367	0.1
chr9_113747428_113747579	0.18	LPAR1	lysophosphatidic acid receptor 1	14217	0.23
chr8_30354542_30354693	0.18	RBPMS	RNA binding protein with multiple splicing	54484	0.14
chr3_159666454_159666617	0.18	IL12A	interleukin 12A (natural killer cell stimulatory factor 1, cytotoxic lymphocyte maturation factor 1, p35)	40002	0.15
chr5_139041967_139042236	0.18	CXXC5	CXXC finger protein 5	2961	0.29
chr3_87844700_87844851	0.18	ENSG00000200703	.	52976	0.17
chr8_16425022_16425173	0.18	MSR1	macrophage scavenger receptor 1	226	0.97
chr12_125340762_125340972	0.18	SCARB1	scavenger receptor class B, member 1	7462	0.22
chr3_149096434_149096694	0.18	TM4SF1-AS1	TM4SF1 antisense RNA 1	558	0.59
chr13_105628919_105629118	0.18	DAOA	D-amino acid oxidase activator	489574	0.01
chr2_33822486_33823292	0.18	FAM98A	family with sequence similarity 98, member A	1455	0.5
chr3_124380372_124380523	0.18	KALRN	kalirin, RhoGEF kinase	15740	0.18
chr6_131576385_131576768	0.18	AKAP7	A kinase (PRKA) anchor protein 7	5006	0.34
chr6_37485114_37485476	0.18	CCDC167	coiled-coil domain containing 167	17597	0.19
chr2_103511305_103511456	0.18	TMEM182	transmembrane protein 182	132908	0.05
chr3_124340494_124340645	0.18	KALRN	kalirin, RhoGEF kinase	15375	0.23
chr11_73231354_73231697	0.18	FAM168A	family with sequence similarity 168, member A	77618	0.08
chr18_26797335_26797486	0.18	ENSG00000212085	.	20918	0.28
chr2_144987675_144987826	0.18	GTDC1	glycosyltransferase-like domain containing 1	5554	0.34

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of OLIG1

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.4	GO:0010886	positive regulation of cholesterol storage(GO:0010886)
0.1	0.2	GO:0030202	heparin metabolic process(GO:0030202)
0.1	0.3	GO:0031641	regulation of myelination(GO:0031641)
0.0	0.1	GO:0046121	deoxyribonucleoside catabolic process(GO:0046121)
0.0	0.2	GO:0060665	regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling(GO:0060665)
0.0	0.1	GO:0031223	auditory behavior(GO:0031223)
0.0	0.3	GO:0006198	cAMP catabolic process(GO:0006198)
0.0	0.1	GO:0051451	myoblast migration(GO:0051451)
0.0	0.1	GO:0045627	positive regulation of T-helper 1 cell differentiation(GO:0045627)
0.0	0.2	GO:0001757	somite specification(GO:0001757)
0.0	0.1	GO:0000103	sulfate assimilation(GO:0000103)
0.0	0.1	GO:0048791	calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.0	0.2	GO:0002634	regulation of germinal center formation(GO:0002634)
0.0	0.2	GO:0071168	protein localization to chromatin(GO:0071168)
0.0	0.1	GO:0034501	protein localization to kinetochore(GO:0034501)
0.0	0.1	GO:0051497	negative regulation of stress fiber assembly(GO:0051497)
0.0	0.1	GO:0046642	negative regulation of alpha-beta T cell proliferation(GO:0046642)
0.0	0.2	GO:0034755	iron ion transmembrane transport(GO:0034755)
0.0	0.1	GO:0060028	convergent extension involved in axis elongation(GO:0060028)
0.0	0.1	GO:0070874	negative regulation of glycogen metabolic process(GO:0070874)
0.0	0.2	GO:0040015	negative regulation of multicellular organism growth(GO:0040015)
0.0	0.1	GO:0048149	behavioral response to ethanol(GO:0048149)
0.0	0.1	GO:0071277	cellular response to calcium ion(GO:0071277)
0.0	0.1	GO:0043578	nuclear matrix organization(GO:0043578) nuclear matrix anchoring at nuclear membrane(GO:0090292)
0.0	0.2	GO:0045410	positive regulation of interleukin-6 biosynthetic process(GO:0045410)
0.0	0.1	GO:0060023	soft palate development(GO:0060023)
0.0	0.1	GO:0002063	chondrocyte development(GO:0002063)
0.0	0.1	GO:0006658	phosphatidylserine metabolic process(GO:0006658)
0.0	0.0	GO:0090073	positive regulation of protein homodimerization activity(GO:0090073)
0.0	0.1	GO:0051305	chromosome movement towards spindle pole(GO:0051305)
0.0	0.1	GO:0001955	blood vessel maturation(GO:0001955)
0.0	0.1	GO:0002313	mature B cell differentiation involved in immune response(GO:0002313)
0.0	0.1	GO:0006552	leucine catabolic process(GO:0006552)
0.0	0.1	GO:0051005	negative regulation of lipoprotein lipase activity(GO:0051005)
0.0	0.1	GO:0035234	ectopic germ cell programmed cell death(GO:0035234)
0.0	0.1	GO:0070071	proton-transporting two-sector ATPase complex assembly(GO:0070071)
0.0	0.0	GO:0042637	catagen(GO:0042637)
0.0	0.1	GO:0008218	bioluminescence(GO:0008218)
0.0	0.1	GO:0060750	epithelial cell proliferation involved in mammary gland duct elongation(GO:0060750)
0.0	0.0	GO:0070254	mucus secretion(GO:0070254)
0.0	0.0	GO:0002085	inhibition of neuroepithelial cell differentiation(GO:0002085)
0.0	0.1	GO:0090162	establishment of epithelial cell polarity(GO:0090162)
0.0	0.0	GO:0071379	cellular response to prostaglandin stimulus(GO:0071379)
0.0	0.1	GO:0006930	substrate-dependent cell migration, cell extension(GO:0006930)
0.0	0.1	GO:0061030	epithelial cell differentiation involved in mammary gland alveolus development(GO:0061030)
0.0	0.1	GO:0050685	positive regulation of mRNA 3'-end processing(GO:0031442) positive regulation of mRNA processing(GO:0050685) positive regulation of mRNA metabolic process(GO:1903313)
0.0	0.1	GO:0060394	negative regulation of pathway-restricted SMAD protein phosphorylation(GO:0060394)
0.0	0.1	GO:0045662	negative regulation of myoblast differentiation(GO:0045662)
0.0	0.1	GO:0017085	response to insecticide(GO:0017085)
0.0	0.1	GO:0060666	dichotomous subdivision of terminal units involved in salivary gland branching(GO:0060666)
0.0	0.1	GO:0006663	platelet activating factor biosynthetic process(GO:0006663)
0.0	0.1	GO:0003056	regulation of vascular smooth muscle contraction(GO:0003056)
0.0	0.1	GO:0000089	mitotic metaphase(GO:0000089)
0.0	0.1	GO:0060083	smooth muscle contraction involved in micturition(GO:0060083)
0.0	0.0	GO:0033025	mast cell homeostasis(GO:0033023) mast cell apoptotic process(GO:0033024) regulation of mast cell apoptotic process(GO:0033025)
0.0	0.1	GO:0007028	cytoplasm organization(GO:0007028)
0.0	0.1	GO:0033262	regulation of nuclear cell cycle DNA replication(GO:0033262)
0.0	0.3	GO:0015701	bicarbonate transport(GO:0015701)
0.0	0.0	GO:0019049	evasion or tolerance of host defenses by virus(GO:0019049) avoidance of host defenses(GO:0044413) evasion or tolerance of host defenses(GO:0044415) avoidance of defenses of other organism involved in symbiotic interaction(GO:0051832) evasion or tolerance of defenses of other organism involved in symbiotic interaction(GO:0051834)
0.0	0.1	GO:0040037	negative regulation of fibroblast growth factor receptor signaling pathway(GO:0040037)
0.0	0.0	GO:0002679	respiratory burst involved in defense response(GO:0002679)
0.0	0.1	GO:0015760	hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760)
0.0	0.1	GO:0002423	natural killer cell mediated cytotoxicity directed against tumor cell target(GO:0002420) natural killer cell mediated immune response to tumor cell(GO:0002423) regulation of natural killer cell mediated immune response to tumor cell(GO:0002855) positive regulation of natural killer cell mediated immune response to tumor cell(GO:0002857) regulation of natural killer cell mediated cytotoxicity directed against tumor cell target(GO:0002858) positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target(GO:0002860)
0.0	0.1	GO:0002138	retinoic acid biosynthetic process(GO:0002138) diterpenoid biosynthetic process(GO:0016102)
0.0	0.1	GO:0033314	mitotic DNA replication checkpoint(GO:0033314)
0.0	0.0	GO:0060676	ureteric bud formation(GO:0060676)
0.0	0.1	GO:0051597	response to methylmercury(GO:0051597)
0.0	0.0	GO:0032413	negative regulation of ion transmembrane transporter activity(GO:0032413)
0.0	0.1	GO:0006610	ribosomal protein import into nucleus(GO:0006610)
0.0	0.0	GO:1900116	sequestering of extracellular ligand from receptor(GO:0035581) sequestering of TGFbeta in extracellular matrix(GO:0035583) protein localization to extracellular region(GO:0071692) maintenance of protein location in extracellular region(GO:0071694) extracellular regulation of signal transduction(GO:1900115) extracellular negative regulation of signal transduction(GO:1900116)
0.0	0.1	GO:0071364	cellular response to epidermal growth factor stimulus(GO:0071364)
0.0	0.1	GO:0072386	plus-end-directed vesicle transport along microtubule(GO:0072383) plus-end-directed organelle transport along microtubule(GO:0072386)
0.0	0.0	GO:0060235	lens induction in camera-type eye(GO:0060235)
0.0	0.0	GO:0001831	trophectodermal cellular morphogenesis(GO:0001831)
0.0	0.0	GO:0006922	obsolete cleavage of lamin involved in execution phase of apoptosis(GO:0006922)
0.0	0.0	GO:0006590	thyroid hormone generation(GO:0006590)
0.0	0.0	GO:0006551	leucine metabolic process(GO:0006551)
0.0	0.1	GO:0002282	microglial cell activation involved in immune response(GO:0002282)
0.0	0.1	GO:0007158	neuron cell-cell adhesion(GO:0007158)
0.0	0.0	GO:0010903	negative regulation of very-low-density lipoprotein particle remodeling(GO:0010903)
0.0	0.0	GO:0060295	regulation of cilium movement(GO:0003352) regulation of cilium beat frequency(GO:0003356) cilium movement involved in cell motility(GO:0060294) regulation of cilium movement involved in cell motility(GO:0060295) regulation of cilium beat frequency involved in ciliary motility(GO:0060296) regulation of cilium-dependent cell motility(GO:1902019)
0.0	0.1	GO:0031936	negative regulation of chromatin silencing(GO:0031936)
0.0	0.1	GO:0009313	oligosaccharide catabolic process(GO:0009313)
0.0	0.0	GO:0015014	heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.0	0.1	GO:0015840	urea transport(GO:0015840)
0.0	0.0	GO:0060831	smoothened signaling pathway involved in dorsal/ventral neural tube patterning(GO:0060831)
0.0	0.0	GO:2000095	regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000095)
0.0	0.0	GO:0006651	diacylglycerol biosynthetic process(GO:0006651)
0.0	0.0	GO:0060285	cilium-dependent cell motility(GO:0060285)
0.0	0.1	GO:0098870	neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870)
0.0	0.0	GO:0007571	age-dependent response to oxidative stress(GO:0001306) age-dependent general metabolic decline(GO:0007571)
0.0	0.0	GO:0060013	righting reflex(GO:0060013)
0.0	0.0	GO:0034371	chylomicron remodeling(GO:0034371)
0.0	0.1	GO:0016265	obsolete death(GO:0016265)
0.0	0.1	GO:0070102	interleukin-6-mediated signaling pathway(GO:0070102)
0.0	0.1	GO:0034331	cell junction maintenance(GO:0034331) cell-cell junction maintenance(GO:0045217)
0.0	0.0	GO:0010901	regulation of very-low-density lipoprotein particle remodeling(GO:0010901)
0.0	0.0	GO:0006530	asparagine catabolic process(GO:0006530) asparagine catabolic process via L-aspartate(GO:0033345)
0.0	0.1	GO:0007016	cytoskeletal anchoring at plasma membrane(GO:0007016)
0.0	0.0	GO:0032823	regulation of natural killer cell differentiation(GO:0032823) positive regulation of natural killer cell differentiation(GO:0032825)
0.0	0.1	GO:0043508	negative regulation of JUN kinase activity(GO:0043508)
0.0	0.1	GO:0019441	tryptophan catabolic process to kynurenine(GO:0019441)
0.0	0.0	GO:0001543	ovarian follicle rupture(GO:0001543)
0.0	0.1	GO:0000712	resolution of meiotic recombination intermediates(GO:0000712) meiotic chromosome separation(GO:0051307)
0.0	0.0	GO:0045989	positive regulation of striated muscle contraction(GO:0045989)
0.0	0.0	GO:0030952	establishment or maintenance of cytoskeleton polarity(GO:0030952)
0.0	0.0	GO:0017121	phospholipid scrambling(GO:0017121)
0.0	0.1	GO:0021535	cell migration in hindbrain(GO:0021535)
0.0	0.0	GO:0061299	retina vasculature development in camera-type eye(GO:0061298) retina vasculature morphogenesis in camera-type eye(GO:0061299)
0.0	0.1	GO:0046218	tryptophan catabolic process(GO:0006569) indole-containing compound catabolic process(GO:0042436) indolalkylamine catabolic process(GO:0046218)
0.0	0.1	GO:1901503	ether lipid biosynthetic process(GO:0008611) glycerol ether biosynthetic process(GO:0046504) ether biosynthetic process(GO:1901503)
0.0	0.0	GO:0042536	negative regulation of tumor necrosis factor biosynthetic process(GO:0042536)
0.0	0.1	GO:0048251	elastic fiber assembly(GO:0048251)
0.0	0.3	GO:0071804	cellular potassium ion transport(GO:0071804) potassium ion transmembrane transport(GO:0071805)
0.0	0.0	GO:0018242	protein O-linked glycosylation via serine(GO:0018242) protein O-linked glycosylation via threonine(GO:0018243)
0.0	0.2	GO:0016998	cell wall macromolecule catabolic process(GO:0016998)
0.0	0.0	GO:0071680	response to indole-3-methanol(GO:0071680) cellular response to indole-3-methanol(GO:0071681)
0.0	0.1	GO:1990748	removal of superoxide radicals(GO:0019430) cellular response to oxygen radical(GO:0071450) cellular response to superoxide(GO:0071451) cellular oxidant detoxification(GO:0098869) cellular detoxification(GO:1990748)
0.0	0.0	GO:0060219	camera-type eye photoreceptor cell differentiation(GO:0060219)
0.0	0.0	GO:0050862	positive regulation of T cell receptor signaling pathway(GO:0050862)
0.0	0.0	GO:0090136	epithelial cell-cell adhesion(GO:0090136)
0.0	0.1	GO:0046835	carbohydrate phosphorylation(GO:0046835)
0.0	0.1	GO:0043537	negative regulation of blood vessel endothelial cell migration(GO:0043537)
0.0	0.1	GO:0007263	nitric oxide mediated signal transduction(GO:0007263)
0.0	0.1	GO:0050847	progesterone receptor signaling pathway(GO:0050847)
0.0	0.2	GO:0032330	regulation of chondrocyte differentiation(GO:0032330)
0.0	0.0	GO:0015722	canalicular bile acid transport(GO:0015722)
0.0	0.0	GO:0010896	regulation of triglyceride catabolic process(GO:0010896)
0.0	0.0	GO:0043490	malate-aspartate shuttle(GO:0043490)
0.0	0.0	GO:0010837	regulation of keratinocyte proliferation(GO:0010837)
0.0	0.0	GO:0032957	inositol trisphosphate metabolic process(GO:0032957)
0.0	0.0	GO:0006654	phosphatidic acid biosynthetic process(GO:0006654)
0.0	0.0	GO:0009173	UMP biosynthetic process(GO:0006222) pyrimidine ribonucleoside monophosphate metabolic process(GO:0009173) pyrimidine ribonucleoside monophosphate biosynthetic process(GO:0009174) UMP metabolic process(GO:0046049)
0.0	0.1	GO:0007549	dosage compensation(GO:0007549)
0.0	0.1	GO:0007199	G-protein coupled receptor signaling pathway coupled to cGMP nucleotide second messenger(GO:0007199)
0.0	0.0	GO:0043615	astrocyte cell migration(GO:0043615)
0.0	0.0	GO:0018094	protein polyglycylation(GO:0018094)
0.0	0.1	GO:0007185	transmembrane receptor protein tyrosine phosphatase signaling pathway(GO:0007185)
0.0	0.0	GO:0032497	detection of lipopolysaccharide(GO:0032497)
0.0	0.1	GO:0060216	definitive hemopoiesis(GO:0060216)
0.0	0.1	GO:0032007	negative regulation of TOR signaling(GO:0032007)
0.0	0.1	GO:0007598	blood coagulation, extrinsic pathway(GO:0007598)

Gene overrepresentation in cellular component category:

Total log-likelihood	Term	Description
0.2	GO:0005916	fascia adherens(GO:0005916)
0.0	GO:0034363	intermediate-density lipoprotein particle(GO:0034363)
0.2	GO:0046581	intercellular canaliculus(GO:0046581)
0.1	GO:0000300	obsolete peripheral to membrane of membrane fraction(GO:0000300)
0.1	GO:0030934	anchoring collagen complex(GO:0030934)
0.1	GO:0005915	zonula adherens(GO:0005915)
0.1	GO:0018995	host(GO:0018995) host cell part(GO:0033643) host intracellular part(GO:0033646) intracellular region of host(GO:0043656) host cell(GO:0043657) other organism(GO:0044215) other organism cell(GO:0044216) other organism part(GO:0044217)
0.2	GO:0034362	low-density lipoprotein particle(GO:0034362)
0.2	GO:0043205	fibril(GO:0043205)
0.1	GO:0031092	platelet alpha granule membrane(GO:0031092)
0.2	GO:0031105	septin complex(GO:0031105) septin cytoskeleton(GO:0032156)
0.1	GO:0030127	COPII vesicle coat(GO:0030127)
0.2	GO:0008278	cohesin complex(GO:0008278)
0.1	GO:0034992	microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.0	GO:0060201	clathrin-sculpted acetylcholine transport vesicle(GO:0060200) clathrin-sculpted acetylcholine transport vesicle membrane(GO:0060201)
0.1	GO:0031265	CD95 death-inducing signaling complex(GO:0031265)
0.1	GO:0031332	RISC complex(GO:0016442) RNAi effector complex(GO:0031332)
0.1	GO:0099738	cell cortex region(GO:0099738)
0.0	GO:1990316	ATG1/ULK1 kinase complex(GO:1990316)
0.1	GO:0005952	cAMP-dependent protein kinase complex(GO:0005952)
0.0	GO:0031205	endoplasmic reticulum Sec complex(GO:0031205)
0.0	GO:0005896	interleukin-6 receptor complex(GO:0005896)
0.0	GO:0036126	outer dense fiber(GO:0001520) sperm flagellum(GO:0036126)
0.1	GO:0031094	platelet dense tubular network(GO:0031094)
0.0	GO:0035145	exon-exon junction complex(GO:0035145)
0.0	GO:0043260	laminin-11 complex(GO:0043260)
0.1	GO:0008328	ionotropic glutamate receptor complex(GO:0008328) neurotransmitter receptor complex(GO:0098878)
0.0	GO:0032045	guanyl-nucleotide exchange factor complex(GO:0032045)
0.1	GO:0045009	melanosome membrane(GO:0033162) chitosome(GO:0045009)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.3	GO:0000978	RNA polymerase II core promoter proximal region sequence-specific DNA binding(GO:0000978) core promoter proximal region sequence-specific DNA binding(GO:0000987) core promoter proximal region DNA binding(GO:0001159)
0.1	0.2	GO:0003680	AT DNA binding(GO:0003680)
0.1	0.2	GO:0042808	obsolete neuronal Cdc2-like kinase binding(GO:0042808)
0.1	0.2	GO:0030023	extracellular matrix constituent conferring elasticity(GO:0030023) structural molecule activity conferring elasticity(GO:0097493)
0.0	0.1	GO:0004720	protein-lysine 6-oxidase activity(GO:0004720)
0.0	0.1	GO:0070097	delta-catenin binding(GO:0070097)
0.0	0.1	GO:0004687	myosin light chain kinase activity(GO:0004687)
0.0	0.1	GO:0015204	urea transmembrane transporter activity(GO:0015204)
0.0	0.1	GO:0047756	chondroitin 4-sulfotransferase activity(GO:0047756)
0.0	0.1	GO:0005173	stem cell factor receptor binding(GO:0005173)
0.0	0.1	GO:0042910	xenobiotic-transporting ATPase activity(GO:0008559) xenobiotic transporter activity(GO:0042910)
0.0	0.2	GO:0045294	alpha-catenin binding(GO:0045294)
0.0	0.2	GO:0005381	iron ion transmembrane transporter activity(GO:0005381)
0.0	0.1	GO:0043495	protein anchor(GO:0043495)
0.0	0.1	GO:0004833	tryptophan 2,3-dioxygenase activity(GO:0004833)
0.0	0.4	GO:0030169	low-density lipoprotein particle binding(GO:0030169)
0.0	0.1	GO:0015562	efflux transmembrane transporter activity(GO:0015562)
0.0	0.1	GO:0005111	type 2 fibroblast growth factor receptor binding(GO:0005111)
0.0	0.1	GO:0005030	neurotrophin receptor activity(GO:0005030)
0.0	0.1	GO:0008475	procollagen-lysine 5-dioxygenase activity(GO:0008475)
0.0	0.2	GO:0030274	LIM domain binding(GO:0030274)
0.0	0.1	GO:0008321	Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.0	0.1	GO:0008510	sodium:bicarbonate symporter activity(GO:0008510)
0.0	0.1	GO:0071553	uridine nucleotide receptor activity(GO:0015065) G-protein coupled pyrimidinergic nucleotide receptor activity(GO:0071553)
0.0	0.1	GO:0004596	peptide alpha-N-acetyltransferase activity(GO:0004596)
0.0	0.1	GO:0004117	calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117)
0.0	0.1	GO:0005220	inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.0	0.1	GO:0052743	inositol tetrakisphosphate phosphatase activity(GO:0052743)
0.0	0.1	GO:0004656	procollagen-proline 4-dioxygenase activity(GO:0004656) peptidyl-proline 4-dioxygenase activity(GO:0031545)
0.0	0.1	GO:0017154	semaphorin receptor activity(GO:0017154)
0.0	0.1	GO:0016004	phospholipase activator activity(GO:0016004)
0.0	0.1	GO:0004597	peptide-aspartate beta-dioxygenase activity(GO:0004597)
0.0	0.1	GO:0004949	cannabinoid receptor activity(GO:0004949)
0.0	0.0	GO:0042577	lipid phosphatase activity(GO:0042577)
0.0	0.1	GO:0070653	high-density lipoprotein particle receptor binding(GO:0070653)
0.0	0.1	GO:0051371	muscle alpha-actinin binding(GO:0051371)
0.0	0.1	GO:0004784	superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
0.0	0.3	GO:0015269	calcium-activated potassium channel activity(GO:0015269)
0.0	0.0	GO:0034056	estrogen response element binding(GO:0034056)
0.0	0.0	GO:0070052	collagen V binding(GO:0070052)
0.0	0.1	GO:0016635	oxidoreductase activity, acting on the CH-CH group of donors, quinone or related compound as acceptor(GO:0016635)
0.0	0.0	GO:0016215	stearoyl-CoA 9-desaturase activity(GO:0004768) acyl-CoA desaturase activity(GO:0016215)
0.0	0.0	GO:0035005	1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.0	0.0	GO:0030151	molybdenum ion binding(GO:0030151)
0.0	0.1	GO:0005315	inorganic phosphate transmembrane transporter activity(GO:0005315)
0.0	0.0	GO:0016309	1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
0.0	0.1	GO:0016406	carnitine O-acyltransferase activity(GO:0016406)
0.0	0.1	GO:0005521	lamin binding(GO:0005521)
0.0	0.0	GO:0008331	high voltage-gated calcium channel activity(GO:0008331)
0.0	0.0	GO:0019763	immunoglobulin receptor activity(GO:0019763)
0.0	0.1	GO:0004982	N-formyl peptide receptor activity(GO:0004982)
0.0	0.0	GO:0060228	phosphatidylcholine-sterol O-acyltransferase activator activity(GO:0060228)
0.0	0.0	GO:0004800	thyroxine 5'-deiodinase activity(GO:0004800)
0.0	0.1	GO:0008191	metalloendopeptidase inhibitor activity(GO:0008191)
0.0	0.0	GO:0004939	beta-adrenergic receptor activity(GO:0004939)
0.0	0.1	GO:0030332	cyclin binding(GO:0030332)
0.0	0.0	GO:0003896	DNA primase activity(GO:0003896)
0.0	0.1	GO:0015057	thrombin receptor activity(GO:0015057)
0.0	0.1	GO:0004691	cAMP-dependent protein kinase activity(GO:0004691)
0.0	0.1	GO:0015355	secondary active monocarboxylate transmembrane transporter activity(GO:0015355)
0.0	0.0	GO:0017128	phospholipid scramblase activity(GO:0017128)
0.0	0.2	GO:0004115	3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0	0.1	GO:0070290	N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.0	0.1	GO:0016832	aldehyde-lyase activity(GO:0016832)
0.0	0.1	GO:0001619	obsolete lysosphingolipid and lysophosphatidic acid receptor activity(GO:0001619)
0.0	0.1	GO:0005138	interleukin-6 receptor binding(GO:0005138)
0.0	0.0	GO:0004157	dihydropyrimidinase activity(GO:0004157)
0.0	0.1	GO:0043274	phospholipase binding(GO:0043274)
0.0	0.1	GO:0070696	transmembrane receptor protein serine/threonine kinase binding(GO:0070696)
0.0	0.1	GO:0051019	mitogen-activated protein kinase binding(GO:0051019)
0.0	0.0	GO:0070735	protein-glycine ligase activity(GO:0070735)
0.0	0.0	GO:0003876	AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.0	0.1	GO:0015277	kainate selective glutamate receptor activity(GO:0015277)
0.0	0.0	GO:0050265	RNA uridylyltransferase activity(GO:0050265)

Gene overrepresentation in curated gene sets: canonical pathways category:

Total log-likelihood	Term	Description
0.0	PID INSULIN PATHWAY	Insulin Pathway
0.0	PID VEGFR1 PATHWAY	VEGFR1 specific signals
0.0	SIG PIP3 SIGNALING IN B LYMPHOCYTES	Genes related to PIP3 signaling in B lymphocytes
0.0	PID THROMBIN PAR1 PATHWAY	PAR1-mediated thrombin signaling events
0.0	PID PS1 PATHWAY	Presenilin action in Notch and Wnt signaling
0.1	PID LYSOPHOSPHOLIPID PATHWAY	LPA receptor mediated events
0.2	PID ARF6 DOWNSTREAM PATHWAY	Arf6 downstream pathway
0.0	PID HDAC CLASSII PATHWAY	Signaling events mediated by HDAC Class II
0.0	PID PDGFRA PATHWAY	PDGFR-alpha signaling pathway
0.1	PID CXCR4 PATHWAY	CXCR4-mediated signaling events
0.1	SA G2 AND M PHASES	Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.0	PID PI3K PLC TRK PATHWAY	Trk receptor signaling mediated by PI3K and PLC-gamma

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Total log-likelihood	Term	Description
0.0	REACTOME OPIOID SIGNALLING	Genes involved in Opioid Signalling
0.8	REACTOME MYOGENESIS	Genes involved in Myogenesis
0.0	REACTOME DOWNSTREAM SIGNALING EVENTS OF B CELL RECEPTOR BCR	Genes involved in Downstream Signaling Events Of B Cell Receptor (BCR)
0.3	REACTOME CRMPS IN SEMA3A SIGNALING	Genes involved in CRMPs in Sema3A signaling
0.2	REACTOME VEGF LIGAND RECEPTOR INTERACTIONS	Genes involved in VEGF ligand-receptor interactions
0.2	REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS	Genes involved in Ionotropic activity of Kainate Receptors
0.1	REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION	Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.1	REACTOME E2F ENABLED INHIBITION OF PRE REPLICATION COMPLEX FORMATION	Genes involved in E2F-enabled inhibition of pre-replication complex formation
0.1	REACTOME ABACAVIR TRANSPORT AND METABOLISM	Genes involved in Abacavir transport and metabolism
0.3	REACTOME DARPP 32 EVENTS	Genes involved in DARPP-32 events
0.0	REACTOME PECAM1 INTERACTIONS	Genes involved in PECAM1 interactions
0.3	REACTOME SMOOTH MUSCLE CONTRACTION	Genes involved in Smooth Muscle Contraction
0.1	REACTOME TRYPTOPHAN CATABOLISM	Genes involved in Tryptophan catabolism
0.1	REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK	Genes involved in Negative regulation of the PI3K/AKT network