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ENCODE: H3K4me1 ChIP-Seq of primary human cells
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Results for OLIG2_NEUROD1_ATOH1

Z-value: 1.07

Motif logo

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Transcription factors associated with OLIG2_NEUROD1_ATOH1

Gene Symbol Gene ID Gene Info
OLIG2
ENSG00000205927.4 oligodendrocyte transcription factor 2
NEUROD1
ENSG00000162992.3 neuronal differentiation 1
ATOH1
ENSG00000172238.3 atonal bHLH transcription factor 1

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE Gene Distance Association probability Pearson corr. coef. P-value Plot
chr4_94755891_94756042ATOH159240.2709350.581.0e-01Click!
chr4_94750213_94750368ATOH12480.9463420.481.9e-01Click!
chr4_94749649_94749800ATOH13180.9233350.383.2e-01Click!
chr4_94749842_94750092ATOH1750.9811050.343.7e-01Click!
chr4_94755666_94755817ATOH156990.2727410.333.9e-01Click!
chr2_182546095_182546262NEUROD15750.691130-0.511.6e-01Click!
chr2_182537560_182537711NEUROD179680.186963-0.511.6e-01Click!
chr2_182546333_182546484NEUROD18050.535301-0.452.3e-01Click!
chr2_182546571_182546722NEUROD110430.398476-0.432.5e-01Click!
chr2_182545549_182545700NEUROD1210.973141-0.333.9e-01Click!
chr21_34414432_34414583OLIG2162640.1670280.881.7e-03Click!
chr21_34400775_34400926OLIG226070.282370-0.732.4e-02Click!
chr21_34312598_34312749OLIG2854800.066605-0.713.1e-02Click!
chr21_34401737_34401918OLIG235840.241023-0.693.9e-02Click!
chr21_34415527_34415678OLIG2173590.1639030.694.0e-02Click!

Activity of the OLIG2_NEUROD1_ATOH1 motif across conditions

Conditions sorted by the z-value of the OLIG2_NEUROD1_ATOH1 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE) Target Score Top associated gene Gene Info Distance of CRE to TSS CRE/Gene association probability
chr1_224752371_224752739 0.81 RP11-100E13.1
51367
 0.13
chr20_47299343_47299823 0.55 ENSG00000251876
 .
 56402
 0.16
chr16_67441027_67441178 0.49 ZDHHC1
 zinc finger, DHHC-type containing 1
 6208
 0.11
chr2_38099360_38099826 0.46 RMDN2
 regulator of microtubule dynamics 2
 50737
 0.16
chr13_107025163_107025401 0.34 EFNB2
 ephrin-B2
 162180
 0.04
chr2_129063259_129063630 0.34 HS6ST1
 heparan sulfate 6-O-sulfotransferase 1
 12707
 0.24
chr1_157972060_157972325 0.34 KIRREL
 kin of IRRE like (Drosophila)
 8757
 0.22
chr5_38463728_38464142 0.34 CTD-2263F21.1
4474
 0.2
chr3_197193587_197193738 0.34 BDH1
 3-hydroxybutyrate dehydrogenase, type 1
 47604
 0.16
chr1_68036465_68036756 0.33 ENSG00000207504
 .
 29800
 0.2
chr3_125230252_125231290 0.32 ENSG00000201800
 .
 5052
 0.18
chr1_17559878_17560367 0.32 PADI1
 peptidyl arginine deiminase, type I
 272
 0.9
chr3_111581987_111582138 0.32 PHLDB2
 pleckstrin homology-like domain, family B, member 2
 3419
 0.33
chr8_23780024_23780175 0.31 STC1
 stanniocalcin 1
 67779
 0.11
chr22_18452853_18453098 0.31 ENSG00000207780
 .
 10752
 0.16
chr16_15135229_15135584 0.31 NTAN1
 N-terminal asparagine amidase
 14490
 0.12
chr13_34931777_34932168 0.31 ENSG00000199196
 .
 256997
 0.02
chr5_88082371_88082821 0.31 MEF2C
 myocyte enhancer factor 2C
 37009
 0.19
chrX_13395676_13395827 0.30 ATXN3L
 ataxin 3-like
 57233
 0.14
chr6_150589389_150589540 0.30 ENSG00000201628
 .
 58435
 0.12
chr6_3472796_3472947 0.30 SLC22A23
 solute carrier family 22, member 23
 15615
 0.27
chr7_134483017_134483168 0.30 CALD1
 caldesmon 1
 18663
 0.27
chr9_97567295_97567893 0.29 ENSG00000252153
 .
 4650
 0.2
chr8_38899691_38899968 0.29 ENSG00000207199
 .
 23627
 0.15
chr7_102515337_102515656 0.29 ENSG00000238324
 .
 17599
 0.16
chr1_212844814_212845399 0.29 ENSG00000207491
 .
 20500
 0.14
chr19_11379736_11379971 0.29 DOCK6
 dedicator of cytokinesis 6
 6725
 0.11
chr18_43381728_43382214 0.29 SIGLEC15
 sialic acid binding Ig-like lectin 15
 23506
 0.18
chr1_11219081_11219232 0.29 ENSG00000253086
 .
 6749
 0.12
chr11_10401385_10401536 0.29 ENSG00000221574
 .
 19404
 0.18
chr9_96902563_96902834 0.29 ENSG00000199165
 .
 35536
 0.13
chr1_27626340_27626505 0.29 TMEM222
 transmembrane protein 222
 22229
 0.11
chr1_235133357_235133864 0.29 ENSG00000239690
 .
 93677
 0.08
chr15_34531267_34531418 0.28 EMC4
 ER membrane protein complex subunit 4
 11446
 0.14
chr4_8279768_8280067 0.28 HTRA3
 HtrA serine peptidase 3
 8413
 0.23
chr6_34579346_34579497 0.28 SPDEF
 SAM pointed domain containing ETS transcription factor
 55311
 0.09
chr9_738796_739027 0.28 KANK1
 KN motif and ankyrin repeat domains 1
 6295
 0.26
chr5_16889984_16890135 0.28 MYO10
 myosin X
 26577
 0.18
chr2_163100407_163100558 0.28 FAP
 fibroblast activation protein, alpha
 437
 0.87
chr9_111240432_111240727 0.28 ENSG00000222512
 .
 119370
 0.06
chr12_125140025_125140381 0.27 NCOR2
 nuclear receptor corepressor 2
 88193
 0.09
chr1_234755566_234755985 0.27 IRF2BP2
 interferon regulatory factor 2 binding protein 2
 10504
 0.19
chr6_37423751_37423902 0.27 CMTR1
 cap methyltransferase 1
 19269
 0.19
chr3_45595189_45595741 0.27 ENSG00000251927
 .
 38282
 0.14
chr4_57946942_57947313 0.27 ENSG00000238541
 .
 25384
 0.14
chr8_49341467_49342503 0.27 ENSG00000252710
 .
 121395
 0.06
chr21_27762806_27762957 0.27 AP001596.6
426
 0.86
chr16_73080724_73080969 0.27 ZFHX3
 zinc finger homeobox 3
 1428
 0.47
chr18_67913117_67913400 0.27 RTTN
 rotatin
 40077
 0.17
chr3_27565967_27566162 0.26 ENSG00000201033
 .
 10702
 0.2
chr9_22104325_22104476 0.26 CDKN2B-AS1
 CDKN2B antisense RNA 1
 9277
 0.26
chr4_8192745_8193409 0.26 SH3TC1
 SH3 domain and tetratricopeptide repeats 1
 8014
 0.22
chr15_74723736_74724127 0.26 SEMA7A
 semaphorin 7A, GPI membrane anchor (John Milton Hagen blood group)
 2070
 0.25
chr6_9140445_9140596 0.26 SLC35B3
 solute carrier family 35 (adenosine 3'-phospho 5'-phosphosulfate transporter), member B3
 704726
 0.0
chr10_62190055_62190299 0.26 ANK3
 ankyrin 3, node of Ranvier (ankyrin G)
 40689
 0.22
chr10_101152343_101152513 0.26 GOT1
 glutamic-oxaloacetic transaminase 1, soluble
 37774
 0.17
chr2_74803113_74803707 0.26 LOXL3
 lysyl oxidase-like 3
 20593
 0.09
chr12_89938377_89938528 0.26 RP11-981P6.1
16454
 0.12
chr15_74823309_74823460 0.26 ARID3B
 AT rich interactive domain 3B (BRIGHT-like)
 10134
 0.16
chr1_3456323_3456645 0.25 MEGF6
 multiple EGF-like-domains 6
 8472
 0.18
chr17_61356441_61356592 0.25 RP11-269G24.2
34366
 0.16
chr12_65925506_65925921 0.25 MSRB3
 methionine sulfoxide reductase B3
 205058
 0.02
chr4_15452943_15453218 0.25 CC2D2A
 coiled-coil and C2 domain containing 2A
 18409
 0.16
chr15_99439423_99439701 0.25 RP11-654A16.1
2798
 0.29
chr4_77484588_77484771 0.25 ENSG00000263445
 .
 10042
 0.16
chr3_30537171_30537700 0.25 TGFBR2
 transforming growth factor, beta receptor II (70/80kDa)
 110559
 0.07
chr3_73596607_73596758 0.25 PDZRN3
 PDZ domain containing ring finger 3
 14087
 0.24
chr16_72912139_72912450 0.25 ENSG00000251868
 .
 56403
 0.11
chr8_16570287_16570438 0.25 MSR1
 macrophage scavenger receptor 1
 145491
 0.05
chr22_33141298_33141449 0.25 LL22NC01-116C6.1
37790
 0.18
chr15_99271535_99272053 0.25 IGF1R
 insulin-like growth factor 1 receptor
 20734
 0.22
chr1_59050905_59051237 0.25 TACSTD2
 tumor-associated calcium signal transducer 2
 7905
 0.21
chr19_47234584_47234910 0.25 CTB-174O21.2
2887
 0.12
chr20_60931015_60931270 0.25 RP11-157P1.5
3073
 0.16
chr10_116394275_116394426 0.25 ENSG00000238577
 .
 21919
 0.21
chr16_59732879_59733030 0.25 RP11-105C20.2
 Uncharacterized protein
 55764
 0.17
chr9_121765469_121765620 0.24 BRINP1
 bone morphogenetic protein/retinoic acid inducible neural-specific 1
 366159
 0.01
chr7_127526528_127526679 0.24 SND1
 staphylococcal nuclease and tudor domain containing 1
 1362
 0.57
chr12_52541532_52541683 0.24 ENSG00000265804
 .
 33898
 0.09
chr10_36778471_36778622 0.24 NAMPTL
 nicotinamide phosphoribosyltransferase-like
 33777
 0.21
chr6_140384059_140384419 0.24 ENSG00000252107
 .
 95592
 0.09
chr1_110476345_110476632 0.24 CSF1
 colony stimulating factor 1 (macrophage)
 22880
 0.15
chr5_95592588_95592739 0.24 ENSG00000206997
 .
 46732
 0.18
chr20_43966974_43967184 0.24 SDC4
 syndecan 4
 9985
 0.12
chr14_88937886_88938037 0.24 PTPN21
 protein tyrosine phosphatase, non-receptor type 21
 2001
 0.3
chr21_47480957_47481280 0.24 AP001471.1
36326
 0.12
chr6_53445863_53446014 0.24 GCLC
 glutamate-cysteine ligase, catalytic subunit
 35830
 0.15
chr17_62051771_62052003 0.24 SCN4A
 sodium channel, voltage-gated, type IV, alpha subunit
 1609
 0.28
chr5_71622210_71622361 0.24 PTCD2
 pentatricopeptide repeat domain 2
 6060
 0.19
chr3_43770825_43770976 0.24 ABHD5
 abhydrolase domain containing 5
 17701
 0.24
chr7_129912749_129913103 0.24 CPA2
 carboxypeptidase A2 (pancreatic)
 6259
 0.15
chr10_127836908_127837102 0.24 ENSG00000222740
 .
 2854
 0.38
chr2_36715343_36715494 0.24 CRIM1
 cysteine rich transmembrane BMP regulator 1 (chordin-like)
 25415
 0.18
chr2_43746582_43747032 0.24 THADA
 thyroid adenoma associated
 50847
 0.15
chr2_75730636_75730787 0.24 ENSG00000238410
 .
 14009
 0.14
chr5_156944293_156944560 0.24 ADAM19
 ADAM metallopeptidase domain 19
 14596
 0.16
chr1_197751092_197751472 0.24 DENND1B
 DENN/MADD domain containing 1B
 6519
 0.24
chr3_149096434_149096694 0.24 TM4SF1-AS1
 TM4SF1 antisense RNA 1
 558
 0.59
chr2_112461565_112461786 0.24 ENSG00000266063
 .
 67036
 0.13
chr5_71448848_71449179 0.23 ENSG00000264099
 .
 16281
 0.23
chr15_33149195_33149346 0.23 FMN1
 formin 1
 31185
 0.18
chr4_75072940_75073180 0.23 AC093677.1
 Uncharacterized protein
 48975
 0.12
chr1_2145701_2146237 0.23 AL590822.1
 Uncharacterized protein
 349
 0.81
chr5_121462821_121463158 0.23 ZNF474
 zinc finger protein 474
 2219
 0.3
chr4_77906953_77907316 0.23 SEPT11
 septin 11
 957
 0.65
chr17_56309797_56310163 0.23 LPO
 lactoperoxidase
 5807
 0.14
chrX_39756614_39756930 0.23 ENSG00000263972
 .
 59957
 0.15
chr14_64081611_64082063 0.23 ENSG00000202490
 .
 2924
 0.18
chr8_98000923_98001119 0.23 CPQ
 carboxypeptidase Q
 40676
 0.21
chr1_180268578_180268834 0.23 RP5-1180C10.2
23347
 0.21
chr12_2397196_2397863 0.23 CACNA1C-IT3
 CACNA1C intronic transcript 3 (non-protein coding)
 18587
 0.24
chr4_72117195_72117346 0.23 SLC4A4
 solute carrier family 4 (sodium bicarbonate cotransporter), member 4
 64226
 0.15
chr11_65682626_65682804 0.23 C11orf68
 chromosome 11 open reading frame 68
 3116
 0.11
chr8_103740973_103741124 0.23 ENSG00000266799
 .
 4899
 0.26
chr17_59392029_59392180 0.23 RP11-332H18.3
68042
 0.09
chr7_50602464_50602700 0.23 AC018705.5
3125
 0.27
chr18_55671000_55671151 0.23 ENSG00000265200
 .
 13041
 0.24
chr2_65598363_65598650 0.23 SPRED2
 sprouty-related, EVH1 domain containing 2
 4722
 0.25
chr2_162275033_162275920 0.23 TBR1
 T-box, brain, 1
 1070
 0.48
chr7_75401991_75402142 0.23 CCL26
 chemokine (C-C motif) ligand 26
 491
 0.8
chr5_77793836_77794265 0.23 LHFPL2
 lipoma HMGIC fusion partner-like 2
 50924
 0.17
chr6_125325392_125325543 0.23 RNF217
 ring finger protein 217
 20953
 0.23
chr1_94282304_94282939 0.23 ENSG00000211575
 .
 29767
 0.15
chr6_127786446_127786597 0.23 KIAA0408
 KIAA0408
 5985
 0.27
chr1_230223105_230223256 0.23 GALNT2
 UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 2 (GalNAc-T2)
 20162
 0.23
chr16_54002972_54003123 0.23 RP11-357N13.3
12777
 0.19
chr19_12917574_12918297 0.23 RNASEH2A
 ribonuclease H2, subunit A
 541
 0.5
chr11_122582836_122583051 0.23 ENSG00000239079
 .
 14076
 0.23
chr20_9389776_9389927 0.23 PLCB4
 phospholipase C, beta 4
 101404
 0.07
chr10_62606007_62606158 0.23 CDK1
 cyclin-dependent kinase 1
 66171
 0.12
chr19_13841374_13841557 0.23 CCDC130
 coiled-coil domain containing 130
 1109
 0.39
chr2_47452652_47452803 0.23 CALM2
 calmodulin 2 (phosphorylase kinase, delta)
 48987
 0.13
chr5_39759341_39759548 0.23 DAB2
 Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila)
 297042
 0.01
chr9_124161774_124161925 0.23 RP11-162D16.2
24330
 0.15
chr3_152787726_152787975 0.23 RP11-529G21.2
91714
 0.08
chr1_206686695_206686846 0.23 RASSF5
 Ras association (RalGDS/AF-6) domain family member 5
 5891
 0.16
chr18_55981901_55982052 0.22 NEDD4L
 neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase
 8576
 0.23
chr1_10588124_10588275 0.22 PEX14
 peroxisomal biogenesis factor 14
 53160
 0.09
chr8_74282935_74283532 0.22 RP11-434I12.2
14537
 0.25
chr11_125318368_125318519 0.22 FEZ1
 fasciculation and elongation protein zeta 1 (zygin I)
 33086
 0.15
chr2_218559324_218559720 0.22 DIRC3
 disrupted in renal carcinoma 3
 61756
 0.14
chr1_97603736_97604015 0.22 DPYD-AS1
 DPYD antisense RNA 1
 42396
 0.21
chr20_10905923_10906156 0.22 RP11-103J8.1
23107
 0.27
chr11_33743104_33743255 0.22 CD59
 CD59 molecule, complement regulatory protein
 823
 0.56
chr12_27701944_27702208 0.22 PPFIBP1
 PTPRF interacting protein, binding protein 1 (liprin beta 1)
 11020
 0.23
chr1_162666067_162666218 0.22 DDR2
 discoidin domain receptor tyrosine kinase 2
 63882
 0.1
chr3_106329240_106329391 0.22 ENSG00000200361
 .
 78210
 0.11
chr15_40622287_40622525 0.22 ENSG00000252714
 .
 1443
 0.2
chr2_158695609_158696251 0.22 ACVR1
 activin A receptor, type I
 1091
 0.53
chr7_55260939_55261090 0.22 EGFR-AS1
 EGFR antisense RNA 1
 4387
 0.33
chr3_124904883_124905158 0.22 SLC12A8
 solute carrier family 12, member 8
 4274
 0.25
chr12_76660924_76661075 0.22 ENSG00000223273
 .
 48532
 0.16
chr4_79705695_79705981 0.22 BMP2K
 BMP2 inducible kinase
 8306
 0.19
chr3_134076361_134076562 0.22 AMOTL2
 angiomotin like 2
 14293
 0.22
chr5_131631159_131631712 0.22 P4HA2
 prolyl 4-hydroxylase, alpha polypeptide II
 471
 0.69
chr9_77678975_77679126 0.22 NMRK1
 nicotinamide riboside kinase 1
 24056
 0.14
chr13_76259014_76259165 0.22 LMO7
 LIM domain 7
 48630
 0.13
chr10_21625403_21625600 0.22 ENSG00000207264
 .
 14611
 0.25
chr9_124581839_124582120 0.22 RP11-244O19.1
248
 0.95
chr17_42619678_42619899 0.22 FZD2
 frizzled family receptor 2
 15137
 0.17
chr13_74784840_74784991 0.22 KLF12
 Kruppel-like factor 12
 76521
 0.11
chr19_13147816_13148089 0.22 NFIX
 nuclear factor I/X (CCAAT-binding transcription factor)
 12141
 0.1
chr15_74244046_74244221 0.22 LOXL1-AS1
 LOXL1 antisense RNA 1
 23544
 0.12
chr2_174013244_174013468 0.22 MLTK
 Mitogen-activated protein kinase kinase kinase MLT
 58009
 0.13
chr16_55533264_55533509 0.22 LPCAT2
 lysophosphatidylcholine acyltransferase 2
 9524
 0.21
chr1_185452867_185453160 0.22 ENSG00000252407
 .
 49637
 0.16
chr14_89653293_89653444 0.22 FOXN3
 forkhead box N3
 6280
 0.31
chr5_395973_396219 0.22 AHRR
 aryl-hydrocarbon receptor repressor
 24939
 0.14
chr9_78990381_78990532 0.22 RFK
 riboflavin kinase
 18592
 0.24
chr1_171189915_171190066 0.22 RP1-127D3.4
3433
 0.19
chr16_88340108_88340439 0.21 ZNF469
 zinc finger protein 469
 153606
 0.04
chr3_127469623_127470054 0.21 MGLL
 monoglyceride lipase
 14638
 0.23
chr14_54636067_54636218 0.21 BMP4
 bone morphogenetic protein 4
 210663
 0.02
chr6_43083911_43084141 0.21 PTK7
 protein tyrosine kinase 7
 14303
 0.11
chr17_47694081_47694342 0.21 SPOP
 speckle-type POZ protein
 29773
 0.11
chr1_203539117_203539268 0.21 ATP2B4
 ATPase, Ca++ transporting, plasma membrane 4
 56497
 0.12
chr16_88839995_88840537 0.21 PIEZO1
 piezo-type mechanosensitive ion channel component 1
 11353
 0.09
chr1_186071380_186071531 0.21 HMCN1
 hemicentin 1
 69064
 0.12
chr6_119469482_119469711 0.21 FAM184A
 family with sequence similarity 184, member A
 756
 0.75
chr3_120397975_120398149 0.21 HGD
 homogentisate 1,2-dioxygenase
 2898
 0.32
chr15_43809364_43809657 0.21 MAP1A
 microtubule-associated protein 1A
 296
 0.87
chr7_23387609_23387938 0.21 ENSG00000212264
 .
 48292
 0.12
chr15_22904161_22904312 0.21 CYFIP1
 cytoplasmic FMR1 interacting protein 1
 11520
 0.2
chr5_58376080_58376374 0.21 RP11-266N13.2
40639
 0.18
chr3_45102518_45102669 0.21 ENSG00000252410
 .
 26513
 0.16
chr9_97675641_97675792 0.21 RP11-49O14.2
13005
 0.18
chr5_163631145_163631296 0.21 CTC-340A15.2
92482
 0.1
chr2_110863867_110864081 0.21 MALL
 mal, T-cell differentiation protein-like
 9625
 0.15
chr10_104387858_104388403 0.21 TRIM8
 tripartite motif containing 8
 16123
 0.16
chr11_102706754_102706905 0.21 MMP3
 matrix metallopeptidase 3 (stromelysin 1, progelatinase)
 2612
 0.26
chr5_144740955_144741106 0.21 ENSG00000221467
 .
 163692
 0.04
chr3_185434712_185435102 0.21 C3orf65
 chromosome 3 open reading frame 65
 3827
 0.28
chr2_9375414_9375688 0.21 ASAP2
 ArfGAP with SH3 domain, ankyrin repeat and PH domain 2
 28657
 0.24
chr10_80384244_80384395 0.21 ENSG00000223243
 .
 126040
 0.06
chr6_166778430_166778581 0.21 MPC1
 mitochondrial pyruvate carrier 1
 17981
 0.15
chr21_46829481_46829632 0.21 COL18A1-AS2
 COL18A1 antisense RNA 2
 424
 0.8
chr2_159901322_159901473 0.21 ENSG00000202029
 .
 17743
 0.24
chr4_129149422_129149689 0.21 PGRMC2
 progesterone receptor membrane component 2
 44661
 0.2
chr1_208358171_208358322 0.21 PLXNA2
 plexin A2
 59419
 0.17
chr1_25039474_25039625 0.21 CLIC4
 chloride intracellular channel 4
 32299
 0.15

Histogram of CRE-TSS distances for CREs targeted by :

Histogram of

Rank distribution of CRE target scores:

Histogram of target CRE score.

Distribution of target CREs across different genomic regions:

Weighted Piechart of Weighted Piechart of Weighted Piechart of

Network of associatons between targets according to the STRING database.

First level regulatory network of OLIG2_NEUROD1_ATOH1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:1903053 regulation of extracellular matrix disassembly(GO:0010715) negative regulation of extracellular matrix disassembly(GO:0010716) regulation of extracellular matrix organization(GO:1903053) negative regulation of extracellular matrix organization(GO:1903054)
0.1 0.4 GO:0018101 protein citrullination(GO:0018101)
0.1 0.3 GO:0071318 cellular response to ATP(GO:0071318)
0.1 0.2 GO:0060831 smoothened signaling pathway involved in dorsal/ventral neural tube patterning(GO:0060831)
0.1 0.2 GO:0060083 smooth muscle contraction involved in micturition(GO:0060083)
0.1 0.2 GO:0006003 fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.1 0.1 GO:0007221 positive regulation of transcription of Notch receptor target(GO:0007221)
0.1 0.2 GO:0035583 sequestering of extracellular ligand from receptor(GO:0035581) sequestering of TGFbeta in extracellular matrix(GO:0035583) protein localization to extracellular region(GO:0071692) maintenance of protein location in extracellular region(GO:0071694) extracellular regulation of signal transduction(GO:1900115) extracellular negative regulation of signal transduction(GO:1900116)
0.1 0.2 GO:0018401 peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401) 4-hydroxyproline metabolic process(GO:0019471) peptidyl-proline hydroxylation(GO:0019511)
0.1 0.2 GO:0010766 negative regulation of sodium ion transport(GO:0010766)
0.1 0.1 GO:0060028 convergent extension involved in axis elongation(GO:0060028)
0.0 0.1 GO:0030011 maintenance of cell polarity(GO:0030011)
0.0 0.2 GO:0007028 cytoplasm organization(GO:0007028)
0.0 0.2 GO:0048096 chromatin-mediated maintenance of transcription(GO:0048096)
0.0 0.3 GO:0032909 transforming growth factor beta2 production(GO:0032906) regulation of transforming growth factor beta2 production(GO:0032909)
0.0 0.1 GO:0002072 optic cup morphogenesis involved in camera-type eye development(GO:0002072)
0.0 0.2 GO:0060539 diaphragm development(GO:0060539)
0.0 0.2 GO:0021535 cell migration in hindbrain(GO:0021535)
0.0 0.2 GO:0045618 positive regulation of keratinocyte differentiation(GO:0045618)
0.0 0.1 GO:0060394 negative regulation of pathway-restricted SMAD protein phosphorylation(GO:0060394)
0.0 0.1 GO:0018243 protein O-linked glycosylation via serine(GO:0018242) protein O-linked glycosylation via threonine(GO:0018243)
0.0 0.1 GO:0032467 positive regulation of cytokinesis(GO:0032467)
0.0 0.1 GO:0045198 establishment of epithelial cell apical/basal polarity(GO:0045198)
0.0 0.1 GO:0033173 calcineurin-NFAT signaling cascade(GO:0033173)
0.0 0.2 GO:0060666 dichotomous subdivision of terminal units involved in salivary gland branching(GO:0060666)
0.0 0.2 GO:0045662 negative regulation of myoblast differentiation(GO:0045662)
0.0 0.2 GO:0006307 DNA dealkylation involved in DNA repair(GO:0006307)
0.0 0.1 GO:0031946 regulation of glucocorticoid biosynthetic process(GO:0031946)
0.0 0.1 GO:0002085 inhibition of neuroepithelial cell differentiation(GO:0002085)
0.0 0.1 GO:0009169 purine nucleoside monophosphate catabolic process(GO:0009128) ribonucleoside monophosphate catabolic process(GO:0009158) purine ribonucleoside monophosphate catabolic process(GO:0009169)
0.0 0.1 GO:0034201 response to oleic acid(GO:0034201)
0.0 0.1 GO:0002043 blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:0002043)
0.0 0.1 GO:0022617 extracellular matrix disassembly(GO:0022617)
0.0 0.1 GO:0019852 L-ascorbic acid metabolic process(GO:0019852)
0.0 0.1 GO:0008218 bioluminescence(GO:0008218)
0.0 0.1 GO:0014819 regulation of skeletal muscle contraction(GO:0014819)
0.0 0.1 GO:0070427 nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070427)
0.0 0.1 GO:0032497 detection of lipopolysaccharide(GO:0032497)
0.0 0.1 GO:0031340 positive regulation of vesicle fusion(GO:0031340)
0.0 0.1 GO:0014012 peripheral nervous system axon regeneration(GO:0014012)
0.0 0.2 GO:0090136 epithelial cell-cell adhesion(GO:0090136)
0.0 0.1 GO:0032277 negative regulation of gonadotropin secretion(GO:0032277)
0.0 0.1 GO:0010662 striated muscle cell apoptotic process(GO:0010658) cardiac muscle cell apoptotic process(GO:0010659) regulation of striated muscle cell apoptotic process(GO:0010662) negative regulation of striated muscle cell apoptotic process(GO:0010664) regulation of cardiac muscle cell apoptotic process(GO:0010665) negative regulation of cardiac muscle cell apoptotic process(GO:0010667)
0.0 0.1 GO:0007132 meiotic metaphase I(GO:0007132)
0.0 0.1 GO:0032926 negative regulation of activin receptor signaling pathway(GO:0032926)
0.0 0.3 GO:0019369 arachidonic acid metabolic process(GO:0019369)
0.0 0.1 GO:0072311 renal filtration cell differentiation(GO:0061318) glomerular epithelium development(GO:0072010) glomerular visceral epithelial cell differentiation(GO:0072112) glomerular epithelial cell differentiation(GO:0072311)
0.0 0.1 GO:0090049 regulation of cell migration involved in sprouting angiogenesis(GO:0090049) regulation of sprouting angiogenesis(GO:1903670)
0.0 0.1 GO:0043589 skin morphogenesis(GO:0043589)
0.0 0.1 GO:0051045 negative regulation of membrane protein ectodomain proteolysis(GO:0051045)
0.0 0.2 GO:0015840 urea transport(GO:0015840)
0.0 0.1 GO:0001996 positive regulation of heart rate by epinephrine-norepinephrine(GO:0001996)
0.0 0.1 GO:0060159 regulation of dopamine receptor signaling pathway(GO:0060159)
0.0 0.1 GO:0014848 urinary tract smooth muscle contraction(GO:0014848)
0.0 0.1 GO:2000050 regulation of non-canonical Wnt signaling pathway(GO:2000050)
0.0 0.1 GO:0030490 maturation of SSU-rRNA(GO:0030490)
0.0 0.1 GO:0045077 negative regulation of interferon-gamma biosynthetic process(GO:0045077)
0.0 0.1 GO:0060014 granulosa cell differentiation(GO:0060014)
0.0 0.1 GO:0060907 positive regulation of macrophage cytokine production(GO:0060907)
0.0 0.1 GO:0060528 secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development(GO:0060528)
0.0 0.0 GO:0061081 positive regulation of myeloid leukocyte cytokine production involved in immune response(GO:0061081)
0.0 0.0 GO:0045112 integrin biosynthetic process(GO:0045112)
0.0 0.0 GO:0001778 plasma membrane repair(GO:0001778)
0.0 0.2 GO:0090399 replicative senescence(GO:0090399)
0.0 0.0 GO:0055089 fatty acid homeostasis(GO:0055089)
0.0 0.1 GO:0032455 nerve growth factor processing(GO:0032455)
0.0 0.1 GO:1900078 positive regulation of insulin receptor signaling pathway(GO:0046628) positive regulation of cellular response to insulin stimulus(GO:1900078)
0.0 0.1 GO:0048170 positive regulation of long-term neuronal synaptic plasticity(GO:0048170)
0.0 0.1 GO:0048149 behavioral response to ethanol(GO:0048149)
0.0 0.1 GO:0007619 courtship behavior(GO:0007619)
0.0 0.1 GO:0009756 carbohydrate mediated signaling(GO:0009756)
0.0 0.1 GO:0070092 regulation of glucagon secretion(GO:0070092)
0.0 0.0 GO:0019934 cGMP-mediated signaling(GO:0019934)
0.0 0.1 GO:0021670 lateral ventricle development(GO:0021670)
0.0 0.1 GO:0032331 negative regulation of chondrocyte differentiation(GO:0032331)
0.0 0.1 GO:0071277 cellular response to calcium ion(GO:0071277)
0.0 0.1 GO:0051124 synaptic growth at neuromuscular junction(GO:0051124)
0.0 0.1 GO:0022605 oogenesis stage(GO:0022605)
0.0 0.2 GO:0014821 phasic smooth muscle contraction(GO:0014821)
0.0 0.1 GO:0048755 branching morphogenesis of a nerve(GO:0048755)
0.0 0.0 GO:0060596 mammary placode formation(GO:0060596)
0.0 0.1 GO:0072383 plus-end-directed vesicle transport along microtubule(GO:0072383) plus-end-directed organelle transport along microtubule(GO:0072386)
0.0 0.1 GO:0061302 smooth muscle cell-matrix adhesion(GO:0061302)
0.0 0.1 GO:0061072 iris morphogenesis(GO:0061072)
0.0 0.2 GO:0007185 transmembrane receptor protein tyrosine phosphatase signaling pathway(GO:0007185)
0.0 0.1 GO:0006337 nucleosome disassembly(GO:0006337) chromatin disassembly(GO:0031498) protein-DNA complex disassembly(GO:0032986)
0.0 0.1 GO:0030321 transepithelial chloride transport(GO:0030321)
0.0 0.0 GO:0002025 vasodilation by norepinephrine-epinephrine involved in regulation of systemic arterial blood pressure(GO:0002025)
0.0 0.1 GO:0070254 mucus secretion(GO:0070254)
0.0 0.1 GO:0006646 phosphatidylethanolamine biosynthetic process(GO:0006646) phosphatidylethanolamine metabolic process(GO:0046337)
0.0 0.1 GO:0006654 phosphatidic acid biosynthetic process(GO:0006654)
0.0 0.1 GO:0048016 inositol phosphate-mediated signaling(GO:0048016)
0.0 0.0 GO:0090162 establishment of epithelial cell polarity(GO:0090162)
0.0 0.1 GO:0051176 positive regulation of sulfur metabolic process(GO:0051176)
0.0 0.1 GO:0090073 positive regulation of protein homodimerization activity(GO:0090073)
0.0 0.0 GO:0006166 purine ribonucleoside salvage(GO:0006166)
0.0 0.1 GO:0018345 protein palmitoylation(GO:0018345)
0.0 0.0 GO:0033630 positive regulation of cell adhesion mediated by integrin(GO:0033630)
0.0 0.0 GO:0060433 bronchus development(GO:0060433)
0.0 0.0 GO:0042726 flavin-containing compound metabolic process(GO:0042726)
0.0 0.3 GO:0048286 lung alveolus development(GO:0048286)
0.0 0.1 GO:0070189 kynurenine metabolic process(GO:0070189)
0.0 0.1 GO:0051497 negative regulation of stress fiber assembly(GO:0051497)
0.0 0.0 GO:0002238 response to molecule of fungal origin(GO:0002238)
0.0 0.1 GO:0006572 tyrosine catabolic process(GO:0006572)
0.0 0.1 GO:0045079 negative regulation of chemokine biosynthetic process(GO:0045079)
0.0 0.0 GO:0045617 negative regulation of keratinocyte differentiation(GO:0045617)
0.0 0.1 GO:0000103 sulfate assimilation(GO:0000103)
0.0 0.0 GO:0007598 blood coagulation, extrinsic pathway(GO:0007598)
0.0 0.0 GO:0060449 bud elongation involved in lung branching(GO:0060449)
0.0 0.1 GO:0009296 obsolete flagellum assembly(GO:0009296)
0.0 0.0 GO:0003308 negative regulation of Wnt signaling pathway involved in heart development(GO:0003308)
0.0 0.1 GO:0006663 platelet activating factor biosynthetic process(GO:0006663)
0.0 0.1 GO:0033137 negative regulation of peptidyl-serine phosphorylation(GO:0033137)
0.0 0.1 GO:0008215 spermine metabolic process(GO:0008215)
0.0 0.1 GO:0032836 glomerular basement membrane development(GO:0032836)
0.0 0.2 GO:0035329 hippo signaling(GO:0035329)
0.0 0.1 GO:0090084 negative regulation of inclusion body assembly(GO:0090084)
0.0 0.1 GO:0010701 positive regulation of norepinephrine secretion(GO:0010701)
0.0 0.1 GO:0006975 DNA damage induced protein phosphorylation(GO:0006975)
0.0 0.1 GO:0002689 negative regulation of leukocyte chemotaxis(GO:0002689)
0.0 0.1 GO:0030091 protein repair(GO:0030091)
0.0 0.1 GO:0006562 proline catabolic process(GO:0006562)
0.0 0.1 GO:0072367 regulation of lipid transport by regulation of transcription from RNA polymerase II promoter(GO:0072367)
0.0 0.1 GO:0046951 ketone body biosynthetic process(GO:0046951)
0.0 0.1 GO:0009249 protein lipoylation(GO:0009249)
0.0 0.0 GO:0051005 negative regulation of lipoprotein lipase activity(GO:0051005)
0.0 0.1 GO:0048261 negative regulation of receptor-mediated endocytosis(GO:0048261)
0.0 0.1 GO:0060039 pericardium development(GO:0060039)
0.0 0.0 GO:0030812 negative regulation of nucleotide catabolic process(GO:0030812)
0.0 0.0 GO:0048312 intracellular distribution of mitochondria(GO:0048312)
0.0 0.1 GO:0009629 response to gravity(GO:0009629)
0.0 0.1 GO:0071320 cellular response to cAMP(GO:0071320)
0.0 0.1 GO:0048172 regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.0 0.0 GO:0090009 primitive streak formation(GO:0090009)
0.0 0.0 GO:0045683 negative regulation of epidermis development(GO:0045683)
0.0 0.1 GO:0090231 regulation of spindle checkpoint(GO:0090231)
0.0 0.2 GO:0015701 bicarbonate transport(GO:0015701)
0.0 0.0 GO:0046475 glycerophospholipid catabolic process(GO:0046475)
0.0 0.1 GO:0040015 negative regulation of multicellular organism growth(GO:0040015)
0.0 0.0 GO:0035414 negative regulation of catenin import into nucleus(GO:0035414)
0.0 0.0 GO:0045906 negative regulation of vasoconstriction(GO:0045906)
0.0 0.0 GO:0072677 eosinophil chemotaxis(GO:0048245) eosinophil migration(GO:0072677)
0.0 0.1 GO:0007020 microtubule nucleation(GO:0007020)
0.0 0.1 GO:0008228 opsonization(GO:0008228)
0.0 0.1 GO:0035413 positive regulation of catenin import into nucleus(GO:0035413)
0.0 0.0 GO:0070050 neuron cellular homeostasis(GO:0070050)
0.0 0.0 GO:0003148 outflow tract septum morphogenesis(GO:0003148)
0.0 0.0 GO:0043931 ossification involved in bone maturation(GO:0043931)
0.0 0.0 GO:0003321 positive regulation of blood pressure by epinephrine-norepinephrine(GO:0003321)
0.0 0.1 GO:0002634 regulation of germinal center formation(GO:0002634)
0.0 0.1 GO:0043569 negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569)
0.0 0.3 GO:0030574 collagen catabolic process(GO:0030574)
0.0 0.0 GO:0002686 negative regulation of leukocyte migration(GO:0002686)
0.0 0.1 GO:0006072 glycerol-3-phosphate metabolic process(GO:0006072)
0.0 0.1 GO:0007016 cytoskeletal anchoring at plasma membrane(GO:0007016)
0.0 0.0 GO:0002679 respiratory burst involved in defense response(GO:0002679)
0.0 0.1 GO:0032055 negative regulation of translation in response to stress(GO:0032055)
0.0 0.0 GO:0016576 histone dephosphorylation(GO:0016576)
0.0 0.0 GO:0006552 leucine catabolic process(GO:0006552)
0.0 0.0 GO:0072048 pattern specification involved in kidney development(GO:0061004) renal system pattern specification(GO:0072048) pattern specification involved in metanephros development(GO:0072268)
0.0 0.0 GO:0070100 Roundabout signaling pathway(GO:0035385) regulation of chemokine-mediated signaling pathway(GO:0070099) negative regulation of chemokine-mediated signaling pathway(GO:0070100)
0.0 0.1 GO:0002040 sprouting angiogenesis(GO:0002040)
0.0 0.0 GO:0070933 histone H3 deacetylation(GO:0070932) histone H4 deacetylation(GO:0070933)
0.0 0.0 GO:0032506 cytokinetic process(GO:0032506)
0.0 0.1 GO:0051319 mitotic G2 phase(GO:0000085) G2 phase(GO:0051319)
0.0 0.0 GO:0036072 intramembranous ossification(GO:0001957) direct ossification(GO:0036072)
0.0 0.0 GO:0071731 response to nitric oxide(GO:0071731)
0.0 0.1 GO:0097061 dendritic spine morphogenesis(GO:0060997) regulation of dendritic spine morphogenesis(GO:0061001) dendritic spine organization(GO:0097061)
0.0 0.0 GO:0006452 translational frameshifting(GO:0006452) positive regulation of translational elongation(GO:0045901) positive regulation of translational termination(GO:0045905)
0.0 0.0 GO:0035461 vitamin transmembrane transport(GO:0035461)
0.0 0.0 GO:0045657 positive regulation of monocyte differentiation(GO:0045657)
0.0 0.0 GO:0032020 ISG15-protein conjugation(GO:0032020)
0.0 0.0 GO:0015793 glycerol transport(GO:0015793)
0.0 0.0 GO:0001955 blood vessel maturation(GO:0001955)
0.0 0.0 GO:2000300 regulation of synaptic vesicle transport(GO:1902803) regulation of synaptic vesicle exocytosis(GO:2000300)
0.0 0.1 GO:0007528 neuromuscular junction development(GO:0007528)
0.0 0.1 GO:0017187 peptidyl-glutamic acid carboxylation(GO:0017187) protein carboxylation(GO:0018214)
0.0 0.0 GO:0000470 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000463) maturation of LSU-rRNA(GO:0000470)
0.0 0.0 GO:0051790 short-chain fatty acid biosynthetic process(GO:0051790)
0.0 0.1 GO:0009650 UV protection(GO:0009650)
0.0 0.0 GO:1903301 regulation of glucokinase activity(GO:0033131) positive regulation of glucokinase activity(GO:0033133) regulation of hexokinase activity(GO:1903299) positive regulation of hexokinase activity(GO:1903301)
0.0 0.0 GO:0006551 leucine metabolic process(GO:0006551)
0.0 0.0 GO:0046607 positive regulation of centrosome cycle(GO:0046607)
0.0 0.1 GO:0031268 pseudopodium organization(GO:0031268)
0.0 0.0 GO:0043268 positive regulation of potassium ion transport(GO:0043268)
0.0 0.0 GO:0060236 regulation of mitotic spindle organization(GO:0060236)
0.0 0.2 GO:0045104 intermediate filament cytoskeleton organization(GO:0045104)
0.0 0.0 GO:0019614 phenol-containing compound catabolic process(GO:0019336) catechol-containing compound catabolic process(GO:0019614) catecholamine catabolic process(GO:0042424)
0.0 0.0 GO:0051451 myoblast migration(GO:0051451)
0.0 0.0 GO:0090195 chemokine secretion(GO:0090195) regulation of chemokine secretion(GO:0090196) positive regulation of chemokine secretion(GO:0090197)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0071438 invadopodium membrane(GO:0071438)
0.0 0.1 GO:0043260 laminin-11 complex(GO:0043260)
0.0 0.0 GO:0071664 catenin-TCF7L2 complex(GO:0071664)
0.0 0.2 GO:0031362 anchored component of external side of plasma membrane(GO:0031362)
0.0 0.1 GO:0070852 cell body fiber(GO:0070852)
0.0 0.1 GO:0032299 ribonuclease H2 complex(GO:0032299)
0.0 0.2 GO:0030056 hemidesmosome(GO:0030056)
0.0 0.2 GO:0031512 motile primary cilium(GO:0031512)
0.0 0.1 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.0 0.2 GO:0005915 zonula adherens(GO:0005915)
0.0 0.1 GO:0009331 glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.0 0.2 GO:0031332 RISC complex(GO:0016442) RNAi effector complex(GO:0031332)
0.0 0.2 GO:0001527 microfibril(GO:0001527)
0.0 0.2 GO:0098645 network-forming collagen trimer(GO:0098642) collagen network(GO:0098645)
0.0 0.1 GO:0048179 activin receptor complex(GO:0048179)
0.0 0.1 GO:0005588 collagen type V trimer(GO:0005588)
0.0 0.1 GO:0031312 extrinsic component of organelle membrane(GO:0031312)
0.0 0.1 GO:0030934 anchoring collagen complex(GO:0030934)
0.0 0.1 GO:0005863 striated muscle myosin thick filament(GO:0005863)
0.0 0.0 GO:0043083 synaptic cleft(GO:0043083)
0.0 0.2 GO:0002102 podosome(GO:0002102)
0.0 0.1 GO:0070044 synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044)
0.0 0.0 GO:0098651 basement membrane collagen trimer(GO:0098651)
0.0 0.1 GO:0005614 interstitial matrix(GO:0005614)
0.0 0.1 GO:0031430 M band(GO:0031430)
0.0 0.1 GO:0030122 AP-2 adaptor complex(GO:0030122) clathrin coat of endocytic vesicle(GO:0030128)
0.0 0.1 GO:0030061 mitochondrial crista(GO:0030061)
0.0 0.0 GO:0005589 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.0 0.1 GO:0005828 kinetochore microtubule(GO:0005828)
0.0 0.0 GO:0032809 neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.0 0.0 GO:0031904 endosome lumen(GO:0031904)
0.0 0.0 GO:0032591 dendritic spine membrane(GO:0032591)
0.0 0.1 GO:0016585 obsolete chromatin remodeling complex(GO:0016585)
0.0 0.1 GO:0035253 ciliary rootlet(GO:0035253)
0.0 0.0 GO:0042272 nuclear RNA export factor complex(GO:0042272)
0.0 0.1 GO:0008328 ionotropic glutamate receptor complex(GO:0008328) neurotransmitter receptor complex(GO:0098878)
0.0 0.1 GO:0043034 costamere(GO:0043034)
0.0 0.1 GO:0005862 muscle thin filament tropomyosin(GO:0005862)
0.0 0.1 GO:0031233 intrinsic component of external side of plasma membrane(GO:0031233)
0.0 0.2 GO:0030057 desmosome(GO:0030057)
0.0 0.0 GO:0014701 junctional sarcoplasmic reticulum membrane(GO:0014701)
0.0 0.0 GO:0045298 tubulin complex(GO:0045298)
0.0 0.1 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
0.0 0.1 GO:0005861 troponin complex(GO:0005861)
0.0 0.0 GO:0000176 nuclear exosome (RNase complex)(GO:0000176)
0.0 0.1 GO:0005697 telomerase holoenzyme complex(GO:0005697)
0.0 0.1 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.0 0.9 GO:0030016 myofibril(GO:0030016)
0.0 0.0 GO:0070545 PeBoW complex(GO:0070545)
0.0 0.2 GO:0005811 lipid particle(GO:0005811)
0.0 0.1 GO:0005663 DNA replication factor C complex(GO:0005663)
0.0 0.0 GO:0016942 insulin-like growth factor binding protein complex(GO:0016942) growth factor complex(GO:0036454)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0004668 protein-arginine deiminase activity(GO:0004668)
0.1 0.2 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.1 0.2 GO:0004117 calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117)
0.1 0.2 GO:0005010 insulin-like growth factor-activated receptor activity(GO:0005010)
0.1 0.2 GO:0003873 6-phosphofructo-2-kinase activity(GO:0003873)
0.0 0.1 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 0.1 GO:0004995 tachykinin receptor activity(GO:0004995)
0.0 0.2 GO:0031545 procollagen-proline 4-dioxygenase activity(GO:0004656) peptidyl-proline 4-dioxygenase activity(GO:0031545)
0.0 0.2 GO:0030618 transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity(GO:0030618)
0.0 0.1 GO:0005229 intracellular calcium activated chloride channel activity(GO:0005229)
0.0 0.3 GO:0017154 semaphorin receptor activity(GO:0017154)
0.0 0.2 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.0 0.1 GO:0003680 AT DNA binding(GO:0003680)
0.0 0.2 GO:0048027 mRNA 5'-UTR binding(GO:0048027)
0.0 0.1 GO:0016901 oxidoreductase activity, acting on the CH-OH group of donors, quinone or similar compound as acceptor(GO:0016901)
0.0 0.1 GO:0070052 collagen V binding(GO:0070052)
0.0 0.2 GO:0005007 fibroblast growth factor-activated receptor activity(GO:0005007)
0.0 0.1 GO:0005006 epidermal growth factor-activated receptor activity(GO:0005006)
0.0 0.1 GO:0004157 dihydropyrimidinase activity(GO:0004157)
0.0 0.1 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.0 0.1 GO:0004720 protein-lysine 6-oxidase activity(GO:0004720)
0.0 0.0 GO:0008109 N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109)
0.0 0.3 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.0 0.1 GO:0033743 peptide-methionine (R)-S-oxide reductase activity(GO:0033743)
0.0 0.1 GO:0042808 obsolete neuronal Cdc2-like kinase binding(GO:0042808)
0.0 0.1 GO:0035514 DNA demethylase activity(GO:0035514) DNA-N1-methyladenine dioxygenase activity(GO:0043734)
0.0 0.1 GO:0015254 glycerol channel activity(GO:0015254)
0.0 0.1 GO:0015204 urea transmembrane transporter activity(GO:0015204)
0.0 0.1 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.0 0.1 GO:0004103 choline kinase activity(GO:0004103)
0.0 0.1 GO:0036137 kynurenine-oxoglutarate transaminase activity(GO:0016212) kynurenine aminotransferase activity(GO:0036137)
0.0 0.1 GO:0005072 transforming growth factor beta receptor, cytoplasmic mediator activity(GO:0005072)
0.0 0.1 GO:0030297 transmembrane receptor protein tyrosine kinase activator activity(GO:0030297)
0.0 0.1 GO:0031957 very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.0 0.1 GO:0002162 dystroglycan binding(GO:0002162)
0.0 0.1 GO:0070324 thyroid hormone binding(GO:0070324)
0.0 0.2 GO:0017166 vinculin binding(GO:0017166)
0.0 0.1 GO:0004791 thioredoxin-disulfide reductase activity(GO:0004791)
0.0 0.1 GO:0008475 procollagen-lysine 5-dioxygenase activity(GO:0008475)
0.0 0.1 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.0 0.2 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.0 0.2 GO:0051378 serotonin binding(GO:0051378)
0.0 0.1 GO:0004523 RNA-DNA hybrid ribonuclease activity(GO:0004523)
0.0 0.1 GO:0090482 vitamin transmembrane transporter activity(GO:0090482)
0.0 0.1 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.0 0.1 GO:0001849 complement component C1q binding(GO:0001849)
0.0 0.1 GO:0005110 frizzled-2 binding(GO:0005110)
0.0 0.1 GO:0005432 calcium:sodium antiporter activity(GO:0005432)
0.0 0.1 GO:0017080 sodium channel regulator activity(GO:0017080)
0.0 0.1 GO:0008107 galactoside 2-alpha-L-fucosyltransferase activity(GO:0008107) alpha-(1,2)-fucosyltransferase activity(GO:0031127)
0.0 0.1 GO:0016215 stearoyl-CoA 9-desaturase activity(GO:0004768) acyl-CoA desaturase activity(GO:0016215)
0.0 0.1 GO:0015277 kainate selective glutamate receptor activity(GO:0015277)
0.0 0.1 GO:0016361 activin receptor activity, type I(GO:0016361)
0.0 0.1 GO:0070644 vitamin D response element binding(GO:0070644)
0.0 0.1 GO:0008294 calcium- and calmodulin-responsive adenylate cyclase activity(GO:0008294)
0.0 0.1 GO:0001159 RNA polymerase II core promoter proximal region sequence-specific DNA binding(GO:0000978) core promoter proximal region sequence-specific DNA binding(GO:0000987) core promoter proximal region DNA binding(GO:0001159)
0.0 0.1 GO:0048406 nerve growth factor binding(GO:0048406)
0.0 0.1 GO:0050501 hyaluronan synthase activity(GO:0050501)
0.0 0.1 GO:0004470 malic enzyme activity(GO:0004470)
0.0 0.1 GO:0097493 extracellular matrix constituent conferring elasticity(GO:0030023) structural molecule activity conferring elasticity(GO:0097493)
0.0 0.1 GO:0048018 receptor agonist activity(GO:0048018)
0.0 0.1 GO:0005332 gamma-aminobutyric acid:sodium symporter activity(GO:0005332)
0.0 0.1 GO:0015016 [heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
0.0 0.1 GO:0047760 butyrate-CoA ligase activity(GO:0047760)
0.0 0.1 GO:0004321 fatty-acyl-CoA synthase activity(GO:0004321)
0.0 0.1 GO:0042978 ornithine decarboxylase activator activity(GO:0042978)
0.0 0.2 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.0 0.1 GO:0005148 prolactin receptor binding(GO:0005148)
0.0 0.0 GO:0019215 intermediate filament binding(GO:0019215)
0.0 0.1 GO:0019211 phosphatase activator activity(GO:0019211)
0.0 0.0 GO:0004937 alpha1-adrenergic receptor activity(GO:0004937)
0.0 0.2 GO:0005523 tropomyosin binding(GO:0005523)
0.0 0.1 GO:0000832 inositol hexakisphosphate kinase activity(GO:0000828) inositol hexakisphosphate 5-kinase activity(GO:0000832)
0.0 0.2 GO:0005355 glucose transmembrane transporter activity(GO:0005355)
0.0 0.1 GO:0050998 nitric-oxide synthase binding(GO:0050998)
0.0 0.0 GO:0043398 HLH domain binding(GO:0043398)
0.0 0.4 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.0 0.0 GO:0034186 apolipoprotein A-I binding(GO:0034186)
0.0 0.0 GO:0050508 glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0050508)
0.0 0.1 GO:0009374 biotin binding(GO:0009374)
0.0 0.1 GO:0004597 peptide-aspartate beta-dioxygenase activity(GO:0004597)
0.0 0.1 GO:0019966 interleukin-1 binding(GO:0019966)
0.0 0.1 GO:0004128 cytochrome-b5 reductase activity, acting on NAD(P)H(GO:0004128)
0.0 0.1 GO:0051380 norepinephrine binding(GO:0051380)
0.0 0.1 GO:0008503 benzodiazepine receptor activity(GO:0008503)
0.0 0.1 GO:0016724 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.0 0.0 GO:0004477 methenyltetrahydrofolate cyclohydrolase activity(GO:0004477)
0.0 0.1 GO:0070290 N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.0 0.2 GO:0019894 kinesin binding(GO:0019894)
0.0 0.0 GO:0043008 ATP-dependent protein binding(GO:0043008)
0.0 0.1 GO:0046970 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041) histone deacetylase activity (H4-K16 specific)(GO:0034739) NAD-dependent histone deacetylase activity (H4-K16 specific)(GO:0046970)
0.0 0.3 GO:0005520 insulin-like growth factor binding(GO:0005520)
0.0 0.6 GO:0008009 chemokine activity(GO:0008009)
0.0 0.1 GO:0003689 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.0 0.3 GO:0050840 extracellular matrix binding(GO:0050840)
0.0 0.1 GO:0016018 cyclosporin A binding(GO:0016018)
0.0 0.0 GO:0070815 peptidyl-lysine 5-dioxygenase activity(GO:0070815)
0.0 0.0 GO:0008898 S-adenosylmethionine-homocysteine S-methyltransferase activity(GO:0008898)
0.0 0.1 GO:0016641 oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor(GO:0016641)
0.0 0.1 GO:0015280 ligand-gated sodium channel activity(GO:0015280)
0.0 0.1 GO:0070717 poly-purine tract binding(GO:0070717)
0.0 0.0 GO:0047623 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.0 0.0 GO:0004630 phospholipase D activity(GO:0004630)
0.0 0.1 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.0 0.0 GO:0033130 acetylcholine receptor binding(GO:0033130)
0.0 0.0 GO:0016647 oxidoreductase activity, acting on the CH-NH group of donors, oxygen as acceptor(GO:0016647)
0.0 0.2 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.0 0.0 GO:0000309 nicotinamide-nucleotide adenylyltransferase activity(GO:0000309) nicotinate-nucleotide adenylyltransferase activity(GO:0004515)
0.0 0.0 GO:0070700 transmembrane receptor protein serine/threonine kinase binding(GO:0070696) BMP receptor binding(GO:0070700)
0.0 0.1 GO:0043522 leucine zipper domain binding(GO:0043522)
0.0 0.1 GO:0070628 proteasome binding(GO:0070628)
0.0 0.0 GO:0050682 AF-2 domain binding(GO:0050682)
0.0 0.0 GO:0003829 beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity(GO:0003829)
0.0 0.0 GO:0001098 basal transcription machinery binding(GO:0001098) basal RNA polymerase II transcription machinery binding(GO:0001099)
0.0 0.5 GO:0004714 transmembrane receptor protein tyrosine kinase activity(GO:0004714)
0.0 0.0 GO:0016717 oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water(GO:0016717)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.0 0.0 PID MYC PATHWAY C-MYC pathway
0.0 0.4 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events
0.0 0.6 PID ECADHERIN STABILIZATION PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.0 0.0 PID FAS PATHWAY FAS (CD95) signaling pathway
0.0 0.6 NABA COLLAGENS Genes encoding collagen proteins
0.0 0.3 NABA BASEMENT MEMBRANES Genes encoding structural components of basement membranes

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 REACTOME SHC1 EVENTS IN EGFR SIGNALING Genes involved in SHC1 events in EGFR signaling
0.0 0.0 REACTOME PLC BETA MEDIATED EVENTS Genes involved in PLC beta mediated events
0.0 0.4 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.0 0.6 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.0 0.2 REACTOME PURINE CATABOLISM Genes involved in Purine catabolism
0.0 0.3 REACTOME SEROTONIN RECEPTORS Genes involved in Serotonin receptors
0.0 0.2 REACTOME G2 M DNA DAMAGE CHECKPOINT Genes involved in G2/M DNA damage checkpoint
0.0 0.1 REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.0 0.1 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
0.0 0.2 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.0 0.3 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.0 0.1 REACTOME CRMPS IN SEMA3A SIGNALING Genes involved in CRMPs in Sema3A signaling
0.0 0.8 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.0 0.2 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0 0.2 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0 0.3 REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.0 0.1 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.0 0.3 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.0 0.0 REACTOME PLATELET AGGREGATION PLUG FORMATION Genes involved in Platelet Aggregation (Plug Formation)
0.0 0.1 REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the late endosome membrane
0.0 0.0 REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY Genes involved in Regulation of the Fanconi anemia pathway
0.0 0.2 REACTOME SHC1 EVENTS IN ERBB4 SIGNALING Genes involved in SHC1 events in ERBB4 signaling
0.0 0.1 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.0 0.0 REACTOME ALPHA LINOLENIC ACID ALA METABOLISM Genes involved in alpha-linolenic acid (ALA) metabolism
0.0 0.1 REACTOME ERKS ARE INACTIVATED Genes involved in ERKs are inactivated
0.0 0.1 REACTOME NFKB IS ACTIVATED AND SIGNALS SURVIVAL Genes involved in NF-kB is activated and signals survival
0.0 0.2 REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Glutamate Neurotransmitter Release Cycle
0.0 0.1 REACTOME GAP JUNCTION DEGRADATION Genes involved in Gap junction degradation
0.0 0.3 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.0 0.1 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.0 0.1 REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters