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ENCODE: H3K4me1 ChIP-Seq of primary human cells

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Results for OSR1_OSR2

Z-value: 2.32

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Transcription factors associated with OSR1_OSR2

Gene Symbol	Gene ID	Gene Info
OSR1 Ensembl NCBI GeneCards UniProt	ENSG00000143867.5	odd-skipped related transcription factor 1
OSR2 Ensembl NCBI GeneCards UniProt	ENSG00000164920.5	odd-skipped related transciption factor 2

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE	Gene	Distance	Association probability	Pearson corr. coef.	P-value	Plot
chr2_19774448_19774599	OSR1	216109	0.022824	-0.95	1.0e-04	Click!
chr2_19740386_19740537	OSR1	182047	0.031101	-0.83	5.9e-03	Click!
chr2_19741188_19741339	OSR1	182849	0.030857	-0.83	6.0e-03	Click!
chr2_19738799_19738950	OSR1	180460	0.031590	-0.80	1.0e-02	Click!
chr2_19774735_19774886	OSR1	216396	0.022767	-0.77	1.5e-02	Click!
chr8_99975742_99975893	OSR2	15197	0.158561	-0.71	3.3e-02	Click!
chr8_99978768_99978919	OSR2	18223	0.152899	-0.71	3.4e-02	Click!
chr8_99957659_99957838	OSR2	861	0.552805	0.70	3.6e-02	Click!
chr8_99979066_99979217	OSR2	18521	0.152327	-0.68	4.4e-02	Click!
chr8_99957338_99957620	OSR2	592	0.695502	0.67	4.7e-02	Click!

Activity of the OSR1_OSR2 motif across conditions

Conditions sorted by the z-value of the OSR1_OSR2 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE)	Target Score	Top associated gene	Gene Info	Distance of CRE to TSS	CRE/Gene association probability
chr1_117056573_117057331	1.08	CD58	CD58 molecule	30260	0.14
chr5_150595265_150595488	1.03	GM2A	GM2 ganglioside activator	3665	0.22
chr11_117821389_117821783	0.98	TMPRSS13	transmembrane protease, serine 13	21412	0.15
chr1_185646518_185646683	0.92	ENSG00000201596	.	43286	0.15
chr14_61827530_61827767	0.92	PRKCH	protein kinase C, eta	144	0.97
chr22_40329879_40330140	0.91	GRAP2	GRB2-related adaptor protein 2	7368	0.18
chr5_67567518_67567669	0.90	PIK3R1	phosphoinositide-3-kinase, regulatory subunit 1 (alpha)	8475	0.29
chr7_50435924_50436099	0.90	ENSG00000200815	.	67067	0.11
chr2_241504090_241504573	0.89	RNPEPL1	arginyl aminopeptidase (aminopeptidase B)-like 1	890	0.44
chr13_77928416_77928623	0.89	MYCBP2	MYC binding protein 2, E3 ubiquitin protein ligase	27340	0.25
chr5_56137965_56138116	0.88	ENSG00000238717	.	14935	0.15
chr6_37475943_37476266	0.88	CCDC167	coiled-coil domain containing 167	8406	0.21
chr4_99584969_99585255	0.87	RP11-1299A16.3		5057	0.25
chr5_148415725_148415940	0.87	SH3TC2	SH3 domain and tetratricopeptide repeats 2	5277	0.19
chr12_44226149_44226476	0.86	TMEM117	transmembrane protein 117	3574	0.27
chr6_25008850_25009114	0.83	ENSG00000244618	.	22528	0.17
chr7_38348883_38349236	0.81	STARD3NL	STARD3 N-terminal like	131062	0.05
chr1_167602146_167602334	0.80	RP3-455J7.4		2329	0.28
chr14_102283672_102283878	0.80	CTD-2017C7.2		7117	0.15
chr6_91060753_91061282	0.78	ENSG00000266760	.	38556	0.18
chr14_91790763_91791635	0.78	ENSG00000265856	.	8858	0.21
chr14_38547457_38547608	0.76	CTD-2058B24.2		12831	0.26
chr15_73069226_73069377	0.76	ADPGK-AS1	ADPGK antisense RNA 1	5875	0.19
chr16_21659708_21660026	0.75	IGSF6	immunoglobulin superfamily, member 6	4060	0.14
chr16_68104442_68104656	0.75	NFATC3	nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3	14698	0.09
chr1_212968214_212968462	0.74	TATDN3	TatD DNase domain containing 3	313	0.88
chr2_240242275_240242517	0.74	HDAC4	histone deacetylase 4	11489	0.18
chr6_131526099_131526250	0.73	AKAP7	A kinase (PRKA) anchor protein 7	4207	0.36
chr16_3623403_3623748	0.73	NLRC3	NLR family, CARD domain containing 3	3817	0.17
chrX_78408330_78408687	0.73	GPR174	G protein-coupled receptor 174	17961	0.3
chr19_33651116_33651486	0.73	ENSG00000264355	.	16677	0.12
chr1_9485397_9485907	0.73	ENSG00000252956	.	12185	0.23
chr1_148195742_148195893	0.72	PPIAL4D	peptidylprolyl isomerase A (cyclophilin A)-like 4D	6719	0.26
chr1_8532692_8532843	0.72	ENSG00000221083	.	39211	0.15
chr1_14058388_14058781	0.72	PRDM2	PR domain containing 2, with ZNF domain	17314	0.21
chr16_68319061_68319396	0.72	ENSG00000252026	.	1007	0.3
chr22_37618057_37618806	0.71	SSTR3	somatostatin receptor 3	10069	0.13
chr6_147093114_147093265	0.71	ADGB	androglobin	1474	0.55
chr12_21766880_21767202	0.70	GYS2	glycogen synthase 2 (liver)	9260	0.2
chrX_147416060_147416261	0.70	AC002368.4		165975	0.04
chr2_240219157_240219354	0.70	ENSG00000265215	.	7902	0.19
chr2_143910577_143910744	0.69	RP11-190J23.1		19081	0.23
chr1_27156953_27157104	0.69	ZDHHC18	zinc finger, DHHC-type containing 18	1467	0.28
chr7_8004458_8004609	0.69	GLCCI1	glucocorticoid induced transcript 1	3892	0.21
chr15_60688902_60689138	0.69	ANXA2	annexin A2	517	0.85
chr5_150614598_150614909	0.69	CCDC69	coiled-coil domain containing 69	11047	0.18
chr2_69921039_69921201	0.69	ENSG00000238708	.	26629	0.17
chr15_38855420_38855571	0.69	RASGRP1	RAS guanyl releasing protein 1 (calcium and DAG-regulated)	1341	0.45
chr16_89794033_89794184	0.69	ZNF276	zinc finger protein 276	6156	0.1
chr13_22636687_22636838	0.69	ENSG00000244197	.	272086	0.02
chr17_55353882_55354230	0.68	MSI2	musashi RNA-binding protein 2	9149	0.28
chr12_112439406_112439724	0.68	TMEM116	transmembrane protein 116	4224	0.19
chr7_104985736_104986011	0.68	ENSG00000201179	.	12636	0.21
chr22_32538380_32538635	0.68	AP1B1P1	adaptor-related protein complex 1, beta 1 subunit pseudogene 1	10203	0.14
chr10_126418566_126418777	0.68	FAM53B	family with sequence similarity 53, member B	12868	0.17
chr13_49684512_49684663	0.67	FNDC3A	fibronectin type III domain containing 3A	138	0.97
chr22_25782802_25782953	0.67	LRP5L	low density lipoprotein receptor-related protein 5-like	5333	0.23
chr17_38760477_38760676	0.67	SMARCE1	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 1	27966	0.12
chr10_28909030_28909272	0.67	ENSG00000252401	.	32408	0.15
chr2_191281890_191282188	0.66	MFSD6	major facilitator superfamily domain containing 6	8958	0.2
chr4_166207034_166207185	0.66	ENSG00000200974	.	33377	0.15
chr10_28656205_28656487	0.66	MPP7	membrane protein, palmitoylated 7 (MAGUK p55 subfamily member 7)	32931	0.16
chr16_74642212_74642580	0.66	GLG1	golgi glycoprotein 1	1384	0.48
chr15_23027471_23027645	0.66	NIPA2	non imprinted in Prader-Willi/Angelman syndrome 2	6812	0.19
chr1_160674262_160674415	0.66	CD48	CD48 molecule	7255	0.16
chr7_106814622_106814964	0.66	HBP1	HMG-box transcription factor 1	4575	0.23
chr16_79302347_79302574	0.65	ENSG00000222244	.	4109	0.35
chr2_144049594_144049745	0.65	RP11-190J23.1		119928	0.06
chrX_71322805_71323092	0.65	RGAG4	retrotransposon gag domain containing 4	28730	0.14
chr1_111727930_111728149	0.64	RP5-1180E21.5		356	0.8
chr16_68272603_68272754	0.64	ESRP2	epithelial splicing regulatory protein 2	673	0.38
chr2_204596754_204596977	0.64	CD28	CD28 molecule	25449	0.18
chr1_25311538_25311783	0.64	RUNX3	runt-related transcription factor 3	20159	0.18
chr18_13437855_13438006	0.64	LDLRAD4-AS1	LDLRAD4 antisense RNA 1	10451	0.12
chr1_19806357_19806811	0.63	CAPZB	capping protein (actin filament) muscle Z-line, beta	3995	0.2
chr21_46341039_46341644	0.63	ITGB2-AS1	ITGB2 antisense RNA 1	100	0.73
chr10_48454539_48454690	0.63	GDF10	growth differentiation factor 10	15638	0.18
chr9_82220589_82220740	0.63	TLE4	transducin-like enhancer of split 4 (E(sp1) homolog, Drosophila)	32060	0.26
chr5_171551377_171551636	0.63	ENSG00000266671	.	43526	0.14
chr7_127440050_127440201	0.63	SND1	staphylococcal nuclease and tudor domain containing 1	87840	0.09
chr4_153380478_153380731	0.63	ENSG00000264678	.	29964	0.18
chr5_80036862_80037122	0.63	DHFR	dihydrofolate reductase	86190	0.08
chr6_36487291_36487442	0.63	ENSG00000239964	.	2602	0.21
chr1_117548818_117548969	0.63	CD101	CD101 molecule	4459	0.2
chr16_81503047_81503332	0.62	CMIP	c-Maf inducing protein	24414	0.23
chr19_1087607_1087865	0.62	POLR2E	polymerase (RNA) II (DNA directed) polypeptide E, 25kDa	7617	0.09
chr17_74139221_74139800	0.62	RNF157-AS1	RNF157 antisense RNA 1	1913	0.2
chr15_64919513_64919664	0.62	ENSG00000207223	.	25499	0.13
chr4_3197251_3197402	0.62	HTT	huntingtin	35237	0.17
chr15_38976198_38976376	0.62	C15orf53	chromosome 15 open reading frame 53	12512	0.28
chr1_160603209_160603365	0.62	SLAMF1	signaling lymphocytic activation molecule family member 1	13524	0.15
chrX_131618048_131618256	0.61	MBNL3	muscleblind-like splicing regulator 3	4891	0.32
chr11_81674020_81674171	0.61	ENSG00000264110	.	72217	0.14
chr10_135202816_135202986	0.61	RP11-108K14.8	Mitochondrial GTPase 1	1437	0.21
chr11_68097923_68098433	0.60	LRP5	low density lipoprotein receptor-related protein 5	18101	0.21
chrX_18588475_18588626	0.60	RS1	retinoschisin 1	101679	0.07
chr1_117101191_117101451	0.60	ENSG00000264419	.	1412	0.39
chr1_108492854_108493265	0.60	VAV3-AS1	VAV3 antisense RNA 1	14006	0.21
chr1_206747367_206748212	0.60	RASSF5	Ras association (RalGDS/AF-6) domain family member 5	17296	0.15
chr5_80300013_80300264	0.60	CTC-459I6.1		43412	0.16
chr6_35278431_35279308	0.60	DEF6	differentially expressed in FDCP 6 homolog (mouse)	1354	0.42
chr2_240152782_240153089	0.59	HDAC4	histone deacetylase 4	40183	0.13
chr11_34385617_34385918	0.59	ABTB2	ankyrin repeat and BTB (POZ) domain containing 2	6212	0.28
chr2_114457524_114457975	0.59	ENSG00000202427	.	19061	0.16
chr11_4090490_4090712	0.59	STIM1	stromal interaction molecule 1	5148	0.22
chr9_129285864_129286127	0.59	ENSG00000221768	.	7275	0.22
chr1_100913408_100913559	0.59	RP5-837M10.4		38070	0.16
chr1_112020337_112020708	0.59	C1orf162	chromosome 1 open reading frame 162	4031	0.12
chr3_4888757_4888908	0.59	ENSG00000239126	.	31554	0.17
chr14_92327065_92327275	0.59	TC2N	tandem C2 domains, nuclear	6703	0.21
chr17_2171475_2171819	0.58	SMG6	SMG6 nonsense mediated mRNA decay factor	2154	0.21
chr16_28209700_28209851	0.58	XPO6	exportin 6	13022	0.17
chr13_79975678_79975862	0.58	RBM26	RNA binding motif protein 26	4153	0.21
chr14_52784751_52784902	0.58	PTGER2	prostaglandin E receptor 2 (subtype EP2), 53kDa	3713	0.31
chr8_103810651_103810802	0.58	AZIN1	antizyme inhibitor 1	59604	0.1
chr5_118615599_118615750	0.58	TNFAIP8	tumor necrosis factor, alpha-induced protein 8	11225	0.18
chr6_112170750_112170901	0.58	FYN	FYN oncogene related to SRC, FGR, YES	3007	0.37
chr13_100035601_100035752	0.58	ENSG00000207719	.	27291	0.18
chr16_50304697_50304944	0.58	ADCY7	adenylate cyclase 7	3244	0.27
chr15_85303810_85304154	0.58	RP11-7M10.2		7629	0.15
chr19_54376046_54376205	0.58	MYADM	myeloid-associated differentiation marker	3106	0.09
chr1_118157265_118157675	0.58	FAM46C	family with sequence similarity 46, member C	8914	0.22
chr15_75090176_75090431	0.58	CSK	c-src tyrosine kinase	48	0.96
chr4_36327248_36327457	0.57	DTHD1	death domain containing 1	41708	0.17
chr17_78846780_78847058	0.57	RPTOR	regulatory associated protein of MTOR, complex 1	49605	0.11
chrX_129222301_129222452	0.57	ELF4	E74-like factor 4 (ets domain transcription factor)	21960	0.19
chr14_36235989_36236257	0.57	ENSG00000253059	.	10590	0.16
chr4_166215238_166215389	0.57	MSMO1	methylsterol monooxygenase 1	33462	0.15
chr15_34620468_34620619	0.57	SLC12A6	solute carrier family 12 (potassium/chloride transporter), member 6	8502	0.12
chrX_70328164_70328598	0.57	IL2RG	interleukin 2 receptor, gamma	737	0.47
chr1_111186012_111186163	0.56	ENSG00000221538	.	9566	0.18
chr8_125499989_125500140	0.56	RP11-158K1.3		687	0.64
chr11_45047514_45047716	0.56	PRDM11	PR domain containing 11	67949	0.12
chr12_92796420_92796828	0.56	RP11-693J15.4		18683	0.18
chr15_60877657_60877957	0.56	RORA	RAR-related orphan receptor A	6933	0.24
chr1_112190134_112190365	0.56	ENSG00000201028	.	2910	0.25
chrX_13016516_13016803	0.56	TMSB4X	thymosin beta 4, X-linked	22882	0.2
chr16_3917043_3917313	0.56	CREBBP	CREB binding protein	12943	0.21
chr7_148544637_148544788	0.56	ENSG00000251712	.	26608	0.14
chr11_128644504_128644655	0.56	FLI1	Fli-1 proto-oncogene, ETS transcription factor	9894	0.22
chr4_15609696_15609847	0.56	FBXL5	F-box and leucine-rich repeat protein 5	36501	0.15
chr12_51718815_51719232	0.55	BIN2	bridging integrator 2	571	0.71
chrX_71336501_71336652	0.55	RGAG4	retrotransposon gag domain containing 4	15102	0.16
chr6_11710027_11710178	0.55	ENSG00000207419	.	50	0.98
chr8_6582802_6582976	0.55	AGPAT5	1-acylglycerol-3-phosphate O-acyltransferase 5	16675	0.17
chr19_8813606_8813968	0.55	ACTL9	actin-like 9	4615	0.22
chr14_91877682_91877988	0.55	CCDC88C	coiled-coil domain containing 88C	5855	0.26
chr8_19553467_19553618	0.55	CSGALNACT1	chondroitin sulfate N-acetylgalactosaminyltransferase 1	13270	0.29
chr17_74175074_74175225	0.55	RNF157	ring finger protein 157	11986	0.13
chr7_36663254_36663529	0.55	ENSG00000221561	.	18458	0.18
chr6_139572992_139573163	0.54	TXLNB	taxilin beta	10657	0.19
chr1_11307359_11307510	0.54	MTOR	mechanistic target of rapamycin (serine/threonine kinase)	15130	0.14
chr10_11236679_11236947	0.54	RP3-323N1.2		23474	0.2
chr13_77312950_77313101	0.54	KCTD12	potassium channel tetramerization domain containing 12	147500	0.04
chr16_50801742_50801950	0.54	CYLD	cylindromatosis (turban tumor syndrome)	18386	0.11
chr1_26441433_26441584	0.54	PDIK1L	PDLIM1 interacting kinase 1 like	3168	0.15
chr2_171508638_171509172	0.54	AC007277.3		8451	0.23
chr22_23207531_23207682	0.54	IGLV4-3	immunoglobulin lambda variable 4-3	6080	0.05
chr4_128554514_128554677	0.54	INTU	inturned planar cell polarity protein	475	0.88
chr5_75840980_75841213	0.53	IQGAP2	IQ motif containing GTPase activating protein 2	2138	0.39
chr7_55541540_55541796	0.53	VOPP1	vesicular, overexpressed in cancer, prosurvival protein 1	42102	0.18
chr3_108551834_108551998	0.53	TRAT1	T cell receptor associated transmembrane adaptor 1	10297	0.26
chr14_93120739_93120918	0.53	RIN3	Ras and Rab interactor 3	1982	0.44
chr8_128192126_128192325	0.53	POU5F1B	POU class 5 homeobox 1B	234310	0.02
chr10_103815226_103815416	0.53	C10orf76	chromosome 10 open reading frame 76	629	0.68
chr4_109081453_109081912	0.53	LEF1	lymphoid enhancer-binding factor 1	5775	0.24
chr10_50397490_50397641	0.52	C10orf128	chromosome 10 open reading frame 128	1129	0.52
chr4_144325483_144325634	0.52	GAB1	GRB2-associated binding protein 1	12895	0.23
chr5_49624115_49624266	0.52	EMB	embigin	100371	0.09
chr6_130537662_130538085	0.52	SAMD3	sterile alpha motif domain containing 3	794	0.75
chr22_39545331_39545521	0.52	CBX7	chromobox homolog 7	3023	0.22
chr20_51610177_51610328	0.52	TSHZ2	teashirt zinc finger homeobox 2	21306	0.24
chrX_78413004_78413155	0.52	GPR174	G protein-coupled receptor 174	13390	0.31
chr7_150705681_150705832	0.52	NOS3	nitric oxide synthase 3 (endothelial cell)	269	0.84
chr22_40305396_40305614	0.52	GRAP2	GRB2-related adaptor protein 2	8392	0.18
chr2_88327551_88327940	0.52	ENSG00000222724	.	11679	0.14
chr2_232410029_232410622	0.52	NMUR1	neuromedin U receptor 1	15119	0.14
chr2_106804645_106804858	0.52	UXS1	UDP-glucuronate decarboxylase 1	6004	0.25
chr22_40484830_40485057	0.52	TNRC6B	trinucleotide repeat containing 6B	43465	0.14
chr1_67677903_67678054	0.52	IL23R	interleukin 23 receptor	4629	0.17
chr1_8683787_8683941	0.52	RERE	arginine-glutamic acid dipeptide (RE) repeats	575	0.83
chr10_111929980_111930210	0.52	MXI1	MAX interactor 1, dimerization protein	37268	0.17
chr5_112354195_112354393	0.52	DCP2	decapping mRNA 2	41815	0.16
chr17_73396861_73397043	0.51	GRB2	growth factor receptor-bound protein 2	4615	0.1
chr2_136893266_136893435	0.51	CXCR4	chemokine (C-X-C motif) receptor 4	17615	0.27
chr4_90166750_90166901	0.51	GPRIN3	GPRIN family member 3	5520	0.31
chr3_111264164_111264389	0.51	CD96	CD96 molecule	3279	0.32
chrX_101914217_101914428	0.51	RP4-769N13.7		318	0.86
chrX_11779477_11779642	0.51	MSL3	male-specific lethal 3 homolog (Drosophila)	1812	0.5
chr1_25992814_25992965	0.51	RP1-187B23.1		7287	0.2
chr8_49862673_49862887	0.51	SNAI2	snail family zinc finger 2	28481	0.25
chr3_69106553_69106704	0.51	TMF1	TATA element modulatory factor 1	5144	0.15
chr5_75701847_75702137	0.51	IQGAP2	IQ motif containing GTPase activating protein 2	1743	0.49
chr6_152024316_152024467	0.51	ESR1	estrogen receptor 1	12760	0.26
chr11_85763685_85763836	0.51	PICALM	phosphatidylinositol binding clathrin assembly protein	16062	0.21
chr7_4725664_4725895	0.51	ENSG00000238781	.	3332	0.25
chr3_186743418_186743719	0.51	ST6GAL1	ST6 beta-galactosamide alpha-2,6-sialyltranferase 1	297	0.93
chrX_128911606_128911929	0.51	SASH3	SAM and SH3 domain containing 3	2193	0.32
chr3_32345545_32345886	0.51	ENSG00000207857	.	44495	0.14
chr4_54277446_54277597	0.51	FIP1L1	factor interacting with PAPOLA and CPSF1	16712	0.22

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of OSR1_OSR2

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.3	0.8	GO:0048742	regulation of skeletal muscle fiber development(GO:0048742)
0.2	0.8	GO:0030854	positive regulation of granulocyte differentiation(GO:0030854)
0.2	0.7	GO:1901339	activation of store-operated calcium channel activity(GO:0032237) regulation of store-operated calcium channel activity(GO:1901339) positive regulation of store-operated calcium channel activity(GO:1901341)
0.2	0.6	GO:0031340	positive regulation of vesicle fusion(GO:0031340)
0.1	0.4	GO:0046449	allantoin metabolic process(GO:0000255) creatinine metabolic process(GO:0046449) cellular lactam metabolic process(GO:0072338)
0.1	0.4	GO:0071224	cellular response to peptidoglycan(GO:0071224)
0.1	0.4	GO:0034638	phosphatidylcholine catabolic process(GO:0034638)
0.1	0.3	GO:0045341	MHC class I biosynthetic process(GO:0045341) regulation of MHC class I biosynthetic process(GO:0045343)
0.1	0.6	GO:0031061	negative regulation of histone methylation(GO:0031061)
0.1	0.5	GO:0045589	regulation of regulatory T cell differentiation(GO:0045589)
0.1	0.1	GO:0002677	negative regulation of chronic inflammatory response(GO:0002677)
0.1	0.5	GO:0009313	oligosaccharide catabolic process(GO:0009313)
0.1	0.4	GO:0003056	regulation of vascular smooth muscle contraction(GO:0003056)
0.1	0.1	GO:0006269	DNA replication, synthesis of RNA primer(GO:0006269)
0.1	1.0	GO:0002507	tolerance induction(GO:0002507)
0.1	0.3	GO:0031946	regulation of glucocorticoid biosynthetic process(GO:0031946)
0.1	0.2	GO:0046642	negative regulation of alpha-beta T cell proliferation(GO:0046642)
0.1	0.3	GO:0010956	negative regulation of calcidiol 1-monooxygenase activity(GO:0010956) negative regulation of vitamin D biosynthetic process(GO:0010957) negative regulation of vitamin metabolic process(GO:0046137)
0.1	0.3	GO:0042091	interleukin-10 biosynthetic process(GO:0042091) regulation of interleukin-10 biosynthetic process(GO:0045074)
0.1	0.4	GO:0031282	regulation of guanylate cyclase activity(GO:0031282)
0.1	0.5	GO:0050857	positive regulation of antigen receptor-mediated signaling pathway(GO:0050857)
0.1	0.2	GO:0010572	positive regulation of platelet activation(GO:0010572)
0.1	1.1	GO:0006607	NLS-bearing protein import into nucleus(GO:0006607)
0.1	0.3	GO:0010459	negative regulation of heart rate(GO:0010459)
0.1	0.3	GO:0001766	membrane raft polarization(GO:0001766) membrane raft distribution(GO:0031580)
0.1	0.3	GO:0006089	lactate metabolic process(GO:0006089)
0.1	0.2	GO:0045066	regulatory T cell differentiation(GO:0045066)
0.1	0.5	GO:0060009	Sertoli cell development(GO:0060009)
0.1	0.3	GO:0035066	positive regulation of histone acetylation(GO:0035066) positive regulation of protein acetylation(GO:1901985) positive regulation of peptidyl-lysine acetylation(GO:2000758)
0.1	0.3	GO:0035610	C-terminal protein deglutamylation(GO:0035609) protein side chain deglutamylation(GO:0035610)
0.1	0.3	GO:0007042	lysosomal lumen acidification(GO:0007042) regulation of lysosomal lumen pH(GO:0035751)
0.1	0.6	GO:0001562	response to protozoan(GO:0001562)
0.1	1.0	GO:0032653	regulation of interleukin-10 production(GO:0032653)
0.1	0.2	GO:0019276	UDP-N-acetylgalactosamine metabolic process(GO:0019276)
0.1	0.1	GO:0010915	regulation of very-low-density lipoprotein particle clearance(GO:0010915) negative regulation of very-low-density lipoprotein particle clearance(GO:0010916)
0.1	0.2	GO:0046548	retinal rod cell development(GO:0046548)
0.1	0.2	GO:0006610	ribosomal protein import into nucleus(GO:0006610)
0.1	0.2	GO:0015917	aminophospholipid transport(GO:0015917)
0.1	0.4	GO:0007172	signal complex assembly(GO:0007172)
0.1	0.1	GO:0003100	regulation of systemic arterial blood pressure by endothelin(GO:0003100)
0.1	0.1	GO:0032814	regulation of natural killer cell activation(GO:0032814)
0.1	0.1	GO:0061030	epithelial cell differentiation involved in mammary gland alveolus development(GO:0061030)
0.1	0.2	GO:0045163	clustering of voltage-gated potassium channels(GO:0045163)
0.1	0.3	GO:0034755	iron ion transmembrane transport(GO:0034755)
0.1	0.1	GO:0034983	peptidyl-lysine deacetylation(GO:0034983)
0.1	0.3	GO:0042989	sequestering of actin monomers(GO:0042989)
0.1	0.5	GO:0051491	positive regulation of filopodium assembly(GO:0051491)
0.1	0.2	GO:0034626	fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.1	0.1	GO:0014742	positive regulation of cardiac muscle hypertrophy(GO:0010613) positive regulation of muscle hypertrophy(GO:0014742)
0.1	0.2	GO:0048478	replication fork protection(GO:0048478)
0.1	0.3	GO:0045056	transcytosis(GO:0045056)
0.1	0.6	GO:0006906	vesicle fusion(GO:0006906)
0.1	0.2	GO:0042420	dopamine catabolic process(GO:0042420)
0.1	0.4	GO:0008653	lipopolysaccharide metabolic process(GO:0008653)
0.1	0.1	GO:0048541	Peyer's patch development(GO:0048541)
0.1	0.2	GO:0006007	glucose catabolic process(GO:0006007)
0.1	0.8	GO:0000305	response to oxygen radical(GO:0000305)
0.1	0.2	GO:1901978	positive regulation of spindle checkpoint(GO:0090232) regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090266) positive regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090267) positive regulation of cell cycle checkpoint(GO:1901978) regulation of mitotic spindle checkpoint(GO:1903504)
0.1	0.2	GO:0001787	natural killer cell proliferation(GO:0001787)
0.1	0.2	GO:0002407	dendritic cell chemotaxis(GO:0002407) dendritic cell migration(GO:0036336)
0.1	0.1	GO:0030223	neutrophil differentiation(GO:0030223)
0.1	0.4	GO:0050858	negative regulation of antigen receptor-mediated signaling pathway(GO:0050858) negative regulation of T cell receptor signaling pathway(GO:0050860)
0.1	3.5	GO:0050852	T cell receptor signaling pathway(GO:0050852)
0.1	0.2	GO:0035405	histone-threonine phosphorylation(GO:0035405)
0.1	0.2	GO:0070102	interleukin-6-mediated signaling pathway(GO:0070102)
0.1	0.2	GO:0003078	obsolete regulation of natriuresis(GO:0003078)
0.1	0.2	GO:0045654	positive regulation of megakaryocyte differentiation(GO:0045654) positive regulation of hematopoietic progenitor cell differentiation(GO:1901534)
0.1	0.1	GO:0045986	negative regulation of smooth muscle contraction(GO:0045986)
0.1	0.2	GO:0043320	natural killer cell activation involved in immune response(GO:0002323) natural killer cell degranulation(GO:0043320)
0.1	0.2	GO:0071921	establishment of sister chromatid cohesion(GO:0034085) cohesin loading(GO:0071921) regulation of cohesin loading(GO:0071922)
0.1	0.2	GO:0006678	glucosylceramide metabolic process(GO:0006678)
0.1	0.1	GO:1903053	regulation of extracellular matrix disassembly(GO:0010715) negative regulation of extracellular matrix disassembly(GO:0010716) regulation of extracellular matrix organization(GO:1903053) negative regulation of extracellular matrix organization(GO:1903054)
0.1	0.2	GO:0033152	immunoglobulin V(D)J recombination(GO:0033152)
0.1	0.6	GO:0070536	protein K63-linked deubiquitination(GO:0070536)
0.1	0.1	GO:0032071	regulation of endodeoxyribonuclease activity(GO:0032071)
0.1	0.2	GO:0042339	keratan sulfate metabolic process(GO:0042339)
0.1	0.2	GO:0001821	histamine secretion(GO:0001821)
0.1	0.1	GO:0002888	positive regulation of myeloid leukocyte mediated immunity(GO:0002888)
0.0	0.1	GO:0000733	DNA strand renaturation(GO:0000733)
0.0	0.1	GO:0045416	positive regulation of interleukin-8 biosynthetic process(GO:0045416)
0.0	0.2	GO:0043984	histone H4-K16 acetylation(GO:0043984)
0.0	0.1	GO:0018076	N-terminal peptidyl-lysine acetylation(GO:0018076)
0.0	0.2	GO:0007256	activation of JNKK activity(GO:0007256)
0.0	0.0	GO:0032509	endosome transport via multivesicular body sorting pathway(GO:0032509)
0.0	0.7	GO:0050832	defense response to fungus(GO:0050832)
0.0	0.2	GO:0043951	negative regulation of cAMP-mediated signaling(GO:0043951)
0.0	0.1	GO:0002523	leukocyte migration involved in inflammatory response(GO:0002523)
0.0	0.1	GO:0046398	UDP-glucuronate metabolic process(GO:0046398)
0.0	0.1	GO:0042663	endodermal cell fate specification(GO:0001714) regulation of endodermal cell fate specification(GO:0042663) regulation of endodermal cell differentiation(GO:1903224)
0.0	0.1	GO:0090075	relaxation of muscle(GO:0090075)
0.0	0.0	GO:0032278	positive regulation of gonadotropin secretion(GO:0032278) positive regulation of follicle-stimulating hormone secretion(GO:0046881)
0.0	0.5	GO:0016045	detection of bacterium(GO:0016045)
0.0	0.0	GO:0090205	positive regulation of cholesterol metabolic process(GO:0090205)
0.0	0.4	GO:0036230	granulocyte activation(GO:0036230)
0.0	0.0	GO:0046007	negative regulation of activated T cell proliferation(GO:0046007)
0.0	0.0	GO:0045759	negative regulation of action potential(GO:0045759)
0.0	0.1	GO:0034219	carbohydrate transmembrane transport(GO:0034219)
0.0	0.1	GO:0033345	asparagine catabolic process(GO:0006530) asparagine catabolic process via L-aspartate(GO:0033345)
0.0	0.1	GO:0051657	maintenance of organelle location(GO:0051657)
0.0	0.1	GO:0050955	thermoception(GO:0050955)
0.0	0.3	GO:0001782	B cell homeostasis(GO:0001782)
0.0	0.2	GO:0015760	hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760)
0.0	0.1	GO:0060528	secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development(GO:0060528)
0.0	0.0	GO:0016080	synaptic vesicle targeting(GO:0016080)
0.0	0.1	GO:0006106	fumarate metabolic process(GO:0006106)
0.0	0.0	GO:0035987	endodermal cell fate commitment(GO:0001711) endodermal cell differentiation(GO:0035987)
0.0	0.2	GO:0055064	cellular chloride ion homeostasis(GO:0030644) chloride ion homeostasis(GO:0055064)
0.0	0.1	GO:0045085	negative regulation of interleukin-2 biosynthetic process(GO:0045085)
0.0	0.0	GO:0030889	negative regulation of B cell proliferation(GO:0030889)
0.0	0.0	GO:0010831	positive regulation of myotube differentiation(GO:0010831)
0.0	0.0	GO:0051152	positive regulation of smooth muscle cell differentiation(GO:0051152)
0.0	0.1	GO:0046940	nucleoside monophosphate phosphorylation(GO:0046940)
0.0	0.1	GO:0016103	diterpenoid catabolic process(GO:0016103) terpenoid catabolic process(GO:0016115) retinoic acid catabolic process(GO:0034653)
0.0	0.2	GO:0042362	fat-soluble vitamin biosynthetic process(GO:0042362)
0.0	0.0	GO:0044252	negative regulation of collagen metabolic process(GO:0010713) negative regulation of collagen biosynthetic process(GO:0032966) negative regulation of multicellular organismal metabolic process(GO:0044252)
0.0	0.2	GO:0002483	antigen processing and presentation of endogenous peptide antigen(GO:0002483) antigen processing and presentation of endogenous peptide antigen via MHC class I(GO:0019885)
0.0	0.1	GO:0035455	response to interferon-alpha(GO:0035455)
0.0	0.1	GO:0009048	dosage compensation by inactivation of X chromosome(GO:0009048)
0.0	0.7	GO:0035116	embryonic hindlimb morphogenesis(GO:0035116)
0.0	0.1	GO:0048387	negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.0	0.1	GO:0071392	cellular response to estradiol stimulus(GO:0071392)
0.0	0.1	GO:0006384	transcription initiation from RNA polymerase III promoter(GO:0006384)
0.0	0.2	GO:0030910	olfactory placode formation(GO:0030910) olfactory placode development(GO:0071698) olfactory placode morphogenesis(GO:0071699)
0.0	0.0	GO:0051608	histamine transport(GO:0051608)
0.0	0.2	GO:0046874	quinolinate metabolic process(GO:0046874)
0.0	0.1	GO:0070779	D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
0.0	0.3	GO:0030206	chondroitin sulfate biosynthetic process(GO:0030206)
0.0	0.0	GO:0071481	cellular response to X-ray(GO:0071481)
0.0	0.2	GO:0048096	chromatin-mediated maintenance of transcription(GO:0048096)
0.0	0.5	GO:0045576	mast cell activation(GO:0045576)
0.0	0.2	GO:2000258	negative regulation of complement activation(GO:0045916) negative regulation of protein activation cascade(GO:2000258)
0.0	0.0	GO:1901522	positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus(GO:1901522)
0.0	0.1	GO:0045722	positive regulation of gluconeogenesis(GO:0045722)
0.0	0.4	GO:0043508	negative regulation of JUN kinase activity(GO:0043508)
0.0	0.1	GO:0042726	flavin-containing compound metabolic process(GO:0042726)
0.0	0.4	GO:0045197	establishment or maintenance of epithelial cell apical/basal polarity(GO:0045197)
0.0	0.4	GO:0019059	obsolete initiation of viral infection(GO:0019059)
0.0	0.1	GO:0035092	sperm chromatin condensation(GO:0035092)
0.0	0.3	GO:0031146	SCF-dependent proteasomal ubiquitin-dependent protein catabolic process(GO:0031146)
0.0	0.6	GO:0032012	regulation of ARF protein signal transduction(GO:0032012)
0.0	0.1	GO:0006154	adenosine catabolic process(GO:0006154)
0.0	0.3	GO:0006978	DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:0006978)
0.0	0.6	GO:0034199	activation of protein kinase A activity(GO:0034199)
0.0	0.4	GO:0050851	antigen receptor-mediated signaling pathway(GO:0050851)
0.0	0.2	GO:0045885	obsolete positive regulation of survival gene product expression(GO:0045885)
0.0	0.4	GO:0001954	positive regulation of cell-matrix adhesion(GO:0001954)
0.0	0.2	GO:0006030	chitin metabolic process(GO:0006030) chitin catabolic process(GO:0006032)
0.0	0.7	GO:0006691	leukotriene metabolic process(GO:0006691)
0.0	0.1	GO:0051461	corticotropin secretion(GO:0051458) regulation of corticotropin secretion(GO:0051459) positive regulation of corticotropin secretion(GO:0051461)
0.0	0.0	GO:0015014	heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.0	0.2	GO:0032875	regulation of DNA endoreduplication(GO:0032875) negative regulation of DNA endoreduplication(GO:0032876) DNA endoreduplication(GO:0042023)
0.0	0.1	GO:0035025	positive regulation of Rho protein signal transduction(GO:0035025)
0.0	0.1	GO:0007064	mitotic sister chromatid cohesion(GO:0007064)
0.0	0.1	GO:0019042	viral latency(GO:0019042)
0.0	0.1	GO:0009138	pyrimidine nucleoside diphosphate metabolic process(GO:0009138)
0.0	0.0	GO:0019372	lipoxygenase pathway(GO:0019372)
0.0	0.9	GO:0043484	regulation of RNA splicing(GO:0043484)
0.0	0.0	GO:0050765	negative regulation of phagocytosis(GO:0050765)
0.0	0.3	GO:0098927	early endosome to late endosome transport(GO:0045022) vesicle-mediated transport between endosomal compartments(GO:0098927)
0.0	0.1	GO:0019441	tryptophan catabolic process to kynurenine(GO:0019441)
0.0	0.1	GO:0043518	negative regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043518) negative regulation of signal transduction by p53 class mediator(GO:1901797)
0.0	0.1	GO:0045059	positive thymic T cell selection(GO:0045059)
0.0	0.3	GO:0006491	N-glycan processing(GO:0006491)
0.0	0.3	GO:0043029	T cell homeostasis(GO:0043029)
0.0	0.1	GO:0006104	succinyl-CoA metabolic process(GO:0006104)
0.0	0.1	GO:0006003	fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.0	0.2	GO:0045116	protein neddylation(GO:0045116)
0.0	0.7	GO:0006611	protein export from nucleus(GO:0006611)
0.0	0.0	GO:0045906	negative regulation of vasoconstriction(GO:0045906)
0.0	0.1	GO:0015816	glycine transport(GO:0015816)
0.0	0.4	GO:0045730	respiratory burst(GO:0045730)
0.0	0.2	GO:0048679	regulation of axon regeneration(GO:0048679) regulation of neuron projection regeneration(GO:0070570)
0.0	0.2	GO:0022614	membrane to membrane docking(GO:0022614)
0.0	0.3	GO:0002286	T cell activation involved in immune response(GO:0002286)
0.0	0.1	GO:0043619	regulation of transcription from RNA polymerase II promoter in response to oxidative stress(GO:0043619)
0.0	0.1	GO:0006422	aspartyl-tRNA aminoacylation(GO:0006422)
0.0	0.4	GO:0031648	protein destabilization(GO:0031648)
0.0	0.0	GO:0043570	maintenance of DNA repeat elements(GO:0043570)
0.0	0.0	GO:0051489	regulation of filopodium assembly(GO:0051489)
0.0	0.1	GO:0070837	dehydroascorbic acid transport(GO:0070837)
0.0	0.0	GO:0032785	negative regulation of DNA-templated transcription, elongation(GO:0032785) negative regulation of transcription elongation from RNA polymerase II promoter(GO:0034244)
0.0	0.1	GO:0006167	AMP biosynthetic process(GO:0006167)
0.0	0.1	GO:0046831	regulation of RNA export from nucleus(GO:0046831)
0.0	0.2	GO:0045717	negative regulation of fatty acid biosynthetic process(GO:0045717)
0.0	0.0	GO:0010979	regulation of vitamin D 24-hydroxylase activity(GO:0010979) positive regulation of vitamin D 24-hydroxylase activity(GO:0010980)
0.0	0.1	GO:0048711	positive regulation of astrocyte differentiation(GO:0048711)
0.0	0.2	GO:0050957	equilibrioception(GO:0050957)
0.0	0.1	GO:0006642	triglyceride mobilization(GO:0006642)
0.0	0.1	GO:0045824	negative regulation of innate immune response(GO:0045824)
0.0	0.1	GO:0045990	carbon catabolite regulation of transcription(GO:0045990) regulation of transcription by glucose(GO:0046015)
0.0	0.1	GO:0045006	DNA deamination(GO:0045006)
0.0	0.2	GO:0045910	negative regulation of DNA recombination(GO:0045910)
0.0	0.0	GO:0052555	positive regulation by organism of immune response of other organism involved in symbiotic interaction(GO:0052555) positive regulation by symbiont of host immune response(GO:0052556)
0.0	0.1	GO:0046877	regulation of saliva secretion(GO:0046877)
0.0	0.1	GO:0009106	lipoate metabolic process(GO:0009106)
0.0	0.0	GO:0033131	regulation of glucokinase activity(GO:0033131) positive regulation of glucokinase activity(GO:0033133) regulation of hexokinase activity(GO:1903299) positive regulation of hexokinase activity(GO:1903301)
0.0	0.1	GO:0006772	thiamine metabolic process(GO:0006772)
0.0	0.7	GO:0031294	lymphocyte costimulation(GO:0031294) T cell costimulation(GO:0031295)
0.0	0.0	GO:0060397	JAK-STAT cascade involved in growth hormone signaling pathway(GO:0060397)
0.0	0.1	GO:0070672	response to interleukin-15(GO:0070672)
0.0	0.1	GO:0017183	peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183)
0.0	0.1	GO:0050774	negative regulation of dendrite morphogenesis(GO:0050774)
0.0	0.2	GO:0030851	granulocyte differentiation(GO:0030851)
0.0	0.2	GO:0006621	protein retention in ER lumen(GO:0006621) maintenance of protein localization in endoplasmic reticulum(GO:0035437)
0.0	0.4	GO:0045646	regulation of erythrocyte differentiation(GO:0045646)
0.0	0.1	GO:0032506	cytokinetic process(GO:0032506)
0.0	0.0	GO:0090231	regulation of spindle checkpoint(GO:0090231)
0.0	0.0	GO:0052251	induction by organism of defense response of other organism involved in symbiotic interaction(GO:0052251)
0.0	0.1	GO:0033158	regulation of protein import into nucleus, translocation(GO:0033158)
0.0	0.1	GO:0006474	N-terminal protein amino acid acetylation(GO:0006474)
0.0	0.5	GO:0043124	negative regulation of I-kappaB kinase/NF-kappaB signaling(GO:0043124)
0.0	0.1	GO:0032328	alanine transport(GO:0032328)
0.0	0.1	GO:0052805	histidine catabolic process(GO:0006548) imidazole-containing compound catabolic process(GO:0052805)
0.0	0.2	GO:0045540	regulation of cholesterol biosynthetic process(GO:0045540)
0.0	0.1	GO:1901419	regulation of response to alcohol(GO:1901419)
0.0	0.1	GO:0045071	negative regulation of viral genome replication(GO:0045071)
0.0	0.1	GO:0040016	embryonic cleavage(GO:0040016)
0.0	0.1	GO:0051971	positive regulation of transmission of nerve impulse(GO:0051971)
0.0	0.1	GO:0007023	post-chaperonin tubulin folding pathway(GO:0007023)
0.0	0.0	GO:0034122	negative regulation of toll-like receptor signaling pathway(GO:0034122)
0.0	0.0	GO:0001973	adenosine receptor signaling pathway(GO:0001973) G-protein coupled purinergic receptor signaling pathway(GO:0035588)
0.0	0.2	GO:0016556	mRNA modification(GO:0016556)
0.0	0.0	GO:0032682	negative regulation of chemokine production(GO:0032682) negative regulation of chemokine biosynthetic process(GO:0045079)
0.0	0.0	GO:0048563	post-embryonic organ morphogenesis(GO:0048563)
0.0	0.3	GO:0071514	genetic imprinting(GO:0071514)
0.0	0.0	GO:0042789	mRNA transcription from RNA polymerase II promoter(GO:0042789)
0.0	0.2	GO:0006241	GTP biosynthetic process(GO:0006183) UTP biosynthetic process(GO:0006228) CTP biosynthetic process(GO:0006241) pyrimidine ribonucleoside triphosphate metabolic process(GO:0009208) pyrimidine ribonucleoside triphosphate biosynthetic process(GO:0009209) CTP metabolic process(GO:0046036) UTP metabolic process(GO:0046051)
0.0	0.0	GO:0002495	antigen processing and presentation of peptide antigen via MHC class II(GO:0002495)
0.0	0.0	GO:0008054	negative regulation of cyclin-dependent protein serine/threonine kinase by cyclin degradation(GO:0008054)
0.0	0.0	GO:0007262	STAT protein import into nucleus(GO:0007262)
0.0	0.1	GO:0006685	sphingomyelin catabolic process(GO:0006685)
0.0	0.1	GO:0051294	establishment of mitotic spindle orientation(GO:0000132) establishment of spindle orientation(GO:0051294)
0.0	0.1	GO:0010815	bradykinin catabolic process(GO:0010815)
0.0	0.1	GO:0008298	intracellular mRNA localization(GO:0008298)
0.0	0.1	GO:0017085	response to insecticide(GO:0017085)
0.0	0.1	GO:0042866	pyruvate biosynthetic process(GO:0042866)
0.0	0.1	GO:0003214	cardiac left ventricle morphogenesis(GO:0003214)
0.0	0.0	GO:2001012	mesenchymal cell differentiation involved in kidney development(GO:0072161) metanephric mesenchymal cell differentiation(GO:0072162) mesenchymal cell differentiation involved in renal system development(GO:2001012)
0.0	0.0	GO:0045292	mRNA cis splicing, via spliceosome(GO:0045292)
0.0	0.5	GO:0008630	intrinsic apoptotic signaling pathway in response to DNA damage(GO:0008630)
0.0	0.0	GO:2000399	negative regulation of T cell differentiation in thymus(GO:0033085) negative regulation of thymocyte aggregation(GO:2000399)
0.0	0.3	GO:0046834	lipid phosphorylation(GO:0046834)
0.0	0.1	GO:0032486	Rap protein signal transduction(GO:0032486)
0.0	0.1	GO:0034501	protein localization to kinetochore(GO:0034501)
0.0	1.5	GO:0006959	humoral immune response(GO:0006959)
0.0	0.0	GO:0032959	inositol trisphosphate biosynthetic process(GO:0032959)
0.0	0.3	GO:0060334	regulation of response to interferon-gamma(GO:0060330) regulation of interferon-gamma-mediated signaling pathway(GO:0060334)
0.0	0.2	GO:0050927	positive regulation of positive chemotaxis(GO:0050927)
0.0	0.1	GO:0006198	cAMP catabolic process(GO:0006198)
0.0	0.1	GO:0002076	osteoblast development(GO:0002076)
0.0	0.1	GO:0033522	histone H2A ubiquitination(GO:0033522)
0.0	0.0	GO:0071364	cellular response to epidermal growth factor stimulus(GO:0071364)
0.0	0.1	GO:0048714	positive regulation of oligodendrocyte differentiation(GO:0048714)
0.0	0.1	GO:0060219	camera-type eye photoreceptor cell differentiation(GO:0060219)
0.0	0.1	GO:0015791	polyol transport(GO:0015791)
0.0	0.1	GO:0006102	isocitrate metabolic process(GO:0006102)
0.0	0.0	GO:0002862	negative regulation of inflammatory response to antigenic stimulus(GO:0002862)
0.0	0.1	GO:0046835	carbohydrate phosphorylation(GO:0046835)
0.0	0.1	GO:0032988	ribonucleoprotein complex disassembly(GO:0032988)
0.0	0.0	GO:0019532	oxalate transport(GO:0019532)
0.0	0.1	GO:0051290	protein heterotetramerization(GO:0051290)
0.0	0.1	GO:0032715	negative regulation of interleukin-6 production(GO:0032715)
0.0	0.1	GO:0033687	osteoblast proliferation(GO:0033687)
0.0	0.1	GO:0006013	mannose metabolic process(GO:0006013)
0.0	0.1	GO:0000185	activation of MAPKKK activity(GO:0000185)
0.0	0.0	GO:0061154	endothelial tube morphogenesis(GO:0061154)
0.0	0.1	GO:0031440	regulation of mRNA 3'-end processing(GO:0031440) positive regulation of mRNA 3'-end processing(GO:0031442) positive regulation of mRNA processing(GO:0050685) positive regulation of mRNA metabolic process(GO:1903313)
0.0	0.2	GO:0051568	histone H3-K4 methylation(GO:0051568)
0.0	0.0	GO:0002438	acute inflammatory response to antigenic stimulus(GO:0002438)
0.0	0.6	GO:0000245	spliceosomal complex assembly(GO:0000245)
0.0	0.0	GO:0045091	regulation of single stranded viral RNA replication via double stranded DNA intermediate(GO:0045091)
0.0	0.0	GO:0002230	positive regulation of defense response to virus by host(GO:0002230)
0.0	0.0	GO:0010642	negative regulation of platelet-derived growth factor receptor signaling pathway(GO:0010642)
0.0	0.1	GO:0070670	response to interleukin-4(GO:0070670)
0.0	0.1	GO:0007100	mitotic centrosome separation(GO:0007100)
0.0	0.0	GO:0010954	positive regulation of protein processing(GO:0010954) positive regulation of protein maturation(GO:1903319)
0.0	0.2	GO:0000085	mitotic G2 phase(GO:0000085) G2 phase(GO:0051319)
0.0	0.1	GO:0060023	soft palate development(GO:0060023)
0.0	0.2	GO:0030225	macrophage differentiation(GO:0030225)
0.0	0.3	GO:0042255	ribosome assembly(GO:0042255)
0.0	0.1	GO:0014051	gamma-aminobutyric acid secretion(GO:0014051)
0.0	0.0	GO:0042348	regulation of NF-kappaB import into nucleus(GO:0042345) NF-kappaB import into nucleus(GO:0042348)
0.0	0.2	GO:0042994	cytoplasmic sequestering of transcription factor(GO:0042994)
0.0	0.3	GO:0019724	B cell mediated immunity(GO:0019724)
0.0	0.1	GO:0046784	viral mRNA export from host cell nucleus(GO:0046784)
0.0	0.0	GO:0034447	very-low-density lipoprotein particle clearance(GO:0034447)
0.0	0.2	GO:0006895	Golgi to endosome transport(GO:0006895) Golgi to vacuole transport(GO:0006896)
0.0	0.1	GO:0030186	melatonin metabolic process(GO:0030186) melatonin biosynthetic process(GO:0030187)
0.0	0.1	GO:0010792	DNA double-strand break processing involved in repair via single-strand annealing(GO:0010792) double-strand break repair via single-strand annealing(GO:0045002)
0.0	0.1	GO:0034372	triglyceride-rich lipoprotein particle remodeling(GO:0034370) very-low-density lipoprotein particle remodeling(GO:0034372)
0.0	0.1	GO:0060760	positive regulation of response to cytokine stimulus(GO:0060760)
0.0	0.1	GO:1900087	traversing start control point of mitotic cell cycle(GO:0007089) positive regulation of G1/S transition of mitotic cell cycle(GO:1900087) positive regulation of cell cycle G1/S phase transition(GO:1902808)
0.0	0.2	GO:0090630	activation of GTPase activity(GO:0090630)
0.0	0.0	GO:0014874	response to stimulus involved in regulation of muscle adaptation(GO:0014874)
0.0	0.1	GO:0001945	lymph vessel development(GO:0001945)
0.0	0.3	GO:0016601	Rac protein signal transduction(GO:0016601)
0.0	0.1	GO:0000089	mitotic metaphase(GO:0000089)
0.0	0.1	GO:0000012	single strand break repair(GO:0000012)
0.0	0.1	GO:0006264	mitochondrial DNA replication(GO:0006264)
0.0	0.1	GO:0032525	somite rostral/caudal axis specification(GO:0032525)
0.0	0.1	GO:0035335	peptidyl-tyrosine dephosphorylation(GO:0035335)
0.0	0.1	GO:0000103	sulfate assimilation(GO:0000103)
0.0	0.3	GO:0019933	cAMP-mediated signaling(GO:0019933)
0.0	0.1	GO:0031115	negative regulation of microtubule polymerization(GO:0031115)
0.0	0.5	GO:0050772	positive regulation of axonogenesis(GO:0050772)
0.0	0.2	GO:0051353	positive regulation of oxidoreductase activity(GO:0051353)
0.0	0.2	GO:0015693	magnesium ion transport(GO:0015693)
0.0	0.0	GO:0032494	response to peptidoglycan(GO:0032494)
0.0	0.2	GO:0007032	endosome organization(GO:0007032)
0.0	0.1	GO:0010739	positive regulation of protein kinase A signaling(GO:0010739)
0.0	0.1	GO:0006546	glycine catabolic process(GO:0006546)
0.0	0.1	GO:0015074	DNA integration(GO:0015074)
0.0	0.1	GO:0042816	pyridoxine metabolic process(GO:0008614) pyridoxine biosynthetic process(GO:0008615) vitamin B6 metabolic process(GO:0042816) vitamin B6 biosynthetic process(GO:0042819)
0.0	0.2	GO:0007379	segment specification(GO:0007379)
0.0	0.0	GO:0042226	interleukin-6 biosynthetic process(GO:0042226)
0.0	0.0	GO:0048539	bone marrow development(GO:0048539)
0.0	0.1	GO:0050691	regulation of defense response to virus by host(GO:0050691)
0.0	0.0	GO:0033504	floor plate development(GO:0033504)
0.0	0.1	GO:0072583	synaptic vesicle recycling(GO:0036465) synaptic vesicle endocytosis(GO:0048488) clathrin-mediated endocytosis(GO:0072583)
0.0	0.0	GO:0040001	establishment of mitotic spindle localization(GO:0040001)
0.0	0.0	GO:0045347	negative regulation of MHC class II biosynthetic process(GO:0045347)
0.0	0.0	GO:0045603	positive regulation of endothelial cell differentiation(GO:0045603)
0.0	0.0	GO:0042130	negative regulation of T cell proliferation(GO:0042130)
0.0	0.1	GO:0006020	inositol metabolic process(GO:0006020)
0.0	0.1	GO:0007090	obsolete regulation of S phase of mitotic cell cycle(GO:0007090)
0.0	0.0	GO:0045618	positive regulation of keratinocyte differentiation(GO:0045618)
0.0	0.0	GO:0075733	multi-organism transport(GO:0044766) transport of virus(GO:0046794) intracellular transport of virus(GO:0075733) multi-organism localization(GO:1902579) multi-organism intracellular transport(GO:1902583)
0.0	0.0	GO:2000114	regulation of establishment of cell polarity(GO:2000114)
0.0	0.1	GO:0050775	positive regulation of dendrite morphogenesis(GO:0050775) positive regulation of dendrite development(GO:1900006)
0.0	0.0	GO:0046968	peptide antigen transport(GO:0046968)
0.0	0.0	GO:0043983	histone H4-K12 acetylation(GO:0043983)
0.0	0.0	GO:0002085	inhibition of neuroepithelial cell differentiation(GO:0002085)
0.0	0.1	GO:0050910	detection of mechanical stimulus involved in sensory perception of sound(GO:0050910)
0.0	0.1	GO:0031427	response to methotrexate(GO:0031427)
0.0	0.0	GO:0031646	positive regulation of neurological system process(GO:0031646)
0.0	0.1	GO:0006570	tyrosine metabolic process(GO:0006570)
0.0	0.1	GO:0001573	ganglioside metabolic process(GO:0001573)
0.0	0.0	GO:0016572	histone phosphorylation(GO:0016572)
0.0	0.2	GO:0006379	mRNA cleavage(GO:0006379)
0.0	0.1	GO:0046697	decidualization(GO:0046697)
0.0	0.0	GO:0043457	regulation of cellular respiration(GO:0043457)
0.0	0.0	GO:0018125	peptidyl-cysteine methylation(GO:0018125)
0.0	0.1	GO:0046689	response to mercury ion(GO:0046689)
0.0	0.0	GO:0045084	positive regulation of interleukin-12 biosynthetic process(GO:0045084)
0.0	0.0	GO:0060676	ureteric bud formation(GO:0060676)
0.0	0.0	GO:0000462	endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000447) maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000462) cleavage involved in rRNA processing(GO:0000469) endonucleolytic cleavage involved in rRNA processing(GO:0000478) endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000479) maturation of SSU-rRNA(GO:0030490) RNA phosphodiester bond hydrolysis, endonucleolytic(GO:0090502)
0.0	0.1	GO:0040020	regulation of meiotic nuclear division(GO:0040020)
0.0	0.1	GO:0045351	type I interferon biosynthetic process(GO:0045351)
0.0	0.1	GO:0009804	phenylpropanoid metabolic process(GO:0009698) coumarin metabolic process(GO:0009804)
0.0	0.0	GO:0019605	butyrate metabolic process(GO:0019605)
0.0	0.1	GO:0007191	adenylate cyclase-activating dopamine receptor signaling pathway(GO:0007191)
0.0	0.0	GO:0010457	centriole-centriole cohesion(GO:0010457)
0.0	0.0	GO:0003077	obsolete negative regulation of diuresis(GO:0003077)
0.0	0.4	GO:0060333	interferon-gamma-mediated signaling pathway(GO:0060333)
0.0	0.4	GO:0003333	amino acid transmembrane transport(GO:0003333)
0.0	0.1	GO:0042359	vitamin D metabolic process(GO:0042359)
0.0	0.0	GO:0033632	regulation of cell-cell adhesion mediated by integrin(GO:0033632)
0.0	1.0	GO:0000216	obsolete M/G1 transition of mitotic cell cycle(GO:0000216)
0.0	0.1	GO:0009649	entrainment of circadian clock(GO:0009649)
0.0	0.4	GO:0021549	cerebellum development(GO:0021549)
0.0	0.1	GO:0006516	glycoprotein catabolic process(GO:0006516)
0.0	0.1	GO:0000076	DNA replication checkpoint(GO:0000076)
0.0	0.1	GO:0000038	very long-chain fatty acid metabolic process(GO:0000038)
0.0	0.2	GO:0016578	histone deubiquitination(GO:0016578)
0.0	0.0	GO:0035511	oxidative DNA demethylation(GO:0035511)
0.0	0.0	GO:0071549	cellular response to dexamethasone stimulus(GO:0071549)
0.0	0.0	GO:0060596	mammary placode formation(GO:0060596)
0.0	0.0	GO:0006011	UDP-glucose metabolic process(GO:0006011)
0.0	0.4	GO:0016579	protein deubiquitination(GO:0016579)
0.0	0.1	GO:0045746	negative regulation of Notch signaling pathway(GO:0045746)
0.0	0.1	GO:0016098	monoterpenoid metabolic process(GO:0016098)
0.0	0.0	GO:0030174	regulation of DNA-dependent DNA replication initiation(GO:0030174)
0.0	0.1	GO:0032008	positive regulation of TOR signaling(GO:0032008)
0.0	0.1	GO:0034341	response to interferon-gamma(GO:0034341)
0.0	0.0	GO:0044818	mitotic G2 DNA damage checkpoint(GO:0007095) mitotic G2/M transition checkpoint(GO:0044818)
0.0	0.3	GO:0000289	nuclear-transcribed mRNA poly(A) tail shortening(GO:0000289)
0.0	0.2	GO:0016254	preassembly of GPI anchor in ER membrane(GO:0016254)
0.0	0.0	GO:0072393	microtubule anchoring at microtubule organizing center(GO:0072393)
0.0	0.2	GO:0043967	histone H4 acetylation(GO:0043967)
0.0	0.1	GO:0009051	pentose-phosphate shunt, oxidative branch(GO:0009051)
0.0	0.0	GO:0045988	negative regulation of striated muscle contraction(GO:0045988)
0.0	0.1	GO:0045109	intermediate filament organization(GO:0045109)
0.0	0.0	GO:0009301	snRNA transcription(GO:0009301)
0.0	0.1	GO:0033523	histone H2B ubiquitination(GO:0033523)
0.0	0.0	GO:0046688	response to copper ion(GO:0046688)
0.0	0.1	GO:0046415	urate metabolic process(GO:0046415)
0.0	0.6	GO:0007498	mesoderm development(GO:0007498)
0.0	0.1	GO:0045987	positive regulation of smooth muscle contraction(GO:0045987)
0.0	0.1	GO:0050962	detection of light stimulus involved in visual perception(GO:0050908) detection of light stimulus involved in sensory perception(GO:0050962)
0.0	0.1	GO:0010669	epithelial structure maintenance(GO:0010669) maintenance of gastrointestinal epithelium(GO:0030277)
0.0	0.0	GO:0060586	multicellular organismal iron ion homeostasis(GO:0060586)
0.0	0.0	GO:0060766	negative regulation of androgen receptor signaling pathway(GO:0060766)
0.0	0.0	GO:0042772	DNA damage response, signal transduction resulting in transcription(GO:0042772)
0.0	0.0	GO:0032878	regulation of establishment or maintenance of cell polarity(GO:0032878)
0.0	0.0	GO:0060157	urinary bladder development(GO:0060157)
0.0	0.1	GO:0043628	ncRNA 3'-end processing(GO:0043628)
0.0	0.0	GO:0016576	histone dephosphorylation(GO:0016576)
0.0	0.0	GO:0032042	mitochondrial DNA metabolic process(GO:0032042)
0.0	0.1	GO:0000183	chromatin silencing at rDNA(GO:0000183)
0.0	0.2	GO:0080171	lysosome organization(GO:0007040) lytic vacuole organization(GO:0080171)
0.0	0.0	GO:0034145	regulation of toll-like receptor 4 signaling pathway(GO:0034143) positive regulation of toll-like receptor 4 signaling pathway(GO:0034145)
0.0	0.0	GO:1903726	negative regulation of phospholipid metabolic process(GO:1903726)
0.0	0.0	GO:0019388	galactose catabolic process(GO:0019388)
0.0	0.1	GO:0032000	positive regulation of fatty acid beta-oxidation(GO:0032000)
0.0	0.2	GO:0042776	mitochondrial ATP synthesis coupled proton transport(GO:0042776)
0.0	0.0	GO:0010832	negative regulation of myotube differentiation(GO:0010832)
0.0	0.0	GO:0048570	notochord morphogenesis(GO:0048570)
0.0	0.0	GO:0015851	nucleobase transport(GO:0015851)
0.0	0.0	GO:0010107	potassium ion import(GO:0010107)
0.0	0.1	GO:0042219	cellular modified amino acid catabolic process(GO:0042219)
0.0	0.1	GO:0008635	activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c(GO:0008635)
0.0	0.0	GO:0051103	DNA ligation involved in DNA repair(GO:0051103)
0.0	0.0	GO:0000019	regulation of mitotic recombination(GO:0000019)
0.0	0.0	GO:0010737	protein kinase A signaling(GO:0010737) regulation of protein kinase A signaling(GO:0010738)
0.0	0.0	GO:0000380	alternative mRNA splicing, via spliceosome(GO:0000380)
0.0	0.1	GO:0043252	sodium-independent organic anion transport(GO:0043252)
0.0	0.0	GO:0021542	dentate gyrus development(GO:0021542)
0.0	0.2	GO:0033209	tumor necrosis factor-mediated signaling pathway(GO:0033209)
0.0	0.1	GO:0015813	L-glutamate transport(GO:0015813)
0.0	0.0	GO:0032604	granulocyte macrophage colony-stimulating factor production(GO:0032604) regulation of granulocyte macrophage colony-stimulating factor production(GO:0032645)
0.0	0.0	GO:0034121	regulation of toll-like receptor signaling pathway(GO:0034121)
0.0	0.2	GO:0030968	endoplasmic reticulum unfolded protein response(GO:0030968) cellular response to unfolded protein(GO:0034620)
0.0	0.1	GO:0009129	pyrimidine nucleoside monophosphate metabolic process(GO:0009129)
0.0	0.0	GO:0006391	transcription initiation from mitochondrial promoter(GO:0006391)
0.0	0.1	GO:0032755	positive regulation of interleukin-6 production(GO:0032755)
0.0	0.2	GO:0051351	positive regulation of ligase activity(GO:0051351)
0.0	0.1	GO:0003009	skeletal muscle contraction(GO:0003009)
0.0	0.1	GO:0006072	glycerol-3-phosphate metabolic process(GO:0006072)
0.0	0.0	GO:0070265	necrotic cell death(GO:0070265)
0.0	0.2	GO:0001938	positive regulation of endothelial cell proliferation(GO:0001938)
0.0	0.1	GO:0034314	Arp2/3 complex-mediated actin nucleation(GO:0034314)
0.0	0.0	GO:0006824	cobalt ion transport(GO:0006824)
0.0	0.0	GO:0045943	positive regulation of transcription from RNA polymerase I promoter(GO:0045943)
0.0	0.3	GO:0006635	fatty acid beta-oxidation(GO:0006635)
0.0	0.0	GO:0016557	peroxisome membrane biogenesis(GO:0016557)
0.0	0.0	GO:2000831	corticosteroid hormone secretion(GO:0035930) regulation of steroid hormone secretion(GO:2000831) regulation of corticosteroid hormone secretion(GO:2000846)
0.0	0.1	GO:0034033	nucleoside bisphosphate biosynthetic process(GO:0033866) ribonucleoside bisphosphate biosynthetic process(GO:0034030) purine nucleoside bisphosphate biosynthetic process(GO:0034033)
0.0	0.0	GO:0043653	mitochondrial fragmentation involved in apoptotic process(GO:0043653)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.3	GO:0042105	alpha-beta T cell receptor complex(GO:0042105)
0.1	0.3	GO:0000942	condensed nuclear chromosome outer kinetochore(GO:0000942)
0.1	0.2	GO:0072487	MSL complex(GO:0072487)
0.1	0.2	GO:0070022	transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.1	0.4	GO:0045179	apical cortex(GO:0045179)
0.1	0.5	GO:0042589	zymogen granule membrane(GO:0042589)
0.1	0.4	GO:0044224	juxtaparanode region of axon(GO:0044224)
0.1	0.1	GO:0031931	TORC1 complex(GO:0031931)
0.1	0.5	GO:0042598	obsolete vesicular fraction(GO:0042598)
0.1	0.2	GO:0045323	interleukin-1 receptor complex(GO:0045323)
0.1	0.3	GO:0005797	Golgi medial cisterna(GO:0005797)
0.1	0.8	GO:0005942	phosphatidylinositol 3-kinase complex(GO:0005942)
0.1	0.4	GO:0001891	phagocytic cup(GO:0001891)
0.1	0.5	GO:0001772	immunological synapse(GO:0001772)
0.1	0.5	GO:0034518	mRNA cap binding complex(GO:0005845) RNA cap binding complex(GO:0034518)
0.1	0.2	GO:0044462	external encapsulating structure part(GO:0044462)
0.1	0.2	GO:0042583	chromaffin granule(GO:0042583) chromaffin granule membrane(GO:0042584)
0.0	0.2	GO:0033256	I-kappaB/NF-kappaB complex(GO:0033256)
0.0	0.2	GO:0070695	FHF complex(GO:0070695)
0.0	0.4	GO:0000808	origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.0	0.4	GO:0045239	tricarboxylic acid cycle enzyme complex(GO:0045239)
0.0	0.3	GO:0070688	MLL5-L complex(GO:0070688)
0.0	0.1	GO:0001940	male pronucleus(GO:0001940)
0.0	0.3	GO:0043190	ATP-binding cassette (ABC) transporter complex(GO:0043190)
0.0	0.3	GO:0016461	unconventional myosin complex(GO:0016461)
0.0	0.1	GO:0005896	interleukin-6 receptor complex(GO:0005896)
0.0	0.2	GO:0019907	cyclin-dependent protein kinase activating kinase holoenzyme complex(GO:0019907)
0.0	0.2	GO:0005639	integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229) nuclear membrane part(GO:0044453)
0.0	0.3	GO:0042101	T cell receptor complex(GO:0042101)
0.0	0.4	GO:0008180	COP9 signalosome(GO:0008180)
0.0	0.1	GO:0000137	Golgi cis cisterna(GO:0000137)
0.0	0.1	GO:0009331	glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.0	0.2	GO:0031254	uropod(GO:0001931) cell trailing edge(GO:0031254)
0.0	0.2	GO:0031264	death-inducing signaling complex(GO:0031264)
0.0	0.4	GO:0010494	cytoplasmic stress granule(GO:0010494)
0.0	0.1	GO:0032045	guanyl-nucleotide exchange factor complex(GO:0032045)
0.0	0.1	GO:0071438	invadopodium membrane(GO:0071438)
0.0	0.4	GO:0031672	A band(GO:0031672)
0.0	0.2	GO:0014731	spectrin-associated cytoskeleton(GO:0014731)
0.0	0.2	GO:0042582	primary lysosome(GO:0005766) azurophil granule(GO:0042582)
0.0	0.2	GO:0048786	presynaptic active zone(GO:0048786)
0.0	0.2	GO:0034451	centriolar satellite(GO:0034451)
0.0	0.1	GO:0043218	compact myelin(GO:0043218)
0.0	0.1	GO:0033150	cytoskeletal calyx(GO:0033150)
0.0	0.1	GO:0030934	anchoring collagen complex(GO:0030934)
0.0	0.3	GO:0043209	myelin sheath(GO:0043209)
0.0	0.4	GO:0016514	SWI/SNF complex(GO:0016514)
0.0	0.3	GO:0008250	oligosaccharyltransferase complex(GO:0008250)
0.0	0.3	GO:0005838	proteasome regulatory particle(GO:0005838)
0.0	0.2	GO:0043020	NADPH oxidase complex(GO:0043020)
0.0	0.3	GO:0034362	low-density lipoprotein particle(GO:0034362)
0.0	0.3	GO:0031519	PcG protein complex(GO:0031519)
0.0	0.0	GO:0031235	intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.0	0.2	GO:0030893	meiotic cohesin complex(GO:0030893)
0.0	0.2	GO:0098984	asymmetric synapse(GO:0032279) neuron to neuron synapse(GO:0098984)
0.0	0.1	GO:0001652	granular component(GO:0001652)
0.0	0.3	GO:0046658	anchored component of plasma membrane(GO:0046658)
0.0	0.1	GO:0044298	neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.0	0.5	GO:0000932	cytoplasmic mRNA processing body(GO:0000932)
0.0	0.1	GO:0005862	muscle thin filament tropomyosin(GO:0005862)
0.0	1.0	GO:0035097	methyltransferase complex(GO:0034708) histone methyltransferase complex(GO:0035097)
0.0	1.0	GO:0030173	integral component of Golgi membrane(GO:0030173)
0.0	0.1	GO:0031616	spindle pole centrosome(GO:0031616)
0.0	0.3	GO:0071203	WASH complex(GO:0071203)
0.0	0.1	GO:0031095	platelet dense tubular network membrane(GO:0031095)
0.0	0.1	GO:0000300	obsolete peripheral to membrane of membrane fraction(GO:0000300)
0.0	0.0	GO:0000800	lateral element(GO:0000800)
0.0	0.3	GO:0016235	aggresome(GO:0016235)
0.0	0.2	GO:0032040	small-subunit processome(GO:0032040)
0.0	0.1	GO:0000444	MIS12/MIND type complex(GO:0000444)
0.0	0.4	GO:0005763	organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.0	0.1	GO:0033553	rDNA heterochromatin(GO:0033553)
0.0	0.2	GO:0033162	melanosome membrane(GO:0033162) chitosome(GO:0045009)
0.0	0.2	GO:0005775	vacuolar lumen(GO:0005775)
0.0	1.0	GO:0016605	PML body(GO:0016605)
0.0	0.1	GO:0005850	eukaryotic translation initiation factor 2 complex(GO:0005850)
0.0	0.1	GO:0001741	XY body(GO:0001741)
0.0	0.1	GO:0030670	phagocytic vesicle membrane(GO:0030670)
0.0	0.1	GO:0042788	polysomal ribosome(GO:0042788)
0.0	0.1	GO:0032839	dendrite cytoplasm(GO:0032839)
0.0	0.1	GO:0030895	apolipoprotein B mRNA editing enzyme complex(GO:0030895)
0.0	0.1	GO:0030673	axolemma(GO:0030673)
0.0	0.1	GO:0030904	retromer complex(GO:0030904)
0.0	0.2	GO:0005844	polysome(GO:0005844)
0.0	0.1	GO:0000346	transcription export complex(GO:0000346)
0.0	0.1	GO:0005742	mitochondrial outer membrane translocase complex(GO:0005742)
0.0	0.0	GO:0032777	Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.0	0.2	GO:0090568	NuRD complex(GO:0016581) CHD-type complex(GO:0090545) nuclear transcriptional repressor complex(GO:0090568)
0.0	2.1	GO:0009897	external side of plasma membrane(GO:0009897)
0.0	0.0	GO:0032009	early phagosome(GO:0032009)
0.0	0.3	GO:0030864	cortical actin cytoskeleton(GO:0030864)
0.0	0.1	GO:0005869	dynactin complex(GO:0005869)
0.0	0.0	GO:0071256	Sec61 translocon complex(GO:0005784) translocon complex(GO:0071256)
0.0	0.2	GO:0005669	transcription factor TFIID complex(GO:0005669)
0.0	0.0	GO:0034363	intermediate-density lipoprotein particle(GO:0034363)
0.0	0.0	GO:0070820	tertiary granule(GO:0070820)
0.0	0.2	GO:0005720	nuclear heterochromatin(GO:0005720)
0.0	0.1	GO:0070552	BRISC complex(GO:0070552)
0.0	0.1	GO:0032590	dendrite membrane(GO:0032590)
0.0	0.0	GO:0070062	extracellular exosome(GO:0070062) extracellular vesicle(GO:1903561)
0.0	0.0	GO:0033011	perinuclear theca(GO:0033011)
0.0	0.0	GO:0010369	chromocenter(GO:0010369)
0.0	0.2	GO:0030130	clathrin coat of trans-Golgi network vesicle(GO:0030130)
0.0	0.0	GO:0008282	ATP-sensitive potassium channel complex(GO:0008282)
0.0	0.1	GO:0048500	signal recognition particle, endoplasmic reticulum targeting(GO:0005786) signal recognition particle(GO:0048500)
0.0	0.1	GO:0042627	chylomicron(GO:0042627)
0.0	0.8	GO:0000502	proteasome complex(GO:0000502)
0.0	0.1	GO:0005678	obsolete chromatin assembly complex(GO:0005678)
0.0	0.1	GO:0042555	MCM complex(GO:0042555)
0.0	1.7	GO:0005769	early endosome(GO:0005769)
0.0	0.1	GO:0005683	U7 snRNP(GO:0005683)
0.0	0.3	GO:0005680	anaphase-promoting complex(GO:0005680)
0.0	0.1	GO:0031307	integral component of mitochondrial outer membrane(GO:0031307)
0.0	0.0	GO:0000164	protein phosphatase type 1 complex(GO:0000164)
0.0	0.0	GO:0030688	preribosome, small subunit precursor(GO:0030688)
0.0	0.1	GO:0016272	prefoldin complex(GO:0016272)
0.0	0.2	GO:1990777	protein-lipid complex(GO:0032994) plasma lipoprotein particle(GO:0034358) lipoprotein particle(GO:1990777)
0.0	0.1	GO:0001518	voltage-gated sodium channel complex(GO:0001518)
0.0	0.0	GO:0005954	calcium- and calmodulin-dependent protein kinase complex(GO:0005954)
0.0	0.0	GO:0031465	Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
0.0	0.1	GO:0031231	integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231)
0.0	0.0	GO:0002080	acrosomal membrane(GO:0002080)
0.0	0.1	GO:0035631	CD40 receptor complex(GO:0035631)
0.0	0.1	GO:0005861	troponin complex(GO:0005861)
0.0	0.1	GO:0016234	inclusion body(GO:0016234)
0.0	0.1	GO:0030127	COPII vesicle coat(GO:0030127)
0.0	0.1	GO:0000153	cytoplasmic ubiquitin ligase complex(GO:0000153)
0.0	0.0	GO:0042825	TAP complex(GO:0042825)
0.0	0.4	GO:0005876	spindle microtubule(GO:0005876)
0.0	0.0	GO:0017071	intracellular cyclic nucleotide activated cation channel complex(GO:0017071)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	0.6	GO:0004911	interleukin-2 receptor activity(GO:0004911)
0.2	0.5	GO:0004517	nitric-oxide synthase activity(GO:0004517)
0.1	0.4	GO:0046935	1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.1	0.4	GO:0016309	1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
0.1	1.9	GO:0004697	protein kinase C activity(GO:0004697)
0.1	1.3	GO:0016493	C-C chemokine receptor activity(GO:0016493)
0.1	0.6	GO:0046934	phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) phosphatidylinositol bisphosphate kinase activity(GO:0052813)
0.1	0.9	GO:0015271	outward rectifier potassium channel activity(GO:0015271)
0.1	0.6	GO:0004563	beta-N-acetylhexosaminidase activity(GO:0004563)
0.1	0.4	GO:0004528	phosphodiesterase I activity(GO:0004528)
0.1	0.5	GO:0030955	potassium ion binding(GO:0030955)
0.1	0.3	GO:0003726	double-stranded RNA adenosine deaminase activity(GO:0003726)
0.1	0.6	GO:0016494	C-X-C chemokine receptor activity(GO:0016494)
0.1	0.1	GO:0001098	basal transcription machinery binding(GO:0001098) basal RNA polymerase II transcription machinery binding(GO:0001099)
0.1	1.0	GO:0016888	endodeoxyribonuclease activity, producing 5'-phosphomonoesters(GO:0016888)
0.1	0.2	GO:0047756	chondroitin 4-sulfotransferase activity(GO:0047756)
0.1	0.3	GO:0004583	dolichyl-phosphate-glucose-glycolipid alpha-glucosyltransferase activity(GO:0004583)
0.1	0.1	GO:0019959	C-X-C chemokine binding(GO:0019958) interleukin-8 binding(GO:0019959)
0.1	0.2	GO:0008545	JUN kinase kinase activity(GO:0008545)
0.1	0.2	GO:0004465	lipoprotein lipase activity(GO:0004465)
0.1	0.2	GO:0016842	amidine-lyase activity(GO:0016842)
0.1	0.2	GO:0004476	mannose-6-phosphate isomerase activity(GO:0004476)
0.1	0.5	GO:0003688	DNA replication origin binding(GO:0003688)
0.1	0.5	GO:0004955	prostaglandin receptor activity(GO:0004955)
0.1	0.3	GO:0030284	estrogen receptor activity(GO:0030284)
0.1	0.5	GO:0050700	CARD domain binding(GO:0050700)
0.1	0.7	GO:0004859	phospholipase inhibitor activity(GO:0004859)
0.1	0.2	GO:0046923	ER retention sequence binding(GO:0046923)
0.1	0.2	GO:0030368	interleukin-17 receptor activity(GO:0030368)
0.1	0.1	GO:0070215	obsolete MDM2 binding(GO:0070215)
0.1	0.3	GO:0005131	growth hormone receptor binding(GO:0005131)
0.1	0.2	GO:0015562	efflux transmembrane transporter activity(GO:0015562)
0.1	0.2	GO:0033691	sialic acid binding(GO:0033691)
0.1	0.8	GO:0005095	GTPase inhibitor activity(GO:0005095)
0.1	0.2	GO:0030899	calcium-dependent ATPase activity(GO:0030899)
0.1	0.3	GO:0016907	G-protein coupled acetylcholine receptor activity(GO:0016907)
0.1	0.3	GO:0004904	interferon receptor activity(GO:0004904)
0.1	0.2	GO:0015925	galactosidase activity(GO:0015925)
0.1	0.2	GO:0004083	bisphosphoglycerate mutase activity(GO:0004082) bisphosphoglycerate 2-phosphatase activity(GO:0004083) phosphoglycerate mutase activity(GO:0004619)
0.1	0.5	GO:0046527	glucosyltransferase activity(GO:0046527)
0.1	0.2	GO:0001758	retinal dehydrogenase activity(GO:0001758)
0.1	0.2	GO:0015379	potassium:chloride symporter activity(GO:0015379)
0.1	1.3	GO:0001608	G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.1	1.9	GO:0004715	non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.1	0.1	GO:0010314	phosphatidylinositol-5-phosphate binding(GO:0010314)
0.1	0.3	GO:0061133	endopeptidase activator activity(GO:0061133)
0.1	0.3	GO:0016308	1-phosphatidylinositol-4-phosphate 5-kinase activity(GO:0016308)
0.1	0.3	GO:0005381	iron ion transmembrane transporter activity(GO:0005381)
0.1	0.2	GO:0016509	long-chain-3-hydroxyacyl-CoA dehydrogenase activity(GO:0016509)
0.1	0.2	GO:0004719	protein-L-isoaspartate (D-aspartate) O-methyltransferase activity(GO:0004719)
0.1	0.5	GO:0048531	beta-1,3-galactosyltransferase activity(GO:0048531)
0.1	0.1	GO:0016312	inositol bisphosphate phosphatase activity(GO:0016312)
0.1	0.2	GO:0004607	phosphatidylcholine-sterol O-acyltransferase activity(GO:0004607)
0.1	0.1	GO:0010340	carboxyl-O-methyltransferase activity(GO:0010340) protein carboxyl O-methyltransferase activity(GO:0051998)
0.0	0.1	GO:0030375	thyroid hormone receptor coactivator activity(GO:0030375)
0.0	0.3	GO:0070087	chromo shadow domain binding(GO:0070087)
0.0	0.2	GO:0047238	glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity(GO:0047238)
0.0	0.1	GO:0043141	ATP-dependent 5'-3' DNA helicase activity(GO:0043141)
0.0	0.1	GO:0042608	T cell receptor binding(GO:0042608)
0.0	0.1	GO:0016728	ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
0.0	0.1	GO:0003836	beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.0	0.2	GO:0004974	leukotriene receptor activity(GO:0004974)
0.0	0.2	GO:0008266	poly(U) RNA binding(GO:0008266)
0.0	0.1	GO:0008474	palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.0	0.5	GO:0008239	dipeptidyl-peptidase activity(GO:0008239)
0.0	0.1	GO:0042392	sphingosine-1-phosphate phosphatase activity(GO:0042392)
0.0	0.3	GO:0070577	lysine-acetylated histone binding(GO:0070577)
0.0	0.1	GO:0008454	alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.0	2.1	GO:0005070	SH3/SH2 adaptor activity(GO:0005070)
0.0	0.1	GO:0004966	galanin receptor activity(GO:0004966)
0.0	1.0	GO:0004177	aminopeptidase activity(GO:0004177)
0.0	0.1	GO:0052658	inositol-1,4,5-trisphosphate 5-phosphatase activity(GO:0052658) inositol-1,3,4,5-tetrakisphosphate 5-phosphatase activity(GO:0052659)
0.0	0.2	GO:0019911	structural constituent of myelin sheath(GO:0019911)
0.0	0.1	GO:0003910	DNA ligase activity(GO:0003909) DNA ligase (ATP) activity(GO:0003910)
0.0	0.3	GO:0004568	chitinase activity(GO:0004568)
0.0	0.1	GO:0031628	opioid receptor binding(GO:0031628)
0.0	0.1	GO:0004886	9-cis retinoic acid receptor activity(GO:0004886)
0.0	0.2	GO:0034452	dynactin binding(GO:0034452)
0.0	0.6	GO:0008373	sialyltransferase activity(GO:0008373)
0.0	0.1	GO:0005049	nuclear export signal receptor activity(GO:0005049)
0.0	0.2	GO:0070513	death domain binding(GO:0070513)
0.0	0.1	GO:0055103	ligase regulator activity(GO:0055103) ubiquitin-protein transferase regulator activity(GO:0055106)
0.0	0.1	GO:0000739	obsolete DNA strand annealing activity(GO:0000739)
0.0	0.3	GO:0005114	type II transforming growth factor beta receptor binding(GO:0005114)
0.0	0.1	GO:0004873	asialoglycoprotein receptor activity(GO:0004873)
0.0	0.0	GO:0035197	siRNA binding(GO:0035197)
0.0	0.1	GO:0004367	glycerol-3-phosphate dehydrogenase [NAD+] activity(GO:0004367)
0.0	0.4	GO:0031078	histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041) histone deacetylase activity (H4-K16 specific)(GO:0034739) NAD-dependent histone deacetylase activity (H4-K16 specific)(GO:0046970)
0.0	0.1	GO:0008131	primary amine oxidase activity(GO:0008131)
0.0	0.1	GO:0019788	NEDD8 transferase activity(GO:0019788)
0.0	0.1	GO:0035252	UDP-xylosyltransferase activity(GO:0035252) xylosyltransferase activity(GO:0042285)
0.0	0.1	GO:0031685	adenosine receptor binding(GO:0031685)
0.0	0.6	GO:0005086	ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0	0.2	GO:0000339	RNA cap binding(GO:0000339)
0.0	0.1	GO:0004949	cannabinoid receptor activity(GO:0004949)
0.0	0.2	GO:0016502	purinergic nucleotide receptor activity(GO:0001614) nucleotide receptor activity(GO:0016502)
0.0	0.5	GO:0043027	cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.0	0.4	GO:0004016	adenylate cyclase activity(GO:0004016)
0.0	0.1	GO:0005220	inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.0	0.1	GO:0004045	aminoacyl-tRNA hydrolase activity(GO:0004045)
0.0	0.1	GO:0008401	retinoic acid 4-hydroxylase activity(GO:0008401)
0.0	0.2	GO:0001784	phosphotyrosine binding(GO:0001784)
0.0	0.1	GO:0031957	very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.0	0.9	GO:0003950	NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.0	0.2	GO:0043325	phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.0	0.1	GO:0043024	ribosomal small subunit binding(GO:0043024)
0.0	0.1	GO:0042799	histone methyltransferase activity (H4-K20 specific)(GO:0042799)
0.0	0.1	GO:0030346	protein phosphatase 2B binding(GO:0030346)
0.0	0.2	GO:0016841	ammonia-lyase activity(GO:0016841)
0.0	0.1	GO:0045159	myosin II binding(GO:0045159)
0.0	0.2	GO:0004704	NF-kappaB-inducing kinase activity(GO:0004704)
0.0	0.1	GO:0004449	isocitrate dehydrogenase (NAD+) activity(GO:0004449)
0.0	0.6	GO:0043621	protein self-association(GO:0043621)
0.0	0.3	GO:0004579	oligosaccharyl transferase activity(GO:0004576) dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.0	0.1	GO:0071723	lipopeptide binding(GO:0071723)
0.0	0.1	GO:0004815	aspartate-tRNA ligase activity(GO:0004815)
0.0	0.2	GO:0004983	neuropeptide Y receptor activity(GO:0004983)
0.0	0.2	GO:0016520	growth hormone-releasing hormone receptor activity(GO:0016520)
0.0	0.1	GO:0033300	dehydroascorbic acid transporter activity(GO:0033300)
0.0	0.1	GO:0003873	6-phosphofructo-2-kinase activity(GO:0003873)
0.0	0.1	GO:0030292	protein tyrosine kinase inhibitor activity(GO:0030292)
0.0	0.1	GO:0008440	inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440) inositol trisphosphate kinase activity(GO:0051766)
0.0	0.2	GO:0050786	RAGE receptor binding(GO:0050786)
0.0	0.2	GO:0004691	cAMP-dependent protein kinase activity(GO:0004691)
0.0	0.1	GO:0008745	N-acetylmuramoyl-L-alanine amidase activity(GO:0008745)
0.0	0.1	GO:0044020	histone methyltransferase activity (H4-R3 specific)(GO:0044020)
0.0	0.2	GO:0004703	G-protein coupled receptor kinase activity(GO:0004703)
0.0	0.1	GO:0032296	ribonuclease III activity(GO:0004525) double-stranded RNA-specific ribonuclease activity(GO:0032296)
0.0	0.3	GO:0051018	protein kinase A binding(GO:0051018)
0.0	0.1	GO:0032137	guanine/thymine mispair binding(GO:0032137)
0.0	0.4	GO:0017017	MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.0	0.1	GO:0008568	microtubule-severing ATPase activity(GO:0008568)
0.0	0.1	GO:0018685	alkane 1-monooxygenase activity(GO:0018685)
0.0	0.1	GO:0004950	G-protein coupled chemoattractant receptor activity(GO:0001637) chemokine receptor activity(GO:0004950)
0.0	0.1	GO:0005068	transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.0	0.2	GO:0005547	phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.0	0.1	GO:0004774	succinate-CoA ligase activity(GO:0004774)
0.0	0.1	GO:0001595	angiotensin receptor activity(GO:0001595) angiotensin type II receptor activity(GO:0004945)
0.0	0.3	GO:0015924	mannosyl-oligosaccharide mannosidase activity(GO:0015924)
0.0	0.2	GO:0003857	3-hydroxyacyl-CoA dehydrogenase activity(GO:0003857)
0.0	0.2	GO:0005041	low-density lipoprotein receptor activity(GO:0005041)
0.0	0.1	GO:0004994	somatostatin receptor activity(GO:0004994)
0.0	0.1	GO:0004142	diacylglycerol cholinephosphotransferase activity(GO:0004142)
0.0	0.1	GO:0017159	pantetheine hydrolase activity(GO:0017159)
0.0	0.1	GO:0050542	icosanoid binding(GO:0050542) fatty acid derivative binding(GO:1901567)
0.0	0.3	GO:0010181	FMN binding(GO:0010181)
0.0	0.1	GO:0016174	NAD(P)H oxidase activity(GO:0016174)
0.0	0.1	GO:0016286	small conductance calcium-activated potassium channel activity(GO:0016286)
0.0	0.1	GO:0001012	transcription regulatory region sequence-specific DNA binding(GO:0000976) RNA polymerase II regulatory region sequence-specific DNA binding(GO:0000977) RNA polymerase II regulatory region DNA binding(GO:0001012)
0.0	0.1	GO:0005314	high-affinity glutamate transmembrane transporter activity(GO:0005314)
0.0	0.2	GO:0015347	sodium-independent organic anion transmembrane transporter activity(GO:0015347)
0.0	0.2	GO:0004550	nucleoside diphosphate kinase activity(GO:0004550)
0.0	0.2	GO:0051635	obsolete bacterial cell surface binding(GO:0051635)
0.0	0.1	GO:0004047	aminomethyltransferase activity(GO:0004047)
0.0	0.1	GO:0005094	Rho GDP-dissociation inhibitor activity(GO:0005094)
0.0	0.1	GO:0004167	dopachrome isomerase activity(GO:0004167)
0.0	0.2	GO:0019864	IgG binding(GO:0019864)
0.0	0.1	GO:0046974	histone methyltransferase activity (H3-K9 specific)(GO:0046974)
0.0	0.2	GO:0034593	phosphatidylinositol bisphosphate phosphatase activity(GO:0034593)
0.0	0.1	GO:0042289	MHC class II protein binding(GO:0042289)
0.0	0.3	GO:0019534	toxin transporter activity(GO:0019534)
0.0	0.1	GO:0008273	calcium, potassium:sodium antiporter activity(GO:0008273)
0.0	0.6	GO:0003725	double-stranded RNA binding(GO:0003725)
0.0	0.1	GO:0016530	metallochaperone activity(GO:0016530)
0.0	0.1	GO:0070653	high-density lipoprotein particle receptor binding(GO:0070653)
0.0	0.1	GO:0004459	L-lactate dehydrogenase activity(GO:0004459)
0.0	0.1	GO:0016416	carnitine O-palmitoyltransferase activity(GO:0004095) O-palmitoyltransferase activity(GO:0016416)
0.0	0.1	GO:0004985	opioid receptor activity(GO:0004985)
0.0	0.2	GO:0005522	profilin binding(GO:0005522)
0.0	0.1	GO:0015193	L-proline transmembrane transporter activity(GO:0015193)
0.0	0.1	GO:0004833	tryptophan 2,3-dioxygenase activity(GO:0004833)
0.0	0.2	GO:0030159	receptor signaling complex scaffold activity(GO:0030159)
0.0	0.1	GO:0004301	epoxide hydrolase activity(GO:0004301)
0.0	0.1	GO:0004566	beta-glucuronidase activity(GO:0004566)
0.0	0.3	GO:0008484	sulfuric ester hydrolase activity(GO:0008484)
0.0	0.3	GO:0004708	MAP kinase kinase activity(GO:0004708)
0.0	0.2	GO:0030280	structural constituent of epidermis(GO:0030280)
0.0	0.3	GO:0031593	polyubiquitin binding(GO:0031593)
0.0	0.1	GO:0070053	thrombospondin receptor activity(GO:0070053)
0.0	1.0	GO:0008301	DNA binding, bending(GO:0008301)
0.0	0.1	GO:0051192	ACP phosphopantetheine attachment site binding involved in fatty acid biosynthetic process(GO:0000036) ACP phosphopantetheine attachment site binding(GO:0044620) prosthetic group binding(GO:0051192)
0.0	0.1	GO:0004767	sphingomyelin phosphodiesterase activity(GO:0004767)
0.0	0.0	GO:0035173	histone kinase activity(GO:0035173)
0.0	0.2	GO:0004602	glutathione peroxidase activity(GO:0004602)
0.0	0.3	GO:0002039	p53 binding(GO:0002039)
0.0	0.2	GO:0005246	calcium channel regulator activity(GO:0005246)
0.0	0.1	GO:0000832	inositol hexakisphosphate kinase activity(GO:0000828) inositol hexakisphosphate 5-kinase activity(GO:0000832)
0.0	0.1	GO:0005087	Ran guanyl-nucleotide exchange factor activity(GO:0005087)
0.0	0.1	GO:0046790	virion binding(GO:0046790)
0.0	0.1	GO:0004738	pyruvate dehydrogenase activity(GO:0004738) pyruvate dehydrogenase (acetyl-transferring) activity(GO:0004739)
0.0	0.0	GO:0008179	adenylate cyclase binding(GO:0008179)
0.0	0.0	GO:0030229	very-low-density lipoprotein particle receptor activity(GO:0030229)
0.0	0.1	GO:0003988	acetyl-CoA C-acyltransferase activity(GO:0003988)
0.0	0.1	GO:0005251	delayed rectifier potassium channel activity(GO:0005251)
0.0	0.1	GO:0031014	troponin T binding(GO:0031014)
0.0	0.1	GO:0016857	racemase and epimerase activity, acting on carbohydrates and derivatives(GO:0016857)
0.0	0.1	GO:0043422	protein kinase B binding(GO:0043422)
0.0	0.1	GO:0008409	5'-3' exonuclease activity(GO:0008409)
0.0	0.0	GO:0016453	C-acetyltransferase activity(GO:0016453)
0.0	0.1	GO:0042156	obsolete zinc-mediated transcriptional activator activity(GO:0042156)
0.0	0.1	GO:0005521	lamin binding(GO:0005521)
0.0	0.1	GO:0050664	oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor(GO:0050664)
0.0	0.1	GO:0070491	repressing transcription factor binding(GO:0070491)
0.0	0.3	GO:0070001	aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001)
0.0	0.1	GO:0003917	DNA topoisomerase type I activity(GO:0003917)
0.0	0.1	GO:0047631	ADP-ribose diphosphatase activity(GO:0047631)
0.0	0.1	GO:0008331	high voltage-gated calcium channel activity(GO:0008331)
0.0	0.8	GO:0042393	histone binding(GO:0042393)
0.0	0.0	GO:0004514	nicotinate-nucleotide diphosphorylase (carboxylating) activity(GO:0004514)
0.0	0.0	GO:0008821	crossover junction endodeoxyribonuclease activity(GO:0008821)
0.0	0.1	GO:0008467	[heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.0	0.1	GO:0008553	hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.0	0.1	GO:0080025	phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.0	0.0	GO:0017056	structural constituent of nuclear pore(GO:0017056)
0.0	0.1	GO:0015467	G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.0	0.2	GO:0051059	NF-kappaB binding(GO:0051059)
0.0	0.2	GO:0032452	histone demethylase activity(GO:0032452)
0.0	0.1	GO:0005047	signal recognition particle binding(GO:0005047)
0.0	0.0	GO:0034481	chondroitin sulfotransferase activity(GO:0034481)
0.0	0.0	GO:0016886	ligase activity, forming phosphoric ester bonds(GO:0016886)
0.0	0.1	GO:0008889	glycerophosphodiester phosphodiesterase activity(GO:0008889)
0.0	0.1	GO:0016670	oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor(GO:0016670)
0.0	0.1	GO:0003906	DNA-(apurinic or apyrimidinic site) lyase activity(GO:0003906)
0.0	0.1	GO:0001228	transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0000982) transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077) transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.0	0.1	GO:0070567	cytidylyltransferase activity(GO:0070567)
0.0	0.2	GO:0019205	nucleobase-containing compound kinase activity(GO:0019205)
0.0	0.0	GO:1990939	ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574) ATP-dependent microtubule motor activity(GO:1990939)
0.0	0.0	GO:0005275	amine transmembrane transporter activity(GO:0005275)
0.0	0.1	GO:0008073	ornithine decarboxylase inhibitor activity(GO:0008073)
0.0	0.0	GO:0035514	DNA demethylase activity(GO:0035514) DNA-N1-methyladenine dioxygenase activity(GO:0043734)
0.0	0.0	GO:0030911	TPR domain binding(GO:0030911)
0.0	0.2	GO:0001619	obsolete lysosphingolipid and lysophosphatidic acid receptor activity(GO:0001619)
0.0	0.2	GO:0005487	nucleocytoplasmic transporter activity(GO:0005487)
0.0	0.2	GO:0046875	ephrin receptor binding(GO:0046875)
0.0	0.1	GO:0017169	CDP-alcohol phosphatidyltransferase activity(GO:0017169)
0.0	0.0	GO:0000064	L-ornithine transmembrane transporter activity(GO:0000064)
0.0	0.8	GO:0004197	cysteine-type endopeptidase activity(GO:0004197)
0.0	1.0	GO:0008565	protein transporter activity(GO:0008565)
0.0	0.2	GO:0005164	tumor necrosis factor receptor binding(GO:0005164)
0.0	0.1	GO:0030020	extracellular matrix structural constituent conferring tensile strength(GO:0030020)
0.0	0.3	GO:0004181	metallocarboxypeptidase activity(GO:0004181)
0.0	0.1	GO:0003997	acyl-CoA oxidase activity(GO:0003997)
0.0	0.2	GO:0003756	protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864)
0.0	0.1	GO:0008195	phosphatidate phosphatase activity(GO:0008195)
0.0	0.1	GO:0004596	peptide alpha-N-acetyltransferase activity(GO:0004596)
0.0	0.1	GO:0004594	pantothenate kinase activity(GO:0004594)
0.0	0.0	GO:0016882	cyclo-ligase activity(GO:0016882)
0.0	0.2	GO:0050699	WW domain binding(GO:0050699)
0.0	0.1	GO:0017110	nucleoside-diphosphatase activity(GO:0017110)
0.0	0.0	GO:0019531	oxalate transmembrane transporter activity(GO:0019531)
0.0	0.2	GO:0004143	diacylglycerol kinase activity(GO:0004143)
0.0	0.0	GO:0005092	GDP-dissociation inhibitor activity(GO:0005092)
0.0	0.0	GO:0031434	mitogen-activated protein kinase kinase binding(GO:0031434)
0.0	0.0	GO:0042808	obsolete neuronal Cdc2-like kinase binding(GO:0042808)
0.0	0.0	GO:0008235	metalloexopeptidase activity(GO:0008235)
0.0	0.4	GO:0005044	scavenger receptor activity(GO:0005044)
0.0	0.0	GO:0003953	NAD+ nucleosidase activity(GO:0003953)
0.0	0.0	GO:0015272	ATP-activated inward rectifier potassium channel activity(GO:0015272)
0.0	0.1	GO:0003847	1-alkyl-2-acetylglycerophosphocholine esterase activity(GO:0003847)
0.0	0.2	GO:0046933	proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.0	0.0	GO:0004127	cytidylate kinase activity(GO:0004127)
0.0	0.0	GO:0004457	lactate dehydrogenase activity(GO:0004457)
0.0	0.1	GO:0019213	deacetylase activity(GO:0019213)
0.0	0.1	GO:0061659	ubiquitin-ubiquitin ligase activity(GO:0034450) ubiquitin protein ligase activity(GO:0061630) ubiquitin-like protein ligase activity(GO:0061659)
0.0	0.1	GO:0030371	translation repressor activity(GO:0030371)
0.0	0.0	GO:0000400	four-way junction DNA binding(GO:0000400)
0.0	0.0	GO:0015254	glycerol channel activity(GO:0015254)
0.0	0.2	GO:0008483	transaminase activity(GO:0008483)
0.0	0.1	GO:0048365	Rac GTPase binding(GO:0048365)
0.0	0.2	GO:0004889	acetylcholine-activated cation-selective channel activity(GO:0004889)
0.0	0.1	GO:0016409	palmitoyltransferase activity(GO:0016409)
0.0	0.2	GO:0000030	mannosyltransferase activity(GO:0000030)
0.0	0.1	GO:0005132	type I interferon receptor binding(GO:0005132)
0.0	0.2	GO:0016776	phosphotransferase activity, phosphate group as acceptor(GO:0016776)
0.0	0.1	GO:0008171	O-methyltransferase activity(GO:0008171)
0.0	0.2	GO:0004435	phosphatidylinositol phospholipase C activity(GO:0004435)
0.0	0.2	GO:0005484	SNAP receptor activity(GO:0005484)
0.0	0.0	GO:0004427	inorganic diphosphatase activity(GO:0004427)
0.0	0.0	GO:0005412	glucose:sodium symporter activity(GO:0005412)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	5.7	PID CD8 TCR PATHWAY	TCR signaling in naïve CD8+ T cells
0.1	2.0	PID IL2 STAT5 PATHWAY	IL2 signaling events mediated by STAT5
0.1	0.1	PID P38 ALPHA BETA PATHWAY	Regulation of p38-alpha and p38-beta
0.1	1.0	PID TCR PATHWAY	TCR signaling in naïve CD4+ T cells
0.1	0.2	PID INTEGRIN3 PATHWAY	Beta3 integrin cell surface interactions
0.1	0.6	SA PTEN PATHWAY	PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.1	2.3	PID NFAT 3PATHWAY	Role of Calcineurin-dependent NFAT signaling in lymphocytes
0.0	0.1	PID IL5 PATHWAY	IL5-mediated signaling events
0.0	0.0	PID ERBB NETWORK PATHWAY	ErbB receptor signaling network
0.0	0.4	PID RANBP2 PATHWAY	Sumoylation by RanBP2 regulates transcriptional repression
0.0	0.6	PID LPA4 PATHWAY	LPA4-mediated signaling events
0.0	0.1	PID BETA CATENIN DEG PATHWAY	Degradation of beta catenin
0.0	1.0	PID BCR 5PATHWAY	BCR signaling pathway
0.0	0.2	SA FAS SIGNALING	The TNF-type receptor Fas induces apoptosis on ligand binding.
0.0	1.4	PID NFAT TFPATHWAY	Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0	0.2	PID ERBB4 PATHWAY	ErbB4 signaling events
0.0	0.4	SA B CELL RECEPTOR COMPLEXES	Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.0	0.7	PID GMCSF PATHWAY	GMCSF-mediated signaling events
0.0	0.5	PID IL2 1PATHWAY	IL2-mediated signaling events
0.0	0.7	PID MYC PATHWAY	C-MYC pathway
0.0	0.6	SIG PIP3 SIGNALING IN B LYMPHOCYTES	Genes related to PIP3 signaling in B lymphocytes
0.0	0.4	PID ERB GENOMIC PATHWAY	Validated nuclear estrogen receptor beta network
0.0	0.8	PID IL8 CXCR2 PATHWAY	IL8- and CXCR2-mediated signaling events
0.0	0.6	PID TOLL ENDOGENOUS PATHWAY	Endogenous TLR signaling
0.0	0.2	ST TYPE I INTERFERON PATHWAY	Type I Interferon (alpha/beta IFN) Pathway
0.0	0.1	PID INTEGRIN CS PATHWAY	Integrin family cell surface interactions
0.0	0.7	PID FRA PATHWAY	Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0	0.2	ST PHOSPHOINOSITIDE 3 KINASE PATHWAY	PI3K Pathway
0.0	0.7	PID CDC42 REG PATHWAY	Regulation of CDC42 activity
0.0	0.6	PID HDAC CLASSII PATHWAY	Signaling events mediated by HDAC Class II
0.0	0.5	PID EPHRINB REV PATHWAY	Ephrin B reverse signaling
0.0	0.3	SA MMP CYTOKINE CONNECTION	Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0	0.4	PID WNT CANONICAL PATHWAY	Canonical Wnt signaling pathway
0.0	0.4	PID WNT NONCANONICAL PATHWAY	Noncanonical Wnt signaling pathway
0.0	0.4	PID ARF6 PATHWAY	Arf6 signaling events
0.0	0.2	PID NFKAPPAB CANONICAL PATHWAY	Canonical NF-kappaB pathway
0.0	0.2	PID FAS PATHWAY	FAS (CD95) signaling pathway
0.0	0.1	PID CD40 PATHWAY	CD40/CD40L signaling
0.0	0.2	PID TRAIL PATHWAY	TRAIL signaling pathway
0.0	0.3	PID PI3KCI PATHWAY	Class I PI3K signaling events
0.0	0.1	ST INTERFERON GAMMA PATHWAY	Interferon gamma pathway.
0.0	0.6	PID LKB1 PATHWAY	LKB1 signaling events
0.0	0.1	SIG CD40PATHWAYMAP	Genes related to CD40 signaling
0.0	0.1	PID IL1 PATHWAY	IL1-mediated signaling events
0.0	0.4	PID INTEGRIN2 PATHWAY	Beta2 integrin cell surface interactions
0.0	0.0	PID PI3KCI AKT PATHWAY	Class I PI3K signaling events mediated by Akt
0.0	0.1	ST JNK MAPK PATHWAY	JNK MAPK Pathway
0.0	0.1	PID ATR PATHWAY	ATR signaling pathway
0.0	0.0	PID P38 GAMMA DELTA PATHWAY	Signaling mediated by p38-gamma and p38-delta
0.0	0.0	PID INTEGRIN1 PATHWAY	Beta1 integrin cell surface interactions
0.0	0.1	SA G2 AND M PHASES	Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.0	0.3	PID CERAMIDE PATHWAY	Ceramide signaling pathway
0.0	0.1	SA PROGRAMMED CELL DEATH	Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.0	0.1	ST DIFFERENTIATION PATHWAY IN PC12 CELLS	Differentiation Pathway in PC12 Cells; this is a specific case of PAC1 Receptor Pathway.
0.0	0.2	PID DNA PK PATHWAY	DNA-PK pathway in nonhomologous end joining
0.0	0.2	PID SYNDECAN 2 PATHWAY	Syndecan-2-mediated signaling events
0.0	0.1	PID IL2 PI3K PATHWAY	IL2 signaling events mediated by PI3K
0.0	0.1	PID IL3 PATHWAY	IL3-mediated signaling events
0.0	0.0	SIG BCR SIGNALING PATHWAY	Members of the BCR signaling pathway
0.0	0.3	PID ERBB1 INTERNALIZATION PATHWAY	Internalization of ErbB1
0.0	2.2	NABA ECM AFFILIATED	Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0	0.4	PID AR TF PATHWAY	Regulation of Androgen receptor activity
0.0	0.5	PID HNF3B PATHWAY	FOXA2 and FOXA3 transcription factor networks
0.0	0.1	SIG INSULIN RECEPTOR PATHWAY IN CARDIAC MYOCYTES	Genes related to the insulin receptor pathway
0.0	0.2	PID TXA2PATHWAY	Thromboxane A2 receptor signaling
0.0	0.1	ST GAQ PATHWAY	G alpha q Pathway
0.0	0.2	PID HIF1A PATHWAY	Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.0	0.2	ST WNT BETA CATENIN PATHWAY	Wnt/beta-catenin Pathway
0.0	0.2	PID INTEGRIN A4B1 PATHWAY	Alpha4 beta1 integrin signaling events
0.0	0.2	PID IL6 7 PATHWAY	IL6-mediated signaling events
0.0	0.4	PID P53 REGULATION PATHWAY	p53 pathway
0.0	0.2	PID FCER1 PATHWAY	Fc-epsilon receptor I signaling in mast cells
0.0	1.0	PID P53 DOWNSTREAM PATHWAY	Direct p53 effectors
0.0	0.1	PID SYNDECAN 3 PATHWAY	Syndecan-3-mediated signaling events
0.0	0.1	PID KIT PATHWAY	Signaling events mediated by Stem cell factor receptor (c-Kit)
0.0	0.1	PID NETRIN PATHWAY	Netrin-mediated signaling events
0.0	0.0	ST TUMOR NECROSIS FACTOR PATHWAY	Tumor Necrosis Factor Pathway.
0.0	0.1	PID EPHB FWD PATHWAY	EPHB forward signaling
0.0	0.2	PID CONE PATHWAY	Visual signal transduction: Cones

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.5	REACTOME BINDING AND ENTRY OF HIV VIRION	Genes involved in Binding and entry of HIV virion
0.1	1.6	REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS	Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.1	3.0	REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS	Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.1	2.1	REACTOME EFFECTS OF PIP2 HYDROLYSIS	Genes involved in Effects of PIP2 hydrolysis
0.1	1.1	REACTOME GENERATION OF SECOND MESSENGER MOLECULES	Genes involved in Generation of second messenger molecules
0.1	1.2	REACTOME N GLYCAN ANTENNAE ELONGATION	Genes involved in N-Glycan antennae elongation
0.1	0.1	REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS	Genes involved in Elevation of cytosolic Ca2+ levels
0.1	0.7	REACTOME IL 7 SIGNALING	Genes involved in Interleukin-7 signaling
0.1	1.1	REACTOME GPVI MEDIATED ACTIVATION CASCADE	Genes involved in GPVI-mediated activation cascade
0.1	0.3	REACTOME CD28 DEPENDENT VAV1 PATHWAY	Genes involved in CD28 dependent Vav1 pathway
0.1	0.5	REACTOME PROSTANOID LIGAND RECEPTORS	Genes involved in Prostanoid ligand receptors
0.1	0.1	REACTOME E2F MEDIATED REGULATION OF DNA REPLICATION	Genes involved in E2F mediated regulation of DNA replication
0.1	0.1	REACTOME NUCLEOTIDE LIKE PURINERGIC RECEPTORS	Genes involved in Nucleotide-like (purinergic) receptors
0.0	0.2	REACTOME NFKB ACTIVATION THROUGH FADD RIP1 PATHWAY MEDIATED BY CASPASE 8 AND10	Genes involved in NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10
0.0	0.4	REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION	Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.0	0.2	REACTOME REGULATION OF IFNA SIGNALING	Genes involved in Regulation of IFNA signaling
0.0	0.2	REACTOME RIP MEDIATED NFKB ACTIVATION VIA DAI	Genes involved in RIP-mediated NFkB activation via DAI
0.0	0.4	REACTOME E2F ENABLED INHIBITION OF PRE REPLICATION COMPLEX FORMATION	Genes involved in E2F-enabled inhibition of pre-replication complex formation
0.0	0.1	REACTOME IRAK1 RECRUITS IKK COMPLEX	Genes involved in IRAK1 recruits IKK complex
0.0	0.7	REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION	Genes involved in activated TAK1 mediates p38 MAPK activation
0.0	0.4	REACTOME TRAF6 MEDIATED NFKB ACTIVATION	Genes involved in TRAF6 mediated NF-kB activation
0.0	0.4	REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY	Genes involved in Adenylate cyclase activating pathway
0.0	0.3	REACTOME EICOSANOID LIGAND BINDING RECEPTORS	Genes involved in Eicosanoid ligand-binding receptors
0.0	0.8	REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE	Genes involved in Sema4D induced cell migration and growth-cone collapse
0.0	0.6	REACTOME IL RECEPTOR SHC SIGNALING	Genes involved in Interleukin receptor SHC signaling
0.0	0.8	REACTOME REGULATORY RNA PATHWAYS	Genes involved in Regulatory RNA pathways
0.0	0.7	REACTOME SIGNALING BY ROBO RECEPTOR	Genes involved in Signaling by Robo receptor
0.0	0.3	REACTOME DOWNSTREAM TCR SIGNALING	Genes involved in Downstream TCR signaling
0.0	1.7	REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL	Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0	0.3	REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING	Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
0.0	0.5	REACTOME TRAF3 DEPENDENT IRF ACTIVATION PATHWAY	Genes involved in TRAF3-dependent IRF activation pathway
0.0	0.2	REACTOME IL 6 SIGNALING	Genes involved in Interleukin-6 signaling
0.0	0.0	REACTOME ENDOSOMAL VACUOLAR PATHWAY	Genes involved in Endosomal/Vacuolar pathway
0.0	1.5	REACTOME INTERFERON GAMMA SIGNALING	Genes involved in Interferon gamma signaling
0.0	0.3	REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS	Genes involved in Extrinsic Pathway for Apoptosis
0.0	0.5	REACTOME INFLAMMASOMES	Genes involved in Inflammasomes
0.0	0.1	REACTOME CDT1 ASSOCIATION WITH THE CDC6 ORC ORIGIN COMPLEX	Genes involved in CDT1 association with the CDC6:ORC:origin complex
0.0	0.6	REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE	Genes involved in Synthesis of PIPs at the plasma membrane
0.0	0.3	REACTOME THE ROLE OF NEF IN HIV1 REPLICATION AND DISEASE PATHOGENESIS	Genes involved in The role of Nef in HIV-1 replication and disease pathogenesis
0.0	0.4	REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP	Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.0	1.1	REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION	Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.0	0.2	REACTOME IL 2 SIGNALING	Genes involved in Interleukin-2 signaling
0.0	1.2	REACTOME P53 INDEPENDENT G1 S DNA DAMAGE CHECKPOINT	Genes involved in p53-Independent G1/S DNA damage checkpoint
0.0	1.3	REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES	Genes involved in Chemokine receptors bind chemokines
0.0	0.6	REACTOME KERATAN SULFATE KERATIN METABOLISM	Genes involved in Keratan sulfate/keratin metabolism
0.0	0.0	REACTOME DAG AND IP3 SIGNALING	Genes involved in DAG and IP3 signaling
0.0	0.8	REACTOME GLYCOSPHINGOLIPID METABOLISM	Genes involved in Glycosphingolipid metabolism
0.0	0.3	REACTOME P2Y RECEPTORS	Genes involved in P2Y receptors
0.0	0.2	REACTOME PKA MEDIATED PHOSPHORYLATION OF CREB	Genes involved in PKA-mediated phosphorylation of CREB
0.0	0.6	REACTOME COSTIMULATION BY THE CD28 FAMILY	Genes involved in Costimulation by the CD28 family
0.0	0.4	REACTOME CITRIC ACID CYCLE TCA CYCLE	Genes involved in Citric acid cycle (TCA cycle)
0.0	0.4	REACTOME CHONDROITIN SULFATE BIOSYNTHESIS	Genes involved in Chondroitin sulfate biosynthesis
0.0	0.2	REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR	Genes involved in Trafficking and processing of endosomal TLR
0.0	0.4	REACTOME RECYCLING PATHWAY OF L1	Genes involved in Recycling pathway of L1
0.0	0.2	REACTOME SYNTHESIS OF PE	Genes involved in Synthesis of PE
0.0	0.5	REACTOME METAL ION SLC TRANSPORTERS	Genes involved in Metal ion SLC transporters
0.0	0.9	REACTOME VOLTAGE GATED POTASSIUM CHANNELS	Genes involved in Voltage gated Potassium channels
0.0	0.3	REACTOME REGULATION OF AMPK ACTIVITY VIA LKB1	Genes involved in Regulation of AMPK activity via LKB1
0.0	0.1	REACTOME CIRCADIAN CLOCK	Genes involved in Circadian Clock
0.0	0.0	REACTOME CDK MEDIATED PHOSPHORYLATION AND REMOVAL OF CDC6	Genes involved in CDK-mediated phosphorylation and removal of Cdc6
0.0	0.2	REACTOME TRYPTOPHAN CATABOLISM	Genes involved in Tryptophan catabolism
0.0	0.3	REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION	Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.0	0.3	REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS	Genes involved in Trafficking of GluR2-containing AMPA receptors
0.0	0.1	REACTOME DSCAM INTERACTIONS	Genes involved in DSCAM interactions
0.0	0.1	REACTOME CTNNB1 PHOSPHORYLATION CASCADE	Genes involved in Beta-catenin phosphorylation cascade
0.0	0.3	REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS	Genes involved in ABCA transporters in lipid homeostasis
0.0	0.3	REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING	Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.0	0.5	REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS	Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.0	0.2	REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION	Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.0	0.4	REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 3 PROMOTER	Genes involved in RNA Polymerase III Transcription Initiation From Type 3 Promoter
0.0	0.4	REACTOME CHOLESTEROL BIOSYNTHESIS	Genes involved in Cholesterol biosynthesis
0.0	0.8	REACTOME DEFENSINS	Genes involved in Defensins
0.0	0.1	REACTOME PIP3 ACTIVATES AKT SIGNALING	Genes involved in PIP3 activates AKT signaling
0.0	0.3	REACTOME FANCONI ANEMIA PATHWAY	Genes involved in Fanconi Anemia pathway
0.0	0.4	REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS	Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.0	0.4	REACTOME REGULATION OF BETA CELL DEVELOPMENT	Genes involved in Regulation of beta-cell development
0.0	0.2	REACTOME REGULATION OF COMPLEMENT CASCADE	Genes involved in Regulation of Complement cascade
0.0	0.3	REACTOME RORA ACTIVATES CIRCADIAN EXPRESSION	Genes involved in RORA Activates Circadian Expression
0.0	0.1	REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GLP1	Genes involved in Synthesis, Secretion, and Inactivation of Glucagon-like Peptide-1 (GLP-1)
0.0	0.1	REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN	Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.0	0.3	REACTOME DEADENYLATION OF MRNA	Genes involved in Deadenylation of mRNA
0.0	0.2	REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS	Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
0.0	0.0	REACTOME REGULATION OF INSULIN SECRETION BY GLUCAGON LIKE PEPTIDE1	Genes involved in Regulation of Insulin Secretion by Glucagon-like Peptide-1
0.0	0.1	REACTOME RAP1 SIGNALLING	Genes involved in Rap1 signalling
0.0	0.2	REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION	Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.0	0.3	REACTOME KINESINS	Genes involved in Kinesins
0.0	0.3	REACTOME TRANSPORT TO THE GOLGI AND SUBSEQUENT MODIFICATION	Genes involved in Transport to the Golgi and subsequent modification
0.0	0.1	REACTOME ASSEMBLY OF THE PRE REPLICATIVE COMPLEX	Genes involved in Assembly of the pre-replicative complex
0.0	1.3	REACTOME SIGNALING BY RHO GTPASES	Genes involved in Signaling by Rho GTPases
0.0	0.4	REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE	Genes involved in Amino acid transport across the plasma membrane
0.0	0.0	REACTOME DOPAMINE NEUROTRANSMITTER RELEASE CYCLE	Genes involved in Dopamine Neurotransmitter Release Cycle
0.0	0.2	REACTOME G0 AND EARLY G1	Genes involved in G0 and Early G1
0.0	0.1	REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE	Genes involved in Synthesis of PIPs at the Golgi membrane
0.0	0.4	REACTOME INWARDLY RECTIFYING K CHANNELS	Genes involved in Inwardly rectifying K+ channels
0.0	0.1	REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION	Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.0	0.2	REACTOME HIGHLY CALCIUM PERMEABLE POSTSYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS	Genes involved in Highly calcium permeable postsynaptic nicotinic acetylcholine receptors
0.0	0.6	REACTOME PACKAGING OF TELOMERE ENDS	Genes involved in Packaging Of Telomere Ends
0.0	0.5	REACTOME MITOCHONDRIAL PROTEIN IMPORT	Genes involved in Mitochondrial Protein Import
0.0	0.2	REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING	Genes involved in Formation of ATP by chemiosmotic coupling
0.0	0.0	REACTOME REGULATED PROTEOLYSIS OF P75NTR	Genes involved in Regulated proteolysis of p75NTR
0.0	0.1	REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN	Genes involved in Platelet Adhesion to exposed collagen
0.0	0.5	REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S	Genes involved in Activation of Chaperone Genes by XBP1(S)
0.0	0.7	REACTOME RESPIRATORY ELECTRON TRANSPORT ATP SYNTHESIS BY CHEMIOSMOTIC COUPLING AND HEAT PRODUCTION BY UNCOUPLING PROTEINS	Genes involved in Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins.
0.0	0.2	REACTOME RIG I MDA5 MEDIATED INDUCTION OF IFN ALPHA BETA PATHWAYS	Genes involved in RIG-I/MDA5 mediated induction of IFN-alpha/beta pathways
0.0	0.1	REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION	Genes involved in Cyclin A/B1 associated events during G2/M transition
0.0	0.2	REACTOME INSULIN SYNTHESIS AND PROCESSING	Genes involved in Insulin Synthesis and Processing
0.0	0.1	REACTOME ETHANOL OXIDATION	Genes involved in Ethanol oxidation
0.0	0.2	REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI	Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.0	0.1	REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION	Genes involved in Apoptosis induced DNA fragmentation
0.0	0.2	REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT	Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.0	0.0	REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK	Genes involved in Negative regulation of the PI3K/AKT network

Results for OSR1_OSR2

Z-value: 2.32

Motif logo

Transcription factors associated with OSR1_OSR2

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

Activity of the OSR1_OSR2 motif across conditions

Conditions sorted by the z-value of the OSR1_OSR2 motif activity

Top target CREs of the motif:

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of OSR1_OSR2

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category:

Gene overrepresentation in curated gene sets: canonical pathways category:

Gene overrepresentation in curated gene sets: REACTOME pathways category: