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ENCODE: H3K4me1 ChIP-Seq of primary human cells
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CREMA is a free online tool that recognizes most important transcription factors that change the chromatin state across different samples.

Results for OSR1_OSR2

Z-value: 2.32

Motif logo

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Transcription factors associated with OSR1_OSR2

Gene Symbol Gene ID Gene Info
ENSG00000143867.5 OSR1
ENSG00000164920.5 OSR2

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE Gene Distance Association probability Pearson corr. coef. P-value Plot
OSR1chr2_19774448_197745992161090.022824-0.951.0e-04Click!
OSR1chr2_19740386_197405371820470.031101-0.835.9e-03Click!
OSR1chr2_19741188_197413391828490.030857-0.836.0e-03Click!
OSR1chr2_19738799_197389501804600.031590-0.801.0e-02Click!
OSR1chr2_19774735_197748862163960.022767-0.771.5e-02Click!
OSR2chr8_99975742_99975893151970.158561-0.713.3e-02Click!
OSR2chr8_99978768_99978919182230.152899-0.713.4e-02Click!
OSR2chr8_99957659_999578388610.5528050.703.6e-02Click!
OSR2chr8_99979066_99979217185210.152327-0.684.4e-02Click!
OSR2chr8_99957338_999576205920.6955020.674.7e-02Click!

Activity of the OSR1_OSR2 motif across conditions

Conditions sorted by the z-value of the OSR1_OSR2 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE) Target Score Top associated gene Gene Info Distance of CRE to TSS CRE/Gene association probability
chr1_117056573_117057331 1.08 CD58
CD58 molecule
30260
0.14
chr5_150595265_150595488 1.03 GM2A
GM2 ganglioside activator
3665
0.22
chr11_117821389_117821783 0.98 TMPRSS13
transmembrane protease, serine 13
21412
0.15
chr1_185646518_185646683 0.92 ENSG00000201596
.
43286
0.15
chr14_61827530_61827767 0.92 PRKCH
protein kinase C, eta
144
0.97
chr22_40329879_40330140 0.91 GRAP2
GRB2-related adaptor protein 2
7368
0.18
chr5_67567518_67567669 0.90 PIK3R1
phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
8475
0.29
chr7_50435924_50436099 0.90 ENSG00000200815
.
67067
0.11
chr2_241504090_241504573 0.89 RNPEPL1
arginyl aminopeptidase (aminopeptidase B)-like 1
890
0.44
chr13_77928416_77928623 0.89 MYCBP2
MYC binding protein 2, E3 ubiquitin protein ligase
27340
0.25
chr5_56137965_56138116 0.88 ENSG00000238717
.
14935
0.15
chr6_37475943_37476266 0.88 CCDC167
coiled-coil domain containing 167
8406
0.21
chr4_99584969_99585255 0.87 RP11-1299A16.3

5057
0.25
chr5_148415725_148415940 0.87 SH3TC2
SH3 domain and tetratricopeptide repeats 2
5277
0.19
chr12_44226149_44226476 0.86 TMEM117
transmembrane protein 117
3574
0.27
chr6_25008850_25009114 0.83 ENSG00000244618
.
22528
0.17
chr7_38348883_38349236 0.81 STARD3NL
STARD3 N-terminal like
131062
0.05
chr1_167602146_167602334 0.80 RP3-455J7.4

2329
0.28
chr14_102283672_102283878 0.80 CTD-2017C7.2

7117
0.15
chr6_91060753_91061282 0.78 ENSG00000266760
.
38556
0.18
chr14_91790763_91791635 0.78 ENSG00000265856
.
8858
0.21
chr14_38547457_38547608 0.76 CTD-2058B24.2

12831
0.26
chr15_73069226_73069377 0.76 ADPGK-AS1
ADPGK antisense RNA 1
5875
0.19
chr16_21659708_21660026 0.75 IGSF6
immunoglobulin superfamily, member 6
4060
0.14
chr16_68104442_68104656 0.75 NFATC3
nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3
14698
0.09
chr1_212968214_212968462 0.74 TATDN3
TatD DNase domain containing 3
313
0.88
chr2_240242275_240242517 0.74 HDAC4
histone deacetylase 4
11489
0.18
chr6_131526099_131526250 0.73 AKAP7
A kinase (PRKA) anchor protein 7
4207
0.36
chr16_3623403_3623748 0.73 NLRC3
NLR family, CARD domain containing 3
3817
0.17
chrX_78408330_78408687 0.73 GPR174
G protein-coupled receptor 174
17961
0.3
chr19_33651116_33651486 0.73 ENSG00000264355
.
16677
0.12
chr1_9485397_9485907 0.73 ENSG00000252956
.
12185
0.23
chr1_148195742_148195893 0.72 PPIAL4D
peptidylprolyl isomerase A (cyclophilin A)-like 4D
6719
0.26
chr1_8532692_8532843 0.72 ENSG00000221083
.
39211
0.15
chr1_14058388_14058781 0.72 PRDM2
PR domain containing 2, with ZNF domain
17314
0.21
chr16_68319061_68319396 0.72 ENSG00000252026
.
1007
0.3
chr22_37618057_37618806 0.71 SSTR3
somatostatin receptor 3
10069
0.13
chr6_147093114_147093265 0.71 ADGB
androglobin
1474
0.55
chr12_21766880_21767202 0.70 GYS2
glycogen synthase 2 (liver)
9260
0.2
chrX_147416060_147416261 0.70 AC002368.4

165975
0.04
chr2_240219157_240219354 0.70 ENSG00000265215
.
7902
0.19
chr2_143910577_143910744 0.69 RP11-190J23.1

19081
0.23
chr1_27156953_27157104 0.69 ZDHHC18
zinc finger, DHHC-type containing 18
1467
0.28
chr7_8004458_8004609 0.69 GLCCI1
glucocorticoid induced transcript 1
3892
0.21
chr15_60688902_60689138 0.69 ANXA2
annexin A2
517
0.85
chr5_150614598_150614909 0.69 CCDC69
coiled-coil domain containing 69
11047
0.18
chr2_69921039_69921201 0.69 ENSG00000238708
.
26629
0.17
chr15_38855420_38855571 0.69 RASGRP1
RAS guanyl releasing protein 1 (calcium and DAG-regulated)
1341
0.45
chr16_89794033_89794184 0.69 ZNF276
zinc finger protein 276
6156
0.1
chr13_22636687_22636838 0.69 ENSG00000244197
.
272086
0.02
chr17_55353882_55354230 0.68 MSI2
musashi RNA-binding protein 2
9149
0.28
chr12_112439406_112439724 0.68 TMEM116
transmembrane protein 116
4224
0.19
chr7_104985736_104986011 0.68 ENSG00000201179
.
12636
0.21
chr22_32538380_32538635 0.68 AP1B1P1
adaptor-related protein complex 1, beta 1 subunit pseudogene 1
10203
0.14
chr10_126418566_126418777 0.68 FAM53B
family with sequence similarity 53, member B
12868
0.17
chr13_49684512_49684663 0.67 FNDC3A
fibronectin type III domain containing 3A
138
0.97
chr22_25782802_25782953 0.67 LRP5L
low density lipoprotein receptor-related protein 5-like
5333
0.23
chr17_38760477_38760676 0.67 SMARCE1
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 1
27966
0.12
chr10_28909030_28909272 0.67 ENSG00000252401
.
32408
0.15
chr2_191281890_191282188 0.66 MFSD6
major facilitator superfamily domain containing 6
8958
0.2
chr4_166207034_166207185 0.66 ENSG00000200974
.
33377
0.15
chr10_28656205_28656487 0.66 MPP7
membrane protein, palmitoylated 7 (MAGUK p55 subfamily member 7)
32931
0.16
chr16_74642212_74642580 0.66 GLG1
golgi glycoprotein 1
1384
0.48
chr15_23027471_23027645 0.66 NIPA2
non imprinted in Prader-Willi/Angelman syndrome 2
6812
0.19
chr1_160674262_160674415 0.66 CD48
CD48 molecule
7255
0.16
chr7_106814622_106814964 0.66 HBP1
HMG-box transcription factor 1
4575
0.23
chr16_79302347_79302574 0.65 ENSG00000222244
.
4109
0.35
chr2_144049594_144049745 0.65 RP11-190J23.1

119928
0.06
chrX_71322805_71323092 0.65 RGAG4
retrotransposon gag domain containing 4
28730
0.14
chr1_111727930_111728149 0.64 RP5-1180E21.5

356
0.8
chr16_68272603_68272754 0.64 ESRP2
epithelial splicing regulatory protein 2
673
0.38
chr2_204596754_204596977 0.64 CD28
CD28 molecule
25449
0.18
chr1_25311538_25311783 0.64 RUNX3
runt-related transcription factor 3
20159
0.18
chr18_13437855_13438006 0.64 LDLRAD4-AS1
LDLRAD4 antisense RNA 1
10451
0.12
chr1_19806357_19806811 0.63 CAPZB
capping protein (actin filament) muscle Z-line, beta
3995
0.2
chr21_46341039_46341644 0.63 ITGB2-AS1
ITGB2 antisense RNA 1
100
0.73
chr10_48454539_48454690 0.63 GDF10
growth differentiation factor 10
15638
0.18
chr9_82220589_82220740 0.63 TLE4
transducin-like enhancer of split 4 (E(sp1) homolog, Drosophila)
32060
0.26
chr5_171551377_171551636 0.63 ENSG00000266671
.
43526
0.14
chr7_127440050_127440201 0.63 SND1
staphylococcal nuclease and tudor domain containing 1
87840
0.09
chr4_153380478_153380731 0.63 ENSG00000264678
.
29964
0.18
chr5_80036862_80037122 0.63 DHFR
dihydrofolate reductase
86190
0.08
chr6_36487291_36487442 0.63 ENSG00000239964
.
2602
0.21
chr1_117548818_117548969 0.63 CD101
CD101 molecule
4459
0.2
chr16_81503047_81503332 0.62 CMIP
c-Maf inducing protein
24414
0.23
chr19_1087607_1087865 0.62 POLR2E
polymerase (RNA) II (DNA directed) polypeptide E, 25kDa
7617
0.09
chr17_74139221_74139800 0.62 RNF157-AS1
RNF157 antisense RNA 1
1913
0.2
chr15_64919513_64919664 0.62 ENSG00000207223
.
25499
0.13
chr4_3197251_3197402 0.62 HTT
huntingtin
35237
0.17
chr15_38976198_38976376 0.62 C15orf53
chromosome 15 open reading frame 53
12512
0.28
chr1_160603209_160603365 0.62 SLAMF1
signaling lymphocytic activation molecule family member 1
13524
0.15
chrX_131618048_131618256 0.61 MBNL3
muscleblind-like splicing regulator 3
4891
0.32
chr11_81674020_81674171 0.61 ENSG00000264110
.
72217
0.14
chr10_135202816_135202986 0.61 RP11-108K14.8
Mitochondrial GTPase 1
1437
0.21
chr11_68097923_68098433 0.60 LRP5
low density lipoprotein receptor-related protein 5
18101
0.21
chrX_18588475_18588626 0.60 RS1
retinoschisin 1
101679
0.07
chr1_117101191_117101451 0.60 ENSG00000264419
.
1412
0.39
chr1_108492854_108493265 0.60 VAV3-AS1
VAV3 antisense RNA 1
14006
0.21
chr1_206747367_206748212 0.60 RASSF5
Ras association (RalGDS/AF-6) domain family member 5
17296
0.15
chr5_80300013_80300264 0.60 CTC-459I6.1

43412
0.16
chr6_35278431_35279308 0.60 DEF6
differentially expressed in FDCP 6 homolog (mouse)
1354
0.42
chr2_240152782_240153089 0.59 HDAC4
histone deacetylase 4
40183
0.13
chr11_34385617_34385918 0.59 ABTB2
ankyrin repeat and BTB (POZ) domain containing 2
6212
0.28
chr2_114457524_114457975 0.59 ENSG00000202427
.
19061
0.16
chr11_4090490_4090712 0.59 STIM1
stromal interaction molecule 1
5148
0.22
chr9_129285864_129286127 0.59 ENSG00000221768
.
7275
0.22
chr1_100913408_100913559 0.59 RP5-837M10.4

38070
0.16
chr1_112020337_112020708 0.59 C1orf162
chromosome 1 open reading frame 162
4031
0.12
chr3_4888757_4888908 0.59 ENSG00000239126
.
31554
0.17
chr14_92327065_92327275 0.59 TC2N
tandem C2 domains, nuclear
6703
0.21
chr17_2171475_2171819 0.58 SMG6
SMG6 nonsense mediated mRNA decay factor
2154
0.21
chr16_28209700_28209851 0.58 XPO6
exportin 6
13022
0.17
chr13_79975678_79975862 0.58 RBM26
RNA binding motif protein 26
4153
0.21
chr14_52784751_52784902 0.58 PTGER2
prostaglandin E receptor 2 (subtype EP2), 53kDa
3713
0.31
chr8_103810651_103810802 0.58 AZIN1
antizyme inhibitor 1
59604
0.1
chr5_118615599_118615750 0.58 TNFAIP8
tumor necrosis factor, alpha-induced protein 8
11225
0.18
chr6_112170750_112170901 0.58 FYN
FYN oncogene related to SRC, FGR, YES
3007
0.37
chr13_100035601_100035752 0.58 ENSG00000207719
.
27291
0.18
chr16_50304697_50304944 0.58 ADCY7
adenylate cyclase 7
3244
0.27
chr15_85303810_85304154 0.58 RP11-7M10.2

7629
0.15
chr19_54376046_54376205 0.58 MYADM
myeloid-associated differentiation marker
3106
0.09
chr1_118157265_118157675 0.58 FAM46C
family with sequence similarity 46, member C
8914
0.22
chr15_75090176_75090431 0.58 CSK
c-src tyrosine kinase
48
0.96
chr4_36327248_36327457 0.57 DTHD1
death domain containing 1
41708
0.17
chr17_78846780_78847058 0.57 RPTOR
regulatory associated protein of MTOR, complex 1
49605
0.11
chrX_129222301_129222452 0.57 ELF4
E74-like factor 4 (ets domain transcription factor)
21960
0.19
chr14_36235989_36236257 0.57 ENSG00000253059
.
10590
0.16
chr4_166215238_166215389 0.57 MSMO1
methylsterol monooxygenase 1
33462
0.15
chr15_34620468_34620619 0.57 SLC12A6
solute carrier family 12 (potassium/chloride transporter), member 6
8502
0.12
chrX_70328164_70328598 0.57 IL2RG
interleukin 2 receptor, gamma
737
0.47
chr1_111186012_111186163 0.56 ENSG00000221538
.
9566
0.18
chr8_125499989_125500140 0.56 RP11-158K1.3

687
0.64
chr11_45047514_45047716 0.56 PRDM11
PR domain containing 11
67949
0.12
chr12_92796420_92796828 0.56 RP11-693J15.4

18683
0.18
chr15_60877657_60877957 0.56 RORA
RAR-related orphan receptor A
6933
0.24
chr1_112190134_112190365 0.56 ENSG00000201028
.
2910
0.25
chrX_13016516_13016803 0.56 TMSB4X
thymosin beta 4, X-linked
22882
0.2
chr16_3917043_3917313 0.56 CREBBP
CREB binding protein
12943
0.21
chr7_148544637_148544788 0.56 ENSG00000251712
.
26608
0.14
chr11_128644504_128644655 0.56 FLI1
Fli-1 proto-oncogene, ETS transcription factor
9894
0.22
chr4_15609696_15609847 0.56 FBXL5
F-box and leucine-rich repeat protein 5
36501
0.15
chr12_51718815_51719232 0.55 BIN2
bridging integrator 2
571
0.71
chrX_71336501_71336652 0.55 RGAG4
retrotransposon gag domain containing 4
15102
0.16
chr6_11710027_11710178 0.55 ENSG00000207419
.
50
0.98
chr8_6582802_6582976 0.55 AGPAT5
1-acylglycerol-3-phosphate O-acyltransferase 5
16675
0.17
chr19_8813606_8813968 0.55 ACTL9
actin-like 9
4615
0.22
chr14_91877682_91877988 0.55 CCDC88C
coiled-coil domain containing 88C
5855
0.26
chr8_19553467_19553618 0.55 CSGALNACT1
chondroitin sulfate N-acetylgalactosaminyltransferase 1
13270
0.29
chr17_74175074_74175225 0.55 RNF157
ring finger protein 157
11986
0.13
chr7_36663254_36663529 0.55 ENSG00000221561
.
18458
0.18
chr6_139572992_139573163 0.54 TXLNB
taxilin beta
10657
0.19
chr1_11307359_11307510 0.54 MTOR
mechanistic target of rapamycin (serine/threonine kinase)
15130
0.14
chr10_11236679_11236947 0.54 RP3-323N1.2

23474
0.2
chr13_77312950_77313101 0.54 KCTD12
potassium channel tetramerization domain containing 12
147500
0.04
chr16_50801742_50801950 0.54 CYLD
cylindromatosis (turban tumor syndrome)
18386
0.11
chr1_26441433_26441584 0.54 PDIK1L
PDLIM1 interacting kinase 1 like
3168
0.15
chr2_171508638_171509172 0.54 AC007277.3

8451
0.23
chr22_23207531_23207682 0.54 IGLV4-3
immunoglobulin lambda variable 4-3
6080
0.05
chr4_128554514_128554677 0.54 INTU
inturned planar cell polarity protein
475
0.88
chr5_75840980_75841213 0.53 IQGAP2
IQ motif containing GTPase activating protein 2
2138
0.39
chr7_55541540_55541796 0.53 VOPP1
vesicular, overexpressed in cancer, prosurvival protein 1
42102
0.18
chr3_108551834_108551998 0.53 TRAT1
T cell receptor associated transmembrane adaptor 1
10297
0.26
chr14_93120739_93120918 0.53 RIN3
Ras and Rab interactor 3
1982
0.44
chr8_128192126_128192325 0.53 POU5F1B
POU class 5 homeobox 1B
234310
0.02
chr10_103815226_103815416 0.53 C10orf76
chromosome 10 open reading frame 76
629
0.68
chr4_109081453_109081912 0.53 LEF1
lymphoid enhancer-binding factor 1
5775
0.24
chr10_50397490_50397641 0.52 C10orf128
chromosome 10 open reading frame 128
1129
0.52
chr4_144325483_144325634 0.52 GAB1
GRB2-associated binding protein 1
12895
0.23
chr5_49624115_49624266 0.52 EMB
embigin
100371
0.09
chr6_130537662_130538085 0.52 SAMD3
sterile alpha motif domain containing 3
794
0.75
chr22_39545331_39545521 0.52 CBX7
chromobox homolog 7
3023
0.22
chr20_51610177_51610328 0.52 TSHZ2
teashirt zinc finger homeobox 2
21306
0.24
chrX_78413004_78413155 0.52 GPR174
G protein-coupled receptor 174
13390
0.31
chr7_150705681_150705832 0.52 NOS3
nitric oxide synthase 3 (endothelial cell)
269
0.84
chr22_40305396_40305614 0.52 GRAP2
GRB2-related adaptor protein 2
8392
0.18
chr2_88327551_88327940 0.52 ENSG00000222724
.
11679
0.14
chr2_232410029_232410622 0.52 NMUR1
neuromedin U receptor 1
15119
0.14
chr2_106804645_106804858 0.52 UXS1
UDP-glucuronate decarboxylase 1
6004
0.25
chr22_40484830_40485057 0.52 TNRC6B
trinucleotide repeat containing 6B
43465
0.14
chr1_67677903_67678054 0.52 IL23R
interleukin 23 receptor
4629
0.17
chr1_8683787_8683941 0.52 RERE
arginine-glutamic acid dipeptide (RE) repeats
575
0.83
chr10_111929980_111930210 0.52 MXI1
MAX interactor 1, dimerization protein
37268
0.17
chr5_112354195_112354393 0.52 DCP2
decapping mRNA 2
41815
0.16
chr17_73396861_73397043 0.51 GRB2
growth factor receptor-bound protein 2
4615
0.1
chr2_136893266_136893435 0.51 CXCR4
chemokine (C-X-C motif) receptor 4
17615
0.27
chr4_90166750_90166901 0.51 GPRIN3
GPRIN family member 3
5520
0.31
chr3_111264164_111264389 0.51 CD96
CD96 molecule
3279
0.32
chrX_101914217_101914428 0.51 RP4-769N13.7

318
0.86
chrX_11779477_11779642 0.51 MSL3
male-specific lethal 3 homolog (Drosophila)
1812
0.5
chr1_25992814_25992965 0.51 RP1-187B23.1

7287
0.2
chr8_49862673_49862887 0.51 SNAI2
snail family zinc finger 2
28481
0.25
chr3_69106553_69106704 0.51 TMF1
TATA element modulatory factor 1
5144
0.15
chr5_75701847_75702137 0.51 IQGAP2
IQ motif containing GTPase activating protein 2
1743
0.49
chr6_152024316_152024467 0.51 ESR1
estrogen receptor 1
12760
0.26
chr11_85763685_85763836 0.51 PICALM
phosphatidylinositol binding clathrin assembly protein
16062
0.21
chr7_4725664_4725895 0.51 ENSG00000238781
.
3332
0.25
chr3_186743418_186743719 0.51 ST6GAL1
ST6 beta-galactosamide alpha-2,6-sialyltranferase 1
297
0.93
chrX_128911606_128911929 0.51 SASH3
SAM and SH3 domain containing 3
2193
0.32
chr3_32345545_32345886 0.51 ENSG00000207857
.
44495
0.14
chr4_54277446_54277597 0.51 FIP1L1
factor interacting with PAPOLA and CPSF1
16712
0.22

Histogram of CRE-TSS distances for CREs targeted by :

Histogram of

Rank distribution of CRE target scores:

Histogram of target CRE score.

Distribution of target CREs across different genomic regions:

Weighted Piechart of Weighted Piechart of Weighted Piechart of

Network of associatons between targets according to the STRING database.

StringDB image

First level regulatory network of OSR1_OSR2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.8 GO:0048742 regulation of skeletal muscle fiber development(GO:0048742)
0.2 0.8 GO:0030854 positive regulation of granulocyte differentiation(GO:0030854)
0.2 0.7 GO:1901339 activation of store-operated calcium channel activity(GO:0032237) regulation of store-operated calcium channel activity(GO:1901339) positive regulation of store-operated calcium channel activity(GO:1901341)
0.2 0.6 GO:0031340 positive regulation of vesicle fusion(GO:0031340)
0.1 0.4 GO:0046449 allantoin metabolic process(GO:0000255) creatinine metabolic process(GO:0046449) cellular lactam metabolic process(GO:0072338)
0.1 0.4 GO:0071224 cellular response to peptidoglycan(GO:0071224)
0.1 0.4 GO:0034638 phosphatidylcholine catabolic process(GO:0034638)
0.1 0.3 GO:0045341 MHC class I biosynthetic process(GO:0045341) regulation of MHC class I biosynthetic process(GO:0045343)
0.1 0.6 GO:0031061 negative regulation of histone methylation(GO:0031061)
0.1 0.5 GO:0045589 regulation of regulatory T cell differentiation(GO:0045589)
0.1 0.1 GO:0002677 negative regulation of chronic inflammatory response(GO:0002677)
0.1 0.5 GO:0009313 oligosaccharide catabolic process(GO:0009313)
0.1 0.4 GO:0003056 regulation of vascular smooth muscle contraction(GO:0003056)
0.1 0.1 GO:0006269 DNA replication, synthesis of RNA primer(GO:0006269)
0.1 1.0 GO:0002507 tolerance induction(GO:0002507)
0.1 0.3 GO:0031946 regulation of glucocorticoid biosynthetic process(GO:0031946)
0.1 0.2 GO:0046642 negative regulation of alpha-beta T cell proliferation(GO:0046642)
0.1 0.3 GO:0010956 negative regulation of calcidiol 1-monooxygenase activity(GO:0010956) negative regulation of vitamin D biosynthetic process(GO:0010957) negative regulation of vitamin metabolic process(GO:0046137)
0.1 0.3 GO:0042091 interleukin-10 biosynthetic process(GO:0042091) regulation of interleukin-10 biosynthetic process(GO:0045074)
0.1 0.4 GO:0031282 regulation of guanylate cyclase activity(GO:0031282)
0.1 0.5 GO:0050857 positive regulation of antigen receptor-mediated signaling pathway(GO:0050857)
0.1 0.2 GO:0010572 positive regulation of platelet activation(GO:0010572)
0.1 1.1 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.1 0.3 GO:0010459 negative regulation of heart rate(GO:0010459)
0.1 0.3 GO:0001766 membrane raft polarization(GO:0001766) membrane raft distribution(GO:0031580)
0.1 0.3 GO:0006089 lactate metabolic process(GO:0006089)
0.1 0.2 GO:0045066 regulatory T cell differentiation(GO:0045066)
0.1 0.5 GO:0060009 Sertoli cell development(GO:0060009)
0.1 0.3 GO:0035066 positive regulation of histone acetylation(GO:0035066) positive regulation of protein acetylation(GO:1901985) positive regulation of peptidyl-lysine acetylation(GO:2000758)
0.1 0.3 GO:0035610 C-terminal protein deglutamylation(GO:0035609) protein side chain deglutamylation(GO:0035610)
0.1 0.3 GO:0007042 lysosomal lumen acidification(GO:0007042) regulation of lysosomal lumen pH(GO:0035751)
0.1 0.6 GO:0001562 response to protozoan(GO:0001562)
0.1 1.0 GO:0032653 regulation of interleukin-10 production(GO:0032653)
0.1 0.2 GO:0019276 UDP-N-acetylgalactosamine metabolic process(GO:0019276)
0.1 0.1 GO:0010915 regulation of very-low-density lipoprotein particle clearance(GO:0010915) negative regulation of very-low-density lipoprotein particle clearance(GO:0010916)
0.1 0.2 GO:0046548 retinal rod cell development(GO:0046548)
0.1 0.2 GO:0006610 ribosomal protein import into nucleus(GO:0006610)
0.1 0.2 GO:0015917 aminophospholipid transport(GO:0015917)
0.1 0.4 GO:0007172 signal complex assembly(GO:0007172)
0.1 0.1 GO:0003100 regulation of systemic arterial blood pressure by endothelin(GO:0003100)
0.1 0.1 GO:0032814 regulation of natural killer cell activation(GO:0032814)
0.1 0.1 GO:0061030 epithelial cell differentiation involved in mammary gland alveolus development(GO:0061030)
0.1 0.2 GO:0045163 clustering of voltage-gated potassium channels(GO:0045163)
0.1 0.3 GO:0034755 iron ion transmembrane transport(GO:0034755)
0.1 0.1 GO:0034983 peptidyl-lysine deacetylation(GO:0034983)
0.1 0.3 GO:0042989 sequestering of actin monomers(GO:0042989)
0.1 0.5 GO:0051491 positive regulation of filopodium assembly(GO:0051491)
0.1 0.2 GO:0034626 fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.1 0.1 GO:0014742 positive regulation of cardiac muscle hypertrophy(GO:0010613) positive regulation of muscle hypertrophy(GO:0014742)
0.1 0.2 GO:0048478 replication fork protection(GO:0048478)
0.1 0.3 GO:0045056 transcytosis(GO:0045056)
0.1 0.6 GO:0006906 vesicle fusion(GO:0006906)
0.1 0.2 GO:0042420 dopamine catabolic process(GO:0042420)
0.1 0.4 GO:0008653 lipopolysaccharide metabolic process(GO:0008653)
0.1 0.1 GO:0048541 Peyer's patch development(GO:0048541)
0.1 0.2 GO:0006007 glucose catabolic process(GO:0006007)
0.1 0.8 GO:0000305 response to oxygen radical(GO:0000305)
0.1 0.2 GO:1901978 positive regulation of spindle checkpoint(GO:0090232) regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090266) positive regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090267) positive regulation of cell cycle checkpoint(GO:1901978) regulation of mitotic spindle checkpoint(GO:1903504)
0.1 0.2 GO:0001787 natural killer cell proliferation(GO:0001787)
0.1 0.2 GO:0002407 dendritic cell chemotaxis(GO:0002407) dendritic cell migration(GO:0036336)
0.1 0.1 GO:0030223 neutrophil differentiation(GO:0030223)
0.1 0.4 GO:0050858 negative regulation of antigen receptor-mediated signaling pathway(GO:0050858) negative regulation of T cell receptor signaling pathway(GO:0050860)
0.1 3.5 GO:0050852 T cell receptor signaling pathway(GO:0050852)
0.1 0.2 GO:0035405 histone-threonine phosphorylation(GO:0035405)
0.1 0.2 GO:0070102 interleukin-6-mediated signaling pathway(GO:0070102)
0.1 0.2 GO:0003078 obsolete regulation of natriuresis(GO:0003078)
0.1 0.2 GO:0045654 positive regulation of megakaryocyte differentiation(GO:0045654) positive regulation of hematopoietic progenitor cell differentiation(GO:1901534)
0.1 0.1 GO:0045986 negative regulation of smooth muscle contraction(GO:0045986)
0.1 0.2 GO:0043320 natural killer cell activation involved in immune response(GO:0002323) natural killer cell degranulation(GO:0043320)
0.1 0.2 GO:0071921 establishment of sister chromatid cohesion(GO:0034085) cohesin loading(GO:0071921) regulation of cohesin loading(GO:0071922)
0.1 0.2 GO:0006678 glucosylceramide metabolic process(GO:0006678)
0.1 0.1 GO:1903053 regulation of extracellular matrix disassembly(GO:0010715) negative regulation of extracellular matrix disassembly(GO:0010716) regulation of extracellular matrix organization(GO:1903053) negative regulation of extracellular matrix organization(GO:1903054)
0.1 0.2 GO:0033152 immunoglobulin V(D)J recombination(GO:0033152)
0.1 0.6 GO:0070536 protein K63-linked deubiquitination(GO:0070536)
0.1 0.1 GO:0032071 regulation of endodeoxyribonuclease activity(GO:0032071)
0.1 0.2 GO:0042339 keratan sulfate metabolic process(GO:0042339)
0.1 0.2 GO:0001821 histamine secretion(GO:0001821)
0.1 0.1 GO:0002888 positive regulation of myeloid leukocyte mediated immunity(GO:0002888)
0.0 0.1 GO:0000733 DNA strand renaturation(GO:0000733)
0.0 0.1 GO:0045416 positive regulation of interleukin-8 biosynthetic process(GO:0045416)
0.0 0.2 GO:0043984 histone H4-K16 acetylation(GO:0043984)
0.0 0.1 GO:0018076 N-terminal peptidyl-lysine acetylation(GO:0018076)
0.0 0.2 GO:0007256 activation of JNKK activity(GO:0007256)
0.0 0.0 GO:0032509 endosome transport via multivesicular body sorting pathway(GO:0032509)
0.0 0.7 GO:0050832 defense response to fungus(GO:0050832)
0.0 0.2 GO:0043951 negative regulation of cAMP-mediated signaling(GO:0043951)
0.0 0.1 GO:0002523 leukocyte migration involved in inflammatory response(GO:0002523)
0.0 0.1 GO:0046398 UDP-glucuronate metabolic process(GO:0046398)
0.0 0.1 GO:0042663 endodermal cell fate specification(GO:0001714) regulation of endodermal cell fate specification(GO:0042663) regulation of endodermal cell differentiation(GO:1903224)
0.0 0.1 GO:0090075 relaxation of muscle(GO:0090075)
0.0 0.0 GO:0032278 positive regulation of gonadotropin secretion(GO:0032278) positive regulation of follicle-stimulating hormone secretion(GO:0046881)
0.0 0.5 GO:0016045 detection of bacterium(GO:0016045)
0.0 0.0 GO:0090205 positive regulation of cholesterol metabolic process(GO:0090205)
0.0 0.4 GO:0036230 granulocyte activation(GO:0036230)
0.0 0.0 GO:0046007 negative regulation of activated T cell proliferation(GO:0046007)
0.0 0.0 GO:0045759 negative regulation of action potential(GO:0045759)
0.0 0.1 GO:0034219 carbohydrate transmembrane transport(GO:0034219)
0.0 0.1 GO:0033345 asparagine catabolic process(GO:0006530) asparagine catabolic process via L-aspartate(GO:0033345)
0.0 0.1 GO:0051657 maintenance of organelle location(GO:0051657)
0.0 0.1 GO:0050955 thermoception(GO:0050955)
0.0 0.3 GO:0001782 B cell homeostasis(GO:0001782)
0.0 0.2 GO:0015760 hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760)
0.0 0.1 GO:0060528 secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development(GO:0060528)
0.0 0.0 GO:0016080 synaptic vesicle targeting(GO:0016080)
0.0 0.1 GO:0006106 fumarate metabolic process(GO:0006106)
0.0 0.0 GO:0035987 endodermal cell fate commitment(GO:0001711) endodermal cell differentiation(GO:0035987)
0.0 0.2 GO:0055064 cellular chloride ion homeostasis(GO:0030644) chloride ion homeostasis(GO:0055064)
0.0 0.1 GO:0045085 negative regulation of interleukin-2 biosynthetic process(GO:0045085)
0.0 0.0 GO:0030889 negative regulation of B cell proliferation(GO:0030889)
0.0 0.0 GO:0010831 positive regulation of myotube differentiation(GO:0010831)
0.0 0.0 GO:0051152 positive regulation of smooth muscle cell differentiation(GO:0051152)
0.0 0.1 GO:0046940 nucleoside monophosphate phosphorylation(GO:0046940)
0.0 0.1 GO:0016103 diterpenoid catabolic process(GO:0016103) terpenoid catabolic process(GO:0016115) retinoic acid catabolic process(GO:0034653)
0.0 0.2 GO:0042362 fat-soluble vitamin biosynthetic process(GO:0042362)
0.0 0.0 GO:0044252 negative regulation of collagen metabolic process(GO:0010713) negative regulation of collagen biosynthetic process(GO:0032966) negative regulation of multicellular organismal metabolic process(GO:0044252)
0.0 0.2 GO:0002483 antigen processing and presentation of endogenous peptide antigen(GO:0002483) antigen processing and presentation of endogenous peptide antigen via MHC class I(GO:0019885)
0.0 0.1 GO:0035455 response to interferon-alpha(GO:0035455)
0.0 0.1 GO:0009048 dosage compensation by inactivation of X chromosome(GO:0009048)
0.0 0.7 GO:0035116 embryonic hindlimb morphogenesis(GO:0035116)
0.0 0.1 GO:0048387 negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.0 0.1 GO:0071392 cellular response to estradiol stimulus(GO:0071392)
0.0 0.1 GO:0006384 transcription initiation from RNA polymerase III promoter(GO:0006384)
0.0 0.2 GO:0030910 olfactory placode formation(GO:0030910) olfactory placode development(GO:0071698) olfactory placode morphogenesis(GO:0071699)
0.0 0.0 GO:0051608 histamine transport(GO:0051608)
0.0 0.2 GO:0046874 quinolinate metabolic process(GO:0046874)
0.0 0.1 GO:0070779 D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
0.0 0.3 GO:0030206 chondroitin sulfate biosynthetic process(GO:0030206)
0.0 0.0 GO:0071481 cellular response to X-ray(GO:0071481)
0.0 0.2 GO:0048096 chromatin-mediated maintenance of transcription(GO:0048096)
0.0 0.5 GO:0045576 mast cell activation(GO:0045576)
0.0 0.2 GO:2000258 negative regulation of complement activation(GO:0045916) negative regulation of protein activation cascade(GO:2000258)
0.0 0.0 GO:1901522 positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus(GO:1901522)
0.0 0.1 GO:0045722 positive regulation of gluconeogenesis(GO:0045722)
0.0 0.4 GO:0043508 negative regulation of JUN kinase activity(GO:0043508)
0.0 0.1 GO:0042726 flavin-containing compound metabolic process(GO:0042726)
0.0 0.4 GO:0045197 establishment or maintenance of epithelial cell apical/basal polarity(GO:0045197)
0.0 0.4 GO:0019059 obsolete initiation of viral infection(GO:0019059)
0.0 0.1 GO:0035092 sperm chromatin condensation(GO:0035092)
0.0 0.3 GO:0031146 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process(GO:0031146)
0.0 0.6 GO:0032012 regulation of ARF protein signal transduction(GO:0032012)
0.0 0.1 GO:0006154 adenosine catabolic process(GO:0006154)
0.0 0.3 GO:0006978 DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:0006978)
0.0 0.6 GO:0034199 activation of protein kinase A activity(GO:0034199)
0.0 0.4 GO:0050851 antigen receptor-mediated signaling pathway(GO:0050851)
0.0 0.2 GO:0045885 obsolete positive regulation of survival gene product expression(GO:0045885)
0.0 0.4 GO:0001954 positive regulation of cell-matrix adhesion(GO:0001954)
0.0 0.2 GO:0006030 chitin metabolic process(GO:0006030) chitin catabolic process(GO:0006032)
0.0 0.7 GO:0006691 leukotriene metabolic process(GO:0006691)
0.0 0.1 GO:0051461 corticotropin secretion(GO:0051458) regulation of corticotropin secretion(GO:0051459) positive regulation of corticotropin secretion(GO:0051461)
0.0 0.0 GO:0015014 heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.0 0.2 GO:0032875 regulation of DNA endoreduplication(GO:0032875) negative regulation of DNA endoreduplication(GO:0032876) DNA endoreduplication(GO:0042023)
0.0 0.1 GO:0035025 positive regulation of Rho protein signal transduction(GO:0035025)
0.0 0.1 GO:0007064 mitotic sister chromatid cohesion(GO:0007064)
0.0 0.1 GO:0019042 viral latency(GO:0019042)
0.0 0.1 GO:0009138 pyrimidine nucleoside diphosphate metabolic process(GO:0009138)
0.0 0.0 GO:0019372 lipoxygenase pathway(GO:0019372)
0.0 0.9 GO:0043484 regulation of RNA splicing(GO:0043484)
0.0 0.0 GO:0050765 negative regulation of phagocytosis(GO:0050765)
0.0 0.3 GO:0098927 early endosome to late endosome transport(GO:0045022) vesicle-mediated transport between endosomal compartments(GO:0098927)
0.0 0.1 GO:0019441 tryptophan catabolic process to kynurenine(GO:0019441)
0.0 0.1 GO:0043518 negative regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043518) negative regulation of signal transduction by p53 class mediator(GO:1901797)
0.0 0.1 GO:0045059 positive thymic T cell selection(GO:0045059)
0.0 0.3 GO:0006491 N-glycan processing(GO:0006491)
0.0 0.3 GO:0043029 T cell homeostasis(GO:0043029)
0.0 0.1 GO:0006104 succinyl-CoA metabolic process(GO:0006104)
0.0 0.1 GO:0006003 fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.0 0.2 GO:0045116 protein neddylation(GO:0045116)
0.0 0.7 GO:0006611 protein export from nucleus(GO:0006611)
0.0 0.0 GO:0045906 negative regulation of vasoconstriction(GO:0045906)
0.0 0.1 GO:0015816 glycine transport(GO:0015816)
0.0 0.4 GO:0045730 respiratory burst(GO:0045730)
0.0 0.2 GO:0048679 regulation of axon regeneration(GO:0048679) regulation of neuron projection regeneration(GO:0070570)
0.0 0.2 GO:0022614 membrane to membrane docking(GO:0022614)
0.0 0.3 GO:0002286 T cell activation involved in immune response(GO:0002286)
0.0 0.1 GO:0043619 regulation of transcription from RNA polymerase II promoter in response to oxidative stress(GO:0043619)
0.0 0.1 GO:0006422 aspartyl-tRNA aminoacylation(GO:0006422)
0.0 0.4 GO:0031648 protein destabilization(GO:0031648)
0.0 0.0 GO:0043570 maintenance of DNA repeat elements(GO:0043570)
0.0 0.0 GO:0051489 regulation of filopodium assembly(GO:0051489)
0.0 0.1 GO:0070837 dehydroascorbic acid transport(GO:0070837)
0.0 0.0 GO:0032785 negative regulation of DNA-templated transcription, elongation(GO:0032785) negative regulation of transcription elongation from RNA polymerase II promoter(GO:0034244)
0.0 0.1 GO:0006167 AMP biosynthetic process(GO:0006167)
0.0 0.1 GO:0046831 regulation of RNA export from nucleus(GO:0046831)
0.0 0.2 GO:0045717 negative regulation of fatty acid biosynthetic process(GO:0045717)
0.0 0.0 GO:0010979 regulation of vitamin D 24-hydroxylase activity(GO:0010979) positive regulation of vitamin D 24-hydroxylase activity(GO:0010980)
0.0 0.1 GO:0048711 positive regulation of astrocyte differentiation(GO:0048711)
0.0 0.2 GO:0050957 equilibrioception(GO:0050957)
0.0 0.1 GO:0006642 triglyceride mobilization(GO:0006642)
0.0 0.1 GO:0045824 negative regulation of innate immune response(GO:0045824)
0.0 0.1 GO:0045990 carbon catabolite regulation of transcription(GO:0045990) regulation of transcription by glucose(GO:0046015)
0.0 0.1 GO:0045006 DNA deamination(GO:0045006)
0.0 0.2 GO:0045910 negative regulation of DNA recombination(GO:0045910)
0.0 0.0 GO:0052555 positive regulation by organism of immune response of other organism involved in symbiotic interaction(GO:0052555) positive regulation by symbiont of host immune response(GO:0052556)
0.0 0.1 GO:0046877 regulation of saliva secretion(GO:0046877)
0.0 0.1 GO:0009106 lipoate metabolic process(GO:0009106)
0.0 0.0 GO:0033131 regulation of glucokinase activity(GO:0033131) positive regulation of glucokinase activity(GO:0033133) regulation of hexokinase activity(GO:1903299) positive regulation of hexokinase activity(GO:1903301)
0.0 0.1 GO:0006772 thiamine metabolic process(GO:0006772)
0.0 0.7 GO:0031294 lymphocyte costimulation(GO:0031294) T cell costimulation(GO:0031295)
0.0 0.0 GO:0060397 JAK-STAT cascade involved in growth hormone signaling pathway(GO:0060397)
0.0 0.1 GO:0070672 response to interleukin-15(GO:0070672)
0.0 0.1 GO:0017183 peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183)
0.0 0.1 GO:0050774 negative regulation of dendrite morphogenesis(GO:0050774)
0.0 0.2 GO:0030851 granulocyte differentiation(GO:0030851)
0.0 0.2 GO:0006621 protein retention in ER lumen(GO:0006621) maintenance of protein localization in endoplasmic reticulum(GO:0035437)
0.0 0.4 GO:0045646 regulation of erythrocyte differentiation(GO:0045646)
0.0 0.1 GO:0032506 cytokinetic process(GO:0032506)
0.0 0.0 GO:0090231 regulation of spindle checkpoint(GO:0090231)
0.0 0.0 GO:0052251 induction by organism of defense response of other organism involved in symbiotic interaction(GO:0052251)
0.0 0.1 GO:0033158 regulation of protein import into nucleus, translocation(GO:0033158)
0.0 0.1 GO:0006474 N-terminal protein amino acid acetylation(GO:0006474)
0.0 0.5 GO:0043124 negative regulation of I-kappaB kinase/NF-kappaB signaling(GO:0043124)
0.0 0.1 GO:0032328 alanine transport(GO:0032328)
0.0 0.1 GO:0052805 histidine catabolic process(GO:0006548) imidazole-containing compound catabolic process(GO:0052805)
0.0 0.2 GO:0045540 regulation of cholesterol biosynthetic process(GO:0045540)
0.0 0.1 GO:1901419 regulation of response to alcohol(GO:1901419)
0.0 0.1 GO:0045071 negative regulation of viral genome replication(GO:0045071)
0.0 0.1 GO:0040016 embryonic cleavage(GO:0040016)
0.0 0.1 GO:0051971 positive regulation of transmission of nerve impulse(GO:0051971)
0.0 0.1 GO:0007023 post-chaperonin tubulin folding pathway(GO:0007023)
0.0 0.0 GO:0034122 negative regulation of toll-like receptor signaling pathway(GO:0034122)
0.0 0.0 GO:0001973 adenosine receptor signaling pathway(GO:0001973) G-protein coupled purinergic receptor signaling pathway(GO:0035588)
0.0 0.2 GO:0016556 mRNA modification(GO:0016556)
0.0 0.0 GO:0032682 negative regulation of chemokine production(GO:0032682) negative regulation of chemokine biosynthetic process(GO:0045079)
0.0 0.0 GO:0048563 post-embryonic organ morphogenesis(GO:0048563)
0.0 0.3 GO:0071514 genetic imprinting(GO:0071514)
0.0 0.0 GO:0042789 mRNA transcription from RNA polymerase II promoter(GO:0042789)
0.0 0.2 GO:0006241 GTP biosynthetic process(GO:0006183) UTP biosynthetic process(GO:0006228) CTP biosynthetic process(GO:0006241) pyrimidine ribonucleoside triphosphate metabolic process(GO:0009208) pyrimidine ribonucleoside triphosphate biosynthetic process(GO:0009209) CTP metabolic process(GO:0046036) UTP metabolic process(GO:0046051)
0.0 0.0 GO:0002495 antigen processing and presentation of peptide antigen via MHC class II(GO:0002495)
0.0 0.0 GO:0008054 negative regulation of cyclin-dependent protein serine/threonine kinase by cyclin degradation(GO:0008054)
0.0 0.0 GO:0007262 STAT protein import into nucleus(GO:0007262)
0.0 0.1 GO:0006685 sphingomyelin catabolic process(GO:0006685)
0.0 0.1 GO:0051294 establishment of mitotic spindle orientation(GO:0000132) establishment of spindle orientation(GO:0051294)
0.0 0.1 GO:0010815 bradykinin catabolic process(GO:0010815)
0.0 0.1 GO:0008298 intracellular mRNA localization(GO:0008298)
0.0 0.1 GO:0017085 response to insecticide(GO:0017085)
0.0 0.1 GO:0042866 pyruvate biosynthetic process(GO:0042866)
0.0 0.1 GO:0003214 cardiac left ventricle morphogenesis(GO:0003214)
0.0 0.0 GO:2001012 mesenchymal cell differentiation involved in kidney development(GO:0072161) metanephric mesenchymal cell differentiation(GO:0072162) mesenchymal cell differentiation involved in renal system development(GO:2001012)
0.0 0.0 GO:0045292 mRNA cis splicing, via spliceosome(GO:0045292)
0.0 0.5 GO:0008630 intrinsic apoptotic signaling pathway in response to DNA damage(GO:0008630)
0.0 0.0 GO:2000399 negative regulation of T cell differentiation in thymus(GO:0033085) negative regulation of thymocyte aggregation(GO:2000399)
0.0 0.3 GO:0046834 lipid phosphorylation(GO:0046834)
0.0 0.1 GO:0032486 Rap protein signal transduction(GO:0032486)
0.0 0.1 GO:0034501 protein localization to kinetochore(GO:0034501)
0.0 1.5 GO:0006959 humoral immune response(GO:0006959)
0.0 0.0 GO:0032959 inositol trisphosphate biosynthetic process(GO:0032959)
0.0 0.3 GO:0060334 regulation of response to interferon-gamma(GO:0060330) regulation of interferon-gamma-mediated signaling pathway(GO:0060334)
0.0 0.2 GO:0050927 positive regulation of positive chemotaxis(GO:0050927)
0.0 0.1 GO:0006198 cAMP catabolic process(GO:0006198)
0.0 0.1 GO:0002076 osteoblast development(GO:0002076)
0.0 0.1 GO:0033522 histone H2A ubiquitination(GO:0033522)
0.0 0.0 GO:0071364 cellular response to epidermal growth factor stimulus(GO:0071364)
0.0 0.1 GO:0048714 positive regulation of oligodendrocyte differentiation(GO:0048714)
0.0 0.1 GO:0060219 camera-type eye photoreceptor cell differentiation(GO:0060219)
0.0 0.1 GO:0015791 polyol transport(GO:0015791)
0.0 0.1 GO:0006102 isocitrate metabolic process(GO:0006102)
0.0 0.0 GO:0002862 negative regulation of inflammatory response to antigenic stimulus(GO:0002862)
0.0 0.1 GO:0046835 carbohydrate phosphorylation(GO:0046835)
0.0 0.1 GO:0032988 ribonucleoprotein complex disassembly(GO:0032988)
0.0 0.0 GO:0019532 oxalate transport(GO:0019532)
0.0 0.1 GO:0051290 protein heterotetramerization(GO:0051290)
0.0 0.1 GO:0032715 negative regulation of interleukin-6 production(GO:0032715)
0.0 0.1 GO:0033687 osteoblast proliferation(GO:0033687)
0.0 0.1 GO:0006013 mannose metabolic process(GO:0006013)
0.0 0.1 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.0 0.0 GO:0061154 endothelial tube morphogenesis(GO:0061154)
0.0 0.1 GO:0031440 regulation of mRNA 3'-end processing(GO:0031440) positive regulation of mRNA 3'-end processing(GO:0031442) positive regulation of mRNA processing(GO:0050685) positive regulation of mRNA metabolic process(GO:1903313)
0.0 0.2 GO:0051568 histone H3-K4 methylation(GO:0051568)
0.0 0.0 GO:0002438 acute inflammatory response to antigenic stimulus(GO:0002438)
0.0 0.6 GO:0000245 spliceosomal complex assembly(GO:0000245)
0.0 0.0 GO:0045091 regulation of single stranded viral RNA replication via double stranded DNA intermediate(GO:0045091)
0.0 0.0 GO:0002230 positive regulation of defense response to virus by host(GO:0002230)
0.0 0.0 GO:0010642 negative regulation of platelet-derived growth factor receptor signaling pathway(GO:0010642)
0.0 0.1 GO:0070670 response to interleukin-4(GO:0070670)
0.0 0.1 GO:0007100 mitotic centrosome separation(GO:0007100)
0.0 0.0 GO:0010954 positive regulation of protein processing(GO:0010954) positive regulation of protein maturation(GO:1903319)
0.0 0.2 GO:0000085 mitotic G2 phase(GO:0000085) G2 phase(GO:0051319)
0.0 0.1 GO:0060023 soft palate development(GO:0060023)
0.0 0.2 GO:0030225 macrophage differentiation(GO:0030225)
0.0 0.3 GO:0042255 ribosome assembly(GO:0042255)
0.0 0.1 GO:0014051 gamma-aminobutyric acid secretion(GO:0014051)
0.0 0.0 GO:0042348 regulation of NF-kappaB import into nucleus(GO:0042345) NF-kappaB import into nucleus(GO:0042348)
0.0 0.2 GO:0042994 cytoplasmic sequestering of transcription factor(GO:0042994)
0.0 0.3 GO:0019724 B cell mediated immunity(GO:0019724)
0.0 0.1 GO:0046784 viral mRNA export from host cell nucleus(GO:0046784)
0.0 0.0 GO:0034447 very-low-density lipoprotein particle clearance(GO:0034447)
0.0 0.2 GO:0006895 Golgi to endosome transport(GO:0006895) Golgi to vacuole transport(GO:0006896)
0.0 0.1 GO:0030186 melatonin metabolic process(GO:0030186) melatonin biosynthetic process(GO:0030187)
0.0 0.1 GO:0010792 DNA double-strand break processing involved in repair via single-strand annealing(GO:0010792) double-strand break repair via single-strand annealing(GO:0045002)
0.0 0.1 GO:0034372 triglyceride-rich lipoprotein particle remodeling(GO:0034370) very-low-density lipoprotein particle remodeling(GO:0034372)
0.0 0.1 GO:0060760 positive regulation of response to cytokine stimulus(GO:0060760)
0.0 0.1 GO:1900087 traversing start control point of mitotic cell cycle(GO:0007089) positive regulation of G1/S transition of mitotic cell cycle(GO:1900087) positive regulation of cell cycle G1/S phase transition(GO:1902808)
0.0 0.2 GO:0090630 activation of GTPase activity(GO:0090630)
0.0 0.0 GO:0014874 response to stimulus involved in regulation of muscle adaptation(GO:0014874)
0.0 0.1 GO:0001945 lymph vessel development(GO:0001945)
0.0 0.3 GO:0016601 Rac protein signal transduction(GO:0016601)
0.0 0.1 GO:0000089 mitotic metaphase(GO:0000089)
0.0 0.1 GO:0000012 single strand break repair(GO:0000012)
0.0 0.1 GO:0006264 mitochondrial DNA replication(GO:0006264)
0.0 0.1 GO:0032525 somite rostral/caudal axis specification(GO:0032525)
0.0 0.1 GO:0035335 peptidyl-tyrosine dephosphorylation(GO:0035335)
0.0 0.1 GO:0000103 sulfate assimilation(GO:0000103)
0.0 0.3 GO:0019933 cAMP-mediated signaling(GO:0019933)
0.0 0.1 GO:0031115 negative regulation of microtubule polymerization(GO:0031115)
0.0 0.5 GO:0050772 positive regulation of axonogenesis(GO:0050772)
0.0 0.2 GO:0051353 positive regulation of oxidoreductase activity(GO:0051353)
0.0 0.2 GO:0015693 magnesium ion transport(GO:0015693)
0.0 0.0 GO:0032494 response to peptidoglycan(GO:0032494)
0.0 0.2 GO:0007032 endosome organization(GO:0007032)
0.0 0.1 GO:0010739 positive regulation of protein kinase A signaling(GO:0010739)
0.0 0.1 GO:0006546 glycine catabolic process(GO:0006546)
0.0 0.1 GO:0015074 DNA integration(GO:0015074)
0.0 0.1 GO:0042816 pyridoxine metabolic process(GO:0008614) pyridoxine biosynthetic process(GO:0008615) vitamin B6 metabolic process(GO:0042816) vitamin B6 biosynthetic process(GO:0042819)
0.0 0.2 GO:0007379 segment specification(GO:0007379)
0.0 0.0 GO:0042226 interleukin-6 biosynthetic process(GO:0042226)
0.0 0.0 GO:0048539 bone marrow development(GO:0048539)
0.0 0.1 GO:0050691 regulation of defense response to virus by host(GO:0050691)
0.0 0.0 GO:0033504 floor plate development(GO:0033504)
0.0 0.1 GO:0072583 synaptic vesicle recycling(GO:0036465) synaptic vesicle endocytosis(GO:0048488) clathrin-mediated endocytosis(GO:0072583)
0.0 0.0 GO:0040001 establishment of mitotic spindle localization(GO:0040001)
0.0 0.0 GO:0045347 negative regulation of MHC class II biosynthetic process(GO:0045347)
0.0 0.0 GO:0045603 positive regulation of endothelial cell differentiation(GO:0045603)
0.0 0.0 GO:0042130 negative regulation of T cell proliferation(GO:0042130)
0.0 0.1 GO:0006020 inositol metabolic process(GO:0006020)
0.0 0.1 GO:0007090 obsolete regulation of S phase of mitotic cell cycle(GO:0007090)
0.0 0.0 GO:0045618 positive regulation of keratinocyte differentiation(GO:0045618)
0.0 0.0 GO:0075733 multi-organism transport(GO:0044766) transport of virus(GO:0046794) intracellular transport of virus(GO:0075733) multi-organism localization(GO:1902579) multi-organism intracellular transport(GO:1902583)
0.0 0.0 GO:2000114 regulation of establishment of cell polarity(GO:2000114)
0.0 0.1 GO:0050775 positive regulation of dendrite morphogenesis(GO:0050775) positive regulation of dendrite development(GO:1900006)
0.0 0.0 GO:0046968 peptide antigen transport(GO:0046968)
0.0 0.0 GO:0043983 histone H4-K12 acetylation(GO:0043983)
0.0 0.0 GO:0002085 inhibition of neuroepithelial cell differentiation(GO:0002085)
0.0 0.1 GO:0050910 detection of mechanical stimulus involved in sensory perception of sound(GO:0050910)
0.0 0.1 GO:0031427 response to methotrexate(GO:0031427)
0.0 0.0 GO:0031646 positive regulation of neurological system process(GO:0031646)
0.0 0.1 GO:0006570 tyrosine metabolic process(GO:0006570)
0.0 0.1 GO:0001573 ganglioside metabolic process(GO:0001573)
0.0 0.0 GO:0016572 histone phosphorylation(GO:0016572)
0.0 0.2 GO:0006379 mRNA cleavage(GO:0006379)
0.0 0.1 GO:0046697 decidualization(GO:0046697)
0.0 0.0 GO:0043457 regulation of cellular respiration(GO:0043457)
0.0 0.0 GO:0018125 peptidyl-cysteine methylation(GO:0018125)
0.0 0.1 GO:0046689 response to mercury ion(GO:0046689)
0.0 0.0 GO:0045084 positive regulation of interleukin-12 biosynthetic process(GO:0045084)
0.0 0.0 GO:0060676 ureteric bud formation(GO:0060676)
0.0 0.0 GO:0000462 endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000447) maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000462) cleavage involved in rRNA processing(GO:0000469) endonucleolytic cleavage involved in rRNA processing(GO:0000478) endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000479) maturation of SSU-rRNA(GO:0030490) RNA phosphodiester bond hydrolysis, endonucleolytic(GO:0090502)
0.0 0.1 GO:0040020 regulation of meiotic nuclear division(GO:0040020)
0.0 0.1 GO:0045351 type I interferon biosynthetic process(GO:0045351)
0.0 0.1 GO:0009804 phenylpropanoid metabolic process(GO:0009698) coumarin metabolic process(GO:0009804)
0.0 0.0 GO:0019605 butyrate metabolic process(GO:0019605)
0.0 0.1 GO:0007191 adenylate cyclase-activating dopamine receptor signaling pathway(GO:0007191)
0.0 0.0 GO:0010457 centriole-centriole cohesion(GO:0010457)
0.0 0.0 GO:0003077 obsolete negative regulation of diuresis(GO:0003077)
0.0 0.4 GO:0060333 interferon-gamma-mediated signaling pathway(GO:0060333)
0.0 0.4 GO:0003333 amino acid transmembrane transport(GO:0003333)
0.0 0.1 GO:0042359 vitamin D metabolic process(GO:0042359)
0.0 0.0 GO:0033632 regulation of cell-cell adhesion mediated by integrin(GO:0033632)
0.0 1.0 GO:0000216 obsolete M/G1 transition of mitotic cell cycle(GO:0000216)
0.0 0.1 GO:0009649 entrainment of circadian clock(GO:0009649)
0.0 0.4 GO:0021549 cerebellum development(GO:0021549)
0.0 0.1 GO:0006516 glycoprotein catabolic process(GO:0006516)
0.0 0.1 GO:0000076 DNA replication checkpoint(GO:0000076)
0.0 0.1 GO:0000038 very long-chain fatty acid metabolic process(GO:0000038)
0.0 0.2 GO:0016578 histone deubiquitination(GO:0016578)
0.0 0.0 GO:0035511 oxidative DNA demethylation(GO:0035511)
0.0 0.0 GO:0071549 cellular response to dexamethasone stimulus(GO:0071549)
0.0 0.0 GO:0060596 mammary placode formation(GO:0060596)
0.0 0.0 GO:0006011 UDP-glucose metabolic process(GO:0006011)
0.0 0.4 GO:0016579 protein deubiquitination(GO:0016579)
0.0 0.1 GO:0045746 negative regulation of Notch signaling pathway(GO:0045746)
0.0 0.1 GO:0016098 monoterpenoid metabolic process(GO:0016098)
0.0 0.0 GO:0030174 regulation of DNA-dependent DNA replication initiation(GO:0030174)
0.0 0.1 GO:0032008 positive regulation of TOR signaling(GO:0032008)
0.0 0.1 GO:0034341 response to interferon-gamma(GO:0034341)
0.0 0.0 GO:0044818 mitotic G2 DNA damage checkpoint(GO:0007095) mitotic G2/M transition checkpoint(GO:0044818)
0.0 0.3 GO:0000289 nuclear-transcribed mRNA poly(A) tail shortening(GO:0000289)
0.0 0.2 GO:0016254 preassembly of GPI anchor in ER membrane(GO:0016254)
0.0 0.0 GO:0072393 microtubule anchoring at microtubule organizing center(GO:0072393)
0.0 0.2 GO:0043967 histone H4 acetylation(GO:0043967)
0.0 0.1 GO:0009051 pentose-phosphate shunt, oxidative branch(GO:0009051)
0.0 0.0 GO:0045988 negative regulation of striated muscle contraction(GO:0045988)
0.0 0.1 GO:0045109 intermediate filament organization(GO:0045109)
0.0 0.0 GO:0009301 snRNA transcription(GO:0009301)
0.0 0.1 GO:0033523 histone H2B ubiquitination(GO:0033523)
0.0 0.0 GO:0046688 response to copper ion(GO:0046688)
0.0 0.1 GO:0046415 urate metabolic process(GO:0046415)
0.0 0.6 GO:0007498 mesoderm development(GO:0007498)
0.0 0.1 GO:0045987 positive regulation of smooth muscle contraction(GO:0045987)
0.0 0.1 GO:0050962 detection of light stimulus involved in visual perception(GO:0050908) detection of light stimulus involved in sensory perception(GO:0050962)
0.0 0.1 GO:0010669 epithelial structure maintenance(GO:0010669) maintenance of gastrointestinal epithelium(GO:0030277)
0.0 0.0 GO:0060586 multicellular organismal iron ion homeostasis(GO:0060586)
0.0 0.0 GO:0060766 negative regulation of androgen receptor signaling pathway(GO:0060766)
0.0 0.0 GO:0042772 DNA damage response, signal transduction resulting in transcription(GO:0042772)
0.0 0.0 GO:0032878 regulation of establishment or maintenance of cell polarity(GO:0032878)
0.0 0.0 GO:0060157 urinary bladder development(GO:0060157)
0.0 0.1 GO:0043628 ncRNA 3'-end processing(GO:0043628)
0.0 0.0 GO:0016576 histone dephosphorylation(GO:0016576)
0.0 0.0 GO:0032042 mitochondrial DNA metabolic process(GO:0032042)
0.0 0.1 GO:0000183 chromatin silencing at rDNA(GO:0000183)
0.0 0.2 GO:0080171 lysosome organization(GO:0007040) lytic vacuole organization(GO:0080171)
0.0 0.0 GO:0034145 regulation of toll-like receptor 4 signaling pathway(GO:0034143) positive regulation of toll-like receptor 4 signaling pathway(GO:0034145)
0.0 0.0 GO:1903726 negative regulation of phospholipid metabolic process(GO:1903726)
0.0 0.0 GO:0019388 galactose catabolic process(GO:0019388)
0.0 0.1 GO:0032000 positive regulation of fatty acid beta-oxidation(GO:0032000)
0.0 0.2 GO:0042776 mitochondrial ATP synthesis coupled proton transport(GO:0042776)
0.0 0.0 GO:0010832 negative regulation of myotube differentiation(GO:0010832)
0.0 0.0 GO:0048570 notochord morphogenesis(GO:0048570)
0.0 0.0 GO:0015851 nucleobase transport(GO:0015851)
0.0 0.0 GO:0010107 potassium ion import(GO:0010107)
0.0 0.1 GO:0042219 cellular modified amino acid catabolic process(GO:0042219)
0.0 0.1 GO:0008635 activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c(GO:0008635)
0.0 0.0 GO:0051103 DNA ligation involved in DNA repair(GO:0051103)
0.0 0.0 GO:0000019 regulation of mitotic recombination(GO:0000019)
0.0 0.0 GO:0010737 protein kinase A signaling(GO:0010737) regulation of protein kinase A signaling(GO:0010738)
0.0 0.0 GO:0000380 alternative mRNA splicing, via spliceosome(GO:0000380)
0.0 0.1 GO:0043252 sodium-independent organic anion transport(GO:0043252)
0.0 0.0 GO:0021542 dentate gyrus development(GO:0021542)
0.0 0.2 GO:0033209 tumor necrosis factor-mediated signaling pathway(GO:0033209)
0.0 0.1 GO:0015813 L-glutamate transport(GO:0015813)
0.0 0.0 GO:0032604 granulocyte macrophage colony-stimulating factor production(GO:0032604) regulation of granulocyte macrophage colony-stimulating factor production(GO:0032645)
0.0 0.0 GO:0034121 regulation of toll-like receptor signaling pathway(GO:0034121)
0.0 0.2 GO:0030968 endoplasmic reticulum unfolded protein response(GO:0030968) cellular response to unfolded protein(GO:0034620)
0.0 0.1 GO:0009129 pyrimidine nucleoside monophosphate metabolic process(GO:0009129)
0.0 0.0 GO:0006391 transcription initiation from mitochondrial promoter(GO:0006391)
0.0 0.1 GO:0032755 positive regulation of interleukin-6 production(GO:0032755)
0.0 0.2 GO:0051351 positive regulation of ligase activity(GO:0051351)
0.0 0.1 GO:0003009 skeletal muscle contraction(GO:0003009)
0.0 0.1 GO:0006072 glycerol-3-phosphate metabolic process(GO:0006072)
0.0 0.0 GO:0070265 necrotic cell death(GO:0070265)
0.0 0.2 GO:0001938 positive regulation of endothelial cell proliferation(GO:0001938)
0.0 0.1 GO:0034314 Arp2/3 complex-mediated actin nucleation(GO:0034314)
0.0 0.0 GO:0006824 cobalt ion transport(GO:0006824)
0.0 0.0 GO:0045943 positive regulation of transcription from RNA polymerase I promoter(GO:0045943)
0.0 0.3 GO:0006635 fatty acid beta-oxidation(GO:0006635)
0.0 0.0 GO:0016557 peroxisome membrane biogenesis(GO:0016557)
0.0 0.0 GO:2000831 corticosteroid hormone secretion(GO:0035930) regulation of steroid hormone secretion(GO:2000831) regulation of corticosteroid hormone secretion(GO:2000846)
0.0 0.1 GO:0034033 nucleoside bisphosphate biosynthetic process(GO:0033866) ribonucleoside bisphosphate biosynthetic process(GO:0034030) purine nucleoside bisphosphate biosynthetic process(GO:0034033)
0.0 0.0 GO:0043653 mitochondrial fragmentation involved in apoptotic process(GO:0043653)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)
0.1 0.3 GO:0000942 condensed nuclear chromosome outer kinetochore(GO:0000942)
0.1 0.2 GO:0072487 MSL complex(GO:0072487)
0.1 0.2 GO:0070022 transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.1 0.4 GO:0045179 apical cortex(GO:0045179)
0.1 0.5 GO:0042589 zymogen granule membrane(GO:0042589)
0.1 0.4 GO:0044224 juxtaparanode region of axon(GO:0044224)
0.1 0.1 GO:0031931 TORC1 complex(GO:0031931)
0.1 0.5 GO:0042598 obsolete vesicular fraction(GO:0042598)
0.1 0.2 GO:0045323 interleukin-1 receptor complex(GO:0045323)
0.1 0.3 GO:0005797 Golgi medial cisterna(GO:0005797)
0.1 0.8 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.1 0.4 GO:0001891 phagocytic cup(GO:0001891)
0.1 0.5 GO:0001772 immunological synapse(GO:0001772)
0.1 0.5 GO:0034518 mRNA cap binding complex(GO:0005845) RNA cap binding complex(GO:0034518)
0.1 0.2 GO:0044462 external encapsulating structure part(GO:0044462)
0.1 0.2 GO:0042583 chromaffin granule(GO:0042583) chromaffin granule membrane(GO:0042584)
0.0 0.2 GO:0033256 I-kappaB/NF-kappaB complex(GO:0033256)
0.0 0.2 GO:0070695 FHF complex(GO:0070695)
0.0 0.4 GO:0000808 origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.0 0.4 GO:0045239 tricarboxylic acid cycle enzyme complex(GO:0045239)
0.0 0.3 GO:0070688 MLL5-L complex(GO:0070688)
0.0 0.1 GO:0001940 male pronucleus(GO:0001940)
0.0 0.3 GO:0043190 ATP-binding cassette (ABC) transporter complex(GO:0043190)
0.0 0.3 GO:0016461 unconventional myosin complex(GO:0016461)
0.0 0.1 GO:0005896 interleukin-6 receptor complex(GO:0005896)
0.0 0.2 GO:0019907 cyclin-dependent protein kinase activating kinase holoenzyme complex(GO:0019907)
0.0 0.2 GO:0005639 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229) nuclear membrane part(GO:0044453)
0.0 0.3 GO:0042101 T cell receptor complex(GO:0042101)
0.0 0.4 GO:0008180 COP9 signalosome(GO:0008180)
0.0 0.1 GO:0000137 Golgi cis cisterna(GO:0000137)
0.0 0.1 GO:0009331 glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.0 0.2 GO:0031254 uropod(GO:0001931) cell trailing edge(GO:0031254)
0.0 0.2 GO:0031264 death-inducing signaling complex(GO:0031264)
0.0 0.4 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.0 0.1 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.0 0.1 GO:0071438 invadopodium membrane(GO:0071438)
0.0 0.4 GO:0031672 A band(GO:0031672)
0.0 0.2 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
0.0 0.2 GO:0042582 primary lysosome(GO:0005766) azurophil granule(GO:0042582)
0.0 0.2 GO:0048786 presynaptic active zone(GO:0048786)
0.0 0.2 GO:0034451 centriolar satellite(GO:0034451)
0.0 0.1 GO:0043218 compact myelin(GO:0043218)
0.0 0.1 GO:0033150 cytoskeletal calyx(GO:0033150)
0.0 0.1 GO:0030934 anchoring collagen complex(GO:0030934)
0.0 0.3 GO:0043209 myelin sheath(GO:0043209)
0.0 0.4 GO:0016514 SWI/SNF complex(GO:0016514)
0.0 0.3 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.0 0.3 GO:0005838 proteasome regulatory particle(GO:0005838)
0.0 0.2 GO:0043020 NADPH oxidase complex(GO:0043020)
0.0 0.3 GO:0034362 low-density lipoprotein particle(GO:0034362)
0.0 0.3 GO:0031519 PcG protein complex(GO:0031519)
0.0 0.0 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.0 0.2 GO:0030893 meiotic cohesin complex(GO:0030893)
0.0 0.2 GO:0098984 asymmetric synapse(GO:0032279) neuron to neuron synapse(GO:0098984)
0.0 0.1 GO:0001652 granular component(GO:0001652)
0.0 0.3 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.0 0.1 GO:0044298 neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.0 0.5 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)
0.0 0.1 GO:0005862 muscle thin filament tropomyosin(GO:0005862)
0.0 1.0 GO:0035097 methyltransferase complex(GO:0034708) histone methyltransferase complex(GO:0035097)
0.0 1.0 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.0 0.1 GO:0031616 spindle pole centrosome(GO:0031616)
0.0 0.3 GO:0071203 WASH complex(GO:0071203)
0.0 0.1 GO:0031095 platelet dense tubular network membrane(GO:0031095)
0.0 0.1 GO:0000300 obsolete peripheral to membrane of membrane fraction(GO:0000300)
0.0 0.0 GO:0000800 lateral element(GO:0000800)
0.0 0.3 GO:0016235 aggresome(GO:0016235)
0.0 0.2 GO:0032040 small-subunit processome(GO:0032040)
0.0 0.1 GO:0000444 MIS12/MIND type complex(GO:0000444)
0.0 0.4 GO:0005763 organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.0 0.1 GO:0033553 rDNA heterochromatin(GO:0033553)
0.0 0.2 GO:0033162 melanosome membrane(GO:0033162) chitosome(GO:0045009)
0.0 0.2 GO:0005775 vacuolar lumen(GO:0005775)
0.0 1.0 GO:0016605 PML body(GO:0016605)
0.0 0.1 GO:0005850 eukaryotic translation initiation factor 2 complex(GO:0005850)
0.0 0.1 GO:0001741 XY body(GO:0001741)
0.0 0.1 GO:0030670 phagocytic vesicle membrane(GO:0030670)
0.0 0.1 GO:0042788 polysomal ribosome(GO:0042788)
0.0 0.1 GO:0032839 dendrite cytoplasm(GO:0032839)
0.0 0.1 GO:0030895 apolipoprotein B mRNA editing enzyme complex(GO:0030895)
0.0 0.1 GO:0030673 axolemma(GO:0030673)
0.0 0.1 GO:0030904 retromer complex(GO:0030904)
0.0 0.2 GO:0005844 polysome(GO:0005844)
0.0 0.1 GO:0000346 transcription export complex(GO:0000346)
0.0 0.1 GO:0005742 mitochondrial outer membrane translocase complex(GO:0005742)
0.0 0.0 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.0 0.2 GO:0090568 NuRD complex(GO:0016581) CHD-type complex(GO:0090545) nuclear transcriptional repressor complex(GO:0090568)
0.0 2.1 GO:0009897 external side of plasma membrane(GO:0009897)
0.0 0.0 GO:0032009 early phagosome(GO:0032009)
0.0 0.3 GO:0030864 cortical actin cytoskeleton(GO:0030864)
0.0 0.1 GO:0005869 dynactin complex(GO:0005869)
0.0 0.0 GO:0071256 Sec61 translocon complex(GO:0005784) translocon complex(GO:0071256)
0.0 0.2 GO:0005669 transcription factor TFIID complex(GO:0005669)
0.0 0.0 GO:0034363 intermediate-density lipoprotein particle(GO:0034363)
0.0 0.0 GO:0070820 tertiary granule(GO:0070820)
0.0 0.2 GO:0005720 nuclear heterochromatin(GO:0005720)
0.0 0.1 GO:0070552 BRISC complex(GO:0070552)
0.0 0.1 GO:0032590 dendrite membrane(GO:0032590)
0.0 0.0 GO:0070062 extracellular exosome(GO:0070062) extracellular vesicle(GO:1903561)
0.0 0.0 GO:0033011 perinuclear theca(GO:0033011)
0.0 0.0 GO:0010369 chromocenter(GO:0010369)
0.0 0.2 GO:0030130 clathrin coat of trans-Golgi network vesicle(GO:0030130)
0.0 0.0 GO:0008282 ATP-sensitive potassium channel complex(GO:0008282)
0.0 0.1 GO:0048500 signal recognition particle, endoplasmic reticulum targeting(GO:0005786) signal recognition particle(GO:0048500)
0.0 0.1 GO:0042627 chylomicron(GO:0042627)
0.0 0.8 GO:0000502 proteasome complex(GO:0000502)
0.0 0.1 GO:0005678 obsolete chromatin assembly complex(GO:0005678)
0.0 0.1 GO:0042555 MCM complex(GO:0042555)
0.0 1.7 GO:0005769 early endosome(GO:0005769)
0.0 0.1 GO:0005683 U7 snRNP(GO:0005683)
0.0 0.3 GO:0005680 anaphase-promoting complex(GO:0005680)
0.0 0.1 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.0 0.0 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.0 0.0 GO:0030688 preribosome, small subunit precursor(GO:0030688)
0.0 0.1 GO:0016272 prefoldin complex(GO:0016272)
0.0 0.2 GO:1990777 protein-lipid complex(GO:0032994) plasma lipoprotein particle(GO:0034358) lipoprotein particle(GO:1990777)
0.0 0.1 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.0 0.0 GO:0005954 calcium- and calmodulin-dependent protein kinase complex(GO:0005954)
0.0 0.0 GO:0031465 Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
0.0 0.1 GO:0031231 integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231)
0.0 0.0 GO:0002080 acrosomal membrane(GO:0002080)
0.0 0.1 GO:0035631 CD40 receptor complex(GO:0035631)
0.0 0.1 GO:0005861 troponin complex(GO:0005861)
0.0 0.1 GO:0016234 inclusion body(GO:0016234)
0.0 0.1 GO:0030127 COPII vesicle coat(GO:0030127)
0.0 0.1 GO:0000153 cytoplasmic ubiquitin ligase complex(GO:0000153)
0.0 0.0 GO:0042825 TAP complex(GO:0042825)
0.0 0.4 GO:0005876 spindle microtubule(GO:0005876)
0.0 0.0 GO:0017071 intracellular cyclic nucleotide activated cation channel complex(GO:0017071)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.6 GO:0004911 interleukin-2 receptor activity(GO:0004911)
0.2 0.5 GO:0004517 nitric-oxide synthase activity(GO:0004517)
0.1 0.4 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.1 0.4 GO:0016309 1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
0.1 1.9 GO:0004697 protein kinase C activity(GO:0004697)
0.1 1.3 GO:0016493 C-C chemokine receptor activity(GO:0016493)
0.1 0.6 GO:0046934 phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) phosphatidylinositol bisphosphate kinase activity(GO:0052813)
0.1 0.9 GO:0015271 outward rectifier potassium channel activity(GO:0015271)
0.1 0.6 GO:0004563 beta-N-acetylhexosaminidase activity(GO:0004563)
0.1 0.4 GO:0004528 phosphodiesterase I activity(GO:0004528)
0.1 0.5 GO:0030955 potassium ion binding(GO:0030955)
0.1 0.3 GO:0003726 double-stranded RNA adenosine deaminase activity(GO:0003726)
0.1 0.6 GO:0016494 C-X-C chemokine receptor activity(GO:0016494)
0.1 0.1 GO:0001098 basal transcription machinery binding(GO:0001098) basal RNA polymerase II transcription machinery binding(GO:0001099)
0.1 1.0 GO:0016888 endodeoxyribonuclease activity, producing 5'-phosphomonoesters(GO:0016888)
0.1 0.2 GO:0047756 chondroitin 4-sulfotransferase activity(GO:0047756)
0.1 0.3 GO:0004583 dolichyl-phosphate-glucose-glycolipid alpha-glucosyltransferase activity(GO:0004583)
0.1 0.1 GO:0019959 C-X-C chemokine binding(GO:0019958) interleukin-8 binding(GO:0019959)
0.1 0.2 GO:0008545 JUN kinase kinase activity(GO:0008545)
0.1 0.2 GO:0004465 lipoprotein lipase activity(GO:0004465)
0.1 0.2 GO:0016842 amidine-lyase activity(GO:0016842)
0.1 0.2 GO:0004476 mannose-6-phosphate isomerase activity(GO:0004476)
0.1 0.5 GO:0003688 DNA replication origin binding(GO:0003688)
0.1 0.5 GO:0004955 prostaglandin receptor activity(GO:0004955)
0.1 0.3 GO:0030284 estrogen receptor activity(GO:0030284)
0.1 0.5 GO:0050700 CARD domain binding(GO:0050700)
0.1 0.7 GO:0004859 phospholipase inhibitor activity(GO:0004859)
0.1 0.2 GO:0046923 ER retention sequence binding(GO:0046923)
0.1 0.2 GO:0030368 interleukin-17 receptor activity(GO:0030368)
0.1 0.1 GO:0070215 obsolete MDM2 binding(GO:0070215)
0.1 0.3 GO:0005131 growth hormone receptor binding(GO:0005131)
0.1 0.2 GO:0015562 efflux transmembrane transporter activity(GO:0015562)
0.1 0.2 GO:0033691 sialic acid binding(GO:0033691)
0.1 0.8 GO:0005095 GTPase inhibitor activity(GO:0005095)
0.1 0.2 GO:0030899 calcium-dependent ATPase activity(GO:0030899)
0.1 0.3 GO:0016907 G-protein coupled acetylcholine receptor activity(GO:0016907)
0.1 0.3 GO:0004904 interferon receptor activity(GO:0004904)
0.1 0.2 GO:0015925 galactosidase activity(GO:0015925)
0.1 0.2 GO:0004083 bisphosphoglycerate mutase activity(GO:0004082) bisphosphoglycerate 2-phosphatase activity(GO:0004083) phosphoglycerate mutase activity(GO:0004619)
0.1 0.5 GO:0046527 glucosyltransferase activity(GO:0046527)
0.1 0.2 GO:0001758 retinal dehydrogenase activity(GO:0001758)
0.1 0.2 GO:0015379 potassium:chloride symporter activity(GO:0015379)
0.1 1.3 GO:0001608 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.1 1.9 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.1 0.1 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
0.1 0.3 GO:0061133 endopeptidase activator activity(GO:0061133)
0.1 0.3 GO:0016308 1-phosphatidylinositol-4-phosphate 5-kinase activity(GO:0016308)
0.1 0.3 GO:0005381 iron ion transmembrane transporter activity(GO:0005381)
0.1 0.2 GO:0016509 long-chain-3-hydroxyacyl-CoA dehydrogenase activity(GO:0016509)
0.1 0.2 GO:0004719 protein-L-isoaspartate (D-aspartate) O-methyltransferase activity(GO:0004719)
0.1 0.5 GO:0048531 beta-1,3-galactosyltransferase activity(GO:0048531)
0.1 0.1 GO:0016312 inositol bisphosphate phosphatase activity(GO:0016312)
0.1 0.2 GO:0004607 phosphatidylcholine-sterol O-acyltransferase activity(GO:0004607)
0.1 0.1 GO:0010340 carboxyl-O-methyltransferase activity(GO:0010340) protein carboxyl O-methyltransferase activity(GO:0051998)
0.0 0.1 GO:0030375 thyroid hormone receptor coactivator activity(GO:0030375)
0.0 0.3 GO:0070087 chromo shadow domain binding(GO:0070087)
0.0 0.2 GO:0047238 glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity(GO:0047238)
0.0 0.1 GO:0043141 ATP-dependent 5'-3' DNA helicase activity(GO:0043141)
0.0 0.1 GO:0042608 T cell receptor binding(GO:0042608)
0.0 0.1 GO:0016728 ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
0.0 0.1 GO:0003836 beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.0 0.2 GO:0004974 leukotriene receptor activity(GO:0004974)
0.0 0.2 GO:0008266 poly(U) RNA binding(GO:0008266)
0.0 0.1 GO:0008474 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.0 0.5 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.0 0.1 GO:0042392 sphingosine-1-phosphate phosphatase activity(GO:0042392)
0.0 0.3 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.0 0.1 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.0 2.1 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.0 0.1 GO:0004966 galanin receptor activity(GO:0004966)
0.0 1.0 GO:0004177 aminopeptidase activity(GO:0004177)
0.0 0.1 GO:0052658 inositol-1,4,5-trisphosphate 5-phosphatase activity(GO:0052658) inositol-1,3,4,5-tetrakisphosphate 5-phosphatase activity(GO:0052659)
0.0 0.2 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.0 0.1 GO:0003910 DNA ligase activity(GO:0003909) DNA ligase (ATP) activity(GO:0003910)
0.0 0.3 GO:0004568 chitinase activity(GO:0004568)
0.0 0.1 GO:0031628 opioid receptor binding(GO:0031628)
0.0 0.1 GO:0004886 9-cis retinoic acid receptor activity(GO:0004886)
0.0 0.2 GO:0034452 dynactin binding(GO:0034452)
0.0 0.6 GO:0008373 sialyltransferase activity(GO:0008373)
0.0 0.1 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.0 0.2 GO:0070513 death domain binding(GO:0070513)
0.0 0.1 GO:0055103 ligase regulator activity(GO:0055103) ubiquitin-protein transferase regulator activity(GO:0055106)
0.0 0.1 GO:0000739 obsolete DNA strand annealing activity(GO:0000739)
0.0 0.3 GO:0005114 type II transforming growth factor beta receptor binding(GO:0005114)
0.0 0.1 GO:0004873 asialoglycoprotein receptor activity(GO:0004873)
0.0 0.0 GO:0035197 siRNA binding(GO:0035197)
0.0 0.1 GO:0004367 glycerol-3-phosphate dehydrogenase [NAD+] activity(GO:0004367)
0.0 0.4 GO:0031078 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041) histone deacetylase activity (H4-K16 specific)(GO:0034739) NAD-dependent histone deacetylase activity (H4-K16 specific)(GO:0046970)
0.0 0.1 GO:0008131 primary amine oxidase activity(GO:0008131)
0.0 0.1 GO:0019788 NEDD8 transferase activity(GO:0019788)
0.0 0.1 GO:0035252 UDP-xylosyltransferase activity(GO:0035252) xylosyltransferase activity(GO:0042285)
0.0 0.1 GO:0031685 adenosine receptor binding(GO:0031685)
0.0 0.6 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0 0.2 GO:0000339 RNA cap binding(GO:0000339)
0.0 0.1 GO:0004949 cannabinoid receptor activity(GO:0004949)
0.0 0.2 GO:0016502 purinergic nucleotide receptor activity(GO:0001614) nucleotide receptor activity(GO:0016502)
0.0 0.5 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.0 0.4 GO:0004016 adenylate cyclase activity(GO:0004016)
0.0 0.1 GO:0005220 inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.0 0.1 GO:0004045 aminoacyl-tRNA hydrolase activity(GO:0004045)
0.0 0.1 GO:0008401 retinoic acid 4-hydroxylase activity(GO:0008401)
0.0 0.2 GO:0001784 phosphotyrosine binding(GO:0001784)
0.0 0.1 GO:0031957 very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.0 0.9 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.0 0.2 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.0 0.1 GO:0043024 ribosomal small subunit binding(GO:0043024)
0.0 0.1 GO:0042799 histone methyltransferase activity (H4-K20 specific)(GO:0042799)
0.0 0.1 GO:0030346 protein phosphatase 2B binding(GO:0030346)
0.0 0.2 GO:0016841 ammonia-lyase activity(GO:0016841)
0.0 0.1 GO:0045159 myosin II binding(GO:0045159)
0.0 0.2 GO:0004704 NF-kappaB-inducing kinase activity(GO:0004704)
0.0 0.1 GO:0004449 isocitrate dehydrogenase (NAD+) activity(GO:0004449)
0.0 0.6 GO:0043621 protein self-association(GO:0043621)
0.0 0.3 GO:0004579 oligosaccharyl transferase activity(GO:0004576) dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.0 0.1 GO:0071723 lipopeptide binding(GO:0071723)
0.0 0.1 GO:0004815 aspartate-tRNA ligase activity(GO:0004815)
0.0 0.2 GO:0004983 neuropeptide Y receptor activity(GO:0004983)
0.0 0.2 GO:0016520 growth hormone-releasing hormone receptor activity(GO:0016520)
0.0 0.1 GO:0033300 dehydroascorbic acid transporter activity(GO:0033300)
0.0 0.1 GO:0003873 6-phosphofructo-2-kinase activity(GO:0003873)
0.0 0.1 GO:0030292 protein tyrosine kinase inhibitor activity(GO:0030292)
0.0 0.1 GO:0008440 inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440) inositol trisphosphate kinase activity(GO:0051766)
0.0 0.2 GO:0050786 RAGE receptor binding(GO:0050786)
0.0 0.2 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.0 0.1 GO:0008745 N-acetylmuramoyl-L-alanine amidase activity(GO:0008745)
0.0 0.1 GO:0044020 histone methyltransferase activity (H4-R3 specific)(GO:0044020)
0.0 0.2 GO:0004703 G-protein coupled receptor kinase activity(GO:0004703)
0.0 0.1 GO:0032296 ribonuclease III activity(GO:0004525) double-stranded RNA-specific ribonuclease activity(GO:0032296)
0.0 0.3 GO:0051018 protein kinase A binding(GO:0051018)
0.0 0.1 GO:0032137 guanine/thymine mispair binding(GO:0032137)
0.0 0.4 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.0 0.1 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.0 0.1 GO:0018685 alkane 1-monooxygenase activity(GO:0018685)
0.0 0.1 GO:0004950 G-protein coupled chemoattractant receptor activity(GO:0001637) chemokine receptor activity(GO:0004950)
0.0 0.1 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.0 0.2 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.0 0.1 GO:0004774 succinate-CoA ligase activity(GO:0004774)
0.0 0.1 GO:0001595 angiotensin receptor activity(GO:0001595) angiotensin type II receptor activity(GO:0004945)
0.0 0.3 GO:0015924 mannosyl-oligosaccharide mannosidase activity(GO:0015924)
0.0 0.2 GO:0003857 3-hydroxyacyl-CoA dehydrogenase activity(GO:0003857)
0.0 0.2 GO:0005041 low-density lipoprotein receptor activity(GO:0005041)
0.0 0.1 GO:0004994 somatostatin receptor activity(GO:0004994)
0.0 0.1 GO:0004142 diacylglycerol cholinephosphotransferase activity(GO:0004142)
0.0 0.1 GO:0017159 pantetheine hydrolase activity(GO:0017159)
0.0 0.1 GO:0050542 icosanoid binding(GO:0050542) fatty acid derivative binding(GO:1901567)
0.0 0.3 GO:0010181 FMN binding(GO:0010181)
0.0 0.1 GO:0016174 NAD(P)H oxidase activity(GO:0016174)
0.0 0.1 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
0.0 0.1 GO:0001012 transcription regulatory region sequence-specific DNA binding(GO:0000976) RNA polymerase II regulatory region sequence-specific DNA binding(GO:0000977) RNA polymerase II regulatory region DNA binding(GO:0001012)
0.0 0.1 GO:0005314 high-affinity glutamate transmembrane transporter activity(GO:0005314)
0.0 0.2 GO:0015347 sodium-independent organic anion transmembrane transporter activity(GO:0015347)
0.0 0.2 GO:0004550 nucleoside diphosphate kinase activity(GO:0004550)
0.0 0.2 GO:0051635 obsolete bacterial cell surface binding(GO:0051635)
0.0 0.1 GO:0004047 aminomethyltransferase activity(GO:0004047)
0.0 0.1 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
0.0 0.1 GO:0004167 dopachrome isomerase activity(GO:0004167)
0.0 0.2 GO:0019864 IgG binding(GO:0019864)
0.0 0.1 GO:0046974 histone methyltransferase activity (H3-K9 specific)(GO:0046974)
0.0 0.2 GO:0034593 phosphatidylinositol bisphosphate phosphatase activity(GO:0034593)
0.0 0.1 GO:0042289 MHC class II protein binding(GO:0042289)
0.0 0.3 GO:0019534 toxin transporter activity(GO:0019534)
0.0 0.1 GO:0008273 calcium, potassium:sodium antiporter activity(GO:0008273)
0.0 0.6 GO:0003725 double-stranded RNA binding(GO:0003725)
0.0 0.1 GO:0016530 metallochaperone activity(GO:0016530)
0.0 0.1 GO:0070653 high-density lipoprotein particle receptor binding(GO:0070653)
0.0 0.1 GO:0004459 L-lactate dehydrogenase activity(GO:0004459)
0.0 0.1 GO:0016416 carnitine O-palmitoyltransferase activity(GO:0004095) O-palmitoyltransferase activity(GO:0016416)
0.0 0.1 GO:0004985 opioid receptor activity(GO:0004985)
0.0 0.2 GO:0005522 profilin binding(GO:0005522)
0.0 0.1 GO:0015193 L-proline transmembrane transporter activity(GO:0015193)
0.0 0.1 GO:0004833 tryptophan 2,3-dioxygenase activity(GO:0004833)
0.0 0.2 GO:0030159 receptor signaling complex scaffold activity(GO:0030159)
0.0 0.1 GO:0004301 epoxide hydrolase activity(GO:0004301)
0.0 0.1 GO:0004566 beta-glucuronidase activity(GO:0004566)
0.0 0.3 GO:0008484 sulfuric ester hydrolase activity(GO:0008484)
0.0 0.3 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.0 0.2 GO:0030280 structural constituent of epidermis(GO:0030280)
0.0 0.3 GO:0031593 polyubiquitin binding(GO:0031593)
0.0 0.1 GO:0070053 thrombospondin receptor activity(GO:0070053)
0.0 1.0 GO:0008301 DNA binding, bending(GO:0008301)
0.0 0.1 GO:0051192 ACP phosphopantetheine attachment site binding involved in fatty acid biosynthetic process(GO:0000036) ACP phosphopantetheine attachment site binding(GO:0044620) prosthetic group binding(GO:0051192)
0.0 0.1 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.0 0.0 GO:0035173 histone kinase activity(GO:0035173)
0.0 0.2 GO:0004602 glutathione peroxidase activity(GO:0004602)
0.0 0.3 GO:0002039 p53 binding(GO:0002039)
0.0 0.2 GO:0005246 calcium channel regulator activity(GO:0005246)
0.0 0.1 GO:0000832 inositol hexakisphosphate kinase activity(GO:0000828) inositol hexakisphosphate 5-kinase activity(GO:0000832)
0.0 0.1 GO:0005087 Ran guanyl-nucleotide exchange factor activity(GO:0005087)
0.0 0.1 GO:0046790 virion binding(GO:0046790)
0.0 0.1 GO:0004738 pyruvate dehydrogenase activity(GO:0004738) pyruvate dehydrogenase (acetyl-transferring) activity(GO:0004739)
0.0 0.0 GO:0008179 adenylate cyclase binding(GO:0008179)
0.0 0.0 GO:0030229 very-low-density lipoprotein particle receptor activity(GO:0030229)
0.0 0.1 GO:0003988 acetyl-CoA C-acyltransferase activity(GO:0003988)
0.0 0.1 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.0 0.1 GO:0031014 troponin T binding(GO:0031014)
0.0 0.1 GO:0016857 racemase and epimerase activity, acting on carbohydrates and derivatives(GO:0016857)
0.0 0.1 GO:0043422 protein kinase B binding(GO:0043422)
0.0 0.1 GO:0008409 5'-3' exonuclease activity(GO:0008409)
0.0 0.0 GO:0016453 C-acetyltransferase activity(GO:0016453)
0.0 0.1 GO:0042156 obsolete zinc-mediated transcriptional activator activity(GO:0042156)
0.0 0.1 GO:0005521 lamin binding(GO:0005521)
0.0 0.1 GO:0050664 oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor(GO:0050664)
0.0 0.1 GO:0070491 repressing transcription factor binding(GO:0070491)
0.0 0.3 GO:0070001 aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001)
0.0 0.1 GO:0003917 DNA topoisomerase type I activity(GO:0003917)
0.0 0.1 GO:0047631 ADP-ribose diphosphatase activity(GO:0047631)
0.0 0.1 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.0 0.8 GO:0042393 histone binding(GO:0042393)
0.0 0.0 GO:0004514 nicotinate-nucleotide diphosphorylase (carboxylating) activity(GO:0004514)
0.0 0.0 GO:0008821 crossover junction endodeoxyribonuclease activity(GO:0008821)
0.0 0.1 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.0 0.1 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.0 0.1 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.0 0.0 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.0 0.1 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.0 0.2 GO:0051059 NF-kappaB binding(GO:0051059)
0.0 0.2 GO:0032452 histone demethylase activity(GO:0032452)
0.0 0.1 GO:0005047 signal recognition particle binding(GO:0005047)
0.0 0.0 GO:0034481 chondroitin sulfotransferase activity(GO:0034481)
0.0 0.0 GO:0016886 ligase activity, forming phosphoric ester bonds(GO:0016886)
0.0 0.1 GO:0008889 glycerophosphodiester phosphodiesterase activity(GO:0008889)
0.0 0.1 GO:0016670 oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor(GO:0016670)
0.0 0.1 GO:0003906 DNA-(apurinic or apyrimidinic site) lyase activity(GO:0003906)
0.0 0.1 GO:0001228 transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0000982) transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077) transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.0 0.1 GO:0070567 cytidylyltransferase activity(GO:0070567)
0.0 0.2 GO:0019205 nucleobase-containing compound kinase activity(GO:0019205)
0.0 0.0 GO:1990939 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574) ATP-dependent microtubule motor activity(GO:1990939)
0.0 0.0 GO:0005275 amine transmembrane transporter activity(GO:0005275)
0.0 0.1 GO:0008073 ornithine decarboxylase inhibitor activity(GO:0008073)
0.0 0.0 GO:0035514 DNA demethylase activity(GO:0035514) DNA-N1-methyladenine dioxygenase activity(GO:0043734)
0.0 0.0 GO:0030911 TPR domain binding(GO:0030911)
0.0 0.2 GO:0001619 obsolete lysosphingolipid and lysophosphatidic acid receptor activity(GO:0001619)
0.0 0.2 GO:0005487 nucleocytoplasmic transporter activity(GO:0005487)
0.0 0.2 GO:0046875 ephrin receptor binding(GO:0046875)
0.0 0.1 GO:0017169 CDP-alcohol phosphatidyltransferase activity(GO:0017169)
0.0 0.0 GO:0000064 L-ornithine transmembrane transporter activity(GO:0000064)
0.0 0.8 GO:0004197 cysteine-type endopeptidase activity(GO:0004197)
0.0 1.0 GO:0008565 protein transporter activity(GO:0008565)
0.0 0.2 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.0 0.1 GO:0030020 extracellular matrix structural constituent conferring tensile strength(GO:0030020)
0.0 0.3 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.0 0.1 GO:0003997 acyl-CoA oxidase activity(GO:0003997)
0.0 0.2 GO:0003756 protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864)
0.0 0.1 GO:0008195 phosphatidate phosphatase activity(GO:0008195)
0.0 0.1 GO:0004596 peptide alpha-N-acetyltransferase activity(GO:0004596)
0.0 0.1 GO:0004594 pantothenate kinase activity(GO:0004594)
0.0 0.0 GO:0016882 cyclo-ligase activity(GO:0016882)
0.0 0.2 GO:0050699 WW domain binding(GO:0050699)
0.0 0.1 GO:0017110 nucleoside-diphosphatase activity(GO:0017110)
0.0 0.0 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.0 0.2 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.0 0.0 GO:0005092 GDP-dissociation inhibitor activity(GO:0005092)
0.0 0.0 GO:0031434 mitogen-activated protein kinase kinase binding(GO:0031434)
0.0 0.0 GO:0042808 obsolete neuronal Cdc2-like kinase binding(GO:0042808)
0.0 0.0 GO:0008235 metalloexopeptidase activity(GO:0008235)
0.0 0.4 GO:0005044 scavenger receptor activity(GO:0005044)
0.0 0.0 GO:0003953 NAD+ nucleosidase activity(GO:0003953)
0.0 0.0 GO:0015272 ATP-activated inward rectifier potassium channel activity(GO:0015272)
0.0 0.1 GO:0003847 1-alkyl-2-acetylglycerophosphocholine esterase activity(GO:0003847)
0.0 0.2 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.0 0.0 GO:0004127 cytidylate kinase activity(GO:0004127)
0.0 0.0 GO:0004457 lactate dehydrogenase activity(GO:0004457)
0.0 0.1 GO:0019213 deacetylase activity(GO:0019213)
0.0 0.1 GO:0061659 ubiquitin-ubiquitin ligase activity(GO:0034450) ubiquitin protein ligase activity(GO:0061630) ubiquitin-like protein ligase activity(GO:0061659)
0.0 0.1 GO:0030371 translation repressor activity(GO:0030371)
0.0 0.0 GO:0000400 four-way junction DNA binding(GO:0000400)
0.0 0.0 GO:0015254 glycerol channel activity(GO:0015254)
0.0 0.2 GO:0008483 transaminase activity(GO:0008483)
0.0 0.1 GO:0048365 Rac GTPase binding(GO:0048365)
0.0 0.2 GO:0004889 acetylcholine-activated cation-selective channel activity(GO:0004889)
0.0 0.1 GO:0016409 palmitoyltransferase activity(GO:0016409)
0.0 0.2 GO:0000030 mannosyltransferase activity(GO:0000030)
0.0 0.1 GO:0005132 type I interferon receptor binding(GO:0005132)
0.0 0.2 GO:0016776 phosphotransferase activity, phosphate group as acceptor(GO:0016776)
0.0 0.1 GO:0008171 O-methyltransferase activity(GO:0008171)
0.0 0.2 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435)
0.0 0.2 GO:0005484 SNAP receptor activity(GO:0005484)
0.0 0.0 GO:0004427 inorganic diphosphatase activity(GO:0004427)
0.0 0.0 GO:0005412 glucose:sodium symporter activity(GO:0005412)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 5.7 PID CD8 TCR PATHWAY TCR signaling in naïve CD8+ T cells
0.1 2.0 PID IL2 STAT5 PATHWAY IL2 signaling events mediated by STAT5
0.1 0.1 PID P38 ALPHA BETA PATHWAY Regulation of p38-alpha and p38-beta
0.1 1.0 PID TCR PATHWAY TCR signaling in naïve CD4+ T cells
0.1 0.2 PID INTEGRIN3 PATHWAY Beta3 integrin cell surface interactions
0.1 0.6 SA PTEN PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.1 2.3 PID NFAT 3PATHWAY Role of Calcineurin-dependent NFAT signaling in lymphocytes
0.0 0.1 PID IL5 PATHWAY IL5-mediated signaling events
0.0 0.0 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.0 0.4 PID RANBP2 PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.0 0.6 PID LPA4 PATHWAY LPA4-mediated signaling events
0.0 0.1 PID BETA CATENIN DEG PATHWAY Degradation of beta catenin
0.0 1.0 PID BCR 5PATHWAY BCR signaling pathway
0.0 0.2 SA FAS SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.0 1.4 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0 0.2 PID ERBB4 PATHWAY ErbB4 signaling events
0.0 0.4 SA B CELL RECEPTOR COMPLEXES Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.0 0.7 PID GMCSF PATHWAY GMCSF-mediated signaling events
0.0 0.5 PID IL2 1PATHWAY IL2-mediated signaling events
0.0 0.7 PID MYC PATHWAY C-MYC pathway
0.0 0.6 SIG PIP3 SIGNALING IN B LYMPHOCYTES Genes related to PIP3 signaling in B lymphocytes
0.0 0.4 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.0 0.8 PID IL8 CXCR2 PATHWAY IL8- and CXCR2-mediated signaling events
0.0 0.6 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.0 0.2 ST TYPE I INTERFERON PATHWAY Type I Interferon (alpha/beta IFN) Pathway
0.0 0.1 PID INTEGRIN CS PATHWAY Integrin family cell surface interactions
0.0 0.7 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0 0.2 ST PHOSPHOINOSITIDE 3 KINASE PATHWAY PI3K Pathway
0.0 0.7 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.0 0.6 PID HDAC CLASSII PATHWAY Signaling events mediated by HDAC Class II
0.0 0.5 PID EPHRINB REV PATHWAY Ephrin B reverse signaling
0.0 0.3 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0 0.4 PID WNT CANONICAL PATHWAY Canonical Wnt signaling pathway
0.0 0.4 PID WNT NONCANONICAL PATHWAY Noncanonical Wnt signaling pathway
0.0 0.4 PID ARF6 PATHWAY Arf6 signaling events
0.0 0.2 PID NFKAPPAB CANONICAL PATHWAY Canonical NF-kappaB pathway
0.0 0.2 PID FAS PATHWAY FAS (CD95) signaling pathway
0.0 0.1 PID CD40 PATHWAY CD40/CD40L signaling
0.0 0.2 PID TRAIL PATHWAY TRAIL signaling pathway
0.0 0.3 PID PI3KCI PATHWAY Class I PI3K signaling events
0.0 0.1 ST INTERFERON GAMMA PATHWAY Interferon gamma pathway.
0.0 0.6 PID LKB1 PATHWAY LKB1 signaling events
0.0 0.1 SIG CD40PATHWAYMAP Genes related to CD40 signaling
0.0 0.1 PID IL1 PATHWAY IL1-mediated signaling events
0.0 0.4 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.0 0.0 PID PI3KCI AKT PATHWAY Class I PI3K signaling events mediated by Akt
0.0 0.1 ST JNK MAPK PATHWAY JNK MAPK Pathway
0.0 0.1 PID ATR PATHWAY ATR signaling pathway
0.0 0.0 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.0 0.0 PID INTEGRIN1 PATHWAY Beta1 integrin cell surface interactions
0.0 0.1 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.0 0.3 PID CERAMIDE PATHWAY Ceramide signaling pathway
0.0 0.1 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.0 0.1 ST DIFFERENTIATION PATHWAY IN PC12 CELLS Differentiation Pathway in PC12 Cells; this is a specific case of PAC1 Receptor Pathway.
0.0 0.2 PID DNA PK PATHWAY DNA-PK pathway in nonhomologous end joining
0.0 0.2 PID SYNDECAN 2 PATHWAY Syndecan-2-mediated signaling events
0.0 0.1 PID IL2 PI3K PATHWAY IL2 signaling events mediated by PI3K
0.0 0.1 PID IL3 PATHWAY IL3-mediated signaling events
0.0 0.0 SIG BCR SIGNALING PATHWAY Members of the BCR signaling pathway
0.0 0.3 PID ERBB1 INTERNALIZATION PATHWAY Internalization of ErbB1
0.0 2.2 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 0.4 PID AR TF PATHWAY Regulation of Androgen receptor activity
0.0 0.5 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 0.1 SIG INSULIN RECEPTOR PATHWAY IN CARDIAC MYOCYTES Genes related to the insulin receptor pathway
0.0 0.2 PID TXA2PATHWAY Thromboxane A2 receptor signaling
0.0 0.1 ST GAQ PATHWAY G alpha q Pathway
0.0 0.2 PID HIF1A PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.0 0.2 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway
0.0 0.2 PID INTEGRIN A4B1 PATHWAY Alpha4 beta1 integrin signaling events
0.0 0.2 PID IL6 7 PATHWAY IL6-mediated signaling events
0.0 0.4 PID P53 REGULATION PATHWAY p53 pathway
0.0 0.2 PID FCER1 PATHWAY Fc-epsilon receptor I signaling in mast cells
0.0 1.0 PID P53 DOWNSTREAM PATHWAY Direct p53 effectors
0.0 0.1 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
0.0 0.1 PID KIT PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
0.0 0.1 PID NETRIN PATHWAY Netrin-mediated signaling events
0.0 0.0 ST TUMOR NECROSIS FACTOR PATHWAY Tumor Necrosis Factor Pathway.
0.0 0.1 PID EPHB FWD PATHWAY EPHB forward signaling
0.0 0.2 PID CONE PATHWAY Visual signal transduction: Cones

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.5 REACTOME BINDING AND ENTRY OF HIV VIRION Genes involved in Binding and entry of HIV virion
0.1 1.6 REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.1 3.0 REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.1 2.1 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.1 1.1 REACTOME GENERATION OF SECOND MESSENGER MOLECULES Genes involved in Generation of second messenger molecules
0.1 1.2 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.1 0.1 REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
0.1 0.7 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.1 1.1 REACTOME GPVI MEDIATED ACTIVATION CASCADE Genes involved in GPVI-mediated activation cascade
0.1 0.3 REACTOME CD28 DEPENDENT VAV1 PATHWAY Genes involved in CD28 dependent Vav1 pathway
0.1 0.5 REACTOME PROSTANOID LIGAND RECEPTORS Genes involved in Prostanoid ligand receptors
0.1 0.1 REACTOME E2F MEDIATED REGULATION OF DNA REPLICATION Genes involved in E2F mediated regulation of DNA replication
0.1 0.1 REACTOME NUCLEOTIDE LIKE PURINERGIC RECEPTORS Genes involved in Nucleotide-like (purinergic) receptors
0.0 0.2 REACTOME NFKB ACTIVATION THROUGH FADD RIP1 PATHWAY MEDIATED BY CASPASE 8 AND10 Genes involved in NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10
0.0 0.4 REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.0 0.2 REACTOME REGULATION OF IFNA SIGNALING Genes involved in Regulation of IFNA signaling
0.0 0.2 REACTOME RIP MEDIATED NFKB ACTIVATION VIA DAI Genes involved in RIP-mediated NFkB activation via DAI
0.0 0.4 REACTOME E2F ENABLED INHIBITION OF PRE REPLICATION COMPLEX FORMATION Genes involved in E2F-enabled inhibition of pre-replication complex formation
0.0 0.1 REACTOME IRAK1 RECRUITS IKK COMPLEX Genes involved in IRAK1 recruits IKK complex
0.0 0.7 REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION Genes involved in activated TAK1 mediates p38 MAPK activation
0.0 0.4 REACTOME TRAF6 MEDIATED NFKB ACTIVATION Genes involved in TRAF6 mediated NF-kB activation
0.0 0.4 REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY Genes involved in Adenylate cyclase activating pathway
0.0 0.3 REACTOME EICOSANOID LIGAND BINDING RECEPTORS Genes involved in Eicosanoid ligand-binding receptors
0.0 0.8 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.0 0.6 REACTOME IL RECEPTOR SHC SIGNALING Genes involved in Interleukin receptor SHC signaling
0.0 0.8 REACTOME REGULATORY RNA PATHWAYS Genes involved in Regulatory RNA pathways
0.0 0.7 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor
0.0 0.3 REACTOME DOWNSTREAM TCR SIGNALING Genes involved in Downstream TCR signaling
0.0 1.7 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0 0.3 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
0.0 0.5 REACTOME TRAF3 DEPENDENT IRF ACTIVATION PATHWAY Genes involved in TRAF3-dependent IRF activation pathway
0.0 0.2 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.0 0.0 REACTOME ENDOSOMAL VACUOLAR PATHWAY Genes involved in Endosomal/Vacuolar pathway
0.0 1.5 REACTOME INTERFERON GAMMA SIGNALING Genes involved in Interferon gamma signaling
0.0 0.3 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.0 0.5 REACTOME INFLAMMASOMES Genes involved in Inflammasomes
0.0 0.1 REACTOME CDT1 ASSOCIATION WITH THE CDC6 ORC ORIGIN COMPLEX Genes involved in CDT1 association with the CDC6:ORC:origin complex
0.0 0.6 REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE Genes involved in Synthesis of PIPs at the plasma membrane
0.0 0.3 REACTOME THE ROLE OF NEF IN HIV1 REPLICATION AND DISEASE PATHOGENESIS Genes involved in The role of Nef in HIV-1 replication and disease pathogenesis
0.0 0.4 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.0 1.1 REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.0 0.2 REACTOME IL 2 SIGNALING Genes involved in Interleukin-2 signaling
0.0 1.2 REACTOME P53 INDEPENDENT G1 S DNA DAMAGE CHECKPOINT Genes involved in p53-Independent G1/S DNA damage checkpoint
0.0 1.3 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.0 0.6 REACTOME KERATAN SULFATE KERATIN METABOLISM Genes involved in Keratan sulfate/keratin metabolism
0.0 0.0 REACTOME DAG AND IP3 SIGNALING Genes involved in DAG and IP3 signaling
0.0 0.8 REACTOME GLYCOSPHINGOLIPID METABOLISM Genes involved in Glycosphingolipid metabolism
0.0 0.3 REACTOME P2Y RECEPTORS Genes involved in P2Y receptors
0.0 0.2 REACTOME PKA MEDIATED PHOSPHORYLATION OF CREB Genes involved in PKA-mediated phosphorylation of CREB
0.0 0.6 REACTOME COSTIMULATION BY THE CD28 FAMILY Genes involved in Costimulation by the CD28 family
0.0 0.4 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.0 0.4 REACTOME CHONDROITIN SULFATE BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
0.0 0.2 REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR Genes involved in Trafficking and processing of endosomal TLR
0.0 0.4 REACTOME RECYCLING PATHWAY OF L1 Genes involved in Recycling pathway of L1
0.0 0.2 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.0 0.5 REACTOME METAL ION SLC TRANSPORTERS Genes involved in Metal ion SLC transporters
0.0 0.9 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.0 0.3 REACTOME REGULATION OF AMPK ACTIVITY VIA LKB1 Genes involved in Regulation of AMPK activity via LKB1
0.0 0.1 REACTOME CIRCADIAN CLOCK Genes involved in Circadian Clock
0.0 0.0 REACTOME CDK MEDIATED PHOSPHORYLATION AND REMOVAL OF CDC6 Genes involved in CDK-mediated phosphorylation and removal of Cdc6
0.0 0.2 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.0 0.3 REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.0 0.3 REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS Genes involved in Trafficking of GluR2-containing AMPA receptors
0.0 0.1 REACTOME DSCAM INTERACTIONS Genes involved in DSCAM interactions
0.0 0.1 REACTOME CTNNB1 PHOSPHORYLATION CASCADE Genes involved in Beta-catenin phosphorylation cascade
0.0 0.3 REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.0 0.3 REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.0 0.5 REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.0 0.2 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.0 0.4 REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 3 PROMOTER Genes involved in RNA Polymerase III Transcription Initiation From Type 3 Promoter
0.0 0.4 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.0 0.8 REACTOME DEFENSINS Genes involved in Defensins
0.0 0.1 REACTOME PIP3 ACTIVATES AKT SIGNALING Genes involved in PIP3 activates AKT signaling
0.0 0.3 REACTOME FANCONI ANEMIA PATHWAY Genes involved in Fanconi Anemia pathway
0.0 0.4 REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.0 0.4 REACTOME REGULATION OF BETA CELL DEVELOPMENT Genes involved in Regulation of beta-cell development
0.0 0.2 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
0.0 0.3 REACTOME RORA ACTIVATES CIRCADIAN EXPRESSION Genes involved in RORA Activates Circadian Expression
0.0 0.1 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GLP1 Genes involved in Synthesis, Secretion, and Inactivation of Glucagon-like Peptide-1 (GLP-1)
0.0 0.1 REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.0 0.3 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.0 0.2 REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
0.0 0.0 REACTOME REGULATION OF INSULIN SECRETION BY GLUCAGON LIKE PEPTIDE1 Genes involved in Regulation of Insulin Secretion by Glucagon-like Peptide-1
0.0 0.1 REACTOME RAP1 SIGNALLING Genes involved in Rap1 signalling
0.0 0.2 REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.0 0.3 REACTOME KINESINS Genes involved in Kinesins
0.0 0.3 REACTOME TRANSPORT TO THE GOLGI AND SUBSEQUENT MODIFICATION Genes involved in Transport to the Golgi and subsequent modification
0.0 0.1 REACTOME ASSEMBLY OF THE PRE REPLICATIVE COMPLEX Genes involved in Assembly of the pre-replicative complex
0.0 1.3 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.0 0.4 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.0 0.0 REACTOME DOPAMINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Dopamine Neurotransmitter Release Cycle
0.0 0.2 REACTOME G0 AND EARLY G1 Genes involved in G0 and Early G1
0.0 0.1 REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE Genes involved in Synthesis of PIPs at the Golgi membrane
0.0 0.4 REACTOME INWARDLY RECTIFYING K CHANNELS Genes involved in Inwardly rectifying K+ channels
0.0 0.1 REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.0 0.2 REACTOME HIGHLY CALCIUM PERMEABLE POSTSYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Highly calcium permeable postsynaptic nicotinic acetylcholine receptors
0.0 0.6 REACTOME PACKAGING OF TELOMERE ENDS Genes involved in Packaging Of Telomere Ends
0.0 0.5 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import
0.0 0.2 REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING Genes involved in Formation of ATP by chemiosmotic coupling
0.0 0.0 REACTOME REGULATED PROTEOLYSIS OF P75NTR Genes involved in Regulated proteolysis of p75NTR
0.0 0.1 REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.0 0.5 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.0 0.7 REACTOME RESPIRATORY ELECTRON TRANSPORT ATP SYNTHESIS BY CHEMIOSMOTIC COUPLING AND HEAT PRODUCTION BY UNCOUPLING PROTEINS Genes involved in Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins.
0.0 0.2 REACTOME RIG I MDA5 MEDIATED INDUCTION OF IFN ALPHA BETA PATHWAYS Genes involved in RIG-I/MDA5 mediated induction of IFN-alpha/beta pathways
0.0 0.1 REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
0.0 0.2 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.0 0.1 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.0 0.2 REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.0 0.1 REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.0 0.2 REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.0 0.0 REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK Genes involved in Negative regulation of the PI3K/AKT network