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ENCODE: H3K4me1 ChIP-Seq of primary human cells

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CREMA is a free online tool that recognizes most important transcription factors that change the chromatin state across different samples.

Results for OTX2_CRX

Z-value: 1.48

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Transcription factors associated with OTX2_CRX

Gene Symbol	Gene ID	Gene Info
OTX2 Ensembl NCBI GeneCards UniProt	ENSG00000165588.12	OTX2
CRX Ensembl NCBI GeneCards UniProt	ENSG00000105392.11	CRX

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE	Gene	Distance	Association probability	Pearson corr. coef.	P-value	Plot
OTX2	chr14_57264264_57264415	8027	0.169813	-0.61	8.2e-02	Click!
OTX2	chr14_57263392_57263543	8899	0.168034	-0.56	1.2e-01	Click!
OTX2	chr14_57262189_57262340	10102	0.166133	-0.47	2.0e-01	Click!
OTX2	chr14_57274823_57275045	2232	0.254600	-0.41	2.7e-01	Click!
OTX2	chr14_57274493_57274644	2187	0.259421	-0.38	3.2e-01	Click!

Activity of the OTX2_CRX motif across conditions

Conditions sorted by the z-value of the OTX2_CRX motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE)	Target Score	Top associated gene	Gene Info	Distance of CRE to TSS	CRE/Gene association probability
chr2_43152776_43153425	0.71	HAAO	3-hydroxyanthranilate 3,4-dioxygenase	133368	0.05
chr19_47478570_47478952	0.63	ENSG00000252071	.	27215	0.14
chr12_11733022_11733284	0.58	ENSG00000251747	.	33740	0.16
chr1_201426596_201426747	0.56	PHLDA3	pleckstrin homology-like domain, family A, member 3	11641	0.15
chr14_53301825_53302222	0.53	FERMT2	fermitin family member 2	29216	0.15
chr20_34489809_34489960	0.53	ENSG00000201221	.	14303	0.13
chr17_30068402_30068553	0.45	ENSG00000202026	.	27705	0.19
chr15_46162513_46162674	0.45	SQRDL	sulfide quinone reductase-like (yeast)	187855	0.03
chr6_130645263_130645558	0.42	SAMD3	sterile alpha motif domain containing 3	41160	0.17
chr22_27531516_27531667	0.42	ENSG00000200443	.	99741	0.09
chr4_169496141_169496292	0.39	PALLD	palladin, cytoskeletal associated protein	56550	0.12
chr4_122705792_122706078	0.38	EXOSC9	exosome component 9	16537	0.14
chr5_64493902_64494516	0.38	ENSG00000207439	.	75013	0.12
chr4_39525693_39526119	0.38	UGDH	UDP-glucose 6-dehydrogenase	2271	0.25
chr8_12583298_12583449	0.35	ENSG00000266206	.	1440	0.38
chr1_208382716_208382867	0.35	PLXNA2	plexin A2	34874	0.24
chr1_21478340_21478712	0.35	EIF4G3	eukaryotic translation initiation factor 4 gamma, 3	22704	0.19
chr9_16795794_16795945	0.35	BNC2	basonuclin 2	36417	0.21
chr3_170470237_170470470	0.35	ENSG00000222411	.	89608	0.08
chr11_19420172_19420323	0.35	ENSG00000200687	.	3281	0.25
chr11_82690749_82690900	0.35	PRCP	prolylcarboxypeptidase (angiotensinase C)	9198	0.18
chr14_80050698_80050849	0.34	RP11-242P2.2		48881	0.19
chr14_69544397_69544681	0.34	ENSG00000206768	.	66131	0.1
chr11_19222231_19222783	0.34	CSRP3	cysteine and glycine-rich protein 3 (cardiac LIM protein)	1082	0.5
chr12_1427689_1428011	0.34	RP5-951N9.2		67149	0.11
chr6_82476723_82477129	0.34	ENSG00000206886	.	3185	0.27
chr5_148352238_148352777	0.34	RP11-44B19.1		2604	0.3
chr5_81460698_81461288	0.33	ENSG00000265684	.	86747	0.08
chr1_67397953_67399117	0.33	MIER1	mesoderm induction early response 1, transcriptional regulator	2609	0.29
chr17_73690444_73690713	0.33	SAP30BP	SAP30 binding protein	1952	0.18
chr1_86020329_86020665	0.33	DDAH1	dimethylarginine dimethylaminohydrolase 1	23436	0.17
chr5_95004855_95005067	0.32	SPATA9	spermatogenesis associated 9	13699	0.16
chr2_28497749_28498516	0.32	AC093690.1		35194	0.19
chr5_159305915_159306327	0.32	ADRA1B	adrenoceptor alpha 1B	37669	0.2
chr8_97603049_97603490	0.32	SDC2	syndecan 2	4654	0.31
chr1_171096536_171096687	0.31	FMO6P	flavin containing monooxygenase 6 pseudogene	10630	0.16
chr5_64500241_64500433	0.31	ENSG00000207439	.	81141	0.11
chr1_59481843_59482033	0.31	JUN	jun proto-oncogene	232153	0.02
chr12_110493934_110494306	0.31	C12orf76	chromosome 12 open reading frame 76	7030	0.2
chr5_57134395_57134546	0.31	ENSG00000266864	.	34403	0.24
chr22_36369506_36369746	0.31	RBFOX2	RNA binding protein, fox-1 homolog (C. elegans) 2	11912	0.28
chr2_159996739_159997187	0.31	ENSG00000202029	.	113309	0.06
chr8_119017458_119017609	0.31	EXT1	exostosin glycosyltransferase 1	105120	0.08
chr2_206577775_206577938	0.30	NRP2	neuropilin 2	29841	0.21
chr10_34393778_34393929	0.30	ENSG00000199200	.	97149	0.09
chr10_35021138_35021390	0.30	PARD3	par-3 family cell polarity regulator	82985	0.1
chr19_43493188_43493339	0.30	PSG11	pregnancy specific beta-1-glycoprotein 11	37337	0.15
chr5_34487773_34488055	0.30	RAI14	retinoic acid induced 14	168428	0.03
chr6_35393359_35394053	0.30	FANCE	Fanconi anemia, complementation group E	26432	0.15
chr8_10657129_10657397	0.30	ENSG00000252565	.	15698	0.15
chr6_110417870_110418143	0.30	WASF1	WAS protein family, member 1	82846	0.09
chr9_14271441_14271727	0.29	NFIB	nuclear factor I/B	36428	0.2
chr2_162949372_162949523	0.29	DPP4	dipeptidyl-peptidase 4	18395	0.18
chr11_130642757_130642947	0.29	C11orf44	chromosome 11 open reading frame 44	100001	0.08
chr11_86447090_86447241	0.29	PRSS23	protease, serine, 23	54936	0.15
chr8_37783052_37783203	0.29	GOT1L1	glutamic-oxaloacetic transaminase 1-like 1	11204	0.13
chr9_74299304_74300206	0.29	TMEM2	transmembrane protein 2	20093	0.28
chr18_68088910_68089061	0.28	ENSG00000264059	.	59526	0.13
chr15_35988877_35989028	0.28	DPH6	diphthamine biosynthesis 6	150559	0.05
chr12_13278087_13278467	0.28	GSG1	germ cell associated 1	21658	0.19
chrX_12378398_12378549	0.28	FRMPD4-AS1	FRMPD4 antisense RNA 1	14779	0.29
chr14_69013976_69014127	0.28	CTD-2325P2.4		81111	0.1
chr16_69098691_69098842	0.28	HAS3	hyaluronan synthase 3	40701	0.11
chr16_66652366_66652517	0.28	CMTM3	CKLF-like MARVEL transmembrane domain containing 3	13017	0.11
chr1_52024489_52024927	0.28	OSBPL9	oxysterol binding protein-like 9	18143	0.15
chr17_66755524_66755734	0.28	ENSG00000263690	.	7071	0.3
chr10_3570543_3570694	0.28	RP11-184A2.3		222641	0.02
chr9_14251628_14251779	0.28	NFIB	nuclear factor I/B	56309	0.15
chr8_104117274_104117548	0.28	ENSG00000265667	.	12462	0.13
chr2_196440572_196441282	0.28	SLC39A10	solute carrier family 39 (zinc transporter), member 10	226	0.96
chr2_227289868_227290019	0.27	ENSG00000263363	.	233566	0.02
chr12_110388287_110388838	0.27	GIT2	G protein-coupled receptor kinase interacting ArfGAP 2	45467	0.11
chr6_1575312_1575463	0.27	FOXC1	forkhead box C1	35294	0.21
chr5_169180771_169181008	0.27	DOCK2	dedicator of cytokinesis 2	5832	0.26
chr2_43496469_43496754	0.27	AC010883.5		39899	0.17
chr11_108786966_108787117	0.27	ENSG00000201243	.	89203	0.1
chr5_57032113_57032264	0.27	ENSG00000221195	.	93375	0.09
chr3_124849030_124849181	0.27	SLC12A8	solute carrier family 12, member 8	9407	0.17
chr12_66341786_66341937	0.27	RP11-366L20.3		398	0.86
chr9_111396759_111396910	0.27	ACTL7B	actin-like 7B	222405	0.02
chr16_11295567_11296301	0.27	RMI2	RecQ mediated genome instability 2	47572	0.08
chr6_38230519_38230766	0.27	ENSG00000200706	.	55592	0.15
chr1_30185013_30185164	0.27	ENSG00000221126	.	67563	0.14
chr1_158029342_158029493	0.27	KIRREL	kin of IRRE like (Drosophila)	27053	0.18
chr2_231481752_231482027	0.27	ENSG00000199791	.	30053	0.17
chr10_131821141_131821577	0.27	EBF3	early B-cell factor 3	59254	0.15
chr3_149469081_149469660	0.27	COMMD2	COMM domain containing 2	916	0.55
chr10_33505911_33506062	0.27	NRP1	neuropilin 1	3497	0.27
chr2_75120069_75120220	0.27	HK2	hexokinase 2	57847	0.12
chr3_174156335_174156660	0.27	NAALADL2	N-acetylated alpha-linked acidic dipeptidase-like 2	2280	0.47
chr17_79532915_79533078	0.27	NPLOC4	nuclear protein localization 4 homolog (S. cerevisiae)	632	0.54
chr9_84173660_84173811	0.27	TLE1	transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila)	54702	0.17
chr2_200274877_200275028	0.26	SATB2	SATB homeobox 2	45859	0.16
chr9_117715769_117716310	0.26	TNFSF8	tumor necrosis factor (ligand) superfamily, member 8	23342	0.24
chr12_53693833_53694662	0.26	RP11-680A11.5		149	0.73
chr6_43088179_43088500	0.26	PTK7	protein tyrosine kinase 7	9990	0.12
chr1_181047003_181047287	0.26	IER5	immediate early response 5	10493	0.21
chr4_129149985_129150136	0.26	PGRMC2	progesterone receptor membrane component 2	44156	0.2
chr3_111480055_111480487	0.26	PHLDB2	pleckstrin homology-like domain, family B, member 2	28927	0.2
chr15_40289924_40290075	0.26	EIF2AK4	eukaryotic translation initiation factor 2 alpha kinase 4	32595	0.12
chr4_152666058_152666209	0.26	PET112	PET112 homolog (yeast)	16004	0.24
chr2_160816916_160817067	0.26	LY75-CD302	LY75-CD302 readthrough	55770	0.13
chr4_171593437_171593770	0.26	ENSG00000251961	.	219015	0.02
chr12_66262478_66262882	0.26	ENSG00000211577	.	10887	0.18
chr5_39093457_39093608	0.26	AC008964.1		11826	0.23
chr2_183457874_183458025	0.26	PDE1A	phosphodiesterase 1A, calmodulin-dependent	70484	0.12
chr2_45926277_45926449	0.26	U51244.2		23748	0.22
chr16_11098719_11098870	0.26	CLEC16A	C-type lectin domain family 16, member A	60356	0.08
chr1_117690204_117690355	0.26	TRIM45	tripartite motif containing 45	25070	0.15
chr1_99922703_99922854	0.26	LPPR4	Lipid phosphate phosphatase-related protein type 4	158358	0.04
chr1_85805501_85805652	0.26	ENSG00000264380	.	55283	0.09
chr11_67979238_67979938	0.26	SUV420H1	suppressor of variegation 4-20 homolog 1 (Drosophila)	633	0.74
chr4_77956814_77956965	0.25	SEPT11	septin 11	7019	0.23
chr15_99994749_99995202	0.25	MEF2A	myocyte enhancer factor 2A	22395	0.18
chr6_3517760_3517987	0.25	SLC22A23	solute carrier family 22, member 23	60617	0.14
chr1_223584357_223584508	0.25	C1orf65	chromosome 1 open reading frame 65	17717	0.2
chr5_156943457_156943608	0.25	ADAM19	ADAM metallopeptidase domain 19	13702	0.17
chr10_81923875_81924026	0.25	ANXA11	annexin A11	2182	0.32
chr8_98941895_98942046	0.25	MATN2	matrilin 2	1599	0.45
chr12_71040955_71041106	0.25	PTPRB	protein tyrosine phosphatase, receptor type, B	9810	0.28
chr16_88836823_88837632	0.25	PIEZO1	piezo-type mechanosensitive ion channel component 1	14392	0.08
chr14_85937883_85938084	0.25	RP11-497E19.2	Uncharacterized protein	56960	0.15
chr15_74880720_74881033	0.25	CLK3	CDC-like kinase 3	19837	0.14
chr12_64400725_64400876	0.25	SRGAP1	SLIT-ROBO Rho GTPase activating protein 1	24495	0.2
chr11_131783724_131783875	0.25	NTM	neurotrimin	2437	0.34
chr14_55242379_55242669	0.25	SAMD4A	sterile alpha motif domain containing 4A	20973	0.23
chr16_30724842_30725097	0.25	ENSG00000206755	.	3111	0.11
chr17_40481304_40481455	0.25	STAT5A	signal transducer and activator of transcription 5A	23191	0.11
chr10_33418933_33419614	0.25	ENSG00000263576	.	31709	0.18
chr3_185450728_185450956	0.25	C3orf65	chromosome 3 open reading frame 65	19762	0.2
chr1_208293570_208293721	0.25	PLXNA2	plexin A2	124020	0.06
chr1_224716594_224716745	0.25	RP11-100E13.1		87253	0.07
chr3_69813399_69813761	0.25	MITF	microphthalmia-associated transcription factor	618	0.78
chr1_61427090_61427390	0.25	RP4-668G5.1		8719	0.29
chr9_37943494_37943645	0.25	ENSG00000251745	.	6804	0.24
chr5_72665716_72665867	0.25	FOXD1	forkhead box D1	78561	0.09
chr5_169002894_169003181	0.25	SPDL1	spindle apparatus coiled-coil protein 1	7601	0.23
chr2_188256029_188256180	0.25	CALCRL	calcitonin receptor-like	56875	0.15
chr3_105078554_105078705	0.25	ALCAM	activated leukocyte cell adhesion molecule	7124	0.35
chr7_82434629_82434780	0.24	PCLO	piccolo presynaptic cytomatrix protein	145360	0.05
chr9_73518177_73518328	0.24	TRPM3	transient receptor potential cation channel, subfamily M, member 3	34278	0.22
chr2_235213914_235214065	0.24	ARL4C	ADP-ribosylation factor-like 4C	191255	0.03
chr2_217180660_217180876	0.24	AC069155.1		12720	0.18
chr6_26103334_26103549	0.24	HIST1H4C	histone cluster 1, H4c	663	0.44
chr7_116417479_116417780	0.24	MET	met proto-oncogene	400	0.88
chr10_128613233_128613384	0.24	ENSG00000202487	.	3932	0.29
chr4_13478395_13478680	0.24	RAB28	RAB28, member RAS oncogene family	2568	0.38
chr6_52376418_52376603	0.24	TRAM2	translocation associated membrane protein 2	65203	0.11
chr15_39481396_39481547	0.24	C15orf54	chromosome 15 open reading frame 54	61414	0.14
chr4_152596771_152596922	0.24	RP11-164P12.3		1211	0.5
chr17_39215738_39215889	0.24	KRTAP2-3	keratin associated protein 2-3	531	0.48
chr12_52182216_52182367	0.24	AC068987.1	HCG1997999; cDNA FLJ33996 fis, clone DFNES2008881	21498	0.2
chr5_180213979_180214228	0.24	CTC-205M6.5		766	0.61
chr10_13981087_13981238	0.24	FRMD4A	FERM domain containing 4A	33207	0.19
chr10_30236708_30236859	0.24	KIAA1462	KIAA1462	111670	0.07
chr17_2082426_2082658	0.24	SMG6	SMG6 nonsense mediated mRNA decay factor	6070	0.13
chr13_95740200_95740570	0.24	ENSG00000252335	.	68896	0.12
chr16_70741421_70741612	0.24	VAC14	Vac14 homolog (S. cerevisiae)	7368	0.15
chr4_77468211_77468426	0.24	ENSG00000207307	.	14838	0.16
chr9_133640945_133641435	0.24	ABL1	c-abl oncogene 1, non-receptor tyrosine kinase	51823	0.13
chr8_41548916_41549067	0.24	ANK1	ankyrin 1, erythrocytic	14706	0.15
chr4_187767041_187767192	0.24	ENSG00000252382	.	11494	0.3
chr12_77425923_77426193	0.24	E2F7	E2F transcription factor 7	18468	0.27
chr14_61492762_61493358	0.24	SLC38A6	solute carrier family 38, member 6	16808	0.21
chr1_16505237_16505388	0.24	ARHGEF19-AS1	ARHGEF19 antisense RNA 1	19037	0.1
chr1_85950376_85950527	0.24	DDAH1	dimethylarginine dimethylaminohydrolase 1	19624	0.21
chr6_14286162_14286313	0.24	ENSG00000238987	.	129544	0.06
chr1_94429653_94429804	0.24	ABCA4	ATP-binding cassette, sub-family A (ABC1), member 4	47453	0.13
chrX_20085662_20085960	0.24	MAP7D2	MAP7 domain containing 2	10916	0.18
chr7_81476151_81476440	0.24	ENSG00000263416	.	73291	0.11
chr3_52205760_52205911	0.23	POC1A	POC1 centriolar protein A	17129	0.12
chr5_98396799_98396950	0.23	ENSG00000200351	.	124423	0.06
chr1_200341478_200341663	0.23	ZNF281	zinc finger protein 281	37550	0.22
chr5_114738428_114738579	0.23	CCDC112	coiled-coil domain containing 112	105975	0.06
chr21_18864726_18865102	0.23	ENSG00000266195	.	13857	0.15
chr6_11195366_11195517	0.23	RP3-510L9.1		21756	0.19
chr4_122613058_122613356	0.23	ANXA5	annexin A5	4910	0.26
chr8_123671514_123671802	0.23	ENSG00000238901	.	11872	0.28
chr5_121518729_121518882	0.23	CTC-441N14.1		27095	0.17
chr1_146638682_146638833	0.23	PRKAB2	protein kinase, AMP-activated, beta 2 non-catalytic subunit	5289	0.17
chr19_49554011_49554162	0.23	CGB8	chorionic gonadotropin, beta polypeptide 8	1686	0.12
chr18_46069398_46069549	0.23	CTIF	CBP80/20-dependent translation initiation factor	3007	0.33
chr13_110492993_110493226	0.23	IRS2	insulin receptor substrate 2	54194	0.15
chr8_18992583_18992734	0.23	PSD3	pleckstrin and Sec7 domain containing 3	50418	0.18
chr1_33809231_33809577	0.23	PHC2	polyhomeotic homolog 2 (Drosophila)	6082	0.12
chr9_127162086_127162596	0.23	PSMB7	proteasome (prosome, macropain) subunit, beta type, 7	15377	0.19
chr1_12524294_12524445	0.23	VPS13D	vacuolar protein sorting 13 homolog D (S. cerevisiae)	626	0.77
chr1_84719853_84720004	0.23	ENSG00000199959	.	23076	0.21
chr8_49292717_49292868	0.23	ENSG00000252710	.	72202	0.13
chr3_185463874_185464186	0.23	ENSG00000265470	.	21662	0.19
chr16_68333106_68333257	0.23	SLC7A6OS	solute carrier family 7, member 6 opposite strand	4951	0.09
chr1_54801806_54802163	0.23	RP5-997D24.3		50906	0.12
chr17_48138498_48138649	0.23	ITGA3	integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)	4769	0.15
chr1_178509729_178509880	0.23	C1orf220	chromosome 1 open reading frame 220	2083	0.23
chr13_27193375_27193609	0.23	WASF3-AS1	WASF3 antisense RNA 1	22009	0.24
chr15_64721787_64722615	0.23	TRIP4	thyroid hormone receptor interactor 4	5887	0.12
chr5_149886580_149886731	0.23	NDST1	N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1	1019	0.53
chr3_50138493_50138644	0.23	RBM5	RNA binding motif protein 5	10765	0.14
chr12_13357086_13357299	0.23	EMP1	epithelial membrane protein 1	7253	0.27
chrX_6962695_6962846	0.23	ENSG00000264268	.	103131	0.08

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of OTX2_CRX

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View png image

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	0.5	GO:0071694	sequestering of extracellular ligand from receptor(GO:0035581) sequestering of TGFbeta in extracellular matrix(GO:0035583) protein localization to extracellular region(GO:0071692) maintenance of protein location in extracellular region(GO:0071694) extracellular regulation of signal transduction(GO:1900115) extracellular negative regulation of signal transduction(GO:1900116)
0.1	0.6	GO:0060666	dichotomous subdivision of terminal units involved in salivary gland branching(GO:0060666)
0.1	0.2	GO:0060831	smoothened signaling pathway involved in dorsal/ventral neural tube patterning(GO:0060831)
0.1	0.4	GO:0031340	positive regulation of vesicle fusion(GO:0031340)
0.1	0.3	GO:0001996	positive regulation of heart rate by epinephrine-norepinephrine(GO:0001996)
0.1	0.3	GO:0032509	endosome transport via multivesicular body sorting pathway(GO:0032509)
0.1	0.4	GO:0048625	myoblast fate commitment(GO:0048625)
0.1	0.2	GO:0033173	calcineurin-NFAT signaling cascade(GO:0033173)
0.1	0.3	GO:0048702	embryonic neurocranium morphogenesis(GO:0048702)
0.1	0.2	GO:0060083	smooth muscle contraction involved in micturition(GO:0060083)
0.1	0.2	GO:0022605	oogenesis stage(GO:0022605)
0.1	0.1	GO:0060665	regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling(GO:0060665)
0.1	0.4	GO:0097061	dendritic spine morphogenesis(GO:0060997) regulation of dendritic spine morphogenesis(GO:0061001) dendritic spine organization(GO:0097061)
0.1	0.2	GO:0035426	extracellular matrix-cell signaling(GO:0035426)
0.1	0.2	GO:0072201	negative regulation of mesenchymal cell proliferation(GO:0072201)
0.1	0.2	GO:0010837	regulation of keratinocyte proliferation(GO:0010837)
0.1	0.2	GO:0010842	retina layer formation(GO:0010842)
0.1	0.4	GO:0007171	activation of transmembrane receptor protein tyrosine kinase activity(GO:0007171)
0.1	0.3	GO:0021535	cell migration in hindbrain(GO:0021535)
0.1	0.1	GO:0060648	mammary gland bud morphogenesis(GO:0060648)
0.1	0.2	GO:0015705	iodide transport(GO:0015705)
0.1	0.1	GO:0021825	cerebral cortex tangential migration using cell-cell interactions(GO:0021823) substrate-dependent cerebral cortex tangential migration(GO:0021825) postnatal olfactory bulb interneuron migration(GO:0021827)
0.1	0.2	GO:0007028	cytoplasm organization(GO:0007028)
0.1	0.2	GO:0019348	polyprenol metabolic process(GO:0016093) dolichol metabolic process(GO:0019348)
0.1	0.2	GO:0051124	synaptic growth at neuromuscular junction(GO:0051124)
0.1	0.2	GO:0010766	negative regulation of sodium ion transport(GO:0010766)
0.0	0.3	GO:0007185	transmembrane receptor protein tyrosine phosphatase signaling pathway(GO:0007185)
0.0	0.2	GO:0048755	branching morphogenesis of a nerve(GO:0048755)
0.0	0.2	GO:0048149	behavioral response to ethanol(GO:0048149)
0.0	0.1	GO:0006065	UDP-glucuronate biosynthetic process(GO:0006065)
0.0	0.2	GO:0060013	righting reflex(GO:0060013)
0.0	0.1	GO:2000114	regulation of establishment of cell polarity(GO:2000114)
0.0	0.2	GO:0051497	negative regulation of stress fiber assembly(GO:0051497)
0.0	0.1	GO:0045657	positive regulation of monocyte differentiation(GO:0045657)
0.0	0.1	GO:0033688	regulation of osteoblast proliferation(GO:0033688)
0.0	0.1	GO:0033603	positive regulation of dopamine secretion(GO:0033603)
0.0	0.1	GO:0035511	oxidative DNA demethylation(GO:0035511)
0.0	0.2	GO:0009128	purine nucleoside monophosphate catabolic process(GO:0009128) ribonucleoside monophosphate catabolic process(GO:0009158) purine ribonucleoside monophosphate catabolic process(GO:0009169)
0.0	0.1	GO:0055098	response to low-density lipoprotein particle(GO:0055098)
0.0	0.2	GO:0048343	paraxial mesodermal cell differentiation(GO:0048342) paraxial mesodermal cell fate commitment(GO:0048343)
0.0	0.2	GO:0090162	establishment of epithelial cell polarity(GO:0090162)
0.0	0.2	GO:0016266	O-glycan processing(GO:0016266)
0.0	0.2	GO:0071318	cellular response to ATP(GO:0071318)
0.0	0.1	GO:0003308	negative regulation of Wnt signaling pathway involved in heart development(GO:0003308)
0.0	0.1	GO:0071277	cellular response to calcium ion(GO:0071277)
0.0	0.1	GO:0070141	response to UV-A(GO:0070141)
0.0	0.1	GO:0010757	negative regulation of plasminogen activation(GO:0010757)
0.0	0.1	GO:0051014	actin filament severing(GO:0051014)
0.0	0.0	GO:0014067	negative regulation of phosphatidylinositol 3-kinase signaling(GO:0014067)
0.0	0.0	GO:2000542	negative regulation of gastrulation(GO:2000542)
0.0	0.1	GO:0060528	secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development(GO:0060528)
0.0	0.1	GO:0071800	podosome assembly(GO:0071800)
0.0	0.1	GO:0010761	fibroblast migration(GO:0010761)
0.0	0.1	GO:0007221	positive regulation of transcription of Notch receptor target(GO:0007221)
0.0	0.1	GO:0001543	ovarian follicle rupture(GO:0001543)
0.0	0.1	GO:0043490	malate-aspartate shuttle(GO:0043490)
0.0	0.1	GO:0010966	regulation of phosphate transport(GO:0010966)
0.0	0.0	GO:0035385	Roundabout signaling pathway(GO:0035385)
0.0	0.0	GO:0021798	forebrain dorsal/ventral pattern formation(GO:0021798)
0.0	0.0	GO:0060129	thyroid-stimulating hormone-secreting cell differentiation(GO:0060129)
0.0	0.2	GO:0048268	clathrin coat assembly(GO:0048268)
0.0	0.4	GO:0007026	negative regulation of microtubule depolymerization(GO:0007026)
0.0	0.1	GO:0046607	positive regulation of centrosome cycle(GO:0046607)
0.0	0.1	GO:0045074	interleukin-10 biosynthetic process(GO:0042091) regulation of interleukin-10 biosynthetic process(GO:0045074)
0.0	0.1	GO:2000050	regulation of non-canonical Wnt signaling pathway(GO:2000050) regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000095)
0.0	0.1	GO:0001973	adenosine receptor signaling pathway(GO:0001973) G-protein coupled purinergic receptor signaling pathway(GO:0035588)
0.0	0.1	GO:0032455	nerve growth factor processing(GO:0032455)
0.0	0.1	GO:0006663	platelet activating factor biosynthetic process(GO:0006663)
0.0	0.2	GO:0051382	kinetochore assembly(GO:0051382)
0.0	0.1	GO:0032347	regulation of ketone biosynthetic process(GO:0010566) regulation of aldosterone metabolic process(GO:0032344) regulation of aldosterone biosynthetic process(GO:0032347)
0.0	0.1	GO:0002903	negative regulation of B cell apoptotic process(GO:0002903)
0.0	0.1	GO:0006007	glucose catabolic process(GO:0006007)
0.0	0.1	GO:0032413	negative regulation of ion transmembrane transporter activity(GO:0032413)
0.0	0.1	GO:0051305	chromosome movement towards spindle pole(GO:0051305)
0.0	0.0	GO:0046121	deoxyribonucleoside catabolic process(GO:0046121)
0.0	0.1	GO:0016241	regulation of macroautophagy(GO:0016241)
0.0	0.2	GO:1904893	negative regulation of JAK-STAT cascade(GO:0046426) negative regulation of STAT cascade(GO:1904893)
0.0	0.0	GO:0001553	luteinization(GO:0001553)
0.0	0.1	GO:0045662	negative regulation of myoblast differentiation(GO:0045662)
0.0	0.1	GO:2000647	negative regulation of neuroblast proliferation(GO:0007406) negative regulation of neural precursor cell proliferation(GO:2000178) negative regulation of stem cell proliferation(GO:2000647)
0.0	0.1	GO:0043129	surfactant homeostasis(GO:0043129) chemical homeostasis within a tissue(GO:0048875)
0.0	0.1	GO:0019471	peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401) 4-hydroxyproline metabolic process(GO:0019471) peptidyl-proline hydroxylation(GO:0019511)
0.0	0.1	GO:0043589	skin morphogenesis(GO:0043589)
0.0	0.1	GO:0045747	positive regulation of Notch signaling pathway(GO:0045747)
0.0	0.1	GO:0010661	positive regulation of muscle cell apoptotic process(GO:0010661) positive regulation of smooth muscle cell apoptotic process(GO:0034393)
0.0	0.1	GO:0060058	apoptotic process involved in mammary gland involution(GO:0060057) positive regulation of apoptotic process involved in mammary gland involution(GO:0060058) positive regulation of apoptotic process involved in morphogenesis(GO:1902339) regulation of mammary gland involution(GO:1903519) positive regulation of mammary gland involution(GO:1903521) positive regulation of apoptotic process involved in development(GO:1904747)
0.0	0.1	GO:0002043	blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:0002043)
0.0	0.1	GO:0060394	negative regulation of pathway-restricted SMAD protein phosphorylation(GO:0060394)
0.0	0.1	GO:0045715	negative regulation of low-density lipoprotein particle receptor biosynthetic process(GO:0045715)
0.0	0.1	GO:0006048	UDP-N-acetylglucosamine biosynthetic process(GO:0006048)
0.0	0.1	GO:0002678	positive regulation of chronic inflammatory response(GO:0002678)
0.0	0.1	GO:0060039	pericardium development(GO:0060039)
0.0	0.1	GO:0072386	plus-end-directed vesicle transport along microtubule(GO:0072383) plus-end-directed organelle transport along microtubule(GO:0072386)
0.0	0.1	GO:0019805	quinolinate biosynthetic process(GO:0019805)
0.0	0.0	GO:0042637	catagen(GO:0042637)
0.0	0.1	GO:0070874	negative regulation of glycogen metabolic process(GO:0070874)
0.0	0.1	GO:0006910	phagocytosis, recognition(GO:0006910)
0.0	0.2	GO:0050957	equilibrioception(GO:0050957)
0.0	0.2	GO:0000052	citrulline metabolic process(GO:0000052)
0.0	0.0	GO:0061318	renal filtration cell differentiation(GO:0061318) glomerular epithelium development(GO:0072010) glomerular visceral epithelial cell differentiation(GO:0072112) glomerular epithelial cell differentiation(GO:0072311)
0.0	0.1	GO:0033023	mast cell homeostasis(GO:0033023) mast cell apoptotic process(GO:0033024) regulation of mast cell apoptotic process(GO:0033025)
0.0	0.1	GO:0042487	regulation of odontogenesis of dentin-containing tooth(GO:0042487)
0.0	0.0	GO:0045578	negative regulation of B cell differentiation(GO:0045578)
0.0	0.1	GO:0042732	D-xylose metabolic process(GO:0042732)
0.0	0.0	GO:0002689	negative regulation of leukocyte chemotaxis(GO:0002689)
0.0	0.1	GO:0006930	substrate-dependent cell migration, cell extension(GO:0006930)
0.0	0.2	GO:0002040	sprouting angiogenesis(GO:0002040)
0.0	0.4	GO:0030199	collagen fibril organization(GO:0030199)
0.0	0.1	GO:0022617	extracellular matrix disassembly(GO:0022617)
0.0	0.0	GO:0061072	iris morphogenesis(GO:0061072)
0.0	0.0	GO:0060872	semicircular canal development(GO:0060872)
0.0	0.0	GO:0046826	negative regulation of protein export from nucleus(GO:0046826)
0.0	0.3	GO:0048286	lung alveolus development(GO:0048286)
0.0	0.0	GO:0048791	calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.0	0.1	GO:0045091	regulation of single stranded viral RNA replication via double stranded DNA intermediate(GO:0045091)
0.0	0.1	GO:0030579	ubiquitin-dependent SMAD protein catabolic process(GO:0030579)
0.0	0.1	GO:0045905	translational frameshifting(GO:0006452) positive regulation of translational elongation(GO:0045901) positive regulation of translational termination(GO:0045905)
0.0	0.1	GO:0007598	blood coagulation, extrinsic pathway(GO:0007598)
0.0	0.1	GO:0031269	pseudopodium assembly(GO:0031269) regulation of pseudopodium assembly(GO:0031272) positive regulation of pseudopodium assembly(GO:0031274)
0.0	0.1	GO:0060014	granulosa cell differentiation(GO:0060014)
0.0	0.1	GO:0033197	response to vitamin E(GO:0033197)
0.0	0.1	GO:0031536	positive regulation of exit from mitosis(GO:0031536)
0.0	0.1	GO:0006667	sphinganine metabolic process(GO:0006667)
0.0	0.2	GO:1903846	positive regulation of transforming growth factor beta receptor signaling pathway(GO:0030511) positive regulation of cellular response to transforming growth factor beta stimulus(GO:1903846)
0.0	0.1	GO:0009648	photoperiodism(GO:0009648)
0.0	0.1	GO:0001547	antral ovarian follicle growth(GO:0001547)
0.0	0.0	GO:0007021	tubulin complex assembly(GO:0007021)
0.0	0.2	GO:0009629	response to gravity(GO:0009629)
0.0	0.0	GO:0014912	negative regulation of smooth muscle cell migration(GO:0014912)
0.0	0.1	GO:0017000	antibiotic metabolic process(GO:0016999) antibiotic biosynthetic process(GO:0017000)
0.0	0.0	GO:0070254	mucus secretion(GO:0070254)
0.0	0.1	GO:0042819	pyridoxine metabolic process(GO:0008614) pyridoxine biosynthetic process(GO:0008615) vitamin B6 metabolic process(GO:0042816) vitamin B6 biosynthetic process(GO:0042819)
0.0	0.1	GO:0070102	interleukin-6-mediated signaling pathway(GO:0070102)
0.0	0.1	GO:0060390	regulation of SMAD protein import into nucleus(GO:0060390)
0.0	0.0	GO:0051547	regulation of keratinocyte migration(GO:0051547) positive regulation of keratinocyte migration(GO:0051549)
0.0	0.1	GO:0060710	chorio-allantoic fusion(GO:0060710)
0.0	0.1	GO:0006590	thyroid hormone generation(GO:0006590)
0.0	0.0	GO:0014848	urinary tract smooth muscle contraction(GO:0014848)
0.0	0.1	GO:0050774	negative regulation of dendrite morphogenesis(GO:0050774)
0.0	0.2	GO:0007567	parturition(GO:0007567)
0.0	0.1	GO:0032236	obsolete positive regulation of calcium ion transport via store-operated calcium channel activity(GO:0032236)
0.0	0.1	GO:0033327	Leydig cell differentiation(GO:0033327)
0.0	0.2	GO:0032964	collagen biosynthetic process(GO:0032964)
0.0	0.1	GO:0009296	obsolete flagellum assembly(GO:0009296)
0.0	0.0	GO:0070427	nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070427)
0.0	0.1	GO:0030321	transepithelial chloride transport(GO:0030321)
0.0	0.0	GO:0090073	positive regulation of protein homodimerization activity(GO:0090073)
0.0	0.1	GO:0032525	somite rostral/caudal axis specification(GO:0032525)
0.0	0.1	GO:0006106	fumarate metabolic process(GO:0006106)
0.0	0.0	GO:0045906	negative regulation of vasoconstriction(GO:0045906)
0.0	0.1	GO:0090084	negative regulation of inclusion body assembly(GO:0090084)
0.0	0.1	GO:0046549	retinal cone cell differentiation(GO:0042670) retinal cone cell development(GO:0046549)
0.0	0.1	GO:0051898	negative regulation of protein kinase B signaling(GO:0051898)
0.0	0.0	GO:0034135	regulation of toll-like receptor 2 signaling pathway(GO:0034135)
0.0	0.1	GO:0060040	retinal bipolar neuron differentiation(GO:0060040)
0.0	0.2	GO:0002026	regulation of the force of heart contraction(GO:0002026)
0.0	0.0	GO:0010719	negative regulation of epithelial to mesenchymal transition(GO:0010719)
0.0	0.1	GO:0042693	muscle cell fate commitment(GO:0042693)
0.0	0.1	GO:0008049	male courtship behavior(GO:0008049)
0.0	0.1	GO:0090273	regulation of somatostatin secretion(GO:0090273)
0.0	0.0	GO:0048853	forebrain morphogenesis(GO:0048853)
0.0	0.1	GO:0070295	renal water absorption(GO:0070295)
0.0	0.1	GO:0043569	negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569)
0.0	0.0	GO:0060999	positive regulation of dendritic spine development(GO:0060999)
0.0	0.1	GO:0045627	positive regulation of T-helper 1 cell differentiation(GO:0045627)
0.0	0.1	GO:0034720	histone H3-K4 demethylation(GO:0034720)
0.0	0.0	GO:0048003	antigen processing and presentation of lipid antigen via MHC class Ib(GO:0048003)
0.0	0.1	GO:0016246	RNA interference(GO:0016246)
0.0	0.1	GO:0031641	regulation of myelination(GO:0031641)
0.0	0.2	GO:0008045	motor neuron axon guidance(GO:0008045)
0.0	0.1	GO:0031000	response to caffeine(GO:0031000)
0.0	0.0	GO:0044240	multicellular organism lipid catabolic process(GO:0044240)
0.0	0.0	GO:0046882	negative regulation of follicle-stimulating hormone secretion(GO:0046882)
0.0	0.0	GO:0033148	positive regulation of intracellular estrogen receptor signaling pathway(GO:0033148)
0.0	0.0	GO:0048643	positive regulation of skeletal muscle tissue development(GO:0048643)
0.0	0.0	GO:0046021	regulation of transcription from RNA polymerase II promoter, mitotic(GO:0046021) positive regulation of transcription from RNA polymerase II promoter during mitosis(GO:0046022)
0.0	0.1	GO:0010765	positive regulation of sodium ion transport(GO:0010765)
0.0	0.1	GO:0000301	retrograde transport, vesicle recycling within Golgi(GO:0000301)
0.0	0.0	GO:0010980	regulation of vitamin D 24-hydroxylase activity(GO:0010979) positive regulation of vitamin D 24-hydroxylase activity(GO:0010980)
0.0	0.1	GO:0045600	positive regulation of fat cell differentiation(GO:0045600)
0.0	0.0	GO:0003170	heart valve development(GO:0003170) heart valve morphogenesis(GO:0003179)
0.0	0.1	GO:0007494	midgut development(GO:0007494)
0.0	0.1	GO:0071028	RNA surveillance(GO:0071025) nuclear RNA surveillance(GO:0071027) nuclear mRNA surveillance(GO:0071028)
0.0	0.0	GO:0046886	positive regulation of hormone metabolic process(GO:0032352) positive regulation of hormone biosynthetic process(GO:0046886)
0.0	0.0	GO:0051451	myoblast migration(GO:0051451)
0.0	0.1	GO:0006448	regulation of translational elongation(GO:0006448)
0.0	0.1	GO:0044314	protein K27-linked ubiquitination(GO:0044314)
0.0	0.1	GO:0007603	phototransduction, visible light(GO:0007603)
0.0	0.0	GO:0003097	renal water transport(GO:0003097)
0.0	0.0	GO:0051481	negative regulation of cytosolic calcium ion concentration(GO:0051481)
0.0	0.3	GO:0030574	collagen catabolic process(GO:0030574)
0.0	0.1	GO:0032288	myelin assembly(GO:0032288)
0.0	0.0	GO:0001778	plasma membrane repair(GO:0001778)
0.0	0.0	GO:0010507	negative regulation of autophagy(GO:0010507)
0.0	0.0	GO:0016199	axon midline choice point recognition(GO:0016199)
0.0	0.2	GO:0006942	regulation of striated muscle contraction(GO:0006942)
0.0	0.1	GO:0043985	histone H4-R3 methylation(GO:0043985)
0.0	0.0	GO:0006591	ornithine metabolic process(GO:0006591)
0.0	0.0	GO:0060638	mesenchymal-epithelial cell signaling(GO:0060638)
0.0	0.0	GO:0042501	serine phosphorylation of STAT protein(GO:0042501)
0.0	0.0	GO:0048867	stem cell fate commitment(GO:0048865) stem cell fate determination(GO:0048867)
0.0	0.0	GO:0032823	regulation of natural killer cell differentiation(GO:0032823) positive regulation of natural killer cell differentiation(GO:0032825)
0.0	0.1	GO:0045880	positive regulation of smoothened signaling pathway(GO:0045880)
0.0	0.1	GO:0006534	cysteine metabolic process(GO:0006534)
0.0	0.2	GO:0048384	retinoic acid receptor signaling pathway(GO:0048384)
0.0	0.1	GO:0007095	mitotic G2 DNA damage checkpoint(GO:0007095)
0.0	0.1	GO:0060259	regulation of feeding behavior(GO:0060259)
0.0	0.3	GO:0010811	positive regulation of cell-substrate adhesion(GO:0010811)
0.0	0.0	GO:0030952	establishment or maintenance of cytoskeleton polarity(GO:0030952)
0.0	0.0	GO:0016080	synaptic vesicle targeting(GO:0016080)
0.0	0.0	GO:0016139	glycoside metabolic process(GO:0016137) glycoside catabolic process(GO:0016139)
0.0	0.0	GO:0051151	negative regulation of smooth muscle cell differentiation(GO:0051151)
0.0	0.1	GO:0006895	Golgi to endosome transport(GO:0006895) Golgi to vacuole transport(GO:0006896)
0.0	0.1	GO:0042253	granulocyte macrophage colony-stimulating factor biosynthetic process(GO:0042253)
0.0	0.1	GO:0045885	obsolete positive regulation of survival gene product expression(GO:0045885)
0.0	0.1	GO:0051482	positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway(GO:0051482)
0.0	0.0	GO:0001574	ganglioside biosynthetic process(GO:0001574)
0.0	0.0	GO:0045792	negative regulation of cell size(GO:0045792)
0.0	0.1	GO:0033235	positive regulation of protein sumoylation(GO:0033235)
0.0	0.1	GO:0006069	ethanol metabolic process(GO:0006067) ethanol oxidation(GO:0006069)
0.0	0.1	GO:0032780	negative regulation of ATPase activity(GO:0032780)
0.0	0.1	GO:0009404	toxin metabolic process(GO:0009404)
0.0	0.0	GO:0043276	anoikis(GO:0043276)
0.0	0.1	GO:0007274	neuromuscular synaptic transmission(GO:0007274)
0.0	0.1	GO:0051818	disruption of cells of other organism involved in symbiotic interaction(GO:0051818) killing of cells in other organism involved in symbiotic interaction(GO:0051883)
0.0	0.1	GO:0090136	epithelial cell-cell adhesion(GO:0090136)
0.0	0.0	GO:0010193	response to ozone(GO:0010193)
0.0	0.0	GO:0030091	protein repair(GO:0030091)
0.0	0.1	GO:0050922	negative regulation of chemotaxis(GO:0050922)
0.0	0.0	GO:0034638	phosphatidylcholine catabolic process(GO:0034638)
0.0	0.0	GO:0051771	negative regulation of nitric-oxide synthase biosynthetic process(GO:0051771)
0.0	0.0	GO:0048861	leukemia inhibitory factor signaling pathway(GO:0048861)
0.0	0.0	GO:0000101	sulfur amino acid transport(GO:0000101) L-cystine transport(GO:0015811)
0.0	0.0	GO:0060023	soft palate development(GO:0060023)
0.0	0.1	GO:0006776	vitamin A metabolic process(GO:0006776)
0.0	0.0	GO:0046083	adenine salvage(GO:0006168) purine nucleobase salvage(GO:0043096) adenine metabolic process(GO:0046083) adenine biosynthetic process(GO:0046084)
0.0	0.0	GO:0072385	minus-end-directed organelle transport along microtubule(GO:0072385)
0.0	0.1	GO:0051096	positive regulation of helicase activity(GO:0051096)
0.0	0.2	GO:0045104	intermediate filament cytoskeleton organization(GO:0045104)
0.0	0.0	GO:0002076	osteoblast development(GO:0002076)
0.0	0.0	GO:0031117	positive regulation of microtubule depolymerization(GO:0031117)
0.0	0.1	GO:0014050	negative regulation of glutamate secretion(GO:0014050)
0.0	0.1	GO:0070189	kynurenine metabolic process(GO:0070189)
0.0	0.1	GO:0051927	obsolete negative regulation of calcium ion transport via voltage-gated calcium channel activity(GO:0051927)
0.0	0.0	GO:0006564	L-serine biosynthetic process(GO:0006564)
0.0	0.0	GO:0090116	DNA methylation on cytosine(GO:0032776) C-5 methylation of cytosine(GO:0090116)
0.0	0.1	GO:0015871	choline transport(GO:0015871)
0.0	0.0	GO:0032650	regulation of interleukin-1 alpha production(GO:0032650) positive regulation of interleukin-1 alpha production(GO:0032730)
0.0	0.0	GO:2000300	regulation of synaptic vesicle transport(GO:1902803) regulation of synaptic vesicle exocytosis(GO:2000300)
0.0	0.0	GO:0043983	histone H4-K12 acetylation(GO:0043983)
0.0	0.0	GO:0030432	peristalsis(GO:0030432)
0.0	0.0	GO:0006654	phosphatidic acid biosynthetic process(GO:0006654)
0.0	0.0	GO:0021591	ventricular system development(GO:0021591)
0.0	0.0	GO:0002025	vasodilation by norepinephrine-epinephrine involved in regulation of systemic arterial blood pressure(GO:0002025)
0.0	0.2	GO:0048010	vascular endothelial growth factor receptor signaling pathway(GO:0048010)
0.0	0.1	GO:0090559	regulation of mitochondrial membrane permeability(GO:0046902) regulation of membrane permeability(GO:0090559)
0.0	0.0	GO:0042268	regulation of cytolysis(GO:0042268)
0.0	0.1	GO:0006646	phosphatidylethanolamine biosynthetic process(GO:0006646) phosphatidylethanolamine metabolic process(GO:0046337)
0.0	0.0	GO:0048148	behavioral response to cocaine(GO:0048148)
0.0	0.0	GO:0000710	meiotic mismatch repair(GO:0000710)
0.0	0.3	GO:0046134	pyrimidine nucleoside biosynthetic process(GO:0046134)
0.0	0.0	GO:0060068	female genitalia morphogenesis(GO:0048807) vagina development(GO:0060068)
0.0	0.0	GO:0043497	regulation of protein heterodimerization activity(GO:0043497)
0.0	0.1	GO:0009396	folic acid-containing compound biosynthetic process(GO:0009396)
0.0	0.0	GO:0030538	embryonic genitalia morphogenesis(GO:0030538)
0.0	0.0	GO:0046838	phosphorylated carbohydrate dephosphorylation(GO:0046838) inositol phosphate dephosphorylation(GO:0046855)
0.0	0.0	GO:0015793	glycerol transport(GO:0015793)
0.0	0.2	GO:0007566	embryo implantation(GO:0007566)
0.0	0.1	GO:0018027	peptidyl-lysine dimethylation(GO:0018027)
0.0	0.1	GO:0019369	arachidonic acid metabolic process(GO:0019369)
0.0	0.0	GO:0019695	choline metabolic process(GO:0019695)
0.0	0.0	GO:0003010	voluntary skeletal muscle contraction(GO:0003010) twitch skeletal muscle contraction(GO:0014721)
0.0	0.0	GO:0030388	fructose 1,6-bisphosphate metabolic process(GO:0030388)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.3	GO:0030934	anchoring collagen complex(GO:0030934)
0.1	0.2	GO:0032059	bleb(GO:0032059)
0.1	0.1	GO:0030132	clathrin coat of coated pit(GO:0030132)
0.0	0.2	GO:0030056	hemidesmosome(GO:0030056)
0.0	0.3	GO:0002102	podosome(GO:0002102)
0.0	0.3	GO:0098645	network-forming collagen trimer(GO:0098642) collagen network(GO:0098645)
0.0	0.1	GO:0005899	insulin receptor complex(GO:0005899)
0.0	0.0	GO:0005862	muscle thin filament tropomyosin(GO:0005862)
0.0	0.3	GO:0030128	AP-2 adaptor complex(GO:0030122) clathrin coat of endocytic vesicle(GO:0030128)
0.0	0.1	GO:0005945	6-phosphofructokinase complex(GO:0005945)
0.0	0.2	GO:0016342	catenin complex(GO:0016342)
0.0	0.1	GO:0016327	apicolateral plasma membrane(GO:0016327)
0.0	0.1	GO:0043260	laminin-11 complex(GO:0043260)
0.0	0.1	GO:0033018	sarcoplasmic reticulum lumen(GO:0033018)
0.0	0.1	GO:0031092	platelet alpha granule membrane(GO:0031092)
0.0	0.1	GO:0042405	nuclear inclusion body(GO:0042405)
0.0	0.2	GO:0005861	troponin complex(GO:0005861)
0.0	0.1	GO:0005588	collagen type V trimer(GO:0005588)
0.0	0.2	GO:0005614	interstitial matrix(GO:0005614)
0.0	0.6	GO:0001725	stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.0	0.4	GO:0009925	basal plasma membrane(GO:0009925)
0.0	0.2	GO:0017146	NMDA selective glutamate receptor complex(GO:0017146)
0.0	0.1	GO:0001527	microfibril(GO:0001527)
0.0	0.4	GO:0030057	desmosome(GO:0030057)
0.0	0.1	GO:0043625	delta DNA polymerase complex(GO:0043625)
0.0	0.2	GO:0000780	condensed nuclear chromosome, centromeric region(GO:0000780)
0.0	0.0	GO:0043083	synaptic cleft(GO:0043083)
0.0	0.1	GO:0005828	kinetochore microtubule(GO:0005828)
0.0	0.1	GO:0046540	U4/U6 x U5 tri-snRNP complex(GO:0046540) spliceosomal tri-snRNP complex(GO:0097526)
0.0	0.1	GO:0042622	photoreceptor outer segment membrane(GO:0042622)
0.0	0.2	GO:0031233	intrinsic component of external side of plasma membrane(GO:0031233)
0.0	1.0	GO:0030496	midbody(GO:0030496)
0.0	0.1	GO:0051233	spindle midzone(GO:0051233)
0.0	0.1	GO:0031588	nucleotide-activated protein kinase complex(GO:0031588)
0.0	0.1	GO:0005896	interleukin-6 receptor complex(GO:0005896)
0.0	0.1	GO:0005581	collagen trimer(GO:0005581)
0.0	0.0	GO:0071062	alphav-beta3 integrin-vitronectin complex(GO:0071062)
0.0	0.1	GO:0071546	pi-body(GO:0071546)
0.0	0.0	GO:0032449	CBM complex(GO:0032449)
0.0	0.1	GO:0031143	pseudopodium(GO:0031143)
0.0	0.0	GO:0070044	synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044)
0.0	0.0	GO:0000176	nuclear exosome (RNase complex)(GO:0000176)
0.0	0.0	GO:0071664	catenin-TCF7L2 complex(GO:0071664)
0.0	0.1	GO:0030688	preribosome, small subunit precursor(GO:0030688)
0.0	0.4	GO:0008305	integrin complex(GO:0008305) protein complex involved in cell adhesion(GO:0098636)
0.0	0.0	GO:0070852	cell body fiber(GO:0070852)
0.0	0.1	GO:0014704	intercalated disc(GO:0014704) cell-cell contact zone(GO:0044291)
0.0	0.0	GO:0005686	U2 snRNP(GO:0005686)
0.0	0.2	GO:0005913	cell-cell adherens junction(GO:0005913)
0.0	0.1	GO:0033180	proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.0	0.4	GO:0030018	Z disc(GO:0030018)
0.0	0.5	GO:0016459	myosin complex(GO:0016459)
0.0	0.3	GO:0030140	trans-Golgi network transport vesicle(GO:0030140)
0.0	0.1	GO:0098643	fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.0	0.1	GO:0043202	lysosomal lumen(GO:0043202)
0.0	0.0	GO:0043230	extracellular organelle(GO:0043230) extracellular exosome(GO:0070062) extracellular vesicle(GO:1903561)
0.0	3.1	GO:0005578	proteinaceous extracellular matrix(GO:0005578)
0.0	0.1	GO:0001917	photoreceptor inner segment(GO:0001917)
0.0	0.1	GO:0031941	filamentous actin(GO:0031941)
0.0	0.0	GO:0035145	exon-exon junction complex(GO:0035145)
0.0	0.0	GO:0005638	lamin filament(GO:0005638)
0.0	0.3	GO:0030665	clathrin-coated vesicle membrane(GO:0030665)
0.0	0.1	GO:0005666	DNA-directed RNA polymerase III complex(GO:0005666)
0.0	0.2	GO:0019861	obsolete flagellum(GO:0019861)
0.0	0.6	GO:0030016	myofibril(GO:0030016)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.6	GO:0017154	semaphorin receptor activity(GO:0017154)
0.1	0.3	GO:0019834	phospholipase A2 inhibitor activity(GO:0019834)
0.1	0.3	GO:0051371	muscle alpha-actinin binding(GO:0051371)
0.1	0.2	GO:0030215	semaphorin receptor binding(GO:0030215)
0.1	0.3	GO:0001099	basal transcription machinery binding(GO:0001098) basal RNA polymerase II transcription machinery binding(GO:0001099)
0.1	0.3	GO:0015016	[heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
0.1	0.3	GO:0010314	phosphatidylinositol-5-phosphate binding(GO:0010314)
0.1	0.2	GO:0003680	AT DNA binding(GO:0003680)
0.1	0.4	GO:0003708	retinoic acid receptor activity(GO:0003708)
0.1	0.2	GO:0004800	thyroxine 5'-deiodinase activity(GO:0004800)
0.0	0.3	GO:0017166	vinculin binding(GO:0017166)
0.0	0.1	GO:0042799	histone methyltransferase activity (H4-K20 specific)(GO:0042799)
0.0	0.2	GO:0016934	extracellular-glycine-gated ion channel activity(GO:0016933) extracellular-glycine-gated chloride channel activity(GO:0016934)
0.0	0.1	GO:0004117	calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117)
0.0	0.1	GO:0050501	hyaluronan synthase activity(GO:0050501)
0.0	0.1	GO:0043515	kinetochore binding(GO:0043515)
0.0	0.1	GO:0050508	glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0050508)
0.0	0.2	GO:0042805	actinin binding(GO:0042805)
0.0	0.1	GO:0004013	adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.0	0.1	GO:0016623	oxidoreductase activity, acting on the aldehyde or oxo group of donors, oxygen as acceptor(GO:0016623)
0.0	0.1	GO:0002162	dystroglycan binding(GO:0002162)
0.0	0.1	GO:0005006	epidermal growth factor-activated receptor activity(GO:0005006)
0.0	0.1	GO:0042808	obsolete neuronal Cdc2-like kinase binding(GO:0042808)
0.0	0.1	GO:0035514	DNA demethylase activity(GO:0035514) DNA-N1-methyladenine dioxygenase activity(GO:0043734)
0.0	0.1	GO:0050693	LBD domain binding(GO:0050693)
0.0	0.2	GO:0030297	transmembrane receptor protein tyrosine kinase activator activity(GO:0030297)
0.0	0.1	GO:0050431	transforming growth factor beta binding(GO:0050431)
0.0	0.1	GO:0033130	acetylcholine receptor binding(GO:0033130)
0.0	0.2	GO:0070063	RNA polymerase binding(GO:0070063)
0.0	0.2	GO:0004028	3-chloroallyl aldehyde dehydrogenase activity(GO:0004028)
0.0	0.5	GO:0005523	tropomyosin binding(GO:0005523)
0.0	0.1	GO:0005030	neurotrophin receptor activity(GO:0005030)
0.0	0.1	GO:0016941	natriuretic peptide receptor activity(GO:0016941)
0.0	0.0	GO:0070052	collagen V binding(GO:0070052)
0.0	0.2	GO:0043237	laminin-1 binding(GO:0043237)
0.0	0.1	GO:0050220	prostaglandin-E synthase activity(GO:0050220)
0.0	0.7	GO:0050840	extracellular matrix binding(GO:0050840)
0.0	0.1	GO:0004720	protein-lysine 6-oxidase activity(GO:0004720)
0.0	0.2	GO:0005021	vascular endothelial growth factor-activated receptor activity(GO:0005021)
0.0	0.1	GO:0017112	Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0	0.1	GO:0048185	activin binding(GO:0048185)
0.0	0.1	GO:0003872	6-phosphofructokinase activity(GO:0003872)
0.0	0.1	GO:0055103	ligase regulator activity(GO:0055103) ubiquitin-protein transferase regulator activity(GO:0055106)
0.0	0.1	GO:0017159	pantetheine hydrolase activity(GO:0017159)
0.0	0.1	GO:0042156	obsolete zinc-mediated transcriptional activator activity(GO:0042156)
0.0	0.1	GO:0005148	prolactin receptor binding(GO:0005148)
0.0	0.1	GO:0042285	UDP-xylosyltransferase activity(GO:0035252) xylosyltransferase activity(GO:0042285)
0.0	0.1	GO:0015183	L-aspartate transmembrane transporter activity(GO:0015183)
0.0	0.1	GO:0001601	peptide YY receptor activity(GO:0001601)
0.0	0.1	GO:0004758	serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
0.0	0.2	GO:0042153	obsolete RPTP-like protein binding(GO:0042153)
0.0	0.2	GO:0004859	phospholipase inhibitor activity(GO:0004859)
0.0	0.1	GO:0001515	opioid peptide activity(GO:0001515)
0.0	0.1	GO:0033765	steroid dehydrogenase activity, acting on the CH-CH group of donors(GO:0033765)
0.0	0.2	GO:0004499	N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.0	0.1	GO:0002060	purine nucleobase binding(GO:0002060)
0.0	0.2	GO:0070402	NADPH binding(GO:0070402)
0.0	0.3	GO:0043498	obsolete cell surface binding(GO:0043498)
0.0	0.2	GO:0030371	translation repressor activity(GO:0030371)
0.0	0.1	GO:0001758	retinal dehydrogenase activity(GO:0001758)
0.0	0.1	GO:0047499	calcium-independent phospholipase A2 activity(GO:0047499)
0.0	0.1	GO:0008327	methyl-CpG binding(GO:0008327)
0.0	0.2	GO:0048407	platelet-derived growth factor binding(GO:0048407)
0.0	0.0	GO:0043184	vascular endothelial growth factor receptor 2 binding(GO:0043184)
0.0	0.1	GO:0045236	CXCR chemokine receptor binding(GO:0045236)
0.0	0.1	GO:0004937	alpha1-adrenergic receptor activity(GO:0004937)
0.0	0.1	GO:0045499	chemorepellent activity(GO:0045499)
0.0	0.1	GO:0031545	procollagen-proline 4-dioxygenase activity(GO:0004656) peptidyl-proline 4-dioxygenase activity(GO:0031545)
0.0	0.1	GO:0030020	extracellular matrix structural constituent conferring tensile strength(GO:0030020)
0.0	0.1	GO:0004687	myosin light chain kinase activity(GO:0004687)
0.0	0.1	GO:0044020	histone methyltransferase activity (H4-R3 specific)(GO:0044020)
0.0	0.1	GO:0004924	oncostatin-M receptor activity(GO:0004924)
0.0	0.2	GO:0008271	secondary active sulfate transmembrane transporter activity(GO:0008271)
0.0	0.1	GO:0015065	uridine nucleotide receptor activity(GO:0015065) G-protein coupled pyrimidinergic nucleotide receptor activity(GO:0071553)
0.0	0.1	GO:0004948	calcitonin receptor activity(GO:0004948)
0.0	0.0	GO:0048018	receptor agonist activity(GO:0048018)
0.0	0.1	GO:0008046	axon guidance receptor activity(GO:0008046)
0.0	0.1	GO:0001591	dopamine neurotransmitter receptor activity, coupled via Gi/Go(GO:0001591)
0.0	0.1	GO:0034186	apolipoprotein A-I binding(GO:0034186)
0.0	0.1	GO:0008294	calcium- and calmodulin-responsive adenylate cyclase activity(GO:0008294)
0.0	0.2	GO:0016813	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
0.0	0.3	GO:0005024	transforming growth factor beta-activated receptor activity(GO:0005024)
0.0	0.1	GO:0004694	eukaryotic translation initiation factor 2alpha kinase activity(GO:0004694)
0.0	0.2	GO:0005112	Notch binding(GO:0005112)
0.0	0.1	GO:0004470	malic enzyme activity(GO:0004470)
0.0	0.1	GO:0046965	retinoid X receptor binding(GO:0046965)
0.0	0.1	GO:0042910	xenobiotic-transporting ATPase activity(GO:0008559) xenobiotic transporter activity(GO:0042910)
0.0	0.1	GO:0047498	calcium-dependent phospholipase A2 activity(GO:0047498)
0.0	0.1	GO:0036137	kynurenine-oxoglutarate transaminase activity(GO:0016212) kynurenine aminotransferase activity(GO:0036137)
0.0	0.1	GO:0008475	procollagen-lysine 5-dioxygenase activity(GO:0008475)
0.0	0.1	GO:0031821	G-protein coupled serotonin receptor binding(GO:0031821)
0.0	0.1	GO:0004862	cAMP-dependent protein kinase inhibitor activity(GO:0004862)
0.0	0.1	GO:0070696	transmembrane receptor protein serine/threonine kinase binding(GO:0070696)
0.0	0.1	GO:0004024	alcohol dehydrogenase activity, zinc-dependent(GO:0004024)
0.0	0.1	GO:0047115	trans-1,2-dihydrobenzene-1,2-diol dehydrogenase activity(GO:0047115)
0.0	0.1	GO:0005042	netrin receptor activity(GO:0005042)
0.0	0.1	GO:0030274	LIM domain binding(GO:0030274)
0.0	0.1	GO:0044390	ubiquitin conjugating enzyme binding(GO:0031624) ubiquitin-like protein conjugating enzyme binding(GO:0044390)
0.0	0.1	GO:0047372	acylglycerol lipase activity(GO:0047372)
0.0	0.1	GO:0031994	insulin-like growth factor I binding(GO:0031994)
0.0	0.1	GO:0015254	glycerol channel activity(GO:0015254)
0.0	0.0	GO:0047045	testosterone 17-beta-dehydrogenase (NADP+) activity(GO:0047045)
0.0	0.1	GO:0008253	5'-nucleotidase activity(GO:0008253)
0.0	0.1	GO:0034648	histone demethylase activity (H3-K4 specific)(GO:0032453) histone demethylase activity (H3-dimethyl-K4 specific)(GO:0034648)
0.0	0.1	GO:0005152	interleukin-1 receptor antagonist activity(GO:0005152)
0.0	0.0	GO:0003876	AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.0	0.1	GO:0008312	7S RNA binding(GO:0008312)
0.0	0.0	GO:0005173	stem cell factor receptor binding(GO:0005173)
0.0	0.0	GO:0004607	phosphatidylcholine-sterol O-acyltransferase activity(GO:0004607)
0.0	0.1	GO:0016847	1-aminocyclopropane-1-carboxylate synthase activity(GO:0016847)
0.0	0.1	GO:0005110	frizzled-2 binding(GO:0005110)
0.0	0.3	GO:0031683	G-protein beta/gamma-subunit complex binding(GO:0031683)
0.0	0.3	GO:0005001	transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.0	0.0	GO:0016909	JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.0	0.1	GO:0015037	peptide disulfide oxidoreductase activity(GO:0015037)
0.0	0.1	GO:0004597	peptide-aspartate beta-dioxygenase activity(GO:0004597)
0.0	0.1	GO:0048019	receptor antagonist activity(GO:0048019)
0.0	0.0	GO:0003953	NAD+ nucleosidase activity(GO:0003953)
0.0	0.1	GO:0016832	aldehyde-lyase activity(GO:0016832)
0.0	0.1	GO:0004849	uridine kinase activity(GO:0004849)
0.0	0.0	GO:0008607	phosphorylase kinase regulator activity(GO:0008607)
0.0	0.1	GO:0001968	fibronectin binding(GO:0001968)
0.0	0.0	GO:0005010	insulin-like growth factor-activated receptor activity(GO:0005010)
0.0	0.0	GO:0030343	vitamin D3 25-hydroxylase activity(GO:0030343) vitamin D 25-hydroxylase activity(GO:0070643)
0.0	0.1	GO:0005123	death receptor binding(GO:0005123)
0.0	0.1	GO:0019238	cyclohydrolase activity(GO:0019238)
0.0	0.0	GO:0048495	Roundabout binding(GO:0048495)
0.0	0.0	GO:0008331	high voltage-gated calcium channel activity(GO:0008331)
0.0	0.1	GO:0047429	nucleoside-triphosphate diphosphatase activity(GO:0047429)
0.0	0.0	GO:0004992	platelet activating factor receptor activity(GO:0004992)
0.0	0.2	GO:0015269	calcium-activated potassium channel activity(GO:0015269)
0.0	0.0	GO:0004461	lactose synthase activity(GO:0004461)
0.0	0.3	GO:0016769	transferase activity, transferring nitrogenous groups(GO:0016769)
0.0	0.0	GO:0030023	extracellular matrix constituent conferring elasticity(GO:0030023) structural molecule activity conferring elasticity(GO:0097493)
0.0	0.2	GO:0005247	voltage-gated chloride channel activity(GO:0005247)
0.0	0.1	GO:0046790	virion binding(GO:0046790)
0.0	0.1	GO:0032137	guanine/thymine mispair binding(GO:0032137)
0.0	0.6	GO:0004714	transmembrane receptor protein tyrosine kinase activity(GO:0004714)
0.0	0.1	GO:0004305	ethanolamine kinase activity(GO:0004305)
0.0	0.0	GO:0005534	galactose binding(GO:0005534)
0.0	0.2	GO:0035035	histone acetyltransferase binding(GO:0035035)
0.0	0.0	GO:0070996	type 1 melanocortin receptor binding(GO:0070996)
0.0	0.1	GO:0008191	metalloendopeptidase inhibitor activity(GO:0008191)
0.0	0.1	GO:0050656	3'-phosphoadenosine 5'-phosphosulfate binding(GO:0050656)
0.0	0.1	GO:0004128	cytochrome-b5 reductase activity, acting on NAD(P)H(GO:0004128)
0.0	0.1	GO:0000339	RNA cap binding(GO:0000339)
0.0	0.1	GO:0003846	2-acylglycerol O-acyltransferase activity(GO:0003846)
0.0	0.0	GO:0015193	L-proline transmembrane transporter activity(GO:0015193)
0.0	0.0	GO:0005172	vascular endothelial growth factor receptor binding(GO:0005172)
0.0	0.1	GO:0016018	cyclosporin A binding(GO:0016018)
0.0	0.0	GO:0050998	nitric-oxide synthase binding(GO:0050998)
0.0	0.1	GO:0070290	N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.0	0.7	GO:0005201	extracellular matrix structural constituent(GO:0005201)
0.0	0.0	GO:0003886	DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.0	0.1	GO:0022821	potassium ion antiporter activity(GO:0022821)
0.0	0.1	GO:0015220	choline transmembrane transporter activity(GO:0015220)
0.0	0.0	GO:0004351	glutamate decarboxylase activity(GO:0004351)
0.0	0.0	GO:0004515	nicotinamide-nucleotide adenylyltransferase activity(GO:0000309) nicotinate-nucleotide adenylyltransferase activity(GO:0004515)
0.0	0.0	GO:0048027	mRNA 5'-UTR binding(GO:0048027)
0.0	0.1	GO:0070628	proteasome binding(GO:0070628)
0.0	0.0	GO:0004616	phosphogluconate dehydrogenase (decarboxylating) activity(GO:0004616)
0.0	0.1	GO:0015279	store-operated calcium channel activity(GO:0015279)
0.0	0.1	GO:0016500	protein-hormone receptor activity(GO:0016500)
0.0	0.0	GO:0003829	beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity(GO:0003829)
0.0	0.0	GO:0003956	NAD(P)+-protein-arginine ADP-ribosyltransferase activity(GO:0003956)
0.0	0.0	GO:0004032	alditol:NADP+ 1-oxidoreductase activity(GO:0004032)
0.0	0.1	GO:0042800	histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.0	0.2	GO:0008093	cytoskeletal adaptor activity(GO:0008093)
0.0	0.0	GO:0035198	miRNA binding(GO:0035198)
0.0	0.0	GO:0045294	alpha-catenin binding(GO:0045294)
0.0	0.0	GO:0004047	aminomethyltransferase activity(GO:0004047)
0.0	0.1	GO:0010853	cyclase activator activity(GO:0010853) guanylate cyclase activator activity(GO:0030250)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.1	PID GLYPICAN 1PATHWAY	Glypican 1 network
0.1	0.6	PID VEGF VEGFR PATHWAY	VEGF and VEGFR signaling network
0.0	0.0	PID INTEGRIN4 PATHWAY	Alpha6 beta4 integrin-ligand interactions
0.0	0.5	PID INTEGRIN5 PATHWAY	Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.0	0.2	PID LYSOPHOSPHOLIPID PATHWAY	LPA receptor mediated events
0.0	0.0	PID EPHRINB REV PATHWAY	Ephrin B reverse signaling
0.0	0.4	PID ERBB NETWORK PATHWAY	ErbB receptor signaling network
0.0	1.0	NABA COLLAGENS	Genes encoding collagen proteins
0.0	0.0	PID IGF1 PATHWAY	IGF1 pathway
0.0	0.3	PID SYNDECAN 1 PATHWAY	Syndecan-1-mediated signaling events
0.0	0.2	SA G2 AND M PHASES	Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.0	0.1	PID NETRIN PATHWAY	Netrin-mediated signaling events
0.0	0.5	PID RXR VDR PATHWAY	RXR and RAR heterodimerization with other nuclear receptor
0.0	0.0	ST JAK STAT PATHWAY	Jak-STAT Pathway
0.0	0.2	ST G ALPHA S PATHWAY	G alpha s Pathway
0.0	0.0	PID REELIN PATHWAY	Reelin signaling pathway
0.0	0.3	PID INTEGRIN A9B1 PATHWAY	Alpha9 beta1 integrin signaling events
0.0	0.3	PID S1P S1P2 PATHWAY	S1P2 pathway
0.0	0.2	PID LPA4 PATHWAY	LPA4-mediated signaling events
0.0	0.1	PID FOXO PATHWAY	FoxO family signaling
0.0	0.0	PID ECADHERIN KERATINOCYTE PATHWAY	E-cadherin signaling in keratinocytes
0.0	0.5	PID INTEGRIN1 PATHWAY	Beta1 integrin cell surface interactions
0.0	0.5	NABA PROTEOGLYCANS	Genes encoding proteoglycans
0.0	0.7	PID TAP63 PATHWAY	Validated transcriptional targets of TAp63 isoforms
0.0	0.1	SA PROGRAMMED CELL DEATH	Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.0	0.0	PID ER NONGENOMIC PATHWAY	Plasma membrane estrogen receptor signaling
0.0	0.2	PID HEDGEHOG 2PATHWAY	Signaling events mediated by the Hedgehog family
0.0	0.5	PID RHOA REG PATHWAY	Regulation of RhoA activity
0.0	0.1	PID AJDISS 2PATHWAY	Posttranslational regulation of adherens junction stability and dissassembly
0.0	0.3	PID WNT SIGNALING PATHWAY	Wnt signaling network
0.0	0.2	PID SYNDECAN 2 PATHWAY	Syndecan-2-mediated signaling events
0.0	0.2	PID UPA UPAR PATHWAY	Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.0	0.4	PID HNF3A PATHWAY	FOXA1 transcription factor network
0.0	0.0	SA G1 AND S PHASES	Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition.

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.7	REACTOME VEGF LIGAND RECEPTOR INTERACTIONS	Genes involved in VEGF ligand-receptor interactions
0.1	0.1	REACTOME PECAM1 INTERACTIONS	Genes involved in PECAM1 interactions
0.0	0.0	REACTOME G ALPHA Z SIGNALLING EVENTS	Genes involved in G alpha (z) signalling events
0.0	0.1	REACTOME ADP SIGNALLING THROUGH P2RY12	Genes involved in ADP signalling through P2Y purinoceptor 12
0.0	0.1	REACTOME SIGNALING BY CONSTITUTIVELY ACTIVE EGFR	Genes involved in Signaling by constitutively active EGFR
0.0	0.5	REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS	Genes involved in Cell-extracellular matrix interactions
0.0	0.8	REACTOME SMOOTH MUSCLE CONTRACTION	Genes involved in Smooth Muscle Contraction
0.0	0.0	REACTOME SIGNALING BY ILS	Genes involved in Signaling by Interleukins
0.0	0.2	REACTOME RETROGRADE NEUROTROPHIN SIGNALLING	Genes involved in Retrograde neurotrophin signalling
0.0	0.0	REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS	Genes involved in Synthesis of bile acids and bile salts
0.0	0.7	REACTOME MYOGENESIS	Genes involved in Myogenesis
0.0	0.0	REACTOME RNA POL I PROMOTER OPENING	Genes involved in RNA Polymerase I Promoter Opening
0.0	0.3	REACTOME ADENYLATE CYCLASE INHIBITORY PATHWAY	Genes involved in Adenylate cyclase inhibitory pathway
0.0	0.1	REACTOME INFLUENZA VIRAL RNA TRANSCRIPTION AND REPLICATION	Genes involved in Influenza Viral RNA Transcription and Replication
0.0	0.2	REACTOME ETHANOL OXIDATION	Genes involved in Ethanol oxidation
0.0	0.7	REACTOME HS GAG BIOSYNTHESIS	Genes involved in HS-GAG biosynthesis
0.0	0.3	REACTOME OTHER SEMAPHORIN INTERACTIONS	Genes involved in Other semaphorin interactions
0.0	0.2	REACTOME GAP JUNCTION DEGRADATION	Genes involved in Gap junction degradation
0.0	0.2	REACTOME TRYPTOPHAN CATABOLISM	Genes involved in Tryptophan catabolism
0.0	1.0	REACTOME COLLAGEN FORMATION	Genes involved in Collagen formation
0.0	0.2	REACTOME A TETRASACCHARIDE LINKER SEQUENCE IS REQUIRED FOR GAG SYNTHESIS	Genes involved in A tetrasaccharide linker sequence is required for GAG synthesis
0.0	0.0	REACTOME PD1 SIGNALING	Genes involved in PD-1 signaling
0.0	0.1	REACTOME ANDROGEN BIOSYNTHESIS	Genes involved in Androgen biosynthesis
0.0	0.2	REACTOME ACYL CHAIN REMODELLING OF PI	Genes involved in Acyl chain remodelling of PI
0.0	0.3	REACTOME SIGNALING BY BMP	Genes involved in Signaling by BMP
0.0	0.2	REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING	Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.0	0.1	REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR	Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.0	0.1	REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS	Genes involved in Apoptotic cleavage of cell adhesion proteins
0.0	0.3	REACTOME ADHERENS JUNCTIONS INTERACTIONS	Genes involved in Adherens junctions interactions
0.0	0.1	REACTOME SIGNALING BY ACTIVATED POINT MUTANTS OF FGFR1	Genes involved in Signaling by activated point mutants of FGFR1
0.0	0.1	REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN	Genes involved in Platelet Adhesion to exposed collagen
0.0	0.3	REACTOME NCAM1 INTERACTIONS	Genes involved in NCAM1 interactions
0.0	0.2	REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION	Genes involved in Amino acid synthesis and interconversion (transamination)
0.0	0.1	REACTOME SIGNAL ATTENUATION	Genes involved in Signal attenuation
0.0	0.1	REACTOME DCC MEDIATED ATTRACTIVE SIGNALING	Genes involved in DCC mediated attractive signaling
0.0	0.1	REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE	Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.0	0.2	REACTOME PEPTIDE HORMONE BIOSYNTHESIS	Genes involved in Peptide hormone biosynthesis
0.0	0.1	REACTOME PURINE CATABOLISM	Genes involved in Purine catabolism