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ENCODE: H3K4me1 ChIP-Seq of primary human cells
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Results for OTX2_CRX

Z-value: 1.48

Motif logo

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Transcription factors associated with OTX2_CRX

Gene Symbol Gene ID Gene Info
OTX2
ENSG00000165588.12 orthodenticle homeobox 2
CRX
ENSG00000105392.11 cone-rod homeobox

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE Gene Distance Association probability Pearson corr. coef. P-value Plot
chr14_57264264_57264415OTX280270.169813-0.618.2e-02Click!
chr14_57263392_57263543OTX288990.168034-0.561.2e-01Click!
chr14_57262189_57262340OTX2101020.166133-0.472.0e-01Click!
chr14_57274823_57275045OTX222320.254600-0.412.7e-01Click!
chr14_57274493_57274644OTX221870.259421-0.383.2e-01Click!

Activity of the OTX2_CRX motif across conditions

Conditions sorted by the z-value of the OTX2_CRX motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE) Target Score Top associated gene Gene Info Distance of CRE to TSS CRE/Gene association probability
chr2_43152776_43153425 0.71 HAAO
 3-hydroxyanthranilate 3,4-dioxygenase
 133368
 0.05
chr19_47478570_47478952 0.63 ENSG00000252071
 .
 27215
 0.14
chr12_11733022_11733284 0.58 ENSG00000251747
 .
 33740
 0.16
chr1_201426596_201426747 0.56 PHLDA3
 pleckstrin homology-like domain, family A, member 3
 11641
 0.15
chr14_53301825_53302222 0.53 FERMT2
 fermitin family member 2
 29216
 0.15
chr20_34489809_34489960 0.53 ENSG00000201221
 .
 14303
 0.13
chr17_30068402_30068553 0.45 ENSG00000202026
 .
 27705
 0.19
chr15_46162513_46162674 0.45 SQRDL
 sulfide quinone reductase-like (yeast)
 187855
 0.03
chr6_130645263_130645558 0.42 SAMD3
 sterile alpha motif domain containing 3
 41160
 0.17
chr22_27531516_27531667 0.42 ENSG00000200443
 .
 99741
 0.09
chr4_169496141_169496292 0.39 PALLD
 palladin, cytoskeletal associated protein
 56550
 0.12
chr4_122705792_122706078 0.38 EXOSC9
 exosome component 9
 16537
 0.14
chr5_64493902_64494516 0.38 ENSG00000207439
 .
 75013
 0.12
chr4_39525693_39526119 0.38 UGDH
 UDP-glucose 6-dehydrogenase
 2271
 0.25
chr8_12583298_12583449 0.35 ENSG00000266206
 .
 1440
 0.38
chr1_208382716_208382867 0.35 PLXNA2
 plexin A2
 34874
 0.24
chr1_21478340_21478712 0.35 EIF4G3
 eukaryotic translation initiation factor 4 gamma, 3
 22704
 0.19
chr9_16795794_16795945 0.35 BNC2
 basonuclin 2
 36417
 0.21
chr3_170470237_170470470 0.35 ENSG00000222411
 .
 89608
 0.08
chr11_19420172_19420323 0.35 ENSG00000200687
 .
 3281
 0.25
chr11_82690749_82690900 0.35 PRCP
 prolylcarboxypeptidase (angiotensinase C)
 9198
 0.18
chr14_80050698_80050849 0.34 RP11-242P2.2
48881
 0.19
chr14_69544397_69544681 0.34 ENSG00000206768
 .
 66131
 0.1
chr11_19222231_19222783 0.34 CSRP3
 cysteine and glycine-rich protein 3 (cardiac LIM protein)
 1082
 0.5
chr12_1427689_1428011 0.34 RP5-951N9.2
67149
 0.11
chr6_82476723_82477129 0.34 ENSG00000206886
 .
 3185
 0.27
chr5_148352238_148352777 0.34 RP11-44B19.1
2604
 0.3
chr5_81460698_81461288 0.33 ENSG00000265684
 .
 86747
 0.08
chr1_67397953_67399117 0.33 MIER1
 mesoderm induction early response 1, transcriptional regulator
 2609
 0.29
chr17_73690444_73690713 0.33 SAP30BP
 SAP30 binding protein
 1952
 0.18
chr1_86020329_86020665 0.33 DDAH1
 dimethylarginine dimethylaminohydrolase 1
 23436
 0.17
chr5_95004855_95005067 0.32 SPATA9
 spermatogenesis associated 9
 13699
 0.16
chr2_28497749_28498516 0.32 AC093690.1
35194
 0.19
chr5_159305915_159306327 0.32 ADRA1B
 adrenoceptor alpha 1B
 37669
 0.2
chr8_97603049_97603490 0.32 SDC2
 syndecan 2
 4654
 0.31
chr1_171096536_171096687 0.31 FMO6P
 flavin containing monooxygenase 6 pseudogene
 10630
 0.16
chr5_64500241_64500433 0.31 ENSG00000207439
 .
 81141
 0.11
chr1_59481843_59482033 0.31 JUN
 jun proto-oncogene
 232153
 0.02
chr12_110493934_110494306 0.31 C12orf76
 chromosome 12 open reading frame 76
 7030
 0.2
chr5_57134395_57134546 0.31 ENSG00000266864
 .
 34403
 0.24
chr22_36369506_36369746 0.31 RBFOX2
 RNA binding protein, fox-1 homolog (C. elegans) 2
 11912
 0.28
chr2_159996739_159997187 0.31 ENSG00000202029
 .
 113309
 0.06
chr8_119017458_119017609 0.31 EXT1
 exostosin glycosyltransferase 1
 105120
 0.08
chr2_206577775_206577938 0.30 NRP2
 neuropilin 2
 29841
 0.21
chr10_34393778_34393929 0.30 ENSG00000199200
 .
 97149
 0.09
chr10_35021138_35021390 0.30 PARD3
 par-3 family cell polarity regulator
 82985
 0.1
chr19_43493188_43493339 0.30 PSG11
 pregnancy specific beta-1-glycoprotein 11
 37337
 0.15
chr5_34487773_34488055 0.30 RAI14
 retinoic acid induced 14
 168428
 0.03
chr6_35393359_35394053 0.30 FANCE
 Fanconi anemia, complementation group E
 26432
 0.15
chr8_10657129_10657397 0.30 ENSG00000252565
 .
 15698
 0.15
chr6_110417870_110418143 0.30 WASF1
 WAS protein family, member 1
 82846
 0.09
chr9_14271441_14271727 0.29 NFIB
 nuclear factor I/B
 36428
 0.2
chr2_162949372_162949523 0.29 DPP4
 dipeptidyl-peptidase 4
 18395
 0.18
chr11_130642757_130642947 0.29 C11orf44
 chromosome 11 open reading frame 44
 100001
 0.08
chr11_86447090_86447241 0.29 PRSS23
 protease, serine, 23
 54936
 0.15
chr8_37783052_37783203 0.29 GOT1L1
 glutamic-oxaloacetic transaminase 1-like 1
 11204
 0.13
chr9_74299304_74300206 0.29 TMEM2
 transmembrane protein 2
 20093
 0.28
chr18_68088910_68089061 0.28 ENSG00000264059
 .
 59526
 0.13
chr15_35988877_35989028 0.28 DPH6
 diphthamine biosynthesis 6
 150559
 0.05
chr12_13278087_13278467 0.28 GSG1
 germ cell associated 1
 21658
 0.19
chrX_12378398_12378549 0.28 FRMPD4-AS1
 FRMPD4 antisense RNA 1
 14779
 0.29
chr14_69013976_69014127 0.28 CTD-2325P2.4
81111
 0.1
chr16_69098691_69098842 0.28 HAS3
 hyaluronan synthase 3
 40701
 0.11
chr16_66652366_66652517 0.28 CMTM3
 CKLF-like MARVEL transmembrane domain containing 3
 13017
 0.11
chr1_52024489_52024927 0.28 OSBPL9
 oxysterol binding protein-like 9
 18143
 0.15
chr17_66755524_66755734 0.28 ENSG00000263690
 .
 7071
 0.3
chr10_3570543_3570694 0.28 RP11-184A2.3
222641
 0.02
chr9_14251628_14251779 0.28 NFIB
 nuclear factor I/B
 56309
 0.15
chr8_104117274_104117548 0.28 ENSG00000265667
 .
 12462
 0.13
chr2_196440572_196441282 0.28 SLC39A10
 solute carrier family 39 (zinc transporter), member 10
 226
 0.96
chr2_227289868_227290019 0.27 ENSG00000263363
 .
 233566
 0.02
chr12_110388287_110388838 0.27 GIT2
 G protein-coupled receptor kinase interacting ArfGAP 2
 45467
 0.11
chr6_1575312_1575463 0.27 FOXC1
 forkhead box C1
 35294
 0.21
chr5_169180771_169181008 0.27 DOCK2
 dedicator of cytokinesis 2
 5832
 0.26
chr2_43496469_43496754 0.27 AC010883.5
39899
 0.17
chr11_108786966_108787117 0.27 ENSG00000201243
 .
 89203
 0.1
chr5_57032113_57032264 0.27 ENSG00000221195
 .
 93375
 0.09
chr3_124849030_124849181 0.27 SLC12A8
 solute carrier family 12, member 8
 9407
 0.17
chr12_66341786_66341937 0.27 RP11-366L20.3
398
 0.86
chr9_111396759_111396910 0.27 ACTL7B
 actin-like 7B
 222405
 0.02
chr16_11295567_11296301 0.27 RMI2
 RecQ mediated genome instability 2
 47572
 0.08
chr6_38230519_38230766 0.27 ENSG00000200706
 .
 55592
 0.15
chr1_30185013_30185164 0.27 ENSG00000221126
 .
 67563
 0.14
chr1_158029342_158029493 0.27 KIRREL
 kin of IRRE like (Drosophila)
 27053
 0.18
chr2_231481752_231482027 0.27 ENSG00000199791
 .
 30053
 0.17
chr10_131821141_131821577 0.27 EBF3
 early B-cell factor 3
 59254
 0.15
chr3_149469081_149469660 0.27 COMMD2
 COMM domain containing 2
 916
 0.55
chr10_33505911_33506062 0.27 NRP1
 neuropilin 1
 3497
 0.27
chr2_75120069_75120220 0.27 HK2
 hexokinase 2
 57847
 0.12
chr3_174156335_174156660 0.27 NAALADL2
 N-acetylated alpha-linked acidic dipeptidase-like 2
 2280
 0.47
chr17_79532915_79533078 0.27 NPLOC4
 nuclear protein localization 4 homolog (S. cerevisiae)
 632
 0.54
chr9_84173660_84173811 0.27 TLE1
 transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila)
 54702
 0.17
chr2_200274877_200275028 0.26 SATB2
 SATB homeobox 2
 45859
 0.16
chr9_117715769_117716310 0.26 TNFSF8
 tumor necrosis factor (ligand) superfamily, member 8
 23342
 0.24
chr12_53693833_53694662 0.26 RP11-680A11.5
149
 0.73
chr6_43088179_43088500 0.26 PTK7
 protein tyrosine kinase 7
 9990
 0.12
chr1_181047003_181047287 0.26 IER5
 immediate early response 5
 10493
 0.21
chr4_129149985_129150136 0.26 PGRMC2
 progesterone receptor membrane component 2
 44156
 0.2
chr3_111480055_111480487 0.26 PHLDB2
 pleckstrin homology-like domain, family B, member 2
 28927
 0.2
chr15_40289924_40290075 0.26 EIF2AK4
 eukaryotic translation initiation factor 2 alpha kinase 4
 32595
 0.12
chr4_152666058_152666209 0.26 PET112
 PET112 homolog (yeast)
 16004
 0.24
chr2_160816916_160817067 0.26 LY75-CD302
 LY75-CD302 readthrough
 55770
 0.13
chr4_171593437_171593770 0.26 ENSG00000251961
 .
 219015
 0.02
chr12_66262478_66262882 0.26 ENSG00000211577
 .
 10887
 0.18
chr5_39093457_39093608 0.26 AC008964.1
11826
 0.23
chr2_183457874_183458025 0.26 PDE1A
 phosphodiesterase 1A, calmodulin-dependent
 70484
 0.12
chr2_45926277_45926449 0.26 U51244.2
23748
 0.22
chr16_11098719_11098870 0.26 CLEC16A
 C-type lectin domain family 16, member A
 60356
 0.08
chr1_117690204_117690355 0.26 TRIM45
 tripartite motif containing 45
 25070
 0.15
chr1_99922703_99922854 0.26 LPPR4
 Lipid phosphate phosphatase-related protein type 4
 158358
 0.04
chr1_85805501_85805652 0.26 ENSG00000264380
 .
 55283
 0.09
chr11_67979238_67979938 0.26 SUV420H1
 suppressor of variegation 4-20 homolog 1 (Drosophila)
 633
 0.74
chr4_77956814_77956965 0.25 SEPT11
 septin 11
 7019
 0.23
chr15_99994749_99995202 0.25 MEF2A
 myocyte enhancer factor 2A
 22395
 0.18
chr6_3517760_3517987 0.25 SLC22A23
 solute carrier family 22, member 23
 60617
 0.14
chr1_223584357_223584508 0.25 C1orf65
 chromosome 1 open reading frame 65
 17717
 0.2
chr5_156943457_156943608 0.25 ADAM19
 ADAM metallopeptidase domain 19
 13702
 0.17
chr10_81923875_81924026 0.25 ANXA11
 annexin A11
 2182
 0.32
chr8_98941895_98942046 0.25 MATN2
 matrilin 2
 1599
 0.45
chr12_71040955_71041106 0.25 PTPRB
 protein tyrosine phosphatase, receptor type, B
 9810
 0.28
chr16_88836823_88837632 0.25 PIEZO1
 piezo-type mechanosensitive ion channel component 1
 14392
 0.08
chr14_85937883_85938084 0.25 RP11-497E19.2
 Uncharacterized protein
 56960
 0.15
chr15_74880720_74881033 0.25 CLK3
 CDC-like kinase 3
 19837
 0.14
chr12_64400725_64400876 0.25 SRGAP1
 SLIT-ROBO Rho GTPase activating protein 1
 24495
 0.2
chr11_131783724_131783875 0.25 NTM
 neurotrimin
 2437
 0.34
chr14_55242379_55242669 0.25 SAMD4A
 sterile alpha motif domain containing 4A
 20973
 0.23
chr16_30724842_30725097 0.25 ENSG00000206755
 .
 3111
 0.11
chr17_40481304_40481455 0.25 STAT5A
 signal transducer and activator of transcription 5A
 23191
 0.11
chr10_33418933_33419614 0.25 ENSG00000263576
 .
 31709
 0.18
chr3_185450728_185450956 0.25 C3orf65
 chromosome 3 open reading frame 65
 19762
 0.2
chr1_208293570_208293721 0.25 PLXNA2
 plexin A2
 124020
 0.06
chr1_224716594_224716745 0.25 RP11-100E13.1
87253
 0.07
chr3_69813399_69813761 0.25 MITF
 microphthalmia-associated transcription factor
 618
 0.78
chr1_61427090_61427390 0.25 RP4-668G5.1
8719
 0.29
chr9_37943494_37943645 0.25 ENSG00000251745
 .
 6804
 0.24
chr5_72665716_72665867 0.25 FOXD1
 forkhead box D1
 78561
 0.09
chr5_169002894_169003181 0.25 SPDL1
 spindle apparatus coiled-coil protein 1
 7601
 0.23
chr2_188256029_188256180 0.25 CALCRL
 calcitonin receptor-like
 56875
 0.15
chr3_105078554_105078705 0.25 ALCAM
 activated leukocyte cell adhesion molecule
 7124
 0.35
chr7_82434629_82434780 0.24 PCLO
 piccolo presynaptic cytomatrix protein
 145360
 0.05
chr9_73518177_73518328 0.24 TRPM3
 transient receptor potential cation channel, subfamily M, member 3
 34278
 0.22
chr2_235213914_235214065 0.24 ARL4C
 ADP-ribosylation factor-like 4C
 191255
 0.03
chr2_217180660_217180876 0.24 AC069155.1
12720
 0.18
chr6_26103334_26103549 0.24 HIST1H4C
 histone cluster 1, H4c
 663
 0.44
chr7_116417479_116417780 0.24 MET
 met proto-oncogene
 400
 0.88
chr10_128613233_128613384 0.24 ENSG00000202487
 .
 3932
 0.29
chr4_13478395_13478680 0.24 RAB28
 RAB28, member RAS oncogene family
 2568
 0.38
chr6_52376418_52376603 0.24 TRAM2
 translocation associated membrane protein 2
 65203
 0.11
chr15_39481396_39481547 0.24 C15orf54
 chromosome 15 open reading frame 54
 61414
 0.14
chr4_152596771_152596922 0.24 RP11-164P12.3
1211
 0.5
chr17_39215738_39215889 0.24 KRTAP2-3
 keratin associated protein 2-3
 531
 0.48
chr12_52182216_52182367 0.24 AC068987.1
 HCG1997999; cDNA FLJ33996 fis, clone DFNES2008881
 21498
 0.2
chr5_180213979_180214228 0.24 CTC-205M6.5
766
 0.61
chr10_13981087_13981238 0.24 FRMD4A
 FERM domain containing 4A
 33207
 0.19
chr10_30236708_30236859 0.24 KIAA1462
 KIAA1462
 111670
 0.07
chr17_2082426_2082658 0.24 SMG6
 SMG6 nonsense mediated mRNA decay factor
 6070
 0.13
chr13_95740200_95740570 0.24 ENSG00000252335
 .
 68896
 0.12
chr16_70741421_70741612 0.24 VAC14
 Vac14 homolog (S. cerevisiae)
 7368
 0.15
chr4_77468211_77468426 0.24 ENSG00000207307
 .
 14838
 0.16
chr9_133640945_133641435 0.24 ABL1
 c-abl oncogene 1, non-receptor tyrosine kinase
 51823
 0.13
chr8_41548916_41549067 0.24 ANK1
 ankyrin 1, erythrocytic
 14706
 0.15
chr4_187767041_187767192 0.24 ENSG00000252382
 .
 11494
 0.3
chr12_77425923_77426193 0.24 E2F7
 E2F transcription factor 7
 18468
 0.27
chr14_61492762_61493358 0.24 SLC38A6
 solute carrier family 38, member 6
 16808
 0.21
chr1_16505237_16505388 0.24 ARHGEF19-AS1
 ARHGEF19 antisense RNA 1
 19037
 0.1
chr1_85950376_85950527 0.24 DDAH1
 dimethylarginine dimethylaminohydrolase 1
 19624
 0.21
chr6_14286162_14286313 0.24 ENSG00000238987
 .
 129544
 0.06
chr1_94429653_94429804 0.24 ABCA4
 ATP-binding cassette, sub-family A (ABC1), member 4
 47453
 0.13
chrX_20085662_20085960 0.24 MAP7D2
 MAP7 domain containing 2
 10916
 0.18
chr7_81476151_81476440 0.24 ENSG00000263416
 .
 73291
 0.11
chr3_52205760_52205911 0.23 POC1A
 POC1 centriolar protein A
 17129
 0.12
chr5_98396799_98396950 0.23 ENSG00000200351
 .
 124423
 0.06
chr1_200341478_200341663 0.23 ZNF281
 zinc finger protein 281
 37550
 0.22
chr5_114738428_114738579 0.23 CCDC112
 coiled-coil domain containing 112
 105975
 0.06
chr21_18864726_18865102 0.23 ENSG00000266195
 .
 13857
 0.15
chr6_11195366_11195517 0.23 RP3-510L9.1
21756
 0.19
chr4_122613058_122613356 0.23 ANXA5
 annexin A5
 4910
 0.26
chr8_123671514_123671802 0.23 ENSG00000238901
 .
 11872
 0.28
chr5_121518729_121518882 0.23 CTC-441N14.1
27095
 0.17
chr1_146638682_146638833 0.23 PRKAB2
 protein kinase, AMP-activated, beta 2 non-catalytic subunit
 5289
 0.17
chr19_49554011_49554162 0.23 CGB8
 chorionic gonadotropin, beta polypeptide 8
 1686
 0.12
chr18_46069398_46069549 0.23 CTIF
 CBP80/20-dependent translation initiation factor
 3007
 0.33
chr13_110492993_110493226 0.23 IRS2
 insulin receptor substrate 2
 54194
 0.15
chr8_18992583_18992734 0.23 PSD3
 pleckstrin and Sec7 domain containing 3
 50418
 0.18
chr1_33809231_33809577 0.23 PHC2
 polyhomeotic homolog 2 (Drosophila)
 6082
 0.12
chr9_127162086_127162596 0.23 PSMB7
 proteasome (prosome, macropain) subunit, beta type, 7
 15377
 0.19
chr1_12524294_12524445 0.23 VPS13D
 vacuolar protein sorting 13 homolog D (S. cerevisiae)
 626
 0.77
chr1_84719853_84720004 0.23 ENSG00000199959
 .
 23076
 0.21
chr8_49292717_49292868 0.23 ENSG00000252710
 .
 72202
 0.13
chr3_185463874_185464186 0.23 ENSG00000265470
 .
 21662
 0.19
chr16_68333106_68333257 0.23 SLC7A6OS
 solute carrier family 7, member 6 opposite strand
 4951
 0.09
chr1_54801806_54802163 0.23 RP5-997D24.3
50906
 0.12
chr17_48138498_48138649 0.23 ITGA3
 integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)
 4769
 0.15
chr1_178509729_178509880 0.23 C1orf220
 chromosome 1 open reading frame 220
 2083
 0.23
chr13_27193375_27193609 0.23 WASF3-AS1
 WASF3 antisense RNA 1
 22009
 0.24
chr15_64721787_64722615 0.23 TRIP4
 thyroid hormone receptor interactor 4
 5887
 0.12
chr5_149886580_149886731 0.23 NDST1
 N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1
 1019
 0.53
chr3_50138493_50138644 0.23 RBM5
 RNA binding motif protein 5
 10765
 0.14
chr12_13357086_13357299 0.23 EMP1
 epithelial membrane protein 1
 7253
 0.27
chrX_6962695_6962846 0.23 ENSG00000264268
 .
 103131
 0.08

Histogram of CRE-TSS distances for CREs targeted by :

Histogram of

Rank distribution of CRE target scores:

Histogram of target CRE score.

Distribution of target CREs across different genomic regions:

Weighted Piechart of Weighted Piechart of Weighted Piechart of

Network of associatons between targets according to the STRING database.

First level regulatory network of OTX2_CRX

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.5 GO:0071694 sequestering of extracellular ligand from receptor(GO:0035581) sequestering of TGFbeta in extracellular matrix(GO:0035583) protein localization to extracellular region(GO:0071692) maintenance of protein location in extracellular region(GO:0071694) extracellular regulation of signal transduction(GO:1900115) extracellular negative regulation of signal transduction(GO:1900116)
0.1 0.6 GO:0060666 dichotomous subdivision of terminal units involved in salivary gland branching(GO:0060666)
0.1 0.2 GO:0060831 smoothened signaling pathway involved in dorsal/ventral neural tube patterning(GO:0060831)
0.1 0.4 GO:0031340 positive regulation of vesicle fusion(GO:0031340)
0.1 0.3 GO:0001996 positive regulation of heart rate by epinephrine-norepinephrine(GO:0001996)
0.1 0.3 GO:0032509 endosome transport via multivesicular body sorting pathway(GO:0032509)
0.1 0.4 GO:0048625 myoblast fate commitment(GO:0048625)
0.1 0.2 GO:0033173 calcineurin-NFAT signaling cascade(GO:0033173)
0.1 0.3 GO:0048702 embryonic neurocranium morphogenesis(GO:0048702)
0.1 0.2 GO:0060083 smooth muscle contraction involved in micturition(GO:0060083)
0.1 0.2 GO:0022605 oogenesis stage(GO:0022605)
0.1 0.1 GO:0060665 regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling(GO:0060665)
0.1 0.4 GO:0097061 dendritic spine morphogenesis(GO:0060997) regulation of dendritic spine morphogenesis(GO:0061001) dendritic spine organization(GO:0097061)
0.1 0.2 GO:0035426 extracellular matrix-cell signaling(GO:0035426)
0.1 0.2 GO:0072201 negative regulation of mesenchymal cell proliferation(GO:0072201)
0.1 0.2 GO:0010837 regulation of keratinocyte proliferation(GO:0010837)
0.1 0.2 GO:0010842 retina layer formation(GO:0010842)
0.1 0.4 GO:0007171 activation of transmembrane receptor protein tyrosine kinase activity(GO:0007171)
0.1 0.3 GO:0021535 cell migration in hindbrain(GO:0021535)
0.1 0.1 GO:0060648 mammary gland bud morphogenesis(GO:0060648)
0.1 0.2 GO:0015705 iodide transport(GO:0015705)
0.1 0.1 GO:0021825 cerebral cortex tangential migration using cell-cell interactions(GO:0021823) substrate-dependent cerebral cortex tangential migration(GO:0021825) postnatal olfactory bulb interneuron migration(GO:0021827)
0.1 0.2 GO:0007028 cytoplasm organization(GO:0007028)
0.1 0.2 GO:0019348 polyprenol metabolic process(GO:0016093) dolichol metabolic process(GO:0019348)
0.1 0.2 GO:0051124 synaptic growth at neuromuscular junction(GO:0051124)
0.1 0.2 GO:0010766 negative regulation of sodium ion transport(GO:0010766)
0.0 0.3 GO:0007185 transmembrane receptor protein tyrosine phosphatase signaling pathway(GO:0007185)
0.0 0.2 GO:0048755 branching morphogenesis of a nerve(GO:0048755)
0.0 0.2 GO:0048149 behavioral response to ethanol(GO:0048149)
0.0 0.1 GO:0006065 UDP-glucuronate biosynthetic process(GO:0006065)
0.0 0.2 GO:0060013 righting reflex(GO:0060013)
0.0 0.1 GO:2000114 regulation of establishment of cell polarity(GO:2000114)
0.0 0.2 GO:0051497 negative regulation of stress fiber assembly(GO:0051497)
0.0 0.1 GO:0045657 positive regulation of monocyte differentiation(GO:0045657)
0.0 0.1 GO:0033688 regulation of osteoblast proliferation(GO:0033688)
0.0 0.1 GO:0033603 positive regulation of dopamine secretion(GO:0033603)
0.0 0.1 GO:0035511 oxidative DNA demethylation(GO:0035511)
0.0 0.2 GO:0009128 purine nucleoside monophosphate catabolic process(GO:0009128) ribonucleoside monophosphate catabolic process(GO:0009158) purine ribonucleoside monophosphate catabolic process(GO:0009169)
0.0 0.1 GO:0055098 response to low-density lipoprotein particle(GO:0055098)
0.0 0.2 GO:0048343 paraxial mesodermal cell differentiation(GO:0048342) paraxial mesodermal cell fate commitment(GO:0048343)
0.0 0.2 GO:0090162 establishment of epithelial cell polarity(GO:0090162)
0.0 0.2 GO:0016266 O-glycan processing(GO:0016266)
0.0 0.2 GO:0071318 cellular response to ATP(GO:0071318)
0.0 0.1 GO:0003308 negative regulation of Wnt signaling pathway involved in heart development(GO:0003308)
0.0 0.1 GO:0071277 cellular response to calcium ion(GO:0071277)
0.0 0.1 GO:0070141 response to UV-A(GO:0070141)
0.0 0.1 GO:0010757 negative regulation of plasminogen activation(GO:0010757)
0.0 0.1 GO:0051014 actin filament severing(GO:0051014)
0.0 0.0 GO:0014067 negative regulation of phosphatidylinositol 3-kinase signaling(GO:0014067)
0.0 0.0 GO:2000542 negative regulation of gastrulation(GO:2000542)
0.0 0.1 GO:0060528 secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development(GO:0060528)
0.0 0.1 GO:0071800 podosome assembly(GO:0071800)
0.0 0.1 GO:0010761 fibroblast migration(GO:0010761)
0.0 0.1 GO:0007221 positive regulation of transcription of Notch receptor target(GO:0007221)
0.0 0.1 GO:0001543 ovarian follicle rupture(GO:0001543)
0.0 0.1 GO:0043490 malate-aspartate shuttle(GO:0043490)
0.0 0.1 GO:0010966 regulation of phosphate transport(GO:0010966)
0.0 0.0 GO:0035385 Roundabout signaling pathway(GO:0035385)
0.0 0.0 GO:0021798 forebrain dorsal/ventral pattern formation(GO:0021798)
0.0 0.0 GO:0060129 thyroid-stimulating hormone-secreting cell differentiation(GO:0060129)
0.0 0.2 GO:0048268 clathrin coat assembly(GO:0048268)
0.0 0.4 GO:0007026 negative regulation of microtubule depolymerization(GO:0007026)
0.0 0.1 GO:0046607 positive regulation of centrosome cycle(GO:0046607)
0.0 0.1 GO:0045074 interleukin-10 biosynthetic process(GO:0042091) regulation of interleukin-10 biosynthetic process(GO:0045074)
0.0 0.1 GO:2000050 regulation of non-canonical Wnt signaling pathway(GO:2000050) regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000095)
0.0 0.1 GO:0001973 adenosine receptor signaling pathway(GO:0001973) G-protein coupled purinergic receptor signaling pathway(GO:0035588)
0.0 0.1 GO:0032455 nerve growth factor processing(GO:0032455)
0.0 0.1 GO:0006663 platelet activating factor biosynthetic process(GO:0006663)
0.0 0.2 GO:0051382 kinetochore assembly(GO:0051382)
0.0 0.1 GO:0032347 regulation of ketone biosynthetic process(GO:0010566) regulation of aldosterone metabolic process(GO:0032344) regulation of aldosterone biosynthetic process(GO:0032347)
0.0 0.1 GO:0002903 negative regulation of B cell apoptotic process(GO:0002903)
0.0 0.1 GO:0006007 glucose catabolic process(GO:0006007)
0.0 0.1 GO:0032413 negative regulation of ion transmembrane transporter activity(GO:0032413)
0.0 0.1 GO:0051305 chromosome movement towards spindle pole(GO:0051305)
0.0 0.0 GO:0046121 deoxyribonucleoside catabolic process(GO:0046121)
0.0 0.1 GO:0016241 regulation of macroautophagy(GO:0016241)
0.0 0.2 GO:1904893 negative regulation of JAK-STAT cascade(GO:0046426) negative regulation of STAT cascade(GO:1904893)
0.0 0.0 GO:0001553 luteinization(GO:0001553)
0.0 0.1 GO:0045662 negative regulation of myoblast differentiation(GO:0045662)
0.0 0.1 GO:2000647 negative regulation of neuroblast proliferation(GO:0007406) negative regulation of neural precursor cell proliferation(GO:2000178) negative regulation of stem cell proliferation(GO:2000647)
0.0 0.1 GO:0043129 surfactant homeostasis(GO:0043129) chemical homeostasis within a tissue(GO:0048875)
0.0 0.1 GO:0019471 peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401) 4-hydroxyproline metabolic process(GO:0019471) peptidyl-proline hydroxylation(GO:0019511)
0.0 0.1 GO:0043589 skin morphogenesis(GO:0043589)
0.0 0.1 GO:0045747 positive regulation of Notch signaling pathway(GO:0045747)
0.0 0.1 GO:0010661 positive regulation of muscle cell apoptotic process(GO:0010661) positive regulation of smooth muscle cell apoptotic process(GO:0034393)
0.0 0.1 GO:0060058 apoptotic process involved in mammary gland involution(GO:0060057) positive regulation of apoptotic process involved in mammary gland involution(GO:0060058) positive regulation of apoptotic process involved in morphogenesis(GO:1902339) regulation of mammary gland involution(GO:1903519) positive regulation of mammary gland involution(GO:1903521) positive regulation of apoptotic process involved in development(GO:1904747)
0.0 0.1 GO:0002043 blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:0002043)
0.0 0.1 GO:0060394 negative regulation of pathway-restricted SMAD protein phosphorylation(GO:0060394)
0.0 0.1 GO:0045715 negative regulation of low-density lipoprotein particle receptor biosynthetic process(GO:0045715)
0.0 0.1 GO:0006048 UDP-N-acetylglucosamine biosynthetic process(GO:0006048)
0.0 0.1 GO:0002678 positive regulation of chronic inflammatory response(GO:0002678)
0.0 0.1 GO:0060039 pericardium development(GO:0060039)
0.0 0.1 GO:0072386 plus-end-directed vesicle transport along microtubule(GO:0072383) plus-end-directed organelle transport along microtubule(GO:0072386)
0.0 0.1 GO:0019805 quinolinate biosynthetic process(GO:0019805)
0.0 0.0 GO:0042637 catagen(GO:0042637)
0.0 0.1 GO:0070874 negative regulation of glycogen metabolic process(GO:0070874)
0.0 0.1 GO:0006910 phagocytosis, recognition(GO:0006910)
0.0 0.2 GO:0050957 equilibrioception(GO:0050957)
0.0 0.2 GO:0000052 citrulline metabolic process(GO:0000052)
0.0 0.0 GO:0061318 renal filtration cell differentiation(GO:0061318) glomerular epithelium development(GO:0072010) glomerular visceral epithelial cell differentiation(GO:0072112) glomerular epithelial cell differentiation(GO:0072311)
0.0 0.1 GO:0033023 mast cell homeostasis(GO:0033023) mast cell apoptotic process(GO:0033024) regulation of mast cell apoptotic process(GO:0033025)
0.0 0.1 GO:0042487 regulation of odontogenesis of dentin-containing tooth(GO:0042487)
0.0 0.0 GO:0045578 negative regulation of B cell differentiation(GO:0045578)
0.0 0.1 GO:0042732 D-xylose metabolic process(GO:0042732)
0.0 0.0 GO:0002689 negative regulation of leukocyte chemotaxis(GO:0002689)
0.0 0.1 GO:0006930 substrate-dependent cell migration, cell extension(GO:0006930)
0.0 0.2 GO:0002040 sprouting angiogenesis(GO:0002040)
0.0 0.4 GO:0030199 collagen fibril organization(GO:0030199)
0.0 0.1 GO:0022617 extracellular matrix disassembly(GO:0022617)
0.0 0.0 GO:0061072 iris morphogenesis(GO:0061072)
0.0 0.0 GO:0060872 semicircular canal development(GO:0060872)
0.0 0.0 GO:0046826 negative regulation of protein export from nucleus(GO:0046826)
0.0 0.3 GO:0048286 lung alveolus development(GO:0048286)
0.0 0.0 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.0 0.1 GO:0045091 regulation of single stranded viral RNA replication via double stranded DNA intermediate(GO:0045091)
0.0 0.1 GO:0030579 ubiquitin-dependent SMAD protein catabolic process(GO:0030579)
0.0 0.1 GO:0045905 translational frameshifting(GO:0006452) positive regulation of translational elongation(GO:0045901) positive regulation of translational termination(GO:0045905)
0.0 0.1 GO:0007598 blood coagulation, extrinsic pathway(GO:0007598)
0.0 0.1 GO:0031269 pseudopodium assembly(GO:0031269) regulation of pseudopodium assembly(GO:0031272) positive regulation of pseudopodium assembly(GO:0031274)
0.0 0.1 GO:0060014 granulosa cell differentiation(GO:0060014)
0.0 0.1 GO:0033197 response to vitamin E(GO:0033197)
0.0 0.1 GO:0031536 positive regulation of exit from mitosis(GO:0031536)
0.0 0.1 GO:0006667 sphinganine metabolic process(GO:0006667)
0.0 0.2 GO:1903846 positive regulation of transforming growth factor beta receptor signaling pathway(GO:0030511) positive regulation of cellular response to transforming growth factor beta stimulus(GO:1903846)
0.0 0.1 GO:0009648 photoperiodism(GO:0009648)
0.0 0.1 GO:0001547 antral ovarian follicle growth(GO:0001547)
0.0 0.0 GO:0007021 tubulin complex assembly(GO:0007021)
0.0 0.2 GO:0009629 response to gravity(GO:0009629)
0.0 0.0 GO:0014912 negative regulation of smooth muscle cell migration(GO:0014912)
0.0 0.1 GO:0017000 antibiotic metabolic process(GO:0016999) antibiotic biosynthetic process(GO:0017000)
0.0 0.0 GO:0070254 mucus secretion(GO:0070254)
0.0 0.1 GO:0042819 pyridoxine metabolic process(GO:0008614) pyridoxine biosynthetic process(GO:0008615) vitamin B6 metabolic process(GO:0042816) vitamin B6 biosynthetic process(GO:0042819)
0.0 0.1 GO:0070102 interleukin-6-mediated signaling pathway(GO:0070102)
0.0 0.1 GO:0060390 regulation of SMAD protein import into nucleus(GO:0060390)
0.0 0.0 GO:0051547 regulation of keratinocyte migration(GO:0051547) positive regulation of keratinocyte migration(GO:0051549)
0.0 0.1 GO:0060710 chorio-allantoic fusion(GO:0060710)
0.0 0.1 GO:0006590 thyroid hormone generation(GO:0006590)
0.0 0.0 GO:0014848 urinary tract smooth muscle contraction(GO:0014848)
0.0 0.1 GO:0050774 negative regulation of dendrite morphogenesis(GO:0050774)
0.0 0.2 GO:0007567 parturition(GO:0007567)
0.0 0.1 GO:0032236 obsolete positive regulation of calcium ion transport via store-operated calcium channel activity(GO:0032236)
0.0 0.1 GO:0033327 Leydig cell differentiation(GO:0033327)
0.0 0.2 GO:0032964 collagen biosynthetic process(GO:0032964)
0.0 0.1 GO:0009296 obsolete flagellum assembly(GO:0009296)
0.0 0.0 GO:0070427 nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070427)
0.0 0.1 GO:0030321 transepithelial chloride transport(GO:0030321)
0.0 0.0 GO:0090073 positive regulation of protein homodimerization activity(GO:0090073)
0.0 0.1 GO:0032525 somite rostral/caudal axis specification(GO:0032525)
0.0 0.1 GO:0006106 fumarate metabolic process(GO:0006106)
0.0 0.0 GO:0045906 negative regulation of vasoconstriction(GO:0045906)
0.0 0.1 GO:0090084 negative regulation of inclusion body assembly(GO:0090084)
0.0 0.1 GO:0046549 retinal cone cell differentiation(GO:0042670) retinal cone cell development(GO:0046549)
0.0 0.1 GO:0051898 negative regulation of protein kinase B signaling(GO:0051898)
0.0 0.0 GO:0034135 regulation of toll-like receptor 2 signaling pathway(GO:0034135)
0.0 0.1 GO:0060040 retinal bipolar neuron differentiation(GO:0060040)
0.0 0.2 GO:0002026 regulation of the force of heart contraction(GO:0002026)
0.0 0.0 GO:0010719 negative regulation of epithelial to mesenchymal transition(GO:0010719)
0.0 0.1 GO:0042693 muscle cell fate commitment(GO:0042693)
0.0 0.1 GO:0008049 male courtship behavior(GO:0008049)
0.0 0.1 GO:0090273 regulation of somatostatin secretion(GO:0090273)
0.0 0.0 GO:0048853 forebrain morphogenesis(GO:0048853)
0.0 0.1 GO:0070295 renal water absorption(GO:0070295)
0.0 0.1 GO:0043569 negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569)
0.0 0.0 GO:0060999 positive regulation of dendritic spine development(GO:0060999)
0.0 0.1 GO:0045627 positive regulation of T-helper 1 cell differentiation(GO:0045627)
0.0 0.1 GO:0034720 histone H3-K4 demethylation(GO:0034720)
0.0 0.0 GO:0048003 antigen processing and presentation of lipid antigen via MHC class Ib(GO:0048003)
0.0 0.1 GO:0016246 RNA interference(GO:0016246)
0.0 0.1 GO:0031641 regulation of myelination(GO:0031641)
0.0 0.2 GO:0008045 motor neuron axon guidance(GO:0008045)
0.0 0.1 GO:0031000 response to caffeine(GO:0031000)
0.0 0.0 GO:0044240 multicellular organism lipid catabolic process(GO:0044240)
0.0 0.0 GO:0046882 negative regulation of follicle-stimulating hormone secretion(GO:0046882)
0.0 0.0 GO:0033148 positive regulation of intracellular estrogen receptor signaling pathway(GO:0033148)
0.0 0.0 GO:0048643 positive regulation of skeletal muscle tissue development(GO:0048643)
0.0 0.0 GO:0046021 regulation of transcription from RNA polymerase II promoter, mitotic(GO:0046021) positive regulation of transcription from RNA polymerase II promoter during mitosis(GO:0046022)
0.0 0.1 GO:0010765 positive regulation of sodium ion transport(GO:0010765)
0.0 0.1 GO:0000301 retrograde transport, vesicle recycling within Golgi(GO:0000301)
0.0 0.0 GO:0010980 regulation of vitamin D 24-hydroxylase activity(GO:0010979) positive regulation of vitamin D 24-hydroxylase activity(GO:0010980)
0.0 0.1 GO:0045600 positive regulation of fat cell differentiation(GO:0045600)
0.0 0.0 GO:0003170 heart valve development(GO:0003170) heart valve morphogenesis(GO:0003179)
0.0 0.1 GO:0007494 midgut development(GO:0007494)
0.0 0.1 GO:0071028 RNA surveillance(GO:0071025) nuclear RNA surveillance(GO:0071027) nuclear mRNA surveillance(GO:0071028)
0.0 0.0 GO:0046886 positive regulation of hormone metabolic process(GO:0032352) positive regulation of hormone biosynthetic process(GO:0046886)
0.0 0.0 GO:0051451 myoblast migration(GO:0051451)
0.0 0.1 GO:0006448 regulation of translational elongation(GO:0006448)
0.0 0.1 GO:0044314 protein K27-linked ubiquitination(GO:0044314)
0.0 0.1 GO:0007603 phototransduction, visible light(GO:0007603)
0.0 0.0 GO:0003097 renal water transport(GO:0003097)
0.0 0.0 GO:0051481 negative regulation of cytosolic calcium ion concentration(GO:0051481)
0.0 0.3 GO:0030574 collagen catabolic process(GO:0030574)
0.0 0.1 GO:0032288 myelin assembly(GO:0032288)
0.0 0.0 GO:0001778 plasma membrane repair(GO:0001778)
0.0 0.0 GO:0010507 negative regulation of autophagy(GO:0010507)
0.0 0.0 GO:0016199 axon midline choice point recognition(GO:0016199)
0.0 0.2 GO:0006942 regulation of striated muscle contraction(GO:0006942)
0.0 0.1 GO:0043985 histone H4-R3 methylation(GO:0043985)
0.0 0.0 GO:0006591 ornithine metabolic process(GO:0006591)
0.0 0.0 GO:0060638 mesenchymal-epithelial cell signaling(GO:0060638)
0.0 0.0 GO:0042501 serine phosphorylation of STAT protein(GO:0042501)
0.0 0.0 GO:0048867 stem cell fate commitment(GO:0048865) stem cell fate determination(GO:0048867)
0.0 0.0 GO:0032823 regulation of natural killer cell differentiation(GO:0032823) positive regulation of natural killer cell differentiation(GO:0032825)
0.0 0.1 GO:0045880 positive regulation of smoothened signaling pathway(GO:0045880)
0.0 0.1 GO:0006534 cysteine metabolic process(GO:0006534)
0.0 0.2 GO:0048384 retinoic acid receptor signaling pathway(GO:0048384)
0.0 0.1 GO:0007095 mitotic G2 DNA damage checkpoint(GO:0007095)
0.0 0.1 GO:0060259 regulation of feeding behavior(GO:0060259)
0.0 0.3 GO:0010811 positive regulation of cell-substrate adhesion(GO:0010811)
0.0 0.0 GO:0030952 establishment or maintenance of cytoskeleton polarity(GO:0030952)
0.0 0.0 GO:0016080 synaptic vesicle targeting(GO:0016080)
0.0 0.0 GO:0016139 glycoside metabolic process(GO:0016137) glycoside catabolic process(GO:0016139)
0.0 0.0 GO:0051151 negative regulation of smooth muscle cell differentiation(GO:0051151)
0.0 0.1 GO:0006895 Golgi to endosome transport(GO:0006895) Golgi to vacuole transport(GO:0006896)
0.0 0.1 GO:0042253 granulocyte macrophage colony-stimulating factor biosynthetic process(GO:0042253)
0.0 0.1 GO:0045885 obsolete positive regulation of survival gene product expression(GO:0045885)
0.0 0.1 GO:0051482 positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway(GO:0051482)
0.0 0.0 GO:0001574 ganglioside biosynthetic process(GO:0001574)
0.0 0.0 GO:0045792 negative regulation of cell size(GO:0045792)
0.0 0.1 GO:0033235 positive regulation of protein sumoylation(GO:0033235)
0.0 0.1 GO:0006069 ethanol metabolic process(GO:0006067) ethanol oxidation(GO:0006069)
0.0 0.1 GO:0032780 negative regulation of ATPase activity(GO:0032780)
0.0 0.1 GO:0009404 toxin metabolic process(GO:0009404)
0.0 0.0 GO:0043276 anoikis(GO:0043276)
0.0 0.1 GO:0007274 neuromuscular synaptic transmission(GO:0007274)
0.0 0.1 GO:0051818 disruption of cells of other organism involved in symbiotic interaction(GO:0051818) killing of cells in other organism involved in symbiotic interaction(GO:0051883)
0.0 0.1 GO:0090136 epithelial cell-cell adhesion(GO:0090136)
0.0 0.0 GO:0010193 response to ozone(GO:0010193)
0.0 0.0 GO:0030091 protein repair(GO:0030091)
0.0 0.1 GO:0050922 negative regulation of chemotaxis(GO:0050922)
0.0 0.0 GO:0034638 phosphatidylcholine catabolic process(GO:0034638)
0.0 0.0 GO:0051771 negative regulation of nitric-oxide synthase biosynthetic process(GO:0051771)
0.0 0.0 GO:0048861 leukemia inhibitory factor signaling pathway(GO:0048861)
0.0 0.0 GO:0000101 sulfur amino acid transport(GO:0000101) L-cystine transport(GO:0015811)
0.0 0.0 GO:0060023 soft palate development(GO:0060023)
0.0 0.1 GO:0006776 vitamin A metabolic process(GO:0006776)
0.0 0.0 GO:0046083 adenine salvage(GO:0006168) purine nucleobase salvage(GO:0043096) adenine metabolic process(GO:0046083) adenine biosynthetic process(GO:0046084)
0.0 0.0 GO:0072385 minus-end-directed organelle transport along microtubule(GO:0072385)
0.0 0.1 GO:0051096 positive regulation of helicase activity(GO:0051096)
0.0 0.2 GO:0045104 intermediate filament cytoskeleton organization(GO:0045104)
0.0 0.0 GO:0002076 osteoblast development(GO:0002076)
0.0 0.0 GO:0031117 positive regulation of microtubule depolymerization(GO:0031117)
0.0 0.1 GO:0014050 negative regulation of glutamate secretion(GO:0014050)
0.0 0.1 GO:0070189 kynurenine metabolic process(GO:0070189)
0.0 0.1 GO:0051927 obsolete negative regulation of calcium ion transport via voltage-gated calcium channel activity(GO:0051927)
0.0 0.0 GO:0006564 L-serine biosynthetic process(GO:0006564)
0.0 0.0 GO:0090116 DNA methylation on cytosine(GO:0032776) C-5 methylation of cytosine(GO:0090116)
0.0 0.1 GO:0015871 choline transport(GO:0015871)
0.0 0.0 GO:0032650 regulation of interleukin-1 alpha production(GO:0032650) positive regulation of interleukin-1 alpha production(GO:0032730)
0.0 0.0 GO:2000300 regulation of synaptic vesicle transport(GO:1902803) regulation of synaptic vesicle exocytosis(GO:2000300)
0.0 0.0 GO:0043983 histone H4-K12 acetylation(GO:0043983)
0.0 0.0 GO:0030432 peristalsis(GO:0030432)
0.0 0.0 GO:0006654 phosphatidic acid biosynthetic process(GO:0006654)
0.0 0.0 GO:0021591 ventricular system development(GO:0021591)
0.0 0.0 GO:0002025 vasodilation by norepinephrine-epinephrine involved in regulation of systemic arterial blood pressure(GO:0002025)
0.0 0.2 GO:0048010 vascular endothelial growth factor receptor signaling pathway(GO:0048010)
0.0 0.1 GO:0090559 regulation of mitochondrial membrane permeability(GO:0046902) regulation of membrane permeability(GO:0090559)
0.0 0.0 GO:0042268 regulation of cytolysis(GO:0042268)
0.0 0.1 GO:0006646 phosphatidylethanolamine biosynthetic process(GO:0006646) phosphatidylethanolamine metabolic process(GO:0046337)
0.0 0.0 GO:0048148 behavioral response to cocaine(GO:0048148)
0.0 0.0 GO:0000710 meiotic mismatch repair(GO:0000710)
0.0 0.3 GO:0046134 pyrimidine nucleoside biosynthetic process(GO:0046134)
0.0 0.0 GO:0060068 female genitalia morphogenesis(GO:0048807) vagina development(GO:0060068)
0.0 0.0 GO:0043497 regulation of protein heterodimerization activity(GO:0043497)
0.0 0.1 GO:0009396 folic acid-containing compound biosynthetic process(GO:0009396)
0.0 0.0 GO:0030538 embryonic genitalia morphogenesis(GO:0030538)
0.0 0.0 GO:0046838 phosphorylated carbohydrate dephosphorylation(GO:0046838) inositol phosphate dephosphorylation(GO:0046855)
0.0 0.0 GO:0015793 glycerol transport(GO:0015793)
0.0 0.2 GO:0007566 embryo implantation(GO:0007566)
0.0 0.1 GO:0018027 peptidyl-lysine dimethylation(GO:0018027)
0.0 0.1 GO:0019369 arachidonic acid metabolic process(GO:0019369)
0.0 0.0 GO:0019695 choline metabolic process(GO:0019695)
0.0 0.0 GO:0003010 voluntary skeletal muscle contraction(GO:0003010) twitch skeletal muscle contraction(GO:0014721)
0.0 0.0 GO:0030388 fructose 1,6-bisphosphate metabolic process(GO:0030388)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0030934 anchoring collagen complex(GO:0030934)
0.1 0.2 GO:0032059 bleb(GO:0032059)
0.1 0.1 GO:0030132 clathrin coat of coated pit(GO:0030132)
0.0 0.2 GO:0030056 hemidesmosome(GO:0030056)
0.0 0.3 GO:0002102 podosome(GO:0002102)
0.0 0.3 GO:0098645 network-forming collagen trimer(GO:0098642) collagen network(GO:0098645)
0.0 0.1 GO:0005899 insulin receptor complex(GO:0005899)
0.0 0.0 GO:0005862 muscle thin filament tropomyosin(GO:0005862)
0.0 0.3 GO:0030128 AP-2 adaptor complex(GO:0030122) clathrin coat of endocytic vesicle(GO:0030128)
0.0 0.1 GO:0005945 6-phosphofructokinase complex(GO:0005945)
0.0 0.2 GO:0016342 catenin complex(GO:0016342)
0.0 0.1 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.0 0.1 GO:0043260 laminin-11 complex(GO:0043260)
0.0 0.1 GO:0033018 sarcoplasmic reticulum lumen(GO:0033018)
0.0 0.1 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.0 0.1 GO:0042405 nuclear inclusion body(GO:0042405)
0.0 0.2 GO:0005861 troponin complex(GO:0005861)
0.0 0.1 GO:0005588 collagen type V trimer(GO:0005588)
0.0 0.2 GO:0005614 interstitial matrix(GO:0005614)
0.0 0.6 GO:0001725 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.0 0.4 GO:0009925 basal plasma membrane(GO:0009925)
0.0 0.2 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.0 0.1 GO:0001527 microfibril(GO:0001527)
0.0 0.4 GO:0030057 desmosome(GO:0030057)
0.0 0.1 GO:0043625 delta DNA polymerase complex(GO:0043625)
0.0 0.2 GO:0000780 condensed nuclear chromosome, centromeric region(GO:0000780)
0.0 0.0 GO:0043083 synaptic cleft(GO:0043083)
0.0 0.1 GO:0005828 kinetochore microtubule(GO:0005828)
0.0 0.1 GO:0046540 U4/U6 x U5 tri-snRNP complex(GO:0046540) spliceosomal tri-snRNP complex(GO:0097526)
0.0 0.1 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.0 0.2 GO:0031233 intrinsic component of external side of plasma membrane(GO:0031233)
0.0 1.0 GO:0030496 midbody(GO:0030496)
0.0 0.1 GO:0051233 spindle midzone(GO:0051233)
0.0 0.1 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.0 0.1 GO:0005896 interleukin-6 receptor complex(GO:0005896)
0.0 0.1 GO:0005581 collagen trimer(GO:0005581)
0.0 0.0 GO:0071062 alphav-beta3 integrin-vitronectin complex(GO:0071062)
0.0 0.1 GO:0071546 pi-body(GO:0071546)
0.0 0.0 GO:0032449 CBM complex(GO:0032449)
0.0 0.1 GO:0031143 pseudopodium(GO:0031143)
0.0 0.0 GO:0070044 synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044)
0.0 0.0 GO:0000176 nuclear exosome (RNase complex)(GO:0000176)
0.0 0.0 GO:0071664 catenin-TCF7L2 complex(GO:0071664)
0.0 0.1 GO:0030688 preribosome, small subunit precursor(GO:0030688)
0.0 0.4 GO:0008305 integrin complex(GO:0008305) protein complex involved in cell adhesion(GO:0098636)
0.0 0.0 GO:0070852 cell body fiber(GO:0070852)
0.0 0.1 GO:0014704 intercalated disc(GO:0014704) cell-cell contact zone(GO:0044291)
0.0 0.0 GO:0005686 U2 snRNP(GO:0005686)
0.0 0.2 GO:0005913 cell-cell adherens junction(GO:0005913)
0.0 0.1 GO:0033180 proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.0 0.4 GO:0030018 Z disc(GO:0030018)
0.0 0.5 GO:0016459 myosin complex(GO:0016459)
0.0 0.3 GO:0030140 trans-Golgi network transport vesicle(GO:0030140)
0.0 0.1 GO:0098643 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.0 0.1 GO:0043202 lysosomal lumen(GO:0043202)
0.0 0.0 GO:0043230 extracellular organelle(GO:0043230) extracellular exosome(GO:0070062) extracellular vesicle(GO:1903561)
0.0 3.1 GO:0005578 proteinaceous extracellular matrix(GO:0005578)
0.0 0.1 GO:0001917 photoreceptor inner segment(GO:0001917)
0.0 0.1 GO:0031941 filamentous actin(GO:0031941)
0.0 0.0 GO:0035145 exon-exon junction complex(GO:0035145)
0.0 0.0 GO:0005638 lamin filament(GO:0005638)
0.0 0.3 GO:0030665 clathrin-coated vesicle membrane(GO:0030665)
0.0 0.1 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.0 0.2 GO:0019861 obsolete flagellum(GO:0019861)
0.0 0.6 GO:0030016 myofibril(GO:0030016)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.6 GO:0017154 semaphorin receptor activity(GO:0017154)
0.1 0.3 GO:0019834 phospholipase A2 inhibitor activity(GO:0019834)
0.1 0.3 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.1 0.2 GO:0030215 semaphorin receptor binding(GO:0030215)
0.1 0.3 GO:0001099 basal transcription machinery binding(GO:0001098) basal RNA polymerase II transcription machinery binding(GO:0001099)
0.1 0.3 GO:0015016 [heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
0.1 0.3 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
0.1 0.2 GO:0003680 AT DNA binding(GO:0003680)
0.1 0.4 GO:0003708 retinoic acid receptor activity(GO:0003708)
0.1 0.2 GO:0004800 thyroxine 5'-deiodinase activity(GO:0004800)
0.0 0.3 GO:0017166 vinculin binding(GO:0017166)
0.0 0.1 GO:0042799 histone methyltransferase activity (H4-K20 specific)(GO:0042799)
0.0 0.2 GO:0016934 extracellular-glycine-gated ion channel activity(GO:0016933) extracellular-glycine-gated chloride channel activity(GO:0016934)
0.0 0.1 GO:0004117 calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117)
0.0 0.1 GO:0050501 hyaluronan synthase activity(GO:0050501)
0.0 0.1 GO:0043515 kinetochore binding(GO:0043515)
0.0 0.1 GO:0050508 glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0050508)
0.0 0.2 GO:0042805 actinin binding(GO:0042805)
0.0 0.1 GO:0004013 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.0 0.1 GO:0016623 oxidoreductase activity, acting on the aldehyde or oxo group of donors, oxygen as acceptor(GO:0016623)
0.0 0.1 GO:0002162 dystroglycan binding(GO:0002162)
0.0 0.1 GO:0005006 epidermal growth factor-activated receptor activity(GO:0005006)
0.0 0.1 GO:0042808 obsolete neuronal Cdc2-like kinase binding(GO:0042808)
0.0 0.1 GO:0035514 DNA demethylase activity(GO:0035514) DNA-N1-methyladenine dioxygenase activity(GO:0043734)
0.0 0.1 GO:0050693 LBD domain binding(GO:0050693)
0.0 0.2 GO:0030297 transmembrane receptor protein tyrosine kinase activator activity(GO:0030297)
0.0 0.1 GO:0050431 transforming growth factor beta binding(GO:0050431)
0.0 0.1 GO:0033130 acetylcholine receptor binding(GO:0033130)
0.0 0.2 GO:0070063 RNA polymerase binding(GO:0070063)
0.0 0.2 GO:0004028 3-chloroallyl aldehyde dehydrogenase activity(GO:0004028)
0.0 0.5 GO:0005523 tropomyosin binding(GO:0005523)
0.0 0.1 GO:0005030 neurotrophin receptor activity(GO:0005030)
0.0 0.1 GO:0016941 natriuretic peptide receptor activity(GO:0016941)
0.0 0.0 GO:0070052 collagen V binding(GO:0070052)
0.0 0.2 GO:0043237 laminin-1 binding(GO:0043237)
0.0 0.1 GO:0050220 prostaglandin-E synthase activity(GO:0050220)
0.0 0.7 GO:0050840 extracellular matrix binding(GO:0050840)
0.0 0.1 GO:0004720 protein-lysine 6-oxidase activity(GO:0004720)
0.0 0.2 GO:0005021 vascular endothelial growth factor-activated receptor activity(GO:0005021)
0.0 0.1 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0 0.1 GO:0048185 activin binding(GO:0048185)
0.0 0.1 GO:0003872 6-phosphofructokinase activity(GO:0003872)
0.0 0.1 GO:0055103 ligase regulator activity(GO:0055103) ubiquitin-protein transferase regulator activity(GO:0055106)
0.0 0.1 GO:0017159 pantetheine hydrolase activity(GO:0017159)
0.0 0.1 GO:0042156 obsolete zinc-mediated transcriptional activator activity(GO:0042156)
0.0 0.1 GO:0005148 prolactin receptor binding(GO:0005148)
0.0 0.1 GO:0042285 UDP-xylosyltransferase activity(GO:0035252) xylosyltransferase activity(GO:0042285)
0.0 0.1 GO:0015183 L-aspartate transmembrane transporter activity(GO:0015183)
0.0 0.1 GO:0001601 peptide YY receptor activity(GO:0001601)
0.0 0.1 GO:0004758 serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
0.0 0.2 GO:0042153 obsolete RPTP-like protein binding(GO:0042153)
0.0 0.2 GO:0004859 phospholipase inhibitor activity(GO:0004859)
0.0 0.1 GO:0001515 opioid peptide activity(GO:0001515)
0.0 0.1 GO:0033765 steroid dehydrogenase activity, acting on the CH-CH group of donors(GO:0033765)
0.0 0.2 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.0 0.1 GO:0002060 purine nucleobase binding(GO:0002060)
0.0 0.2 GO:0070402 NADPH binding(GO:0070402)
0.0 0.3 GO:0043498 obsolete cell surface binding(GO:0043498)
0.0 0.2 GO:0030371 translation repressor activity(GO:0030371)
0.0 0.1 GO:0001758 retinal dehydrogenase activity(GO:0001758)
0.0 0.1 GO:0047499 calcium-independent phospholipase A2 activity(GO:0047499)
0.0 0.1 GO:0008327 methyl-CpG binding(GO:0008327)
0.0 0.2 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.0 0.0 GO:0043184 vascular endothelial growth factor receptor 2 binding(GO:0043184)
0.0 0.1 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.0 0.1 GO:0004937 alpha1-adrenergic receptor activity(GO:0004937)
0.0 0.1 GO:0045499 chemorepellent activity(GO:0045499)
0.0 0.1 GO:0031545 procollagen-proline 4-dioxygenase activity(GO:0004656) peptidyl-proline 4-dioxygenase activity(GO:0031545)
0.0 0.1 GO:0030020 extracellular matrix structural constituent conferring tensile strength(GO:0030020)
0.0 0.1 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.0 0.1 GO:0044020 histone methyltransferase activity (H4-R3 specific)(GO:0044020)
0.0 0.1 GO:0004924 oncostatin-M receptor activity(GO:0004924)
0.0 0.2 GO:0008271 secondary active sulfate transmembrane transporter activity(GO:0008271)
0.0 0.1 GO:0015065 uridine nucleotide receptor activity(GO:0015065) G-protein coupled pyrimidinergic nucleotide receptor activity(GO:0071553)
0.0 0.1 GO:0004948 calcitonin receptor activity(GO:0004948)
0.0 0.0 GO:0048018 receptor agonist activity(GO:0048018)
0.0 0.1 GO:0008046 axon guidance receptor activity(GO:0008046)
0.0 0.1 GO:0001591 dopamine neurotransmitter receptor activity, coupled via Gi/Go(GO:0001591)
0.0 0.1 GO:0034186 apolipoprotein A-I binding(GO:0034186)
0.0 0.1 GO:0008294 calcium- and calmodulin-responsive adenylate cyclase activity(GO:0008294)
0.0 0.2 GO:0016813 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
0.0 0.3 GO:0005024 transforming growth factor beta-activated receptor activity(GO:0005024)
0.0 0.1 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity(GO:0004694)
0.0 0.2 GO:0005112 Notch binding(GO:0005112)
0.0 0.1 GO:0004470 malic enzyme activity(GO:0004470)
0.0 0.1 GO:0046965 retinoid X receptor binding(GO:0046965)
0.0 0.1 GO:0042910 xenobiotic-transporting ATPase activity(GO:0008559) xenobiotic transporter activity(GO:0042910)
0.0 0.1 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
0.0 0.1 GO:0036137 kynurenine-oxoglutarate transaminase activity(GO:0016212) kynurenine aminotransferase activity(GO:0036137)
0.0 0.1 GO:0008475 procollagen-lysine 5-dioxygenase activity(GO:0008475)
0.0 0.1 GO:0031821 G-protein coupled serotonin receptor binding(GO:0031821)
0.0 0.1 GO:0004862 cAMP-dependent protein kinase inhibitor activity(GO:0004862)
0.0 0.1 GO:0070696 transmembrane receptor protein serine/threonine kinase binding(GO:0070696)
0.0 0.1 GO:0004024 alcohol dehydrogenase activity, zinc-dependent(GO:0004024)
0.0 0.1 GO:0047115 trans-1,2-dihydrobenzene-1,2-diol dehydrogenase activity(GO:0047115)
0.0 0.1 GO:0005042 netrin receptor activity(GO:0005042)
0.0 0.1 GO:0030274 LIM domain binding(GO:0030274)
0.0 0.1 GO:0044390 ubiquitin conjugating enzyme binding(GO:0031624) ubiquitin-like protein conjugating enzyme binding(GO:0044390)
0.0 0.1 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.0 0.1 GO:0031994 insulin-like growth factor I binding(GO:0031994)
0.0 0.1 GO:0015254 glycerol channel activity(GO:0015254)
0.0 0.0 GO:0047045 testosterone 17-beta-dehydrogenase (NADP+) activity(GO:0047045)
0.0 0.1 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.0 0.1 GO:0034648 histone demethylase activity (H3-K4 specific)(GO:0032453) histone demethylase activity (H3-dimethyl-K4 specific)(GO:0034648)
0.0 0.1 GO:0005152 interleukin-1 receptor antagonist activity(GO:0005152)
0.0 0.0 GO:0003876 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.0 0.1 GO:0008312 7S RNA binding(GO:0008312)
0.0 0.0 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.0 0.0 GO:0004607 phosphatidylcholine-sterol O-acyltransferase activity(GO:0004607)
0.0 0.1 GO:0016847 1-aminocyclopropane-1-carboxylate synthase activity(GO:0016847)
0.0 0.1 GO:0005110 frizzled-2 binding(GO:0005110)
0.0 0.3 GO:0031683 G-protein beta/gamma-subunit complex binding(GO:0031683)
0.0 0.3 GO:0005001 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.0 0.0 GO:0016909 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.0 0.1 GO:0015037 peptide disulfide oxidoreductase activity(GO:0015037)
0.0 0.1 GO:0004597 peptide-aspartate beta-dioxygenase activity(GO:0004597)
0.0 0.1 GO:0048019 receptor antagonist activity(GO:0048019)
0.0 0.0 GO:0003953 NAD+ nucleosidase activity(GO:0003953)
0.0 0.1 GO:0016832 aldehyde-lyase activity(GO:0016832)
0.0 0.1 GO:0004849 uridine kinase activity(GO:0004849)
0.0 0.0 GO:0008607 phosphorylase kinase regulator activity(GO:0008607)
0.0 0.1 GO:0001968 fibronectin binding(GO:0001968)
0.0 0.0 GO:0005010 insulin-like growth factor-activated receptor activity(GO:0005010)
0.0 0.0 GO:0030343 vitamin D3 25-hydroxylase activity(GO:0030343) vitamin D 25-hydroxylase activity(GO:0070643)
0.0 0.1 GO:0005123 death receptor binding(GO:0005123)
0.0 0.1 GO:0019238 cyclohydrolase activity(GO:0019238)
0.0 0.0 GO:0048495 Roundabout binding(GO:0048495)
0.0 0.0 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.0 0.1 GO:0047429 nucleoside-triphosphate diphosphatase activity(GO:0047429)
0.0 0.0 GO:0004992 platelet activating factor receptor activity(GO:0004992)
0.0 0.2 GO:0015269 calcium-activated potassium channel activity(GO:0015269)
0.0 0.0 GO:0004461 lactose synthase activity(GO:0004461)
0.0 0.3 GO:0016769 transferase activity, transferring nitrogenous groups(GO:0016769)
0.0 0.0 GO:0030023 extracellular matrix constituent conferring elasticity(GO:0030023) structural molecule activity conferring elasticity(GO:0097493)
0.0 0.2 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.0 0.1 GO:0046790 virion binding(GO:0046790)
0.0 0.1 GO:0032137 guanine/thymine mispair binding(GO:0032137)
0.0 0.6 GO:0004714 transmembrane receptor protein tyrosine kinase activity(GO:0004714)
0.0 0.1 GO:0004305 ethanolamine kinase activity(GO:0004305)
0.0 0.0 GO:0005534 galactose binding(GO:0005534)
0.0 0.2 GO:0035035 histone acetyltransferase binding(GO:0035035)
0.0 0.0 GO:0070996 type 1 melanocortin receptor binding(GO:0070996)
0.0 0.1 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.0 0.1 GO:0050656 3'-phosphoadenosine 5'-phosphosulfate binding(GO:0050656)
0.0 0.1 GO:0004128 cytochrome-b5 reductase activity, acting on NAD(P)H(GO:0004128)
0.0 0.1 GO:0000339 RNA cap binding(GO:0000339)
0.0 0.1 GO:0003846 2-acylglycerol O-acyltransferase activity(GO:0003846)
0.0 0.0 GO:0015193 L-proline transmembrane transporter activity(GO:0015193)
0.0 0.0 GO:0005172 vascular endothelial growth factor receptor binding(GO:0005172)
0.0 0.1 GO:0016018 cyclosporin A binding(GO:0016018)
0.0 0.0 GO:0050998 nitric-oxide synthase binding(GO:0050998)
0.0 0.1 GO:0070290 N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.0 0.7 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 0.0 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.0 0.1 GO:0022821 potassium ion antiporter activity(GO:0022821)
0.0 0.1 GO:0015220 choline transmembrane transporter activity(GO:0015220)
0.0 0.0 GO:0004351 glutamate decarboxylase activity(GO:0004351)
0.0 0.0 GO:0004515 nicotinamide-nucleotide adenylyltransferase activity(GO:0000309) nicotinate-nucleotide adenylyltransferase activity(GO:0004515)
0.0 0.0 GO:0048027 mRNA 5'-UTR binding(GO:0048027)
0.0 0.1 GO:0070628 proteasome binding(GO:0070628)
0.0 0.0 GO:0004616 phosphogluconate dehydrogenase (decarboxylating) activity(GO:0004616)
0.0 0.1 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.0 0.1 GO:0016500 protein-hormone receptor activity(GO:0016500)
0.0 0.0 GO:0003829 beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity(GO:0003829)
0.0 0.0 GO:0003956 NAD(P)+-protein-arginine ADP-ribosyltransferase activity(GO:0003956)
0.0 0.0 GO:0004032 alditol:NADP+ 1-oxidoreductase activity(GO:0004032)
0.0 0.1 GO:0042800 histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.0 0.2 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.0 0.0 GO:0035198 miRNA binding(GO:0035198)
0.0 0.0 GO:0045294 alpha-catenin binding(GO:0045294)
0.0 0.0 GO:0004047 aminomethyltransferase activity(GO:0004047)
0.0 0.1 GO:0010853 cyclase activator activity(GO:0010853) guanylate cyclase activator activity(GO:0030250)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.1 PID GLYPICAN 1PATHWAY Glypican 1 network
0.1 0.6 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.0 0.0 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.0 0.5 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.0 0.2 PID LYSOPHOSPHOLIPID PATHWAY LPA receptor mediated events
0.0 0.0 PID EPHRINB REV PATHWAY Ephrin B reverse signaling
0.0 0.4 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.0 1.0 NABA COLLAGENS Genes encoding collagen proteins
0.0 0.0 PID IGF1 PATHWAY IGF1 pathway
0.0 0.3 PID SYNDECAN 1 PATHWAY Syndecan-1-mediated signaling events
0.0 0.2 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.0 0.1 PID NETRIN PATHWAY Netrin-mediated signaling events
0.0 0.5 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.0 0.0 ST JAK STAT PATHWAY Jak-STAT Pathway
0.0 0.2 ST G ALPHA S PATHWAY G alpha s Pathway
0.0 0.0 PID REELIN PATHWAY Reelin signaling pathway
0.0 0.3 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events
0.0 0.3 PID S1P S1P2 PATHWAY S1P2 pathway
0.0 0.2 PID LPA4 PATHWAY LPA4-mediated signaling events
0.0 0.1 PID FOXO PATHWAY FoxO family signaling
0.0 0.0 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.0 0.5 PID INTEGRIN1 PATHWAY Beta1 integrin cell surface interactions
0.0 0.5 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.0 0.7 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.0 0.1 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.0 0.0 PID ER NONGENOMIC PATHWAY Plasma membrane estrogen receptor signaling
0.0 0.2 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.0 0.5 PID RHOA REG PATHWAY Regulation of RhoA activity
0.0 0.1 PID AJDISS 2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.0 0.3 PID WNT SIGNALING PATHWAY Wnt signaling network
0.0 0.2 PID SYNDECAN 2 PATHWAY Syndecan-2-mediated signaling events
0.0 0.2 PID UPA UPAR PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.0 0.4 PID HNF3A PATHWAY FOXA1 transcription factor network
0.0 0.0 SA G1 AND S PHASES Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition.

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.7 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.1 0.1 REACTOME PECAM1 INTERACTIONS Genes involved in PECAM1 interactions
0.0 0.0 REACTOME G ALPHA Z SIGNALLING EVENTS Genes involved in G alpha (z) signalling events
0.0 0.1 REACTOME ADP SIGNALLING THROUGH P2RY12 Genes involved in ADP signalling through P2Y purinoceptor 12
0.0 0.1 REACTOME SIGNALING BY CONSTITUTIVELY ACTIVE EGFR Genes involved in Signaling by constitutively active EGFR
0.0 0.5 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.0 0.8 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.0 0.0 REACTOME SIGNALING BY ILS Genes involved in Signaling by Interleukins
0.0 0.2 REACTOME RETROGRADE NEUROTROPHIN SIGNALLING Genes involved in Retrograde neurotrophin signalling
0.0 0.0 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS Genes involved in Synthesis of bile acids and bile salts
0.0 0.7 REACTOME MYOGENESIS Genes involved in Myogenesis
0.0 0.0 REACTOME RNA POL I PROMOTER OPENING Genes involved in RNA Polymerase I Promoter Opening
0.0 0.3 REACTOME ADENYLATE CYCLASE INHIBITORY PATHWAY Genes involved in Adenylate cyclase inhibitory pathway
0.0 0.1 REACTOME INFLUENZA VIRAL RNA TRANSCRIPTION AND REPLICATION Genes involved in Influenza Viral RNA Transcription and Replication
0.0 0.2 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.0 0.7 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.0 0.3 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.0 0.2 REACTOME GAP JUNCTION DEGRADATION Genes involved in Gap junction degradation
0.0 0.2 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.0 1.0 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.0 0.2 REACTOME A TETRASACCHARIDE LINKER SEQUENCE IS REQUIRED FOR GAG SYNTHESIS Genes involved in A tetrasaccharide linker sequence is required for GAG synthesis
0.0 0.0 REACTOME PD1 SIGNALING Genes involved in PD-1 signaling
0.0 0.1 REACTOME ANDROGEN BIOSYNTHESIS Genes involved in Androgen biosynthesis
0.0 0.2 REACTOME ACYL CHAIN REMODELLING OF PI Genes involved in Acyl chain remodelling of PI
0.0 0.3 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.0 0.2 REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.0 0.1 REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.0 0.1 REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.0 0.3 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.0 0.1 REACTOME SIGNALING BY ACTIVATED POINT MUTANTS OF FGFR1 Genes involved in Signaling by activated point mutants of FGFR1
0.0 0.1 REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.0 0.3 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.0 0.2 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.0 0.1 REACTOME SIGNAL ATTENUATION Genes involved in Signal attenuation
0.0 0.1 REACTOME DCC MEDIATED ATTRACTIVE SIGNALING Genes involved in DCC mediated attractive signaling
0.0 0.1 REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.0 0.2 REACTOME PEPTIDE HORMONE BIOSYNTHESIS Genes involved in Peptide hormone biosynthesis
0.0 0.1 REACTOME PURINE CATABOLISM Genes involved in Purine catabolism