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ENCODE: H3K4me1 ChIP-Seq of primary human cells
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Results for PAX3

Z-value: 1.17

Motif logo

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Transcription factors associated with PAX3

Gene Symbol Gene ID Gene Info
PAX3
ENSG00000135903.14 paired box 3

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE Gene Distance Association probability Pearson corr. coef. P-value Plot
chr2_223164777_223164928PAX311370.4430020.561.1e-01Click!
chr2_223163781_223163932PAX31410.923324-0.521.6e-01Click!
chr2_223164524_223164675PAX38840.5275230.462.1e-01Click!
chr2_223164169_223164320PAX35290.701476-0.343.7e-01Click!
chr2_223163217_223163499PAX31070.861826-0.068.7e-01Click!

Activity of the PAX3 motif across conditions

Conditions sorted by the z-value of the PAX3 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE) Target Score Top associated gene Gene Info Distance of CRE to TSS CRE/Gene association probability
chr11_44630927_44631130 0.40 RP11-58K22.4
1377
 0.42
chr12_56210624_56211230 0.36 SARNP
 SAP domain containing ribonucleoprotein
 566
 0.44
chr10_111972940_111973241 0.34 MXI1
 MAX interactor 1, dimerization protein
 3101
 0.27
chr1_100504806_100504996 0.33 HIAT1
 hippocampus abundant transcript 1
 1248
 0.37
chr5_100188313_100188787 0.31 ENSG00000221263
 .
 36281
 0.2
chr3_46005698_46005849 0.31 FYCO1
 FYVE and coiled-coil domain containing 1
 5620
 0.18
chr2_113943413_113943847 0.29 PSD4
 pleckstrin and Sec7 domain containing 4
 10227
 0.14
chr8_103389332_103389537 0.29 ENSG00000238533
 .
 11429
 0.19
chr9_95817754_95818259 0.28 SUSD3
 sushi domain containing 3
 2983
 0.24
chr9_98513414_98513617 0.27 DKFZP434H0512
 Protein LOC100506667; Putative uncharacterized protein DKFZp434H0512
 21090
 0.24
chr14_99399270_99399624 0.27 C14orf177
 chromosome 14 open reading frame 177
 221490
 0.02
chr11_587585_588264 0.27 PHRF1
 PHD and ring finger domains 1
 11403
 0.07
chr7_37391286_37391569 0.26 ENSG00000222869
 .
 680
 0.66
chr16_84647052_84647203 0.26 COTL1
 coactosin-like 1 (Dictyostelium)
 4538
 0.2
chr11_128588934_128589085 0.26 SENCR
 smooth muscle and endothelial cell enriched migration/differentiation-associated long non-coding RNA
 23091
 0.17
chr1_181006045_181006268 0.26 MR1
 major histocompatibility complex, class I-related
 3017
 0.23
chr3_71535527_71535739 0.26 ENSG00000221264
 .
 55607
 0.13
chr14_52407231_52407382 0.26 RP11-463J10.2
 Uncharacterized protein
 22017
 0.13
chr15_45027905_45028453 0.25 TRIM69
 tripartite motif containing 69
 381
 0.83
chr19_57182581_57182785 0.25 ZNF835
 zinc finger protein 835
 445
 0.78
chr6_24930509_24931296 0.24 FAM65B
 family with sequence similarity 65, member B
 5286
 0.26
chr16_66624775_66624926 0.24 RP11-403P17.2
10231
 0.1
chr8_82006436_82006760 0.24 PAG1
 phosphoprotein associated with glycosphingolipid microdomains 1
 17705
 0.27
chr13_111526304_111526455 0.24 LINC00346
 long intergenic non-protein coding RNA 346
 4217
 0.23
chr22_40326443_40326594 0.23 GRAP2
 GRB2-related adaptor protein 2
 3877
 0.21
chr2_137038474_137038625 0.23 ENSG00000251976
 .
 109353
 0.07
chr20_24962019_24962324 0.23 ENSG00000207355
 .
 7364
 0.19
chr14_93115762_93116231 0.23 RIN3
 Ras and Rab interactor 3
 2850
 0.36
chr17_38771222_38771726 0.23 SMARCE1
 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 1
 17068
 0.14
chr7_157182070_157182377 0.22 DNAJB6
 DnaJ (Hsp40) homolog, subfamily B, member 6
 49708
 0.15
chr19_10870035_10870582 0.22 ENSG00000265879
 .
 20622
 0.11
chr13_24824909_24825522 0.22 SPATA13
 spermatogenesis associated 13
 617
 0.7
chr2_233184314_233184699 0.22 DIS3L2
 DIS3 mitotic control homolog (S. cerevisiae)-like 2
 14147
 0.18
chr2_127419346_127420030 0.22 GYPC
 glycophorin C (Gerbich blood group)
 5928
 0.29
chrX_135742690_135742856 0.22 CD40LG
 CD40 ligand
 12387
 0.17
chr2_158286835_158286986 0.22 CYTIP
 cytohesin 1 interacting protein
 9016
 0.22
chr5_1503386_1503697 0.22 LPCAT1
 lysophosphatidylcholine acyltransferase 1
 20551
 0.2
chrX_135842036_135842388 0.22 ARHGEF6
 Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6
 7290
 0.19
chr11_85411371_85411865 0.22 CCDC89
 coiled-coil domain containing 89
 14298
 0.15
chr19_4115268_4115780 0.22 MAP2K2
 mitogen-activated protein kinase kinase 2
 8590
 0.13
chr7_5461177_5461902 0.22 TNRC18
 trinucleotide repeat containing 18
 1638
 0.24
chr2_235392806_235393340 0.22 ARL4C
 ADP-ribosylation factor-like 4C
 12171
 0.32
chr17_8771075_8771247 0.21 PIK3R6
 phosphoinositide-3-kinase, regulatory subunit 6
 167
 0.96
chr2_136872566_136873100 0.21 CXCR4
 chemokine (C-X-C motif) receptor 4
 980
 0.68
chr20_1602531_1602783 0.21 RP4-576H24.4
 Uncharacterized protein
 2002
 0.21
chr12_72043386_72043537 0.21 ENSG00000212461
 .
 10326
 0.16
chr2_198157391_198157702 0.21 ANKRD44-IT1
 ANKRD44 intronic transcript 1 (non-protein coding)
 9697
 0.17
chrX_78427887_78428156 0.21 GPR174
 G protein-coupled receptor 174
 1552
 0.57
chr12_116651690_116651896 0.21 RP11-115H15.2
32693
 0.16
chr2_145459727_145459992 0.21 ZEB2
 zinc finger E-box binding homeobox 2
 181238
 0.03
chr14_23939099_23939325 0.21 NGDN
 neuroguidin, EIF4E binding protein
 47
 0.96
chr2_54806316_54807000 0.20 SPTBN1
 spectrin, beta, non-erythrocytic 1
 21127
 0.18
chr19_55009447_55009893 0.20 LAIR2
 leukocyte-associated immunoglobulin-like receptor 2
 570
 0.6
chr4_15022705_15022879 0.20 CPEB2
 cytoplasmic polyadenylation element binding protein 2
 17232
 0.27
chr10_111775510_111775661 0.20 ADD3
 adducin 3 (gamma)
 7863
 0.21
chr13_48718601_48718752 0.20 MED4
 mediator complex subunit 4
 49409
 0.14
chr6_39079511_39079662 0.20 SAYSD1
 SAYSVFN motif domain containing 1
 2238
 0.39
chr7_104696089_104696325 0.20 KMT2E
 lysine (K)-specific methyltransferase 2E
 41299
 0.12
chr9_132700843_132701237 0.20 RP11-409K20.6
5225
 0.21
chr16_84792149_84792512 0.20 USP10
 ubiquitin specific peptidase 10
 9541
 0.21
chr19_33666219_33666370 0.20 ENSG00000264355
 .
 1684
 0.23
chr18_29628950_29629327 0.20 ENSG00000265063
 .
 11814
 0.14
chr2_158325492_158325945 0.20 CYTIP
 cytohesin 1 interacting protein
 19623
 0.21
chr10_32629803_32629954 0.20 RP11-135A24.4
5549
 0.14
chr1_100887321_100887588 0.20 ENSG00000216067
 .
 43123
 0.14
chr8_81477973_81478412 0.20 ENSG00000223327
 .
 19816
 0.2
chr21_36414924_36415236 0.20 RUNX1
 runt-related transcription factor 1
 6382
 0.34
chr7_50448999_50449150 0.20 ENSG00000200815
 .
 54004
 0.14
chr10_11186185_11186414 0.19 CELF2
 CUGBP, Elav-like family member 2
 20694
 0.19
chr17_29632882_29633122 0.19 EVI2B
 ecotropic viral integration site 2B
 8100
 0.13
chr12_6535038_6535392 0.19 CD27
 CD27 molecule
 18818
 0.09
chr6_143177440_143177974 0.19 HIVEP2
 human immunodeficiency virus type I enhancer binding protein 2
 19523
 0.26
chrX_153947159_153947493 0.19 GAB3
 GRB2-associated binding protein 3
 32006
 0.1
chr12_15130915_15131069 0.19 PDE6H
 phosphodiesterase 6H, cGMP-specific, cone, gamma
 5036
 0.2
chr4_166249313_166249610 0.19 MSMO1
 methylsterol monooxygenase 1
 382
 0.88
chr11_122597336_122597788 0.19 ENSG00000239079
 .
 543
 0.83
chr10_5489002_5489404 0.19 NET1
 neuroepithelial cell transforming 1
 629
 0.71
chr12_102437834_102438009 0.19 CCDC53
 coiled-coil domain containing 53
 1976
 0.32
chr5_53840666_53840817 0.19 SNX18
 sorting nexin 18
 27148
 0.24
chr1_167620769_167621002 0.19 RP3-455J7.4
20974
 0.18
chr12_56420621_56420772 0.19 IKZF4
 IKAROS family zinc finger 4 (Eos)
 5596
 0.09
chr1_154127490_154127791 0.19 NUP210L
 nucleoporin 210kDa-like
 48
 0.95
chr11_96069523_96069674 0.19 ENSG00000266192
 .
 5004
 0.22
chr6_96034444_96034595 0.19 MANEA
 mannosidase, endo-alpha
 9100
 0.25
chr6_109340701_109340852 0.19 SESN1
 sestrin 1
 10018
 0.19
chr16_89850957_89851182 0.19 FANCA
 Fanconi anemia, complementation group A
 31974
 0.1
chr17_4081322_4081473 0.19 ENSG00000251812
 .
 8224
 0.12
chr21_44203039_44203232 0.19 AP001627.1
41267
 0.15
chr2_198044307_198044458 0.19 ANKRD44
 ankyrin repeat domain 44
 7451
 0.23
chr14_73002896_73003047 0.19 RGS6
 regulator of G-protein signaling 6
 76594
 0.12
chr5_14594455_14594804 0.19 FAM105A
 family with sequence similarity 105, member A
 12745
 0.24
chr11_6742741_6742892 0.19 GVINP1
 GTPase, very large interferon inducible pseudogene 1
 295
 0.86
chr9_123551480_123551631 0.18 FBXW2
 F-box and WD repeat domain containing 2
 4100
 0.22
chr6_167366901_167367052 0.18 RP11-514O12.4
2636
 0.2
chr1_206751930_206752246 0.18 RASSF5
 Ras association (RalGDS/AF-6) domain family member 5
 21595
 0.14
chr20_31560742_31561149 0.18 EFCAB8
 EF-hand calcium binding domain 8
 13294
 0.15
chr3_187971650_187971801 0.18 LPP
 LIM domain containing preferred translocation partner in lipoma
 14073
 0.27
chr14_68751578_68751902 0.18 ENSG00000243546
 .
 48484
 0.17
chr6_108145921_108146601 0.18 SCML4
 sex comb on midleg-like 4 (Drosophila)
 740
 0.76
chr3_4536511_4536662 0.18 ITPR1
 inositol 1,4,5-trisphosphate receptor, type 1
 1352
 0.39
chr6_149397702_149397853 0.18 RP11-162J8.3
44068
 0.17
chr13_74803959_74804110 0.18 ENSG00000206617
 .
 59317
 0.15
chr11_44992839_44992990 0.18 TP53I11
 tumor protein p53 inducible protein 11
 20306
 0.24
chr6_112071150_112071301 0.18 FYN
 FYN oncogene related to SRC, FGR, YES
 9092
 0.27
chr1_203733638_203733972 0.18 LAX1
 lymphocyte transmembrane adaptor 1
 499
 0.77
chr9_117126749_117127269 0.18 AKNA
 AT-hook transcription factor
 12235
 0.19
chr7_114646115_114646266 0.18 MDFIC
 MyoD family inhibitor domain containing
 72266
 0.13
chr12_9449062_9449213 0.18 ENSG00000212440
 .
 9719
 0.19
chr1_167791837_167791988 0.18 RP1-313L4.3
2268
 0.35
chr20_8370040_8370204 0.18 PLCB1-IT1
 PLCB1 intronic transcript 1 (non-protein coding)
 140750
 0.05
chr16_28584510_28584773 0.18 CCDC101
 coiled-coil domain containing 101
 17065
 0.11
chr8_67518848_67519042 0.18 MYBL1
 v-myb avian myeloblastosis viral oncogene homolog-like 1
 6197
 0.19
chr13_47195525_47195676 0.18 LRCH1
 leucine-rich repeats and calponin homology (CH) domain containing 1
 58371
 0.15
chr13_36463957_36464108 0.18 DCLK1
 doublecortin-like kinase 1
 34253
 0.24
chrX_8582050_8582201 0.18 KAL1
 Kallmann syndrome 1 sequence
 118102
 0.06
chr1_1076072_1076302 0.18 C1orf159
 chromosome 1 open reading frame 159
 24446
 0.07
chr15_63838577_63838728 0.18 USP3
 ubiquitin specific peptidase 3
 1828
 0.36
chr19_3784822_3785395 0.18 MATK
 megakaryocyte-associated tyrosine kinase
 537
 0.63
chr18_21589322_21589666 0.18 TTC39C
 tetratricopeptide repeat domain 39C
 4890
 0.2
chr11_66058924_66059101 0.18 TMEM151A
 transmembrane protein 151A
 329
 0.67
chr1_22438380_22438623 0.18 WNT4
 wingless-type MMTV integration site family, member 4
 17843
 0.16
chr14_100560569_100560771 0.18 EVL
 Enah/Vasp-like
 2614
 0.2
chr8_97163146_97163297 0.18 GDF6
 growth differentiation factor 6
 9799
 0.25
chr9_91926652_91926816 0.18 ENSG00000265112
 .
 406
 0.61
chr8_142413099_142413596 0.17 CTD-3064M3.4
10673
 0.12
chr16_53550821_53550972 0.17 AKTIP
 AKT interacting protein
 12573
 0.21
chr10_51503867_51504211 0.17 AGAP7
 ArfGAP with GTPase domain, ankyrin repeat and PH domain 7
 17712
 0.18
chr21_29748389_29748540 0.17 ENSG00000251894
 .
 367066
 0.01
chr3_169759548_169759699 0.17 GPR160
 G protein-coupled receptor 160
 3697
 0.18
chr13_76341667_76341947 0.17 LMO7
 LIM domain 7
 7010
 0.28
chr16_30918804_30919130 0.17 CTF1
 cardiotrophin 1
 11008
 0.07
chr6_26385342_26385556 0.17 BTN2A2
 butyrophilin, subfamily 2, member A2
 1788
 0.2
chr16_81502646_81502945 0.17 CMIP
 c-Maf inducing protein
 24020
 0.23
chr7_72857019_72857170 0.17 FZD9
 frizzled family receptor 9
 8985
 0.17
chr18_3264027_3264245 0.17 MYL12B
 myosin, light chain 12B, regulatory
 1182
 0.39
chr16_88860278_88860577 0.17 PIEZO1
 piezo-type mechanosensitive ion channel component 1
 8808
 0.09
chr5_102809102_102809289 0.17 NUDT12
 nudix (nucleoside diphosphate linked moiety X)-type motif 12
 89295
 0.1
chr5_133439080_133439473 0.17 TCF7
 transcription factor 7 (T-cell specific, HMG-box)
 11126
 0.22
chr9_80031789_80031940 0.17 VPS13A
 vacuolar protein sorting 13 homolog A (S. cerevisiae)
 10980
 0.26
chr5_130725391_130725800 0.17 CDC42SE2
 CDC42 small effector 2
 4296
 0.34
chr1_155939676_155940356 0.17 ARHGEF2
 Rho/Rac guanine nucleotide exchange factor (GEF) 2
 496
 0.63
chr19_53603309_53603460 0.17 ZNF160
 zinc finger protein 160
 3220
 0.18
chr4_4945545_4945811 0.17 ENSG00000200761
 .
 22887
 0.22
chr19_47448802_47448953 0.17 ENSG00000252071
 .
 2669
 0.25
chr5_169232621_169233022 0.17 CTB-37A13.1
26452
 0.22
chr2_145279022_145279173 0.17 ZEB2
 zinc finger E-box binding homeobox 2
 476
 0.7
chr22_46732320_46732471 0.17 TRMU
 tRNA 5-methylaminomethyl-2-thiouridylate methyltransferase
 576
 0.76
chr21_32508291_32508442 0.17 TIAM1
 T-cell lymphoma invasion and metastasis 1
 5827
 0.3
chr12_65109271_65109422 0.17 AC025262.1
 Mesenchymal stem cell protein DSC96; Uncharacterized protein
 19017
 0.13
chr4_1856936_1857463 0.17 LETM1
 leucine zipper-EF-hand containing transmembrane protein 1
 775
 0.59
chr12_116999316_116999521 0.17 MAP1LC3B2
 microtubule-associated protein 1 light chain 3 beta 2
 2232
 0.43
chr2_68615070_68615679 0.17 AC015969.3
22658
 0.16
chr15_38847278_38847550 0.17 RASGRP1
 RAS guanyl releasing protein 1 (calcium and DAG-regulated)
 4869
 0.21
chr19_54885852_54886183 0.17 LAIR1
 leukocyte-associated immunoglobulin-like receptor 1
 3852
 0.13
chr18_43266623_43266884 0.17 SLC14A2
 solute carrier family 14 (urea transporter), member 2
 20646
 0.17
chr3_67789239_67789462 0.17 SUCLG2
 succinate-CoA ligase, GDP-forming, beta subunit
 84312
 0.1
chr18_74190035_74190186 0.17 ZNF516
 zinc finger protein 516
 12625
 0.17
chr17_2577470_2577621 0.17 PAFAH1B1
 platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa)
 3983
 0.14
chr2_197114023_197114207 0.17 AC020571.3
10633
 0.19
chr2_24843650_24843801 0.17 NCOA1
 nuclear receptor coactivator 1
 36315
 0.16
chr15_38825178_38825329 0.17 RP11-275I4.1
8982
 0.17
chr4_102210034_102210185 0.17 ENSG00000221265
 .
 41462
 0.16
chr14_107179456_107179744 0.17 IGHV2-70
 immunoglobulin heavy variable 2-70
 262
 0.7
chr2_167467162_167467351 0.16 SCN7A
 sodium channel, voltage-gated, type VII, alpha subunit
 116499
 0.07
chr2_234178246_234178416 0.16 ENSG00000252010
 .
 6042
 0.15
chr8_61730824_61730975 0.16 RP11-33I11.2
8734
 0.29
chr20_1655973_1656235 0.16 ENSG00000242348
 .
 9098
 0.16
chr1_229194417_229194588 0.16 RP5-1061H20.5
168807
 0.03
chr15_62148457_62148639 0.16 RP11-16B9.1
21597
 0.23
chr20_21537646_21537821 0.16 NKX2-2
 NK2 homeobox 2
 43069
 0.16
chr17_30479138_30479373 0.16 AC090616.2
 Uncharacterized protein
 9101
 0.13
chr5_88030594_88030850 0.16 CTC-467M3.2
42254
 0.16
chr2_173375155_173375356 0.16 AC093818.1
1983
 0.3
chr6_24918748_24919201 0.16 FAM65B
 family with sequence similarity 65, member B
 7779
 0.24
chr11_63487782_63487933 0.16 RTN3
 reticulon 3
 38812
 0.11
chr8_39797416_39797641 0.16 IDO2
 indoleamine 2,3-dioxygenase 2
 5054
 0.18
chrX_13077716_13078009 0.16 FAM9C
 family with sequence similarity 9, member C
 15061
 0.26
chr7_139465607_139465758 0.16 HIPK2
 homeodomain interacting protein kinase 2
 11835
 0.23
chr4_36192264_36192495 0.16 ARAP2
 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
 19988
 0.24
chr3_176940409_176940560 0.16 TBL1XR1
 transducin (beta)-like 1 X-linked receptor 1
 25223
 0.24
chr8_129664945_129665222 0.16 ENSG00000221351
 .
 166957
 0.04
chr2_99120667_99121116 0.16 INPP4A
 inositol polyphosphate-4-phosphatase, type I, 107kDa
 15621
 0.23
chr5_16608595_16608746 0.16 RP11-260E18.1
7365
 0.19
chr1_66831872_66832123 0.16 PDE4B
 phosphodiesterase 4B, cAMP-specific
 11932
 0.3
chr7_8054995_8055386 0.16 AC006042.7
45656
 0.13
chr17_72516903_72517217 0.16 CD300LB
 CD300 molecule-like family member b
 10545
 0.14
chr7_77614950_77615101 0.16 RP5-1185I7.1
4676
 0.32
chr2_12410968_12411119 0.16 ENSG00000264089
 .
 71787
 0.13
chr11_6742912_6743421 0.16 GVINP1
 GTPase, very large interferon inducible pseudogene 1
 55
 0.96
chr4_85672938_85673089 0.16 WDFY3
 WD repeat and FYVE domain containing 3
 18398
 0.22
chr17_78622247_78622398 0.16 RPTOR
 regulatory associated protein of MTOR, complex 1
 103054
 0.06
chr1_42924324_42924527 0.16 PPCS
 phosphopantothenoylcysteine synthetase
 2193
 0.24
chr21_17457844_17457995 0.16 ENSG00000252273
 .
 50090
 0.19
chr10_43046062_43046288 0.16 ENSG00000251783
 .
 54431
 0.14
chr13_28929966_28930249 0.16 FLT1
 fms-related tyrosine kinase 1
 9681
 0.28
chr14_24522539_24522690 0.16 LRRC16B
 leucine rich repeat containing 16B
 1405
 0.24
chr19_21646642_21646886 0.16 ZNF429
 zinc finger protein 429
 41602
 0.16
chr10_11268288_11268534 0.16 RP3-323N1.2
55072
 0.13
chr4_108973680_108973847 0.16 HADH
 hydroxyacyl-CoA dehydrogenase
 47972
 0.14
chr2_62448746_62448902 0.16 B3GNT2
 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2
 6171
 0.18

Histogram of CRE-TSS distances for CREs targeted by :

Histogram of

Rank distribution of CRE target scores:

Histogram of target CRE score.

Distribution of target CREs across different genomic regions:

Weighted Piechart of Weighted Piechart of Weighted Piechart of

Network of associatons between targets according to the STRING database.

First level regulatory network of PAX3

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0019276 UDP-N-acetylgalactosamine metabolic process(GO:0019276)
0.1 0.4 GO:0033152 immunoglobulin V(D)J recombination(GO:0033152)
0.1 0.1 GO:0002326 B cell lineage commitment(GO:0002326)
0.1 0.3 GO:1901341 activation of store-operated calcium channel activity(GO:0032237) regulation of store-operated calcium channel activity(GO:1901339) positive regulation of store-operated calcium channel activity(GO:1901341)
0.1 0.3 GO:0010867 positive regulation of triglyceride biosynthetic process(GO:0010867)
0.1 0.3 GO:0001911 negative regulation of leukocyte mediated cytotoxicity(GO:0001911)
0.1 0.3 GO:0030854 positive regulation of granulocyte differentiation(GO:0030854)
0.1 0.1 GO:0002677 negative regulation of chronic inflammatory response(GO:0002677)
0.1 0.1 GO:0072600 protein targeting to Golgi(GO:0000042) establishment of protein localization to Golgi(GO:0072600)
0.0 0.2 GO:0045589 regulation of regulatory T cell differentiation(GO:0045589)
0.0 0.0 GO:0010572 positive regulation of platelet activation(GO:0010572)
0.0 0.0 GO:0050862 positive regulation of T cell receptor signaling pathway(GO:0050862)
0.0 0.2 GO:0030644 cellular chloride ion homeostasis(GO:0030644) chloride ion homeostasis(GO:0055064)
0.0 0.3 GO:0030206 chondroitin sulfate biosynthetic process(GO:0030206)
0.0 0.2 GO:0070670 response to interleukin-4(GO:0070670)
0.0 0.1 GO:0045722 positive regulation of gluconeogenesis(GO:0045722)
0.0 0.3 GO:0007172 signal complex assembly(GO:0007172)
0.0 0.1 GO:0018125 peptidyl-cysteine methylation(GO:0018125)
0.0 0.2 GO:0002313 mature B cell differentiation involved in immune response(GO:0002313)
0.0 0.1 GO:0046642 negative regulation of alpha-beta T cell proliferation(GO:0046642)
0.0 0.1 GO:0031936 negative regulation of chromatin silencing(GO:0031936)
0.0 0.1 GO:0017183 peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183)
0.0 0.1 GO:0031946 regulation of glucocorticoid biosynthetic process(GO:0031946)
0.0 1.0 GO:0050690 regulation of defense response to virus by virus(GO:0050690)
0.0 0.0 GO:0035234 ectopic germ cell programmed cell death(GO:0035234)
0.0 0.1 GO:0010447 response to acidic pH(GO:0010447)
0.0 0.1 GO:0060426 lung vasculature development(GO:0060426)
0.0 0.1 GO:0070672 response to interleukin-15(GO:0070672)
0.0 0.1 GO:0033622 integrin activation(GO:0033622)
0.0 0.4 GO:0032733 positive regulation of interleukin-10 production(GO:0032733)
0.0 0.4 GO:0030260 entry into host cell(GO:0030260) entry into host(GO:0044409) entry into cell of other organism involved in symbiotic interaction(GO:0051806) entry into other organism involved in symbiotic interaction(GO:0051828)
0.0 0.2 GO:0006198 cAMP catabolic process(GO:0006198)
0.0 0.0 GO:0002666 T cell tolerance induction(GO:0002517) regulation of T cell tolerance induction(GO:0002664) positive regulation of T cell tolerance induction(GO:0002666)
0.0 0.1 GO:0030812 negative regulation of nucleotide catabolic process(GO:0030812)
0.0 0.1 GO:0052169 pathogen-associated molecular pattern dependent induction by symbiont of host innate immune response(GO:0052033) positive regulation by symbiont of host innate immune response(GO:0052166) modulation by symbiont of host innate immune response(GO:0052167) pathogen-associated molecular pattern dependent modulation by symbiont of host innate immune response(GO:0052169) pathogen-associated molecular pattern dependent induction by organism of innate immune response of other organism involved in symbiotic interaction(GO:0052257) positive regulation by organism of innate immune response in other organism involved in symbiotic interaction(GO:0052305) modulation by organism of innate immune response in other organism involved in symbiotic interaction(GO:0052306) pathogen-associated molecular pattern dependent modulation by organism of innate immune response in other organism involved in symbiotic interaction(GO:0052308)
0.0 0.1 GO:0002323 natural killer cell activation involved in immune response(GO:0002323) natural killer cell degranulation(GO:0043320)
0.0 0.1 GO:0072216 positive regulation of metanephros development(GO:0072216)
0.0 0.1 GO:0060242 contact inhibition(GO:0060242)
0.0 0.0 GO:0002643 regulation of tolerance induction(GO:0002643) positive regulation of tolerance induction(GO:0002645)
0.0 0.1 GO:0010956 negative regulation of calcidiol 1-monooxygenase activity(GO:0010956) negative regulation of vitamin D biosynthetic process(GO:0010957) negative regulation of vitamin metabolic process(GO:0046137)
0.0 0.1 GO:0051459 corticotropin secretion(GO:0051458) regulation of corticotropin secretion(GO:0051459) positive regulation of corticotropin secretion(GO:0051461)
0.0 0.1 GO:0046958 nonassociative learning(GO:0046958)
0.0 0.1 GO:0002507 tolerance induction(GO:0002507)
0.0 0.1 GO:0006855 drug transmembrane transport(GO:0006855)
0.0 0.1 GO:0045341 MHC class I biosynthetic process(GO:0045341) regulation of MHC class I biosynthetic process(GO:0045343)
0.0 0.0 GO:0033173 calcineurin-NFAT signaling cascade(GO:0033173)
0.0 0.1 GO:0051533 positive regulation of NFAT protein import into nucleus(GO:0051533)
0.0 0.1 GO:0006772 thiamine metabolic process(GO:0006772)
0.0 0.1 GO:0070498 interleukin-1-mediated signaling pathway(GO:0070498)
0.0 0.0 GO:0048541 Peyer's patch development(GO:0048541)
0.0 0.0 GO:0001661 conditioned taste aversion(GO:0001661)
0.0 0.0 GO:0030223 neutrophil differentiation(GO:0030223)
0.0 0.1 GO:0010452 histone H3-K36 methylation(GO:0010452)
0.0 0.1 GO:0007100 mitotic centrosome separation(GO:0007100)
0.0 0.0 GO:0033091 positive regulation of immature T cell proliferation(GO:0033091)
0.0 0.1 GO:0022614 membrane to membrane docking(GO:0022614)
0.0 0.1 GO:0060218 hematopoietic stem cell differentiation(GO:0060218)
0.0 0.0 GO:0032703 negative regulation of interleukin-2 production(GO:0032703)
0.0 0.1 GO:1901797 negative regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043518) negative regulation of signal transduction by p53 class mediator(GO:1901797)
0.0 0.1 GO:0071481 cellular response to X-ray(GO:0071481)
0.0 0.1 GO:0034219 carbohydrate transmembrane transport(GO:0034219)
0.0 0.5 GO:0045576 mast cell activation(GO:0045576)
0.0 0.0 GO:0043300 regulation of leukocyte degranulation(GO:0043300)
0.0 0.2 GO:0043550 regulation of lipid kinase activity(GO:0043550)
0.0 0.1 GO:0031641 regulation of myelination(GO:0031641)
0.0 0.1 GO:0032927 positive regulation of activin receptor signaling pathway(GO:0032927)
0.0 0.0 GO:0046101 hypoxanthine biosynthetic process(GO:0046101)
0.0 0.1 GO:0002634 regulation of germinal center formation(GO:0002634)
0.0 0.2 GO:0040023 establishment of nucleus localization(GO:0040023)
0.0 0.1 GO:0033169 histone H3-K9 demethylation(GO:0033169)
0.0 0.2 GO:0008653 lipopolysaccharide metabolic process(GO:0008653)
0.0 0.1 GO:0034314 Arp2/3 complex-mediated actin nucleation(GO:0034314)
0.0 0.1 GO:0015904 tetracycline transport(GO:0015904)
0.0 0.2 GO:0043368 positive T cell selection(GO:0043368)
0.0 0.1 GO:0015886 heme transport(GO:0015886)
0.0 0.1 GO:0001672 regulation of chromatin assembly or disassembly(GO:0001672)
0.0 0.1 GO:0070172 positive regulation of tooth mineralization(GO:0070172)
0.0 0.1 GO:0060437 lung growth(GO:0060437)
0.0 0.1 GO:0048261 negative regulation of receptor-mediated endocytosis(GO:0048261)
0.0 0.1 GO:0010159 specification of organ position(GO:0010159)
0.0 0.0 GO:0033632 regulation of cell-cell adhesion mediated by integrin(GO:0033632)
0.0 0.1 GO:0010759 positive regulation of macrophage chemotaxis(GO:0010759)
0.0 0.3 GO:0046579 positive regulation of Ras protein signal transduction(GO:0046579)
0.0 0.1 GO:0042989 sequestering of actin monomers(GO:0042989)
0.0 0.1 GO:0006032 chitin metabolic process(GO:0006030) chitin catabolic process(GO:0006032)
0.0 0.0 GO:0072217 negative regulation of metanephros development(GO:0072217)
0.0 0.1 GO:0000183 chromatin silencing at rDNA(GO:0000183)
0.0 0.1 GO:0060123 regulation of growth hormone secretion(GO:0060123)
0.0 0.1 GO:0010815 bradykinin catabolic process(GO:0010815)
0.0 0.0 GO:0002282 microglial cell activation involved in immune response(GO:0002282)
0.0 0.1 GO:0019228 neuronal action potential(GO:0019228)
0.0 0.1 GO:0050858 negative regulation of antigen receptor-mediated signaling pathway(GO:0050858) negative regulation of T cell receptor signaling pathway(GO:0050860)
0.0 0.1 GO:0019934 cGMP-mediated signaling(GO:0019934)
0.0 0.2 GO:0043388 positive regulation of DNA binding(GO:0043388)
0.0 0.0 GO:0010592 positive regulation of lamellipodium assembly(GO:0010592) positive regulation of lamellipodium organization(GO:1902745)
0.0 0.0 GO:0036336 dendritic cell chemotaxis(GO:0002407) dendritic cell migration(GO:0036336)
0.0 0.6 GO:0034111 negative regulation of homotypic cell-cell adhesion(GO:0034111)
0.0 0.1 GO:0090224 regulation of spindle organization(GO:0090224)
0.0 0.0 GO:0052564 response to immune response of other organism involved in symbiotic interaction(GO:0052564) response to host immune response(GO:0052572)
0.0 0.2 GO:0031146 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process(GO:0031146)
0.0 0.0 GO:0071379 cellular response to prostaglandin stimulus(GO:0071379)
0.0 0.1 GO:0051770 positive regulation of nitric-oxide synthase biosynthetic process(GO:0051770)
0.0 0.1 GO:0033603 positive regulation of dopamine secretion(GO:0033603)
0.0 0.1 GO:0070682 proteasome regulatory particle assembly(GO:0070682)
0.0 0.0 GO:0032613 interleukin-10 production(GO:0032613)
0.0 0.1 GO:0045084 positive regulation of interleukin-12 biosynthetic process(GO:0045084)
0.0 0.0 GO:0097300 necroptotic process(GO:0070266) programmed necrotic cell death(GO:0097300)
0.0 0.1 GO:0043653 mitochondrial fragmentation involved in apoptotic process(GO:0043653)
0.0 0.1 GO:0050961 detection of temperature stimulus involved in sensory perception(GO:0050961) detection of temperature stimulus involved in sensory perception of pain(GO:0050965)
0.0 0.1 GO:0046477 glycosylceramide catabolic process(GO:0046477)
0.0 0.5 GO:1901185 negative regulation of epidermal growth factor receptor signaling pathway(GO:0042059) negative regulation of ERBB signaling pathway(GO:1901185)
0.0 0.2 GO:0000381 regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.0 0.1 GO:0003215 cardiac right ventricle morphogenesis(GO:0003215)
0.0 0.1 GO:0050672 negative regulation of mononuclear cell proliferation(GO:0032945) negative regulation of lymphocyte proliferation(GO:0050672)
0.0 0.1 GO:0033522 histone H2A ubiquitination(GO:0033522)
0.0 0.2 GO:0042273 ribosomal large subunit biogenesis(GO:0042273)
0.0 0.1 GO:0042535 positive regulation of tumor necrosis factor biosynthetic process(GO:0042535)
0.0 0.0 GO:0032506 cytokinetic process(GO:0032506)
0.0 0.0 GO:0006925 inflammatory cell apoptotic process(GO:0006925)
0.0 0.0 GO:0009313 oligosaccharide catabolic process(GO:0009313)
0.0 0.0 GO:0035581 sequestering of extracellular ligand from receptor(GO:0035581) sequestering of TGFbeta in extracellular matrix(GO:0035583) protein localization to extracellular region(GO:0071692) maintenance of protein location in extracellular region(GO:0071694) extracellular regulation of signal transduction(GO:1900115) extracellular negative regulation of signal transduction(GO:1900116)
0.0 0.0 GO:0051103 DNA ligation involved in DNA repair(GO:0051103)
0.0 0.1 GO:0050957 equilibrioception(GO:0050957)
0.0 0.1 GO:0006570 tyrosine metabolic process(GO:0006570)
0.0 0.1 GO:0008354 germ cell migration(GO:0008354)
0.0 0.1 GO:0008298 intracellular mRNA localization(GO:0008298)
0.0 0.1 GO:0043353 enucleate erythrocyte differentiation(GO:0043353)
0.0 0.1 GO:0052805 histidine catabolic process(GO:0006548) imidazole-containing compound catabolic process(GO:0052805)
0.0 0.1 GO:0006122 mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122)
0.0 0.0 GO:0016242 negative regulation of macroautophagy(GO:0016242)
0.0 0.0 GO:0009189 deoxyribonucleoside diphosphate biosynthetic process(GO:0009189)
0.0 0.1 GO:0006895 Golgi to endosome transport(GO:0006895) Golgi to vacuole transport(GO:0006896)
0.0 0.1 GO:0061756 leukocyte tethering or rolling(GO:0050901) leukocyte adhesion to vascular endothelial cell(GO:0061756)
0.0 0.1 GO:0008588 release of cytoplasmic sequestered NF-kappaB(GO:0008588)
0.0 0.0 GO:0015816 glycine transport(GO:0015816)
0.0 0.0 GO:0002888 regulation of myeloid leukocyte mediated immunity(GO:0002886) positive regulation of myeloid leukocyte mediated immunity(GO:0002888)
0.0 0.0 GO:2000831 corticosteroid hormone secretion(GO:0035930) regulation of steroid hormone secretion(GO:2000831) regulation of corticosteroid hormone secretion(GO:2000846)
0.0 0.1 GO:0007195 adenylate cyclase-inhibiting dopamine receptor signaling pathway(GO:0007195)
0.0 0.0 GO:0034063 stress granule assembly(GO:0034063)
0.0 0.1 GO:0034755 iron ion transmembrane transport(GO:0034755)
0.0 0.0 GO:0010980 regulation of vitamin D 24-hydroxylase activity(GO:0010979) positive regulation of vitamin D 24-hydroxylase activity(GO:0010980)
0.0 0.0 GO:0021778 spinal cord oligodendrocyte cell differentiation(GO:0021529) spinal cord oligodendrocyte cell fate specification(GO:0021530) oligodendrocyte cell fate specification(GO:0021778) glial cell fate specification(GO:0021780)
0.0 0.0 GO:0042339 keratan sulfate metabolic process(GO:0042339)
0.0 0.1 GO:0050908 detection of light stimulus involved in visual perception(GO:0050908) detection of light stimulus involved in sensory perception(GO:0050962)
0.0 0.1 GO:0030490 maturation of SSU-rRNA(GO:0030490)
0.0 0.0 GO:0042996 regulation of Golgi to plasma membrane protein transport(GO:0042996)
0.0 0.1 GO:0007007 inner mitochondrial membrane organization(GO:0007007)
0.0 0.0 GO:1901072 amino sugar catabolic process(GO:0046348) glucosamine-containing compound catabolic process(GO:1901072)
0.0 0.1 GO:0000380 alternative mRNA splicing, via spliceosome(GO:0000380)
0.0 0.1 GO:0033119 negative regulation of RNA splicing(GO:0033119)
0.0 0.1 GO:0000098 sulfur amino acid catabolic process(GO:0000098)
0.0 0.1 GO:0006477 protein sulfation(GO:0006477)
0.0 0.0 GO:0051057 positive regulation of small GTPase mediated signal transduction(GO:0051057)
0.0 0.1 GO:0045078 positive regulation of interferon-gamma biosynthetic process(GO:0045078)
0.0 0.1 GO:0006432 phenylalanyl-tRNA aminoacylation(GO:0006432)
0.0 0.0 GO:0045075 interleukin-12 biosynthetic process(GO:0042090) regulation of interleukin-12 biosynthetic process(GO:0045075)
0.0 0.1 GO:0006003 fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.0 0.0 GO:0009106 lipoate metabolic process(GO:0009106)
0.0 0.0 GO:0007221 positive regulation of transcription of Notch receptor target(GO:0007221)
0.0 0.1 GO:0009414 response to water deprivation(GO:0009414) response to water(GO:0009415)
0.0 0.1 GO:0045061 thymic T cell selection(GO:0045061)
0.0 0.1 GO:0070570 regulation of axon regeneration(GO:0048679) regulation of neuron projection regeneration(GO:0070570)
0.0 0.1 GO:1901976 regulation of cell cycle checkpoint(GO:1901976)
0.0 0.0 GO:0018119 protein nitrosylation(GO:0017014) peptidyl-cysteine S-nitrosylation(GO:0018119)
0.0 0.0 GO:0046502 uroporphyrinogen III metabolic process(GO:0046502)
0.0 0.1 GO:0006491 N-glycan processing(GO:0006491)
0.0 0.0 GO:0006104 succinyl-CoA metabolic process(GO:0006104)
0.0 0.0 GO:0061640 cytoskeleton-dependent cytokinesis(GO:0061640)
0.0 0.0 GO:0034625 fatty acid elongation, monounsaturated fatty acid(GO:0034625)
0.0 0.2 GO:0050832 defense response to fungus(GO:0050832)
0.0 0.1 GO:0034643 establishment of mitochondrion localization, microtubule-mediated(GO:0034643) mitochondrion transport along microtubule(GO:0047497)
0.0 0.1 GO:0006545 glycine biosynthetic process(GO:0006545)
0.0 0.0 GO:0051299 centrosome separation(GO:0051299)
0.0 0.1 GO:0000303 response to superoxide(GO:0000303)
0.0 0.0 GO:0002031 G-protein coupled receptor internalization(GO:0002031)
0.0 0.0 GO:0045657 positive regulation of monocyte differentiation(GO:0045657)
0.0 0.0 GO:0045603 positive regulation of endothelial cell differentiation(GO:0045603)
0.0 0.0 GO:0021830 interneuron migration from the subpallium to the cortex(GO:0021830) cerebral cortex GABAergic interneuron migration(GO:0021853) cerebral cortex GABAergic interneuron development(GO:0021894) interneuron migration(GO:1904936)
0.0 0.1 GO:0007130 synaptonemal complex assembly(GO:0007130)
0.0 0.1 GO:0033158 regulation of protein import into nucleus, translocation(GO:0033158)
0.0 0.0 GO:0032627 interleukin-23 production(GO:0032627) regulation of interleukin-23 production(GO:0032667) positive regulation of interleukin-23 production(GO:0032747)
0.0 0.0 GO:0045672 positive regulation of osteoclast differentiation(GO:0045672)
0.0 0.0 GO:0042510 regulation of tyrosine phosphorylation of Stat1 protein(GO:0042510)
0.0 0.0 GO:0008054 negative regulation of cyclin-dependent protein serine/threonine kinase by cyclin degradation(GO:0008054)
0.0 0.1 GO:0002483 antigen processing and presentation of endogenous peptide antigen(GO:0002483) antigen processing and presentation of endogenous peptide antigen via MHC class I(GO:0019885)
0.0 0.0 GO:0008628 hormone-mediated apoptotic signaling pathway(GO:0008628)
0.0 0.1 GO:0006685 sphingomyelin catabolic process(GO:0006685)
0.0 0.0 GO:0035610 C-terminal protein deglutamylation(GO:0035609) protein side chain deglutamylation(GO:0035610)
0.0 0.0 GO:0034720 histone H3-K4 demethylation(GO:0034720)
0.0 0.0 GO:0034122 negative regulation of toll-like receptor signaling pathway(GO:0034122)
0.0 0.1 GO:0071168 protein localization to chromatin(GO:0071168)
0.0 0.0 GO:0002238 response to molecule of fungal origin(GO:0002238)
0.0 0.1 GO:0051923 sulfation(GO:0051923)
0.0 0.1 GO:0090114 vesicle targeting, rough ER to cis-Golgi(GO:0048207) COPII vesicle coating(GO:0048208) COPII-coated vesicle budding(GO:0090114)
0.0 0.0 GO:0006667 sphinganine metabolic process(GO:0006667)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)
0.0 0.3 GO:0001891 phagocytic cup(GO:0001891)
0.0 0.3 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.0 0.2 GO:0045240 dihydrolipoyl dehydrogenase complex(GO:0045240)
0.0 0.1 GO:0032591 dendritic spine membrane(GO:0032591)
0.0 0.1 GO:0032009 early phagosome(GO:0032009)
0.0 0.1 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.0 0.1 GO:0033553 rDNA heterochromatin(GO:0033553)
0.0 0.3 GO:0071203 WASH complex(GO:0071203)
0.0 0.8 GO:0030175 filopodium(GO:0030175)
0.0 0.1 GO:0072669 tRNA-splicing ligase complex(GO:0072669)
0.0 0.1 GO:0031088 platelet dense granule membrane(GO:0031088)
0.0 0.1 GO:0005672 transcription factor TFIIA complex(GO:0005672)
0.0 0.1 GO:0005954 calcium- and calmodulin-dependent protein kinase complex(GO:0005954)
0.0 0.1 GO:0042629 mast cell granule(GO:0042629)
0.0 0.1 GO:0008540 proteasome regulatory particle, base subcomplex(GO:0008540)
0.0 0.1 GO:0048179 activin receptor complex(GO:0048179)
0.0 0.1 GO:0045323 interleukin-1 receptor complex(GO:0045323)
0.0 0.1 GO:0000300 obsolete peripheral to membrane of membrane fraction(GO:0000300)
0.0 0.0 GO:0070022 transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.0 0.1 GO:0070695 FHF complex(GO:0070695)
0.0 0.1 GO:0000137 Golgi cis cisterna(GO:0000137)
0.0 0.1 GO:0005638 lamin filament(GO:0005638)
0.0 0.1 GO:0070776 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.0 0.0 GO:0030062 mitochondrial tricarboxylic acid cycle enzyme complex(GO:0030062)
0.0 0.0 GO:0071438 invadopodium membrane(GO:0071438)
0.0 0.1 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
0.0 0.1 GO:0033162 melanosome membrane(GO:0033162) chitosome(GO:0045009)
0.0 0.0 GO:0071437 invadopodium(GO:0071437)
0.0 0.0 GO:0000942 condensed nuclear chromosome outer kinetochore(GO:0000942)
0.0 0.0 GO:1990316 ATG1/ULK1 kinase complex(GO:1990316)
0.0 0.2 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.0 0.1 GO:0030127 COPII vesicle coat(GO:0030127)
0.0 0.0 GO:0005686 U2 snRNP(GO:0005686)
0.0 0.1 GO:0005838 proteasome regulatory particle(GO:0005838)
0.0 0.2 GO:0030914 STAGA complex(GO:0030914)
0.0 0.1 GO:0000421 autophagosome membrane(GO:0000421)
0.0 0.2 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.0 0.0 GO:0000407 pre-autophagosomal structure(GO:0000407) pre-autophagosomal structure membrane(GO:0034045)
0.0 0.0 GO:0031371 ubiquitin conjugating enzyme complex(GO:0031371)
0.0 0.1 GO:0000153 cytoplasmic ubiquitin ligase complex(GO:0000153)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0047238 glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity(GO:0047238)
0.1 0.4 GO:0016494 C-X-C chemokine receptor activity(GO:0016494)
0.1 0.2 GO:0016309 1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
0.1 0.4 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.1 0.2 GO:0047756 chondroitin 4-sulfotransferase activity(GO:0047756)
0.0 0.2 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454)
0.0 0.1 GO:0004167 dopachrome isomerase activity(GO:0004167)
0.0 0.1 GO:0016842 amidine-lyase activity(GO:0016842)
0.0 0.1 GO:0004465 lipoprotein lipase activity(GO:0004465)
0.0 0.2 GO:0046934 phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) phosphatidylinositol bisphosphate kinase activity(GO:0052813)
0.0 0.2 GO:0042043 neurexin family protein binding(GO:0042043)
0.0 0.1 GO:0017159 pantetheine hydrolase activity(GO:0017159)
0.0 0.1 GO:0033691 sialic acid binding(GO:0033691)
0.0 0.1 GO:0015562 efflux transmembrane transporter activity(GO:0015562)
0.0 0.1 GO:0032296 ribonuclease III activity(GO:0004525) double-stranded RNA-specific ribonuclease activity(GO:0032296)
0.0 0.2 GO:0046790 virion binding(GO:0046790)
0.0 0.1 GO:0052658 inositol-1,4,5-trisphosphate 5-phosphatase activity(GO:0052658) inositol-1,3,4,5-tetrakisphosphate 5-phosphatase activity(GO:0052659)
0.0 0.4 GO:0004950 G-protein coupled chemoattractant receptor activity(GO:0001637) chemokine receptor activity(GO:0004950)
0.0 0.1 GO:0034236 protein kinase A catalytic subunit binding(GO:0034236)
0.0 0.1 GO:0019834 phospholipase A2 inhibitor activity(GO:0019834)
0.0 0.1 GO:0035197 siRNA binding(GO:0035197)
0.0 0.0 GO:0016312 inositol bisphosphate phosphatase activity(GO:0016312)
0.0 0.1 GO:0003987 acetate-CoA ligase activity(GO:0003987)
0.0 0.1 GO:0004969 histamine receptor activity(GO:0004969)
0.0 0.1 GO:0015520 tetracycline:proton antiporter activity(GO:0015520)
0.0 0.1 GO:0047894 flavonol 3-sulfotransferase activity(GO:0047894)
0.0 0.1 GO:0004911 interleukin-2 receptor activity(GO:0004911)
0.0 0.1 GO:0008545 JUN kinase kinase activity(GO:0008545)
0.0 0.5 GO:0045028 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.0 0.9 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.0 0.1 GO:0034237 protein kinase A regulatory subunit binding(GO:0034237)
0.0 0.1 GO:0015232 heme transporter activity(GO:0015232)
0.0 0.1 GO:0019215 intermediate filament binding(GO:0019215)
0.0 0.1 GO:0042799 histone methyltransferase activity (H4-K20 specific)(GO:0042799)
0.0 0.1 GO:0004064 arylesterase activity(GO:0004064)
0.0 0.1 GO:0004568 chitinase activity(GO:0004568)
0.0 0.2 GO:0019864 IgG binding(GO:0019864)
0.0 0.1 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.0 0.1 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
0.0 0.1 GO:0030375 thyroid hormone receptor coactivator activity(GO:0030375)
0.0 0.1 GO:0015925 galactosidase activity(GO:0015925)
0.0 0.1 GO:0005220 inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.0 0.1 GO:0042156 obsolete zinc-mediated transcriptional activator activity(GO:0042156)
0.0 0.1 GO:0030955 potassium ion binding(GO:0030955)
0.0 0.1 GO:0004591 oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591)
0.0 0.1 GO:0004677 DNA-dependent protein kinase activity(GO:0004677)
0.0 0.1 GO:0046974 histone methyltransferase activity (H3-K9 specific)(GO:0046974)
0.0 0.2 GO:0004467 long-chain fatty acid-CoA ligase activity(GO:0004467)
0.0 0.0 GO:0042577 lipid phosphatase activity(GO:0042577)
0.0 0.1 GO:0005381 iron ion transmembrane transporter activity(GO:0005381)
0.0 0.1 GO:0004904 interferon receptor activity(GO:0004904)
0.0 0.1 GO:0001595 angiotensin receptor activity(GO:0001595) angiotensin type II receptor activity(GO:0004945)
0.0 0.0 GO:0043559 insulin binding(GO:0043559)
0.0 0.1 GO:0005092 GDP-dissociation inhibitor activity(GO:0005092)
0.0 0.2 GO:0005031 tumor necrosis factor-activated receptor activity(GO:0005031)
0.0 0.0 GO:0034481 chondroitin sulfotransferase activity(GO:0034481)
0.0 0.0 GO:0016748 succinyltransferase activity(GO:0016748)
0.0 0.0 GO:0004774 succinate-CoA ligase activity(GO:0004774)
0.0 0.1 GO:0070097 delta-catenin binding(GO:0070097)
0.0 0.1 GO:0050700 CARD domain binding(GO:0050700)
0.0 0.0 GO:0004514 nicotinate-nucleotide diphosphorylase (carboxylating) activity(GO:0004514)
0.0 0.3 GO:0042169 SH2 domain binding(GO:0042169)
0.0 0.1 GO:0070053 thrombospondin receptor activity(GO:0070053)
0.0 0.0 GO:0004556 alpha-amylase activity(GO:0004556) amylase activity(GO:0016160)
0.0 0.2 GO:0005095 GTPase inhibitor activity(GO:0005095)
0.0 0.1 GO:0016670 oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor(GO:0016670)
0.0 0.1 GO:0050733 RS domain binding(GO:0050733)
0.0 0.2 GO:0031593 polyubiquitin binding(GO:0031593)
0.0 0.1 GO:0004908 interleukin-1 receptor activity(GO:0004908)
0.0 0.1 GO:0042285 UDP-xylosyltransferase activity(GO:0035252) xylosyltransferase activity(GO:0042285)
0.0 0.1 GO:0004955 prostaglandin receptor activity(GO:0004955)
0.0 0.1 GO:0016624 oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor(GO:0016624)
0.0 0.0 GO:0004946 bombesin receptor activity(GO:0004946)
0.0 0.1 GO:0004704 NF-kappaB-inducing kinase activity(GO:0004704)
0.0 0.1 GO:0004826 phenylalanine-tRNA ligase activity(GO:0004826)
0.0 0.1 GO:0003873 6-phosphofructo-2-kinase activity(GO:0003873)
0.0 0.1 GO:0070513 death domain binding(GO:0070513)
0.0 0.1 GO:0030284 estrogen receptor activity(GO:0030284)
0.0 0.1 GO:0070087 chromo shadow domain binding(GO:0070087)
0.0 0.2 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.0 0.0 GO:0004967 glucagon receptor activity(GO:0004967)
0.0 0.1 GO:0004952 dopamine neurotransmitter receptor activity(GO:0004952)
0.0 0.1 GO:0016833 oxo-acid-lyase activity(GO:0016833)
0.0 0.1 GO:0060228 phosphatidylcholine-sterol O-acyltransferase activator activity(GO:0060228)
0.0 0.0 GO:0070644 vitamin D response element binding(GO:0070644)
0.0 0.1 GO:0003688 DNA replication origin binding(GO:0003688)
0.0 0.1 GO:0008175 tRNA methyltransferase activity(GO:0008175)
0.0 0.0 GO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.0 0.0 GO:0034711 inhibin binding(GO:0034711)
0.0 0.0 GO:0015037 peptide disulfide oxidoreductase activity(GO:0015037)
0.0 0.0 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.0 0.0 GO:0004340 glucokinase activity(GO:0004340)
0.0 0.1 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.0 0.1 GO:0008526 phosphatidylinositol transporter activity(GO:0008526)
0.0 0.1 GO:0001784 phosphotyrosine binding(GO:0001784)
0.0 0.0 GO:0032453 histone demethylase activity (H3-K4 specific)(GO:0032453) histone demethylase activity (H3-dimethyl-K4 specific)(GO:0034648)
0.0 0.0 GO:0002060 purine nucleobase binding(GO:0002060)
0.0 0.1 GO:0030275 LRR domain binding(GO:0030275)
0.0 0.1 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.0 0.0 GO:0003953 NAD+ nucleosidase activity(GO:0003953)
0.0 0.1 GO:0032407 MutSalpha complex binding(GO:0032407)
0.0 0.0 GO:0008493 tetracycline transporter activity(GO:0008493)
0.0 0.0 GO:0042978 ornithine decarboxylase activator activity(GO:0042978)
0.0 0.0 GO:0005536 glucose binding(GO:0005536)
0.0 0.2 GO:0004364 glutathione transferase activity(GO:0004364)
0.0 0.1 GO:0019992 diacylglycerol binding(GO:0019992)
0.0 0.1 GO:0008079 translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079)
0.0 0.0 GO:0019870 potassium channel inhibitor activity(GO:0019870)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.0 PID EPHRINB REV PATHWAY Ephrin B reverse signaling
0.0 0.5 PID TCR JNK PATHWAY JNK signaling in the CD4+ TCR pathway
0.0 0.3 ST TYPE I INTERFERON PATHWAY Type I Interferon (alpha/beta IFN) Pathway
0.0 0.4 SA PTEN PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.0 0.8 PID ERBB1 INTERNALIZATION PATHWAY Internalization of ErbB1
0.0 0.6 PID IL8 CXCR2 PATHWAY IL8- and CXCR2-mediated signaling events
0.0 0.9 PID TCR PATHWAY TCR signaling in naïve CD4+ T cells
0.0 0.7 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0 0.1 SA FAS SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.0 0.4 PID IL1 PATHWAY IL1-mediated signaling events
0.0 0.2 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0 0.4 PID IL6 7 PATHWAY IL6-mediated signaling events
0.0 0.4 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.0 0.1 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.0 0.0 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.0 0.0 ST INTERFERON GAMMA PATHWAY Interferon gamma pathway.
0.0 0.0 PID IGF1 PATHWAY IGF1 pathway
0.0 0.2 PID BCR 5PATHWAY BCR signaling pathway
0.0 0.1 PID NFKAPPAB CANONICAL PATHWAY Canonical NF-kappaB pathway
0.0 0.1 PID ER NONGENOMIC PATHWAY Plasma membrane estrogen receptor signaling
0.0 0.0 PID CXCR3 PATHWAY CXCR3-mediated signaling events
0.0 0.1 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.0 0.2 PID FCER1 PATHWAY Fc-epsilon receptor I signaling in mast cells
0.0 0.1 PID FAS PATHWAY FAS (CD95) signaling pathway
0.0 0.0 PID TCR RAS PATHWAY Ras signaling in the CD4+ TCR pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 REACTOME BINDING AND ENTRY OF HIV VIRION Genes involved in Binding and entry of HIV virion
0.1 0.6 REACTOME CD28 DEPENDENT VAV1 PATHWAY Genes involved in CD28 dependent Vav1 pathway
0.0 0.0 REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE Genes involved in Translocation of ZAP-70 to Immunological synapse
0.0 0.0 REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Glutamate Neurotransmitter Release Cycle
0.0 0.4 REACTOME GENERATION OF SECOND MESSENGER MOLECULES Genes involved in Generation of second messenger molecules
0.0 0.4 REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.0 0.8 REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.0 0.1 REACTOME TRAF6 MEDIATED NFKB ACTIVATION Genes involved in TRAF6 mediated NF-kB activation
0.0 0.5 REACTOME GPVI MEDIATED ACTIVATION CASCADE Genes involved in GPVI-mediated activation cascade
0.0 0.2 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
0.0 0.0 REACTOME TRAF3 DEPENDENT IRF ACTIVATION PATHWAY Genes involved in TRAF3-dependent IRF activation pathway
0.0 0.2 REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX UPON TLR7 8 OR 9 STIMULATION Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
0.0 0.4 REACTOME THE ROLE OF NEF IN HIV1 REPLICATION AND DISEASE PATHOGENESIS Genes involved in The role of Nef in HIV-1 replication and disease pathogenesis
0.0 0.2 REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.0 0.2 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.0 0.4 REACTOME CHONDROITIN SULFATE BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
0.0 0.1 REACTOME CTLA4 INHIBITORY SIGNALING Genes involved in CTLA4 inhibitory signaling
0.0 0.2 REACTOME ASSOCIATION OF LICENSING FACTORS WITH THE PRE REPLICATIVE COMPLEX Genes involved in Association of licensing factors with the pre-replicative complex
0.0 0.3 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.0 0.1 REACTOME PROSTANOID LIGAND RECEPTORS Genes involved in Prostanoid ligand receptors
0.0 0.2 REACTOME PROLACTIN RECEPTOR SIGNALING Genes involved in Prolactin receptor signaling
0.0 0.3 REACTOME IL 2 SIGNALING Genes involved in Interleukin-2 signaling
0.0 0.1 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.0 0.1 REACTOME ROLE OF DCC IN REGULATING APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.0 0.1 REACTOME REGULATION OF INSULIN SECRETION BY GLUCAGON LIKE PEPTIDE1 Genes involved in Regulation of Insulin Secretion by Glucagon-like Peptide-1
0.0 0.1 REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Presynaptic nicotinic acetylcholine receptors
0.0 0.2 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.0 0.0 REACTOME ABACAVIR TRANSPORT AND METABOLISM Genes involved in Abacavir transport and metabolism
0.0 0.1 REACTOME SPRY REGULATION OF FGF SIGNALING Genes involved in Spry regulation of FGF signaling
0.0 0.2 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.0 0.0 REACTOME G1 S SPECIFIC TRANSCRIPTION Genes involved in G1/S-Specific Transcription
0.0 0.1 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
0.0 0.1 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.0 0.6 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0 0.2 REACTOME G0 AND EARLY G1 Genes involved in G0 and Early G1
0.0 0.1 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins
0.0 0.2 REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.0 0.4 REACTOME GLYCOSPHINGOLIPID METABOLISM Genes involved in Glycosphingolipid metabolism
0.0 0.1 REACTOME CTNNB1 PHOSPHORYLATION CASCADE Genes involved in Beta-catenin phosphorylation cascade