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ENCODE: H3K4me1 ChIP-Seq of primary human cells

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Results for PAX4

Z-value: 2.19

Motif logo

Transcription factors associated with PAX4

Gene Symbol	Gene ID	Gene Info
PAX4 Ensembl NCBI GeneCards UniProt	ENSG00000106331.10	paired box 4

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE	Gene	Distance	Association probability	Pearson corr. coef.	P-value	Plot
chr7_127260732_127260883	PAX4	4825	0.168732	0.69	4.2e-02	Click!
chr7_127273283_127273434	PAX4	17376	0.137478	-0.68	4.5e-02	Click!
chr7_127272979_127273130	PAX4	17072	0.137930	-0.40	2.8e-01	Click!
chr7_127260343_127260494	PAX4	4436	0.172912	0.22	5.7e-01	Click!
chr7_127269605_127269756	PAX4	13698	0.142839	0.20	6.1e-01	Click!

Activity of the PAX4 motif across conditions

Conditions sorted by the z-value of the PAX4 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE)	Target Score	Top associated gene	Gene Info	Distance of CRE to TSS	CRE/Gene association probability
chr20_48809266_48809488	0.73	CEBPB	CCAAT/enhancer binding protein (C/EBP), beta	2001	0.34
chr9_134147280_134147660	0.65	FAM78A	family with sequence similarity 78, member A	1560	0.37
chr2_10518114_10518365	0.60	HPCAL1	hippocalcin-like 1	41908	0.14
chr12_120445548_120445820	0.57	CCDC64	coiled-coil domain containing 64	18011	0.19
chr3_111854444_111854779	0.56	RP11-757F18.5		2341	0.24
chr13_51466079_51466258	0.54	RNASEH2B-AS1	RNASEH2B antisense RNA 1	390	0.86
chr18_60883221_60883629	0.53	ENSG00000238988	.	21527	0.2
chr8_57123328_57123484	0.51	PLAG1	pleiomorphic adenoma gene 1	432	0.68
chr17_8856804_8857368	0.50	PIK3R5	phosphoinositide-3-kinase, regulatory subunit 5	11938	0.24
chr11_118209098_118209302	0.50	CD3D	CD3d molecule, delta (CD3-TCR complex)	2452	0.18
chrX_153086920_153087071	0.50	PDZD4	PDZ domain containing 4	8356	0.1
chr12_68569539_68569690	0.50	IFNG	interferon, gamma	16087	0.23
chr1_118197732_118198071	0.49	ENSG00000212266	.	33463	0.17
chr16_50303522_50303851	0.47	ADCY7	adenylate cyclase 7	3224	0.27
chr8_37118931_37119082	0.47	RP11-150O12.6		255533	0.02
chr19_42072501_42072652	0.47	CEACAM21	carcinoembryonic antigen-related cell adhesion molecule 21	10011	0.16
chr18_2950520_2950671	0.47	RP11-737O24.2		2256	0.25
chr7_138766008_138766159	0.47	ZC3HAV1	zinc finger CCCH-type, antiviral 1	2070	0.35
chr3_48518423_48518574	0.47	SHISA5	shisa family member 5	3881	0.11
chr17_46458441_46458592	0.47	RP11-433M22.1		784	0.5
chr12_98914776_98914927	0.46	ENSG00000264461	.	3684	0.17
chr2_61694634_61694785	0.46	USP34	ubiquitin specific peptidase 34	3195	0.23
chr15_70821041_70821192	0.46	UACA	uveal autoantigen with coiled-coil domains and ankyrin repeats	173504	0.03
chr20_2721931_2722127	0.46	EBF4	early B-cell factor 4	35142	0.09
chr6_25085634_25085917	0.46	FAM65B	family with sequence similarity 65, member B	43537	0.13
chr20_35271592_35271780	0.46	SLA2	Src-like-adaptor 2	2598	0.2
chr14_102297384_102297535	0.46	CTD-2017C7.1		8409	0.16
chr14_68749171_68749391	0.45	ENSG00000243546	.	46025	0.18
chr1_23928835_23928986	0.45	MDS2	myelodysplastic syndrome 2 translocation associated	24914	0.15
chr2_235280347_235280498	0.45	ARL4C	ADP-ribosylation factor-like 4C	124822	0.06
chr1_223535838_223536089	0.44	SUSD4	sushi domain containing 4	716	0.7
chr6_75914345_75914652	0.44	COL12A1	collagen, type XII, alpha 1	1040	0.6
chr17_46493569_46493720	0.44	SKAP1	src kinase associated phosphoprotein 1	13908	0.14
chr18_13379607_13379896	0.43	LDLRAD4	low density lipoprotein receptor class A domain containing 4	2802	0.23
chr7_157452799_157453022	0.43	AC005481.5	Uncharacterized protein	46195	0.15
chr8_37133739_37133934	0.43	RP11-150O12.6		240703	0.02
chr2_196067620_196067881	0.43	ENSG00000202206	.	311010	0.01
chr1_100905257_100905795	0.42	RP5-837M10.4		46027	0.13
chr18_2635680_2636029	0.42	ENSG00000200875	.	14012	0.13
chr6_130537365_130537658	0.42	SAMD3	sterile alpha motif domain containing 3	432	0.9
chr9_104334199_104334393	0.42	ENSG00000265068	.	22243	0.15
chr15_86235842_86236056	0.42	RP11-815J21.1		8391	0.12
chr22_19567145_19567475	0.42	CLDN5	claudin 5	52242	0.11
chr2_225355399_225355550	0.41	CUL3	cullin 3	7062	0.31
chr12_92796935_92797431	0.41	RP11-693J15.4		18124	0.18
chr2_235348664_235348815	0.41	ARL4C	ADP-ribosylation factor-like 4C	56505	0.17
chr8_22023106_22023363	0.41	BMP1	bone morphogenetic protein 1	434	0.71
chr18_55939835_55940012	0.41	NEDD4L	neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase	50629	0.14
chr21_38458712_38458863	0.41	TTC3	tetratricopeptide repeat domain 3	697	0.62
chr13_41191011_41191162	0.41	FOXO1	forkhead box O1	49648	0.15
chr3_119812472_119812628	0.40	GSK3B	glycogen synthase kinase 3 beta	37	0.98
chr10_32647566_32647717	0.40	RP11-135A24.2		11316	0.13
chr5_39213078_39213229	0.40	FYB	FYN binding protein	6512	0.3
chr2_27615435_27615612	0.40	ZNF513	zinc finger protein 513	11866	0.08
chr10_30992853_30993136	0.40	SVILP1	supervillin pseudogene 1	8144	0.27
chr13_99736374_99736525	0.40	DOCK9	dedicator of cytokinesis 9	2211	0.3
chrX_24204049_24204200	0.40	ZFX	zinc finger protein, X-linked	13292	0.2
chr9_134410289_134410541	0.40	UCK1	uridine-cytidine kinase 1	3760	0.18
chr5_159931051_159931202	0.40	ENSG00000253522	.	18767	0.17
chr22_32521406_32521557	0.40	RP1-127L4.10		4195	0.18
chr10_126849591_126849742	0.40	CTBP2	C-terminal binding protein 2	36	0.99
chr1_151793290_151793755	0.39	RORC	RAR-related orphan receptor C	5045	0.08
chr20_31360169_31360414	0.39	DNMT3B	DNA (cytosine-5-)-methyltransferase 3 beta	7367	0.19
chr6_25086048_25086210	0.39	FAM65B	family with sequence similarity 65, member B	43891	0.13
chr16_85589605_85589868	0.39	GSE1	Gse1 coiled-coil protein	55279	0.13
chr14_91501975_91502157	0.39	RPS6KA5	ribosomal protein S6 kinase, 90kDa, polypeptide 5	24412	0.17
chr1_16489683_16489843	0.39	RP11-276H7.3		4002	0.14
chr15_31282898_31283091	0.39	MTMR10	myotubularin related protein 10	624	0.69
chr6_111521255_111521563	0.39	SLC16A10	solute carrier family 16 (aromatic amino acid transporter), member 10	22994	0.17
chr6_28474532_28474683	0.39	GPX6	glutathione peroxidase 6 (olfactory)	8957	0.17
chr2_105470837_105471020	0.38	POU3F3	POU class 3 homeobox 3	1041	0.29
chr9_92114702_92114853	0.38	SEMA4D	sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D	1732	0.35
chr1_61523146_61523330	0.38	NFIA	nuclear factor I/A	3736	0.28
chr1_67727636_67727815	0.38	ENSG00000252116	.	5684	0.17
chr8_27218022_27218494	0.38	PTK2B	protein tyrosine kinase 2 beta	19910	0.2
chr16_72954955_72955114	0.38	ENSG00000221799	.	63722	0.11
chr9_123668261_123668471	0.38	TRAF1	TNF receptor-associated factor 1	8484	0.2
chr7_17339737_17339909	0.38	AC003075.4		842	0.58
chr5_75766935_75767521	0.38	IQGAP2	IQ motif containing GTPase activating protein 2	66979	0.12
chr1_26699107_26699447	0.38	ZNF683	zinc finger protein 683	11	0.96
chr1_32447200_32447431	0.38	KHDRBS1	KH domain containing, RNA binding, signal transduction associated 1	32115	0.13
chr5_61643922_61644073	0.38	KIF2A	kinesin heavy chain member 2A	13136	0.22
chr14_99730566_99730874	0.38	AL109767.1		1435	0.45
chr12_22317349_22317644	0.38	ENSG00000212172	.	31067	0.22
chr7_23510384_23510575	0.38	IGF2BP3	insulin-like growth factor 2 mRNA binding protein 3	393	0.84
chr9_92091661_92092156	0.37	SEMA4D	sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D	2897	0.31
chr2_171938347_171938679	0.37	TLK1	tousled-like kinase 1	15030	0.25
chr2_131914567_131914718	0.37	PLEKHB2	pleckstrin homology domain containing, family B (evectins) member 2	36127	0.15
chr11_65314789_65315035	0.37	LTBP3	latent transforming growth factor beta binding protein 3	124	0.92
chr1_28583135_28583286	0.37	SESN2	sestrin 2	2828	0.17
chr6_36067796_36067952	0.37	MAPK13	mitogen-activated protein kinase 13	30224	0.14
chr17_38600560_38600819	0.37	IGFBP4	insulin-like growth factor binding protein 4	976	0.46
chr4_48140359_48140728	0.37	TXK	TXK tyrosine kinase	4270	0.19
chr3_98274734_98275185	0.37	GPR15	G protein-coupled receptor 15	24216	0.13
chr7_105333996_105334147	0.37	ATXN7L1	ataxin 7-like 1	1987	0.44
chr17_6937501_6937652	0.37	SLC16A13	solute carrier family 16, member 13	1818	0.14
chr3_60041129_60041280	0.37	NPCDR1	nasopharyngeal carcinoma, down-regulated 1	83621	0.12
chr12_112024853_112025004	0.37	ATXN2	ataxin 2	10683	0.17
chr18_3059069_3059327	0.37	ENSG00000252258	.	33634	0.13
chr7_19155701_19156072	0.36	TWIST1	twist family bHLH transcription factor 1	1409	0.34
chr7_98528228_98528379	0.36	TRRAP	transformation/transcription domain-associated protein	30000	0.15
chr22_40731014_40731199	0.36	ADSL	adenylosuccinate lyase	11401	0.19
chr10_121042857_121043008	0.36	RP11-79M19.2		52762	0.11
chr1_226916264_226916415	0.36	ITPKB	inositol-trisphosphate 3-kinase B	8820	0.23
chr19_18061854_18062005	0.36	KCNN1	potassium intermediate/small conductance calcium-activated channel, subfamily N, member 1	173	0.93
chr2_86106554_86106795	0.36	ST3GAL5	ST3 beta-galactoside alpha-2,3-sialyltransferase 5	7998	0.21
chr22_23180915_23181197	0.36	IGLV3-7	immunoglobulin lambda variable 3-7 (pseudogene)	277	0.69
chrX_49122969_49123120	0.36	FOXP3	forkhead box P3	1756	0.18
chr2_106381793_106382237	0.36	NCK2	NCK adaptor protein 2	19827	0.26
chr13_26476687_26476905	0.36	AL138815.2	Uncharacterized protein	24117	0.17
chr11_128249781_128249932	0.36	ETS1	v-ets avian erythroblastosis virus E26 oncogene homolog 1	125433	0.06
chr11_457057_457213	0.36	RP13-317D12.3		6764	0.09
chr12_90276700_90276872	0.36	ENSG00000252823	.	128950	0.05
chr2_2649601_2649752	0.36	MYT1L	myelin transcription factor 1-like	314710	0.01
chr1_210514835_210515081	0.36	HHAT	hedgehog acyltransferase	12314	0.23
chr17_57230827_57230978	0.36	SKA2	spindle and kinetochore associated complex subunit 2	1633	0.19
chr7_69064525_69064676	0.36	AUTS2	autism susceptibility candidate 2	3	0.99
chr22_42598005_42598156	0.36	TCF20	transcription factor 20 (AR1)	8134	0.18
chr9_132723729_132723880	0.36	RP11-409K20.6		27989	0.16
chr2_183901415_183901683	0.36	NCKAP1	NCK-associated protein 1	1651	0.34
chr18_60799109_60799282	0.35	RP11-299P2.1		19358	0.23
chr15_34901578_34901729	0.35	ENSG00000252425	.	11894	0.17
chr9_131877502_131877715	0.35	PPP2R4	protein phosphatase 2A activator, regulatory subunit 4	3461	0.14
chr1_22405198_22405411	0.35	CDC42-IT1	CDC42 intronic transcript 1 (non-protein coding)	19614	0.13
chr10_119303639_119303790	0.35	EMX2OS	EMX2 opposite strand/antisense RNA	865	0.52
chr8_42040998_42041149	0.35	PLAT	plasminogen activator, tissue	10172	0.15
chr22_39485677_39485862	0.35	RP4-742C19.12		1822	0.25
chr5_50009326_50009477	0.35	PARP8	poly (ADP-ribose) polymerase family, member 8	46010	0.21
chr6_24950484_24950859	0.35	FAM65B	family with sequence similarity 65, member B	14483	0.22
chr3_107695096_107695544	0.35	CD47	CD47 molecule	81888	0.11
chr14_91536496_91536684	0.35	C14orf159	chromosome 14 open reading frame 159	9414	0.17
chr6_150071635_150071860	0.35	PCMT1	protein-L-isoaspartate (D-aspartate) O-methyltransferase	567	0.68
chr20_3794683_3794834	0.35	AP5S1	adaptor-related protein complex 5, sigma 1 subunit	6420	0.13
chr5_68170674_68170825	0.35	ENSG00000212249	.	968	0.69
chr10_71332862_71333013	0.35	NEUROG3	neurogenin 3	57	0.97
chr17_46913678_46913886	0.35	CALCOCO2	calcium binding and coiled-coil domain 2	5143	0.14
chr7_2177726_2177877	0.35	MAD1L1	MAD1 mitotic arrest deficient-like 1 (yeast)	28565	0.21
chr5_35826347_35826592	0.35	CTD-2113L7.1		651	0.73
chr5_88179576_88179735	0.35	MEF2C	myocyte enhancer factor 2C	353	0.55
chr1_183457024_183457378	0.35	SMG7	SMG7 nonsense mediated mRNA decay factor	15134	0.19
chr5_50008539_50008714	0.35	PARP8	poly (ADP-ribose) polymerase family, member 8	45235	0.21
chr18_43265621_43265772	0.35	SLC14A2	solute carrier family 14 (urea transporter), member 2	19589	0.17
chr16_11832325_11832476	0.35	TXNDC11	thioredoxin domain containing 11	2414	0.22
chr12_96792061_96792212	0.35	CDK17	cyclin-dependent kinase 17	1006	0.57
chr16_53530310_53530461	0.35	AKTIP	AKT interacting protein	3856	0.24
chr8_93113767_93114027	0.35	RUNX1T1	runt-related transcription factor 1; translocated to, 1 (cyclin D-related)	1557	0.56
chr1_33429305_33429456	0.35	RNF19B	ring finger protein 19B	906	0.49
chr10_13394172_13394323	0.34	SEPHS1	selenophosphate synthetase 1	3950	0.22
chr17_33894742_33894893	0.34	ENSG00000207297	.	5859	0.11
chr9_77588784_77588935	0.34	RP11-197P3.4		20975	0.15
chr15_86077549_86077700	0.34	AKAP13	A kinase (PRKA) anchor protein 13	9647	0.21
chr7_55538938_55539284	0.34	VOPP1	vesicular, overexpressed in cancer, prosurvival protein 1	44659	0.17
chr14_21945923_21946109	0.34	TOX4	TOX high mobility group box family member 4	633	0.46
chr17_45240872_45241023	0.34	RP5-867C24.4		1517	0.3
chr12_96689153_96689304	0.34	ENSG00000201435	.	8063	0.22
chr6_159228545_159229058	0.34	EZR-AS1	EZR antisense RNA 1	10242	0.17
chr9_100866127_100866462	0.34	TRIM14	tripartite motif containing 14	11451	0.18
chr17_55528272_55528423	0.34	ENSG00000263902	.	38785	0.18
chr12_31960819_31960980	0.34	ENSG00000252204	.	3123	0.21
chr3_100113716_100113867	0.34	LNP1	leukemia NUP98 fusion partner 1	6246	0.2
chr10_25172238_25172596	0.34	ENSG00000240294	.	25324	0.22
chr19_48273702_48273853	0.34	CTD-2571L23.6		1680	0.24
chr10_70092966_70093117	0.34	PBLD	phenazine biosynthesis-like protein domain containing	235	0.88
chr9_107879441_107879592	0.34	ENSG00000201583	.	20479	0.26
chr4_37818298_37818707	0.34	PGM2	phosphoglucomutase 2	9753	0.26
chr2_113954829_113954980	0.34	PSD4	pleckstrin and Sec7 domain containing 4	1047	0.44
chr10_8373199_8373350	0.33	GATA3	GATA binding protein 3	276505	0.02
chr2_162811050_162811201	0.33	ENSG00000253046	.	35833	0.2
chr1_31216034_31216306	0.33	ENSG00000264773	.	4091	0.19
chr5_61603011_61603240	0.33	KIF2A	kinesin heavy chain member 2A	370	0.91
chr19_49891948_49892099	0.33	CCDC155	coiled-coil domain containing 155	386	0.55
chr16_23970694_23970937	0.33	PRKCB	protein kinase C, beta	122271	0.05
chr17_78227050_78227223	0.33	SLC26A11	solute carrier family 26 (anion exchanger), member 11	5123	0.16
chr2_99341231_99341382	0.33	MGAT4A	mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme A	1853	0.41
chr1_150082591_150083110	0.33	PLEKHO1	pleckstrin homology domain containing, family O member 1	38523	0.11
chrX_128911606_128911929	0.33	SASH3	SAM and SH3 domain containing 3	2193	0.32
chr6_112083090_112083534	0.33	FYN	FYN oncogene related to SRC, FGR, YES	2192	0.42
chr6_135408458_135409018	0.33	HBS1L	HBS1-like (S. cerevisiae)	15456	0.2
chr21_46336116_46336464	0.33	ITGB2	integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)	2092	0.18
chr6_112034188_112034365	0.33	FYN	FYN oncogene related to SRC, FGR, YES	6989	0.26
chr1_234536816_234537139	0.33	COA6	cytochrome c oxidase assembly factor 6 homolog (S. cerevisiae)	27530	0.13
chr12_96598172_96598568	0.33	ELK3	ELK3, ETS-domain protein (SRF accessory protein 2)	9978	0.2
chr4_6782371_6782522	0.33	KIAA0232	KIAA0232	1923	0.35
chr5_80303379_80303530	0.33	CTC-459I6.1		46728	0.15
chr3_67414091_67414242	0.33	SUCLG2	succinate-CoA ligase, GDP-forming, beta subunit	164480	0.04
chr8_22522608_22522841	0.33	BIN3	bridging integrator 3	3902	0.14
chrX_110341810_110342111	0.33	PAK3	p21 protein (Cdc42/Rac)-activated kinase 3	1345	0.61
chr12_48228347_48228498	0.33	HDAC7	histone deacetylase 7	1507	0.36
chr10_73837386_73837537	0.33	SPOCK2	sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2	10625	0.23
chr5_147161021_147161172	0.33	JAKMIP2	janus kinase and microtubule interacting protein 2	1009	0.61
chr11_111270234_111270480	0.32	ENSG00000253099	.	16540	0.12
chr7_50437351_50437502	0.32	ENSG00000200815	.	65652	0.11
chr5_52777524_52777793	0.32	FST	follistatin	1202	0.61
chr12_93757578_93757797	0.32	ENSG00000239073	.	13295	0.15
chr21_17196280_17196536	0.32	USP25	ubiquitin specific peptidase 25	921	0.72
chr16_50155409_50155560	0.32	RP11-429P3.5		370	0.83
chr10_11187609_11187800	0.32	CELF2	CUGBP, Elav-like family member 2	19289	0.19
chr1_214460978_214461129	0.32	SMYD2	SET and MYND domain containing 2	6477	0.3
chr9_117688687_117688838	0.32	TNFSF8	tumor necrosis factor (ligand) superfamily, member 8	3935	0.33
chr19_16371774_16371925	0.32	CTD-2562J15.6		32537	0.11

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of PAX4

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View png image

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.4	GO:0035405	histone-threonine phosphorylation(GO:0035405)
0.1	1.1	GO:0007172	signal complex assembly(GO:0007172)
0.1	0.5	GO:0033152	immunoglobulin V(D)J recombination(GO:0033152)
0.1	0.3	GO:0051573	negative regulation of histone H3-K9 methylation(GO:0051573)
0.1	0.3	GO:0030223	neutrophil differentiation(GO:0030223)
0.1	0.3	GO:0001831	trophectodermal cellular morphogenesis(GO:0001831)
0.1	0.2	GO:0006370	7-methylguanosine mRNA capping(GO:0006370)
0.1	0.3	GO:0021542	dentate gyrus development(GO:0021542)
0.1	0.3	GO:0061154	endothelial tube morphogenesis(GO:0061154)
0.1	0.3	GO:0051451	myoblast migration(GO:0051451)
0.1	0.3	GO:0036072	intramembranous ossification(GO:0001957) direct ossification(GO:0036072)
0.1	0.3	GO:0072182	nephron tubule epithelial cell differentiation(GO:0072160) regulation of nephron tubule epithelial cell differentiation(GO:0072182) regulation of epithelial cell differentiation involved in kidney development(GO:2000696)
0.1	0.2	GO:0001672	regulation of chromatin assembly or disassembly(GO:0001672)
0.1	0.2	GO:2000380	regulation of mesodermal cell fate specification(GO:0042661) regulation of mesoderm development(GO:2000380)
0.1	0.5	GO:0002710	negative regulation of T cell mediated immunity(GO:0002710)
0.1	0.2	GO:0018076	N-terminal peptidyl-lysine acetylation(GO:0018076)
0.1	0.2	GO:0031125	rRNA 3'-end processing(GO:0031125)
0.1	0.3	GO:0032237	activation of store-operated calcium channel activity(GO:0032237) regulation of store-operated calcium channel activity(GO:1901339) positive regulation of store-operated calcium channel activity(GO:1901341)
0.1	0.6	GO:0006491	N-glycan processing(GO:0006491)
0.1	0.2	GO:0030091	protein repair(GO:0030091)
0.1	0.3	GO:0033261	obsolete regulation of S phase(GO:0033261)
0.1	0.2	GO:0001543	ovarian follicle rupture(GO:0001543)
0.1	0.2	GO:0071921	establishment of sister chromatid cohesion(GO:0034085) cohesin loading(GO:0071921) regulation of cohesin loading(GO:0071922)
0.1	0.3	GO:0032926	negative regulation of activin receptor signaling pathway(GO:0032926)
0.1	0.1	GO:0032418	lysosome localization(GO:0032418)
0.1	0.2	GO:0042091	interleukin-10 biosynthetic process(GO:0042091) regulation of interleukin-10 biosynthetic process(GO:0045074)
0.1	0.1	GO:0051570	regulation of histone H3-K9 methylation(GO:0051570)
0.1	0.3	GO:0002726	positive regulation of T cell cytokine production(GO:0002726)
0.1	0.2	GO:0046137	negative regulation of calcidiol 1-monooxygenase activity(GO:0010956) negative regulation of vitamin D biosynthetic process(GO:0010957) negative regulation of vitamin metabolic process(GO:0046137)
0.1	0.3	GO:0030644	cellular chloride ion homeostasis(GO:0030644) chloride ion homeostasis(GO:0055064)
0.1	0.2	GO:0043276	anoikis(GO:0043276)
0.1	0.1	GO:0002513	tolerance induction to self antigen(GO:0002513)
0.1	0.2	GO:0006167	AMP biosynthetic process(GO:0006167)
0.1	0.4	GO:0045059	positive thymic T cell selection(GO:0045059)
0.1	0.1	GO:0045943	positive regulation of transcription from RNA polymerase I promoter(GO:0045943)
0.1	0.2	GO:0045722	positive regulation of gluconeogenesis(GO:0045722)
0.1	0.2	GO:0045162	clustering of voltage-gated sodium channels(GO:0045162)
0.1	0.2	GO:0043374	CD8-positive, alpha-beta T cell activation(GO:0036037) CD8-positive, alpha-beta T cell differentiation(GO:0043374)
0.1	0.4	GO:0060039	pericardium development(GO:0060039)
0.1	0.2	GO:0006065	UDP-glucuronate biosynthetic process(GO:0006065)
0.1	0.1	GO:0048537	mucosal-associated lymphoid tissue development(GO:0048537)
0.1	0.1	GO:0046398	UDP-glucuronate metabolic process(GO:0046398)
0.1	0.1	GO:1902745	positive regulation of lamellipodium assembly(GO:0010592) positive regulation of lamellipodium organization(GO:1902745)
0.1	0.5	GO:0006983	ER overload response(GO:0006983)
0.1	0.1	GO:0007352	zygotic specification of dorsal/ventral axis(GO:0007352)
0.1	0.1	GO:0002085	inhibition of neuroepithelial cell differentiation(GO:0002085)
0.1	0.2	GO:0010746	regulation of plasma membrane long-chain fatty acid transport(GO:0010746)
0.0	0.1	GO:0010831	positive regulation of myotube differentiation(GO:0010831)
0.0	0.1	GO:0015801	aromatic amino acid transport(GO:0015801)
0.0	0.1	GO:0090009	primitive streak formation(GO:0090009)
0.0	0.2	GO:0042989	sequestering of actin monomers(GO:0042989)
0.0	0.4	GO:0050872	white fat cell differentiation(GO:0050872)
0.0	0.1	GO:0006007	glucose catabolic process(GO:0006007)
0.0	0.1	GO:0001743	optic placode formation(GO:0001743)
0.0	0.2	GO:0032486	Rap protein signal transduction(GO:0032486)
0.0	0.2	GO:0043984	histone H4-K16 acetylation(GO:0043984)
0.0	0.1	GO:0060340	positive regulation of type I interferon-mediated signaling pathway(GO:0060340)
0.0	0.1	GO:0031665	negative regulation of lipopolysaccharide-mediated signaling pathway(GO:0031665)
0.0	0.0	GO:0002664	lymphocyte anergy(GO:0002249) T cell tolerance induction(GO:0002517) regulation of T cell tolerance induction(GO:0002664) positive regulation of T cell tolerance induction(GO:0002666) regulation of T cell anergy(GO:0002667) positive regulation of T cell anergy(GO:0002669) T cell anergy(GO:0002870) regulation of lymphocyte anergy(GO:0002911) positive regulation of lymphocyte anergy(GO:0002913)
0.0	0.2	GO:0071542	dopaminergic neuron differentiation(GO:0071542)
0.0	0.2	GO:0045329	amino-acid betaine biosynthetic process(GO:0006578) carnitine biosynthetic process(GO:0045329)
0.0	0.1	GO:0022038	corpus callosum development(GO:0022038)
0.0	0.1	GO:0021978	telencephalon regionalization(GO:0021978)
0.0	0.1	GO:0006189	'de novo' IMP biosynthetic process(GO:0006189)
0.0	0.1	GO:0031936	negative regulation of chromatin silencing(GO:0031936)
0.0	0.2	GO:0010837	regulation of keratinocyte proliferation(GO:0010837)
0.0	0.1	GO:0015917	aminophospholipid transport(GO:0015917)
0.0	0.1	GO:0001757	somite specification(GO:0001757)
0.0	0.0	GO:0060484	lung-associated mesenchyme development(GO:0060484)
0.0	0.2	GO:0043368	positive T cell selection(GO:0043368)
0.0	0.2	GO:0006020	inositol metabolic process(GO:0006020)
0.0	0.2	GO:0006924	activation-induced cell death of T cells(GO:0006924)
0.0	0.1	GO:0032876	regulation of DNA endoreduplication(GO:0032875) negative regulation of DNA endoreduplication(GO:0032876) DNA endoreduplication(GO:0042023)
0.0	0.5	GO:0019059	obsolete initiation of viral infection(GO:0019059)
0.0	0.0	GO:0090400	stress-induced premature senescence(GO:0090400)
0.0	0.1	GO:1903224	endodermal cell fate commitment(GO:0001711) endodermal cell fate specification(GO:0001714) endodermal cell differentiation(GO:0035987) regulation of endodermal cell fate specification(GO:0042663) regulation of endodermal cell differentiation(GO:1903224)
0.0	0.3	GO:0030206	chondroitin sulfate biosynthetic process(GO:0030206)
0.0	0.1	GO:0043320	natural killer cell activation involved in immune response(GO:0002323) natural killer cell degranulation(GO:0043320)
0.0	0.2	GO:0045647	negative regulation of erythrocyte differentiation(GO:0045647)
0.0	0.1	GO:0006089	lactate metabolic process(GO:0006089)
0.0	1.1	GO:0050690	regulation of defense response to virus by virus(GO:0050690)
0.0	0.1	GO:0010980	regulation of vitamin D 24-hydroxylase activity(GO:0010979) positive regulation of vitamin D 24-hydroxylase activity(GO:0010980)
0.0	0.1	GO:0001778	plasma membrane repair(GO:0001778)
0.0	0.1	GO:0032506	cytokinetic process(GO:0032506)
0.0	0.2	GO:0045672	positive regulation of osteoclast differentiation(GO:0045672)
0.0	0.4	GO:0007253	cytoplasmic sequestering of NF-kappaB(GO:0007253)
0.0	0.1	GO:0045589	regulation of regulatory T cell differentiation(GO:0045589)
0.0	0.1	GO:0046033	AMP metabolic process(GO:0046033)
0.0	0.1	GO:0010459	negative regulation of heart rate(GO:0010459)
0.0	0.2	GO:0007023	post-chaperonin tubulin folding pathway(GO:0007023)
0.0	0.0	GO:0021797	forebrain anterior/posterior pattern specification(GO:0021797)
0.0	0.1	GO:0060502	epithelial cell proliferation involved in lung morphogenesis(GO:0060502)
0.0	0.2	GO:0072202	cell differentiation involved in metanephros development(GO:0072202)
0.0	0.2	GO:2000144	positive regulation of transcription initiation from RNA polymerase II promoter(GO:0060261) positive regulation of DNA-templated transcription, initiation(GO:2000144)
0.0	0.1	GO:0002043	blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:0002043)
0.0	0.1	GO:0051665	membrane raft localization(GO:0051665)
0.0	0.1	GO:0016241	regulation of macroautophagy(GO:0016241)
0.0	0.1	GO:1903310	positive regulation of histone modification(GO:0031058) positive regulation of chromatin modification(GO:1903310)
0.0	0.2	GO:0006102	isocitrate metabolic process(GO:0006102)
0.0	0.1	GO:2000258	negative regulation of complement activation(GO:0045916) negative regulation of protein activation cascade(GO:2000258)
0.0	0.0	GO:0003207	cardiac chamber formation(GO:0003207) cardiac ventricle formation(GO:0003211)
0.0	0.2	GO:0090050	positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050) positive regulation of sprouting angiogenesis(GO:1903672)
0.0	0.1	GO:0044380	protein localization to cytoskeleton(GO:0044380) protein localization to microtubule cytoskeleton(GO:0072698)
0.0	0.2	GO:0006658	phosphatidylserine metabolic process(GO:0006658)
0.0	0.3	GO:0045885	obsolete positive regulation of survival gene product expression(GO:0045885)
0.0	0.4	GO:0006607	NLS-bearing protein import into nucleus(GO:0006607)
0.0	0.1	GO:0050862	positive regulation of T cell receptor signaling pathway(GO:0050862)
0.0	0.4	GO:0042273	ribosomal large subunit biogenesis(GO:0042273)
0.0	0.1	GO:0034392	negative regulation of smooth muscle cell apoptotic process(GO:0034392)
0.0	0.2	GO:0032232	negative regulation of actin filament bundle assembly(GO:0032232)
0.0	0.1	GO:0060648	mammary gland bud morphogenesis(GO:0060648)
0.0	0.0	GO:0033091	positive regulation of immature T cell proliferation(GO:0033091)
0.0	0.1	GO:2000758	positive regulation of histone acetylation(GO:0035066) positive regulation of protein acetylation(GO:1901985) positive regulation of peptidyl-lysine acetylation(GO:2000758)
0.0	0.1	GO:0033622	integrin activation(GO:0033622)
0.0	0.2	GO:0034314	Arp2/3 complex-mediated actin nucleation(GO:0034314)
0.0	0.5	GO:0032012	regulation of ARF protein signal transduction(GO:0032012)
0.0	0.1	GO:0014067	negative regulation of phosphatidylinositol 3-kinase signaling(GO:0014067)
0.0	0.1	GO:0046831	regulation of RNA export from nucleus(GO:0046831)
0.0	0.0	GO:0051386	regulation of neurotrophin TRK receptor signaling pathway(GO:0051386)
0.0	0.1	GO:0032927	positive regulation of activin receptor signaling pathway(GO:0032927)
0.0	0.0	GO:0060435	bronchiole development(GO:0060435)
0.0	0.1	GO:0070682	proteasome regulatory particle assembly(GO:0070682)
0.0	0.2	GO:0009103	lipopolysaccharide biosynthetic process(GO:0009103)
0.0	0.4	GO:0042226	interleukin-6 biosynthetic process(GO:0042226)
0.0	0.1	GO:0002019	regulation of renal output by angiotensin(GO:0002019)
0.0	0.7	GO:0007052	mitotic spindle organization(GO:0007052)
0.0	0.1	GO:0045332	lipid translocation(GO:0034204) phospholipid translocation(GO:0045332)
0.0	0.1	GO:0072526	pyridine-containing compound catabolic process(GO:0072526)
0.0	0.0	GO:0034086	maintenance of sister chromatid cohesion(GO:0034086) maintenance of mitotic sister chromatid cohesion(GO:0034088)
0.0	0.3	GO:0016446	somatic diversification of immune receptors via somatic mutation(GO:0002566) somatic hypermutation of immunoglobulin genes(GO:0016446)
0.0	0.1	GO:0006420	arginyl-tRNA aminoacylation(GO:0006420)
0.0	0.3	GO:0032456	endocytic recycling(GO:0032456)
0.0	0.1	GO:0042178	xenobiotic catabolic process(GO:0042178)
0.0	0.0	GO:0045347	negative regulation of MHC class II biosynthetic process(GO:0045347)
0.0	0.1	GO:0046121	deoxyribonucleoside catabolic process(GO:0046121)
0.0	0.2	GO:0001561	fatty acid alpha-oxidation(GO:0001561)
0.0	0.1	GO:0002423	natural killer cell mediated cytotoxicity directed against tumor cell target(GO:0002420) natural killer cell mediated immune response to tumor cell(GO:0002423) regulation of natural killer cell mediated immune response to tumor cell(GO:0002855) positive regulation of natural killer cell mediated immune response to tumor cell(GO:0002857) regulation of natural killer cell mediated cytotoxicity directed against tumor cell target(GO:0002858) positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target(GO:0002860)
0.0	0.1	GO:0051532	NFAT protein import into nucleus(GO:0051531) regulation of NFAT protein import into nucleus(GO:0051532)
0.0	0.0	GO:0048478	replication fork protection(GO:0048478)
0.0	0.2	GO:0060736	prostate gland growth(GO:0060736)
0.0	0.1	GO:0006828	manganese ion transport(GO:0006828)
0.0	0.1	GO:0071636	positive regulation of transforming growth factor beta production(GO:0071636)
0.0	0.1	GO:0009128	purine nucleoside monophosphate catabolic process(GO:0009128) ribonucleoside monophosphate catabolic process(GO:0009158) purine ribonucleoside monophosphate catabolic process(GO:0009169)
0.0	0.1	GO:0034755	iron ion transmembrane transport(GO:0034755)
0.0	0.3	GO:0043616	keratinocyte proliferation(GO:0043616)
0.0	0.2	GO:0007216	G-protein coupled glutamate receptor signaling pathway(GO:0007216)
0.0	0.2	GO:0015840	urea transport(GO:0015840)
0.0	0.1	GO:1903312	negative regulation of mRNA processing(GO:0050686) negative regulation of mRNA metabolic process(GO:1903312)
0.0	0.1	GO:0003402	planar cell polarity pathway involved in axis elongation(GO:0003402)
0.0	0.1	GO:0045767	obsolete regulation of anti-apoptosis(GO:0045767)
0.0	0.0	GO:0043247	protection from non-homologous end joining at telomere(GO:0031848) telomere maintenance in response to DNA damage(GO:0043247)
0.0	0.1	GO:0009405	pathogenesis(GO:0009405)
0.0	0.4	GO:0042771	intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator(GO:0042771)
0.0	0.2	GO:0046339	diacylglycerol metabolic process(GO:0046339)
0.0	0.0	GO:0002864	regulation of acute inflammatory response to antigenic stimulus(GO:0002864)
0.0	0.1	GO:0000389	mRNA 3'-splice site recognition(GO:0000389)
0.0	0.1	GO:0043267	negative regulation of potassium ion transport(GO:0043267)
0.0	0.3	GO:0043968	histone H2A acetylation(GO:0043968)
0.0	0.1	GO:0050849	negative regulation of calcium-mediated signaling(GO:0050849)
0.0	0.1	GO:0002691	regulation of cellular extravasation(GO:0002691)
0.0	0.1	GO:0070198	protein localization to chromosome, telomeric region(GO:0070198)
0.0	0.1	GO:0010452	histone H3-K36 methylation(GO:0010452)
0.0	0.1	GO:0003310	pancreatic A cell differentiation(GO:0003310)
0.0	0.1	GO:1901419	regulation of response to alcohol(GO:1901419)
0.0	0.1	GO:0043951	negative regulation of cAMP-mediated signaling(GO:0043951)
0.0	0.2	GO:0045086	positive regulation of interleukin-2 biosynthetic process(GO:0045086)
0.0	0.0	GO:0001821	histamine secretion(GO:0001821)
0.0	0.0	GO:0042415	norepinephrine metabolic process(GO:0042415)
0.0	0.2	GO:0060216	definitive hemopoiesis(GO:0060216)
0.0	0.1	GO:0021530	spinal cord oligodendrocyte cell differentiation(GO:0021529) spinal cord oligodendrocyte cell fate specification(GO:0021530) oligodendrocyte cell fate specification(GO:0021778) glial cell fate specification(GO:0021780)
0.0	0.2	GO:0006670	sphingosine metabolic process(GO:0006670)
0.0	0.1	GO:0002335	mature B cell differentiation(GO:0002335)
0.0	0.1	GO:0045046	protein import into peroxisome membrane(GO:0045046)
0.0	0.1	GO:0016584	nucleosome positioning(GO:0016584)
0.0	0.1	GO:0050665	hydrogen peroxide biosynthetic process(GO:0050665)
0.0	0.1	GO:0010107	potassium ion import(GO:0010107)
0.0	0.2	GO:0034453	microtubule anchoring(GO:0034453)
0.0	0.1	GO:0045990	carbon catabolite regulation of transcription(GO:0045990) regulation of transcription by glucose(GO:0046015)
0.0	0.1	GO:0045163	clustering of voltage-gated potassium channels(GO:0045163)
0.0	0.3	GO:0000380	alternative mRNA splicing, via spliceosome(GO:0000380)
0.0	0.1	GO:0050858	negative regulation of antigen receptor-mediated signaling pathway(GO:0050858) negative regulation of T cell receptor signaling pathway(GO:0050860)
0.0	0.3	GO:0098743	cartilage condensation(GO:0001502) cell aggregation(GO:0098743)
0.0	0.1	GO:0060605	tube lumen cavitation(GO:0060605) salivary gland cavitation(GO:0060662)
0.0	0.1	GO:0035335	peptidyl-tyrosine dephosphorylation(GO:0035335)
0.0	0.2	GO:0045843	negative regulation of striated muscle tissue development(GO:0045843)
0.0	0.0	GO:0090224	regulation of spindle organization(GO:0090224)
0.0	0.0	GO:0010216	maintenance of DNA methylation(GO:0010216)
0.0	0.1	GO:0045648	positive regulation of erythrocyte differentiation(GO:0045648)
0.0	0.2	GO:0050853	B cell receptor signaling pathway(GO:0050853)
0.0	0.0	GO:0032650	regulation of interleukin-1 alpha production(GO:0032650) positive regulation of interleukin-1 alpha production(GO:0032730)
0.0	0.2	GO:0016558	protein import into peroxisome matrix(GO:0016558)
0.0	0.0	GO:0000733	DNA strand renaturation(GO:0000733)
0.0	0.0	GO:0060235	olfactory placode formation(GO:0030910) lens induction in camera-type eye(GO:0060235) olfactory placode development(GO:0071698) olfactory placode morphogenesis(GO:0071699)
0.0	0.1	GO:1902583	multi-organism transport(GO:0044766) transport of virus(GO:0046794) intracellular transport of virus(GO:0075733) multi-organism localization(GO:1902579) multi-organism intracellular transport(GO:1902583)
0.0	0.2	GO:0071108	protein K48-linked deubiquitination(GO:0071108)
0.0	0.3	GO:0043124	negative regulation of I-kappaB kinase/NF-kappaB signaling(GO:0043124)
0.0	0.0	GO:0060068	vagina development(GO:0060068)
0.0	0.1	GO:0006269	DNA replication, synthesis of RNA primer(GO:0006269)
0.0	0.0	GO:0071243	cellular response to arsenic-containing substance(GO:0071243)
0.0	0.2	GO:0009713	catechol-containing compound biosynthetic process(GO:0009713) catecholamine biosynthetic process(GO:0042423)
0.0	0.2	GO:0048013	ephrin receptor signaling pathway(GO:0048013)
0.0	0.7	GO:0042059	negative regulation of epidermal growth factor receptor signaling pathway(GO:0042059) negative regulation of ERBB signaling pathway(GO:1901185)
0.0	0.1	GO:0060292	long term synaptic depression(GO:0060292)
0.0	0.1	GO:0014052	regulation of gamma-aminobutyric acid secretion(GO:0014052)
0.0	0.2	GO:0046885	regulation of hormone biosynthetic process(GO:0046885)
0.0	0.2	GO:0035964	COPI-coated vesicle budding(GO:0035964) Golgi vesicle budding(GO:0048194) Golgi transport vesicle coating(GO:0048200) COPI coating of Golgi vesicle(GO:0048205)
0.0	0.1	GO:0007035	vacuolar acidification(GO:0007035)
0.0	0.1	GO:1901623	T cell chemotaxis(GO:0010818) regulation of T cell chemotaxis(GO:0010819) positive regulation of T cell chemotaxis(GO:0010820) regulation of lymphocyte chemotaxis(GO:1901623) regulation of lymphocyte migration(GO:2000401) positive regulation of lymphocyte migration(GO:2000403) regulation of T cell migration(GO:2000404) positive regulation of T cell migration(GO:2000406)
0.0	0.2	GO:0042994	cytoplasmic sequestering of transcription factor(GO:0042994)
0.0	0.0	GO:0033147	negative regulation of intracellular estrogen receptor signaling pathway(GO:0033147)
0.0	0.0	GO:0046007	negative regulation of activated T cell proliferation(GO:0046007)
0.0	0.1	GO:0000185	activation of MAPKKK activity(GO:0000185)
0.0	0.1	GO:0031167	rRNA methylation(GO:0031167)
0.0	0.0	GO:0002407	dendritic cell chemotaxis(GO:0002407) dendritic cell migration(GO:0036336)
0.0	0.1	GO:0070837	dehydroascorbic acid transport(GO:0070837)
0.0	0.1	GO:0046130	purine nucleoside catabolic process(GO:0006152) purine ribonucleoside catabolic process(GO:0046130)
0.0	0.1	GO:0006422	aspartyl-tRNA aminoacylation(GO:0006422)
0.0	0.5	GO:0000080	mitotic G1 phase(GO:0000080)
0.0	0.0	GO:0010534	regulation of activation of JAK2 kinase activity(GO:0010534) positive regulation of activation of JAK2 kinase activity(GO:0010535)
0.0	0.0	GO:0031536	positive regulation of exit from mitosis(GO:0031536)
0.0	0.0	GO:0051798	positive regulation of hair cycle(GO:0042635) positive regulation of hair follicle development(GO:0051798)
0.0	0.1	GO:0030502	negative regulation of bone mineralization(GO:0030502)
0.0	0.1	GO:0046607	positive regulation of centrosome cycle(GO:0046607)
0.0	0.1	GO:0030186	melatonin metabolic process(GO:0030186) melatonin biosynthetic process(GO:0030187)
0.0	0.1	GO:0008089	anterograde axonal transport(GO:0008089)
0.0	0.0	GO:0071166	ribonucleoprotein complex localization(GO:0071166)
0.0	0.1	GO:0019885	antigen processing and presentation of endogenous peptide antigen(GO:0002483) antigen processing and presentation of endogenous peptide antigen via MHC class I(GO:0019885)
0.0	0.1	GO:0006451	selenocysteine incorporation(GO:0001514) translational readthrough(GO:0006451)
0.0	0.2	GO:0032008	positive regulation of TOR signaling(GO:0032008)
0.0	0.2	GO:0042987	amyloid precursor protein catabolic process(GO:0042987)
0.0	0.0	GO:0000154	rRNA modification(GO:0000154)
0.0	0.0	GO:0060242	contact inhibition(GO:0060242)
0.0	0.3	GO:0046854	phosphatidylinositol phosphorylation(GO:0046854)
0.0	0.1	GO:0018243	protein O-linked glycosylation via serine(GO:0018242) protein O-linked glycosylation via threonine(GO:0018243)
0.0	0.1	GO:0070536	protein K63-linked deubiquitination(GO:0070536)
0.0	0.2	GO:0060765	regulation of androgen receptor signaling pathway(GO:0060765)
0.0	0.1	GO:0009215	purine deoxyribonucleoside triphosphate metabolic process(GO:0009215)
0.0	0.3	GO:0016925	protein sumoylation(GO:0016925)
0.0	0.1	GO:0007090	obsolete regulation of S phase of mitotic cell cycle(GO:0007090)
0.0	0.1	GO:0045084	positive regulation of interleukin-12 biosynthetic process(GO:0045084)
0.0	0.1	GO:1902750	negative regulation of G2/M transition of mitotic cell cycle(GO:0010972) negative regulation of cell cycle G2/M phase transition(GO:1902750)
0.0	0.1	GO:0021570	rhombomere 4 development(GO:0021570)
0.0	0.0	GO:0002523	leukocyte migration involved in inflammatory response(GO:0002523)
0.0	0.1	GO:0070389	chaperone cofactor-dependent protein refolding(GO:0070389)
0.0	0.2	GO:0000076	DNA replication checkpoint(GO:0000076)
0.0	0.0	GO:0035162	embryonic hemopoiesis(GO:0035162)
0.0	0.0	GO:0042510	regulation of tyrosine phosphorylation of Stat1 protein(GO:0042510)
0.0	0.1	GO:0008291	acetylcholine metabolic process(GO:0008291) acetate ester metabolic process(GO:1900619)
0.0	0.1	GO:0000089	mitotic metaphase(GO:0000089)
0.0	0.0	GO:0034311	sphinganine metabolic process(GO:0006667) diol metabolic process(GO:0034311)
0.0	0.1	GO:0010257	NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.0	0.8	GO:0050852	T cell receptor signaling pathway(GO:0050852)
0.0	0.1	GO:0001574	ganglioside biosynthetic process(GO:0001574)
0.0	0.1	GO:0071392	cellular response to estradiol stimulus(GO:0071392)
0.0	0.1	GO:2001257	regulation of calcium ion transmembrane transporter activity(GO:1901019) regulation of cation channel activity(GO:2001257)
0.0	0.1	GO:0010508	positive regulation of autophagy(GO:0010508)
0.0	0.1	GO:0046185	aldehyde catabolic process(GO:0046185)
0.0	0.0	GO:0043353	enucleate erythrocyte differentiation(GO:0043353)
0.0	0.0	GO:0002837	regulation of response to tumor cell(GO:0002834) positive regulation of response to tumor cell(GO:0002836) regulation of immune response to tumor cell(GO:0002837) positive regulation of immune response to tumor cell(GO:0002839)
0.0	0.1	GO:0060762	regulation of branching involved in mammary gland duct morphogenesis(GO:0060762)
0.0	0.1	GO:0016572	histone phosphorylation(GO:0016572)
0.0	0.0	GO:0015015	heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.0	0.1	GO:0043392	negative regulation of DNA binding(GO:0043392)
0.0	0.1	GO:0060710	chorio-allantoic fusion(GO:0060710)
0.0	0.1	GO:0034219	carbohydrate transmembrane transport(GO:0034219)
0.0	0.4	GO:0042147	retrograde transport, endosome to Golgi(GO:0042147)
0.0	0.1	GO:0009048	dosage compensation by inactivation of X chromosome(GO:0009048)
0.0	0.1	GO:0000183	chromatin silencing at rDNA(GO:0000183)
0.0	0.2	GO:0010921	regulation of phosphatase activity(GO:0010921)
0.0	0.0	GO:0071043	CUT catabolic process(GO:0071034) CUT metabolic process(GO:0071043)
0.0	0.1	GO:0045071	negative regulation of viral genome replication(GO:0045071)
0.0	0.1	GO:0032988	ribonucleoprotein complex disassembly(GO:0032988)
0.0	0.0	GO:0071428	rRNA-containing ribonucleoprotein complex export from nucleus(GO:0071428)
0.0	0.1	GO:0098927	early endosome to late endosome transport(GO:0045022) vesicle-mediated transport between endosomal compartments(GO:0098927)
0.0	0.0	GO:0001911	negative regulation of leukocyte mediated cytotoxicity(GO:0001911)
0.0	0.1	GO:0009822	alkaloid catabolic process(GO:0009822)
0.0	0.0	GO:0019060	intracellular transport of viral protein in host cell(GO:0019060) symbiont intracellular protein transport in host(GO:0030581) regulation by virus of viral protein levels in host cell(GO:0046719) intracellular protein transport in other organism involved in symbiotic interaction(GO:0051708)
0.0	0.1	GO:0006379	mRNA cleavage(GO:0006379)
0.0	0.0	GO:0033119	negative regulation of RNA splicing(GO:0033119)
0.0	0.1	GO:0045956	positive regulation of calcium ion-dependent exocytosis(GO:0045956)
0.0	0.1	GO:0033345	asparagine catabolic process(GO:0006530) asparagine catabolic process via L-aspartate(GO:0033345)
0.0	0.1	GO:0070071	proton-transporting two-sector ATPase complex assembly(GO:0070071)
0.0	0.1	GO:0033169	histone H3-K9 demethylation(GO:0033169)
0.0	0.0	GO:0006922	obsolete cleavage of lamin involved in execution phase of apoptosis(GO:0006922)
0.0	0.2	GO:0042776	mitochondrial ATP synthesis coupled proton transport(GO:0042776)
0.0	0.1	GO:0008635	activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c(GO:0008635)
0.0	0.0	GO:0030854	positive regulation of granulocyte differentiation(GO:0030854)
0.0	0.1	GO:0046502	uroporphyrinogen III metabolic process(GO:0046502)
0.0	0.1	GO:0007000	nucleolus organization(GO:0007000)
0.0	0.0	GO:0042362	fat-soluble vitamin biosynthetic process(GO:0042362)
0.0	0.0	GO:0070366	regulation of hepatocyte differentiation(GO:0070366)
0.0	0.1	GO:0035020	regulation of Rac protein signal transduction(GO:0035020)
0.0	0.1	GO:0015705	iodide transport(GO:0015705)
0.0	0.1	GO:0009138	pyrimidine nucleoside diphosphate metabolic process(GO:0009138)
0.0	0.1	GO:0014037	Schwann cell differentiation(GO:0014037)
0.0	0.1	GO:0060158	phospholipase C-activating dopamine receptor signaling pathway(GO:0060158)
0.0	0.0	GO:0030263	apoptotic chromosome condensation(GO:0030263)
0.0	0.0	GO:0071168	protein localization to chromatin(GO:0071168)
0.0	0.4	GO:0070936	protein K48-linked ubiquitination(GO:0070936)
0.0	0.0	GO:0048262	determination of dorsal/ventral asymmetry(GO:0048262) determination of dorsal identity(GO:0048263)
0.0	0.2	GO:0010039	response to iron ion(GO:0010039)
0.0	0.1	GO:0048821	erythrocyte development(GO:0048821) myeloid cell development(GO:0061515)
0.0	0.0	GO:0006998	nuclear envelope organization(GO:0006998)
0.0	0.0	GO:0071391	cellular response to estrogen stimulus(GO:0071391)
0.0	0.0	GO:0032071	regulation of endodeoxyribonuclease activity(GO:0032071)
0.0	0.1	GO:0070265	necrotic cell death(GO:0070265)
0.0	0.0	GO:0016093	polyprenol metabolic process(GO:0016093) dolichol metabolic process(GO:0019348)
0.0	0.0	GO:0043568	positive regulation of insulin-like growth factor receptor signaling pathway(GO:0043568)
0.0	0.3	GO:0034199	activation of protein kinase A activity(GO:0034199)
0.0	0.0	GO:0070365	hepatocyte differentiation(GO:0070365)
0.0	0.0	GO:0045056	transcytosis(GO:0045056)
0.0	0.1	GO:0046952	ketone body catabolic process(GO:0046952)
0.0	0.0	GO:0033173	calcineurin-NFAT signaling cascade(GO:0033173)
0.0	0.1	GO:0032986	nucleosome disassembly(GO:0006337) chromatin disassembly(GO:0031498) protein-DNA complex disassembly(GO:0032986)
0.0	0.0	GO:0046084	purine ribonucleoside salvage(GO:0006166) adenine salvage(GO:0006168) purine nucleobase salvage(GO:0043096) adenine metabolic process(GO:0046083) adenine biosynthetic process(GO:0046084)
0.0	0.0	GO:0060049	regulation of protein glycosylation(GO:0060049)
0.0	0.0	GO:0009301	snRNA transcription(GO:0009301)
0.0	0.0	GO:0045759	negative regulation of action potential(GO:0045759)
0.0	0.0	GO:0043628	ncRNA 3'-end processing(GO:0043628)
0.0	0.0	GO:0006610	ribosomal protein import into nucleus(GO:0006610)
0.0	0.3	GO:0043044	ATP-dependent chromatin remodeling(GO:0043044)
0.0	0.0	GO:0006346	methylation-dependent chromatin silencing(GO:0006346)
0.0	0.2	GO:0045143	homologous chromosome segregation(GO:0045143)
0.0	0.0	GO:0034421	post-translational protein acetylation(GO:0034421)
0.0	0.1	GO:0035434	copper ion transmembrane transport(GO:0035434)
0.0	0.1	GO:0046487	glyoxylate metabolic process(GO:0046487)
0.0	0.1	GO:0051965	positive regulation of synapse assembly(GO:0051965)
0.0	0.1	GO:0097191	extrinsic apoptotic signaling pathway via death domain receptors(GO:0008625) extrinsic apoptotic signaling pathway(GO:0097191)
0.0	0.4	GO:0051017	actin filament bundle assembly(GO:0051017) actin filament bundle organization(GO:0061572)
0.0	0.0	GO:0016056	rhodopsin mediated signaling pathway(GO:0016056)
0.0	0.0	GO:0006930	substrate-dependent cell migration, cell extension(GO:0006930)
0.0	0.0	GO:0035455	response to interferon-alpha(GO:0035455)
0.0	0.0	GO:0098870	neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870)
0.0	0.4	GO:0000245	spliceosomal complex assembly(GO:0000245)
0.0	0.1	GO:0071027	RNA surveillance(GO:0071025) nuclear RNA surveillance(GO:0071027) nuclear mRNA surveillance(GO:0071028)
0.0	0.0	GO:0060065	uterus development(GO:0060065)
0.0	0.0	GO:0046519	sphingoid metabolic process(GO:0046519)
0.0	0.1	GO:0042518	negative regulation of tyrosine phosphorylation of Stat3 protein(GO:0042518)
0.0	0.0	GO:0002374	cytokine secretion involved in immune response(GO:0002374) regulation of cytokine secretion involved in immune response(GO:0002739) negative regulation of cytokine secretion involved in immune response(GO:0002740)
0.0	0.2	GO:0045576	mast cell activation(GO:0045576)
0.0	0.1	GO:0031648	protein destabilization(GO:0031648)
0.0	0.2	GO:0070979	protein K11-linked ubiquitination(GO:0070979)
0.0	0.0	GO:0014010	Schwann cell proliferation(GO:0014010)
0.0	0.1	GO:0017182	peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183)
0.0	0.0	GO:0031342	negative regulation of cell killing(GO:0031342)
0.0	0.0	GO:0048304	positive regulation of isotype switching to IgG isotypes(GO:0048304)
0.0	0.1	GO:0051101	regulation of DNA binding(GO:0051101)
0.0	0.1	GO:0060330	regulation of response to interferon-gamma(GO:0060330) regulation of interferon-gamma-mediated signaling pathway(GO:0060334)
0.0	0.1	GO:0009261	ribonucleotide catabolic process(GO:0009261)
0.0	0.0	GO:0009189	deoxyribonucleoside diphosphate biosynthetic process(GO:0009189)
0.0	0.1	GO:0048536	spleen development(GO:0048536)
0.0	0.1	GO:0043545	Mo-molybdopterin cofactor biosynthetic process(GO:0006777) Mo-molybdopterin cofactor metabolic process(GO:0019720) molybdopterin cofactor biosynthetic process(GO:0032324) molybdopterin cofactor metabolic process(GO:0043545) prosthetic group metabolic process(GO:0051189)
0.0	0.0	GO:0034214	protein hexamerization(GO:0034214)
0.0	0.0	GO:0032075	positive regulation of nuclease activity(GO:0032075)
0.0	0.0	GO:0046621	negative regulation of organ growth(GO:0046621)
0.0	0.5	GO:0050434	positive regulation of viral transcription(GO:0050434)
0.0	0.1	GO:0007210	serotonin receptor signaling pathway(GO:0007210)
0.0	0.1	GO:0051568	histone H3-K4 methylation(GO:0051568)
0.0	0.1	GO:0015904	tetracycline transport(GO:0015904)
0.0	0.0	GO:0034063	stress granule assembly(GO:0034063)
0.0	0.0	GO:0032497	detection of lipopolysaccharide(GO:0032497)
0.0	0.1	GO:0000303	response to superoxide(GO:0000303)
0.0	0.1	GO:0018206	peptidyl-methionine modification(GO:0018206)
0.0	0.0	GO:0044240	multicellular organism lipid catabolic process(GO:0044240)
0.0	0.6	GO:0006406	mRNA export from nucleus(GO:0006406) mRNA-containing ribonucleoprotein complex export from nucleus(GO:0071427)
0.0	0.0	GO:0032413	negative regulation of ion transmembrane transporter activity(GO:0032413)
0.0	0.1	GO:0046037	GMP metabolic process(GO:0046037)
0.0	0.1	GO:0046856	phosphatidylinositol dephosphorylation(GO:0046856)
0.0	0.0	GO:0090399	replicative senescence(GO:0090399)
0.0	0.0	GO:0072070	loop of Henle development(GO:0072070)
0.0	0.0	GO:0008653	lipopolysaccharide metabolic process(GO:0008653)
0.0	0.0	GO:0015919	peroxisomal membrane transport(GO:0015919)
0.0	0.0	GO:0070508	sterol import(GO:0035376) cholesterol import(GO:0070508)
0.0	0.1	GO:0032784	regulation of DNA-templated transcription, elongation(GO:0032784)
0.0	0.2	GO:0070664	negative regulation of leukocyte proliferation(GO:0070664)
0.0	0.1	GO:0050962	detection of light stimulus involved in visual perception(GO:0050908) detection of light stimulus involved in sensory perception(GO:0050962)
0.0	0.0	GO:0048859	formation of anatomical boundary(GO:0048859)
0.0	0.0	GO:0060707	trophoblast giant cell differentiation(GO:0060707)
0.0	0.0	GO:0001302	replicative cell aging(GO:0001302)
0.0	0.0	GO:0031282	regulation of guanylate cyclase activity(GO:0031282)
0.0	0.1	GO:0045652	regulation of megakaryocyte differentiation(GO:0045652) regulation of hematopoietic progenitor cell differentiation(GO:1901532)
0.0	0.0	GO:0071426	ribonucleoprotein complex export from nucleus(GO:0071426)
0.0	0.0	GO:0090195	chemokine secretion(GO:0090195) regulation of chemokine secretion(GO:0090196) positive regulation of chemokine secretion(GO:0090197)
0.0	0.1	GO:0006538	glutamate catabolic process(GO:0006538)
0.0	0.1	GO:0032228	regulation of synaptic transmission, GABAergic(GO:0032228)
0.0	0.0	GO:0042447	hormone catabolic process(GO:0042447)
0.0	0.1	GO:0015695	organic cation transport(GO:0015695)
0.0	0.1	GO:0097480	synaptic vesicle transport(GO:0048489) synaptic vesicle localization(GO:0097479) establishment of synaptic vesicle localization(GO:0097480)
0.0	0.0	GO:0061030	epithelial cell differentiation involved in mammary gland alveolus development(GO:0061030)
0.0	0.1	GO:0032091	negative regulation of protein binding(GO:0032091)
0.0	0.0	GO:0016075	rRNA catabolic process(GO:0016075)
0.0	0.0	GO:0060123	regulation of growth hormone secretion(GO:0060123)
0.0	0.0	GO:0010507	negative regulation of autophagy(GO:0010507)
0.0	0.0	GO:0010823	negative regulation of mitochondrion organization(GO:0010823) negative regulation of release of cytochrome c from mitochondria(GO:0090201) negative regulation of apoptotic signaling pathway(GO:2001234)
0.0	0.0	GO:0072189	ureter development(GO:0072189)
0.0	0.4	GO:0006338	chromatin remodeling(GO:0006338)
0.0	0.0	GO:0008053	mitochondrial fusion(GO:0008053)
0.0	0.0	GO:0019883	antigen processing and presentation of endogenous antigen(GO:0019883)
0.0	0.0	GO:0042219	cellular modified amino acid catabolic process(GO:0042219)
0.0	0.0	GO:0035024	negative regulation of Rho protein signal transduction(GO:0035024)
0.0	0.0	GO:0060743	epithelial cell maturation involved in prostate gland development(GO:0060743)
0.0	0.0	GO:0043268	positive regulation of potassium ion transport(GO:0043268)
0.0	0.0	GO:0030505	inorganic diphosphate transport(GO:0030505)
0.0	0.2	GO:0031294	lymphocyte costimulation(GO:0031294) T cell costimulation(GO:0031295)
0.0	0.0	GO:0033131	regulation of glucokinase activity(GO:0033131) positive regulation of glucokinase activity(GO:0033133) regulation of hexokinase activity(GO:1903299) positive regulation of hexokinase activity(GO:1903301)
0.0	0.0	GO:0003148	outflow tract septum morphogenesis(GO:0003148)
0.0	0.0	GO:0000492	small nucleolar ribonucleoprotein complex assembly(GO:0000491) box C/D snoRNP assembly(GO:0000492)
0.0	0.3	GO:0006626	protein targeting to mitochondrion(GO:0006626)
0.0	0.2	GO:0016574	histone ubiquitination(GO:0016574)
0.0	0.0	GO:0046877	regulation of saliva secretion(GO:0046877)
0.0	0.1	GO:0006477	protein sulfation(GO:0006477)
0.0	0.0	GO:0035511	oxidative DNA demethylation(GO:0035511)
0.0	0.1	GO:0044273	sulfur compound catabolic process(GO:0044273)
0.0	0.0	GO:0071224	cellular response to peptidoglycan(GO:0071224)
0.0	0.1	GO:0007213	G-protein coupled acetylcholine receptor signaling pathway(GO:0007213) acetylcholine receptor signaling pathway(GO:0095500) postsynaptic signal transduction(GO:0098926) signal transduction involved in cellular response to ammonium ion(GO:1903831) response to acetylcholine(GO:1905144) cellular response to acetylcholine(GO:1905145)
0.0	0.0	GO:0007144	female meiosis I(GO:0007144)
0.0	0.0	GO:0032097	positive regulation of response to food(GO:0032097) positive regulation of appetite(GO:0032100)
0.0	0.0	GO:1903332	regulation of protein folding(GO:1903332)
0.0	0.2	GO:0008633	obsolete activation of pro-apoptotic gene products(GO:0008633)
0.0	0.0	GO:0016081	synaptic vesicle docking(GO:0016081)
0.0	0.4	GO:0006120	mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.0	0.0	GO:0010591	regulation of lamellipodium assembly(GO:0010591) regulation of lamellipodium organization(GO:1902743)
0.0	0.1	GO:0035121	obsolete tail morphogenesis(GO:0035121)
0.0	0.0	GO:0018343	protein farnesylation(GO:0018343)
0.0	0.1	GO:0033540	fatty acid beta-oxidation using acyl-CoA oxidase(GO:0033540)
0.0	0.0	GO:0050917	sensory perception of umami taste(GO:0050917)
0.0	0.0	GO:0048496	maintenance of organ identity(GO:0048496)
0.0	0.0	GO:0035609	C-terminal protein deglutamylation(GO:0035609) protein side chain deglutamylation(GO:0035610)
0.0	1.2	GO:0000377	RNA splicing, via transesterification reactions with bulged adenosine as nucleophile(GO:0000377) mRNA splicing, via spliceosome(GO:0000398)
0.0	0.3	GO:0071805	cellular potassium ion transport(GO:0071804) potassium ion transmembrane transport(GO:0071805)
0.0	0.1	GO:0016079	synaptic vesicle exocytosis(GO:0016079)
0.0	0.1	GO:0006553	lysine metabolic process(GO:0006553) lysine catabolic process(GO:0006554)
0.0	0.1	GO:0097581	lamellipodium assembly(GO:0030032) lamellipodium organization(GO:0097581)
0.0	0.0	GO:0055015	ventricular cardiac muscle cell development(GO:0055015)
0.0	0.0	GO:0001306	age-dependent response to oxidative stress(GO:0001306) age-dependent general metabolic decline(GO:0007571)
0.0	0.2	GO:0016236	macroautophagy(GO:0016236)
0.0	0.0	GO:0035092	sperm chromatin condensation(GO:0035092)
0.0	0.2	GO:0051925	obsolete regulation of calcium ion transport via voltage-gated calcium channel activity(GO:0051925)
0.0	0.1	GO:0032119	sequestering of zinc ion(GO:0032119)
0.0	0.7	GO:0035023	regulation of Rho protein signal transduction(GO:0035023)
0.0	0.0	GO:0060760	positive regulation of response to cytokine stimulus(GO:0060760)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.4	GO:0042105	alpha-beta T cell receptor complex(GO:0042105)
0.1	0.2	GO:0072487	MSL complex(GO:0072487)
0.1	0.6	GO:0001891	phagocytic cup(GO:0001891)
0.1	0.2	GO:0005686	U2 snRNP(GO:0005686)
0.1	0.4	GO:0001931	uropod(GO:0001931) cell trailing edge(GO:0031254)
0.1	0.6	GO:0030877	beta-catenin destruction complex(GO:0030877)
0.1	0.2	GO:0070022	transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.1	0.3	GO:0016589	NURF complex(GO:0016589)
0.1	0.2	GO:0031265	CD95 death-inducing signaling complex(GO:0031265)
0.1	0.3	GO:0005797	Golgi medial cisterna(GO:0005797)
0.0	0.1	GO:0034673	inhibin-betaglycan-ActRII complex(GO:0034673)
0.0	0.2	GO:0071204	histone pre-mRNA 3'end processing complex(GO:0071204)
0.0	0.2	GO:0072669	tRNA-splicing ligase complex(GO:0072669)
0.0	0.2	GO:0031465	Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
0.0	0.3	GO:0072357	PTW/PP1 phosphatase complex(GO:0072357)
0.0	0.1	GO:0031264	death-inducing signaling complex(GO:0031264)
0.0	0.2	GO:0005828	kinetochore microtubule(GO:0005828)
0.0	0.1	GO:0005784	Sec61 translocon complex(GO:0005784) translocon complex(GO:0071256)
0.0	0.1	GO:1990316	ATG1/ULK1 kinase complex(GO:1990316)
0.0	0.4	GO:0010494	cytoplasmic stress granule(GO:0010494)
0.0	0.2	GO:0014731	spectrin-associated cytoskeleton(GO:0014731)
0.0	0.2	GO:0000800	lateral element(GO:0000800)
0.0	0.1	GO:0008282	ATP-sensitive potassium channel complex(GO:0008282)
0.0	0.3	GO:0005885	Arp2/3 protein complex(GO:0005885)
0.0	0.1	GO:0035189	Rb-E2F complex(GO:0035189)
0.0	0.2	GO:0033256	I-kappaB/NF-kappaB complex(GO:0033256)
0.0	0.1	GO:0035098	ESC/E(Z) complex(GO:0035098)
0.0	0.1	GO:0070937	CRD-mediated mRNA stability complex(GO:0070937)
0.0	0.3	GO:0031463	Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0	0.3	GO:0042101	T cell receptor complex(GO:0042101)
0.0	1.3	GO:0000118	histone deacetylase complex(GO:0000118)
0.0	0.2	GO:0000407	pre-autophagosomal structure(GO:0000407) pre-autophagosomal structure membrane(GO:0034045)
0.0	0.3	GO:0008278	cohesin complex(GO:0008278)
0.0	0.1	GO:0031618	nuclear pericentric heterochromatin(GO:0031618)
0.0	0.1	GO:0033553	rDNA heterochromatin(GO:0033553)
0.0	0.1	GO:0031371	ubiquitin conjugating enzyme complex(GO:0031371)
0.0	0.1	GO:0031088	platelet dense granule membrane(GO:0031088)
0.0	0.1	GO:0002141	stereocilia coupling link(GO:0002139) stereocilia ankle link(GO:0002141) stereocilia ankle link complex(GO:0002142)
0.0	0.1	GO:0045275	mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
0.0	0.1	GO:0048179	activin receptor complex(GO:0048179)
0.0	0.1	GO:0070552	BRISC complex(GO:0070552)
0.0	0.1	GO:0042629	mast cell granule(GO:0042629)
0.0	0.1	GO:0005749	mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)(GO:0005749) succinate dehydrogenase complex (ubiquinone)(GO:0045257) respiratory chain complex II(GO:0045273) succinate dehydrogenase complex(GO:0045281) fumarate reductase complex(GO:0045283)
0.0	0.0	GO:0031932	TORC2 complex(GO:0031932)
0.0	0.3	GO:0005942	phosphatidylinositol 3-kinase complex(GO:0005942)
0.0	0.1	GO:0032593	insulin-responsive compartment(GO:0032593)
0.0	0.3	GO:0016514	SWI/SNF complex(GO:0016514)
0.0	0.1	GO:0030891	VCB complex(GO:0030891)
0.0	0.1	GO:0044224	juxtaparanode region of axon(GO:0044224)
0.0	0.2	GO:0042555	MCM complex(GO:0042555)
0.0	0.7	GO:0005626	obsolete insoluble fraction(GO:0005626)
0.0	0.1	GO:0030895	apolipoprotein B mRNA editing enzyme complex(GO:0030895)
0.0	0.1	GO:0043218	compact myelin(GO:0043218)
0.0	0.1	GO:0032588	trans-Golgi network membrane(GO:0032588)
0.0	0.3	GO:0030132	clathrin coat of coated pit(GO:0030132)
0.0	0.3	GO:0030530	obsolete heterogeneous nuclear ribonucleoprotein complex(GO:0030530)
0.0	0.2	GO:0031258	lamellipodium membrane(GO:0031258)
0.0	0.1	GO:0070695	FHF complex(GO:0070695)
0.0	0.1	GO:0000124	SAGA complex(GO:0000124)
0.0	0.1	GO:0002080	acrosomal membrane(GO:0002080)
0.0	0.3	GO:0005720	nuclear heterochromatin(GO:0005720)
0.0	0.2	GO:0031080	nuclear pore outer ring(GO:0031080)
0.0	0.0	GO:0060199	clathrin-sculpted glutamate transport vesicle(GO:0060199) clathrin-sculpted glutamate transport vesicle membrane(GO:0060203)
0.0	0.1	GO:0005638	lamin filament(GO:0005638)
0.0	0.1	GO:0031262	Ndc80 complex(GO:0031262)
0.0	0.1	GO:0005697	telomerase holoenzyme complex(GO:0005697)
0.0	0.1	GO:0005682	U5 snRNP(GO:0005682)
0.0	0.1	GO:0070776	H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.0	0.1	GO:0005742	mitochondrial outer membrane translocase complex(GO:0005742)
0.0	0.1	GO:0070531	BRCA1-A complex(GO:0070531)
0.0	0.4	GO:0005844	polysome(GO:0005844)
0.0	0.2	GO:0043209	myelin sheath(GO:0043209)
0.0	0.1	GO:0042382	paraspeckles(GO:0042382)
0.0	0.2	GO:0008250	oligosaccharyltransferase complex(GO:0008250)
0.0	0.1	GO:0030992	intraciliary transport particle B(GO:0030992)
0.0	0.2	GO:0001673	male germ cell nucleus(GO:0001673)
0.0	0.5	GO:0030175	filopodium(GO:0030175)
0.0	0.4	GO:0030118	clathrin coat(GO:0030118)
0.0	0.1	GO:0016461	unconventional myosin complex(GO:0016461)
0.0	0.4	GO:0005689	U12-type spliceosomal complex(GO:0005689)
0.0	0.1	GO:0070761	pre-snoRNP complex(GO:0070761)
0.0	0.1	GO:0042584	chromaffin granule(GO:0042583) chromaffin granule membrane(GO:0042584)
0.0	0.7	GO:0000790	nuclear chromatin(GO:0000790)
0.0	0.6	GO:0022625	cytosolic large ribosomal subunit(GO:0022625)
0.0	0.3	GO:0000159	protein phosphatase type 2A complex(GO:0000159)
0.0	0.0	GO:0005850	eukaryotic translation initiation factor 2 complex(GO:0005850)
0.0	0.1	GO:0014701	junctional sarcoplasmic reticulum membrane(GO:0014701)
0.0	0.2	GO:0035631	CD40 receptor complex(GO:0035631)
0.0	0.2	GO:0031941	filamentous actin(GO:0031941)
0.0	0.1	GO:0045334	clathrin-coated endocytic vesicle(GO:0045334)
0.0	0.4	GO:0005876	spindle microtubule(GO:0005876)
0.0	0.3	GO:0000932	cytoplasmic mRNA processing body(GO:0000932)
0.0	0.1	GO:0000276	mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.0	0.2	GO:0005779	integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231)
0.0	0.0	GO:0008540	proteasome regulatory particle, base subcomplex(GO:0008540)
0.0	0.0	GO:0070062	extracellular exosome(GO:0070062) extracellular vesicle(GO:1903561)
0.0	0.5	GO:0016592	mediator complex(GO:0016592)
0.0	0.1	GO:0034362	low-density lipoprotein particle(GO:0034362)
0.0	0.0	GO:0030934	anchoring collagen complex(GO:0030934)
0.0	0.1	GO:0001772	immunological synapse(GO:0001772)
0.0	0.3	GO:0031201	SNARE complex(GO:0031201)
0.0	0.0	GO:0038201	TOR complex(GO:0038201)
0.0	1.1	GO:0008076	voltage-gated potassium channel complex(GO:0008076) potassium channel complex(GO:0034705)
0.0	0.0	GO:0032444	activin responsive factor complex(GO:0032444)
0.0	0.1	GO:0097525	spliceosomal snRNP complex(GO:0097525)
0.0	0.2	GO:0071203	WASH complex(GO:0071203)
0.0	0.1	GO:0042587	glycogen granule(GO:0042587)
0.0	0.3	GO:0044665	MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339)
0.0	0.1	GO:0030061	mitochondrial crista(GO:0030061)
0.0	0.0	GO:0034363	intermediate-density lipoprotein particle(GO:0034363)
0.0	0.1	GO:0005954	calcium- and calmodulin-dependent protein kinase complex(GO:0005954)
0.0	0.1	GO:0032839	dendrite cytoplasm(GO:0032839)
0.0	0.1	GO:0030126	COPI vesicle coat(GO:0030126)
0.0	0.1	GO:0045120	pronucleus(GO:0045120)
0.0	0.5	GO:0005747	mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0	0.0	GO:0042827	platelet dense granule(GO:0042827)
0.0	0.0	GO:0031205	endoplasmic reticulum Sec complex(GO:0031205)
0.0	0.4	GO:0000781	chromosome, telomeric region(GO:0000781)
0.0	0.1	GO:0000125	PCAF complex(GO:0000125)
0.0	0.0	GO:0017071	intracellular cyclic nucleotide activated cation channel complex(GO:0017071)
0.0	0.2	GO:0032420	stereocilium(GO:0032420)
0.0	0.1	GO:0042719	mitochondrial intermembrane space protein transporter complex(GO:0042719)
0.0	0.0	GO:0005594	collagen type IX trimer(GO:0005594)
0.0	0.0	GO:0030137	COPI-coated vesicle(GO:0030137)
0.0	0.0	GO:0032059	bleb(GO:0032059)
0.0	0.3	GO:0031907	peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.0	0.0	GO:0016600	flotillin complex(GO:0016600)
0.0	0.1	GO:0061202	clathrin-sculpted gamma-aminobutyric acid transport vesicle(GO:0061200) clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane(GO:0061202)
0.0	0.1	GO:0034464	BBSome(GO:0034464)
0.0	0.1	GO:0019907	cyclin-dependent protein kinase activating kinase holoenzyme complex(GO:0019907)
0.0	0.2	GO:0005763	organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.0	0.0	GO:0008537	proteasome activator complex(GO:0008537)
0.0	0.1	GO:0005678	obsolete chromatin assembly complex(GO:0005678)
0.0	0.1	GO:0031528	microvillus membrane(GO:0031528)
0.0	0.3	GO:0043204	perikaryon(GO:0043204)
0.0	0.2	GO:0045335	phagocytic vesicle(GO:0045335)
0.0	0.0	GO:0070852	cell body fiber(GO:0070852)
0.0	0.2	GO:0016460	myosin II complex(GO:0016460)
0.0	0.1	GO:0005852	eukaryotic translation initiation factor 3 complex(GO:0005852)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	0.5	GO:0008454	alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.1	0.4	GO:0034236	protein kinase A catalytic subunit binding(GO:0034236)
0.1	0.4	GO:0035184	histone threonine kinase activity(GO:0035184)
0.1	0.4	GO:0016286	small conductance calcium-activated potassium channel activity(GO:0016286)
0.1	0.3	GO:0004719	protein-L-isoaspartate (D-aspartate) O-methyltransferase activity(GO:0004719)
0.1	0.3	GO:0042608	T cell receptor binding(GO:0042608)
0.1	0.3	GO:0004911	interleukin-2 receptor activity(GO:0004911)
0.1	0.6	GO:0016494	C-X-C chemokine receptor activity(GO:0016494)
0.1	0.3	GO:0008321	Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.1	0.3	GO:0016312	inositol bisphosphate phosphatase activity(GO:0016312)
0.1	0.2	GO:0016842	amidine-lyase activity(GO:0016842)
0.1	0.4	GO:0031434	mitogen-activated protein kinase kinase binding(GO:0031434)
0.1	0.2	GO:0008107	galactoside 2-alpha-L-fucosyltransferase activity(GO:0008107) alpha-(1,2)-fucosyltransferase activity(GO:0031127)
0.1	0.3	GO:0008853	exodeoxyribonuclease III activity(GO:0008853)
0.1	0.3	GO:0036002	pre-mRNA binding(GO:0036002)
0.1	0.2	GO:0008192	RNA guanylyltransferase activity(GO:0008192)
0.1	0.3	GO:0070700	BMP receptor binding(GO:0070700)
0.1	0.2	GO:0030284	estrogen receptor activity(GO:0030284)
0.1	0.2	GO:0000400	four-way junction DNA binding(GO:0000400)
0.1	0.2	GO:0016309	1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
0.1	0.8	GO:0005095	GTPase inhibitor activity(GO:0005095)
0.1	0.7	GO:0004697	protein kinase C activity(GO:0004697)
0.1	0.3	GO:0008266	poly(U) RNA binding(GO:0008266)
0.1	0.7	GO:0030159	receptor signaling complex scaffold activity(GO:0030159)
0.1	0.3	GO:0034452	dynactin binding(GO:0034452)
0.1	0.2	GO:0047756	chondroitin 4-sulfotransferase activity(GO:0047756)
0.1	0.3	GO:0005007	fibroblast growth factor-activated receptor activity(GO:0005007)
0.1	0.2	GO:0055103	ligase regulator activity(GO:0055103) ubiquitin-protein transferase regulator activity(GO:0055106)
0.1	0.5	GO:0034593	phosphatidylinositol bisphosphate phosphatase activity(GO:0034593)
0.1	0.4	GO:0061659	ubiquitin-ubiquitin ligase activity(GO:0034450) ubiquitin protein ligase activity(GO:0061630) ubiquitin-like protein ligase activity(GO:0061659)
0.1	0.3	GO:0035259	glucocorticoid receptor binding(GO:0035259)
0.1	0.1	GO:0016362	activin receptor activity, type II(GO:0016362)
0.1	0.2	GO:0005025	transforming growth factor beta receptor activity, type I(GO:0005025)
0.1	0.2	GO:0046975	histone methyltransferase activity (H3-K36 specific)(GO:0046975)
0.0	0.4	GO:0043425	bHLH transcription factor binding(GO:0043425)
0.0	0.3	GO:0031491	nucleosome binding(GO:0031491)
0.0	0.1	GO:0070644	vitamin D response element binding(GO:0070644)
0.0	0.2	GO:0051864	histone demethylase activity (H3-K36 specific)(GO:0051864)
0.0	0.2	GO:0004865	protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.0	0.1	GO:0035005	1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.0	0.1	GO:0043398	HLH domain binding(GO:0043398)
0.0	0.1	GO:0003701	obsolete RNA polymerase I transcription factor activity(GO:0003701)
0.0	0.1	GO:0008331	high voltage-gated calcium channel activity(GO:0008331)
0.0	0.1	GO:0046935	1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.0	0.2	GO:0003960	NADPH:quinone reductase activity(GO:0003960)
0.0	0.1	GO:0005113	patched binding(GO:0005113)
0.0	0.2	GO:0070273	phosphatidylinositol-4-phosphate binding(GO:0070273)
0.0	0.1	GO:0033691	sialic acid binding(GO:0033691)
0.0	0.3	GO:0004691	cAMP-dependent protein kinase activity(GO:0004691)
0.0	0.1	GO:0008174	mRNA methyltransferase activity(GO:0008174)
0.0	0.2	GO:0051766	inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440) inositol trisphosphate kinase activity(GO:0051766)
0.0	0.2	GO:0005384	manganese ion transmembrane transporter activity(GO:0005384)
0.0	0.1	GO:0019911	structural constituent of myelin sheath(GO:0019911)
0.0	0.2	GO:0004448	isocitrate dehydrogenase activity(GO:0004448)
0.0	0.1	GO:0004045	aminoacyl-tRNA hydrolase activity(GO:0004045)
0.0	0.2	GO:0016723	oxidoreductase activity, oxidizing metal ions, NAD or NADP as acceptor(GO:0016723)
0.0	0.2	GO:0030020	extracellular matrix structural constituent conferring tensile strength(GO:0030020)
0.0	0.2	GO:0004028	3-chloroallyl aldehyde dehydrogenase activity(GO:0004028)
0.0	0.0	GO:0032137	guanine/thymine mispair binding(GO:0032137)
0.0	0.3	GO:0003785	actin monomer binding(GO:0003785)
0.0	0.6	GO:0005086	ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0	0.2	GO:0000832	inositol hexakisphosphate kinase activity(GO:0000828) inositol hexakisphosphate 5-kinase activity(GO:0000832)
0.0	0.1	GO:0043008	ATP-dependent protein binding(GO:0043008)
0.0	0.1	GO:0031628	opioid receptor binding(GO:0031628)
0.0	0.3	GO:0016493	C-C chemokine receptor activity(GO:0016493)
0.0	0.5	GO:0019534	toxin transporter activity(GO:0019534)
0.0	0.1	GO:0008109	N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109)
0.0	0.3	GO:0003711	obsolete transcription elongation regulator activity(GO:0003711)
0.0	0.2	GO:0004969	histamine receptor activity(GO:0004969)
0.0	0.1	GO:0005250	A-type (transient outward) potassium channel activity(GO:0005250)
0.0	0.1	GO:0015204	urea transmembrane transporter activity(GO:0015204)
0.0	0.1	GO:0005131	growth hormone receptor binding(GO:0005131)
0.0	0.2	GO:0030332	cyclin binding(GO:0030332)
0.0	0.1	GO:0034237	protein kinase A regulatory subunit binding(GO:0034237)
0.0	0.1	GO:0004814	arginine-tRNA ligase activity(GO:0004814)
0.0	0.1	GO:0003953	NAD+ nucleosidase activity(GO:0003953)
0.0	0.2	GO:0043422	protein kinase B binding(GO:0043422)
0.0	0.1	GO:0030306	ADP-ribosylation factor binding(GO:0030306)
0.0	0.1	GO:0005275	amine transmembrane transporter activity(GO:0005275)
0.0	0.3	GO:0004385	guanylate kinase activity(GO:0004385)
0.0	0.2	GO:0004703	G-protein coupled receptor kinase activity(GO:0004703)
0.0	0.3	GO:0043395	heparan sulfate proteoglycan binding(GO:0043395)
0.0	0.1	GO:0005111	type 2 fibroblast growth factor receptor binding(GO:0005111)
0.0	0.2	GO:0070569	uridylyltransferase activity(GO:0070569)
0.0	0.2	GO:0004861	cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.0	0.2	GO:0005068	transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.0	0.1	GO:0048039	ubiquinone binding(GO:0048039)
0.0	0.2	GO:0031996	thioesterase binding(GO:0031996)
0.0	0.1	GO:0005381	iron ion transmembrane transporter activity(GO:0005381)
0.0	0.1	GO:0003691	double-stranded telomeric DNA binding(GO:0003691)
0.0	0.2	GO:0004726	non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.0	0.1	GO:0042392	sphingosine-1-phosphate phosphatase activity(GO:0042392)
0.0	0.1	GO:0015038	glutathione disulfide oxidoreductase activity(GO:0015038)
0.0	0.4	GO:0043014	alpha-tubulin binding(GO:0043014)
0.0	0.1	GO:0004985	opioid receptor activity(GO:0004985)
0.0	0.1	GO:0004311	farnesyltranstransferase activity(GO:0004311)
0.0	0.2	GO:0070577	lysine-acetylated histone binding(GO:0070577)
0.0	0.1	GO:0055077	gap junction hemi-channel activity(GO:0055077)
0.0	0.1	GO:0036137	kynurenine-oxoglutarate transaminase activity(GO:0016212) kynurenine aminotransferase activity(GO:0036137)
0.0	0.1	GO:0004904	interferon receptor activity(GO:0004904)
0.0	0.6	GO:0003950	NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.0	0.4	GO:0051059	NF-kappaB binding(GO:0051059)
0.0	0.1	GO:0008486	diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486)
0.0	0.1	GO:0005176	ErbB-2 class receptor binding(GO:0005176)
0.0	0.1	GO:0008510	sodium:bicarbonate symporter activity(GO:0008510)
0.0	0.1	GO:0002162	dystroglycan binding(GO:0002162)
0.0	0.1	GO:0004999	vasoactive intestinal polypeptide receptor activity(GO:0004999)
0.0	0.1	GO:0043533	inositol 1,3,4,5 tetrakisphosphate binding(GO:0043533)
0.0	0.1	GO:0031435	mitogen-activated protein kinase kinase kinase binding(GO:0031435)
0.0	0.1	GO:0070513	death domain binding(GO:0070513)
0.0	0.2	GO:0043325	phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.0	0.2	GO:0030507	spectrin binding(GO:0030507)
0.0	0.4	GO:0005484	SNAP receptor activity(GO:0005484)
0.0	0.1	GO:0033300	dehydroascorbic acid transporter activity(GO:0033300)
0.0	0.2	GO:0008139	nuclear localization sequence binding(GO:0008139)
0.0	0.1	GO:0004815	aspartate-tRNA ligase activity(GO:0004815)
0.0	0.2	GO:0004579	dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.0	0.0	GO:0000268	peroxisome targeting sequence binding(GO:0000268)
0.0	0.2	GO:0051721	protein phosphatase 2A binding(GO:0051721)
0.0	0.1	GO:0004505	phenylalanine 4-monooxygenase activity(GO:0004505)
0.0	0.5	GO:0019212	phosphatase inhibitor activity(GO:0019212)
0.0	0.8	GO:0004715	non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.0	0.3	GO:0043027	cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.0	0.1	GO:0000739	obsolete DNA strand annealing activity(GO:0000739)
0.0	0.2	GO:0001671	ATPase activator activity(GO:0001671)
0.0	0.0	GO:0015440	oligopeptide-transporting ATPase activity(GO:0015421) peptide-transporting ATPase activity(GO:0015440)
0.0	0.1	GO:0008526	phosphatidylinositol transporter activity(GO:0008526)
0.0	0.1	GO:0005315	inorganic phosphate transmembrane transporter activity(GO:0005315)
0.0	0.1	GO:0050733	RS domain binding(GO:0050733)
0.0	0.2	GO:0046969	NAD-dependent histone deacetylase activity(GO:0017136) histone deacetylase activity (H3-K9 specific)(GO:0032129) NAD-dependent histone deacetylase activity (H3-K9 specific)(GO:0046969)
0.0	0.2	GO:0004017	adenylate kinase activity(GO:0004017)
0.0	0.1	GO:0080025	phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.0	0.1	GO:0003886	DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.0	0.1	GO:0042288	MHC class I protein binding(GO:0042288)
0.0	0.1	GO:0051019	mitogen-activated protein kinase binding(GO:0051019)
0.0	0.2	GO:0003857	3-hydroxyacyl-CoA dehydrogenase activity(GO:0003857)
0.0	0.5	GO:0001104	RNA polymerase II transcription cofactor activity(GO:0001104)
0.0	0.3	GO:0005164	tumor necrosis factor receptor binding(GO:0005164)
0.0	0.1	GO:0015252	hydrogen ion channel activity(GO:0015252)
0.0	0.1	GO:0004169	dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.0	0.1	GO:0030506	ankyrin binding(GO:0030506)
0.0	0.1	GO:0030515	snoRNA binding(GO:0030515)
0.0	0.1	GO:0001784	phosphotyrosine binding(GO:0001784)
0.0	0.0	GO:0000404	heteroduplex DNA loop binding(GO:0000404)
0.0	0.3	GO:0019198	transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.0	0.3	GO:0003730	mRNA 3'-UTR binding(GO:0003730)
0.0	0.1	GO:0050693	LBD domain binding(GO:0050693)
0.0	0.1	GO:0050698	proteoglycan sulfotransferase activity(GO:0050698)
0.0	0.1	GO:0008296	3'-5'-exodeoxyribonuclease activity(GO:0008296)
0.0	0.1	GO:0045569	TRAIL binding(GO:0045569)
0.0	0.1	GO:0001727	lipid kinase activity(GO:0001727)
0.0	0.2	GO:0031593	polyubiquitin binding(GO:0031593)
0.0	0.1	GO:0034416	bisphosphoglycerate phosphatase activity(GO:0034416)
0.0	0.1	GO:0004957	prostaglandin E receptor activity(GO:0004957)
0.0	0.1	GO:0004428	obsolete inositol or phosphatidylinositol kinase activity(GO:0004428)
0.0	0.1	GO:0004563	beta-N-acetylhexosaminidase activity(GO:0004563)
0.0	0.0	GO:0008241	peptidyl-dipeptidase activity(GO:0008241)
0.0	0.2	GO:0017017	MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.0	0.1	GO:0051400	BH domain binding(GO:0051400)
0.0	0.1	GO:0051635	obsolete bacterial cell surface binding(GO:0051635)
0.0	0.0	GO:0031685	adenosine receptor binding(GO:0031685)
0.0	0.2	GO:0043621	protein self-association(GO:0043621)
0.0	0.4	GO:0097472	cyclin-dependent protein serine/threonine kinase activity(GO:0004693) cyclin-dependent protein kinase activity(GO:0097472)
0.0	0.2	GO:0004602	glutathione peroxidase activity(GO:0004602)
0.0	0.0	GO:0032454	histone demethylase activity (H3-K9 specific)(GO:0032454)
0.0	0.0	GO:0004949	cannabinoid receptor activity(GO:0004949)
0.0	0.2	GO:0008601	protein phosphatase type 2A regulator activity(GO:0008601)
0.0	0.1	GO:0008508	bile acid:sodium symporter activity(GO:0008508)
0.0	0.2	GO:0015924	mannosyl-oligosaccharide mannosidase activity(GO:0015924)
0.0	0.1	GO:0017025	TBP-class protein binding(GO:0017025)
0.0	0.0	GO:0004784	superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
0.0	0.4	GO:0016831	carboxy-lyase activity(GO:0016831)
0.0	0.0	GO:0050897	cobalt ion binding(GO:0050897)
0.0	0.1	GO:0016832	aldehyde-lyase activity(GO:0016832)
0.0	0.2	GO:0004016	adenylate cyclase activity(GO:0004016)
0.0	0.1	GO:0070567	cytidylyltransferase activity(GO:0070567)
0.0	0.0	GO:0004775	succinate-CoA ligase (ADP-forming) activity(GO:0004775)
0.0	0.0	GO:0070548	L-glutamine aminotransferase activity(GO:0070548)
0.0	0.1	GO:0004652	polynucleotide adenylyltransferase activity(GO:0004652)
0.0	0.2	GO:0005487	nucleocytoplasmic transporter activity(GO:0005487)
0.0	0.1	GO:0005375	copper ion transmembrane transporter activity(GO:0005375)
0.0	0.5	GO:0004843	thiol-dependent ubiquitin-specific protease activity(GO:0004843) thiol-dependent ubiquitinyl hydrolase activity(GO:0036459) ubiquitinyl hydrolase activity(GO:0101005)
0.0	0.1	GO:0004308	exo-alpha-sialidase activity(GO:0004308) alpha-sialidase activity(GO:0016997)
0.0	0.1	GO:0004143	diacylglycerol kinase activity(GO:0004143)
0.0	0.1	GO:0030331	estrogen receptor binding(GO:0030331)
0.0	0.1	GO:0050700	CARD domain binding(GO:0050700)
0.0	0.3	GO:0050699	WW domain binding(GO:0050699)
0.0	0.1	GO:0042605	peptide antigen binding(GO:0042605)
0.0	0.2	GO:0002039	p53 binding(GO:0002039)
0.0	0.1	GO:0016308	1-phosphatidylinositol-4-phosphate 5-kinase activity(GO:0016308)
0.0	0.1	GO:0003720	telomerase activity(GO:0003720) RNA-directed DNA polymerase activity(GO:0003964)
0.0	0.0	GO:0098599	palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.0	0.1	GO:0004849	uridine kinase activity(GO:0004849)
0.0	0.1	GO:0046974	histone methyltransferase activity (H3-K9 specific)(GO:0046974)
0.0	0.1	GO:0015385	sodium:proton antiporter activity(GO:0015385)
0.0	0.1	GO:0008159	obsolete positive transcription elongation factor activity(GO:0008159)
0.0	0.3	GO:0003823	antigen binding(GO:0003823)
0.0	0.1	GO:0030544	Hsp70 protein binding(GO:0030544)
0.0	0.1	GO:0060590	ATPase regulator activity(GO:0060590)
0.0	0.1	GO:0008195	phosphatidate phosphatase activity(GO:0008195)
0.0	0.0	GO:0043141	ATP-dependent 5'-3' DNA helicase activity(GO:0043141)
0.0	0.0	GO:0019958	C-X-C chemokine binding(GO:0019958) interleukin-8 binding(GO:0019959)
0.0	0.0	GO:0004677	DNA-dependent protein kinase activity(GO:0004677)
0.0	0.1	GO:0017070	U6 snRNA binding(GO:0017070)
0.0	0.5	GO:0008137	NADH dehydrogenase activity(GO:0003954) NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0	0.0	GO:0005042	netrin receptor activity(GO:0005042)
0.0	0.0	GO:0045545	syndecan binding(GO:0045545)
0.0	0.0	GO:0030292	protein tyrosine kinase inhibitor activity(GO:0030292)
0.0	0.1	GO:0015379	potassium:chloride symporter activity(GO:0015379)
0.0	0.0	GO:0070061	fructose binding(GO:0070061)
0.0	0.0	GO:0000403	Y-form DNA binding(GO:0000403)
0.0	0.0	GO:0047631	ADP-ribose diphosphatase activity(GO:0047631)
0.0	0.0	GO:0003896	DNA primase activity(GO:0003896)
0.0	0.0	GO:0008545	JUN kinase kinase activity(GO:0008545)
0.0	0.0	GO:0060230	lipoprotein lipase activator activity(GO:0060230)
0.0	0.6	GO:0008301	DNA binding, bending(GO:0008301)
0.0	0.1	GO:0044390	ubiquitin conjugating enzyme binding(GO:0031624) ubiquitin-like protein conjugating enzyme binding(GO:0044390)
0.0	0.0	GO:0000064	L-ornithine transmembrane transporter activity(GO:0000064)
0.0	0.1	GO:0030976	thiamine pyrophosphate binding(GO:0030976)
0.0	0.0	GO:0019166	trans-2-enoyl-CoA reductase (NADPH) activity(GO:0019166)
0.0	0.0	GO:0015272	ATP-activated inward rectifier potassium channel activity(GO:0015272)
0.0	0.0	GO:0008353	RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.0	0.7	GO:0047485	protein N-terminus binding(GO:0047485)
0.0	0.1	GO:0004075	biotin carboxylase activity(GO:0004075)
0.0	0.1	GO:0042800	histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.0	0.0	GO:0008821	crossover junction endodeoxyribonuclease activity(GO:0008821)
0.0	0.3	GO:0030145	manganese ion binding(GO:0030145)
0.0	0.1	GO:0030276	clathrin binding(GO:0030276)
0.0	0.0	GO:0032266	phosphatidylinositol-3-phosphate binding(GO:0032266)
0.0	0.1	GO:0001848	complement binding(GO:0001848)
0.0	0.1	GO:0005547	phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.0	0.0	GO:0035014	phosphatidylinositol 3-kinase regulator activity(GO:0035014)
0.0	0.0	GO:0035514	DNA demethylase activity(GO:0035514) DNA-N1-methyladenine dioxygenase activity(GO:0043734)
0.0	0.0	GO:0034595	phosphatidylinositol phosphate 5-phosphatase activity(GO:0034595)
0.0	0.0	GO:0003836	beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.0	0.2	GO:0004190	aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001)
0.0	0.3	GO:0051287	NAD binding(GO:0051287)
0.0	0.2	GO:0035064	methylated histone binding(GO:0035064)
0.0	0.3	GO:0003725	double-stranded RNA binding(GO:0003725)
0.0	0.1	GO:0017176	phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.0	0.1	GO:0015165	pyrimidine nucleotide-sugar transmembrane transporter activity(GO:0015165)
0.0	0.1	GO:0016681	ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors(GO:0016679) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.0	0.0	GO:0044620	ACP phosphopantetheine attachment site binding involved in fatty acid biosynthetic process(GO:0000036) ACP phosphopantetheine attachment site binding(GO:0044620) prosthetic group binding(GO:0051192)
0.0	0.0	GO:0043024	ribosomal small subunit binding(GO:0043024)
0.0	0.2	GO:0004003	ATP-dependent DNA helicase activity(GO:0004003)
0.0	0.1	GO:0008553	hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.0	0.1	GO:0000030	mannosyltransferase activity(GO:0000030)
0.0	0.1	GO:0016888	endodeoxyribonuclease activity, producing 5'-phosphomonoesters(GO:0016888)
0.0	0.0	GO:0052866	phosphatidylinositol phosphate phosphatase activity(GO:0052866)
0.0	0.2	GO:0001608	G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.0	0.0	GO:0004052	arachidonate 12-lipoxygenase activity(GO:0004052)
0.0	0.0	GO:0016165	linoleate 13S-lipoxygenase activity(GO:0016165)
0.0	0.1	GO:0016175	superoxide-generating NADPH oxidase activity(GO:0016175)
0.0	0.0	GO:0048156	tau protein binding(GO:0048156)
0.0	0.0	GO:0070996	type 1 melanocortin receptor binding(GO:0070996)
0.0	0.1	GO:0017040	ceramidase activity(GO:0017040)
0.0	0.1	GO:0030275	LRR domain binding(GO:0030275)
0.0	0.1	GO:0005251	delayed rectifier potassium channel activity(GO:0005251)
0.0	0.1	GO:0004176	ATP-dependent peptidase activity(GO:0004176)
0.0	0.0	GO:0034186	apolipoprotein A-I binding(GO:0034186)
0.0	0.1	GO:0016406	carnitine O-acyltransferase activity(GO:0016406)
0.0	0.1	GO:0046625	sphingolipid binding(GO:0046625)
0.0	0.1	GO:0016776	phosphotransferase activity, phosphate group as acceptor(GO:0016776)
0.0	0.1	GO:0001875	lipopolysaccharide receptor activity(GO:0001875)
0.0	0.1	GO:0004467	long-chain fatty acid-CoA ligase activity(GO:0004467)
0.0	0.2	GO:0008484	sulfuric ester hydrolase activity(GO:0008484)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	2.0	PID REELIN PATHWAY	Reelin signaling pathway
0.0	0.6	PID TCR JNK PATHWAY	JNK signaling in the CD4+ TCR pathway
0.0	0.3	ST PAC1 RECEPTOR PATHWAY	PAC1 Receptor Pathway
0.0	0.2	PID BETA CATENIN DEG PATHWAY	Degradation of beta catenin
0.0	0.1	PID IL8 CXCR1 PATHWAY	IL8- and CXCR1-mediated signaling events
0.0	1.8	PID NFAT TFPATHWAY	Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0	2.0	PID TCR PATHWAY	TCR signaling in naïve CD4+ T cells
0.0	0.3	PID P38 GAMMA DELTA PATHWAY	Signaling mediated by p38-gamma and p38-delta
0.0	0.5	PID LPA4 PATHWAY	LPA4-mediated signaling events
0.0	0.1	PID CD8 TCR PATHWAY	TCR signaling in naïve CD8+ T cells
0.0	0.3	SA PTEN PATHWAY	PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.0	0.9	PID HIV NEF PATHWAY	HIV-1 Nef: Negative effector of Fas and TNF-alpha
0.0	0.1	PID IL5 PATHWAY	IL5-mediated signaling events
0.0	1.2	PID LKB1 PATHWAY	LKB1 signaling events
0.0	1.2	PID NFAT 3PATHWAY	Role of Calcineurin-dependent NFAT signaling in lymphocytes
0.0	0.1	PID WNT NONCANONICAL PATHWAY	Noncanonical Wnt signaling pathway
0.0	0.4	SA MMP CYTOKINE CONNECTION	Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0	0.1	ST INTERFERON GAMMA PATHWAY	Interferon gamma pathway.
0.0	0.4	PID EPHRINB REV PATHWAY	Ephrin B reverse signaling
0.0	0.4	PID IL2 STAT5 PATHWAY	IL2 signaling events mediated by STAT5
0.0	0.2	PID TRAIL PATHWAY	TRAIL signaling pathway
0.0	0.1	ST G ALPHA S PATHWAY	G alpha s Pathway
0.0	0.5	PID P38 ALPHA BETA PATHWAY	Regulation of p38-alpha and p38-beta
0.0	0.4	PID SYNDECAN 3 PATHWAY	Syndecan-3-mediated signaling events
0.0	0.6	PID IL8 CXCR2 PATHWAY	IL8- and CXCR2-mediated signaling events
0.0	0.1	SA G2 AND M PHASES	Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.0	0.2	SA CASPASE CASCADE	Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.0	0.1	PID GMCSF PATHWAY	GMCSF-mediated signaling events
0.0	0.3	PID RETINOIC ACID PATHWAY	Retinoic acid receptors-mediated signaling
0.0	0.3	PID IL3 PATHWAY	IL3-mediated signaling events
0.0	0.8	PID AR TF PATHWAY	Regulation of Androgen receptor activity
0.0	0.7	PID PLK1 PATHWAY	PLK1 signaling events
0.0	0.1	PID P38 MK2 PATHWAY	p38 signaling mediated by MAPKAP kinases
0.0	0.4	PID WNT CANONICAL PATHWAY	Canonical Wnt signaling pathway
0.0	0.4	PID PI3KCI PATHWAY	Class I PI3K signaling events
0.0	0.3	PID CERAMIDE PATHWAY	Ceramide signaling pathway
0.0	0.4	PID ERBB1 INTERNALIZATION PATHWAY	Internalization of ErbB1
0.0	0.3	PID ALK1 PATHWAY	ALK1 signaling events
0.0	0.1	ST TYPE I INTERFERON PATHWAY	Type I Interferon (alpha/beta IFN) Pathway
0.0	0.4	PID ATR PATHWAY	ATR signaling pathway
0.0	0.4	PID CDC42 REG PATHWAY	Regulation of CDC42 activity
0.0	0.1	PID KIT PATHWAY	Signaling events mediated by Stem cell factor receptor (c-Kit)
0.0	0.1	PID IL2 1PATHWAY	IL2-mediated signaling events
0.0	0.2	PID MYC PATHWAY	C-MYC pathway
0.0	0.2	PID TXA2PATHWAY	Thromboxane A2 receptor signaling
0.0	0.1	PID ERB GENOMIC PATHWAY	Validated nuclear estrogen receptor beta network
0.0	0.2	PID HIF1A PATHWAY	Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.0	0.7	PID ERBB1 DOWNSTREAM PATHWAY	ErbB1 downstream signaling
0.0	0.1	PID EPO PATHWAY	EPO signaling pathway
0.0	0.5	PID P53 REGULATION PATHWAY	p53 pathway
0.0	0.2	ST WNT CA2 CYCLIC GMP PATHWAY	Wnt/Ca2+/cyclic GMP signaling.
0.0	0.2	PID BCR 5PATHWAY	BCR signaling pathway
0.0	0.2	PID SYNDECAN 2 PATHWAY	Syndecan-2-mediated signaling events
0.0	0.1	SA G1 AND S PHASES	Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition.
0.0	0.1	PID RXR VDR PATHWAY	RXR and RAR heterodimerization with other nuclear receptor
0.0	0.4	PID MTOR 4PATHWAY	mTOR signaling pathway
0.0	0.4	PID RHOA REG PATHWAY	Regulation of RhoA activity
0.0	0.1	PID IL2 PI3K PATHWAY	IL2 signaling events mediated by PI3K
0.0	0.3	PID RB 1PATHWAY	Regulation of retinoblastoma protein
0.0	0.0	PID PI3KCI AKT PATHWAY	Class I PI3K signaling events mediated by Akt
0.0	0.2	PID ATM PATHWAY	ATM pathway
0.0	0.2	PID S1P META PATHWAY	Sphingosine 1-phosphate (S1P) pathway
0.0	0.1	PID AMB2 NEUTROPHILS PATHWAY	amb2 Integrin signaling
0.0	0.0	PID GLYPICAN 1PATHWAY	Glypican 1 network
0.0	0.2	PID INTEGRIN2 PATHWAY	Beta2 integrin cell surface interactions

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.4	REACTOME BINDING AND ENTRY OF HIV VIRION	Genes involved in Binding and entry of HIV virion
0.1	0.2	REACTOME CDC6 ASSOCIATION WITH THE ORC ORIGIN COMPLEX	Genes involved in CDC6 association with the ORC:origin complex
0.1	0.9	REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS	Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.1	1.1	REACTOME NEPHRIN INTERACTIONS	Genes involved in Nephrin interactions
0.1	0.6	REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS	Genes involved in Signal regulatory protein (SIRP) family interactions
0.0	0.2	REACTOME IRAK1 RECRUITS IKK COMPLEX	Genes involved in IRAK1 recruits IKK complex
0.0	0.6	REACTOME P38MAPK EVENTS	Genes involved in p38MAPK events
0.0	0.7	REACTOME DOWNSTREAM TCR SIGNALING	Genes involved in Downstream TCR signaling
0.0	1.1	REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE	Genes involved in Synthesis of PIPs at the plasma membrane
0.0	0.3	REACTOME IL 7 SIGNALING	Genes involved in Interleukin-7 signaling
0.0	0.1	REACTOME NEP NS2 INTERACTS WITH THE CELLULAR EXPORT MACHINERY	Genes involved in NEP/NS2 Interacts with the Cellular Export Machinery
0.0	0.1	REACTOME ACTIVATION OF NF KAPPAB IN B CELLS	Genes involved in Activation of NF-kappaB in B Cells
0.0	0.5	REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS	Genes involved in Trafficking of GluR2-containing AMPA receptors
0.0	0.8	REACTOME EFFECTS OF PIP2 HYDROLYSIS	Genes involved in Effects of PIP2 hydrolysis
0.0	0.6	REACTOME ENERGY DEPENDENT REGULATION OF MTOR BY LKB1 AMPK	Genes involved in Energy dependent regulation of mTOR by LKB1-AMPK
0.0	0.3	REACTOME REGULATION OF IFNG SIGNALING	Genes involved in Regulation of IFNG signaling
0.0	0.2	REACTOME REGULATION OF IFNA SIGNALING	Genes involved in Regulation of IFNA signaling
0.0	0.1	REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION	Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.0	0.4	REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS	Genes involved in Extrinsic Pathway for Apoptosis
0.0	0.6	REACTOME RECYCLING PATHWAY OF L1	Genes involved in Recycling pathway of L1
0.0	0.7	REACTOME KINESINS	Genes involved in Kinesins
0.0	0.4	REACTOME EGFR DOWNREGULATION	Genes involved in EGFR downregulation
0.0	0.0	REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC	Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.0	0.4	REACTOME IL RECEPTOR SHC SIGNALING	Genes involved in Interleukin receptor SHC signaling
0.0	0.3	REACTOME UNWINDING OF DNA	Genes involved in Unwinding of DNA
0.0	0.4	REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS	Genes involved in Proteolytic cleavage of SNARE complex proteins
0.0	0.6	REACTOME BASIGIN INTERACTIONS	Genes involved in Basigin interactions
0.0	0.3	REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS	Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.0	0.1	REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX UPON TLR7 8 OR 9 STIMULATION	Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
0.0	0.7	REACTOME ACTIVATION OF ATR IN RESPONSE TO REPLICATION STRESS	Genes involved in Activation of ATR in response to replication stress
0.0	0.2	REACTOME REGULATORY RNA PATHWAYS	Genes involved in Regulatory RNA pathways
0.0	0.0	REACTOME G ALPHA1213 SIGNALLING EVENTS	Genes involved in G alpha (12/13) signalling events
0.0	0.4	REACTOME N GLYCAN ANTENNAE ELONGATION	Genes involved in N-Glycan antennae elongation
0.0	0.5	REACTOME THE ROLE OF NEF IN HIV1 REPLICATION AND DISEASE PATHOGENESIS	Genes involved in The role of Nef in HIV-1 replication and disease pathogenesis
0.0	0.2	REACTOME IL 3 5 AND GM CSF SIGNALING	Genes involved in Interleukin-3, 5 and GM-CSF signaling
0.0	0.2	REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS	Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.0	0.5	REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA	Genes involved in Circadian Repression of Expression by REV-ERBA
0.0	0.2	REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY	Genes involved in Adenylate cyclase activating pathway
0.0	0.0	REACTOME P53 INDEPENDENT G1 S DNA DAMAGE CHECKPOINT	Genes involved in p53-Independent G1/S DNA damage checkpoint
0.0	0.0	REACTOME S PHASE	Genes involved in S Phase
0.0	0.3	REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY	Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.0	0.0	REACTOME ASSOCIATION OF LICENSING FACTORS WITH THE PRE REPLICATIVE COMPLEX	Genes involved in Association of licensing factors with the pre-replicative complex
0.0	0.0	REACTOME TRANSPORT OF RIBONUCLEOPROTEINS INTO THE HOST NUCLEUS	Genes involved in Transport of Ribonucleoproteins into the Host Nucleus
0.0	0.1	REACTOME N GLYCAN ANTENNAE ELONGATION IN THE MEDIAL TRANS GOLGI	Genes involved in N-glycan antennae elongation in the medial/trans-Golgi
0.0	0.4	REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS	Genes involved in Apoptotic cleavage of cellular proteins
0.0	0.4	REACTOME CTLA4 INHIBITORY SIGNALING	Genes involved in CTLA4 inhibitory signaling
0.0	0.3	REACTOME ELONGATION ARREST AND RECOVERY	Genes involved in Elongation arrest and recovery
0.0	0.4	REACTOME CITRIC ACID CYCLE TCA CYCLE	Genes involved in Citric acid cycle (TCA cycle)
0.0	0.5	REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE	Genes involved in Sema4D induced cell migration and growth-cone collapse
0.0	0.2	REACTOME MRNA CAPPING	Genes involved in mRNA Capping
0.0	0.2	REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION	Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.0	0.0	REACTOME SIGNALING BY ERBB2	Genes involved in Signaling by ERBB2
0.0	0.2	REACTOME COPI MEDIATED TRANSPORT	Genes involved in COPI Mediated Transport
0.0	0.3	REACTOME HDL MEDIATED LIPID TRANSPORT	Genes involved in HDL-mediated lipid transport
0.0	0.2	REACTOME REGULATION OF COMPLEMENT CASCADE	Genes involved in Regulation of Complement cascade
0.0	0.2	REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING	Genes involved in Formation of ATP by chemiosmotic coupling
0.0	0.2	REACTOME RNA POL I TRANSCRIPTION INITIATION	Genes involved in RNA Polymerase I Transcription Initiation
0.0	0.7	REACTOME VOLTAGE GATED POTASSIUM CHANNELS	Genes involved in Voltage gated Potassium channels
0.0	0.1	REACTOME PROSTANOID LIGAND RECEPTORS	Genes involved in Prostanoid ligand receptors
0.0	0.2	REACTOME SIGNALING BY ACTIVATED POINT MUTANTS OF FGFR1	Genes involved in Signaling by activated point mutants of FGFR1
0.0	0.2	REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE	Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.0	0.2	REACTOME NUCLEAR EVENTS KINASE AND TRANSCRIPTION FACTOR ACTIVATION	Genes involved in Nuclear Events (kinase and transcription factor activation)
0.0	0.8	REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL	Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0	0.2	REACTOME GENERATION OF SECOND MESSENGER MOLECULES	Genes involved in Generation of second messenger molecules
0.0	0.3	REACTOME PEROXISOMAL LIPID METABOLISM	Genes involved in Peroxisomal lipid metabolism
0.0	0.6	REACTOME NRAGE SIGNALS DEATH THROUGH JNK	Genes involved in NRAGE signals death through JNK
0.0	0.2	REACTOME TRAF6 MEDIATED NFKB ACTIVATION	Genes involved in TRAF6 mediated NF-kB activation
0.0	0.1	REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION	Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.0	0.0	REACTOME ER PHAGOSOME PATHWAY	Genes involved in ER-Phagosome pathway
0.0	0.1	REACTOME PROLONGED ERK ACTIVATION EVENTS	Genes involved in Prolonged ERK activation events
0.0	0.2	REACTOME SIGNALING BY NOTCH3	Genes involved in Signaling by NOTCH3
0.0	0.2	REACTOME INHIBITION OF THE PROTEOLYTIC ACTIVITY OF APC C REQUIRED FOR THE ONSET OF ANAPHASE BY MITOTIC SPINDLE CHECKPOINT COMPONENTS	Genes involved in Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components
0.0	0.0	REACTOME INTERACTIONS OF VPR WITH HOST CELLULAR PROTEINS	Genes involved in Interactions of Vpr with host cellular proteins
0.0	0.3	REACTOME G1 PHASE	Genes involved in G1 Phase
0.0	0.1	REACTOME PKB MEDIATED EVENTS	Genes involved in PKB-mediated events
0.0	0.2	REACTOME PROCESSING OF INTRONLESS PRE MRNAS	Genes involved in Processing of Intronless Pre-mRNAs
0.0	0.2	REACTOME COSTIMULATION BY THE CD28 FAMILY	Genes involved in Costimulation by the CD28 family
0.0	0.1	REACTOME TRAF3 DEPENDENT IRF ACTIVATION PATHWAY	Genes involved in TRAF3-dependent IRF activation pathway
0.0	1.6	REACTOME PROCESSING OF CAPPED INTRON CONTAINING PRE MRNA	Genes involved in Processing of Capped Intron-Containing Pre-mRNA
0.0	0.3	REACTOME REGULATION OF BETA CELL DEVELOPMENT	Genes involved in Regulation of beta-cell development
0.0	0.8	REACTOME RESPIRATORY ELECTRON TRANSPORT ATP SYNTHESIS BY CHEMIOSMOTIC COUPLING AND HEAT PRODUCTION BY UNCOUPLING PROTEINS	Genes involved in Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins.
0.0	0.0	REACTOME PI3K AKT ACTIVATION	Genes involved in PI3K/AKT activation
0.0	0.1	REACTOME AKT PHOSPHORYLATES TARGETS IN THE CYTOSOL	Genes involved in AKT phosphorylates targets in the cytosol
0.0	0.1	REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS	Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.0	0.1	REACTOME HIGHLY CALCIUM PERMEABLE POSTSYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS	Genes involved in Highly calcium permeable postsynaptic nicotinic acetylcholine receptors
0.0	0.2	REACTOME GLUCAGON SIGNALING IN METABOLIC REGULATION	Genes involved in Glucagon signaling in metabolic regulation
0.0	0.0	REACTOME RNA POL I TRANSCRIPTION	Genes involved in RNA Polymerase I Transcription
0.0	0.2	REACTOME GLUCURONIDATION	Genes involved in Glucuronidation
0.0	0.2	REACTOME DARPP 32 EVENTS	Genes involved in DARPP-32 events
0.0	0.5	REACTOME MITOCHONDRIAL PROTEIN IMPORT	Genes involved in Mitochondrial Protein Import
0.0	0.0	REACTOME ENDOSOMAL VACUOLAR PATHWAY	Genes involved in Endosomal/Vacuolar pathway
0.0	0.7	REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE	Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.0	0.2	REACTOME METAL ION SLC TRANSPORTERS	Genes involved in Metal ion SLC transporters
0.0	0.1	REACTOME NOTCH HLH TRANSCRIPTION PATHWAY	Genes involved in Notch-HLH transcription pathway
0.0	0.9	REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION	Genes involved in Factors involved in megakaryocyte development and platelet production
0.0	0.0	REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING	Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.0	0.0	REACTOME SHC MEDIATED SIGNALLING	Genes involved in SHC-mediated signalling
0.0	0.0	REACTOME FGFR4 LIGAND BINDING AND ACTIVATION	Genes involved in FGFR4 ligand binding and activation
0.0	0.2	REACTOME INTERACTION BETWEEN L1 AND ANKYRINS	Genes involved in Interaction between L1 and Ankyrins
0.0	0.1	REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING	Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.0	0.1	REACTOME UNBLOCKING OF NMDA RECEPTOR GLUTAMATE BINDING AND ACTIVATION	Genes involved in Unblocking of NMDA receptor, glutamate binding and activation

Results for PAX4

Z-value: 2.19

Motif logo

Transcription factors associated with PAX4

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

Activity of the PAX4 motif across conditions

Conditions sorted by the z-value of the PAX4 motif activity

Top target CREs of the motif:

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of PAX4

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category:

Gene overrepresentation in curated gene sets: canonical pathways category:

Gene overrepresentation in curated gene sets: REACTOME pathways category: