Project
ENCODE: H3K4me1 ChIP-Seq of primary human cells
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CREMA is a free online tool that recognizes most important transcription factors that change the chromatin state across different samples.

Results for PBX1

Z-value: 1.36

Motif logo

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Transcription factors associated with PBX1

Gene Symbol Gene ID Gene Info
ENSG00000185630.14 PBX1

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE Gene Distance Association probability Pearson corr. coef. P-value Plot
PBX1chr1_164580979_164581130141890.217248-0.923.6e-04Click!
PBX1chr1_164741025_16474124010170.518282-0.881.7e-03Click!
PBX1chr1_164742488_1647426394140.778690-0.826.9e-03Click!
PBX1chr1_164571766_164571917234020.204453-0.818.0e-03Click!
PBX1chr1_164733455_16473360686190.196572-0.791.2e-02Click!

Activity of the PBX1 motif across conditions

Conditions sorted by the z-value of the PBX1 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE) Target Score Top associated gene Gene Info Distance of CRE to TSS CRE/Gene association probability
chr17_30902769_30903098 0.71 RP11-466A19.5

45866
0.1
chr1_65342372_65342702 0.68 JAK1
Janus kinase 1
89650
0.08
chr3_107695991_107696269 0.64 CD47
CD47 molecule
81078
0.11
chr7_50358033_50358422 0.61 IKZF1
IKAROS family zinc finger 1 (Ikaros)
9018
0.29
chr2_158276348_158276584 0.57 CYTIP
cytohesin 1 interacting protein
19460
0.2
chr6_106737124_106737275 0.56 ENSG00000244710
.
5613
0.2
chr14_98657577_98657728 0.52 ENSG00000222066
.
140435
0.05
chr1_26696466_26696677 0.51 ZNF683
zinc finger protein 683
665
0.58
chr12_69034261_69034415 0.50 ENSG00000206650
.
13183
0.19
chr11_128436850_128437001 0.48 ETS1
v-ets avian erythroblastosis virus E26 oncogene homolog 1
20528
0.21
chr2_99084461_99084735 0.47 INPP4A
inositol polyphosphate-4-phosphatase, type I, 107kDa
23185
0.21
chr17_38763766_38763917 0.46 SMARCE1
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 1
24701
0.13
chr6_159434242_159434587 0.45 RP1-111C20.4

12564
0.17
chr14_91814952_91815599 0.45 ENSG00000265856
.
15218
0.22
chr9_37391017_37391168 0.44 GRHPR
glyoxylate reductase/hydroxypyruvate reductase
31571
0.15
chr10_46053827_46054093 0.44 MARCH8
membrane-associated ring finger (C3HC4) 8, E3 ubiquitin protein ligase
23118
0.22
chr7_37349133_37349657 0.43 ELMO1
engulfment and cell motility 1
32972
0.18
chr9_101789958_101790159 0.43 TGFBR1
transforming growth factor, beta receptor 1
76262
0.09
chr1_169674701_169674897 0.43 SELL
selectin L
6040
0.21
chr1_42793424_42793575 0.43 FOXJ3
forkhead box J3
7137
0.2
chr2_204868825_204868976 0.43 ICOS
inducible T-cell co-stimulator
67397
0.13
chr6_24957255_24957453 0.43 FAM65B
family with sequence similarity 65, member B
21166
0.2
chr2_3246663_3247121 0.42 TSSC1-IT1
TSSC1 intronic transcript 1 (non-protein coding)
58344
0.14
chr21_47972699_47973025 0.42 ENSG00000272283
.
17153
0.17
chr14_89722620_89722771 0.42 FOXN3
forkhead box N3
75607
0.1
chr6_143229651_143229867 0.41 HIVEP2
human immunodeficiency virus type I enhancer binding protein 2
36579
0.2
chr5_151907032_151907224 0.40 NMUR2
neuromedin U receptor 2
122288
0.07
chr21_19148494_19148866 0.40 AL109761.5

17125
0.22
chr5_156999365_156999526 0.40 ADAM19
ADAM metallopeptidase domain 19
3304
0.19
chr7_50306943_50307629 0.39 IKZF1
IKAROS family zinc finger 1 (Ikaros)
37038
0.2
chr2_8625925_8626222 0.39 AC011747.7

189823
0.03
chr9_36145556_36145707 0.39 GLIPR2
GLI pathogenesis-related 2
8889
0.18
chr8_82104288_82104439 0.39 PAG1
phosphoprotein associated with glycosphingolipid microdomains 1
80060
0.09
chr16_57021435_57021712 0.39 NLRC5
NLR family, CARD domain containing 5
1837
0.25
chr14_78224263_78224414 0.39 C14orf178
chromosome 14 open reading frame 178
2835
0.18
chr10_3915023_3915255 0.39 KLF6
Kruppel-like factor 6
87666
0.09
chr2_235204073_235204224 0.39 ARL4C
ADP-ribosylation factor-like 4C
201096
0.03
chr17_40423553_40423822 0.38 AC003104.1

298
0.83
chr16_3623403_3623748 0.38 NLRC3
NLR family, CARD domain containing 3
3817
0.17
chr17_63026003_63026264 0.38 RP11-583F2.5

21894
0.15
chr3_98275754_98275968 0.38 GPR15
G protein-coupled receptor 15
25118
0.13
chr17_66343606_66343891 0.38 ARSG
arylsulfatase G
56089
0.1
chr7_36325933_36326467 0.37 EEPD1
endonuclease/exonuclease/phosphatase family domain containing 1
10553
0.18
chr3_43372779_43372930 0.37 RP11-188P20.3

16281
0.16
chr7_21474691_21474842 0.37 SP4
Sp4 transcription factor
7105
0.2
chr2_148388820_148389572 0.37 ENSG00000253083
.
81927
0.1
chr1_112053499_112053798 0.37 ADORA3
adenosine A3 receptor
7266
0.13
chr8_22967185_22967337 0.37 TNFRSF10C
tumor necrosis factor receptor superfamily, member 10c, decoy without an intracellular domain
6827
0.14
chr19_1935619_1935770 0.36 CSNK1G2
casein kinase 1, gamma 2
5494
0.11
chr9_120588985_120589386 0.36 ENSG00000251847
.
95436
0.08
chr5_7778754_7778905 0.36 RP11-711G10.1

28950
0.2
chr9_100177542_100177693 0.36 TDRD7
tudor domain containing 7
3241
0.29
chr5_55152116_55152357 0.36 IL31RA
interleukin 31 receptor A
2878
0.28
chr18_3059365_3059574 0.36 ENSG00000252258
.
33905
0.13
chr16_46836785_46836936 0.36 C16orf87
chromosome 16 open reading frame 87
28120
0.17
chr5_79486493_79486756 0.36 ENSG00000239159
.
48784
0.12
chr19_18655304_18655455 0.35 FKBP8
FK506 binding protein 8, 38kDa
492
0.6
chr9_92083234_92083501 0.35 SEMA4D
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D
11438
0.23
chr7_114616275_114616426 0.35 MDFIC
MyoD family inhibitor domain containing
42426
0.21
chr19_910573_910814 0.35 R3HDM4
R3H domain containing 4
2538
0.12
chr11_17308544_17308695 0.35 NUCB2
nucleobindin 2
8252
0.21
chr3_71507289_71507548 0.35 ENSG00000221264
.
83822
0.09
chr2_43402102_43402312 0.34 ZFP36L2
ZFP36 ring finger protein-like 2
51541
0.14
chr5_39175400_39175649 0.34 FYB
FYN binding protein
27605
0.22
chr3_33065058_33065320 0.34 CCR4
chemokine (C-C motif) receptor 4
72123
0.08
chr3_186278072_186278223 0.34 TBCCD1
TBCC domain containing 1
3987
0.17
chr4_40231477_40231628 0.34 RHOH
ras homolog family member H
29588
0.18
chr7_21397453_21397701 0.34 ENSG00000195024
.
23404
0.21
chr1_62249924_62250078 0.34 ENSG00000200575
.
32090
0.16
chr10_26752397_26752592 0.34 APBB1IP
amyloid beta (A4) precursor protein-binding, family B, member 1 interacting protein
25140
0.22
chr1_9713515_9713810 0.34 C1orf200
chromosome 1 open reading frame 200
982
0.47
chr6_24894743_24895047 0.34 FAM65B
family with sequence similarity 65, member B
16300
0.2
chr2_99326136_99326596 0.34 MGAT4A
mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme A
16793
0.22
chr1_108446611_108446981 0.34 VAV3-AS1
VAV3 antisense RNA 1
60269
0.13
chr9_31347928_31348079 0.33 ENSG00000211510
.
573777
0.0
chr16_53471043_53471490 0.33 RBL2
retinoblastoma-like 2 (p130)
1735
0.31
chrX_44105289_44105582 0.33 EFHC2
EF-hand domain (C-terminal) containing 2
97483
0.08
chr18_60198457_60198694 0.33 ZCCHC2
zinc finger, CCHC domain containing 2
7723
0.28
chr11_128495468_128495740 0.33 ETS1
v-ets avian erythroblastosis virus E26 oncogene homolog 1
38151
0.15
chr7_76984643_76984884 0.33 GSAP
gamma-secretase activating protein
25079
0.21
chr20_37432775_37433181 0.33 PPP1R16B
protein phosphatase 1, regulatory subunit 16B
1370
0.43
chr2_182128679_182128830 0.33 ENSG00000266705
.
41625
0.21
chr2_145215910_145216141 0.33 ZEB2
zinc finger E-box binding homeobox 2
27888
0.23
chr16_79126975_79127217 0.33 RP11-556H2.3

3149
0.25
chr5_100234402_100234890 0.33 ST8SIA4
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4
4272
0.34
chr19_3136880_3137097 0.33 GNA15
guanine nucleotide binding protein (G protein), alpha 15 (Gq class)
797
0.47
chr14_71464254_71464520 0.33 PCNX
pecanex homolog (Drosophila)
15361
0.29
chr17_33857619_33857982 0.33 SLFN12L
schlafen family member 12-like
7080
0.12
chr20_21527565_21527785 0.33 NKX2-2
NK2 homeobox 2
33011
0.18
chr16_79652368_79652707 0.33 MAF
v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog
17926
0.26
chr9_92109429_92109613 0.33 SEMA4D
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D
2826
0.29
chr17_29700013_29700185 0.32 NF1
neurofibromin 1
14533
0.14
chr9_126630414_126630599 0.32 DENND1A
DENN/MADD domain containing 1A
61880
0.12
chr15_55514570_55514956 0.32 RSL24D1
ribosomal L24 domain containing 1
25498
0.18
chr22_42651907_42652058 0.32 TCF20
transcription factor 20 (AR1)
40534
0.14
chr22_30583521_30583829 0.32 RP3-438O4.4

19423
0.13
chr6_36516425_36516576 0.32 STK38
serine/threonine kinase 38
1253
0.39
chrX_78424933_78425109 0.32 GPR174
G protein-coupled receptor 174
1448
0.59
chr5_75825749_75825973 0.32 IQGAP2
IQ motif containing GTPase activating protein 2
17373
0.24
chr8_117878667_117878892 0.32 RAD21
RAD21 homolog (S. pombe)
7820
0.17
chr17_76766802_76766972 0.32 CYTH1
cytohesin 1
11467
0.18
chr3_71750685_71750964 0.32 EIF4E3
eukaryotic translation initiation factor 4E family member 3
23702
0.2
chr14_91872440_91872844 0.32 CCDC88C
coiled-coil domain containing 88C
11048
0.24
chr8_19331940_19332091 0.32 CSGALNACT1
chondroitin sulfate N-acetylgalactosaminyltransferase 1
127361
0.06
chr3_67729128_67729286 0.31 SUCLG2
succinate-CoA ligase, GDP-forming, beta subunit
24169
0.28
chr12_113527618_113527818 0.31 DTX1
deltex homolog 1 (Drosophila)
32223
0.11
chr1_24840661_24840812 0.31 RCAN3
RCAN family member 3
74
0.97
chr10_105671429_105671739 0.31 OBFC1
oligonucleotide/oligosaccharide-binding fold containing 1
5843
0.19
chrX_135742690_135742856 0.31 CD40LG
CD40 ligand
12387
0.17
chr1_117528994_117529403 0.31 CD101
CD101 molecule
15184
0.16
chr2_12850330_12850505 0.31 TRIB2
tribbles pseudokinase 2
6598
0.28
chr7_127496048_127496199 0.31 SND1
staphylococcal nuclease and tudor domain containing 1
31842
0.22
chr8_67404169_67404359 0.31 C8orf46
chromosome 8 open reading frame 46
1179
0.48
chr20_39775264_39775450 0.31 RP1-1J6.2

8714
0.2
chr3_20147752_20147943 0.31 ENSG00000266745
.
31210
0.16
chr1_101707393_101707553 0.31 RP4-575N6.5

1241
0.4
chr9_71399988_71400193 0.31 FAM122A
family with sequence similarity 122A
5126
0.25
chr1_100847278_100847500 0.31 ENSG00000216067
.
3058
0.27
chr1_40778667_40778833 0.31 COL9A2
collagen, type IX, alpha 2
3612
0.2
chr16_29235615_29235838 0.31 RP11-231C14.6

87945
0.06
chr2_85085633_85085887 0.31 TRABD2A
TraB domain containing 2A
22446
0.18
chr18_29620502_29620880 0.30 ENSG00000265063
.
20261
0.13
chr8_128182820_128182971 0.30 POU5F1B
POU class 5 homeobox 1B
243640
0.02
chr19_30460699_30460945 0.30 URI1
URI1, prefoldin-like chaperone
1178
0.65
chr19_381111_381262 0.30 THEG
theg spermatid protein
5173
0.15
chr11_35147581_35147732 0.30 AL356215.1

2559
0.25
chr1_28582972_28583123 0.30 SESN2
sestrin 2
2991
0.16
chr15_77304869_77305028 0.30 PSTPIP1
proline-serine-threonine phosphatase interacting protein 1
3204
0.26
chrX_48791618_48791902 0.30 PIM2
pim-2 oncogene
15459
0.09
chr1_169558158_169558702 0.30 F5
coagulation factor V (proaccelerin, labile factor)
2604
0.31
chr13_41177729_41177880 0.30 FOXO1
forkhead box O1
62930
0.12
chr10_11183526_11183726 0.30 CELF2
CUGBP, Elav-like family member 2
23367
0.18
chr7_43874382_43874686 0.30 MRPS24
mitochondrial ribosomal protein S24
34622
0.13
chr4_153320237_153320432 0.30 FBXW7
F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase
12696
0.24
chr2_65469172_65469323 0.30 ACTR2
ARP2 actin-related protein 2 homolog (yeast)
14276
0.23
chr1_66805112_66805335 0.30 PDE4B
phosphodiesterase 4B, cAMP-specific
7351
0.32
chr7_21469720_21469989 0.30 SP4
Sp4 transcription factor
2193
0.3
chrX_19804751_19804902 0.30 SH3KBP1
SH3-domain kinase binding protein 1
13043
0.29
chr3_46390356_46390605 0.30 CCR2
chemokine (C-C motif) receptor 2
4745
0.2
chr17_76814852_76815192 0.30 USP36
ubiquitin specific peptidase 36
4309
0.2
chr2_204726088_204726239 0.30 CTLA4
cytotoxic T-lymphocyte-associated protein 4
6346
0.27
chr6_42540871_42541167 0.30 UBR2
ubiquitin protein ligase E3 component n-recognin 2
9219
0.22
chr2_42327539_42327704 0.29 PKDCC
protein kinase domain containing, cytoplasmic
52461
0.13
chr2_143943022_143943284 0.29 RP11-190J23.1

13412
0.27
chr21_36332815_36332966 0.29 RUNX1
runt-related transcription factor 1
70803
0.13
chr12_1813704_1813855 0.29 ADIPOR2
adiponectin receptor 2
13586
0.2
chr7_50350335_50350543 0.29 IKZF1
IKAROS family zinc finger 1 (Ikaros)
2121
0.44
chr18_46927885_46928119 0.29 DYM
dymeclin
22983
0.15
chr6_144740266_144740510 0.29 UTRN
utrophin
75151
0.11
chr17_8800034_8800185 0.29 PIK3R5
phosphoinositide-3-kinase, regulatory subunit 5
14715
0.2
chr10_22963946_22964164 0.29 PIP4K2A
phosphatidylinositol-5-phosphate 4-kinase, type II, alpha
38982
0.2
chr7_1087128_1087349 0.29 GPR146
G protein-coupled receptor 146
3026
0.13
chr2_8615480_8615853 0.29 AC011747.7

200230
0.03
chr2_198670473_198670941 0.29 PLCL1
phospholipase C-like 1
1281
0.51
chr11_18652208_18652359 0.29 SPTY2D1
SPT2, Suppressor of Ty, domain containing 1 (S. cerevisiae)
3757
0.19
chr11_128604204_128604783 0.29 FLI1
Fli-1 proto-oncogene, ETS transcription factor
30192
0.16
chr15_74756022_74756173 0.29 UBL7-AS1
UBL7 antisense RNA 1 (head to head)
2412
0.2
chr11_74986567_74986718 0.29 ARRB1
arrestin, beta 1
3101
0.18
chr10_3709420_3709846 0.29 RP11-184A2.3

83626
0.1
chr2_38898002_38898320 0.29 AC074366.3

402
0.84
chr1_100905257_100905795 0.29 RP5-837M10.4

46027
0.13
chr7_50350560_50351095 0.29 IKZF1
IKAROS family zinc finger 1 (Ikaros)
2509
0.41
chr3_27924725_27925089 0.28 EOMES
eomesodermin
160701
0.04
chr3_195314371_195314522 0.28 APOD
apolipoprotein D
3370
0.23
chr1_100868916_100869067 0.28 ENSG00000216067
.
24660
0.18
chr20_51738395_51738546 0.28 ENSG00000199218
.
24279
0.18
chr3_13055323_13055569 0.28 IQSEC1
IQ motif and Sec7 domain 1
26910
0.23
chr11_121237928_121238130 0.28 SC5D
sterol-C5-desaturase
74468
0.11
chr18_74832353_74832701 0.28 MBP
myelin basic protein
7141
0.31
chr4_89202595_89202746 0.28 PPM1K
protein phosphatase, Mg2+/Mn2+ dependent, 1K
2372
0.23
chr17_38779166_38779543 0.28 SMARCE1
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 1
9188
0.15
chr4_78726984_78727206 0.28 CNOT6L
CCR4-NOT transcription complex, subunit 6-like
13122
0.26
chr2_198071433_198071665 0.28 ANKRD44
ankyrin repeat domain 44
8787
0.21
chr2_225895173_225895367 0.28 DOCK10
dedicator of cytokinesis 10
11889
0.25
chr6_53296483_53296678 0.28 ENSG00000253010
.
16175
0.18
chrX_19762386_19762616 0.28 SH3KBP1
SH3-domain kinase binding protein 1
2028
0.47
chr5_75822469_75822680 0.28 IQGAP2
IQ motif containing GTPase activating protein 2
20660
0.23
chr9_91536946_91537097 0.28 C9orf47
chromosome 9 open reading frame 47
68757
0.11
chr17_30678180_30678332 0.28 ZNF207
zinc finger protein 207
329
0.74
chr5_110652187_110652338 0.28 CTC-499J9.1

13997
0.23
chr3_107781222_107781468 0.28 CD47
CD47 molecule
2966
0.4
chr17_37043988_37044139 0.28 LASP1
LIM and SH3 protein 1
13920
0.09
chr1_54945402_54945553 0.28 ENSG00000265404
.
24864
0.16
chr6_41115741_41115912 0.28 TREML1
triggering receptor expressed on myeloid cells-like 1
6244
0.14
chr17_8858301_8858611 0.28 PIK3R5
phosphoinositide-3-kinase, regulatory subunit 5
10568
0.24
chr18_29623121_29623509 0.28 ENSG00000265063
.
17637
0.13
chr4_38244417_38244568 0.28 ENSG00000221495
.
4258
0.36
chr11_122571839_122572000 0.27 ENSG00000239079
.
25100
0.2
chr10_7554785_7554936 0.27 RP11-385N23.1

20309
0.21
chr2_198081838_198081989 0.27 ANKRD44
ankyrin repeat domain 44
19151
0.19
chr2_136872566_136873100 0.27 CXCR4
chemokine (C-X-C motif) receptor 4
980
0.68
chr22_30712298_30712449 0.27 TBC1D10A
TBC1 domain family, member 10A
8494
0.1
chr8_81955099_81955250 0.27 PAG1
phosphoprotein associated with glycosphingolipid microdomains 1
69129
0.12
chr1_169671553_169671957 0.27 SELL
selectin L
9084
0.2
chr10_87373902_87374053 0.27 RP11-93H12.2

8827
0.23
chr2_204725673_204726054 0.27 CTLA4
cytotoxic T-lymphocyte-associated protein 4
6646
0.27
chr12_68594355_68594506 0.27 IL26
interleukin 26
25171
0.19
chr13_94983282_94983449 0.27 ENSG00000212057
.
134279
0.05
chr17_33861876_33862027 0.27 SLFN12L
schlafen family member 12-like
2929
0.15
chr19_42705324_42705478 0.27 ENSG00000265122
.
8171
0.09

Histogram of CRE-TSS distances for CREs targeted by :

Histogram of

Rank distribution of CRE target scores:

Histogram of target CRE score.

Distribution of target CREs across different genomic regions:

Weighted Piechart of Weighted Piechart of Weighted Piechart of

Network of associatons between targets according to the STRING database.

StringDB image

First level regulatory network of PBX1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.8 GO:0002710 negative regulation of T cell mediated immunity(GO:0002710)
0.2 0.6 GO:0019276 UDP-N-acetylgalactosamine metabolic process(GO:0019276)
0.2 0.8 GO:0030854 positive regulation of granulocyte differentiation(GO:0030854)
0.2 0.8 GO:0033152 immunoglobulin V(D)J recombination(GO:0033152)
0.2 0.2 GO:0002326 B cell lineage commitment(GO:0002326)
0.2 0.7 GO:0046642 negative regulation of alpha-beta T cell proliferation(GO:0046642)
0.2 0.5 GO:0035405 histone-threonine phosphorylation(GO:0035405)
0.2 0.7 GO:0045589 regulation of regulatory T cell differentiation(GO:0045589)
0.2 1.3 GO:0006491 N-glycan processing(GO:0006491)
0.1 0.3 GO:0002664 T cell tolerance induction(GO:0002517) regulation of T cell tolerance induction(GO:0002664) positive regulation of T cell tolerance induction(GO:0002666)
0.1 0.4 GO:0045722 positive regulation of gluconeogenesis(GO:0045722)
0.1 0.4 GO:0070779 D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
0.1 0.5 GO:0032237 activation of store-operated calcium channel activity(GO:0032237) regulation of store-operated calcium channel activity(GO:1901339) positive regulation of store-operated calcium channel activity(GO:1901341)
0.1 0.9 GO:0006198 cAMP catabolic process(GO:0006198)
0.1 0.4 GO:0043320 natural killer cell activation involved in immune response(GO:0002323) natural killer cell degranulation(GO:0043320)
0.1 0.4 GO:0010459 negative regulation of heart rate(GO:0010459)
0.1 0.2 GO:0045341 MHC class I biosynthetic process(GO:0045341) regulation of MHC class I biosynthetic process(GO:0045343)
0.1 0.3 GO:0010957 negative regulation of calcidiol 1-monooxygenase activity(GO:0010956) negative regulation of vitamin D biosynthetic process(GO:0010957) negative regulation of vitamin metabolic process(GO:0046137)
0.1 0.3 GO:0010447 response to acidic pH(GO:0010447)
0.1 0.8 GO:0051489 regulation of filopodium assembly(GO:0051489)
0.1 0.5 GO:0045348 positive regulation of MHC class II biosynthetic process(GO:0045348)
0.1 0.3 GO:0045066 regulatory T cell differentiation(GO:0045066)
0.1 0.3 GO:0010572 positive regulation of platelet activation(GO:0010572)
0.1 0.7 GO:0007172 signal complex assembly(GO:0007172)
0.1 0.3 GO:0031580 membrane raft polarization(GO:0001766) membrane raft distribution(GO:0031580) membrane raft localization(GO:0051665)
0.1 0.2 GO:0002313 mature B cell differentiation involved in immune response(GO:0002313)
0.1 0.2 GO:0002693 regulation of cellular extravasation(GO:0002691) positive regulation of cellular extravasation(GO:0002693)
0.1 0.2 GO:0001831 trophectodermal cellular morphogenesis(GO:0001831)
0.1 0.2 GO:0010882 regulation of cardiac muscle contraction by calcium ion signaling(GO:0010882)
0.1 0.2 GO:0042091 interleukin-10 biosynthetic process(GO:0042091) regulation of interleukin-10 biosynthetic process(GO:0045074)
0.1 0.2 GO:0072600 protein targeting to Golgi(GO:0000042) establishment of protein localization to Golgi(GO:0072600)
0.1 0.4 GO:0042989 sequestering of actin monomers(GO:0042989)
0.1 0.1 GO:0030223 neutrophil differentiation(GO:0030223)
0.1 0.2 GO:0018076 N-terminal peptidyl-lysine acetylation(GO:0018076)
0.1 0.2 GO:0050862 positive regulation of T cell receptor signaling pathway(GO:0050862)
0.1 0.2 GO:0002523 leukocyte migration involved in inflammatory response(GO:0002523)
0.1 0.4 GO:0032875 regulation of DNA endoreduplication(GO:0032875) negative regulation of DNA endoreduplication(GO:0032876) DNA endoreduplication(GO:0042023)
0.1 1.8 GO:0050690 regulation of defense response to virus by virus(GO:0050690)
0.1 0.2 GO:0002282 microglial cell activation involved in immune response(GO:0002282)
0.1 0.1 GO:0070682 proteasome regulatory particle assembly(GO:0070682)
0.1 0.1 GO:0061154 endothelial tube morphogenesis(GO:0061154)
0.1 0.5 GO:0050858 negative regulation of antigen receptor-mediated signaling pathway(GO:0050858) negative regulation of T cell receptor signaling pathway(GO:0050860)
0.1 0.2 GO:0002085 inhibition of neuroepithelial cell differentiation(GO:0002085)
0.1 0.3 GO:1904376 negative regulation of establishment of protein localization to plasma membrane(GO:0090005) negative regulation of protein localization to plasma membrane(GO:1903077) negative regulation of protein localization to cell periphery(GO:1904376)
0.1 0.4 GO:0060123 regulation of growth hormone secretion(GO:0060123)
0.1 0.3 GO:0040023 establishment of nucleus localization(GO:0040023)
0.1 0.2 GO:0090292 nuclear matrix organization(GO:0043578) nuclear matrix anchoring at nuclear membrane(GO:0090292)
0.1 0.1 GO:0002495 antigen processing and presentation of peptide antigen via MHC class II(GO:0002495)
0.1 0.1 GO:0034139 regulation of toll-like receptor 3 signaling pathway(GO:0034139)
0.1 0.2 GO:0006855 drug transmembrane transport(GO:0006855)
0.1 0.1 GO:0006269 DNA replication, synthesis of RNA primer(GO:0006269)
0.1 0.4 GO:0008653 lipopolysaccharide metabolic process(GO:0008653)
0.1 0.7 GO:0044409 entry into host cell(GO:0030260) entry into host(GO:0044409) entry into cell of other organism involved in symbiotic interaction(GO:0051806) entry into other organism involved in symbiotic interaction(GO:0051828)
0.1 0.2 GO:0030644 cellular chloride ion homeostasis(GO:0030644) chloride ion homeostasis(GO:0055064)
0.1 0.2 GO:0010867 positive regulation of triglyceride biosynthetic process(GO:0010867)
0.1 0.1 GO:0097709 connective tissue replacement involved in inflammatory response wound healing(GO:0002248) connective tissue replacement(GO:0097709)
0.1 0.1 GO:0042536 negative regulation of tumor necrosis factor biosynthetic process(GO:0042536)
0.1 0.2 GO:0006089 lactate metabolic process(GO:0006089)
0.1 1.2 GO:0045576 mast cell activation(GO:0045576)
0.1 0.5 GO:0030206 chondroitin sulfate biosynthetic process(GO:0030206)
0.1 0.2 GO:0015917 aminophospholipid transport(GO:0015917)
0.1 0.1 GO:0035520 monoubiquitinated protein deubiquitination(GO:0035520)
0.1 0.2 GO:0030187 melatonin metabolic process(GO:0030186) melatonin biosynthetic process(GO:0030187)
0.1 0.3 GO:0042508 tyrosine phosphorylation of Stat1 protein(GO:0042508)
0.1 0.1 GO:0001866 NK T cell proliferation(GO:0001866)
0.1 0.1 GO:0033622 integrin activation(GO:0033622)
0.1 0.6 GO:0043368 positive T cell selection(GO:0043368)
0.1 0.2 GO:0045349 interferon-alpha biosynthetic process(GO:0045349) regulation of interferon-alpha biosynthetic process(GO:0045354) positive regulation of interferon-alpha biosynthetic process(GO:0045356)
0.1 0.2 GO:0035751 lysosomal lumen acidification(GO:0007042) regulation of lysosomal lumen pH(GO:0035751)
0.1 0.2 GO:0006689 ganglioside catabolic process(GO:0006689)
0.1 0.1 GO:0060766 negative regulation of androgen receptor signaling pathway(GO:0060766)
0.1 0.1 GO:0002890 negative regulation of B cell mediated immunity(GO:0002713) negative regulation of immunoglobulin mediated immune response(GO:0002890)
0.1 0.3 GO:0000281 mitotic cytokinesis(GO:0000281)
0.1 0.6 GO:0000303 response to superoxide(GO:0000303)
0.1 0.1 GO:0031936 negative regulation of chromatin silencing(GO:0031936)
0.1 0.2 GO:0003351 epithelial cilium movement(GO:0003351) epithelial cilium movement involved in determination of left/right asymmetry(GO:0060287)
0.1 0.2 GO:0071168 protein localization to chromatin(GO:0071168)
0.1 0.3 GO:0045003 DNA recombinase assembly(GO:0000730) double-strand break repair via synthesis-dependent strand annealing(GO:0045003)
0.1 0.3 GO:1901797 negative regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043518) negative regulation of signal transduction by p53 class mediator(GO:1901797)
0.1 0.2 GO:0032733 positive regulation of interleukin-10 production(GO:0032733)
0.1 0.2 GO:0070670 response to interleukin-4(GO:0070670)
0.1 0.3 GO:0007256 activation of JNKK activity(GO:0007256)
0.0 0.1 GO:0007207 phospholipase C-activating G-protein coupled acetylcholine receptor signaling pathway(GO:0007207)
0.0 0.2 GO:0002507 tolerance induction(GO:0002507)
0.0 0.3 GO:0048013 ephrin receptor signaling pathway(GO:0048013)
0.0 0.3 GO:0043550 regulation of lipid kinase activity(GO:0043550)
0.0 0.1 GO:0043653 mitochondrial fragmentation involved in apoptotic process(GO:0043653)
0.0 1.0 GO:0046677 response to antibiotic(GO:0046677)
0.0 0.1 GO:0006922 obsolete cleavage of lamin involved in execution phase of apoptosis(GO:0006922)
0.0 0.0 GO:0003402 planar cell polarity pathway involved in axis elongation(GO:0003402)
0.0 0.4 GO:0000381 regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.0 0.1 GO:0051458 corticotropin secretion(GO:0051458) regulation of corticotropin secretion(GO:0051459) positive regulation of corticotropin secretion(GO:0051461)
0.0 0.2 GO:0034755 iron ion transmembrane transport(GO:0034755)
0.0 0.3 GO:0042104 positive regulation of activated T cell proliferation(GO:0042104)
0.0 0.1 GO:0006167 AMP biosynthetic process(GO:0006167)
0.0 0.2 GO:0031061 negative regulation of histone methylation(GO:0031061)
0.0 0.2 GO:0022614 membrane to membrane docking(GO:0022614)
0.0 0.2 GO:0030889 negative regulation of B cell proliferation(GO:0030889)
0.0 0.5 GO:0031648 protein destabilization(GO:0031648)
0.0 0.1 GO:0006772 thiamine metabolic process(GO:0006772)
0.0 0.3 GO:0007064 mitotic sister chromatid cohesion(GO:0007064)
0.0 0.0 GO:0051152 positive regulation of smooth muscle cell differentiation(GO:0051152)
0.0 0.1 GO:0007221 positive regulation of transcription of Notch receptor target(GO:0007221)
0.0 0.1 GO:0010216 maintenance of DNA methylation(GO:0010216)
0.0 0.2 GO:0006104 succinyl-CoA metabolic process(GO:0006104)
0.0 0.1 GO:0048478 replication fork protection(GO:0048478)
0.0 0.1 GO:0035066 positive regulation of histone acetylation(GO:0035066) positive regulation of protein acetylation(GO:1901985) positive regulation of peptidyl-lysine acetylation(GO:2000758)
0.0 0.2 GO:0043984 histone H4-K16 acetylation(GO:0043984)
0.0 0.1 GO:0051533 positive regulation of NFAT protein import into nucleus(GO:0051533)
0.0 0.1 GO:0033194 response to hydroperoxide(GO:0033194)
0.0 0.1 GO:0033632 regulation of cell-cell adhesion mediated by integrin(GO:0033632)
0.0 0.1 GO:0001779 natural killer cell differentiation(GO:0001779)
0.0 0.2 GO:0036465 synaptic vesicle recycling(GO:0036465) synaptic vesicle endocytosis(GO:0048488) clathrin-mediated endocytosis(GO:0072583)
0.0 0.1 GO:0000019 regulation of mitotic recombination(GO:0000019)
0.0 0.1 GO:0009048 dosage compensation by inactivation of X chromosome(GO:0009048)
0.0 0.2 GO:0003056 regulation of vascular smooth muscle contraction(GO:0003056)
0.0 0.1 GO:0030948 negative regulation of vascular endothelial growth factor receptor signaling pathway(GO:0030948)
0.0 0.1 GO:0050765 negative regulation of phagocytosis(GO:0050765)
0.0 0.1 GO:0045603 positive regulation of endothelial cell differentiation(GO:0045603)
0.0 2.2 GO:0050852 T cell receptor signaling pathway(GO:0050852)
0.0 1.1 GO:0042059 negative regulation of epidermal growth factor receptor signaling pathway(GO:0042059) negative regulation of ERBB signaling pathway(GO:1901185)
0.0 0.5 GO:0046854 phosphatidylinositol phosphorylation(GO:0046854)
0.0 0.1 GO:0033345 asparagine catabolic process(GO:0006530) asparagine catabolic process via L-aspartate(GO:0033345)
0.0 0.1 GO:0001661 conditioned taste aversion(GO:0001661)
0.0 0.0 GO:0060298 positive regulation of sarcomere organization(GO:0060298)
0.0 0.1 GO:0051451 myoblast migration(GO:0051451)
0.0 0.2 GO:0036473 intrinsic apoptotic signaling pathway in response to oxidative stress(GO:0008631) cell death in response to oxidative stress(GO:0036473)
0.0 0.3 GO:0008608 attachment of spindle microtubules to kinetochore(GO:0008608)
0.0 0.2 GO:0032486 Rap protein signal transduction(GO:0032486)
0.0 0.1 GO:0006003 fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.0 0.1 GO:0034626 fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.0 0.2 GO:0007023 post-chaperonin tubulin folding pathway(GO:0007023)
0.0 0.1 GO:0032070 regulation of deoxyribonuclease activity(GO:0032070)
0.0 0.1 GO:0090116 DNA methylation on cytosine(GO:0032776) C-5 methylation of cytosine(GO:0090116)
0.0 0.2 GO:0050853 B cell receptor signaling pathway(GO:0050853)
0.0 0.1 GO:0045071 negative regulation of viral genome replication(GO:0045071)
0.0 0.1 GO:0017183 peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183)
0.0 0.1 GO:0043374 CD8-positive, alpha-beta T cell activation(GO:0036037) CD8-positive, alpha-beta T cell differentiation(GO:0043374)
0.0 0.1 GO:0002538 arachidonic acid metabolite production involved in inflammatory response(GO:0002538) leukotriene production involved in inflammatory response(GO:0002540)
0.0 0.4 GO:0070536 protein K63-linked deubiquitination(GO:0070536)
0.0 0.0 GO:0010613 positive regulation of cardiac muscle hypertrophy(GO:0010613) positive regulation of muscle hypertrophy(GO:0014742)
0.0 0.1 GO:0031167 rRNA methylation(GO:0031167)
0.0 0.1 GO:0060586 multicellular organismal iron ion homeostasis(GO:0060586)
0.0 0.2 GO:0035246 peptidyl-arginine N-methylation(GO:0035246)
0.0 0.1 GO:0002532 production of molecular mediator involved in inflammatory response(GO:0002532)
0.0 0.1 GO:0042159 lipoprotein catabolic process(GO:0042159)
0.0 0.5 GO:0032012 regulation of ARF protein signal transduction(GO:0032012)
0.0 0.2 GO:0003310 pancreatic A cell differentiation(GO:0003310)
0.0 0.4 GO:0045730 respiratory burst(GO:0045730)
0.0 0.2 GO:0050847 progesterone receptor signaling pathway(GO:0050847)
0.0 0.1 GO:0015801 aromatic amino acid transport(GO:0015801)
0.0 0.1 GO:0050685 positive regulation of mRNA 3'-end processing(GO:0031442) positive regulation of mRNA processing(GO:0050685) positive regulation of mRNA metabolic process(GO:1903313)
0.0 0.1 GO:0032914 positive regulation of transforming growth factor beta1 production(GO:0032914)
0.0 0.2 GO:0006658 phosphatidylserine metabolic process(GO:0006658)
0.0 0.1 GO:0009189 deoxyribonucleoside diphosphate biosynthetic process(GO:0009189)
0.0 0.1 GO:0032715 negative regulation of interleukin-6 production(GO:0032715)
0.0 0.1 GO:1901419 regulation of response to alcohol(GO:1901419)
0.0 0.1 GO:2001012 mesenchymal cell differentiation involved in kidney development(GO:0072161) metanephric mesenchymal cell differentiation(GO:0072162) mesenchymal cell differentiation involved in renal system development(GO:2001012)
0.0 0.3 GO:0045948 positive regulation of translational initiation(GO:0045948)
0.0 0.1 GO:0060023 soft palate development(GO:0060023)
0.0 0.2 GO:0090205 positive regulation of cholesterol metabolic process(GO:0090205)
0.0 0.2 GO:0010288 response to lead ion(GO:0010288)
0.0 0.1 GO:0006528 asparagine metabolic process(GO:0006528)
0.0 0.3 GO:0042403 thyroid hormone metabolic process(GO:0042403)
0.0 0.2 GO:0005513 detection of calcium ion(GO:0005513)
0.0 0.1 GO:0007035 vacuolar acidification(GO:0007035)
0.0 0.1 GO:0045793 positive regulation of cell size(GO:0045793)
0.0 0.0 GO:0050798 activated T cell proliferation(GO:0050798)
0.0 0.1 GO:0030910 olfactory placode formation(GO:0030910) olfactory placode development(GO:0071698) olfactory placode morphogenesis(GO:0071699)
0.0 0.1 GO:0034219 carbohydrate transmembrane transport(GO:0034219)
0.0 0.5 GO:0043124 negative regulation of I-kappaB kinase/NF-kappaB signaling(GO:0043124)
0.0 0.3 GO:0048199 vesicle targeting, to, from or within Golgi(GO:0048199)
0.0 0.1 GO:0071392 cellular response to estradiol stimulus(GO:0071392)
0.0 0.2 GO:0019883 antigen processing and presentation of endogenous antigen(GO:0019883)
0.0 0.1 GO:0061030 epithelial cell differentiation involved in mammary gland alveolus development(GO:0061030)
0.0 0.2 GO:1901072 amino sugar catabolic process(GO:0046348) glucosamine-containing compound catabolic process(GO:1901072)
0.0 0.0 GO:0050686 negative regulation of mRNA processing(GO:0050686) negative regulation of mRNA metabolic process(GO:1903312)
0.0 0.1 GO:0060710 chorio-allantoic fusion(GO:0060710)
0.0 0.1 GO:0042535 positive regulation of tumor necrosis factor biosynthetic process(GO:0042535)
0.0 0.1 GO:0071157 negative regulation of cell cycle arrest(GO:0071157)
0.0 0.1 GO:0006111 regulation of gluconeogenesis(GO:0006111)
0.0 0.1 GO:0061054 dermatome development(GO:0061054)
0.0 0.1 GO:0010759 positive regulation of macrophage chemotaxis(GO:0010759)
0.0 0.1 GO:0046831 regulation of RNA export from nucleus(GO:0046831)
0.0 0.1 GO:0006883 cellular sodium ion homeostasis(GO:0006883)
0.0 0.1 GO:0006681 galactosylceramide metabolic process(GO:0006681)
0.0 0.0 GO:0002862 negative regulation of inflammatory response to antigenic stimulus(GO:0002862)
0.0 0.0 GO:0046834 lipid phosphorylation(GO:0046834)
0.0 0.1 GO:0006474 N-terminal protein amino acid acetylation(GO:0006474)
0.0 0.0 GO:2000192 negative regulation of plasma membrane long-chain fatty acid transport(GO:0010748) negative regulation of anion transmembrane transport(GO:1903960) negative regulation of fatty acid transport(GO:2000192)
0.0 0.1 GO:0070296 sarcoplasmic reticulum calcium ion transport(GO:0070296)
0.0 0.1 GO:0031646 positive regulation of neurological system process(GO:0031646)
0.0 0.1 GO:0009405 pathogenesis(GO:0009405)
0.0 0.0 GO:0002478 antigen processing and presentation of exogenous peptide antigen(GO:0002478)
0.0 0.0 GO:0032494 response to peptidoglycan(GO:0032494)
0.0 0.1 GO:0045292 mRNA cis splicing, via spliceosome(GO:0045292)
0.0 0.1 GO:0002921 negative regulation of humoral immune response(GO:0002921)
0.0 0.3 GO:0042776 mitochondrial ATP synthesis coupled proton transport(GO:0042776)
0.0 0.1 GO:0019532 oxalate transport(GO:0019532)
0.0 0.0 GO:0031060 regulation of histone methylation(GO:0031060) regulation of histone H3-K4 methylation(GO:0051569)
0.0 0.1 GO:0070935 3'-UTR-mediated mRNA stabilization(GO:0070935)
0.0 0.4 GO:0016254 preassembly of GPI anchor in ER membrane(GO:0016254)
0.0 0.3 GO:0016578 histone deubiquitination(GO:0016578)
0.0 0.1 GO:0032814 regulation of natural killer cell activation(GO:0032814)
0.0 0.4 GO:0050832 defense response to fungus(GO:0050832)
0.0 0.1 GO:0045423 regulation of granulocyte macrophage colony-stimulating factor biosynthetic process(GO:0045423)
0.0 0.3 GO:0032008 positive regulation of TOR signaling(GO:0032008)
0.0 0.1 GO:0007008 outer mitochondrial membrane organization(GO:0007008) protein import into mitochondrial outer membrane(GO:0045040)
0.0 0.0 GO:0060751 epithelial cell proliferation involved in mammary gland duct elongation(GO:0060750) branch elongation involved in mammary gland duct branching(GO:0060751)
0.0 0.2 GO:0002286 T cell activation involved in immune response(GO:0002286)
0.0 0.1 GO:0045078 positive regulation of interferon-gamma biosynthetic process(GO:0045078)
0.0 0.3 GO:0098927 early endosome to late endosome transport(GO:0045022) vesicle-mediated transport between endosomal compartments(GO:0098927)
0.0 0.1 GO:0060528 secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development(GO:0060528)
0.0 0.5 GO:0006611 protein export from nucleus(GO:0006611)
0.0 0.1 GO:0032703 negative regulation of interleukin-2 production(GO:0032703)
0.0 0.0 GO:0002438 acute inflammatory response to antigenic stimulus(GO:0002438)
0.0 0.1 GO:0048535 lymph node development(GO:0048535)
0.0 0.2 GO:0015671 oxygen transport(GO:0015671)
0.0 0.0 GO:0070602 centromeric sister chromatid cohesion(GO:0070601) regulation of centromeric sister chromatid cohesion(GO:0070602)
0.0 0.1 GO:0010988 regulation of low-density lipoprotein particle clearance(GO:0010988)
0.0 0.0 GO:0035588 adenosine receptor signaling pathway(GO:0001973) G-protein coupled purinergic receptor signaling pathway(GO:0035588)
0.0 0.1 GO:0042117 monocyte activation(GO:0042117)
0.0 0.0 GO:1902745 positive regulation of lamellipodium assembly(GO:0010592) positive regulation of lamellipodium organization(GO:1902745)
0.0 0.2 GO:0051918 negative regulation of fibrinolysis(GO:0051918)
0.0 0.0 GO:0060620 regulation of cholesterol import(GO:0060620) regulation of sterol import(GO:2000909)
0.0 0.2 GO:0006337 nucleosome disassembly(GO:0006337) chromatin disassembly(GO:0031498) protein-DNA complex disassembly(GO:0032986)
0.0 0.1 GO:0009051 pentose-phosphate shunt, oxidative branch(GO:0009051)
0.0 0.2 GO:0043508 negative regulation of JUN kinase activity(GO:0043508)
0.0 0.1 GO:0070493 thrombin receptor signaling pathway(GO:0070493)
0.0 0.2 GO:0006465 signal peptide processing(GO:0006465)
0.0 0.1 GO:0019987 obsolete negative regulation of anti-apoptosis(GO:0019987)
0.0 0.0 GO:0043268 positive regulation of potassium ion transport(GO:0043268)
0.0 0.1 GO:0002717 positive regulation of natural killer cell mediated immunity(GO:0002717) positive regulation of natural killer cell mediated cytotoxicity(GO:0045954)
0.0 0.0 GO:0010831 positive regulation of myotube differentiation(GO:0010831)
0.0 0.1 GO:0006552 leucine catabolic process(GO:0006552)
0.0 0.0 GO:0002888 positive regulation of myeloid leukocyte mediated immunity(GO:0002888)
0.0 0.2 GO:0034372 triglyceride-rich lipoprotein particle remodeling(GO:0034370) very-low-density lipoprotein particle remodeling(GO:0034372)
0.0 0.1 GO:0010587 miRNA metabolic process(GO:0010586) miRNA catabolic process(GO:0010587)
0.0 0.1 GO:0051131 chaperone-mediated protein complex assembly(GO:0051131)
0.0 0.1 GO:0006999 nuclear pore organization(GO:0006999)
0.0 0.1 GO:0010508 positive regulation of autophagy(GO:0010508)
0.0 0.4 GO:0031295 lymphocyte costimulation(GO:0031294) T cell costimulation(GO:0031295)
0.0 0.1 GO:0060158 phospholipase C-activating dopamine receptor signaling pathway(GO:0060158)
0.0 0.0 GO:0052251 induction by organism of defense response of other organism involved in symbiotic interaction(GO:0052251)
0.0 0.1 GO:0040037 negative regulation of fibroblast growth factor receptor signaling pathway(GO:0040037)
0.0 0.0 GO:0097576 vacuole fusion(GO:0097576)
0.0 0.1 GO:0060017 parathyroid gland development(GO:0060017)
0.0 0.0 GO:0006154 adenosine catabolic process(GO:0006154)
0.0 0.0 GO:0034143 regulation of toll-like receptor 4 signaling pathway(GO:0034143)
0.0 0.0 GO:0015015 heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.0 0.1 GO:0003100 regulation of systemic arterial blood pressure by endothelin(GO:0003100)
0.0 0.0 GO:0043162 ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043162)
0.0 0.5 GO:0007257 activation of JUN kinase activity(GO:0007257)
0.0 0.1 GO:0060765 regulation of androgen receptor signaling pathway(GO:0060765)
0.0 0.1 GO:0033169 histone H3-K9 demethylation(GO:0033169)
0.0 0.0 GO:0045084 positive regulation of interleukin-12 biosynthetic process(GO:0045084)
0.0 0.0 GO:0070498 interleukin-1-mediated signaling pathway(GO:0070498)
0.0 0.1 GO:0035025 positive regulation of Rho protein signal transduction(GO:0035025)
0.0 0.3 GO:0035637 transmission of nerve impulse(GO:0019226) multicellular organismal signaling(GO:0035637)
0.0 0.1 GO:0060218 hematopoietic stem cell differentiation(GO:0060218)
0.0 0.0 GO:0021853 interneuron migration from the subpallium to the cortex(GO:0021830) cerebral cortex GABAergic interneuron migration(GO:0021853) cerebral cortex GABAergic interneuron development(GO:0021894) interneuron migration(GO:1904936)
0.0 0.0 GO:0014067 negative regulation of phosphatidylinositol 3-kinase signaling(GO:0014067)
0.0 0.0 GO:1903306 negative regulation of regulated secretory pathway(GO:1903306)
0.0 0.1 GO:0001573 ganglioside metabolic process(GO:0001573)
0.0 0.1 GO:0009812 flavonoid metabolic process(GO:0009812)
0.0 0.1 GO:0042532 negative regulation of tyrosine phosphorylation of Stat3 protein(GO:0042518) negative regulation of tyrosine phosphorylation of STAT protein(GO:0042532)
0.0 0.0 GO:0055015 ventricular cardiac muscle cell development(GO:0055015)
0.0 0.1 GO:0051657 maintenance of organelle location(GO:0051657)
0.0 0.1 GO:0009113 purine nucleobase biosynthetic process(GO:0009113)
0.0 0.1 GO:0060972 left/right pattern formation(GO:0060972)
0.0 0.1 GO:0043030 regulation of macrophage activation(GO:0043030)
0.0 0.3 GO:0034199 activation of protein kinase A activity(GO:0034199)
0.0 0.2 GO:0060334 regulation of response to interferon-gamma(GO:0060330) regulation of interferon-gamma-mediated signaling pathway(GO:0060334)
0.0 0.0 GO:0009313 oligosaccharide catabolic process(GO:0009313)
0.0 0.2 GO:0051205 protein insertion into membrane(GO:0051205)
0.0 0.2 GO:0043252 sodium-independent organic anion transport(GO:0043252)
0.0 0.1 GO:0006011 UDP-glucose metabolic process(GO:0006011)
0.0 0.2 GO:0043968 histone H2A acetylation(GO:0043968)
0.0 0.1 GO:1903038 negative regulation of T cell activation(GO:0050868) negative regulation of leukocyte cell-cell adhesion(GO:1903038)
0.0 0.0 GO:0030581 intracellular transport of viral protein in host cell(GO:0019060) symbiont intracellular protein transport in host(GO:0030581) regulation by virus of viral protein levels in host cell(GO:0046719) intracellular protein transport in other organism involved in symbiotic interaction(GO:0051708)
0.0 0.0 GO:0006925 inflammatory cell apoptotic process(GO:0006925)
0.0 0.1 GO:0006013 mannose metabolic process(GO:0006013)
0.0 0.1 GO:0006610 ribosomal protein import into nucleus(GO:0006610)
0.0 0.0 GO:0072239 metanephric glomerulus development(GO:0072224) metanephric glomerulus vasculature development(GO:0072239)
0.0 0.0 GO:0040016 embryonic cleavage(GO:0040016)
0.0 0.1 GO:0051290 protein heterotetramerization(GO:0051290)
0.0 0.7 GO:0006968 cellular defense response(GO:0006968)
0.0 0.6 GO:0060333 interferon-gamma-mediated signaling pathway(GO:0060333)
0.0 0.1 GO:0008611 ether lipid biosynthetic process(GO:0008611) glycerol ether biosynthetic process(GO:0046504) ether biosynthetic process(GO:1901503)
0.0 0.1 GO:0090224 regulation of spindle organization(GO:0090224)
0.0 0.1 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.0 0.1 GO:0021854 hypothalamus development(GO:0021854)
0.0 0.0 GO:0007343 egg activation(GO:0007343)
0.0 0.1 GO:0015959 diadenosine polyphosphate metabolic process(GO:0015959)
0.0 0.2 GO:0090278 negative regulation of peptide secretion(GO:0002792) negative regulation of insulin secretion(GO:0046676) negative regulation of peptide hormone secretion(GO:0090278)
0.0 0.1 GO:0000733 DNA strand renaturation(GO:0000733)
0.0 0.0 GO:0010535 regulation of activation of JAK2 kinase activity(GO:0010534) positive regulation of activation of JAK2 kinase activity(GO:0010535)
0.0 0.2 GO:0007597 blood coagulation, intrinsic pathway(GO:0007597)
0.0 0.1 GO:0006105 succinate metabolic process(GO:0006105)
0.0 0.0 GO:0045824 negative regulation of innate immune response(GO:0045824)
0.0 0.0 GO:0051775 response to redox state(GO:0051775)
0.0 0.1 GO:0032790 ribosome disassembly(GO:0032790)
0.0 0.1 GO:0015816 glycine transport(GO:0015816)
0.0 0.1 GO:0006189 'de novo' IMP biosynthetic process(GO:0006189)
0.0 0.1 GO:0019695 choline metabolic process(GO:0019695)
0.0 0.0 GO:0048304 positive regulation of isotype switching to IgG isotypes(GO:0048304)
0.0 0.1 GO:0070389 chaperone cofactor-dependent protein refolding(GO:0070389)
0.0 0.2 GO:0034341 response to interferon-gamma(GO:0034341)
0.0 0.2 GO:0033138 positive regulation of peptidyl-serine phosphorylation(GO:0033138)
0.0 0.0 GO:0046548 retinal rod cell development(GO:0046548)
0.0 0.0 GO:0043267 negative regulation of potassium ion transport(GO:0043267)
0.0 0.0 GO:0071243 cellular response to arsenic-containing substance(GO:0071243)
0.0 0.1 GO:0009698 phenylpropanoid metabolic process(GO:0009698) coumarin metabolic process(GO:0009804)
0.0 0.1 GO:1903078 positive regulation of establishment of protein localization to plasma membrane(GO:0090004) positive regulation of protein localization to plasma membrane(GO:1903078) positive regulation of protein localization to cell periphery(GO:1904377)
0.0 0.0 GO:0043570 maintenance of DNA repeat elements(GO:0043570)
0.0 0.1 GO:0006420 arginyl-tRNA aminoacylation(GO:0006420)
0.0 0.2 GO:0043101 purine-containing compound salvage(GO:0043101)
0.0 0.0 GO:0060219 camera-type eye photoreceptor cell differentiation(GO:0060219)
0.0 0.0 GO:0010980 regulation of vitamin D 24-hydroxylase activity(GO:0010979) positive regulation of vitamin D 24-hydroxylase activity(GO:0010980)
0.0 0.0 GO:2000114 regulation of establishment of cell polarity(GO:2000114)
0.0 0.2 GO:0006379 mRNA cleavage(GO:0006379)
0.0 0.1 GO:0045737 positive regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045737) positive regulation of cyclin-dependent protein kinase activity(GO:1904031)
0.0 0.0 GO:0006828 manganese ion transport(GO:0006828)
0.0 0.1 GO:0009235 cobalamin metabolic process(GO:0009235)
0.0 0.0 GO:0031223 auditory behavior(GO:0031223)
0.0 0.0 GO:0042362 fat-soluble vitamin biosynthetic process(GO:0042362)
0.0 0.1 GO:0060056 mammary gland involution(GO:0060056)
0.0 0.0 GO:0090201 negative regulation of mitochondrion organization(GO:0010823) negative regulation of release of cytochrome c from mitochondria(GO:0090201) negative regulation of apoptotic signaling pathway(GO:2001234)
0.0 0.0 GO:0000089 mitotic metaphase(GO:0000089)
0.0 0.1 GO:0016557 peroxisome membrane biogenesis(GO:0016557)
0.0 1.2 GO:0018279 peptidyl-asparagine modification(GO:0018196) protein N-linked glycosylation via asparagine(GO:0018279)
0.0 0.2 GO:0007158 neuron cell-cell adhesion(GO:0007158)
0.0 1.1 GO:0000216 obsolete M/G1 transition of mitotic cell cycle(GO:0000216)
0.0 0.1 GO:0045672 positive regulation of osteoclast differentiation(GO:0045672)
0.0 0.0 GO:0017085 response to insecticide(GO:0017085)
0.0 0.2 GO:0018208 peptidyl-proline modification(GO:0018208)
0.0 0.0 GO:0060573 ventral spinal cord interneuron specification(GO:0021521) cell fate specification involved in pattern specification(GO:0060573)
0.0 0.0 GO:0009214 cyclic nucleotide catabolic process(GO:0009214)
0.0 0.3 GO:2000060 regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process(GO:2000058) positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process(GO:2000060)
0.0 0.1 GO:0019441 tryptophan catabolic process to kynurenine(GO:0019441)
0.0 0.1 GO:0042219 cellular modified amino acid catabolic process(GO:0042219)
0.0 0.0 GO:0019509 L-methionine biosynthetic process from methylthioadenosine(GO:0019509)
0.0 0.0 GO:0046668 regulation of retinal cell programmed cell death(GO:0046668)
0.0 0.1 GO:0015693 magnesium ion transport(GO:0015693)
0.0 0.1 GO:0006623 protein targeting to lysosome(GO:0006622) protein targeting to vacuole(GO:0006623) protein localization to lysosome(GO:0061462) protein localization to vacuole(GO:0072665) establishment of protein localization to vacuole(GO:0072666)
0.0 0.1 GO:0021683 cerebellar granular layer development(GO:0021681) cerebellar granular layer morphogenesis(GO:0021683) cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707)
0.0 0.7 GO:0071427 mRNA export from nucleus(GO:0006406) mRNA-containing ribonucleoprotein complex export from nucleus(GO:0071427)
0.0 0.1 GO:0000083 regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083)
0.0 0.1 GO:0034314 Arp2/3 complex-mediated actin nucleation(GO:0034314)
0.0 0.1 GO:0006498 N-terminal protein lipidation(GO:0006498)
0.0 0.0 GO:0008291 acetylcholine metabolic process(GO:0008291) acetate ester metabolic process(GO:1900619)
0.0 0.1 GO:0001510 RNA methylation(GO:0001510)
0.0 0.1 GO:0009209 GTP biosynthetic process(GO:0006183) UTP biosynthetic process(GO:0006228) CTP biosynthetic process(GO:0006241) pyrimidine ribonucleoside triphosphate metabolic process(GO:0009208) pyrimidine ribonucleoside triphosphate biosynthetic process(GO:0009209) CTP metabolic process(GO:0046036) UTP metabolic process(GO:0046051)
0.0 0.1 GO:0033483 gas homeostasis(GO:0033483)
0.0 0.0 GO:0070232 regulation of T cell apoptotic process(GO:0070232)
0.0 0.1 GO:0046513 ceramide biosynthetic process(GO:0046513)
0.0 0.1 GO:0006546 glycine catabolic process(GO:0006546)
0.0 0.0 GO:0031573 intra-S DNA damage checkpoint(GO:0031573)
0.0 0.0 GO:0090009 primitive streak formation(GO:0090009)
0.0 0.0 GO:0045162 clustering of voltage-gated sodium channels(GO:0045162)
0.0 0.1 GO:0051103 DNA ligation involved in DNA repair(GO:0051103)
0.0 0.1 GO:0000183 chromatin silencing at rDNA(GO:0000183)
0.0 0.0 GO:0051095 regulation of helicase activity(GO:0051095) positive regulation of helicase activity(GO:0051096)
0.0 0.0 GO:0035434 copper ion transmembrane transport(GO:0035434)
0.0 0.0 GO:0019731 antibacterial humoral response(GO:0019731)
0.0 0.1 GO:0050732 negative regulation of peptidyl-tyrosine phosphorylation(GO:0050732)
0.0 0.0 GO:0010832 negative regulation of myotube differentiation(GO:0010832)
0.0 0.0 GO:0034720 histone H3-K4 demethylation(GO:0034720)
0.0 0.0 GO:0034421 post-translational protein acetylation(GO:0034421)
0.0 0.0 GO:0006998 nuclear envelope organization(GO:0006998)
0.0 0.1 GO:0042771 intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator(GO:0042771)
0.0 0.1 GO:0046149 porphyrin-containing compound catabolic process(GO:0006787) tetrapyrrole catabolic process(GO:0033015) heme catabolic process(GO:0042167) pigment catabolic process(GO:0046149)
0.0 0.0 GO:0060197 cloaca development(GO:0035844) cloacal septation(GO:0060197)
0.0 0.0 GO:0006047 UDP-N-acetylglucosamine metabolic process(GO:0006047)
0.0 0.2 GO:1903039 positive regulation of T cell activation(GO:0050870) positive regulation of leukocyte cell-cell adhesion(GO:1903039)
0.0 0.0 GO:2000191 regulation of fatty acid transport(GO:2000191)
0.0 0.1 GO:0016180 snRNA processing(GO:0016180)
0.0 0.5 GO:0019722 calcium-mediated signaling(GO:0019722)
0.0 0.0 GO:0002068 glandular epithelial cell development(GO:0002068)
0.0 0.0 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
0.0 0.0 GO:0030309 poly-N-acetyllactosamine metabolic process(GO:0030309)
0.0 0.1 GO:0042987 amyloid precursor protein catabolic process(GO:0042987)
0.0 0.0 GO:1903020 positive regulation of glycoprotein biosynthetic process(GO:0010560) positive regulation of glycoprotein metabolic process(GO:1903020)
0.0 0.1 GO:0007076 mitotic chromosome condensation(GO:0007076)
0.0 0.3 GO:0000289 nuclear-transcribed mRNA poly(A) tail shortening(GO:0000289)
0.0 0.0 GO:0042435 indole-containing compound biosynthetic process(GO:0042435)
0.0 0.1 GO:0060760 positive regulation of response to cytokine stimulus(GO:0060760)
0.0 0.4 GO:0070646 protein modification by small protein removal(GO:0070646)
0.0 0.1 GO:0006301 postreplication repair(GO:0006301)
0.0 0.1 GO:0007340 acrosome reaction(GO:0007340)
0.0 0.0 GO:0033505 floor plate formation(GO:0021508) floor plate morphogenesis(GO:0033505)
0.0 0.0 GO:0061028 establishment of endothelial barrier(GO:0061028)
0.0 0.1 GO:0009312 oligosaccharide biosynthetic process(GO:0009312)
0.0 0.0 GO:0051594 detection of carbohydrate stimulus(GO:0009730) detection of hexose stimulus(GO:0009732) detection of monosaccharide stimulus(GO:0034287) detection of glucose(GO:0051594)
0.0 0.1 GO:0051453 regulation of intracellular pH(GO:0051453)
0.0 0.1 GO:0032210 regulation of telomere maintenance via telomerase(GO:0032210)
0.0 0.1 GO:0018065 protein-cofactor linkage(GO:0018065)
0.0 0.0 GO:0007100 mitotic centrosome separation(GO:0007100)
0.0 0.0 GO:0007144 female meiosis I(GO:0007144)
0.0 0.0 GO:0043618 regulation of transcription from RNA polymerase II promoter in response to stress(GO:0043618) regulation of transcription from RNA polymerase II promoter in response to oxidative stress(GO:0043619)
0.0 0.0 GO:0045910 negative regulation of DNA recombination(GO:0045910)
0.0 0.0 GO:0033158 regulation of protein import into nucleus, translocation(GO:0033158)
0.0 0.1 GO:0019433 triglyceride catabolic process(GO:0019433) neutral lipid catabolic process(GO:0046461) acylglycerol catabolic process(GO:0046464)
0.0 0.1 GO:0051568 histone H3-K4 methylation(GO:0051568)
0.0 0.0 GO:0034112 positive regulation of homotypic cell-cell adhesion(GO:0034112)
0.0 0.1 GO:0051602 response to electrical stimulus(GO:0051602)
0.0 0.0 GO:0060359 response to ammonium ion(GO:0060359)
0.0 0.0 GO:0042447 hormone catabolic process(GO:0042447)
0.0 0.0 GO:0001547 antral ovarian follicle growth(GO:0001547)
0.0 0.2 GO:0034612 response to tumor necrosis factor(GO:0034612)
0.0 0.0 GO:0042415 norepinephrine metabolic process(GO:0042415)
0.0 0.1 GO:0006685 sphingomyelin catabolic process(GO:0006685)
0.0 0.1 GO:0016556 mRNA modification(GO:0016556)
0.0 0.0 GO:0051927 obsolete negative regulation of calcium ion transport via voltage-gated calcium channel activity(GO:0051927)
0.0 0.1 GO:0045008 depyrimidination(GO:0045008)
0.0 0.0 GO:1904748 regulation of apoptotic process involved in morphogenesis(GO:1902337) regulation of apoptotic process involved in development(GO:1904748)
0.0 0.0 GO:0002238 response to molecule of fungal origin(GO:0002238)
0.0 0.1 GO:0035095 behavioral response to nicotine(GO:0035095)
0.0 0.0 GO:0045945 positive regulation of transcription from RNA polymerase III promoter(GO:0045945)
0.0 0.3 GO:0050772 positive regulation of axonogenesis(GO:0050772)
0.0 0.1 GO:0035121 obsolete tail morphogenesis(GO:0035121)
0.0 0.1 GO:0006903 vesicle targeting(GO:0006903)
0.0 0.0 GO:0045780 positive regulation of tissue remodeling(GO:0034105) positive regulation of bone resorption(GO:0045780) positive regulation of bone remodeling(GO:0046852)
0.0 0.2 GO:0006513 protein monoubiquitination(GO:0006513)
0.0 0.0 GO:0010107 potassium ion import(GO:0010107)
0.0 0.0 GO:0048808 male genitalia morphogenesis(GO:0048808) male anatomical structure morphogenesis(GO:0090598)
0.0 0.0 GO:0044803 multi-organism membrane organization(GO:0044803)
0.0 0.1 GO:0048169 regulation of long-term neuronal synaptic plasticity(GO:0048169)
0.0 0.1 GO:0007141 male meiosis I(GO:0007141)
0.0 0.0 GO:0035092 sperm chromatin condensation(GO:0035092)
0.0 0.1 GO:1901663 quinone biosynthetic process(GO:1901663)
0.0 0.0 GO:0009223 pyrimidine deoxyribonucleotide catabolic process(GO:0009223)
0.0 0.1 GO:0042462 eye photoreceptor cell development(GO:0042462)
0.0 0.1 GO:0007339 binding of sperm to zona pellucida(GO:0007339) sperm-egg recognition(GO:0035036)
0.0 0.0 GO:0021936 regulation of cerebellar granule cell precursor proliferation(GO:0021936) positive regulation of cerebellar granule cell precursor proliferation(GO:0021940)
0.0 0.0 GO:0050650 chondroitin sulfate proteoglycan biosynthetic process(GO:0050650)
0.0 0.0 GO:0002230 positive regulation of defense response to virus by host(GO:0002230)
0.0 0.0 GO:0008628 hormone-mediated apoptotic signaling pathway(GO:0008628)
0.0 0.1 GO:0032456 endocytic recycling(GO:0032456)
0.0 0.1 GO:0032092 positive regulation of protein binding(GO:0032092)
0.0 0.0 GO:0071436 sodium ion export(GO:0071436)
0.0 0.2 GO:0007190 activation of adenylate cyclase activity(GO:0007190)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)
0.1 0.3 GO:0070022 transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.1 0.2 GO:0000942 condensed nuclear chromosome outer kinetochore(GO:0000942)
0.1 0.5 GO:0001891 phagocytic cup(GO:0001891)
0.1 0.1 GO:0031932 TORC2 complex(GO:0031932)
0.1 0.2 GO:0072487 MSL complex(GO:0072487)
0.1 0.2 GO:0000306 extrinsic component of vacuolar membrane(GO:0000306) extrinsic component of endosome membrane(GO:0031313)
0.1 0.5 GO:0070688 MLL5-L complex(GO:0070688)
0.1 0.2 GO:0005826 actomyosin contractile ring(GO:0005826)
0.1 0.3 GO:0031088 platelet dense granule membrane(GO:0031088)
0.1 0.2 GO:0034992 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.1 0.5 GO:0042101 T cell receptor complex(GO:0042101)
0.1 0.8 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.1 0.5 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.1 0.2 GO:0043218 compact myelin(GO:0043218)
0.0 0.1 GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.0 0.5 GO:0001772 immunological synapse(GO:0001772)
0.0 0.1 GO:0032009 early phagosome(GO:0032009)
0.0 0.2 GO:0070695 FHF complex(GO:0070695)
0.0 0.1 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.0 1.4 GO:0030175 filopodium(GO:0030175)
0.0 0.0 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.0 0.2 GO:0031264 death-inducing signaling complex(GO:0031264)
0.0 0.1 GO:0031254 uropod(GO:0001931) cell trailing edge(GO:0031254)
0.0 1.2 GO:0005626 obsolete insoluble fraction(GO:0005626)
0.0 0.1 GO:0033011 perinuclear theca(GO:0033011)
0.0 0.2 GO:0000153 cytoplasmic ubiquitin ligase complex(GO:0000153)
0.0 0.2 GO:0033256 I-kappaB/NF-kappaB complex(GO:0033256)
0.0 0.2 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
0.0 0.1 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.0 0.1 GO:0032133 chromosome passenger complex(GO:0032133)
0.0 0.2 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.0 1.5 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.0 0.1 GO:0005594 collagen type IX trimer(GO:0005594)
0.0 0.4 GO:0034362 low-density lipoprotein particle(GO:0034362)
0.0 0.1 GO:0005827 polar microtubule(GO:0005827)
0.0 0.2 GO:0032839 dendrite cytoplasm(GO:0032839)
0.0 0.2 GO:0044224 juxtaparanode region of axon(GO:0044224)
0.0 0.2 GO:0000796 condensin complex(GO:0000796)
0.0 0.3 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.0 0.1 GO:0070820 tertiary granule(GO:0070820)
0.0 0.1 GO:0030895 apolipoprotein B mRNA editing enzyme complex(GO:0030895)
0.0 0.1 GO:0016593 Cdc73/Paf1 complex(GO:0016593)
0.0 0.1 GO:0035189 Rb-E2F complex(GO:0035189)
0.0 0.1 GO:0000800 lateral element(GO:0000800)
0.0 0.3 GO:0033276 transcription factor TFTC complex(GO:0033276)
0.0 0.2 GO:0005845 mRNA cap binding complex(GO:0005845) RNA cap binding complex(GO:0034518)
0.0 0.1 GO:0000137 Golgi cis cisterna(GO:0000137)
0.0 0.2 GO:0000125 PCAF complex(GO:0000125)
0.0 0.2 GO:0042627 chylomicron(GO:0042627)
0.0 0.1 GO:0044462 external encapsulating structure part(GO:0044462)
0.0 0.3 GO:0016471 vacuolar proton-transporting V-type ATPase complex(GO:0016471)
0.0 0.5 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 0.1 GO:0071438 invadopodium membrane(GO:0071438)
0.0 0.2 GO:0005664 origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.0 0.4 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.0 0.2 GO:0008290 F-actin capping protein complex(GO:0008290)
0.0 0.2 GO:0071778 obsolete WINAC complex(GO:0071778)
0.0 0.1 GO:0005686 U2 snRNP(GO:0005686)
0.0 0.1 GO:0005721 pericentric heterochromatin(GO:0005721)
0.0 0.1 GO:0005662 DNA replication factor A complex(GO:0005662)
0.0 0.2 GO:0043020 NADPH oxidase complex(GO:0043020)
0.0 0.1 GO:0031465 Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
0.0 0.1 GO:1990316 ATG1/ULK1 kinase complex(GO:1990316)
0.0 0.1 GO:0030062 mitochondrial tricarboxylic acid cycle enzyme complex(GO:0030062)
0.0 0.5 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.0 0.2 GO:0019773 proteasome core complex, alpha-subunit complex(GO:0019773)
0.0 0.3 GO:0035631 CD40 receptor complex(GO:0035631)
0.0 0.2 GO:0042555 MCM complex(GO:0042555)
0.0 0.2 GO:0031080 nuclear pore outer ring(GO:0031080)
0.0 0.4 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)
0.0 0.3 GO:0005720 nuclear heterochromatin(GO:0005720)
0.0 0.2 GO:0005697 telomerase holoenzyme complex(GO:0005697)
0.0 0.1 GO:0000300 obsolete peripheral to membrane of membrane fraction(GO:0000300)
0.0 0.1 GO:0061200 clathrin-sculpted gamma-aminobutyric acid transport vesicle(GO:0061200) clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane(GO:0061202)
0.0 0.1 GO:0005797 Golgi medial cisterna(GO:0005797)
0.0 0.1 GO:0031371 ubiquitin conjugating enzyme complex(GO:0031371)
0.0 0.1 GO:0000791 euchromatin(GO:0000791)
0.0 0.1 GO:0010369 chromocenter(GO:0010369)
0.0 2.5 GO:0009897 external side of plasma membrane(GO:0009897)
0.0 0.2 GO:0032039 integrator complex(GO:0032039)
0.0 0.1 GO:0032590 dendrite membrane(GO:0032590)
0.0 0.4 GO:0016328 lateral plasma membrane(GO:0016328)
0.0 0.1 GO:0043190 ATP-binding cassette (ABC) transporter complex(GO:0043190)
0.0 0.1 GO:0045179 apical cortex(GO:0045179)
0.0 0.1 GO:0048786 presynaptic active zone(GO:0048786)
0.0 0.1 GO:0008537 proteasome activator complex(GO:0008537)
0.0 0.1 GO:0032389 MutLalpha complex(GO:0032389)
0.0 0.2 GO:0031105 septin complex(GO:0031105) septin cytoskeleton(GO:0032156)
0.0 0.3 GO:0030530 obsolete heterogeneous nuclear ribonucleoprotein complex(GO:0030530)
0.0 0.1 GO:0008282 ATP-sensitive potassium channel complex(GO:0008282)
0.0 0.1 GO:0070188 obsolete Stn1-Ten1 complex(GO:0070188)
0.0 0.2 GO:0060293 P granule(GO:0043186) pole plasm(GO:0045495) germ plasm(GO:0060293)
0.0 0.1 GO:0005883 neurofilament(GO:0005883)
0.0 0.1 GO:0045120 pronucleus(GO:0045120)
0.0 0.1 GO:0033553 rDNA heterochromatin(GO:0033553)
0.0 0.1 GO:0031305 integral component of mitochondrial inner membrane(GO:0031305)
0.0 0.2 GO:0005852 eukaryotic translation initiation factor 3 complex(GO:0005852)
0.0 0.1 GO:0001741 XY body(GO:0001741)
0.0 0.1 GO:0005863 striated muscle myosin thick filament(GO:0005863)
0.0 0.1 GO:0042629 mast cell granule(GO:0042629)
0.0 0.1 GO:0005682 U5 snRNP(GO:0005682)
0.0 0.1 GO:0030904 retromer complex(GO:0030904)
0.0 0.8 GO:0016605 PML body(GO:0016605)
0.0 0.1 GO:0005641 nuclear envelope lumen(GO:0005641)
0.0 0.1 GO:0030877 beta-catenin destruction complex(GO:0030877)
0.0 0.1 GO:0070776 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.0 0.0 GO:0031304 intrinsic component of mitochondrial inner membrane(GO:0031304)
0.0 0.1 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 0.1 GO:0031464 Cul4A-RING E3 ubiquitin ligase complex(GO:0031464)
0.0 0.1 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.0 0.2 GO:0016235 aggresome(GO:0016235)
0.0 0.1 GO:0005750 mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
0.0 0.1 GO:0030897 HOPS complex(GO:0030897)
0.0 0.1 GO:0070761 pre-snoRNP complex(GO:0070761)
0.0 0.1 GO:0000275 mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275)
0.0 0.0 GO:0001652 granular component(GO:0001652)
0.0 0.4 GO:0030667 secretory granule membrane(GO:0030667)
0.0 0.0 GO:0031205 endoplasmic reticulum Sec complex(GO:0031205)
0.0 0.1 GO:0019907 cyclin-dependent protein kinase activating kinase holoenzyme complex(GO:0019907)
0.0 0.1 GO:0008180 COP9 signalosome(GO:0008180)
0.0 0.1 GO:0005652 nuclear lamina(GO:0005652)
0.0 0.0 GO:0016533 cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533)
0.0 0.1 GO:0001740 Barr body(GO:0001740)
0.0 0.0 GO:0000792 heterochromatin(GO:0000792)
0.0 0.1 GO:0031010 ISWI-type complex(GO:0031010)
0.0 0.1 GO:0031616 spindle pole centrosome(GO:0031616)
0.0 0.0 GO:0008540 proteasome regulatory particle, base subcomplex(GO:0008540)
0.0 0.2 GO:0000315 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.0 0.1 GO:0032279 asymmetric synapse(GO:0032279) neuron to neuron synapse(GO:0098984)
0.0 0.1 GO:0005753 mitochondrial proton-transporting ATP synthase complex(GO:0005753)
0.0 0.1 GO:0005839 proteasome core complex(GO:0005839)
0.0 0.6 GO:0031901 early endosome membrane(GO:0031901)
0.0 0.0 GO:0033179 proton-transporting V-type ATPase, V0 domain(GO:0033179)
0.0 0.3 GO:0031526 brush border membrane(GO:0031526)
0.0 0.1 GO:0000346 transcription export complex(GO:0000346)
0.0 0.0 GO:0000803 sex chromosome(GO:0000803)
0.0 0.1 GO:0035267 NuA4 histone acetyltransferase complex(GO:0035267)
0.0 0.1 GO:0005671 Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
0.0 0.4 GO:0009295 nucleoid(GO:0009295)
0.0 0.1 GO:0022624 proteasome accessory complex(GO:0022624)
0.0 0.1 GO:0031083 BLOC complex(GO:0031082) BLOC-1 complex(GO:0031083)
0.0 0.4 GO:0000502 proteasome complex(GO:0000502)
0.0 0.0 GO:0030688 preribosome, small subunit precursor(GO:0030688)
0.0 0.0 GO:0045323 interleukin-1 receptor complex(GO:0045323)
0.0 0.2 GO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
0.0 0.0 GO:0072357 PTW/PP1 phosphatase complex(GO:0072357)
0.0 0.0 GO:0034045 pre-autophagosomal structure membrane(GO:0034045)
0.0 0.0 GO:1902562 H4/H2A histone acetyltransferase complex(GO:0043189) H4 histone acetyltransferase complex(GO:1902562)
0.0 0.0 GO:0042824 MHC class I peptide loading complex(GO:0042824)
0.0 0.1 GO:0008278 cohesin complex(GO:0008278)
0.0 0.1 GO:0005669 transcription factor TFIID complex(GO:0005669)
0.0 0.1 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.0 0.0 GO:0000124 SAGA complex(GO:0000124)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.6 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.2 0.5 GO:0035184 histone threonine kinase activity(GO:0035184)
0.2 0.6 GO:0047238 glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity(GO:0047238)
0.1 0.4 GO:0033691 sialic acid binding(GO:0033691)
0.1 0.8 GO:0016494 C-X-C chemokine receptor activity(GO:0016494)
0.1 0.4 GO:0004465 lipoprotein lipase activity(GO:0004465)
0.1 0.4 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.1 1.1 GO:0016493 C-C chemokine receptor activity(GO:0016493)
0.1 1.3 GO:0004697 protein kinase C activity(GO:0004697)
0.1 0.3 GO:0003836 beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.1 0.5 GO:0052813 phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) phosphatidylinositol bisphosphate kinase activity(GO:0052813)
0.1 0.1 GO:0042608 T cell receptor binding(GO:0042608)
0.1 0.4 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.1 0.3 GO:0004911 interleukin-2 receptor activity(GO:0004911)
0.1 0.3 GO:0016309 1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
0.1 0.4 GO:0030284 estrogen receptor activity(GO:0030284)
0.1 0.6 GO:0070087 chromo shadow domain binding(GO:0070087)
0.1 0.3 GO:0047623 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.1 0.4 GO:0031013 troponin I binding(GO:0031013)
0.1 0.2 GO:0016842 amidine-lyase activity(GO:0016842)
0.1 0.2 GO:0030375 thyroid hormone receptor coactivator activity(GO:0030375)
0.1 0.7 GO:0034593 phosphatidylinositol bisphosphate phosphatase activity(GO:0034593)
0.1 1.2 GO:0030159 receptor signaling complex scaffold activity(GO:0030159)
0.1 0.3 GO:0004062 aryl sulfotransferase activity(GO:0004062)
0.1 0.4 GO:0005314 high-affinity glutamate transmembrane transporter activity(GO:0005314)
0.1 0.2 GO:0008545 JUN kinase kinase activity(GO:0008545)
0.1 0.1 GO:0016314 phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity(GO:0016314)
0.1 1.6 GO:0045028 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.1 0.2 GO:0047756 chondroitin 4-sulfotransferase activity(GO:0047756)
0.1 0.8 GO:0005095 GTPase inhibitor activity(GO:0005095)
0.1 0.2 GO:0043398 HLH domain binding(GO:0043398)
0.1 0.2 GO:0000247 C-8 sterol isomerase activity(GO:0000247)
0.1 1.0 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.1 0.2 GO:0070053 thrombospondin receptor activity(GO:0070053)
0.1 0.3 GO:0005131 growth hormone receptor binding(GO:0005131)
0.1 0.2 GO:0015925 galactosidase activity(GO:0015925)
0.1 1.2 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.1 0.6 GO:0015924 mannosyl-oligosaccharide mannosidase activity(GO:0015924)
0.1 0.5 GO:0004579 dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.1 0.3 GO:0005381 iron ion transmembrane transporter activity(GO:0005381)
0.1 0.1 GO:0032139 dinucleotide insertion or deletion binding(GO:0032139)
0.1 0.4 GO:0030332 cyclin binding(GO:0030332)
0.1 0.3 GO:0001784 phosphotyrosine binding(GO:0001784)
0.1 0.4 GO:0015271 outward rectifier potassium channel activity(GO:0015271)
0.1 0.2 GO:0004591 oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591)
0.1 0.2 GO:0004719 protein-L-isoaspartate (D-aspartate) O-methyltransferase activity(GO:0004719)
0.0 0.2 GO:0004774 succinate-CoA ligase activity(GO:0004774)
0.0 0.3 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.0 0.1 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.0 0.2 GO:0004950 G-protein coupled chemoattractant receptor activity(GO:0001637) chemokine receptor activity(GO:0004950)
0.0 0.1 GO:0003910 DNA ligase activity(GO:0003909) DNA ligase (ATP) activity(GO:0003910)
0.0 0.2 GO:0016004 phospholipase activator activity(GO:0016004)
0.0 0.1 GO:0004351 glutamate decarboxylase activity(GO:0004351)
0.0 0.4 GO:0019864 IgG binding(GO:0019864)
0.0 0.0 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
0.0 0.5 GO:0051018 protein kinase A binding(GO:0051018)
0.0 0.2 GO:0001609 G-protein coupled adenosine receptor activity(GO:0001609)
0.0 0.1 GO:0042156 obsolete zinc-mediated transcriptional activator activity(GO:0042156)
0.0 2.1 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.0 0.1 GO:0050544 arachidonic acid binding(GO:0050544)
0.0 0.0 GO:0035197 siRNA binding(GO:0035197)
0.0 0.2 GO:0008526 phosphatidylinositol transporter activity(GO:0008526)
0.0 0.1 GO:0008474 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.0 0.1 GO:0050253 retinyl-palmitate esterase activity(GO:0050253)
0.0 0.5 GO:0031593 polyubiquitin binding(GO:0031593)
0.0 0.1 GO:0060230 lipoprotein lipase activator activity(GO:0060230)
0.0 0.2 GO:0008649 rRNA methyltransferase activity(GO:0008649)
0.0 0.0 GO:0010861 thyroid hormone receptor activator activity(GO:0010861)
0.0 0.1 GO:0031628 opioid receptor binding(GO:0031628)
0.0 0.6 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0 0.1 GO:0003953 NAD+ nucleosidase activity(GO:0003953)
0.0 0.9 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.0 0.2 GO:0015057 thrombin receptor activity(GO:0015057)
0.0 0.1 GO:0034481 chondroitin sulfotransferase activity(GO:0034481)
0.0 0.2 GO:0004046 aminoacylase activity(GO:0004046)
0.0 0.9 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435)
0.0 0.2 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.0 0.2 GO:0031435 mitogen-activated protein kinase kinase kinase binding(GO:0031435)
0.0 0.2 GO:0004904 interferon receptor activity(GO:0004904)
0.0 0.2 GO:0030955 potassium ion binding(GO:0030955)
0.0 0.3 GO:0016274 arginine N-methyltransferase activity(GO:0016273) protein-arginine N-methyltransferase activity(GO:0016274)
0.0 0.2 GO:0034452 dynactin binding(GO:0034452)
0.0 0.1 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.0 0.1 GO:0004607 phosphatidylcholine-sterol O-acyltransferase activity(GO:0004607)
0.0 0.3 GO:0046625 sphingolipid binding(GO:0046625)
0.0 0.2 GO:0004568 chitinase activity(GO:0004568)
0.0 0.0 GO:0035014 phosphatidylinositol 3-kinase regulator activity(GO:0035014)
0.0 0.2 GO:0031701 angiotensin receptor binding(GO:0031701)
0.0 1.8 GO:0008301 DNA binding, bending(GO:0008301)
0.0 0.3 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.0 1.1 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.0 0.1 GO:0004974 leukotriene receptor activity(GO:0004974)
0.0 0.2 GO:0016520 growth hormone-releasing hormone receptor activity(GO:0016520)
0.0 0.4 GO:0008373 sialyltransferase activity(GO:0008373)
0.0 0.3 GO:0005338 nucleotide-sugar transmembrane transporter activity(GO:0005338)
0.0 0.1 GO:0005087 Ran guanyl-nucleotide exchange factor activity(GO:0005087)
0.0 0.1 GO:0004060 arylamine N-acetyltransferase activity(GO:0004060)
0.0 0.1 GO:0001758 retinal dehydrogenase activity(GO:0001758)
0.0 0.3 GO:0048531 beta-1,3-galactosyltransferase activity(GO:0048531)
0.0 0.1 GO:0098847 single-stranded telomeric DNA binding(GO:0043047) sequence-specific single stranded DNA binding(GO:0098847)
0.0 0.1 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454)
0.0 0.1 GO:0048156 tau protein binding(GO:0048156)
0.0 0.2 GO:0003688 DNA replication origin binding(GO:0003688)
0.0 0.2 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.0 0.2 GO:0005522 profilin binding(GO:0005522)
0.0 0.4 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.0 0.2 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.0 0.2 GO:0050733 RS domain binding(GO:0050733)
0.0 0.2 GO:0015347 sodium-independent organic anion transmembrane transporter activity(GO:0015347)
0.0 0.4 GO:0005528 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.0 0.1 GO:0070492 oligosaccharide binding(GO:0070492)
0.0 0.2 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.0 0.1 GO:0042910 xenobiotic-transporting ATPase activity(GO:0008559) xenobiotic transporter activity(GO:0042910)
0.0 0.2 GO:0050664 superoxide-generating NADPH oxidase activity(GO:0016175) oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor(GO:0050664)
0.0 0.1 GO:0000064 L-ornithine transmembrane transporter activity(GO:0000064)
0.0 0.3 GO:0046875 ephrin receptor binding(GO:0046875)
0.0 0.1 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.0 0.3 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.0 0.2 GO:0042043 neurexin family protein binding(GO:0042043)
0.0 0.2 GO:0008889 glycerophosphodiester phosphodiesterase activity(GO:0008889)
0.0 0.1 GO:0004311 farnesyltranstransferase activity(GO:0004311)
0.0 0.1 GO:0005436 sodium:phosphate symporter activity(GO:0005436)
0.0 0.2 GO:0005092 GDP-dissociation inhibitor activity(GO:0005092)
0.0 0.1 GO:0050815 phosphoserine binding(GO:0050815)
0.0 0.0 GO:0031434 mitogen-activated protein kinase kinase binding(GO:0031434)
0.0 0.1 GO:0016174 NAD(P)H oxidase activity(GO:0016174)
0.0 0.1 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.0 0.1 GO:0055103 ligase regulator activity(GO:0055103) ubiquitin-protein transferase regulator activity(GO:0055106)
0.0 0.1 GO:0008420 CTD phosphatase activity(GO:0008420)
0.0 0.1 GO:0008486 diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486)
0.0 0.3 GO:0004065 arylsulfatase activity(GO:0004065)
0.0 0.2 GO:0008171 O-methyltransferase activity(GO:0008171)
0.0 0.1 GO:0004459 L-lactate dehydrogenase activity(GO:0004459)
0.0 0.0 GO:0015272 ATP-activated inward rectifier potassium channel activity(GO:0015272)
0.0 0.1 GO:0008174 mRNA methyltransferase activity(GO:0008174)
0.0 0.1 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0 0.0 GO:0008192 RNA guanylyltransferase activity(GO:0008192)
0.0 0.0 GO:0015440 oligopeptide-transporting ATPase activity(GO:0015421) peptide-transporting ATPase activity(GO:0015440)
0.0 0.0 GO:0031685 adenosine receptor binding(GO:0031685)
0.0 0.2 GO:0016922 ligand-dependent nuclear receptor binding(GO:0016922)
0.0 0.1 GO:0005521 lamin binding(GO:0005521)
0.0 0.3 GO:0030742 GTP-dependent protein binding(GO:0030742)
0.0 0.5 GO:0035064 methylated histone binding(GO:0035064)
0.0 0.1 GO:0043142 single-stranded DNA-dependent ATPase activity(GO:0043142)
0.0 0.1 GO:0032137 guanine/thymine mispair binding(GO:0032137)
0.0 0.1 GO:0030911 TPR domain binding(GO:0030911)
0.0 0.1 GO:0030368 interleukin-17 receptor activity(GO:0030368)
0.0 0.1 GO:0004659 prenyltransferase activity(GO:0004659)
0.0 0.1 GO:0016882 cyclo-ligase activity(GO:0016882)
0.0 0.1 GO:0004563 beta-N-acetylhexosaminidase activity(GO:0004563)
0.0 0.0 GO:0030881 beta-2-microglobulin binding(GO:0030881)
0.0 0.2 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.0 0.1 GO:0015379 potassium:chloride symporter activity(GO:0015379)
0.0 0.1 GO:0017176 phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.0 0.1 GO:0000739 obsolete DNA strand annealing activity(GO:0000739)
0.0 1.4 GO:0004221 obsolete ubiquitin thiolesterase activity(GO:0004221)
0.0 0.0 GO:0019958 C-X-C chemokine binding(GO:0019958) interleukin-8 binding(GO:0019959)
0.0 0.1 GO:0008109 N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109)
0.0 0.1 GO:0031210 phosphatidylcholine binding(GO:0031210)
0.0 0.1 GO:0003873 6-phosphofructo-2-kinase activity(GO:0003873)
0.0 0.1 GO:0034713 type I transforming growth factor beta receptor binding(GO:0034713)
0.0 0.1 GO:0004677 DNA-dependent protein kinase activity(GO:0004677)
0.0 0.1 GO:0070513 death domain binding(GO:0070513)
0.0 0.1 GO:0004706 JUN kinase kinase kinase activity(GO:0004706)
0.0 0.0 GO:0015252 hydrogen ion channel activity(GO:0015252)
0.0 0.1 GO:0005375 copper ion transmembrane transporter activity(GO:0005375)
0.0 0.2 GO:0017075 syntaxin-1 binding(GO:0017075)
0.0 0.7 GO:0003725 double-stranded RNA binding(GO:0003725)
0.0 0.0 GO:0001846 opsonin binding(GO:0001846)
0.0 0.0 GO:0005219 ryanodine-sensitive calcium-release channel activity(GO:0005219)
0.0 0.1 GO:0070097 delta-catenin binding(GO:0070097)
0.0 0.6 GO:0003823 antigen binding(GO:0003823)
0.0 0.0 GO:0004457 lactate dehydrogenase activity(GO:0004457)
0.0 1.7 GO:0017124 SH3 domain binding(GO:0017124)
0.0 0.1 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.0 0.1 GO:0042288 MHC class I protein binding(GO:0042288)
0.0 0.1 GO:0016149 translation release factor activity, codon specific(GO:0016149)
0.0 0.2 GO:0042923 neuropeptide binding(GO:0042923)
0.0 0.1 GO:0004652 polynucleotide adenylyltransferase activity(GO:0004652)
0.0 0.0 GO:0004946 bombesin receptor activity(GO:0004946)
0.0 0.1 GO:0030229 very-low-density lipoprotein particle receptor activity(GO:0030229)
0.0 0.1 GO:0051766 inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440) inositol trisphosphate kinase activity(GO:0051766)
0.0 0.2 GO:0050700 CARD domain binding(GO:0050700)
0.0 0.4 GO:0070003 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.0 0.1 GO:0030292 protein tyrosine kinase inhibitor activity(GO:0030292)
0.0 0.2 GO:0030276 clathrin binding(GO:0030276)
0.0 0.0 GO:0000268 peroxisome targeting sequence binding(GO:0000268)
0.0 0.1 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.0 0.1 GO:0016774 phosphotransferase activity, carboxyl group as acceptor(GO:0016774)
0.0 0.1 GO:0042162 telomeric DNA binding(GO:0042162)
0.0 0.2 GO:0035251 UDP-glucosyltransferase activity(GO:0035251)
0.0 0.1 GO:0004127 cytidylate kinase activity(GO:0004127)
0.0 0.2 GO:0004016 adenylate cyclase activity(GO:0004016)
0.0 0.1 GO:0000405 bubble DNA binding(GO:0000405)
0.0 0.1 GO:0016308 1-phosphatidylinositol-4-phosphate 5-kinase activity(GO:0016308)
0.0 0.1 GO:0004449 isocitrate dehydrogenase (NAD+) activity(GO:0004449)
0.0 0.0 GO:0060228 phosphatidylcholine-sterol O-acyltransferase activator activity(GO:0060228)
0.0 0.3 GO:0048487 beta-tubulin binding(GO:0048487)
0.0 0.1 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.0 0.1 GO:0004047 aminomethyltransferase activity(GO:0004047)
0.0 0.1 GO:0008536 Ran GTPase binding(GO:0008536)
0.0 0.1 GO:0008494 translation activator activity(GO:0008494)
0.0 0.1 GO:0030306 ADP-ribosylation factor binding(GO:0030306)
0.0 0.1 GO:0001727 lipid kinase activity(GO:0001727)
0.0 0.2 GO:0005031 tumor necrosis factor-activated receptor activity(GO:0005031)
0.0 0.1 GO:0003720 telomerase activity(GO:0003720) RNA-directed DNA polymerase activity(GO:0003964)
0.0 0.1 GO:0017159 pantetheine hydrolase activity(GO:0017159)
0.0 0.3 GO:0003755 peptidyl-prolyl cis-trans isomerase activity(GO:0003755)
0.0 0.3 GO:0008601 protein phosphatase type 2A regulator activity(GO:0008601)
0.0 0.1 GO:0008821 crossover junction endodeoxyribonuclease activity(GO:0008821)
0.0 0.2 GO:0043022 ribosome binding(GO:0043022)
0.0 0.1 GO:0043425 bHLH transcription factor binding(GO:0043425)
0.0 0.0 GO:0004999 vasoactive intestinal polypeptide receptor activity(GO:0004999)
0.0 0.1 GO:0004814 arginine-tRNA ligase activity(GO:0004814)
0.0 0.3 GO:0004889 acetylcholine-activated cation-selective channel activity(GO:0004889)
0.0 0.1 GO:0003988 acetyl-CoA C-acyltransferase activity(GO:0003988)
0.0 0.0 GO:0070653 high-density lipoprotein particle receptor binding(GO:0070653)
0.0 0.1 GO:0004663 Rab geranylgeranyltransferase activity(GO:0004663)
0.0 0.1 GO:0019788 NEDD8 transferase activity(GO:0019788)
0.0 0.1 GO:0008048 calcium sensitive guanylate cyclase activator activity(GO:0008048)
0.0 0.1 GO:0004340 glucokinase activity(GO:0004340)
0.0 0.1 GO:0004994 somatostatin receptor activity(GO:0004994)
0.0 0.1 GO:0015321 sodium-dependent phosphate transmembrane transporter activity(GO:0015321)
0.0 0.1 GO:0015385 sodium:proton antiporter activity(GO:0015385)
0.0 0.2 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.0 0.4 GO:0004693 cyclin-dependent protein serine/threonine kinase activity(GO:0004693) cyclin-dependent protein kinase activity(GO:0097472)
0.0 0.5 GO:0003697 single-stranded DNA binding(GO:0003697)
0.0 0.1 GO:0004035 alkaline phosphatase activity(GO:0004035)
0.0 0.0 GO:0004949 cannabinoid receptor activity(GO:0004949)
0.0 0.4 GO:0019003 GDP binding(GO:0019003)
0.0 0.0 GO:0016721 superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
0.0 0.0 GO:0016728 ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
0.0 0.0 GO:0004967 glucagon receptor activity(GO:0004967)
0.0 0.1 GO:0004017 adenylate kinase activity(GO:0004017)
0.0 0.1 GO:0061630 ubiquitin-ubiquitin ligase activity(GO:0034450) ubiquitin protein ligase activity(GO:0061630) ubiquitin-like protein ligase activity(GO:0061659)
0.0 0.1 GO:0017127 cholesterol transporter activity(GO:0017127)
0.0 0.4 GO:0001104 RNA polymerase II transcription cofactor activity(GO:0001104)
0.0 0.2 GO:0005246 calcium channel regulator activity(GO:0005246)
0.0 0.1 GO:0016997 exo-alpha-sialidase activity(GO:0004308) alpha-sialidase activity(GO:0016997)
0.0 0.1 GO:0043014 alpha-tubulin binding(GO:0043014)
0.0 0.0 GO:0030023 extracellular matrix constituent conferring elasticity(GO:0030023) structural molecule activity conferring elasticity(GO:0097493)
0.0 0.1 GO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.0 0.5 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.0 0.1 GO:0004427 inorganic diphosphatase activity(GO:0004427)
0.0 0.0 GO:0070215 obsolete MDM2 binding(GO:0070215)
0.0 0.0 GO:0031849 olfactory receptor binding(GO:0031849)
0.0 0.1 GO:0070579 methylcytosine dioxygenase activity(GO:0070579)
0.0 0.2 GO:0016892 endoribonuclease activity, producing 3'-phosphomonoesters(GO:0016892)
0.0 0.1 GO:0017025 TBP-class protein binding(GO:0017025)
0.0 0.1 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.0 0.0 GO:0032453 histone demethylase activity (H3-K4 specific)(GO:0032453) histone demethylase activity (H3-dimethyl-K4 specific)(GO:0034648)
0.0 0.1 GO:0051636 obsolete Gram-negative bacterial cell surface binding(GO:0051636)
0.0 0.1 GO:0060590 ATPase regulator activity(GO:0060590)
0.0 0.0 GO:0052658 inositol-1,4,5-trisphosphate 5-phosphatase activity(GO:0052658) inositol-1,3,4,5-tetrakisphosphate 5-phosphatase activity(GO:0052659)
0.0 0.2 GO:0004683 calmodulin-dependent protein kinase activity(GO:0004683)
0.0 0.1 GO:0016884 carbon-nitrogen ligase activity, with glutamine as amido-N-donor(GO:0016884)
0.0 0.1 GO:0051787 misfolded protein binding(GO:0051787)
0.0 0.4 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)
0.0 0.1 GO:0030983 mismatched DNA binding(GO:0030983)
0.0 0.3 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.0 0.1 GO:0004550 nucleoside diphosphate kinase activity(GO:0004550)
0.0 0.1 GO:0008195 phosphatidate phosphatase activity(GO:0008195)
0.0 0.0 GO:0048495 Roundabout binding(GO:0048495)
0.0 0.1 GO:0016423 tRNA (guanine) methyltransferase activity(GO:0016423)
0.0 0.0 GO:0015194 L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.0 0.3 GO:0019205 nucleobase-containing compound kinase activity(GO:0019205)
0.0 0.6 GO:0004197 cysteine-type endopeptidase activity(GO:0004197)
0.0 0.1 GO:0016634 oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor(GO:0016634)
0.0 0.1 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.0 0.0 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
0.0 0.1 GO:0070567 cytidylyltransferase activity(GO:0070567)
0.0 0.2 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.0 0.0 GO:0004952 dopamine neurotransmitter receptor activity(GO:0004952)
0.0 0.0 GO:0004582 dolichyl-phosphate beta-D-mannosyltransferase activity(GO:0004582)
0.0 0.0 GO:0047894 flavonol 3-sulfotransferase activity(GO:0047894)
0.0 0.1 GO:0016778 diphosphotransferase activity(GO:0016778)
0.0 0.2 GO:0003746 translation elongation factor activity(GO:0003746)
0.0 0.3 GO:0003678 DNA helicase activity(GO:0003678)
0.0 0.2 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.0 0.0 GO:0044769 ATPase activity, coupled to transmembrane movement of ions, rotational mechanism(GO:0044769)
0.0 0.0 GO:0031177 phosphopantetheine binding(GO:0031177)
0.0 0.1 GO:0030553 cGMP binding(GO:0030553)
0.0 0.1 GO:0031996 thioesterase binding(GO:0031996)
0.0 0.0 GO:0004704 NF-kappaB-inducing kinase activity(GO:0004704)
0.0 0.0 GO:0015278 calcium-release channel activity(GO:0015278) ligand-gated calcium channel activity(GO:0099604)
0.0 0.0 GO:0003747 translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079)
0.0 0.0 GO:0005143 interleukin-12 receptor binding(GO:0005143)
0.0 0.0 GO:0016362 activin receptor activity, type II(GO:0016362)
0.0 0.0 GO:0019166 trans-2-enoyl-CoA reductase (NADPH) activity(GO:0019166)
0.0 0.1 GO:0003756 protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864)
0.0 0.1 GO:0005041 low-density lipoprotein receptor activity(GO:0005041)
0.0 0.0 GO:0016748 succinyltransferase activity(GO:0016748)
0.0 0.1 GO:0015185 gamma-aminobutyric acid transmembrane transporter activity(GO:0015185)
0.0 0.0 GO:0017081 chloride channel regulator activity(GO:0017081)
0.0 0.1 GO:0042834 peptidoglycan binding(GO:0042834)
0.0 0.1 GO:0051721 protein phosphatase 2A binding(GO:0051721)
0.0 0.0 GO:0010485 H4 histone acetyltransferase activity(GO:0010485)
0.0 0.1 GO:0001848 complement binding(GO:0001848)
0.0 0.0 GO:0003917 DNA topoisomerase type I activity(GO:0003917)
0.0 0.1 GO:0003711 obsolete transcription elongation regulator activity(GO:0003711)
0.0 0.0 GO:0017089 glycolipid transporter activity(GO:0017089)
0.0 0.0 GO:0016776 phosphotransferase activity, phosphate group as acceptor(GO:0016776)
0.0 0.1 GO:0032395 MHC class II receptor activity(GO:0032395)
0.0 0.1 GO:0016833 oxo-acid-lyase activity(GO:0016833)
0.0 0.0 GO:0047631 ADP-ribose diphosphatase activity(GO:0047631)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.1 PID LYMPH ANGIOGENESIS PATHWAY VEGFR3 signaling in lymphatic endothelium
0.1 1.7 PID TCR JNK PATHWAY JNK signaling in the CD4+ TCR pathway
0.1 1.0 SA PTEN PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.1 2.6 PID EPHRINB REV PATHWAY Ephrin B reverse signaling
0.1 4.5 PID TCR PATHWAY TCR signaling in naïve CD4+ T cells
0.1 1.2 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.1 0.6 SA FAS SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.1 1.7 PID IL8 CXCR2 PATHWAY IL8- and CXCR2-mediated signaling events
0.1 0.6 ST INTERFERON GAMMA PATHWAY Interferon gamma pathway.
0.1 2.3 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.1 0.8 PID PI3KCI PATHWAY Class I PI3K signaling events
0.1 1.7 PID TXA2PATHWAY Thromboxane A2 receptor signaling
0.1 1.3 PID ERBB1 INTERNALIZATION PATHWAY Internalization of ErbB1
0.0 1.5 PID BCR 5PATHWAY BCR signaling pathway
0.0 1.8 PID AR TF PATHWAY Regulation of Androgen receptor activity
0.0 0.2 PID CD8 TCR PATHWAY TCR signaling in naïve CD8+ T cells
0.0 0.9 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.0 0.0 PID CXCR3 PATHWAY CXCR3-mediated signaling events
0.0 0.1 PID TCR RAS PATHWAY Ras signaling in the CD4+ TCR pathway
0.0 0.2 ST PAC1 RECEPTOR PATHWAY PAC1 Receptor Pathway
0.0 0.8 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.0 0.1 PID RANBP2 PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.0 0.2 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
0.0 0.5 PID HIV NEF PATHWAY HIV-1 Nef: Negative effector of Fas and TNF-alpha
0.0 0.2 PID IL2 1PATHWAY IL2-mediated signaling events
0.0 0.3 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4
0.0 0.5 PID MYC PATHWAY C-MYC pathway
0.0 0.3 PID GMCSF PATHWAY GMCSF-mediated signaling events
0.0 0.0 SIG PIP3 SIGNALING IN B LYMPHOCYTES Genes related to PIP3 signaling in B lymphocytes
0.0 0.3 PID IL2 STAT5 PATHWAY IL2 signaling events mediated by STAT5
0.0 0.3 PID FCER1 PATHWAY Fc-epsilon receptor I signaling in mast cells
0.0 0.7 PID RAC1 PATHWAY RAC1 signaling pathway
0.0 0.1 PID CD40 PATHWAY CD40/CD40L signaling
0.0 0.2 PID P38 ALPHA BETA PATHWAY Regulation of p38-alpha and p38-beta
0.0 0.3 PID IFNG PATHWAY IFN-gamma pathway
0.0 0.0 ST DIFFERENTIATION PATHWAY IN PC12 CELLS Differentiation Pathway in PC12 Cells; this is a specific case of PAC1 Receptor Pathway.
0.0 0.0 ST GA12 PATHWAY G alpha 12 Pathway
0.0 0.1 PID THROMBIN PAR4 PATHWAY PAR4-mediated thrombin signaling events
0.0 0.4 PID IL12 2PATHWAY IL12-mediated signaling events
0.0 0.4 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.0 0.2 PID BETA CATENIN DEG PATHWAY Degradation of beta catenin
0.0 0.3 PID RAS PATHWAY Regulation of Ras family activation
0.0 0.2 ST PHOSPHOINOSITIDE 3 KINASE PATHWAY PI3K Pathway
0.0 0.2 PID WNT NONCANONICAL PATHWAY Noncanonical Wnt signaling pathway
0.0 0.2 PID LPA4 PATHWAY LPA4-mediated signaling events
0.0 0.3 PID ARF6 PATHWAY Arf6 signaling events
0.0 0.2 PID NFAT 3PATHWAY Role of Calcineurin-dependent NFAT signaling in lymphocytes
0.0 0.1 PID NFKAPPAB CANONICAL PATHWAY Canonical NF-kappaB pathway
0.0 0.1 ST TUMOR NECROSIS FACTOR PATHWAY Tumor Necrosis Factor Pathway.
0.0 0.1 SA G1 AND S PHASES Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition.
0.0 0.0 PID ARF6 DOWNSTREAM PATHWAY Arf6 downstream pathway
0.0 0.5 PID P53 REGULATION PATHWAY p53 pathway
0.0 0.0 PID EPO PATHWAY EPO signaling pathway
0.0 0.4 PID IL4 2PATHWAY IL4-mediated signaling events
0.0 0.1 PID THROMBIN PAR1 PATHWAY PAR1-mediated thrombin signaling events
0.0 0.4 PID AURORA B PATHWAY Aurora B signaling
0.0 0.1 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.0 0.0 ST JAK STAT PATHWAY Jak-STAT Pathway
0.0 0.3 PID CONE PATHWAY Visual signal transduction: Cones
0.0 0.2 PID INTEGRIN A4B1 PATHWAY Alpha4 beta1 integrin signaling events
0.0 0.4 PID LKB1 PATHWAY LKB1 signaling events
0.0 0.1 PID P38 ALPHA BETA DOWNSTREAM PATHWAY Signaling mediated by p38-alpha and p38-beta
0.0 0.0 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.0 0.1 SIG CD40PATHWAYMAP Genes related to CD40 signaling
0.0 0.1 PID HDAC CLASSII PATHWAY Signaling events mediated by HDAC Class II

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 REACTOME BINDING AND ENTRY OF HIV VIRION Genes involved in Binding and entry of HIV virion
0.2 2.1 REACTOME GENERATION OF SECOND MESSENGER MOLECULES Genes involved in Generation of second messenger molecules
0.1 1.0 REACTOME CD28 DEPENDENT VAV1 PATHWAY Genes involved in CD28 dependent Vav1 pathway
0.1 1.6 REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.1 2.5 REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.1 0.2 REACTOME AUTODEGRADATION OF THE E3 UBIQUITIN LIGASE COP1 Genes involved in Autodegradation of the E3 ubiquitin ligase COP1
0.1 1.5 REACTOME N GLYCAN ANTENNAE ELONGATION IN THE MEDIAL TRANS GOLGI Genes involved in N-glycan antennae elongation in the medial/trans-Golgi
0.1 0.6 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
0.1 1.3 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.1 0.1 REACTOME ENDOSOMAL VACUOLAR PATHWAY Genes involved in Endosomal/Vacuolar pathway
0.1 0.9 REACTOME CTLA4 INHIBITORY SIGNALING Genes involved in CTLA4 inhibitory signaling
0.1 0.7 REACTOME REGULATION OF IFNG SIGNALING Genes involved in Regulation of IFNG signaling
0.1 1.5 REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE Genes involved in Synthesis of PIPs at the plasma membrane
0.1 0.4 REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.1 0.8 REACTOME COSTIMULATION BY THE CD28 FAMILY Genes involved in Costimulation by the CD28 family
0.1 1.1 REACTOME THE ROLE OF NEF IN HIV1 REPLICATION AND DISEASE PATHOGENESIS Genes involved in The role of Nef in HIV-1 replication and disease pathogenesis
0.1 0.8 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.0 0.4 REACTOME RAF MAP KINASE CASCADE Genes involved in RAF/MAP kinase cascade
0.0 0.1 REACTOME REGULATION OF SIGNALING BY CBL Genes involved in Regulation of signaling by CBL
0.0 0.5 REACTOME GRB2 SOS PROVIDES LINKAGE TO MAPK SIGNALING FOR INTERGRINS Genes involved in GRB2:SOS provides linkage to MAPK signaling for Intergrins
0.0 1.3 REACTOME INTERFERON GAMMA SIGNALING Genes involved in Interferon gamma signaling
0.0 0.4 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.0 0.7 REACTOME CHONDROITIN SULFATE BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
0.0 2.0 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0 0.5 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.0 0.5 REACTOME IL RECEPTOR SHC SIGNALING Genes involved in Interleukin receptor SHC signaling
0.0 1.0 REACTOME REGULATION OF BETA CELL DEVELOPMENT Genes involved in Regulation of beta-cell development
0.0 0.3 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
0.0 0.1 REACTOME IL 3 5 AND GM CSF SIGNALING Genes involved in Interleukin-3, 5 and GM-CSF signaling
0.0 0.2 REACTOME IRAK1 RECRUITS IKK COMPLEX Genes involved in IRAK1 recruits IKK complex
0.0 0.7 REACTOME POST NMDA RECEPTOR ACTIVATION EVENTS Genes involved in Post NMDA receptor activation events
0.0 0.3 REACTOME DOWNSTREAM TCR SIGNALING Genes involved in Downstream TCR signaling
0.0 0.1 REACTOME SPRY REGULATION OF FGF SIGNALING Genes involved in Spry regulation of FGF signaling
0.0 0.6 REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.0 0.2 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0 0.4 REACTOME ASSOCIATION OF LICENSING FACTORS WITH THE PRE REPLICATIVE COMPLEX Genes involved in Association of licensing factors with the pre-replicative complex
0.0 0.2 REACTOME PKA MEDIATED PHOSPHORYLATION OF CREB Genes involved in PKA-mediated phosphorylation of CREB
0.0 0.1 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.0 0.6 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.0 0.4 REACTOME CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
0.0 0.3 REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING Genes involved in Formation of ATP by chemiosmotic coupling
0.0 0.5 REACTOME PRE NOTCH TRANSCRIPTION AND TRANSLATION Genes involved in Pre-NOTCH Transcription and Translation
0.0 0.4 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.0 0.5 REACTOME NOD1 2 SIGNALING PATHWAY Genes involved in NOD1/2 Signaling Pathway
0.0 0.7 REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.0 0.0 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION Genes involved in TRAF6 mediated IRF7 activation
0.0 0.2 REACTOME ASSEMBLY OF THE PRE REPLICATIVE COMPLEX Genes involved in Assembly of the pre-replicative complex
0.0 0.0 REACTOME SHC MEDIATED SIGNALLING Genes involved in SHC-mediated signalling
0.0 0.4 REACTOME NUCLEOTIDE LIKE PURINERGIC RECEPTORS Genes involved in Nucleotide-like (purinergic) receptors
0.0 0.0 REACTOME GPVI MEDIATED ACTIVATION CASCADE Genes involved in GPVI-mediated activation cascade
0.0 0.0 REACTOME SHC RELATED EVENTS Genes involved in SHC-related events
0.0 0.1 REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.0 0.2 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.0 0.7 REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.0 0.3 REACTOME TRANSPORT TO THE GOLGI AND SUBSEQUENT MODIFICATION Genes involved in Transport to the Golgi and subsequent modification
0.0 0.4 REACTOME KERATAN SULFATE BIOSYNTHESIS Genes involved in Keratan sulfate biosynthesis
0.0 0.8 REACTOME GLYCOSPHINGOLIPID METABOLISM Genes involved in Glycosphingolipid metabolism
0.0 1.0 REACTOME ACTIVATION OF NF KAPPAB IN B CELLS Genes involved in Activation of NF-kappaB in B Cells
0.0 0.2 REACTOME HIGHLY CALCIUM PERMEABLE POSTSYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Highly calcium permeable postsynaptic nicotinic acetylcholine receptors
0.0 0.4 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.0 0.0 REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.0 0.1 REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS Genes involved in Membrane binding and targetting of GAG proteins
0.0 0.2 REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION Genes involved in GABA synthesis, release, reuptake and degradation
0.0 0.3 REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.0 0.5 REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS Genes involved in Apoptotic cleavage of cellular proteins
0.0 0.2 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.0 0.3 REACTOME INTRINSIC PATHWAY Genes involved in Intrinsic Pathway
0.0 0.2 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.0 0.2 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.0 1.1 REACTOME RESPIRATORY ELECTRON TRANSPORT ATP SYNTHESIS BY CHEMIOSMOTIC COUPLING AND HEAT PRODUCTION BY UNCOUPLING PROTEINS Genes involved in Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins.
0.0 0.2 REACTOME TRAF6 MEDIATED NFKB ACTIVATION Genes involved in TRAF6 mediated NF-kB activation
0.0 0.1 REACTOME DSCAM INTERACTIONS Genes involved in DSCAM interactions
0.0 0.2 REACTOME TRANSPORT OF ORGANIC ANIONS Genes involved in Transport of organic anions
0.0 0.2 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.0 0.1 REACTOME SIGNALING BY WNT Genes involved in Signaling by Wnt
0.0 0.2 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.0 0.7 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.0 0.2 REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.0 0.2 REACTOME NUCLEOTIDE BINDING DOMAIN LEUCINE RICH REPEAT CONTAINING RECEPTOR NLR SIGNALING PATHWAYS Genes involved in Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways
0.0 0.2 REACTOME AMINE DERIVED HORMONES Genes involved in Amine-derived hormones
0.0 0.2 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.0 0.0 REACTOME PROSTACYCLIN SIGNALLING THROUGH PROSTACYCLIN RECEPTOR Genes involved in Prostacyclin signalling through prostacyclin receptor
0.0 0.1 REACTOME AKT PHOSPHORYLATES TARGETS IN THE CYTOSOL Genes involved in AKT phosphorylates targets in the cytosol
0.0 0.0 REACTOME LYSOSOME VESICLE BIOGENESIS Genes involved in Lysosome Vesicle Biogenesis
0.0 0.2 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GLP1 Genes involved in Synthesis, Secretion, and Inactivation of Glucagon-like Peptide-1 (GLP-1)
0.0 0.0 REACTOME INTERACTIONS OF VPR WITH HOST CELLULAR PROTEINS Genes involved in Interactions of Vpr with host cellular proteins
0.0 0.2 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.0 0.6 REACTOME METABOLISM OF NON CODING RNA Genes involved in Metabolism of non-coding RNA
0.0 0.5 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.0 0.0 REACTOME MRNA CAPPING Genes involved in mRNA Capping
0.0 0.2 REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.0 0.1 REACTOME G PROTEIN ACTIVATION Genes involved in G-protein activation
0.0 0.1 REACTOME PRE NOTCH PROCESSING IN GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.0 0.0 REACTOME S PHASE Genes involved in S Phase
0.0 0.3 REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES Genes involved in Antiviral mechanism by IFN-stimulated genes
0.0 0.0 REACTOME CDK MEDIATED PHOSPHORYLATION AND REMOVAL OF CDC6 Genes involved in CDK-mediated phosphorylation and removal of Cdc6
0.0 0.1 REACTOME ABACAVIR TRANSPORT AND METABOLISM Genes involved in Abacavir transport and metabolism
0.0 0.1 REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Glutamate Neurotransmitter Release Cycle
0.0 1.1 REACTOME MRNA SPLICING Genes involved in mRNA Splicing
0.0 0.0 REACTOME HS GAG DEGRADATION Genes involved in HS-GAG degradation
0.0 0.2 REACTOME METAL ION SLC TRANSPORTERS Genes involved in Metal ion SLC transporters
0.0 0.1 REACTOME ALPHA LINOLENIC ACID ALA METABOLISM Genes involved in alpha-linolenic acid (ALA) metabolism
0.0 0.1 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.0 0.1 REACTOME ER PHAGOSOME PATHWAY Genes involved in ER-Phagosome pathway
0.0 0.1 REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.0 0.0 REACTOME INTEGRATION OF PROVIRUS Genes involved in Integration of provirus
0.0 0.0 REACTOME REGULATION OF IFNA SIGNALING Genes involved in Regulation of IFNA signaling
0.0 0.0 REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
0.0 0.1 REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.0 0.1 REACTOME COPI MEDIATED TRANSPORT Genes involved in COPI Mediated Transport
0.0 1.0 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.0 0.0 REACTOME PROCESSING OF CAPPED INTRON CONTAINING PRE MRNA Genes involved in Processing of Capped Intron-Containing Pre-mRNA
0.0 0.7 REACTOME MEIOTIC SYNAPSIS Genes involved in Meiotic Synapsis