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ENCODE: H3K4me1 ChIP-Seq of primary human cells

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Results for PBX1

Z-value: 1.36

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Transcription factors associated with PBX1

Gene Symbol	Gene ID	Gene Info
PBX1 Ensembl NCBI GeneCards UniProt	ENSG00000185630.14	PBX homeobox 1

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE	Gene	Distance	Association probability	Pearson corr. coef.	P-value	Plot
chr1_164580979_164581130	PBX1	14189	0.217248	-0.92	3.6e-04	Click!
chr1_164741025_164741240	PBX1	1017	0.518282	-0.88	1.7e-03	Click!
chr1_164742488_164742639	PBX1	414	0.778690	-0.82	6.9e-03	Click!
chr1_164571766_164571917	PBX1	23402	0.204453	-0.81	8.0e-03	Click!
chr1_164733455_164733606	PBX1	8619	0.196572	-0.79	1.2e-02	Click!

Activity of the PBX1 motif across conditions

Conditions sorted by the z-value of the PBX1 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE)	Target Score	Top associated gene	Gene Info	Distance of CRE to TSS	CRE/Gene association probability
chr17_30902769_30903098	0.71	RP11-466A19.5		45866	0.1
chr1_65342372_65342702	0.68	JAK1	Janus kinase 1	89650	0.08
chr3_107695991_107696269	0.64	CD47	CD47 molecule	81078	0.11
chr7_50358033_50358422	0.61	IKZF1	IKAROS family zinc finger 1 (Ikaros)	9018	0.29
chr2_158276348_158276584	0.57	CYTIP	cytohesin 1 interacting protein	19460	0.2
chr6_106737124_106737275	0.56	ENSG00000244710	.	5613	0.2
chr14_98657577_98657728	0.52	ENSG00000222066	.	140435	0.05
chr1_26696466_26696677	0.51	ZNF683	zinc finger protein 683	665	0.58
chr12_69034261_69034415	0.50	ENSG00000206650	.	13183	0.19
chr11_128436850_128437001	0.48	ETS1	v-ets avian erythroblastosis virus E26 oncogene homolog 1	20528	0.21
chr2_99084461_99084735	0.47	INPP4A	inositol polyphosphate-4-phosphatase, type I, 107kDa	23185	0.21
chr17_38763766_38763917	0.46	SMARCE1	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 1	24701	0.13
chr6_159434242_159434587	0.45	RP1-111C20.4		12564	0.17
chr14_91814952_91815599	0.45	ENSG00000265856	.	15218	0.22
chr9_37391017_37391168	0.44	GRHPR	glyoxylate reductase/hydroxypyruvate reductase	31571	0.15
chr10_46053827_46054093	0.44	MARCH8	membrane-associated ring finger (C3HC4) 8, E3 ubiquitin protein ligase	23118	0.22
chr7_37349133_37349657	0.43	ELMO1	engulfment and cell motility 1	32972	0.18
chr9_101789958_101790159	0.43	TGFBR1	transforming growth factor, beta receptor 1	76262	0.09
chr1_169674701_169674897	0.43	SELL	selectin L	6040	0.21
chr1_42793424_42793575	0.43	FOXJ3	forkhead box J3	7137	0.2
chr2_204868825_204868976	0.43	ICOS	inducible T-cell co-stimulator	67397	0.13
chr6_24957255_24957453	0.43	FAM65B	family with sequence similarity 65, member B	21166	0.2
chr2_3246663_3247121	0.42	TSSC1-IT1	TSSC1 intronic transcript 1 (non-protein coding)	58344	0.14
chr21_47972699_47973025	0.42	ENSG00000272283	.	17153	0.17
chr14_89722620_89722771	0.42	FOXN3	forkhead box N3	75607	0.1
chr6_143229651_143229867	0.41	HIVEP2	human immunodeficiency virus type I enhancer binding protein 2	36579	0.2
chr5_151907032_151907224	0.40	NMUR2	neuromedin U receptor 2	122288	0.07
chr21_19148494_19148866	0.40	AL109761.5		17125	0.22
chr5_156999365_156999526	0.40	ADAM19	ADAM metallopeptidase domain 19	3304	0.19
chr7_50306943_50307629	0.39	IKZF1	IKAROS family zinc finger 1 (Ikaros)	37038	0.2
chr2_8625925_8626222	0.39	AC011747.7		189823	0.03
chr9_36145556_36145707	0.39	GLIPR2	GLI pathogenesis-related 2	8889	0.18
chr8_82104288_82104439	0.39	PAG1	phosphoprotein associated with glycosphingolipid microdomains 1	80060	0.09
chr16_57021435_57021712	0.39	NLRC5	NLR family, CARD domain containing 5	1837	0.25
chr14_78224263_78224414	0.39	C14orf178	chromosome 14 open reading frame 178	2835	0.18
chr10_3915023_3915255	0.39	KLF6	Kruppel-like factor 6	87666	0.09
chr2_235204073_235204224	0.39	ARL4C	ADP-ribosylation factor-like 4C	201096	0.03
chr17_40423553_40423822	0.38	AC003104.1		298	0.83
chr16_3623403_3623748	0.38	NLRC3	NLR family, CARD domain containing 3	3817	0.17
chr17_63026003_63026264	0.38	RP11-583F2.5		21894	0.15
chr3_98275754_98275968	0.38	GPR15	G protein-coupled receptor 15	25118	0.13
chr17_66343606_66343891	0.38	ARSG	arylsulfatase G	56089	0.1
chr7_36325933_36326467	0.37	EEPD1	endonuclease/exonuclease/phosphatase family domain containing 1	10553	0.18
chr3_43372779_43372930	0.37	RP11-188P20.3		16281	0.16
chr7_21474691_21474842	0.37	SP4	Sp4 transcription factor	7105	0.2
chr2_148388820_148389572	0.37	ENSG00000253083	.	81927	0.1
chr1_112053499_112053798	0.37	ADORA3	adenosine A3 receptor	7266	0.13
chr8_22967185_22967337	0.37	TNFRSF10C	tumor necrosis factor receptor superfamily, member 10c, decoy without an intracellular domain	6827	0.14
chr19_1935619_1935770	0.36	CSNK1G2	casein kinase 1, gamma 2	5494	0.11
chr9_120588985_120589386	0.36	ENSG00000251847	.	95436	0.08
chr5_7778754_7778905	0.36	RP11-711G10.1		28950	0.2
chr9_100177542_100177693	0.36	TDRD7	tudor domain containing 7	3241	0.29
chr5_55152116_55152357	0.36	IL31RA	interleukin 31 receptor A	2878	0.28
chr18_3059365_3059574	0.36	ENSG00000252258	.	33905	0.13
chr16_46836785_46836936	0.36	C16orf87	chromosome 16 open reading frame 87	28120	0.17
chr5_79486493_79486756	0.36	ENSG00000239159	.	48784	0.12
chr19_18655304_18655455	0.35	FKBP8	FK506 binding protein 8, 38kDa	492	0.6
chr9_92083234_92083501	0.35	SEMA4D	sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D	11438	0.23
chr7_114616275_114616426	0.35	MDFIC	MyoD family inhibitor domain containing	42426	0.21
chr19_910573_910814	0.35	R3HDM4	R3H domain containing 4	2538	0.12
chr11_17308544_17308695	0.35	NUCB2	nucleobindin 2	8252	0.21
chr3_71507289_71507548	0.35	ENSG00000221264	.	83822	0.09
chr2_43402102_43402312	0.34	ZFP36L2	ZFP36 ring finger protein-like 2	51541	0.14
chr5_39175400_39175649	0.34	FYB	FYN binding protein	27605	0.22
chr3_33065058_33065320	0.34	CCR4	chemokine (C-C motif) receptor 4	72123	0.08
chr3_186278072_186278223	0.34	TBCCD1	TBCC domain containing 1	3987	0.17
chr4_40231477_40231628	0.34	RHOH	ras homolog family member H	29588	0.18
chr7_21397453_21397701	0.34	ENSG00000195024	.	23404	0.21
chr1_62249924_62250078	0.34	ENSG00000200575	.	32090	0.16
chr10_26752397_26752592	0.34	APBB1IP	amyloid beta (A4) precursor protein-binding, family B, member 1 interacting protein	25140	0.22
chr1_9713515_9713810	0.34	C1orf200	chromosome 1 open reading frame 200	982	0.47
chr6_24894743_24895047	0.34	FAM65B	family with sequence similarity 65, member B	16300	0.2
chr2_99326136_99326596	0.34	MGAT4A	mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme A	16793	0.22
chr1_108446611_108446981	0.34	VAV3-AS1	VAV3 antisense RNA 1	60269	0.13
chr9_31347928_31348079	0.33	ENSG00000211510	.	573777	0.0
chr16_53471043_53471490	0.33	RBL2	retinoblastoma-like 2 (p130)	1735	0.31
chrX_44105289_44105582	0.33	EFHC2	EF-hand domain (C-terminal) containing 2	97483	0.08
chr18_60198457_60198694	0.33	ZCCHC2	zinc finger, CCHC domain containing 2	7723	0.28
chr11_128495468_128495740	0.33	ETS1	v-ets avian erythroblastosis virus E26 oncogene homolog 1	38151	0.15
chr7_76984643_76984884	0.33	GSAP	gamma-secretase activating protein	25079	0.21
chr20_37432775_37433181	0.33	PPP1R16B	protein phosphatase 1, regulatory subunit 16B	1370	0.43
chr2_182128679_182128830	0.33	ENSG00000266705	.	41625	0.21
chr2_145215910_145216141	0.33	ZEB2	zinc finger E-box binding homeobox 2	27888	0.23
chr16_79126975_79127217	0.33	RP11-556H2.3		3149	0.25
chr5_100234402_100234890	0.33	ST8SIA4	ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4	4272	0.34
chr19_3136880_3137097	0.33	GNA15	guanine nucleotide binding protein (G protein), alpha 15 (Gq class)	797	0.47
chr14_71464254_71464520	0.33	PCNX	pecanex homolog (Drosophila)	15361	0.29
chr17_33857619_33857982	0.33	SLFN12L	schlafen family member 12-like	7080	0.12
chr20_21527565_21527785	0.33	NKX2-2	NK2 homeobox 2	33011	0.18
chr16_79652368_79652707	0.33	MAF	v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog	17926	0.26
chr9_92109429_92109613	0.33	SEMA4D	sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D	2826	0.29
chr17_29700013_29700185	0.32	NF1	neurofibromin 1	14533	0.14
chr9_126630414_126630599	0.32	DENND1A	DENN/MADD domain containing 1A	61880	0.12
chr15_55514570_55514956	0.32	RSL24D1	ribosomal L24 domain containing 1	25498	0.18
chr22_42651907_42652058	0.32	TCF20	transcription factor 20 (AR1)	40534	0.14
chr22_30583521_30583829	0.32	RP3-438O4.4		19423	0.13
chr6_36516425_36516576	0.32	STK38	serine/threonine kinase 38	1253	0.39
chrX_78424933_78425109	0.32	GPR174	G protein-coupled receptor 174	1448	0.59
chr5_75825749_75825973	0.32	IQGAP2	IQ motif containing GTPase activating protein 2	17373	0.24
chr8_117878667_117878892	0.32	RAD21	RAD21 homolog (S. pombe)	7820	0.17
chr17_76766802_76766972	0.32	CYTH1	cytohesin 1	11467	0.18
chr3_71750685_71750964	0.32	EIF4E3	eukaryotic translation initiation factor 4E family member 3	23702	0.2
chr14_91872440_91872844	0.32	CCDC88C	coiled-coil domain containing 88C	11048	0.24
chr8_19331940_19332091	0.32	CSGALNACT1	chondroitin sulfate N-acetylgalactosaminyltransferase 1	127361	0.06
chr3_67729128_67729286	0.31	SUCLG2	succinate-CoA ligase, GDP-forming, beta subunit	24169	0.28
chr12_113527618_113527818	0.31	DTX1	deltex homolog 1 (Drosophila)	32223	0.11
chr1_24840661_24840812	0.31	RCAN3	RCAN family member 3	74	0.97
chr10_105671429_105671739	0.31	OBFC1	oligonucleotide/oligosaccharide-binding fold containing 1	5843	0.19
chrX_135742690_135742856	0.31	CD40LG	CD40 ligand	12387	0.17
chr1_117528994_117529403	0.31	CD101	CD101 molecule	15184	0.16
chr2_12850330_12850505	0.31	TRIB2	tribbles pseudokinase 2	6598	0.28
chr7_127496048_127496199	0.31	SND1	staphylococcal nuclease and tudor domain containing 1	31842	0.22
chr8_67404169_67404359	0.31	C8orf46	chromosome 8 open reading frame 46	1179	0.48
chr20_39775264_39775450	0.31	RP1-1J6.2		8714	0.2
chr3_20147752_20147943	0.31	ENSG00000266745	.	31210	0.16
chr1_101707393_101707553	0.31	RP4-575N6.5		1241	0.4
chr9_71399988_71400193	0.31	FAM122A	family with sequence similarity 122A	5126	0.25
chr1_100847278_100847500	0.31	ENSG00000216067	.	3058	0.27
chr1_40778667_40778833	0.31	COL9A2	collagen, type IX, alpha 2	3612	0.2
chr16_29235615_29235838	0.31	RP11-231C14.6		87945	0.06
chr2_85085633_85085887	0.31	TRABD2A	TraB domain containing 2A	22446	0.18
chr18_29620502_29620880	0.30	ENSG00000265063	.	20261	0.13
chr8_128182820_128182971	0.30	POU5F1B	POU class 5 homeobox 1B	243640	0.02
chr19_30460699_30460945	0.30	URI1	URI1, prefoldin-like chaperone	1178	0.65
chr19_381111_381262	0.30	THEG	theg spermatid protein	5173	0.15
chr11_35147581_35147732	0.30	AL356215.1		2559	0.25
chr1_28582972_28583123	0.30	SESN2	sestrin 2	2991	0.16
chr15_77304869_77305028	0.30	PSTPIP1	proline-serine-threonine phosphatase interacting protein 1	3204	0.26
chrX_48791618_48791902	0.30	PIM2	pim-2 oncogene	15459	0.09
chr1_169558158_169558702	0.30	F5	coagulation factor V (proaccelerin, labile factor)	2604	0.31
chr13_41177729_41177880	0.30	FOXO1	forkhead box O1	62930	0.12
chr10_11183526_11183726	0.30	CELF2	CUGBP, Elav-like family member 2	23367	0.18
chr7_43874382_43874686	0.30	MRPS24	mitochondrial ribosomal protein S24	34622	0.13
chr4_153320237_153320432	0.30	FBXW7	F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase	12696	0.24
chr2_65469172_65469323	0.30	ACTR2	ARP2 actin-related protein 2 homolog (yeast)	14276	0.23
chr1_66805112_66805335	0.30	PDE4B	phosphodiesterase 4B, cAMP-specific	7351	0.32
chr7_21469720_21469989	0.30	SP4	Sp4 transcription factor	2193	0.3
chrX_19804751_19804902	0.30	SH3KBP1	SH3-domain kinase binding protein 1	13043	0.29
chr3_46390356_46390605	0.30	CCR2	chemokine (C-C motif) receptor 2	4745	0.2
chr17_76814852_76815192	0.30	USP36	ubiquitin specific peptidase 36	4309	0.2
chr2_204726088_204726239	0.30	CTLA4	cytotoxic T-lymphocyte-associated protein 4	6346	0.27
chr6_42540871_42541167	0.30	UBR2	ubiquitin protein ligase E3 component n-recognin 2	9219	0.22
chr2_42327539_42327704	0.29	PKDCC	protein kinase domain containing, cytoplasmic	52461	0.13
chr2_143943022_143943284	0.29	RP11-190J23.1		13412	0.27
chr21_36332815_36332966	0.29	RUNX1	runt-related transcription factor 1	70803	0.13
chr12_1813704_1813855	0.29	ADIPOR2	adiponectin receptor 2	13586	0.2
chr7_50350335_50350543	0.29	IKZF1	IKAROS family zinc finger 1 (Ikaros)	2121	0.44
chr18_46927885_46928119	0.29	DYM	dymeclin	22983	0.15
chr6_144740266_144740510	0.29	UTRN	utrophin	75151	0.11
chr17_8800034_8800185	0.29	PIK3R5	phosphoinositide-3-kinase, regulatory subunit 5	14715	0.2
chr10_22963946_22964164	0.29	PIP4K2A	phosphatidylinositol-5-phosphate 4-kinase, type II, alpha	38982	0.2
chr7_1087128_1087349	0.29	GPR146	G protein-coupled receptor 146	3026	0.13
chr2_8615480_8615853	0.29	AC011747.7		200230	0.03
chr2_198670473_198670941	0.29	PLCL1	phospholipase C-like 1	1281	0.51
chr11_18652208_18652359	0.29	SPTY2D1	SPT2, Suppressor of Ty, domain containing 1 (S. cerevisiae)	3757	0.19
chr11_128604204_128604783	0.29	FLI1	Fli-1 proto-oncogene, ETS transcription factor	30192	0.16
chr15_74756022_74756173	0.29	UBL7-AS1	UBL7 antisense RNA 1 (head to head)	2412	0.2
chr11_74986567_74986718	0.29	ARRB1	arrestin, beta 1	3101	0.18
chr10_3709420_3709846	0.29	RP11-184A2.3		83626	0.1
chr2_38898002_38898320	0.29	AC074366.3		402	0.84
chr1_100905257_100905795	0.29	RP5-837M10.4		46027	0.13
chr7_50350560_50351095	0.29	IKZF1	IKAROS family zinc finger 1 (Ikaros)	2509	0.41
chr3_27924725_27925089	0.28	EOMES	eomesodermin	160701	0.04
chr3_195314371_195314522	0.28	APOD	apolipoprotein D	3370	0.23
chr1_100868916_100869067	0.28	ENSG00000216067	.	24660	0.18
chr20_51738395_51738546	0.28	ENSG00000199218	.	24279	0.18
chr3_13055323_13055569	0.28	IQSEC1	IQ motif and Sec7 domain 1	26910	0.23
chr11_121237928_121238130	0.28	SC5D	sterol-C5-desaturase	74468	0.11
chr18_74832353_74832701	0.28	MBP	myelin basic protein	7141	0.31
chr4_89202595_89202746	0.28	PPM1K	protein phosphatase, Mg2+/Mn2+ dependent, 1K	2372	0.23
chr17_38779166_38779543	0.28	SMARCE1	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 1	9188	0.15
chr4_78726984_78727206	0.28	CNOT6L	CCR4-NOT transcription complex, subunit 6-like	13122	0.26
chr2_198071433_198071665	0.28	ANKRD44	ankyrin repeat domain 44	8787	0.21
chr2_225895173_225895367	0.28	DOCK10	dedicator of cytokinesis 10	11889	0.25
chr6_53296483_53296678	0.28	ENSG00000253010	.	16175	0.18
chrX_19762386_19762616	0.28	SH3KBP1	SH3-domain kinase binding protein 1	2028	0.47
chr5_75822469_75822680	0.28	IQGAP2	IQ motif containing GTPase activating protein 2	20660	0.23
chr9_91536946_91537097	0.28	C9orf47	chromosome 9 open reading frame 47	68757	0.11
chr17_30678180_30678332	0.28	ZNF207	zinc finger protein 207	329	0.74
chr5_110652187_110652338	0.28	CTC-499J9.1		13997	0.23
chr3_107781222_107781468	0.28	CD47	CD47 molecule	2966	0.4
chr17_37043988_37044139	0.28	LASP1	LIM and SH3 protein 1	13920	0.09
chr1_54945402_54945553	0.28	ENSG00000265404	.	24864	0.16
chr6_41115741_41115912	0.28	TREML1	triggering receptor expressed on myeloid cells-like 1	6244	0.14
chr17_8858301_8858611	0.28	PIK3R5	phosphoinositide-3-kinase, regulatory subunit 5	10568	0.24
chr18_29623121_29623509	0.28	ENSG00000265063	.	17637	0.13
chr4_38244417_38244568	0.28	ENSG00000221495	.	4258	0.36
chr11_122571839_122572000	0.27	ENSG00000239079	.	25100	0.2
chr10_7554785_7554936	0.27	RP11-385N23.1		20309	0.21
chr2_198081838_198081989	0.27	ANKRD44	ankyrin repeat domain 44	19151	0.19
chr2_136872566_136873100	0.27	CXCR4	chemokine (C-X-C motif) receptor 4	980	0.68
chr22_30712298_30712449	0.27	TBC1D10A	TBC1 domain family, member 10A	8494	0.1
chr8_81955099_81955250	0.27	PAG1	phosphoprotein associated with glycosphingolipid microdomains 1	69129	0.12
chr1_169671553_169671957	0.27	SELL	selectin L	9084	0.2
chr10_87373902_87374053	0.27	RP11-93H12.2		8827	0.23
chr2_204725673_204726054	0.27	CTLA4	cytotoxic T-lymphocyte-associated protein 4	6646	0.27
chr12_68594355_68594506	0.27	IL26	interleukin 26	25171	0.19
chr13_94983282_94983449	0.27	ENSG00000212057	.	134279	0.05
chr17_33861876_33862027	0.27	SLFN12L	schlafen family member 12-like	2929	0.15
chr19_42705324_42705478	0.27	ENSG00000265122	.	8171	0.09

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of PBX1

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View png image

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	0.8	GO:0002710	negative regulation of T cell mediated immunity(GO:0002710)
0.2	0.6	GO:0019276	UDP-N-acetylgalactosamine metabolic process(GO:0019276)
0.2	0.8	GO:0030854	positive regulation of granulocyte differentiation(GO:0030854)
0.2	0.8	GO:0033152	immunoglobulin V(D)J recombination(GO:0033152)
0.2	0.2	GO:0002326	B cell lineage commitment(GO:0002326)
0.2	0.7	GO:0046642	negative regulation of alpha-beta T cell proliferation(GO:0046642)
0.2	0.5	GO:0035405	histone-threonine phosphorylation(GO:0035405)
0.2	0.7	GO:0045589	regulation of regulatory T cell differentiation(GO:0045589)
0.2	1.3	GO:0006491	N-glycan processing(GO:0006491)
0.1	0.3	GO:0002664	T cell tolerance induction(GO:0002517) regulation of T cell tolerance induction(GO:0002664) positive regulation of T cell tolerance induction(GO:0002666)
0.1	0.4	GO:0045722	positive regulation of gluconeogenesis(GO:0045722)
0.1	0.4	GO:0070779	D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
0.1	0.5	GO:0032237	activation of store-operated calcium channel activity(GO:0032237) regulation of store-operated calcium channel activity(GO:1901339) positive regulation of store-operated calcium channel activity(GO:1901341)
0.1	0.9	GO:0006198	cAMP catabolic process(GO:0006198)
0.1	0.4	GO:0043320	natural killer cell activation involved in immune response(GO:0002323) natural killer cell degranulation(GO:0043320)
0.1	0.4	GO:0010459	negative regulation of heart rate(GO:0010459)
0.1	0.2	GO:0045341	MHC class I biosynthetic process(GO:0045341) regulation of MHC class I biosynthetic process(GO:0045343)
0.1	0.3	GO:0010957	negative regulation of calcidiol 1-monooxygenase activity(GO:0010956) negative regulation of vitamin D biosynthetic process(GO:0010957) negative regulation of vitamin metabolic process(GO:0046137)
0.1	0.3	GO:0010447	response to acidic pH(GO:0010447)
0.1	0.8	GO:0051489	regulation of filopodium assembly(GO:0051489)
0.1	0.5	GO:0045348	positive regulation of MHC class II biosynthetic process(GO:0045348)
0.1	0.3	GO:0045066	regulatory T cell differentiation(GO:0045066)
0.1	0.3	GO:0010572	positive regulation of platelet activation(GO:0010572)
0.1	0.7	GO:0007172	signal complex assembly(GO:0007172)
0.1	0.3	GO:0031580	membrane raft polarization(GO:0001766) membrane raft distribution(GO:0031580) membrane raft localization(GO:0051665)
0.1	0.2	GO:0002313	mature B cell differentiation involved in immune response(GO:0002313)
0.1	0.2	GO:0002693	regulation of cellular extravasation(GO:0002691) positive regulation of cellular extravasation(GO:0002693)
0.1	0.2	GO:0001831	trophectodermal cellular morphogenesis(GO:0001831)
0.1	0.2	GO:0010882	regulation of cardiac muscle contraction by calcium ion signaling(GO:0010882)
0.1	0.2	GO:0042091	interleukin-10 biosynthetic process(GO:0042091) regulation of interleukin-10 biosynthetic process(GO:0045074)
0.1	0.2	GO:0072600	protein targeting to Golgi(GO:0000042) establishment of protein localization to Golgi(GO:0072600)
0.1	0.4	GO:0042989	sequestering of actin monomers(GO:0042989)
0.1	0.1	GO:0030223	neutrophil differentiation(GO:0030223)
0.1	0.2	GO:0018076	N-terminal peptidyl-lysine acetylation(GO:0018076)
0.1	0.2	GO:0050862	positive regulation of T cell receptor signaling pathway(GO:0050862)
0.1	0.2	GO:0002523	leukocyte migration involved in inflammatory response(GO:0002523)
0.1	0.4	GO:0032875	regulation of DNA endoreduplication(GO:0032875) negative regulation of DNA endoreduplication(GO:0032876) DNA endoreduplication(GO:0042023)
0.1	1.8	GO:0050690	regulation of defense response to virus by virus(GO:0050690)
0.1	0.2	GO:0002282	microglial cell activation involved in immune response(GO:0002282)
0.1	0.1	GO:0070682	proteasome regulatory particle assembly(GO:0070682)
0.1	0.1	GO:0061154	endothelial tube morphogenesis(GO:0061154)
0.1	0.5	GO:0050858	negative regulation of antigen receptor-mediated signaling pathway(GO:0050858) negative regulation of T cell receptor signaling pathway(GO:0050860)
0.1	0.2	GO:0002085	inhibition of neuroepithelial cell differentiation(GO:0002085)
0.1	0.3	GO:1904376	negative regulation of establishment of protein localization to plasma membrane(GO:0090005) negative regulation of protein localization to plasma membrane(GO:1903077) negative regulation of protein localization to cell periphery(GO:1904376)
0.1	0.4	GO:0060123	regulation of growth hormone secretion(GO:0060123)
0.1	0.3	GO:0040023	establishment of nucleus localization(GO:0040023)
0.1	0.2	GO:0090292	nuclear matrix organization(GO:0043578) nuclear matrix anchoring at nuclear membrane(GO:0090292)
0.1	0.1	GO:0002495	antigen processing and presentation of peptide antigen via MHC class II(GO:0002495)
0.1	0.1	GO:0034139	regulation of toll-like receptor 3 signaling pathway(GO:0034139)
0.1	0.2	GO:0006855	drug transmembrane transport(GO:0006855)
0.1	0.1	GO:0006269	DNA replication, synthesis of RNA primer(GO:0006269)
0.1	0.4	GO:0008653	lipopolysaccharide metabolic process(GO:0008653)
0.1	0.7	GO:0044409	entry into host cell(GO:0030260) entry into host(GO:0044409) entry into cell of other organism involved in symbiotic interaction(GO:0051806) entry into other organism involved in symbiotic interaction(GO:0051828)
0.1	0.2	GO:0030644	cellular chloride ion homeostasis(GO:0030644) chloride ion homeostasis(GO:0055064)
0.1	0.2	GO:0010867	positive regulation of triglyceride biosynthetic process(GO:0010867)
0.1	0.1	GO:0097709	connective tissue replacement involved in inflammatory response wound healing(GO:0002248) connective tissue replacement(GO:0097709)
0.1	0.1	GO:0042536	negative regulation of tumor necrosis factor biosynthetic process(GO:0042536)
0.1	0.2	GO:0006089	lactate metabolic process(GO:0006089)
0.1	1.2	GO:0045576	mast cell activation(GO:0045576)
0.1	0.5	GO:0030206	chondroitin sulfate biosynthetic process(GO:0030206)
0.1	0.2	GO:0015917	aminophospholipid transport(GO:0015917)
0.1	0.1	GO:0035520	monoubiquitinated protein deubiquitination(GO:0035520)
0.1	0.2	GO:0030187	melatonin metabolic process(GO:0030186) melatonin biosynthetic process(GO:0030187)
0.1	0.3	GO:0042508	tyrosine phosphorylation of Stat1 protein(GO:0042508)
0.1	0.1	GO:0001866	NK T cell proliferation(GO:0001866)
0.1	0.1	GO:0033622	integrin activation(GO:0033622)
0.1	0.6	GO:0043368	positive T cell selection(GO:0043368)
0.1	0.2	GO:0045349	interferon-alpha biosynthetic process(GO:0045349) regulation of interferon-alpha biosynthetic process(GO:0045354) positive regulation of interferon-alpha biosynthetic process(GO:0045356)
0.1	0.2	GO:0035751	lysosomal lumen acidification(GO:0007042) regulation of lysosomal lumen pH(GO:0035751)
0.1	0.2	GO:0006689	ganglioside catabolic process(GO:0006689)
0.1	0.1	GO:0060766	negative regulation of androgen receptor signaling pathway(GO:0060766)
0.1	0.1	GO:0002890	negative regulation of B cell mediated immunity(GO:0002713) negative regulation of immunoglobulin mediated immune response(GO:0002890)
0.1	0.3	GO:0000281	mitotic cytokinesis(GO:0000281)
0.1	0.6	GO:0000303	response to superoxide(GO:0000303)
0.1	0.1	GO:0031936	negative regulation of chromatin silencing(GO:0031936)
0.1	0.2	GO:0003351	epithelial cilium movement(GO:0003351) epithelial cilium movement involved in determination of left/right asymmetry(GO:0060287)
0.1	0.2	GO:0071168	protein localization to chromatin(GO:0071168)
0.1	0.3	GO:0045003	DNA recombinase assembly(GO:0000730) double-strand break repair via synthesis-dependent strand annealing(GO:0045003)
0.1	0.3	GO:1901797	negative regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043518) negative regulation of signal transduction by p53 class mediator(GO:1901797)
0.1	0.2	GO:0032733	positive regulation of interleukin-10 production(GO:0032733)
0.1	0.2	GO:0070670	response to interleukin-4(GO:0070670)
0.1	0.3	GO:0007256	activation of JNKK activity(GO:0007256)
0.0	0.1	GO:0007207	phospholipase C-activating G-protein coupled acetylcholine receptor signaling pathway(GO:0007207)
0.0	0.2	GO:0002507	tolerance induction(GO:0002507)
0.0	0.3	GO:0048013	ephrin receptor signaling pathway(GO:0048013)
0.0	0.3	GO:0043550	regulation of lipid kinase activity(GO:0043550)
0.0	0.1	GO:0043653	mitochondrial fragmentation involved in apoptotic process(GO:0043653)
0.0	1.0	GO:0046677	response to antibiotic(GO:0046677)
0.0	0.1	GO:0006922	obsolete cleavage of lamin involved in execution phase of apoptosis(GO:0006922)
0.0	0.0	GO:0003402	planar cell polarity pathway involved in axis elongation(GO:0003402)
0.0	0.4	GO:0000381	regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.0	0.1	GO:0051458	corticotropin secretion(GO:0051458) regulation of corticotropin secretion(GO:0051459) positive regulation of corticotropin secretion(GO:0051461)
0.0	0.2	GO:0034755	iron ion transmembrane transport(GO:0034755)
0.0	0.3	GO:0042104	positive regulation of activated T cell proliferation(GO:0042104)
0.0	0.1	GO:0006167	AMP biosynthetic process(GO:0006167)
0.0	0.2	GO:0031061	negative regulation of histone methylation(GO:0031061)
0.0	0.2	GO:0022614	membrane to membrane docking(GO:0022614)
0.0	0.2	GO:0030889	negative regulation of B cell proliferation(GO:0030889)
0.0	0.5	GO:0031648	protein destabilization(GO:0031648)
0.0	0.1	GO:0006772	thiamine metabolic process(GO:0006772)
0.0	0.3	GO:0007064	mitotic sister chromatid cohesion(GO:0007064)
0.0	0.0	GO:0051152	positive regulation of smooth muscle cell differentiation(GO:0051152)
0.0	0.1	GO:0007221	positive regulation of transcription of Notch receptor target(GO:0007221)
0.0	0.1	GO:0010216	maintenance of DNA methylation(GO:0010216)
0.0	0.2	GO:0006104	succinyl-CoA metabolic process(GO:0006104)
0.0	0.1	GO:0048478	replication fork protection(GO:0048478)
0.0	0.1	GO:0035066	positive regulation of histone acetylation(GO:0035066) positive regulation of protein acetylation(GO:1901985) positive regulation of peptidyl-lysine acetylation(GO:2000758)
0.0	0.2	GO:0043984	histone H4-K16 acetylation(GO:0043984)
0.0	0.1	GO:0051533	positive regulation of NFAT protein import into nucleus(GO:0051533)
0.0	0.1	GO:0033194	response to hydroperoxide(GO:0033194)
0.0	0.1	GO:0033632	regulation of cell-cell adhesion mediated by integrin(GO:0033632)
0.0	0.1	GO:0001779	natural killer cell differentiation(GO:0001779)
0.0	0.2	GO:0036465	synaptic vesicle recycling(GO:0036465) synaptic vesicle endocytosis(GO:0048488) clathrin-mediated endocytosis(GO:0072583)
0.0	0.1	GO:0000019	regulation of mitotic recombination(GO:0000019)
0.0	0.1	GO:0009048	dosage compensation by inactivation of X chromosome(GO:0009048)
0.0	0.2	GO:0003056	regulation of vascular smooth muscle contraction(GO:0003056)
0.0	0.1	GO:0030948	negative regulation of vascular endothelial growth factor receptor signaling pathway(GO:0030948)
0.0	0.1	GO:0050765	negative regulation of phagocytosis(GO:0050765)
0.0	0.1	GO:0045603	positive regulation of endothelial cell differentiation(GO:0045603)
0.0	2.2	GO:0050852	T cell receptor signaling pathway(GO:0050852)
0.0	1.1	GO:0042059	negative regulation of epidermal growth factor receptor signaling pathway(GO:0042059) negative regulation of ERBB signaling pathway(GO:1901185)
0.0	0.5	GO:0046854	phosphatidylinositol phosphorylation(GO:0046854)
0.0	0.1	GO:0033345	asparagine catabolic process(GO:0006530) asparagine catabolic process via L-aspartate(GO:0033345)
0.0	0.1	GO:0001661	conditioned taste aversion(GO:0001661)
0.0	0.0	GO:0060298	positive regulation of sarcomere organization(GO:0060298)
0.0	0.1	GO:0051451	myoblast migration(GO:0051451)
0.0	0.2	GO:0036473	intrinsic apoptotic signaling pathway in response to oxidative stress(GO:0008631) cell death in response to oxidative stress(GO:0036473)
0.0	0.3	GO:0008608	attachment of spindle microtubules to kinetochore(GO:0008608)
0.0	0.2	GO:0032486	Rap protein signal transduction(GO:0032486)
0.0	0.1	GO:0006003	fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.0	0.1	GO:0034626	fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.0	0.2	GO:0007023	post-chaperonin tubulin folding pathway(GO:0007023)
0.0	0.1	GO:0032070	regulation of deoxyribonuclease activity(GO:0032070)
0.0	0.1	GO:0090116	DNA methylation on cytosine(GO:0032776) C-5 methylation of cytosine(GO:0090116)
0.0	0.2	GO:0050853	B cell receptor signaling pathway(GO:0050853)
0.0	0.1	GO:0045071	negative regulation of viral genome replication(GO:0045071)
0.0	0.1	GO:0017183	peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183)
0.0	0.1	GO:0043374	CD8-positive, alpha-beta T cell activation(GO:0036037) CD8-positive, alpha-beta T cell differentiation(GO:0043374)
0.0	0.1	GO:0002538	arachidonic acid metabolite production involved in inflammatory response(GO:0002538) leukotriene production involved in inflammatory response(GO:0002540)
0.0	0.4	GO:0070536	protein K63-linked deubiquitination(GO:0070536)
0.0	0.0	GO:0010613	positive regulation of cardiac muscle hypertrophy(GO:0010613) positive regulation of muscle hypertrophy(GO:0014742)
0.0	0.1	GO:0031167	rRNA methylation(GO:0031167)
0.0	0.1	GO:0060586	multicellular organismal iron ion homeostasis(GO:0060586)
0.0	0.2	GO:0035246	peptidyl-arginine N-methylation(GO:0035246)
0.0	0.1	GO:0002532	production of molecular mediator involved in inflammatory response(GO:0002532)
0.0	0.1	GO:0042159	lipoprotein catabolic process(GO:0042159)
0.0	0.5	GO:0032012	regulation of ARF protein signal transduction(GO:0032012)
0.0	0.2	GO:0003310	pancreatic A cell differentiation(GO:0003310)
0.0	0.4	GO:0045730	respiratory burst(GO:0045730)
0.0	0.2	GO:0050847	progesterone receptor signaling pathway(GO:0050847)
0.0	0.1	GO:0015801	aromatic amino acid transport(GO:0015801)
0.0	0.1	GO:0050685	positive regulation of mRNA 3'-end processing(GO:0031442) positive regulation of mRNA processing(GO:0050685) positive regulation of mRNA metabolic process(GO:1903313)
0.0	0.1	GO:0032914	positive regulation of transforming growth factor beta1 production(GO:0032914)
0.0	0.2	GO:0006658	phosphatidylserine metabolic process(GO:0006658)
0.0	0.1	GO:0009189	deoxyribonucleoside diphosphate biosynthetic process(GO:0009189)
0.0	0.1	GO:0032715	negative regulation of interleukin-6 production(GO:0032715)
0.0	0.1	GO:1901419	regulation of response to alcohol(GO:1901419)
0.0	0.1	GO:2001012	mesenchymal cell differentiation involved in kidney development(GO:0072161) metanephric mesenchymal cell differentiation(GO:0072162) mesenchymal cell differentiation involved in renal system development(GO:2001012)
0.0	0.3	GO:0045948	positive regulation of translational initiation(GO:0045948)
0.0	0.1	GO:0060023	soft palate development(GO:0060023)
0.0	0.2	GO:0090205	positive regulation of cholesterol metabolic process(GO:0090205)
0.0	0.2	GO:0010288	response to lead ion(GO:0010288)
0.0	0.1	GO:0006528	asparagine metabolic process(GO:0006528)
0.0	0.3	GO:0042403	thyroid hormone metabolic process(GO:0042403)
0.0	0.2	GO:0005513	detection of calcium ion(GO:0005513)
0.0	0.1	GO:0007035	vacuolar acidification(GO:0007035)
0.0	0.1	GO:0045793	positive regulation of cell size(GO:0045793)
0.0	0.0	GO:0050798	activated T cell proliferation(GO:0050798)
0.0	0.1	GO:0030910	olfactory placode formation(GO:0030910) olfactory placode development(GO:0071698) olfactory placode morphogenesis(GO:0071699)
0.0	0.1	GO:0034219	carbohydrate transmembrane transport(GO:0034219)
0.0	0.5	GO:0043124	negative regulation of I-kappaB kinase/NF-kappaB signaling(GO:0043124)
0.0	0.3	GO:0048199	vesicle targeting, to, from or within Golgi(GO:0048199)
0.0	0.1	GO:0071392	cellular response to estradiol stimulus(GO:0071392)
0.0	0.2	GO:0019883	antigen processing and presentation of endogenous antigen(GO:0019883)
0.0	0.1	GO:0061030	epithelial cell differentiation involved in mammary gland alveolus development(GO:0061030)
0.0	0.2	GO:1901072	amino sugar catabolic process(GO:0046348) glucosamine-containing compound catabolic process(GO:1901072)
0.0	0.0	GO:0050686	negative regulation of mRNA processing(GO:0050686) negative regulation of mRNA metabolic process(GO:1903312)
0.0	0.1	GO:0060710	chorio-allantoic fusion(GO:0060710)
0.0	0.1	GO:0042535	positive regulation of tumor necrosis factor biosynthetic process(GO:0042535)
0.0	0.1	GO:0071157	negative regulation of cell cycle arrest(GO:0071157)
0.0	0.1	GO:0006111	regulation of gluconeogenesis(GO:0006111)
0.0	0.1	GO:0061054	dermatome development(GO:0061054)
0.0	0.1	GO:0010759	positive regulation of macrophage chemotaxis(GO:0010759)
0.0	0.1	GO:0046831	regulation of RNA export from nucleus(GO:0046831)
0.0	0.1	GO:0006883	cellular sodium ion homeostasis(GO:0006883)
0.0	0.1	GO:0006681	galactosylceramide metabolic process(GO:0006681)
0.0	0.0	GO:0002862	negative regulation of inflammatory response to antigenic stimulus(GO:0002862)
0.0	0.0	GO:0046834	lipid phosphorylation(GO:0046834)
0.0	0.1	GO:0006474	N-terminal protein amino acid acetylation(GO:0006474)
0.0	0.0	GO:2000192	negative regulation of plasma membrane long-chain fatty acid transport(GO:0010748) negative regulation of anion transmembrane transport(GO:1903960) negative regulation of fatty acid transport(GO:2000192)
0.0	0.1	GO:0070296	sarcoplasmic reticulum calcium ion transport(GO:0070296)
0.0	0.1	GO:0031646	positive regulation of neurological system process(GO:0031646)
0.0	0.1	GO:0009405	pathogenesis(GO:0009405)
0.0	0.0	GO:0002478	antigen processing and presentation of exogenous peptide antigen(GO:0002478)
0.0	0.0	GO:0032494	response to peptidoglycan(GO:0032494)
0.0	0.1	GO:0045292	mRNA cis splicing, via spliceosome(GO:0045292)
0.0	0.1	GO:0002921	negative regulation of humoral immune response(GO:0002921)
0.0	0.3	GO:0042776	mitochondrial ATP synthesis coupled proton transport(GO:0042776)
0.0	0.1	GO:0019532	oxalate transport(GO:0019532)
0.0	0.0	GO:0031060	regulation of histone methylation(GO:0031060) regulation of histone H3-K4 methylation(GO:0051569)
0.0	0.1	GO:0070935	3'-UTR-mediated mRNA stabilization(GO:0070935)
0.0	0.4	GO:0016254	preassembly of GPI anchor in ER membrane(GO:0016254)
0.0	0.3	GO:0016578	histone deubiquitination(GO:0016578)
0.0	0.1	GO:0032814	regulation of natural killer cell activation(GO:0032814)
0.0	0.4	GO:0050832	defense response to fungus(GO:0050832)
0.0	0.1	GO:0045423	regulation of granulocyte macrophage colony-stimulating factor biosynthetic process(GO:0045423)
0.0	0.3	GO:0032008	positive regulation of TOR signaling(GO:0032008)
0.0	0.1	GO:0007008	outer mitochondrial membrane organization(GO:0007008) protein import into mitochondrial outer membrane(GO:0045040)
0.0	0.0	GO:0060751	epithelial cell proliferation involved in mammary gland duct elongation(GO:0060750) branch elongation involved in mammary gland duct branching(GO:0060751)
0.0	0.2	GO:0002286	T cell activation involved in immune response(GO:0002286)
0.0	0.1	GO:0045078	positive regulation of interferon-gamma biosynthetic process(GO:0045078)
0.0	0.3	GO:0098927	early endosome to late endosome transport(GO:0045022) vesicle-mediated transport between endosomal compartments(GO:0098927)
0.0	0.1	GO:0060528	secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development(GO:0060528)
0.0	0.5	GO:0006611	protein export from nucleus(GO:0006611)
0.0	0.1	GO:0032703	negative regulation of interleukin-2 production(GO:0032703)
0.0	0.0	GO:0002438	acute inflammatory response to antigenic stimulus(GO:0002438)
0.0	0.1	GO:0048535	lymph node development(GO:0048535)
0.0	0.2	GO:0015671	oxygen transport(GO:0015671)
0.0	0.0	GO:0070602	centromeric sister chromatid cohesion(GO:0070601) regulation of centromeric sister chromatid cohesion(GO:0070602)
0.0	0.1	GO:0010988	regulation of low-density lipoprotein particle clearance(GO:0010988)
0.0	0.0	GO:0035588	adenosine receptor signaling pathway(GO:0001973) G-protein coupled purinergic receptor signaling pathway(GO:0035588)
0.0	0.1	GO:0042117	monocyte activation(GO:0042117)
0.0	0.0	GO:1902745	positive regulation of lamellipodium assembly(GO:0010592) positive regulation of lamellipodium organization(GO:1902745)
0.0	0.2	GO:0051918	negative regulation of fibrinolysis(GO:0051918)
0.0	0.0	GO:0060620	regulation of cholesterol import(GO:0060620) regulation of sterol import(GO:2000909)
0.0	0.2	GO:0006337	nucleosome disassembly(GO:0006337) chromatin disassembly(GO:0031498) protein-DNA complex disassembly(GO:0032986)
0.0	0.1	GO:0009051	pentose-phosphate shunt, oxidative branch(GO:0009051)
0.0	0.2	GO:0043508	negative regulation of JUN kinase activity(GO:0043508)
0.0	0.1	GO:0070493	thrombin receptor signaling pathway(GO:0070493)
0.0	0.2	GO:0006465	signal peptide processing(GO:0006465)
0.0	0.1	GO:0019987	obsolete negative regulation of anti-apoptosis(GO:0019987)
0.0	0.0	GO:0043268	positive regulation of potassium ion transport(GO:0043268)
0.0	0.1	GO:0002717	positive regulation of natural killer cell mediated immunity(GO:0002717) positive regulation of natural killer cell mediated cytotoxicity(GO:0045954)
0.0	0.0	GO:0010831	positive regulation of myotube differentiation(GO:0010831)
0.0	0.1	GO:0006552	leucine catabolic process(GO:0006552)
0.0	0.0	GO:0002888	positive regulation of myeloid leukocyte mediated immunity(GO:0002888)
0.0	0.2	GO:0034372	triglyceride-rich lipoprotein particle remodeling(GO:0034370) very-low-density lipoprotein particle remodeling(GO:0034372)
0.0	0.1	GO:0010587	miRNA metabolic process(GO:0010586) miRNA catabolic process(GO:0010587)
0.0	0.1	GO:0051131	chaperone-mediated protein complex assembly(GO:0051131)
0.0	0.1	GO:0006999	nuclear pore organization(GO:0006999)
0.0	0.1	GO:0010508	positive regulation of autophagy(GO:0010508)
0.0	0.4	GO:0031295	lymphocyte costimulation(GO:0031294) T cell costimulation(GO:0031295)
0.0	0.1	GO:0060158	phospholipase C-activating dopamine receptor signaling pathway(GO:0060158)
0.0	0.0	GO:0052251	induction by organism of defense response of other organism involved in symbiotic interaction(GO:0052251)
0.0	0.1	GO:0040037	negative regulation of fibroblast growth factor receptor signaling pathway(GO:0040037)
0.0	0.0	GO:0097576	vacuole fusion(GO:0097576)
0.0	0.1	GO:0060017	parathyroid gland development(GO:0060017)
0.0	0.0	GO:0006154	adenosine catabolic process(GO:0006154)
0.0	0.0	GO:0034143	regulation of toll-like receptor 4 signaling pathway(GO:0034143)
0.0	0.0	GO:0015015	heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.0	0.1	GO:0003100	regulation of systemic arterial blood pressure by endothelin(GO:0003100)
0.0	0.0	GO:0043162	ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043162)
0.0	0.5	GO:0007257	activation of JUN kinase activity(GO:0007257)
0.0	0.1	GO:0060765	regulation of androgen receptor signaling pathway(GO:0060765)
0.0	0.1	GO:0033169	histone H3-K9 demethylation(GO:0033169)
0.0	0.0	GO:0045084	positive regulation of interleukin-12 biosynthetic process(GO:0045084)
0.0	0.0	GO:0070498	interleukin-1-mediated signaling pathway(GO:0070498)
0.0	0.1	GO:0035025	positive regulation of Rho protein signal transduction(GO:0035025)
0.0	0.3	GO:0035637	transmission of nerve impulse(GO:0019226) multicellular organismal signaling(GO:0035637)
0.0	0.1	GO:0060218	hematopoietic stem cell differentiation(GO:0060218)
0.0	0.0	GO:0021853	interneuron migration from the subpallium to the cortex(GO:0021830) cerebral cortex GABAergic interneuron migration(GO:0021853) cerebral cortex GABAergic interneuron development(GO:0021894) interneuron migration(GO:1904936)
0.0	0.0	GO:0014067	negative regulation of phosphatidylinositol 3-kinase signaling(GO:0014067)
0.0	0.0	GO:1903306	negative regulation of regulated secretory pathway(GO:1903306)
0.0	0.1	GO:0001573	ganglioside metabolic process(GO:0001573)
0.0	0.1	GO:0009812	flavonoid metabolic process(GO:0009812)
0.0	0.1	GO:0042532	negative regulation of tyrosine phosphorylation of Stat3 protein(GO:0042518) negative regulation of tyrosine phosphorylation of STAT protein(GO:0042532)
0.0	0.0	GO:0055015	ventricular cardiac muscle cell development(GO:0055015)
0.0	0.1	GO:0051657	maintenance of organelle location(GO:0051657)
0.0	0.1	GO:0009113	purine nucleobase biosynthetic process(GO:0009113)
0.0	0.1	GO:0060972	left/right pattern formation(GO:0060972)
0.0	0.1	GO:0043030	regulation of macrophage activation(GO:0043030)
0.0	0.3	GO:0034199	activation of protein kinase A activity(GO:0034199)
0.0	0.2	GO:0060334	regulation of response to interferon-gamma(GO:0060330) regulation of interferon-gamma-mediated signaling pathway(GO:0060334)
0.0	0.0	GO:0009313	oligosaccharide catabolic process(GO:0009313)
0.0	0.2	GO:0051205	protein insertion into membrane(GO:0051205)
0.0	0.2	GO:0043252	sodium-independent organic anion transport(GO:0043252)
0.0	0.1	GO:0006011	UDP-glucose metabolic process(GO:0006011)
0.0	0.2	GO:0043968	histone H2A acetylation(GO:0043968)
0.0	0.1	GO:1903038	negative regulation of T cell activation(GO:0050868) negative regulation of leukocyte cell-cell adhesion(GO:1903038)
0.0	0.0	GO:0030581	intracellular transport of viral protein in host cell(GO:0019060) symbiont intracellular protein transport in host(GO:0030581) regulation by virus of viral protein levels in host cell(GO:0046719) intracellular protein transport in other organism involved in symbiotic interaction(GO:0051708)
0.0	0.0	GO:0006925	inflammatory cell apoptotic process(GO:0006925)
0.0	0.1	GO:0006013	mannose metabolic process(GO:0006013)
0.0	0.1	GO:0006610	ribosomal protein import into nucleus(GO:0006610)
0.0	0.0	GO:0072239	metanephric glomerulus development(GO:0072224) metanephric glomerulus vasculature development(GO:0072239)
0.0	0.0	GO:0040016	embryonic cleavage(GO:0040016)
0.0	0.1	GO:0051290	protein heterotetramerization(GO:0051290)
0.0	0.7	GO:0006968	cellular defense response(GO:0006968)
0.0	0.6	GO:0060333	interferon-gamma-mediated signaling pathway(GO:0060333)
0.0	0.1	GO:0008611	ether lipid biosynthetic process(GO:0008611) glycerol ether biosynthetic process(GO:0046504) ether biosynthetic process(GO:1901503)
0.0	0.1	GO:0090224	regulation of spindle organization(GO:0090224)
0.0	0.1	GO:0000185	activation of MAPKKK activity(GO:0000185)
0.0	0.1	GO:0021854	hypothalamus development(GO:0021854)
0.0	0.0	GO:0007343	egg activation(GO:0007343)
0.0	0.1	GO:0015959	diadenosine polyphosphate metabolic process(GO:0015959)
0.0	0.2	GO:0090278	negative regulation of peptide secretion(GO:0002792) negative regulation of insulin secretion(GO:0046676) negative regulation of peptide hormone secretion(GO:0090278)
0.0	0.1	GO:0000733	DNA strand renaturation(GO:0000733)
0.0	0.0	GO:0010535	regulation of activation of JAK2 kinase activity(GO:0010534) positive regulation of activation of JAK2 kinase activity(GO:0010535)
0.0	0.2	GO:0007597	blood coagulation, intrinsic pathway(GO:0007597)
0.0	0.1	GO:0006105	succinate metabolic process(GO:0006105)
0.0	0.0	GO:0045824	negative regulation of innate immune response(GO:0045824)
0.0	0.0	GO:0051775	response to redox state(GO:0051775)
0.0	0.1	GO:0032790	ribosome disassembly(GO:0032790)
0.0	0.1	GO:0015816	glycine transport(GO:0015816)
0.0	0.1	GO:0006189	'de novo' IMP biosynthetic process(GO:0006189)
0.0	0.1	GO:0019695	choline metabolic process(GO:0019695)
0.0	0.0	GO:0048304	positive regulation of isotype switching to IgG isotypes(GO:0048304)
0.0	0.1	GO:0070389	chaperone cofactor-dependent protein refolding(GO:0070389)
0.0	0.2	GO:0034341	response to interferon-gamma(GO:0034341)
0.0	0.2	GO:0033138	positive regulation of peptidyl-serine phosphorylation(GO:0033138)
0.0	0.0	GO:0046548	retinal rod cell development(GO:0046548)
0.0	0.0	GO:0043267	negative regulation of potassium ion transport(GO:0043267)
0.0	0.0	GO:0071243	cellular response to arsenic-containing substance(GO:0071243)
0.0	0.1	GO:0009698	phenylpropanoid metabolic process(GO:0009698) coumarin metabolic process(GO:0009804)
0.0	0.1	GO:1903078	positive regulation of establishment of protein localization to plasma membrane(GO:0090004) positive regulation of protein localization to plasma membrane(GO:1903078) positive regulation of protein localization to cell periphery(GO:1904377)
0.0	0.0	GO:0043570	maintenance of DNA repeat elements(GO:0043570)
0.0	0.1	GO:0006420	arginyl-tRNA aminoacylation(GO:0006420)
0.0	0.2	GO:0043101	purine-containing compound salvage(GO:0043101)
0.0	0.0	GO:0060219	camera-type eye photoreceptor cell differentiation(GO:0060219)
0.0	0.0	GO:0010980	regulation of vitamin D 24-hydroxylase activity(GO:0010979) positive regulation of vitamin D 24-hydroxylase activity(GO:0010980)
0.0	0.0	GO:2000114	regulation of establishment of cell polarity(GO:2000114)
0.0	0.2	GO:0006379	mRNA cleavage(GO:0006379)
0.0	0.1	GO:0045737	positive regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045737) positive regulation of cyclin-dependent protein kinase activity(GO:1904031)
0.0	0.0	GO:0006828	manganese ion transport(GO:0006828)
0.0	0.1	GO:0009235	cobalamin metabolic process(GO:0009235)
0.0	0.0	GO:0031223	auditory behavior(GO:0031223)
0.0	0.0	GO:0042362	fat-soluble vitamin biosynthetic process(GO:0042362)
0.0	0.1	GO:0060056	mammary gland involution(GO:0060056)
0.0	0.0	GO:0090201	negative regulation of mitochondrion organization(GO:0010823) negative regulation of release of cytochrome c from mitochondria(GO:0090201) negative regulation of apoptotic signaling pathway(GO:2001234)
0.0	0.0	GO:0000089	mitotic metaphase(GO:0000089)
0.0	0.1	GO:0016557	peroxisome membrane biogenesis(GO:0016557)
0.0	1.2	GO:0018279	peptidyl-asparagine modification(GO:0018196) protein N-linked glycosylation via asparagine(GO:0018279)
0.0	0.2	GO:0007158	neuron cell-cell adhesion(GO:0007158)
0.0	1.1	GO:0000216	obsolete M/G1 transition of mitotic cell cycle(GO:0000216)
0.0	0.1	GO:0045672	positive regulation of osteoclast differentiation(GO:0045672)
0.0	0.0	GO:0017085	response to insecticide(GO:0017085)
0.0	0.2	GO:0018208	peptidyl-proline modification(GO:0018208)
0.0	0.0	GO:0060573	ventral spinal cord interneuron specification(GO:0021521) cell fate specification involved in pattern specification(GO:0060573)
0.0	0.0	GO:0009214	cyclic nucleotide catabolic process(GO:0009214)
0.0	0.3	GO:2000060	regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process(GO:2000058) positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process(GO:2000060)
0.0	0.1	GO:0019441	tryptophan catabolic process to kynurenine(GO:0019441)
0.0	0.1	GO:0042219	cellular modified amino acid catabolic process(GO:0042219)
0.0	0.0	GO:0019509	L-methionine biosynthetic process from methylthioadenosine(GO:0019509)
0.0	0.0	GO:0046668	regulation of retinal cell programmed cell death(GO:0046668)
0.0	0.1	GO:0015693	magnesium ion transport(GO:0015693)
0.0	0.1	GO:0006623	protein targeting to lysosome(GO:0006622) protein targeting to vacuole(GO:0006623) protein localization to lysosome(GO:0061462) protein localization to vacuole(GO:0072665) establishment of protein localization to vacuole(GO:0072666)
0.0	0.1	GO:0021683	cerebellar granular layer development(GO:0021681) cerebellar granular layer morphogenesis(GO:0021683) cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707)
0.0	0.7	GO:0071427	mRNA export from nucleus(GO:0006406) mRNA-containing ribonucleoprotein complex export from nucleus(GO:0071427)
0.0	0.1	GO:0000083	regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083)
0.0	0.1	GO:0034314	Arp2/3 complex-mediated actin nucleation(GO:0034314)
0.0	0.1	GO:0006498	N-terminal protein lipidation(GO:0006498)
0.0	0.0	GO:0008291	acetylcholine metabolic process(GO:0008291) acetate ester metabolic process(GO:1900619)
0.0	0.1	GO:0001510	RNA methylation(GO:0001510)
0.0	0.1	GO:0009209	GTP biosynthetic process(GO:0006183) UTP biosynthetic process(GO:0006228) CTP biosynthetic process(GO:0006241) pyrimidine ribonucleoside triphosphate metabolic process(GO:0009208) pyrimidine ribonucleoside triphosphate biosynthetic process(GO:0009209) CTP metabolic process(GO:0046036) UTP metabolic process(GO:0046051)
0.0	0.1	GO:0033483	gas homeostasis(GO:0033483)
0.0	0.0	GO:0070232	regulation of T cell apoptotic process(GO:0070232)
0.0	0.1	GO:0046513	ceramide biosynthetic process(GO:0046513)
0.0	0.1	GO:0006546	glycine catabolic process(GO:0006546)
0.0	0.0	GO:0031573	intra-S DNA damage checkpoint(GO:0031573)
0.0	0.0	GO:0090009	primitive streak formation(GO:0090009)
0.0	0.0	GO:0045162	clustering of voltage-gated sodium channels(GO:0045162)
0.0	0.1	GO:0051103	DNA ligation involved in DNA repair(GO:0051103)
0.0	0.1	GO:0000183	chromatin silencing at rDNA(GO:0000183)
0.0	0.0	GO:0051095	regulation of helicase activity(GO:0051095) positive regulation of helicase activity(GO:0051096)
0.0	0.0	GO:0035434	copper ion transmembrane transport(GO:0035434)
0.0	0.0	GO:0019731	antibacterial humoral response(GO:0019731)
0.0	0.1	GO:0050732	negative regulation of peptidyl-tyrosine phosphorylation(GO:0050732)
0.0	0.0	GO:0010832	negative regulation of myotube differentiation(GO:0010832)
0.0	0.0	GO:0034720	histone H3-K4 demethylation(GO:0034720)
0.0	0.0	GO:0034421	post-translational protein acetylation(GO:0034421)
0.0	0.0	GO:0006998	nuclear envelope organization(GO:0006998)
0.0	0.1	GO:0042771	intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator(GO:0042771)
0.0	0.1	GO:0046149	porphyrin-containing compound catabolic process(GO:0006787) tetrapyrrole catabolic process(GO:0033015) heme catabolic process(GO:0042167) pigment catabolic process(GO:0046149)
0.0	0.0	GO:0060197	cloaca development(GO:0035844) cloacal septation(GO:0060197)
0.0	0.0	GO:0006047	UDP-N-acetylglucosamine metabolic process(GO:0006047)
0.0	0.2	GO:1903039	positive regulation of T cell activation(GO:0050870) positive regulation of leukocyte cell-cell adhesion(GO:1903039)
0.0	0.0	GO:2000191	regulation of fatty acid transport(GO:2000191)
0.0	0.1	GO:0016180	snRNA processing(GO:0016180)
0.0	0.5	GO:0019722	calcium-mediated signaling(GO:0019722)
0.0	0.0	GO:0002068	glandular epithelial cell development(GO:0002068)
0.0	0.0	GO:0021797	forebrain anterior/posterior pattern specification(GO:0021797)
0.0	0.0	GO:0030309	poly-N-acetyllactosamine metabolic process(GO:0030309)
0.0	0.1	GO:0042987	amyloid precursor protein catabolic process(GO:0042987)
0.0	0.0	GO:1903020	positive regulation of glycoprotein biosynthetic process(GO:0010560) positive regulation of glycoprotein metabolic process(GO:1903020)
0.0	0.1	GO:0007076	mitotic chromosome condensation(GO:0007076)
0.0	0.3	GO:0000289	nuclear-transcribed mRNA poly(A) tail shortening(GO:0000289)
0.0	0.0	GO:0042435	indole-containing compound biosynthetic process(GO:0042435)
0.0	0.1	GO:0060760	positive regulation of response to cytokine stimulus(GO:0060760)
0.0	0.4	GO:0070646	protein modification by small protein removal(GO:0070646)
0.0	0.1	GO:0006301	postreplication repair(GO:0006301)
0.0	0.1	GO:0007340	acrosome reaction(GO:0007340)
0.0	0.0	GO:0033505	floor plate formation(GO:0021508) floor plate morphogenesis(GO:0033505)
0.0	0.0	GO:0061028	establishment of endothelial barrier(GO:0061028)
0.0	0.1	GO:0009312	oligosaccharide biosynthetic process(GO:0009312)
0.0	0.0	GO:0051594	detection of carbohydrate stimulus(GO:0009730) detection of hexose stimulus(GO:0009732) detection of monosaccharide stimulus(GO:0034287) detection of glucose(GO:0051594)
0.0	0.1	GO:0051453	regulation of intracellular pH(GO:0051453)
0.0	0.1	GO:0032210	regulation of telomere maintenance via telomerase(GO:0032210)
0.0	0.1	GO:0018065	protein-cofactor linkage(GO:0018065)
0.0	0.0	GO:0007100	mitotic centrosome separation(GO:0007100)
0.0	0.0	GO:0007144	female meiosis I(GO:0007144)
0.0	0.0	GO:0043618	regulation of transcription from RNA polymerase II promoter in response to stress(GO:0043618) regulation of transcription from RNA polymerase II promoter in response to oxidative stress(GO:0043619)
0.0	0.0	GO:0045910	negative regulation of DNA recombination(GO:0045910)
0.0	0.0	GO:0033158	regulation of protein import into nucleus, translocation(GO:0033158)
0.0	0.1	GO:0019433	triglyceride catabolic process(GO:0019433) neutral lipid catabolic process(GO:0046461) acylglycerol catabolic process(GO:0046464)
0.0	0.1	GO:0051568	histone H3-K4 methylation(GO:0051568)
0.0	0.0	GO:0034112	positive regulation of homotypic cell-cell adhesion(GO:0034112)
0.0	0.1	GO:0051602	response to electrical stimulus(GO:0051602)
0.0	0.0	GO:0060359	response to ammonium ion(GO:0060359)
0.0	0.0	GO:0042447	hormone catabolic process(GO:0042447)
0.0	0.0	GO:0001547	antral ovarian follicle growth(GO:0001547)
0.0	0.2	GO:0034612	response to tumor necrosis factor(GO:0034612)
0.0	0.0	GO:0042415	norepinephrine metabolic process(GO:0042415)
0.0	0.1	GO:0006685	sphingomyelin catabolic process(GO:0006685)
0.0	0.1	GO:0016556	mRNA modification(GO:0016556)
0.0	0.0	GO:0051927	obsolete negative regulation of calcium ion transport via voltage-gated calcium channel activity(GO:0051927)
0.0	0.1	GO:0045008	depyrimidination(GO:0045008)
0.0	0.0	GO:1904748	regulation of apoptotic process involved in morphogenesis(GO:1902337) regulation of apoptotic process involved in development(GO:1904748)
0.0	0.0	GO:0002238	response to molecule of fungal origin(GO:0002238)
0.0	0.1	GO:0035095	behavioral response to nicotine(GO:0035095)
0.0	0.0	GO:0045945	positive regulation of transcription from RNA polymerase III promoter(GO:0045945)
0.0	0.3	GO:0050772	positive regulation of axonogenesis(GO:0050772)
0.0	0.1	GO:0035121	obsolete tail morphogenesis(GO:0035121)
0.0	0.1	GO:0006903	vesicle targeting(GO:0006903)
0.0	0.0	GO:0045780	positive regulation of tissue remodeling(GO:0034105) positive regulation of bone resorption(GO:0045780) positive regulation of bone remodeling(GO:0046852)
0.0	0.2	GO:0006513	protein monoubiquitination(GO:0006513)
0.0	0.0	GO:0010107	potassium ion import(GO:0010107)
0.0	0.0	GO:0048808	male genitalia morphogenesis(GO:0048808) male anatomical structure morphogenesis(GO:0090598)
0.0	0.0	GO:0044803	multi-organism membrane organization(GO:0044803)
0.0	0.1	GO:0048169	regulation of long-term neuronal synaptic plasticity(GO:0048169)
0.0	0.1	GO:0007141	male meiosis I(GO:0007141)
0.0	0.0	GO:0035092	sperm chromatin condensation(GO:0035092)
0.0	0.1	GO:1901663	quinone biosynthetic process(GO:1901663)
0.0	0.0	GO:0009223	pyrimidine deoxyribonucleotide catabolic process(GO:0009223)
0.0	0.1	GO:0042462	eye photoreceptor cell development(GO:0042462)
0.0	0.1	GO:0007339	binding of sperm to zona pellucida(GO:0007339) sperm-egg recognition(GO:0035036)
0.0	0.0	GO:0021936	regulation of cerebellar granule cell precursor proliferation(GO:0021936) positive regulation of cerebellar granule cell precursor proliferation(GO:0021940)
0.0	0.0	GO:0050650	chondroitin sulfate proteoglycan biosynthetic process(GO:0050650)
0.0	0.0	GO:0002230	positive regulation of defense response to virus by host(GO:0002230)
0.0	0.0	GO:0008628	hormone-mediated apoptotic signaling pathway(GO:0008628)
0.0	0.1	GO:0032456	endocytic recycling(GO:0032456)
0.0	0.1	GO:0032092	positive regulation of protein binding(GO:0032092)
0.0	0.0	GO:0071436	sodium ion export(GO:0071436)
0.0	0.2	GO:0007190	activation of adenylate cyclase activity(GO:0007190)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.4	GO:0042105	alpha-beta T cell receptor complex(GO:0042105)
0.1	0.3	GO:0070022	transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.1	0.2	GO:0000942	condensed nuclear chromosome outer kinetochore(GO:0000942)
0.1	0.5	GO:0001891	phagocytic cup(GO:0001891)
0.1	0.1	GO:0031932	TORC2 complex(GO:0031932)
0.1	0.2	GO:0072487	MSL complex(GO:0072487)
0.1	0.2	GO:0000306	extrinsic component of vacuolar membrane(GO:0000306) extrinsic component of endosome membrane(GO:0031313)
0.1	0.5	GO:0070688	MLL5-L complex(GO:0070688)
0.1	0.2	GO:0005826	actomyosin contractile ring(GO:0005826)
0.1	0.3	GO:0031088	platelet dense granule membrane(GO:0031088)
0.1	0.2	GO:0034992	microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.1	0.5	GO:0042101	T cell receptor complex(GO:0042101)
0.1	0.8	GO:0005942	phosphatidylinositol 3-kinase complex(GO:0005942)
0.1	0.5	GO:0008250	oligosaccharyltransferase complex(GO:0008250)
0.1	0.2	GO:0043218	compact myelin(GO:0043218)
0.0	0.1	GO:0000506	glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.0	0.5	GO:0001772	immunological synapse(GO:0001772)
0.0	0.1	GO:0032009	early phagosome(GO:0032009)
0.0	0.2	GO:0070695	FHF complex(GO:0070695)
0.0	0.1	GO:0000164	protein phosphatase type 1 complex(GO:0000164)
0.0	1.4	GO:0030175	filopodium(GO:0030175)
0.0	0.0	GO:0031235	intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.0	0.2	GO:0031264	death-inducing signaling complex(GO:0031264)
0.0	0.1	GO:0031254	uropod(GO:0001931) cell trailing edge(GO:0031254)
0.0	1.2	GO:0005626	obsolete insoluble fraction(GO:0005626)
0.0	0.1	GO:0033011	perinuclear theca(GO:0033011)
0.0	0.2	GO:0000153	cytoplasmic ubiquitin ligase complex(GO:0000153)
0.0	0.2	GO:0033256	I-kappaB/NF-kappaB complex(GO:0033256)
0.0	0.2	GO:0014731	spectrin-associated cytoskeleton(GO:0014731)
0.0	0.1	GO:0032777	Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.0	0.1	GO:0032133	chromosome passenger complex(GO:0032133)
0.0	0.2	GO:0000276	mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.0	1.5	GO:0030173	integral component of Golgi membrane(GO:0030173)
0.0	0.1	GO:0005594	collagen type IX trimer(GO:0005594)
0.0	0.4	GO:0034362	low-density lipoprotein particle(GO:0034362)
0.0	0.1	GO:0005827	polar microtubule(GO:0005827)
0.0	0.2	GO:0032839	dendrite cytoplasm(GO:0032839)
0.0	0.2	GO:0044224	juxtaparanode region of axon(GO:0044224)
0.0	0.2	GO:0000796	condensin complex(GO:0000796)
0.0	0.3	GO:0010494	cytoplasmic stress granule(GO:0010494)
0.0	0.1	GO:0070820	tertiary granule(GO:0070820)
0.0	0.1	GO:0030895	apolipoprotein B mRNA editing enzyme complex(GO:0030895)
0.0	0.1	GO:0016593	Cdc73/Paf1 complex(GO:0016593)
0.0	0.1	GO:0035189	Rb-E2F complex(GO:0035189)
0.0	0.1	GO:0000800	lateral element(GO:0000800)
0.0	0.3	GO:0033276	transcription factor TFTC complex(GO:0033276)
0.0	0.2	GO:0005845	mRNA cap binding complex(GO:0005845) RNA cap binding complex(GO:0034518)
0.0	0.1	GO:0000137	Golgi cis cisterna(GO:0000137)
0.0	0.2	GO:0000125	PCAF complex(GO:0000125)
0.0	0.2	GO:0042627	chylomicron(GO:0042627)
0.0	0.1	GO:0044462	external encapsulating structure part(GO:0044462)
0.0	0.3	GO:0016471	vacuolar proton-transporting V-type ATPase complex(GO:0016471)
0.0	0.5	GO:0000159	protein phosphatase type 2A complex(GO:0000159)
0.0	0.1	GO:0071438	invadopodium membrane(GO:0071438)
0.0	0.2	GO:0005664	origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.0	0.4	GO:0005892	acetylcholine-gated channel complex(GO:0005892)
0.0	0.2	GO:0008290	F-actin capping protein complex(GO:0008290)
0.0	0.2	GO:0071778	obsolete WINAC complex(GO:0071778)
0.0	0.1	GO:0005686	U2 snRNP(GO:0005686)
0.0	0.1	GO:0005721	pericentric heterochromatin(GO:0005721)
0.0	0.1	GO:0005662	DNA replication factor A complex(GO:0005662)
0.0	0.2	GO:0043020	NADPH oxidase complex(GO:0043020)
0.0	0.1	GO:0031465	Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
0.0	0.1	GO:1990316	ATG1/ULK1 kinase complex(GO:1990316)
0.0	0.1	GO:0030062	mitochondrial tricarboxylic acid cycle enzyme complex(GO:0030062)
0.0	0.5	GO:0019005	SCF ubiquitin ligase complex(GO:0019005)
0.0	0.2	GO:0019773	proteasome core complex, alpha-subunit complex(GO:0019773)
0.0	0.3	GO:0035631	CD40 receptor complex(GO:0035631)
0.0	0.2	GO:0042555	MCM complex(GO:0042555)
0.0	0.2	GO:0031080	nuclear pore outer ring(GO:0031080)
0.0	0.4	GO:0000932	cytoplasmic mRNA processing body(GO:0000932)
0.0	0.3	GO:0005720	nuclear heterochromatin(GO:0005720)
0.0	0.2	GO:0005697	telomerase holoenzyme complex(GO:0005697)
0.0	0.1	GO:0000300	obsolete peripheral to membrane of membrane fraction(GO:0000300)
0.0	0.1	GO:0061200	clathrin-sculpted gamma-aminobutyric acid transport vesicle(GO:0061200) clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane(GO:0061202)
0.0	0.1	GO:0005797	Golgi medial cisterna(GO:0005797)
0.0	0.1	GO:0031371	ubiquitin conjugating enzyme complex(GO:0031371)
0.0	0.1	GO:0000791	euchromatin(GO:0000791)
0.0	0.1	GO:0010369	chromocenter(GO:0010369)
0.0	2.5	GO:0009897	external side of plasma membrane(GO:0009897)
0.0	0.2	GO:0032039	integrator complex(GO:0032039)
0.0	0.1	GO:0032590	dendrite membrane(GO:0032590)
0.0	0.4	GO:0016328	lateral plasma membrane(GO:0016328)
0.0	0.1	GO:0043190	ATP-binding cassette (ABC) transporter complex(GO:0043190)
0.0	0.1	GO:0045179	apical cortex(GO:0045179)
0.0	0.1	GO:0048786	presynaptic active zone(GO:0048786)
0.0	0.1	GO:0008537	proteasome activator complex(GO:0008537)
0.0	0.1	GO:0032389	MutLalpha complex(GO:0032389)
0.0	0.2	GO:0031105	septin complex(GO:0031105) septin cytoskeleton(GO:0032156)
0.0	0.3	GO:0030530	obsolete heterogeneous nuclear ribonucleoprotein complex(GO:0030530)
0.0	0.1	GO:0008282	ATP-sensitive potassium channel complex(GO:0008282)
0.0	0.1	GO:0070188	obsolete Stn1-Ten1 complex(GO:0070188)
0.0	0.2	GO:0060293	P granule(GO:0043186) pole plasm(GO:0045495) germ plasm(GO:0060293)
0.0	0.1	GO:0005883	neurofilament(GO:0005883)
0.0	0.1	GO:0045120	pronucleus(GO:0045120)
0.0	0.1	GO:0033553	rDNA heterochromatin(GO:0033553)
0.0	0.1	GO:0031305	integral component of mitochondrial inner membrane(GO:0031305)
0.0	0.2	GO:0005852	eukaryotic translation initiation factor 3 complex(GO:0005852)
0.0	0.1	GO:0001741	XY body(GO:0001741)
0.0	0.1	GO:0005863	striated muscle myosin thick filament(GO:0005863)
0.0	0.1	GO:0042629	mast cell granule(GO:0042629)
0.0	0.1	GO:0005682	U5 snRNP(GO:0005682)
0.0	0.1	GO:0030904	retromer complex(GO:0030904)
0.0	0.8	GO:0016605	PML body(GO:0016605)
0.0	0.1	GO:0005641	nuclear envelope lumen(GO:0005641)
0.0	0.1	GO:0030877	beta-catenin destruction complex(GO:0030877)
0.0	0.1	GO:0070776	H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.0	0.0	GO:0031304	intrinsic component of mitochondrial inner membrane(GO:0031304)
0.0	0.1	GO:0031463	Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0	0.1	GO:0031464	Cul4A-RING E3 ubiquitin ligase complex(GO:0031464)
0.0	0.1	GO:0035098	ESC/E(Z) complex(GO:0035098)
0.0	0.2	GO:0016235	aggresome(GO:0016235)
0.0	0.1	GO:0005750	mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
0.0	0.1	GO:0030897	HOPS complex(GO:0030897)
0.0	0.1	GO:0070761	pre-snoRNP complex(GO:0070761)
0.0	0.1	GO:0000275	mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275)
0.0	0.0	GO:0001652	granular component(GO:0001652)
0.0	0.4	GO:0030667	secretory granule membrane(GO:0030667)
0.0	0.0	GO:0031205	endoplasmic reticulum Sec complex(GO:0031205)
0.0	0.1	GO:0019907	cyclin-dependent protein kinase activating kinase holoenzyme complex(GO:0019907)
0.0	0.1	GO:0008180	COP9 signalosome(GO:0008180)
0.0	0.1	GO:0005652	nuclear lamina(GO:0005652)
0.0	0.0	GO:0016533	cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533)
0.0	0.1	GO:0001740	Barr body(GO:0001740)
0.0	0.0	GO:0000792	heterochromatin(GO:0000792)
0.0	0.1	GO:0031010	ISWI-type complex(GO:0031010)
0.0	0.1	GO:0031616	spindle pole centrosome(GO:0031616)
0.0	0.0	GO:0008540	proteasome regulatory particle, base subcomplex(GO:0008540)
0.0	0.2	GO:0000315	organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.0	0.1	GO:0032279	asymmetric synapse(GO:0032279) neuron to neuron synapse(GO:0098984)
0.0	0.1	GO:0005753	mitochondrial proton-transporting ATP synthase complex(GO:0005753)
0.0	0.1	GO:0005839	proteasome core complex(GO:0005839)
0.0	0.6	GO:0031901	early endosome membrane(GO:0031901)
0.0	0.0	GO:0033179	proton-transporting V-type ATPase, V0 domain(GO:0033179)
0.0	0.3	GO:0031526	brush border membrane(GO:0031526)
0.0	0.1	GO:0000346	transcription export complex(GO:0000346)
0.0	0.0	GO:0000803	sex chromosome(GO:0000803)
0.0	0.1	GO:0035267	NuA4 histone acetyltransferase complex(GO:0035267)
0.0	0.1	GO:0005671	Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
0.0	0.4	GO:0009295	nucleoid(GO:0009295)
0.0	0.1	GO:0022624	proteasome accessory complex(GO:0022624)
0.0	0.1	GO:0031083	BLOC complex(GO:0031082) BLOC-1 complex(GO:0031083)
0.0	0.4	GO:0000502	proteasome complex(GO:0000502)
0.0	0.0	GO:0030688	preribosome, small subunit precursor(GO:0030688)
0.0	0.0	GO:0045323	interleukin-1 receptor complex(GO:0045323)
0.0	0.2	GO:0033116	endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
0.0	0.0	GO:0072357	PTW/PP1 phosphatase complex(GO:0072357)
0.0	0.0	GO:0034045	pre-autophagosomal structure membrane(GO:0034045)
0.0	0.0	GO:1902562	H4/H2A histone acetyltransferase complex(GO:0043189) H4 histone acetyltransferase complex(GO:1902562)
0.0	0.0	GO:0042824	MHC class I peptide loading complex(GO:0042824)
0.0	0.1	GO:0008278	cohesin complex(GO:0008278)
0.0	0.1	GO:0005669	transcription factor TFIID complex(GO:0005669)
0.0	0.1	GO:0005868	cytoplasmic dynein complex(GO:0005868)
0.0	0.0	GO:0000124	SAGA complex(GO:0000124)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	0.6	GO:0008454	alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.2	0.5	GO:0035184	histone threonine kinase activity(GO:0035184)
0.2	0.6	GO:0047238	glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity(GO:0047238)
0.1	0.4	GO:0033691	sialic acid binding(GO:0033691)
0.1	0.8	GO:0016494	C-X-C chemokine receptor activity(GO:0016494)
0.1	0.4	GO:0004465	lipoprotein lipase activity(GO:0004465)
0.1	0.4	GO:0046935	1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.1	1.1	GO:0016493	C-C chemokine receptor activity(GO:0016493)
0.1	1.3	GO:0004697	protein kinase C activity(GO:0004697)
0.1	0.3	GO:0003836	beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.1	0.5	GO:0052813	phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) phosphatidylinositol bisphosphate kinase activity(GO:0052813)
0.1	0.1	GO:0042608	T cell receptor binding(GO:0042608)
0.1	0.4	GO:0019911	structural constituent of myelin sheath(GO:0019911)
0.1	0.3	GO:0004911	interleukin-2 receptor activity(GO:0004911)
0.1	0.3	GO:0016309	1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
0.1	0.4	GO:0030284	estrogen receptor activity(GO:0030284)
0.1	0.6	GO:0070087	chromo shadow domain binding(GO:0070087)
0.1	0.3	GO:0047623	AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.1	0.4	GO:0031013	troponin I binding(GO:0031013)
0.1	0.2	GO:0016842	amidine-lyase activity(GO:0016842)
0.1	0.2	GO:0030375	thyroid hormone receptor coactivator activity(GO:0030375)
0.1	0.7	GO:0034593	phosphatidylinositol bisphosphate phosphatase activity(GO:0034593)
0.1	1.2	GO:0030159	receptor signaling complex scaffold activity(GO:0030159)
0.1	0.3	GO:0004062	aryl sulfotransferase activity(GO:0004062)
0.1	0.4	GO:0005314	high-affinity glutamate transmembrane transporter activity(GO:0005314)
0.1	0.2	GO:0008545	JUN kinase kinase activity(GO:0008545)
0.1	0.1	GO:0016314	phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity(GO:0016314)
0.1	1.6	GO:0045028	G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.1	0.2	GO:0047756	chondroitin 4-sulfotransferase activity(GO:0047756)
0.1	0.8	GO:0005095	GTPase inhibitor activity(GO:0005095)
0.1	0.2	GO:0043398	HLH domain binding(GO:0043398)
0.1	0.2	GO:0000247	C-8 sterol isomerase activity(GO:0000247)
0.1	1.0	GO:0004115	3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.1	0.2	GO:0070053	thrombospondin receptor activity(GO:0070053)
0.1	0.3	GO:0005131	growth hormone receptor binding(GO:0005131)
0.1	0.2	GO:0015925	galactosidase activity(GO:0015925)
0.1	1.2	GO:0005164	tumor necrosis factor receptor binding(GO:0005164)
0.1	0.6	GO:0015924	mannosyl-oligosaccharide mannosidase activity(GO:0015924)
0.1	0.5	GO:0004579	dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.1	0.3	GO:0005381	iron ion transmembrane transporter activity(GO:0005381)
0.1	0.1	GO:0032139	dinucleotide insertion or deletion binding(GO:0032139)
0.1	0.4	GO:0030332	cyclin binding(GO:0030332)
0.1	0.3	GO:0001784	phosphotyrosine binding(GO:0001784)
0.1	0.4	GO:0015271	outward rectifier potassium channel activity(GO:0015271)
0.1	0.2	GO:0004591	oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591)
0.1	0.2	GO:0004719	protein-L-isoaspartate (D-aspartate) O-methyltransferase activity(GO:0004719)
0.0	0.2	GO:0004774	succinate-CoA ligase activity(GO:0004774)
0.0	0.3	GO:0003828	alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.0	0.1	GO:0043325	phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.0	0.2	GO:0004950	G-protein coupled chemoattractant receptor activity(GO:0001637) chemokine receptor activity(GO:0004950)
0.0	0.1	GO:0003910	DNA ligase activity(GO:0003909) DNA ligase (ATP) activity(GO:0003910)
0.0	0.2	GO:0016004	phospholipase activator activity(GO:0016004)
0.0	0.1	GO:0004351	glutamate decarboxylase activity(GO:0004351)
0.0	0.4	GO:0019864	IgG binding(GO:0019864)
0.0	0.0	GO:0010314	phosphatidylinositol-5-phosphate binding(GO:0010314)
0.0	0.5	GO:0051018	protein kinase A binding(GO:0051018)
0.0	0.2	GO:0001609	G-protein coupled adenosine receptor activity(GO:0001609)
0.0	0.1	GO:0042156	obsolete zinc-mediated transcriptional activator activity(GO:0042156)
0.0	2.1	GO:0005070	SH3/SH2 adaptor activity(GO:0005070)
0.0	0.1	GO:0050544	arachidonic acid binding(GO:0050544)
0.0	0.0	GO:0035197	siRNA binding(GO:0035197)
0.0	0.2	GO:0008526	phosphatidylinositol transporter activity(GO:0008526)
0.0	0.1	GO:0008474	palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.0	0.1	GO:0050253	retinyl-palmitate esterase activity(GO:0050253)
0.0	0.5	GO:0031593	polyubiquitin binding(GO:0031593)
0.0	0.1	GO:0060230	lipoprotein lipase activator activity(GO:0060230)
0.0	0.2	GO:0008649	rRNA methyltransferase activity(GO:0008649)
0.0	0.0	GO:0010861	thyroid hormone receptor activator activity(GO:0010861)
0.0	0.1	GO:0031628	opioid receptor binding(GO:0031628)
0.0	0.6	GO:0005086	ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0	0.1	GO:0003953	NAD+ nucleosidase activity(GO:0003953)
0.0	0.9	GO:0003950	NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.0	0.2	GO:0015057	thrombin receptor activity(GO:0015057)
0.0	0.1	GO:0034481	chondroitin sulfotransferase activity(GO:0034481)
0.0	0.2	GO:0004046	aminoacylase activity(GO:0004046)
0.0	0.9	GO:0004435	phosphatidylinositol phospholipase C activity(GO:0004435)
0.0	0.2	GO:0070577	lysine-acetylated histone binding(GO:0070577)
0.0	0.2	GO:0031435	mitogen-activated protein kinase kinase kinase binding(GO:0031435)
0.0	0.2	GO:0004904	interferon receptor activity(GO:0004904)
0.0	0.2	GO:0030955	potassium ion binding(GO:0030955)
0.0	0.3	GO:0016274	arginine N-methyltransferase activity(GO:0016273) protein-arginine N-methyltransferase activity(GO:0016274)
0.0	0.2	GO:0034452	dynactin binding(GO:0034452)
0.0	0.1	GO:0017056	structural constituent of nuclear pore(GO:0017056)
0.0	0.1	GO:0004607	phosphatidylcholine-sterol O-acyltransferase activity(GO:0004607)
0.0	0.3	GO:0046625	sphingolipid binding(GO:0046625)
0.0	0.2	GO:0004568	chitinase activity(GO:0004568)
0.0	0.0	GO:0035014	phosphatidylinositol 3-kinase regulator activity(GO:0035014)
0.0	0.2	GO:0031701	angiotensin receptor binding(GO:0031701)
0.0	1.8	GO:0008301	DNA binding, bending(GO:0008301)
0.0	0.3	GO:0008553	hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.0	1.1	GO:0004715	non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.0	0.1	GO:0004974	leukotriene receptor activity(GO:0004974)
0.0	0.2	GO:0016520	growth hormone-releasing hormone receptor activity(GO:0016520)
0.0	0.4	GO:0008373	sialyltransferase activity(GO:0008373)
0.0	0.3	GO:0005338	nucleotide-sugar transmembrane transporter activity(GO:0005338)
0.0	0.1	GO:0005087	Ran guanyl-nucleotide exchange factor activity(GO:0005087)
0.0	0.1	GO:0004060	arylamine N-acetyltransferase activity(GO:0004060)
0.0	0.1	GO:0001758	retinal dehydrogenase activity(GO:0001758)
0.0	0.3	GO:0048531	beta-1,3-galactosyltransferase activity(GO:0048531)
0.0	0.1	GO:0098847	single-stranded telomeric DNA binding(GO:0043047) sequence-specific single stranded DNA binding(GO:0098847)
0.0	0.1	GO:0032454	histone demethylase activity (H3-K9 specific)(GO:0032454)
0.0	0.1	GO:0048156	tau protein binding(GO:0048156)
0.0	0.2	GO:0003688	DNA replication origin binding(GO:0003688)
0.0	0.2	GO:0080025	phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.0	0.2	GO:0005522	profilin binding(GO:0005522)
0.0	0.4	GO:0043027	cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.0	0.2	GO:0004691	cAMP-dependent protein kinase activity(GO:0004691)
0.0	0.2	GO:0050733	RS domain binding(GO:0050733)
0.0	0.2	GO:0015347	sodium-independent organic anion transmembrane transporter activity(GO:0015347)
0.0	0.4	GO:0005528	macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.0	0.1	GO:0070492	oligosaccharide binding(GO:0070492)
0.0	0.2	GO:0005388	calcium-transporting ATPase activity(GO:0005388)
0.0	0.1	GO:0042910	xenobiotic-transporting ATPase activity(GO:0008559) xenobiotic transporter activity(GO:0042910)
0.0	0.2	GO:0050664	superoxide-generating NADPH oxidase activity(GO:0016175) oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor(GO:0050664)
0.0	0.1	GO:0000064	L-ornithine transmembrane transporter activity(GO:0000064)
0.0	0.3	GO:0046875	ephrin receptor binding(GO:0046875)
0.0	0.1	GO:0043539	protein serine/threonine kinase activator activity(GO:0043539)
0.0	0.3	GO:0005547	phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.0	0.2	GO:0042043	neurexin family protein binding(GO:0042043)
0.0	0.2	GO:0008889	glycerophosphodiester phosphodiesterase activity(GO:0008889)
0.0	0.1	GO:0004311	farnesyltranstransferase activity(GO:0004311)
0.0	0.1	GO:0005436	sodium:phosphate symporter activity(GO:0005436)
0.0	0.2	GO:0005092	GDP-dissociation inhibitor activity(GO:0005092)
0.0	0.1	GO:0050815	phosphoserine binding(GO:0050815)
0.0	0.0	GO:0031434	mitogen-activated protein kinase kinase binding(GO:0031434)
0.0	0.1	GO:0016174	NAD(P)H oxidase activity(GO:0016174)
0.0	0.1	GO:0019531	oxalate transmembrane transporter activity(GO:0019531)
0.0	0.1	GO:0055103	ligase regulator activity(GO:0055103) ubiquitin-protein transferase regulator activity(GO:0055106)
0.0	0.1	GO:0008420	CTD phosphatase activity(GO:0008420)
0.0	0.1	GO:0008486	diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486)
0.0	0.3	GO:0004065	arylsulfatase activity(GO:0004065)
0.0	0.2	GO:0008171	O-methyltransferase activity(GO:0008171)
0.0	0.1	GO:0004459	L-lactate dehydrogenase activity(GO:0004459)
0.0	0.0	GO:0015272	ATP-activated inward rectifier potassium channel activity(GO:0015272)
0.0	0.1	GO:0008174	mRNA methyltransferase activity(GO:0008174)
0.0	0.1	GO:0030676	Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0	0.0	GO:0008192	RNA guanylyltransferase activity(GO:0008192)
0.0	0.0	GO:0015440	oligopeptide-transporting ATPase activity(GO:0015421) peptide-transporting ATPase activity(GO:0015440)
0.0	0.0	GO:0031685	adenosine receptor binding(GO:0031685)
0.0	0.2	GO:0016922	ligand-dependent nuclear receptor binding(GO:0016922)
0.0	0.1	GO:0005521	lamin binding(GO:0005521)
0.0	0.3	GO:0030742	GTP-dependent protein binding(GO:0030742)
0.0	0.5	GO:0035064	methylated histone binding(GO:0035064)
0.0	0.1	GO:0043142	single-stranded DNA-dependent ATPase activity(GO:0043142)
0.0	0.1	GO:0032137	guanine/thymine mispair binding(GO:0032137)
0.0	0.1	GO:0030911	TPR domain binding(GO:0030911)
0.0	0.1	GO:0030368	interleukin-17 receptor activity(GO:0030368)
0.0	0.1	GO:0004659	prenyltransferase activity(GO:0004659)
0.0	0.1	GO:0016882	cyclo-ligase activity(GO:0016882)
0.0	0.1	GO:0004563	beta-N-acetylhexosaminidase activity(GO:0004563)
0.0	0.0	GO:0030881	beta-2-microglobulin binding(GO:0030881)
0.0	0.2	GO:0004726	non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.0	0.1	GO:0015379	potassium:chloride symporter activity(GO:0015379)
0.0	0.1	GO:0017176	phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.0	0.1	GO:0000739	obsolete DNA strand annealing activity(GO:0000739)
0.0	1.4	GO:0004221	obsolete ubiquitin thiolesterase activity(GO:0004221)
0.0	0.0	GO:0019958	C-X-C chemokine binding(GO:0019958) interleukin-8 binding(GO:0019959)
0.0	0.1	GO:0008109	N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109)
0.0	0.1	GO:0031210	phosphatidylcholine binding(GO:0031210)
0.0	0.1	GO:0003873	6-phosphofructo-2-kinase activity(GO:0003873)
0.0	0.1	GO:0034713	type I transforming growth factor beta receptor binding(GO:0034713)
0.0	0.1	GO:0004677	DNA-dependent protein kinase activity(GO:0004677)
0.0	0.1	GO:0070513	death domain binding(GO:0070513)
0.0	0.1	GO:0004706	JUN kinase kinase kinase activity(GO:0004706)
0.0	0.0	GO:0015252	hydrogen ion channel activity(GO:0015252)
0.0	0.1	GO:0005375	copper ion transmembrane transporter activity(GO:0005375)
0.0	0.2	GO:0017075	syntaxin-1 binding(GO:0017075)
0.0	0.7	GO:0003725	double-stranded RNA binding(GO:0003725)
0.0	0.0	GO:0001846	opsonin binding(GO:0001846)
0.0	0.0	GO:0005219	ryanodine-sensitive calcium-release channel activity(GO:0005219)
0.0	0.1	GO:0070097	delta-catenin binding(GO:0070097)
0.0	0.6	GO:0003823	antigen binding(GO:0003823)
0.0	0.0	GO:0004457	lactate dehydrogenase activity(GO:0004457)
0.0	1.7	GO:0017124	SH3 domain binding(GO:0017124)
0.0	0.1	GO:0003886	DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.0	0.1	GO:0042288	MHC class I protein binding(GO:0042288)
0.0	0.1	GO:0016149	translation release factor activity, codon specific(GO:0016149)
0.0	0.2	GO:0042923	neuropeptide binding(GO:0042923)
0.0	0.1	GO:0004652	polynucleotide adenylyltransferase activity(GO:0004652)
0.0	0.0	GO:0004946	bombesin receptor activity(GO:0004946)
0.0	0.1	GO:0030229	very-low-density lipoprotein particle receptor activity(GO:0030229)
0.0	0.1	GO:0051766	inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440) inositol trisphosphate kinase activity(GO:0051766)
0.0	0.2	GO:0050700	CARD domain binding(GO:0050700)
0.0	0.4	GO:0070003	threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.0	0.1	GO:0030292	protein tyrosine kinase inhibitor activity(GO:0030292)
0.0	0.2	GO:0030276	clathrin binding(GO:0030276)
0.0	0.0	GO:0000268	peroxisome targeting sequence binding(GO:0000268)
0.0	0.1	GO:0005049	nuclear export signal receptor activity(GO:0005049)
0.0	0.1	GO:0016774	phosphotransferase activity, carboxyl group as acceptor(GO:0016774)
0.0	0.1	GO:0042162	telomeric DNA binding(GO:0042162)
0.0	0.2	GO:0035251	UDP-glucosyltransferase activity(GO:0035251)
0.0	0.1	GO:0004127	cytidylate kinase activity(GO:0004127)
0.0	0.2	GO:0004016	adenylate cyclase activity(GO:0004016)
0.0	0.1	GO:0000405	bubble DNA binding(GO:0000405)
0.0	0.1	GO:0016308	1-phosphatidylinositol-4-phosphate 5-kinase activity(GO:0016308)
0.0	0.1	GO:0004449	isocitrate dehydrogenase (NAD+) activity(GO:0004449)
0.0	0.0	GO:0060228	phosphatidylcholine-sterol O-acyltransferase activator activity(GO:0060228)
0.0	0.3	GO:0048487	beta-tubulin binding(GO:0048487)
0.0	0.1	GO:0004865	protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.0	0.1	GO:0004047	aminomethyltransferase activity(GO:0004047)
0.0	0.1	GO:0008536	Ran GTPase binding(GO:0008536)
0.0	0.1	GO:0008494	translation activator activity(GO:0008494)
0.0	0.1	GO:0030306	ADP-ribosylation factor binding(GO:0030306)
0.0	0.1	GO:0001727	lipid kinase activity(GO:0001727)
0.0	0.2	GO:0005031	tumor necrosis factor-activated receptor activity(GO:0005031)
0.0	0.1	GO:0003720	telomerase activity(GO:0003720) RNA-directed DNA polymerase activity(GO:0003964)
0.0	0.1	GO:0017159	pantetheine hydrolase activity(GO:0017159)
0.0	0.3	GO:0003755	peptidyl-prolyl cis-trans isomerase activity(GO:0003755)
0.0	0.3	GO:0008601	protein phosphatase type 2A regulator activity(GO:0008601)
0.0	0.1	GO:0008821	crossover junction endodeoxyribonuclease activity(GO:0008821)
0.0	0.2	GO:0043022	ribosome binding(GO:0043022)
0.0	0.1	GO:0043425	bHLH transcription factor binding(GO:0043425)
0.0	0.0	GO:0004999	vasoactive intestinal polypeptide receptor activity(GO:0004999)
0.0	0.1	GO:0004814	arginine-tRNA ligase activity(GO:0004814)
0.0	0.3	GO:0004889	acetylcholine-activated cation-selective channel activity(GO:0004889)
0.0	0.1	GO:0003988	acetyl-CoA C-acyltransferase activity(GO:0003988)
0.0	0.0	GO:0070653	high-density lipoprotein particle receptor binding(GO:0070653)
0.0	0.1	GO:0004663	Rab geranylgeranyltransferase activity(GO:0004663)
0.0	0.1	GO:0019788	NEDD8 transferase activity(GO:0019788)
0.0	0.1	GO:0008048	calcium sensitive guanylate cyclase activator activity(GO:0008048)
0.0	0.1	GO:0004340	glucokinase activity(GO:0004340)
0.0	0.1	GO:0004994	somatostatin receptor activity(GO:0004994)
0.0	0.1	GO:0015321	sodium-dependent phosphate transmembrane transporter activity(GO:0015321)
0.0	0.1	GO:0015385	sodium:proton antiporter activity(GO:0015385)
0.0	0.2	GO:0008239	dipeptidyl-peptidase activity(GO:0008239)
0.0	0.4	GO:0004693	cyclin-dependent protein serine/threonine kinase activity(GO:0004693) cyclin-dependent protein kinase activity(GO:0097472)
0.0	0.5	GO:0003697	single-stranded DNA binding(GO:0003697)
0.0	0.1	GO:0004035	alkaline phosphatase activity(GO:0004035)
0.0	0.0	GO:0004949	cannabinoid receptor activity(GO:0004949)
0.0	0.4	GO:0019003	GDP binding(GO:0019003)
0.0	0.0	GO:0016721	superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
0.0	0.0	GO:0016728	ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
0.0	0.0	GO:0004967	glucagon receptor activity(GO:0004967)
0.0	0.1	GO:0004017	adenylate kinase activity(GO:0004017)
0.0	0.1	GO:0061630	ubiquitin-ubiquitin ligase activity(GO:0034450) ubiquitin protein ligase activity(GO:0061630) ubiquitin-like protein ligase activity(GO:0061659)
0.0	0.1	GO:0017127	cholesterol transporter activity(GO:0017127)
0.0	0.4	GO:0001104	RNA polymerase II transcription cofactor activity(GO:0001104)
0.0	0.2	GO:0005246	calcium channel regulator activity(GO:0005246)
0.0	0.1	GO:0016997	exo-alpha-sialidase activity(GO:0004308) alpha-sialidase activity(GO:0016997)
0.0	0.1	GO:0043014	alpha-tubulin binding(GO:0043014)
0.0	0.0	GO:0030023	extracellular matrix constituent conferring elasticity(GO:0030023) structural molecule activity conferring elasticity(GO:0097493)
0.0	0.1	GO:0004169	dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.0	0.5	GO:0008138	protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.0	0.1	GO:0004427	inorganic diphosphatase activity(GO:0004427)
0.0	0.0	GO:0070215	obsolete MDM2 binding(GO:0070215)
0.0	0.0	GO:0031849	olfactory receptor binding(GO:0031849)
0.0	0.1	GO:0070579	methylcytosine dioxygenase activity(GO:0070579)
0.0	0.2	GO:0016892	endoribonuclease activity, producing 3'-phosphomonoesters(GO:0016892)
0.0	0.1	GO:0017025	TBP-class protein binding(GO:0017025)
0.0	0.1	GO:0015467	G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.0	0.0	GO:0032453	histone demethylase activity (H3-K4 specific)(GO:0032453) histone demethylase activity (H3-dimethyl-K4 specific)(GO:0034648)
0.0	0.1	GO:0051636	obsolete Gram-negative bacterial cell surface binding(GO:0051636)
0.0	0.1	GO:0060590	ATPase regulator activity(GO:0060590)
0.0	0.0	GO:0052658	inositol-1,4,5-trisphosphate 5-phosphatase activity(GO:0052658) inositol-1,3,4,5-tetrakisphosphate 5-phosphatase activity(GO:0052659)
0.0	0.2	GO:0004683	calmodulin-dependent protein kinase activity(GO:0004683)
0.0	0.1	GO:0016884	carbon-nitrogen ligase activity, with glutamine as amido-N-donor(GO:0016884)
0.0	0.1	GO:0051787	misfolded protein binding(GO:0051787)
0.0	0.4	GO:0004722	protein serine/threonine phosphatase activity(GO:0004722)
0.0	0.1	GO:0030983	mismatched DNA binding(GO:0030983)
0.0	0.3	GO:0005544	calcium-dependent phospholipid binding(GO:0005544)
0.0	0.1	GO:0004550	nucleoside diphosphate kinase activity(GO:0004550)
0.0	0.1	GO:0008195	phosphatidate phosphatase activity(GO:0008195)
0.0	0.0	GO:0048495	Roundabout binding(GO:0048495)
0.0	0.1	GO:0016423	tRNA (guanine) methyltransferase activity(GO:0016423)
0.0	0.0	GO:0015194	L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.0	0.3	GO:0019205	nucleobase-containing compound kinase activity(GO:0019205)
0.0	0.6	GO:0004197	cysteine-type endopeptidase activity(GO:0004197)
0.0	0.1	GO:0016634	oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor(GO:0016634)
0.0	0.1	GO:0004767	sphingomyelin phosphodiesterase activity(GO:0004767)
0.0	0.0	GO:0016286	small conductance calcium-activated potassium channel activity(GO:0016286)
0.0	0.1	GO:0070567	cytidylyltransferase activity(GO:0070567)
0.0	0.2	GO:0004089	carbonate dehydratase activity(GO:0004089)
0.0	0.0	GO:0004952	dopamine neurotransmitter receptor activity(GO:0004952)
0.0	0.0	GO:0004582	dolichyl-phosphate beta-D-mannosyltransferase activity(GO:0004582)
0.0	0.0	GO:0047894	flavonol 3-sulfotransferase activity(GO:0047894)
0.0	0.1	GO:0016778	diphosphotransferase activity(GO:0016778)
0.0	0.2	GO:0003746	translation elongation factor activity(GO:0003746)
0.0	0.3	GO:0003678	DNA helicase activity(GO:0003678)
0.0	0.2	GO:0046933	proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.0	0.0	GO:0044769	ATPase activity, coupled to transmembrane movement of ions, rotational mechanism(GO:0044769)
0.0	0.0	GO:0031177	phosphopantetheine binding(GO:0031177)
0.0	0.1	GO:0030553	cGMP binding(GO:0030553)
0.0	0.1	GO:0031996	thioesterase binding(GO:0031996)
0.0	0.0	GO:0004704	NF-kappaB-inducing kinase activity(GO:0004704)
0.0	0.0	GO:0015278	calcium-release channel activity(GO:0015278) ligand-gated calcium channel activity(GO:0099604)
0.0	0.0	GO:0003747	translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079)
0.0	0.0	GO:0005143	interleukin-12 receptor binding(GO:0005143)
0.0	0.0	GO:0016362	activin receptor activity, type II(GO:0016362)
0.0	0.0	GO:0019166	trans-2-enoyl-CoA reductase (NADPH) activity(GO:0019166)
0.0	0.1	GO:0003756	protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864)
0.0	0.1	GO:0005041	low-density lipoprotein receptor activity(GO:0005041)
0.0	0.0	GO:0016748	succinyltransferase activity(GO:0016748)
0.0	0.1	GO:0015185	gamma-aminobutyric acid transmembrane transporter activity(GO:0015185)
0.0	0.0	GO:0017081	chloride channel regulator activity(GO:0017081)
0.0	0.1	GO:0042834	peptidoglycan binding(GO:0042834)
0.0	0.1	GO:0051721	protein phosphatase 2A binding(GO:0051721)
0.0	0.0	GO:0010485	H4 histone acetyltransferase activity(GO:0010485)
0.0	0.1	GO:0001848	complement binding(GO:0001848)
0.0	0.0	GO:0003917	DNA topoisomerase type I activity(GO:0003917)
0.0	0.1	GO:0003711	obsolete transcription elongation regulator activity(GO:0003711)
0.0	0.0	GO:0017089	glycolipid transporter activity(GO:0017089)
0.0	0.0	GO:0016776	phosphotransferase activity, phosphate group as acceptor(GO:0016776)
0.0	0.1	GO:0032395	MHC class II receptor activity(GO:0032395)
0.0	0.1	GO:0016833	oxo-acid-lyase activity(GO:0016833)
0.0	0.0	GO:0047631	ADP-ribose diphosphatase activity(GO:0047631)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.1	PID LYMPH ANGIOGENESIS PATHWAY	VEGFR3 signaling in lymphatic endothelium
0.1	1.7	PID TCR JNK PATHWAY	JNK signaling in the CD4+ TCR pathway
0.1	1.0	SA PTEN PATHWAY	PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.1	2.6	PID EPHRINB REV PATHWAY	Ephrin B reverse signaling
0.1	4.5	PID TCR PATHWAY	TCR signaling in naïve CD4+ T cells
0.1	1.2	SA MMP CYTOKINE CONNECTION	Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.1	0.6	SA FAS SIGNALING	The TNF-type receptor Fas induces apoptosis on ligand binding.
0.1	1.7	PID IL8 CXCR2 PATHWAY	IL8- and CXCR2-mediated signaling events
0.1	0.6	ST INTERFERON GAMMA PATHWAY	Interferon gamma pathway.
0.1	2.3	PID NFAT TFPATHWAY	Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.1	0.8	PID PI3KCI PATHWAY	Class I PI3K signaling events
0.1	1.7	PID TXA2PATHWAY	Thromboxane A2 receptor signaling
0.1	1.3	PID ERBB1 INTERNALIZATION PATHWAY	Internalization of ErbB1
0.0	1.5	PID BCR 5PATHWAY	BCR signaling pathway
0.0	1.8	PID AR TF PATHWAY	Regulation of Androgen receptor activity
0.0	0.2	PID CD8 TCR PATHWAY	TCR signaling in naïve CD8+ T cells
0.0	0.9	PID CDC42 REG PATHWAY	Regulation of CDC42 activity
0.0	0.0	PID CXCR3 PATHWAY	CXCR3-mediated signaling events
0.0	0.1	PID TCR RAS PATHWAY	Ras signaling in the CD4+ TCR pathway
0.0	0.2	ST PAC1 RECEPTOR PATHWAY	PAC1 Receptor Pathway
0.0	0.8	PID CASPASE PATHWAY	Caspase cascade in apoptosis
0.0	0.1	PID RANBP2 PATHWAY	Sumoylation by RanBP2 regulates transcriptional repression
0.0	0.2	PID ANTHRAX PATHWAY	Cellular roles of Anthrax toxin
0.0	0.5	PID HIV NEF PATHWAY	HIV-1 Nef: Negative effector of Fas and TNF-alpha
0.0	0.2	PID IL2 1PATHWAY	IL2-mediated signaling events
0.0	0.3	PID IL12 STAT4 PATHWAY	IL12 signaling mediated by STAT4
0.0	0.5	PID MYC PATHWAY	C-MYC pathway
0.0	0.3	PID GMCSF PATHWAY	GMCSF-mediated signaling events
0.0	0.0	SIG PIP3 SIGNALING IN B LYMPHOCYTES	Genes related to PIP3 signaling in B lymphocytes
0.0	0.3	PID IL2 STAT5 PATHWAY	IL2 signaling events mediated by STAT5
0.0	0.3	PID FCER1 PATHWAY	Fc-epsilon receptor I signaling in mast cells
0.0	0.7	PID RAC1 PATHWAY	RAC1 signaling pathway
0.0	0.1	PID CD40 PATHWAY	CD40/CD40L signaling
0.0	0.2	PID P38 ALPHA BETA PATHWAY	Regulation of p38-alpha and p38-beta
0.0	0.3	PID IFNG PATHWAY	IFN-gamma pathway
0.0	0.0	ST DIFFERENTIATION PATHWAY IN PC12 CELLS	Differentiation Pathway in PC12 Cells; this is a specific case of PAC1 Receptor Pathway.
0.0	0.0	ST GA12 PATHWAY	G alpha 12 Pathway
0.0	0.1	PID THROMBIN PAR4 PATHWAY	PAR4-mediated thrombin signaling events
0.0	0.4	PID IL12 2PATHWAY	IL12-mediated signaling events
0.0	0.4	PID INSULIN GLUCOSE PATHWAY	Insulin-mediated glucose transport
0.0	0.2	PID BETA CATENIN DEG PATHWAY	Degradation of beta catenin
0.0	0.3	PID RAS PATHWAY	Regulation of Ras family activation
0.0	0.2	ST PHOSPHOINOSITIDE 3 KINASE PATHWAY	PI3K Pathway
0.0	0.2	PID WNT NONCANONICAL PATHWAY	Noncanonical Wnt signaling pathway
0.0	0.2	PID LPA4 PATHWAY	LPA4-mediated signaling events
0.0	0.3	PID ARF6 PATHWAY	Arf6 signaling events
0.0	0.2	PID NFAT 3PATHWAY	Role of Calcineurin-dependent NFAT signaling in lymphocytes
0.0	0.1	PID NFKAPPAB CANONICAL PATHWAY	Canonical NF-kappaB pathway
0.0	0.1	ST TUMOR NECROSIS FACTOR PATHWAY	Tumor Necrosis Factor Pathway.
0.0	0.1	SA G1 AND S PHASES	Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition.
0.0	0.0	PID ARF6 DOWNSTREAM PATHWAY	Arf6 downstream pathway
0.0	0.5	PID P53 REGULATION PATHWAY	p53 pathway
0.0	0.0	PID EPO PATHWAY	EPO signaling pathway
0.0	0.4	PID IL4 2PATHWAY	IL4-mediated signaling events
0.0	0.1	PID THROMBIN PAR1 PATHWAY	PAR1-mediated thrombin signaling events
0.0	0.4	PID AURORA B PATHWAY	Aurora B signaling
0.0	0.1	PID ERB GENOMIC PATHWAY	Validated nuclear estrogen receptor beta network
0.0	0.0	ST JAK STAT PATHWAY	Jak-STAT Pathway
0.0	0.3	PID CONE PATHWAY	Visual signal transduction: Cones
0.0	0.2	PID INTEGRIN A4B1 PATHWAY	Alpha4 beta1 integrin signaling events
0.0	0.4	PID LKB1 PATHWAY	LKB1 signaling events
0.0	0.1	PID P38 ALPHA BETA DOWNSTREAM PATHWAY	Signaling mediated by p38-alpha and p38-beta
0.0	0.0	PID ERBB NETWORK PATHWAY	ErbB receptor signaling network
0.0	0.1	SIG CD40PATHWAYMAP	Genes related to CD40 signaling
0.0	0.1	PID HDAC CLASSII PATHWAY	Signaling events mediated by HDAC Class II

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	0.7	REACTOME BINDING AND ENTRY OF HIV VIRION	Genes involved in Binding and entry of HIV virion
0.2	2.1	REACTOME GENERATION OF SECOND MESSENGER MOLECULES	Genes involved in Generation of second messenger molecules
0.1	1.0	REACTOME CD28 DEPENDENT VAV1 PATHWAY	Genes involved in CD28 dependent Vav1 pathway
0.1	1.6	REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS	Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.1	2.5	REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS	Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.1	0.2	REACTOME AUTODEGRADATION OF THE E3 UBIQUITIN LIGASE COP1	Genes involved in Autodegradation of the E3 ubiquitin ligase COP1
0.1	1.5	REACTOME N GLYCAN ANTENNAE ELONGATION IN THE MEDIAL TRANS GOLGI	Genes involved in N-glycan antennae elongation in the medial/trans-Golgi
0.1	0.6	REACTOME ACTIVATION OF RAC	Genes involved in Activation of Rac
0.1	1.3	REACTOME EFFECTS OF PIP2 HYDROLYSIS	Genes involved in Effects of PIP2 hydrolysis
0.1	0.1	REACTOME ENDOSOMAL VACUOLAR PATHWAY	Genes involved in Endosomal/Vacuolar pathway
0.1	0.9	REACTOME CTLA4 INHIBITORY SIGNALING	Genes involved in CTLA4 inhibitory signaling
0.1	0.7	REACTOME REGULATION OF IFNG SIGNALING	Genes involved in Regulation of IFNG signaling
0.1	1.5	REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE	Genes involved in Synthesis of PIPs at the plasma membrane
0.1	0.4	REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS	Genes involved in Signal regulatory protein (SIRP) family interactions
0.1	0.8	REACTOME COSTIMULATION BY THE CD28 FAMILY	Genes involved in Costimulation by the CD28 family
0.1	1.1	REACTOME THE ROLE OF NEF IN HIV1 REPLICATION AND DISEASE PATHOGENESIS	Genes involved in The role of Nef in HIV-1 replication and disease pathogenesis
0.1	0.8	REACTOME DARPP 32 EVENTS	Genes involved in DARPP-32 events
0.0	0.4	REACTOME RAF MAP KINASE CASCADE	Genes involved in RAF/MAP kinase cascade
0.0	0.1	REACTOME REGULATION OF SIGNALING BY CBL	Genes involved in Regulation of signaling by CBL
0.0	0.5	REACTOME GRB2 SOS PROVIDES LINKAGE TO MAPK SIGNALING FOR INTERGRINS	Genes involved in GRB2:SOS provides linkage to MAPK signaling for Intergrins
0.0	1.3	REACTOME INTERFERON GAMMA SIGNALING	Genes involved in Interferon gamma signaling
0.0	0.4	REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE	Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.0	0.7	REACTOME CHONDROITIN SULFATE BIOSYNTHESIS	Genes involved in Chondroitin sulfate biosynthesis
0.0	2.0	REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL	Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0	0.5	REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS	Genes involved in Extrinsic Pathway for Apoptosis
0.0	0.5	REACTOME IL RECEPTOR SHC SIGNALING	Genes involved in Interleukin receptor SHC signaling
0.0	1.0	REACTOME REGULATION OF BETA CELL DEVELOPMENT	Genes involved in Regulation of beta-cell development
0.0	0.3	REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING	Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
0.0	0.1	REACTOME IL 3 5 AND GM CSF SIGNALING	Genes involved in Interleukin-3, 5 and GM-CSF signaling
0.0	0.2	REACTOME IRAK1 RECRUITS IKK COMPLEX	Genes involved in IRAK1 recruits IKK complex
0.0	0.7	REACTOME POST NMDA RECEPTOR ACTIVATION EVENTS	Genes involved in Post NMDA receptor activation events
0.0	0.3	REACTOME DOWNSTREAM TCR SIGNALING	Genes involved in Downstream TCR signaling
0.0	0.1	REACTOME SPRY REGULATION OF FGF SIGNALING	Genes involved in Spry regulation of FGF signaling
0.0	0.6	REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA	Genes involved in Circadian Repression of Expression by REV-ERBA
0.0	0.2	REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS	Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0	0.4	REACTOME ASSOCIATION OF LICENSING FACTORS WITH THE PRE REPLICATIVE COMPLEX	Genes involved in Association of licensing factors with the pre-replicative complex
0.0	0.2	REACTOME PKA MEDIATED PHOSPHORYLATION OF CREB	Genes involved in PKA-mediated phosphorylation of CREB
0.0	0.1	REACTOME IL 7 SIGNALING	Genes involved in Interleukin-7 signaling
0.0	0.6	REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE	Genes involved in Sema4D induced cell migration and growth-cone collapse
0.0	0.4	REACTOME CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE	Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
0.0	0.3	REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING	Genes involved in Formation of ATP by chemiosmotic coupling
0.0	0.5	REACTOME PRE NOTCH TRANSCRIPTION AND TRANSLATION	Genes involved in Pre-NOTCH Transcription and Translation
0.0	0.4	REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES	Genes involved in Cytosolic sulfonation of small molecules
0.0	0.5	REACTOME NOD1 2 SIGNALING PATHWAY	Genes involved in NOD1/2 Signaling Pathway
0.0	0.7	REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION	Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.0	0.0	REACTOME TRAF6 MEDIATED IRF7 ACTIVATION	Genes involved in TRAF6 mediated IRF7 activation
0.0	0.2	REACTOME ASSEMBLY OF THE PRE REPLICATIVE COMPLEX	Genes involved in Assembly of the pre-replicative complex
0.0	0.0	REACTOME SHC MEDIATED SIGNALLING	Genes involved in SHC-mediated signalling
0.0	0.4	REACTOME NUCLEOTIDE LIKE PURINERGIC RECEPTORS	Genes involved in Nucleotide-like (purinergic) receptors
0.0	0.0	REACTOME GPVI MEDIATED ACTIVATION CASCADE	Genes involved in GPVI-mediated activation cascade
0.0	0.0	REACTOME SHC RELATED EVENTS	Genes involved in SHC-related events
0.0	0.1	REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION	Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.0	0.2	REACTOME COMMON PATHWAY	Genes involved in Common Pathway
0.0	0.7	REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS	Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.0	0.3	REACTOME TRANSPORT TO THE GOLGI AND SUBSEQUENT MODIFICATION	Genes involved in Transport to the Golgi and subsequent modification
0.0	0.4	REACTOME KERATAN SULFATE BIOSYNTHESIS	Genes involved in Keratan sulfate biosynthesis
0.0	0.8	REACTOME GLYCOSPHINGOLIPID METABOLISM	Genes involved in Glycosphingolipid metabolism
0.0	1.0	REACTOME ACTIVATION OF NF KAPPAB IN B CELLS	Genes involved in Activation of NF-kappaB in B Cells
0.0	0.2	REACTOME HIGHLY CALCIUM PERMEABLE POSTSYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS	Genes involved in Highly calcium permeable postsynaptic nicotinic acetylcholine receptors
0.0	0.4	REACTOME CHOLESTEROL BIOSYNTHESIS	Genes involved in Cholesterol biosynthesis
0.0	0.0	REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING	Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.0	0.1	REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS	Genes involved in Membrane binding and targetting of GAG proteins
0.0	0.2	REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION	Genes involved in GABA synthesis, release, reuptake and degradation
0.0	0.3	REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI	Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.0	0.5	REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS	Genes involved in Apoptotic cleavage of cellular proteins
0.0	0.2	REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION	Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.0	0.3	REACTOME INTRINSIC PATHWAY	Genes involved in Intrinsic Pathway
0.0	0.2	REACTOME PURINE SALVAGE	Genes involved in Purine salvage
0.0	0.2	REACTOME METABOLISM OF PORPHYRINS	Genes involved in Metabolism of porphyrins
0.0	1.1	REACTOME RESPIRATORY ELECTRON TRANSPORT ATP SYNTHESIS BY CHEMIOSMOTIC COUPLING AND HEAT PRODUCTION BY UNCOUPLING PROTEINS	Genes involved in Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins.
0.0	0.2	REACTOME TRAF6 MEDIATED NFKB ACTIVATION	Genes involved in TRAF6 mediated NF-kB activation
0.0	0.1	REACTOME DSCAM INTERACTIONS	Genes involved in DSCAM interactions
0.0	0.2	REACTOME TRANSPORT OF ORGANIC ANIONS	Genes involved in Transport of organic anions
0.0	0.2	REACTOME CITRIC ACID CYCLE TCA CYCLE	Genes involved in Citric acid cycle (TCA cycle)
0.0	0.1	REACTOME SIGNALING BY WNT	Genes involved in Signaling by Wnt
0.0	0.2	REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS	Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.0	0.7	REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES	Genes involved in Chemokine receptors bind chemokines
0.0	0.2	REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS	Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.0	0.2	REACTOME NUCLEOTIDE BINDING DOMAIN LEUCINE RICH REPEAT CONTAINING RECEPTOR NLR SIGNALING PATHWAYS	Genes involved in Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways
0.0	0.2	REACTOME AMINE DERIVED HORMONES	Genes involved in Amine-derived hormones
0.0	0.2	REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT	Genes involved in Chylomicron-mediated lipid transport
0.0	0.0	REACTOME PROSTACYCLIN SIGNALLING THROUGH PROSTACYCLIN RECEPTOR	Genes involved in Prostacyclin signalling through prostacyclin receptor
0.0	0.1	REACTOME AKT PHOSPHORYLATES TARGETS IN THE CYTOSOL	Genes involved in AKT phosphorylates targets in the cytosol
0.0	0.0	REACTOME LYSOSOME VESICLE BIOGENESIS	Genes involved in Lysosome Vesicle Biogenesis
0.0	0.2	REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GLP1	Genes involved in Synthesis, Secretion, and Inactivation of Glucagon-like Peptide-1 (GLP-1)
0.0	0.0	REACTOME INTERACTIONS OF VPR WITH HOST CELLULAR PROTEINS	Genes involved in Interactions of Vpr with host cellular proteins
0.0	0.2	REACTOME INSULIN SYNTHESIS AND PROCESSING	Genes involved in Insulin Synthesis and Processing
0.0	0.6	REACTOME METABOLISM OF NON CODING RNA	Genes involved in Metabolism of non-coding RNA
0.0	0.5	REACTOME VOLTAGE GATED POTASSIUM CHANNELS	Genes involved in Voltage gated Potassium channels
0.0	0.0	REACTOME MRNA CAPPING	Genes involved in mRNA Capping
0.0	0.2	REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING	Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.0	0.1	REACTOME G PROTEIN ACTIVATION	Genes involved in G-protein activation
0.0	0.1	REACTOME PRE NOTCH PROCESSING IN GOLGI	Genes involved in Pre-NOTCH Processing in Golgi
0.0	0.0	REACTOME S PHASE	Genes involved in S Phase
0.0	0.3	REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES	Genes involved in Antiviral mechanism by IFN-stimulated genes
0.0	0.0	REACTOME CDK MEDIATED PHOSPHORYLATION AND REMOVAL OF CDC6	Genes involved in CDK-mediated phosphorylation and removal of Cdc6
0.0	0.1	REACTOME ABACAVIR TRANSPORT AND METABOLISM	Genes involved in Abacavir transport and metabolism
0.0	0.1	REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE	Genes involved in Glutamate Neurotransmitter Release Cycle
0.0	1.1	REACTOME MRNA SPLICING	Genes involved in mRNA Splicing
0.0	0.0	REACTOME HS GAG DEGRADATION	Genes involved in HS-GAG degradation
0.0	0.2	REACTOME METAL ION SLC TRANSPORTERS	Genes involved in Metal ion SLC transporters
0.0	0.1	REACTOME ALPHA LINOLENIC ACID ALA METABOLISM	Genes involved in alpha-linolenic acid (ALA) metabolism
0.0	0.1	REACTOME SYNTHESIS OF PE	Genes involved in Synthesis of PE
0.0	0.1	REACTOME ER PHAGOSOME PATHWAY	Genes involved in ER-Phagosome pathway
0.0	0.1	REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE	Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.0	0.0	REACTOME INTEGRATION OF PROVIRUS	Genes involved in Integration of provirus
0.0	0.0	REACTOME REGULATION OF IFNA SIGNALING	Genes involved in Regulation of IFNA signaling
0.0	0.0	REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS	Genes involved in Elevation of cytosolic Ca2+ levels
0.0	0.1	REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION	Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.0	0.1	REACTOME COPI MEDIATED TRANSPORT	Genes involved in COPI Mediated Transport
0.0	1.0	REACTOME SIGNALING BY RHO GTPASES	Genes involved in Signaling by Rho GTPases
0.0	0.0	REACTOME PROCESSING OF CAPPED INTRON CONTAINING PRE MRNA	Genes involved in Processing of Capped Intron-Containing Pre-mRNA
0.0	0.7	REACTOME MEIOTIC SYNAPSIS	Genes involved in Meiotic Synapsis

Results for PBX1

Z-value: 1.36

Motif logo

Transcription factors associated with PBX1

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

Activity of the PBX1 motif across conditions

Conditions sorted by the z-value of the PBX1 motif activity

Top target CREs of the motif:

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of PBX1

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category:

Gene overrepresentation in curated gene sets: canonical pathways category:

Gene overrepresentation in curated gene sets: REACTOME pathways category: