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ENCODE: H3K4me1 ChIP-Seq of primary human cells

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CREMA is a free online tool that recognizes most important transcription factors that change the chromatin state across different samples.

Results for PBX3

Z-value: 1.50

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Transcription factors associated with PBX3

Gene Symbol	Gene ID	Gene Info
PBX3 Ensembl NCBI GeneCards UniProt	ENSG00000167081.12	PBX3

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE	Gene	Distance	Association probability	Pearson corr. coef.	P-value	Plot
PBX3	chr9_128507553_128507704	1996	0.422825	-0.78	1.4e-02	Click!
PBX3	chr9_128569217_128569368	58258	0.151053	-0.77	1.5e-02	Click!
PBX3	chr9_128569608_128569759	57867	0.152131	-0.76	1.8e-02	Click!
PBX3	chr9_128507309_128507460	2240	0.394795	-0.74	2.3e-02	Click!
PBX3	chr9_128586556_128586874	40835	0.205134	0.74	2.4e-02	Click!

Activity of the PBX3 motif across conditions

Conditions sorted by the z-value of the PBX3 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE)	Target Score	Top associated gene	Gene Info	Distance of CRE to TSS	CRE/Gene association probability
chr12_46612081_46612340	0.66	SLC38A1	solute carrier family 38, member 1	49274	0.18
chr19_16478953_16479699	0.62	EPS15L1	epidermal growth factor receptor pathway substrate 15-like 1	6562	0.16
chr12_132089385_132089651	0.48	ENSG00000212154	.	56090	0.15
chr1_231749795_231749989	0.46	LINC00582	long intergenic non-protein coding RNA 582	2056	0.33
chr1_209923175_209923334	0.40	TRAF3IP3	TRAF3 interacting protein 3	6123	0.15
chr17_4407370_4407845	0.39	AC118754.4		4638	0.14
chr21_46337383_46337695	0.38	ITGB2	integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)	3231	0.13
chr9_117152080_117152353	0.38	AKNA	AT-hook transcription factor	1855	0.37
chr5_156698267_156698699	0.37	CYFIP2	cytoplasmic FMR1 interacting protein 2	2121	0.24
chr5_177665749_177666095	0.36	PHYKPL	5-phosphohydroxy-L-lysine phospho-lyase	6136	0.21
chr19_7401594_7401745	0.36	CTB-133G6.1		12179	0.16
chr18_74765525_74765769	0.35	MBP	myelin basic protein	35913	0.2
chr22_37255941_37256092	0.35	NCF4	neutrophil cytosolic factor 4, 40kDa	1014	0.44
chr1_226085113_226085288	0.35	LEFTY1	left-right determination factor 1	8354	0.12
chr15_31657045_31657355	0.34	KLF13	Kruppel-like factor 13	1157	0.65
chr3_13459136_13459287	0.34	NUP210	nucleoporin 210kDa	2598	0.34
chr8_27223358_27224128	0.34	PTK2B	protein tyrosine kinase 2 beta	14425	0.22
chr1_108383656_108383813	0.33	ENSG00000265536	.	64856	0.13
chr14_91831572_91831792	0.33	ENSG00000265856	.	31625	0.18
chr14_91882380_91882531	0.33	CCDC88C	coiled-coil domain containing 88C	1235	0.55
chr10_74089130_74089540	0.33	DNAJB12	DnaJ (Hsp40) homolog, subfamily B, member 12	15384	0.18
chr15_65185093_65185446	0.33	ENSG00000264929	.	7169	0.15
chr16_68112832_68113115	0.32	NFATC3	nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3	6274	0.11
chr11_68597072_68597223	0.32	CPT1A	carnitine palmitoyltransferase 1A (liver)	10005	0.2
chr12_42983182_42983333	0.31	PRICKLE1	prickle homolog 1 (Drosophila)	221	0.96
chr1_247554015_247554170	0.31	NLRP3	NLR family, pyrin domain containing 3	25366	0.15
chr4_36287491_36287642	0.31	DTHD1	death domain containing 1	1922	0.38
chr20_44988074_44988423	0.31	SLC35C2	solute carrier family 35 (GDP-fucose transporter), member C2	845	0.63
chr2_74432429_74432593	0.31	MTHFD2	methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase	6768	0.14
chr19_1854678_1854886	0.31	CTB-31O20.6		2384	0.13
chr2_68970790_68970944	0.30	ARHGAP25	Rho GTPase activating protein 25	8853	0.26
chr15_69084791_69085147	0.30	ENSG00000265195	.	9295	0.23
chr13_95837690_95837898	0.30	ENSG00000238463	.	24804	0.24
chr6_53202509_53202860	0.30	ELOVL5	ELOVL fatty acid elongase 5	10903	0.21
chr6_37470020_37470409	0.30	CCDC167	coiled-coil domain containing 167	2516	0.3
chrX_19818791_19819076	0.29	SH3KBP1	SH3-domain kinase binding protein 1	1064	0.67
chr2_43402387_43402951	0.29	ZFP36L2	ZFP36 ring finger protein-like 2	51079	0.14
chr7_102072492_102072712	0.29	ORAI2	ORAI calcium release-activated calcium modulator 2	951	0.34
chr2_191934456_191934744	0.29	ENSG00000231858	.	48348	0.11
chr9_92096499_92096783	0.29	SEMA4D	sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D	1836	0.41
chr20_20714651_20715009	0.29	ENSG00000264361	.	4544	0.29
chr1_207307763_207307914	0.29	C4BPA	complement component 4 binding protein, alpha	30187	0.15
chr19_50083532_50083683	0.29	NOSIP	nitric oxide synthase interacting protein	196	0.58
chr12_56536054_56536223	0.29	MYL6B	myosin, light chain 6B, alkali, smooth muscle and non-muscle	9902	0.06
chr16_21519012_21519163	0.29	ENSG00000265462	.	1631	0.33
chr9_134466441_134466779	0.29	RAPGEF1	Rap guanine nucleotide exchange factor (GEF) 1	30615	0.15
chr10_73454547_73455031	0.29	C10orf105	chromosome 10 open reading frame 105	24789	0.19
chr15_67359185_67359373	0.28	SMAD3	SMAD family member 3	1096	0.64
chr11_121290717_121290893	0.28	SORL1	sortilin-related receptor, L(DLR class) A repeats containing	32107	0.2
chr22_37256493_37256696	0.28	NCF4	neutrophil cytosolic factor 4, 40kDa	436	0.77
chr16_23846812_23846963	0.28	PRKCB	protein kinase C, beta	435	0.87
chr15_81585979_81586156	0.28	IL16	interleukin 16	3187	0.26
chr8_48512256_48512407	0.28	SPIDR	scaffolding protein involved in DNA repair	59895	0.12
chr19_47947885_47948253	0.28	MEIS3	Meis homeobox 3	25289	0.11
chr7_150148399_150148619	0.28	GIMAP8	GTPase, IMAP family member 8	791	0.61
chr7_950255_950436	0.28	ADAP1	ArfGAP with dual PH domains 1	5631	0.16
chr7_106102687_106102838	0.28	CTB-111H14.1		42523	0.2
chrX_71327974_71328129	0.27	RGAG4	retrotransposon gag domain containing 4	23627	0.15
chr3_185868368_185868519	0.27	ETV5	ets variant 5	40336	0.17
chr15_70011296_70011552	0.27	ENSG00000238870	.	11737	0.27
chr1_112059890_112060120	0.27	ADORA3	adenosine A3 receptor	13623	0.12
chr10_17272231_17272382	0.27	VIM	vimentin	302	0.5
chr21_34674475_34674626	0.27	IFNAR1	interferon (alpha, beta and omega) receptor 1	22184	0.14
chr21_47012341_47012492	0.27	SLC19A1	solute carrier family 19 (folate transporter), member 1	48091	0.13
chr1_226869309_226869761	0.27	ITPKB-IT1	ITPKB intronic transcript 1 (non-protein coding)	6767	0.22
chr16_23849905_23850213	0.27	PRKCB	protein kinase C, beta	1515	0.48
chr6_33882010_33882240	0.27	ENSG00000221697	.	85703	0.07
chr5_75679885_75680036	0.26	IQGAP2	IQ motif containing GTPase activating protein 2	19114	0.25
chr8_8937758_8938041	0.26	ENSG00000239078	.	7873	0.16
chr19_45673972_45674161	0.26	TRAPPC6A	trafficking protein particle complex 6A	7419	0.1
chr7_150284241_150284504	0.26	GIMAP4	GTPase, IMAP family member 4	19848	0.17
chr12_89637392_89637703	0.26	ENSG00000238302	.	38515	0.21
chr9_95875174_95875472	0.26	C9orf89	chromosome 9 open reading frame 89	16823	0.14
chr5_148229367_148229546	0.26	ADRB2	adrenoceptor beta 2, surface	23300	0.23
chr19_23578327_23578478	0.26	ZNF91	zinc finger protein 91	40	0.99
chr2_220075170_220075321	0.26	ZFAND2B	zinc finger, AN1-type domain 2B	2065	0.13
chr19_51614835_51615109	0.26	CTU1	cytosolic thiouridylase subunit 1	3345	0.12
chr7_5764788_5764939	0.26	RNF216-IT1	RNF216 intronic transcript 1 (non-protein coding)	44771	0.12
chr6_53158531_53158728	0.26	ENSG00000264056	.	16838	0.19
chr8_56887355_56887506	0.26	ENSG00000240905	.	5666	0.17
chr17_76128893_76129294	0.26	TMC6	transmembrane channel-like 6	605	0.58
chr7_142393843_142394165	0.26	MTRNR2L6	MT-RNR2-like 6	19900	0.21
chr8_91027854_91028058	0.26	DECR1	2,4-dienoyl CoA reductase 1, mitochondrial	14211	0.21
chr22_30383223_30383521	0.26	MTMR3	myotubularin related protein 3	16332	0.18
chr2_143899228_143899449	0.26	ARHGAP15	Rho GTPase activating protein 15	12455	0.25
chr15_93423599_93423785	0.25	CHD2	chromodomain helicase DNA binding protein 2	2834	0.25
chr22_23180915_23181197	0.25	IGLV3-7	immunoglobulin lambda variable 3-7 (pseudogene)	277	0.69
chrX_49144105_49144462	0.25	PPP1R3F	protein phosphatase 1, regulatory subunit 3F	7044	0.09
chr7_50359446_50359660	0.25	IKZF1	IKAROS family zinc finger 1 (Ikaros)	7692	0.3
chr2_28600951_28601321	0.25	FOSL2	FOS-like antigen 2	14533	0.17
chr6_37891842_37892090	0.25	ZFAND3	zinc finger, AN1-type domain 3	5769	0.23
chr4_124343671_124343822	0.25	SPRY1	sprouty homolog 1, antagonist of FGF signaling (Drosophila)	22623	0.29
chr6_53209989_53210148	0.25	ELOVL5	ELOVL fatty acid elongase 5	3519	0.27
chr6_24938013_24938250	0.25	FAM65B	family with sequence similarity 65, member B	1943	0.4
chr1_65528662_65528934	0.25	ENSG00000199135	.	4607	0.21
chr7_158333894_158334080	0.25	PTPRN2	protein tyrosine phosphatase, receptor type, N polypeptide 2	311	0.87
chr11_128437008_128437281	0.25	ETS1	v-ets avian erythroblastosis virus E26 oncogene homolog 1	20309	0.22
chr10_82286341_82286627	0.25	RP11-137H2.4		9214	0.21
chr16_3264680_3265035	0.25	OR1F1	olfactory receptor, family 1, subfamily F, member 1	10610	0.1
chr4_153556216_153556367	0.25	RP11-768B22.2		31229	0.17
chr10_7301599_7302058	0.24	SFMBT2	Scm-like with four mbt domains 2	148879	0.05
chr9_36143442_36143697	0.24	GLIPR2	GLI pathogenesis-related 2	6827	0.19
chr11_970627_970916	0.24	ENSG00000264671	.	19407	0.11
chr1_169572674_169572971	0.24	SELP	selectin P (granule membrane protein 140kDa, antigen CD62)	15635	0.19
chr2_198160878_198161163	0.24	ANKRD44-IT1	ANKRD44 intronic transcript 1 (non-protein coding)	6223	0.18
chr14_65196780_65197075	0.24	PLEKHG3	pleckstrin homology domain containing, family G (with RhoGef domain) member 3	6428	0.23
chr2_99090936_99091099	0.24	INPP4A	inositol polyphosphate-4-phosphatase, type I, 107kDa	29604	0.2
chr11_62375084_62375469	0.24	RP11-831H9.3		1643	0.14
chr12_108943808_108943959	0.24	SART3	squamous cell carcinoma antigen recognized by T cells 3	779	0.58
chr22_36845283_36845515	0.24	ENSG00000252225	.	8384	0.15
chr16_57637288_57637569	0.24	GPR56	G protein-coupled receptor 56	7136	0.16
chr11_118334021_118334172	0.24	KMT2A	lysine (K)-specific methyltransferase 2A	18450	0.1
chr11_3970595_3970888	0.24	STIM1	stromal interaction molecule 1	2168	0.29
chr3_46283606_46283757	0.24	CCR3	chemokine (C-C motif) receptor 3	191	0.95
chrX_39632433_39632734	0.24	ENSG00000264618	.	13494	0.27
chr12_94598358_94598823	0.24	RP11-74K11.2		18770	0.19
chr2_70702817_70703084	0.24	TGFA-IT1	TGFA intronic transcript 1 (non-protein coding)	7323	0.17
chr10_11185783_11186046	0.24	CELF2	CUGBP, Elav-like family member 2	21079	0.19
chr14_93124009_93124262	0.24	RIN3	Ras and Rab interactor 3	5289	0.29
chr7_128709355_128709605	0.24	ENSG00000238733	.	7895	0.17
chr4_113210653_113210866	0.24	TIFA	TRAF-interacting protein with forkhead-associated domain	3700	0.19
chr4_25856242_25856535	0.24	SEL1L3	sel-1 suppressor of lin-12-like 3 (C. elegans)	5865	0.28
chr5_75838190_75838590	0.24	IQGAP2	IQ motif containing GTPase activating protein 2	4844	0.28
chr14_99720519_99720759	0.23	AL109767.1		8646	0.22
chr22_40739144_40739395	0.23	ADSL	adenylosuccinate lyase	3238	0.24
chr12_55362221_55362689	0.23	TESPA1	thymocyte expressed, positive selection associated 1	4883	0.26
chr6_157204713_157204928	0.23	ARID1B	AT rich interactive domain 1B (SWI1-like)	17687	0.27
chr21_32549988_32550321	0.23	TIAM1	T-cell lymphoma invasion and metastasis 1	47615	0.18
chr1_101700535_101700730	0.23	RP4-575N6.4		1452	0.31
chr1_100889654_100889805	0.23	ENSG00000216067	.	45398	0.13
chr20_47489423_47489788	0.23	PREX1	phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 1	45185	0.16
chr14_93055044_93055462	0.23	RIN3	Ras and Rab interactor 3	63593	0.13
chr6_116990241_116990392	0.23	ZUFSP	zinc finger with UFM1-specific peptidase domain	359	0.86
chr2_113873143_113873294	0.23	IL1RN	interleukin 1 receptor antagonist	2252	0.23
chr17_61741988_61742139	0.23	LIMD2	LIM domain containing 2	34459	0.11
chr17_40827802_40827953	0.23	PLEKHH3	pleckstrin homology domain containing, family H (with MyTH4 domain) member 3	1092	0.28
chr1_936801_936952	0.23	HES4	hes family bHLH transcription factor 4	1324	0.24
chr8_92077318_92077469	0.23	GS1-251I9.4		4958	0.14
chr1_247171443_247171594	0.23	ZNF695	zinc finger protein 695	123	0.97
chr9_102353038_102353189	0.23	NR4A3	nuclear receptor subfamily 4, group A, member 3	231024	0.02
chr16_30915219_30915595	0.23	CTF1	cardiotrophin 1	7448	0.08
chr2_113944916_113945243	0.23	PSD4	pleckstrin and Sec7 domain containing 4	8778	0.14
chr5_118660068_118660353	0.23	TNFAIP8	tumor necrosis factor, alpha-induced protein 8	8660	0.2
chr1_27659481_27659659	0.23	ENSG00000206888	.	7860	0.12
chr4_40725932_40726083	0.23	NSUN7	NOP2/Sun domain family, member 7	25907	0.2
chr19_6710761_6710951	0.23	C3	complement component 3	9837	0.12
chr4_16214348_16214631	0.23	TAPT1	transmembrane anterior posterior transformation 1	13605	0.19
chr12_109019257_109019703	0.23	RP11-689B22.2		2983	0.18
chr1_31223327_31223571	0.23	LAPTM5	lysosomal protein transmembrane 5	7218	0.16
chr14_91834332_91834534	0.23	ENSG00000265856	.	34376	0.17
chr3_47000825_47001095	0.23	CCDC12	coiled-coil domain containing 12	17310	0.15
chr12_19638734_19639025	0.23	AEBP2	AE binding protein 2	14148	0.25
chr7_135604339_135604490	0.23	AC015987.1		6789	0.16
chr22_46636685_46636903	0.23	CDPF1	cysteine-rich, DPF motif domain containing 1	7388	0.15
chr16_81748374_81748687	0.22	PLCG2	phospholipase C, gamma 2 (phosphatidylinositol-specific)	24172	0.24
chr2_231186113_231186438	0.22	SP140L	SP140 nuclear body protein-like	5624	0.26
chr19_2608004_2608206	0.22	CTC-265F19.2		3755	0.18
chr19_914979_915242	0.22	R3HDM4	R3H domain containing 4	1870	0.15
chr6_6395826_6395997	0.22	F13A1	coagulation factor XIII, A1 polypeptide	74665	0.11
chr3_39402867_39403018	0.22	SLC25A38	solute carrier family 25, member 38	21897	0.13
chr16_84639875_84640026	0.22	COTL1	coactosin-like 1 (Dictyostelium)	11715	0.16
chr11_64625973_64626226	0.22	CDC42BPG	CDC42 binding protein kinase gamma (DMPK-like)	14058	0.09
chr7_42276890_42277078	0.22	GLI3	GLI family zinc finger 3	326	0.95
chr5_100216168_100216319	0.22	ST8SIA4	ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4	22675	0.25
chr6_137107555_137107777	0.22	MAP3K5	mitogen-activated protein kinase kinase kinase 5	5990	0.23
chr1_221242594_221242791	0.22	HLX	H2.0-like homeobox	188108	0.03
chr6_15398984_15399345	0.22	JARID2	jumonji, AT rich interactive domain 2	1925	0.43
chr15_78467078_78467229	0.22	IDH3A	isocitrate dehydrogenase 3 (NAD+) alpha	11095	0.15
chr7_42965374_42965592	0.22	PSMA2	proteasome (prosome, macropain) subunit, alpha type, 2	6290	0.2
chr6_139467698_139467849	0.22	HECA	headcase homolog (Drosophila)	11524	0.25
chr10_94674473_94674624	0.22	EXOC6	exocyst complex component 6	66271	0.12
chr11_60790247_60790506	0.22	CD6	CD6 molecule	14370	0.14
chr1_110044414_110044707	0.22	AMIGO1	adhesion molecule with Ig-like domain 1	7744	0.1
chr6_42902274_42902475	0.22	CNPY3	canopy FGF signaling regulator 3	5392	0.11
chr16_57061127_57061278	0.22	NLRC5	NLR family, CARD domain containing 5	411	0.8
chr17_54985578_54985834	0.22	TRIM25	tripartite motif containing 25	5682	0.13
chr7_144474434_144474585	0.22	TPK1	thiamin pyrophosphokinase 1	38494	0.2
chr5_140949949_140950149	0.22	CTD-2024I7.13		12171	0.11
chrX_19857997_19858148	0.22	SH3KBP1	SH3-domain kinase binding protein 1	40203	0.19
chr19_50431904_50432210	0.22	ATF5	activating transcription factor 5	98	0.81
chr10_73499533_73499684	0.22	C10orf105	chromosome 10 open reading frame 105	2027	0.34
chr22_40781657_40781809	0.22	RP5-1042K10.10		2488	0.24
chr10_5336359_5336594	0.22	AKR1C7P	aldo-keto reductase family 1, member C7, pseudogene	6043	0.22
chr6_8434992_8435322	0.22	SLC35B3	solute carrier family 35 (adenosine 3'-phospho 5'-phosphosulfate transporter), member B3	559	0.87
chr2_68966301_68966859	0.22	ARHGAP25	Rho GTPase activating protein 25	4566	0.29
chr8_126658824_126659129	0.22	ENSG00000266452	.	202169	0.03
chr1_161016731_161016999	0.22	USF1	upstream transcription factor 1	1098	0.3
chr4_38673361_38673512	0.22	RP11-617D20.1		6932	0.18
chr16_4422377_4422562	0.22	VASN	vasorin	620	0.61
chr5_114937358_114937534	0.22	AC010226.4		308	0.74
chr14_69239916_69240125	0.22	ZFP36L1	ZFP36 ring finger protein-like 1	17940	0.2
chr2_10815541_10815692	0.22	NOL10	nucleolar protein 10	3800	0.22
chr18_68339531_68339691	0.21	GTSCR1	Gilles de la Tourette syndrome chromosome region, candidate 1	21631	0.28
chr5_94378324_94378475	0.21	MCTP1	multiple C2 domains, transmembrane 1	25208	0.24
chrX_40036930_40037081	0.21	BCOR	BCL6 corepressor	423	0.91
chr3_43343509_43343660	0.21	ENSG00000241939	.	12859	0.17
chr1_89587383_89587534	0.21	GBP2	guanylate binding protein 2, interferon-inducible	4339	0.22
chr1_226871894_226872507	0.21	ITPKB-IT1	ITPKB intronic transcript 1 (non-protein coding)	9432	0.21
chr6_47321141_47321456	0.21	TNFRSF21	tumor necrosis factor receptor superfamily, member 21	43657	0.18
chr15_76196509_76196759	0.21	FBXO22	F-box protein 22	168	0.94

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of PBX3

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	0.5	GO:0035405	histone-threonine phosphorylation(GO:0035405)
0.1	0.5	GO:0031061	negative regulation of histone methylation(GO:0031061)
0.1	0.3	GO:0032237	activation of store-operated calcium channel activity(GO:0032237) regulation of store-operated calcium channel activity(GO:1901339) positive regulation of store-operated calcium channel activity(GO:1901341)
0.1	0.2	GO:0060340	positive regulation of type I interferon-mediated signaling pathway(GO:0060340)
0.1	0.2	GO:0010572	positive regulation of platelet activation(GO:0010572)
0.1	0.3	GO:0002282	microglial cell activation involved in immune response(GO:0002282)
0.1	0.2	GO:0001672	regulation of chromatin assembly or disassembly(GO:0001672)
0.1	0.2	GO:0034626	fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.1	0.2	GO:0014041	regulation of neuron maturation(GO:0014041) regulation of cell maturation(GO:1903429)
0.1	0.2	GO:0030854	positive regulation of granulocyte differentiation(GO:0030854)
0.1	0.2	GO:0046137	negative regulation of calcidiol 1-monooxygenase activity(GO:0010956) negative regulation of vitamin D biosynthetic process(GO:0010957) negative regulation of vitamin metabolic process(GO:0046137)
0.1	0.2	GO:0010459	negative regulation of heart rate(GO:0010459)
0.1	0.2	GO:0021798	forebrain dorsal/ventral pattern formation(GO:0021798)
0.1	0.4	GO:0051001	negative regulation of nitric-oxide synthase activity(GO:0051001)
0.1	0.2	GO:0051665	membrane raft localization(GO:0051665)
0.1	0.2	GO:0021898	commitment of multipotent stem cells to neuronal lineage in forebrain(GO:0021898)
0.1	0.2	GO:1901522	positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus(GO:1901522)
0.0	0.1	GO:0032543	mitochondrial translation(GO:0032543)
0.0	0.2	GO:0007023	post-chaperonin tubulin folding pathway(GO:0007023)
0.0	0.4	GO:0007172	signal complex assembly(GO:0007172)
0.0	0.1	GO:0030223	neutrophil differentiation(GO:0030223)
0.0	0.2	GO:0018101	protein citrullination(GO:0018101)
0.0	0.1	GO:0045722	positive regulation of gluconeogenesis(GO:0045722)
0.0	0.1	GO:0002691	regulation of cellular extravasation(GO:0002691) positive regulation of cellular extravasation(GO:0002693)
0.0	0.2	GO:0045349	interferon-alpha biosynthetic process(GO:0045349) regulation of interferon-alpha biosynthetic process(GO:0045354)
0.0	0.1	GO:0032632	interleukin-3 production(GO:0032632)
0.0	0.1	GO:0006384	transcription initiation from RNA polymerase III promoter(GO:0006384)
0.0	0.0	GO:0033080	immature T cell proliferation in thymus(GO:0033080)
0.0	0.5	GO:0031648	protein destabilization(GO:0031648)
0.0	0.0	GO:0045586	regulation of gamma-delta T cell differentiation(GO:0045586) positive regulation of gamma-delta T cell differentiation(GO:0045588)
0.0	0.0	GO:0002523	leukocyte migration involved in inflammatory response(GO:0002523)
0.0	0.1	GO:0033152	immunoglobulin V(D)J recombination(GO:0033152)
0.0	0.0	GO:0042492	gamma-delta T cell differentiation(GO:0042492)
0.0	0.1	GO:0071392	cellular response to estradiol stimulus(GO:0071392)
0.0	0.1	GO:0006003	fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.0	0.0	GO:0002888	positive regulation of myeloid leukocyte mediated immunity(GO:0002888)
0.0	0.1	GO:0034139	regulation of toll-like receptor 3 signaling pathway(GO:0034139)
0.0	0.1	GO:0006167	AMP biosynthetic process(GO:0006167)
0.0	0.1	GO:0043320	natural killer cell activation involved in immune response(GO:0002323) natural killer cell degranulation(GO:0043320)
0.0	0.2	GO:0006685	sphingomyelin catabolic process(GO:0006685)
0.0	0.1	GO:0010882	regulation of cardiac muscle contraction by calcium ion signaling(GO:0010882)
0.0	0.2	GO:0030889	negative regulation of B cell proliferation(GO:0030889)
0.0	0.3	GO:0034260	negative regulation of GTPase activity(GO:0034260)
0.0	0.1	GO:0032525	somite rostral/caudal axis specification(GO:0032525)
0.0	0.1	GO:0046471	phosphatidylglycerol biosynthetic process(GO:0006655) cardiolipin metabolic process(GO:0032048) cardiolipin biosynthetic process(GO:0032049) phosphatidylglycerol metabolic process(GO:0046471)
0.0	0.1	GO:0072385	minus-end-directed organelle transport along microtubule(GO:0072385)
0.0	0.1	GO:0071481	cellular response to X-ray(GO:0071481)
0.0	0.1	GO:0001845	phagolysosome assembly(GO:0001845) phagosome maturation(GO:0090382)
0.0	0.1	GO:0048643	positive regulation of skeletal muscle tissue development(GO:0048643)
0.0	0.2	GO:0048268	clathrin coat assembly(GO:0048268)
0.0	0.1	GO:0010614	negative regulation of cardiac muscle hypertrophy(GO:0010614)
0.0	0.6	GO:0045576	mast cell activation(GO:0045576)
0.0	0.1	GO:0033147	negative regulation of intracellular estrogen receptor signaling pathway(GO:0033147)
0.0	0.1	GO:0071436	sodium ion export(GO:0071436)
0.0	0.1	GO:0032661	interleukin-18 production(GO:0032621) regulation of interleukin-18 production(GO:0032661)
0.0	0.1	GO:2000095	regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000095)
0.0	0.1	GO:0051569	regulation of histone H3-K4 methylation(GO:0051569)
0.0	0.1	GO:0032506	cytokinetic process(GO:0032506)
0.0	0.1	GO:0015917	aminophospholipid transport(GO:0015917)
0.0	0.1	GO:0060586	multicellular organismal iron ion homeostasis(GO:0060586)
0.0	0.1	GO:0002513	tolerance induction to self antigen(GO:0002513)
0.0	0.1	GO:0008354	germ cell migration(GO:0008354)
0.0	0.1	GO:0019441	tryptophan catabolic process to kynurenine(GO:0019441)
0.0	0.1	GO:0032509	endosome transport via multivesicular body sorting pathway(GO:0032509)
0.0	0.1	GO:0060397	JAK-STAT cascade involved in growth hormone signaling pathway(GO:0060397)
0.0	0.1	GO:0034616	response to laminar fluid shear stress(GO:0034616)
0.0	0.0	GO:0032613	interleukin-10 production(GO:0032613)
0.0	0.1	GO:0009313	oligosaccharide catabolic process(GO:0009313)
0.0	0.1	GO:0045542	positive regulation of cholesterol biosynthetic process(GO:0045542)
0.0	0.1	GO:0002862	negative regulation of inflammatory response to antigenic stimulus(GO:0002862)
0.0	0.1	GO:0048096	chromatin-mediated maintenance of transcription(GO:0048096)
0.0	0.2	GO:0050957	equilibrioception(GO:0050957)
0.0	0.0	GO:0090085	regulation of protein deubiquitination(GO:0090085)
0.0	0.1	GO:0050857	positive regulation of antigen receptor-mediated signaling pathway(GO:0050857)
0.0	0.1	GO:0070837	dehydroascorbic acid transport(GO:0070837)
0.0	0.1	GO:0002726	positive regulation of T cell cytokine production(GO:0002726)
0.0	0.3	GO:0032008	positive regulation of TOR signaling(GO:0032008)
0.0	0.1	GO:0001562	response to protozoan(GO:0001562)
0.0	0.1	GO:0051491	positive regulation of filopodium assembly(GO:0051491)
0.0	0.0	GO:0061154	endothelial tube morphogenesis(GO:0061154)
0.0	0.1	GO:0048563	post-embryonic organ morphogenesis(GO:0048563)
0.0	0.1	GO:0019987	obsolete negative regulation of anti-apoptosis(GO:0019987)
0.0	0.3	GO:0006957	complement activation, alternative pathway(GO:0006957)
0.0	0.0	GO:0061030	epithelial cell differentiation involved in mammary gland alveolus development(GO:0061030)
0.0	0.0	GO:0006089	lactate metabolic process(GO:0006089)
0.0	0.1	GO:0015801	aromatic amino acid transport(GO:0015801)
0.0	0.0	GO:0002495	antigen processing and presentation of peptide antigen via MHC class II(GO:0002495)
0.0	0.0	GO:0048537	mucosal-associated lymphoid tissue development(GO:0048537)
0.0	0.1	GO:0032486	Rap protein signal transduction(GO:0032486)
0.0	0.1	GO:0008049	male courtship behavior(GO:0008049)
0.0	0.1	GO:0008631	intrinsic apoptotic signaling pathway in response to oxidative stress(GO:0008631) cell death in response to oxidative stress(GO:0036473)
0.0	0.1	GO:0043951	negative regulation of cAMP-mediated signaling(GO:0043951)
0.0	0.1	GO:0060219	camera-type eye photoreceptor cell differentiation(GO:0060219)
0.0	0.1	GO:0050686	negative regulation of mRNA processing(GO:0050686) negative regulation of mRNA metabolic process(GO:1903312)
0.0	0.0	GO:0042091	interleukin-10 biosynthetic process(GO:0042091) regulation of interleukin-10 biosynthetic process(GO:0045074)
0.0	0.1	GO:0019859	pyrimidine nucleobase catabolic process(GO:0006208) thymine catabolic process(GO:0006210) thymine metabolic process(GO:0019859)
0.0	0.4	GO:0045646	regulation of erythrocyte differentiation(GO:0045646)
0.0	0.0	GO:0001866	NK T cell proliferation(GO:0001866)
0.0	0.2	GO:0007158	neuron cell-cell adhesion(GO:0007158)
0.0	0.0	GO:0021778	spinal cord oligodendrocyte cell differentiation(GO:0021529) spinal cord oligodendrocyte cell fate specification(GO:0021530) oligodendrocyte cell fate specification(GO:0021778) glial cell fate specification(GO:0021780)
0.0	0.0	GO:0002335	mature B cell differentiation(GO:0002335)
0.0	0.1	GO:0048712	negative regulation of astrocyte differentiation(GO:0048712)
0.0	0.0	GO:0010310	regulation of hydrogen peroxide metabolic process(GO:0010310)
0.0	0.1	GO:0009221	pyrimidine deoxyribonucleotide biosynthetic process(GO:0009221)
0.0	0.1	GO:2000758	positive regulation of histone acetylation(GO:0035066) positive regulation of protein acetylation(GO:1901985) positive regulation of peptidyl-lysine acetylation(GO:2000758)
0.0	0.0	GO:0072201	negative regulation of mesenchymal cell proliferation(GO:0072201)
0.0	0.3	GO:0032012	regulation of ARF protein signal transduction(GO:0032012)
0.0	0.0	GO:0072600	protein targeting to Golgi(GO:0000042) establishment of protein localization to Golgi(GO:0072600)
0.0	0.1	GO:0007095	mitotic G2 DNA damage checkpoint(GO:0007095)
0.0	0.0	GO:0043374	CD8-positive, alpha-beta T cell activation(GO:0036037) CD8-positive, alpha-beta T cell differentiation(GO:0043374)
0.0	0.1	GO:0008588	release of cytoplasmic sequestered NF-kappaB(GO:0008588)
0.0	0.1	GO:0060528	secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development(GO:0060528)
0.0	0.0	GO:0010980	regulation of vitamin D 24-hydroxylase activity(GO:0010979) positive regulation of vitamin D 24-hydroxylase activity(GO:0010980)
0.0	0.1	GO:0022614	membrane to membrane docking(GO:0022614)
0.0	0.1	GO:0045746	negative regulation of Notch signaling pathway(GO:0045746)
0.0	0.1	GO:0060164	regulation of timing of neuron differentiation(GO:0060164)
0.0	0.1	GO:0072077	mesenchymal to epithelial transition involved in metanephros morphogenesis(GO:0003337) renal vesicle morphogenesis(GO:0072077) metanephric renal vesicle morphogenesis(GO:0072283)
0.0	0.1	GO:0008298	intracellular mRNA localization(GO:0008298)
0.0	0.0	GO:0010940	positive regulation of necrotic cell death(GO:0010940)
0.0	0.3	GO:0043124	negative regulation of I-kappaB kinase/NF-kappaB signaling(GO:0043124)
0.0	0.1	GO:0002507	tolerance induction(GO:0002507)
0.0	0.1	GO:0071636	positive regulation of transforming growth factor beta production(GO:0071636)
0.0	0.0	GO:0000301	retrograde transport, vesicle recycling within Golgi(GO:0000301)
0.0	0.1	GO:0006772	thiamine metabolic process(GO:0006772)
0.0	0.1	GO:0061756	leukocyte tethering or rolling(GO:0050901) leukocyte adhesion to vascular endothelial cell(GO:0061756)
0.0	0.1	GO:0006610	ribosomal protein import into nucleus(GO:0006610)
0.0	0.0	GO:0002724	regulation of T cell cytokine production(GO:0002724)
0.0	0.1	GO:0010508	positive regulation of autophagy(GO:0010508)
0.0	0.3	GO:0045730	respiratory burst(GO:0045730)
0.0	0.0	GO:0015809	arginine transport(GO:0015809)
0.0	0.3	GO:0006607	NLS-bearing protein import into nucleus(GO:0006607)
0.0	0.1	GO:0032836	glomerular basement membrane development(GO:0032836)
0.0	0.1	GO:0032328	alanine transport(GO:0032328)
0.0	0.1	GO:0009972	cytidine catabolic process(GO:0006216) cytidine deamination(GO:0009972) cytidine metabolic process(GO:0046087)
0.0	0.1	GO:0032000	positive regulation of fatty acid beta-oxidation(GO:0032000)
0.0	0.1	GO:0006538	glutamate catabolic process(GO:0006538)
0.0	0.1	GO:0042535	positive regulation of tumor necrosis factor biosynthetic process(GO:0042535)
0.0	0.1	GO:0046033	AMP metabolic process(GO:0046033)
0.0	0.0	GO:0034122	negative regulation of toll-like receptor signaling pathway(GO:0034122)
0.0	0.1	GO:0042989	sequestering of actin monomers(GO:0042989)
0.0	0.0	GO:0006287	base-excision repair, gap-filling(GO:0006287)
0.0	0.1	GO:0031000	response to caffeine(GO:0031000)
0.0	0.0	GO:0071698	olfactory placode formation(GO:0030910) olfactory placode development(GO:0071698) olfactory placode morphogenesis(GO:0071699)
0.0	0.0	GO:0001779	natural killer cell differentiation(GO:0001779)
0.0	0.1	GO:0032733	positive regulation of interleukin-10 production(GO:0032733)
0.0	0.1	GO:0045351	type I interferon biosynthetic process(GO:0045351)
0.0	0.1	GO:0002430	complement receptor mediated signaling pathway(GO:0002430)
0.0	0.1	GO:0022417	protein maturation by protein folding(GO:0022417)
0.0	0.1	GO:0043551	regulation of phosphatidylinositol 3-kinase activity(GO:0043551) positive regulation of phosphatidylinositol 3-kinase activity(GO:0043552)
0.0	0.1	GO:0060236	regulation of mitotic spindle organization(GO:0060236)
0.0	0.0	GO:0002903	negative regulation of B cell apoptotic process(GO:0002903)
0.0	0.0	GO:0019228	neuronal action potential(GO:0019228)
0.0	0.0	GO:0006922	obsolete cleavage of lamin involved in execution phase of apoptosis(GO:0006922)
0.0	0.1	GO:0048625	myoblast fate commitment(GO:0048625)
0.0	0.1	GO:0051974	negative regulation of telomerase activity(GO:0051974)
0.0	0.2	GO:0051923	sulfation(GO:0051923)
0.0	0.1	GO:0006032	chitin metabolic process(GO:0006030) chitin catabolic process(GO:0006032)
0.0	0.1	GO:0090322	regulation of superoxide metabolic process(GO:0090322)
0.0	0.1	GO:0070935	3'-UTR-mediated mRNA stabilization(GO:0070935)
0.0	0.1	GO:0051788	response to misfolded protein(GO:0051788)
0.0	0.1	GO:0048172	regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.0	0.0	GO:0060439	trachea morphogenesis(GO:0060439)
0.0	0.1	GO:0045906	negative regulation of vasoconstriction(GO:0045906)
0.0	0.2	GO:0015693	magnesium ion transport(GO:0015693)
0.0	0.1	GO:0045048	protein insertion into ER membrane(GO:0045048) tail-anchored membrane protein insertion into ER membrane(GO:0071816)
0.0	0.0	GO:0070574	cadmium ion transport(GO:0015691) cadmium ion transmembrane transport(GO:0070574)
0.0	0.1	GO:0042663	endodermal cell fate specification(GO:0001714) regulation of endodermal cell fate specification(GO:0042663) regulation of endodermal cell differentiation(GO:1903224)
0.0	0.4	GO:1901800	positive regulation of proteasomal ubiquitin-dependent protein catabolic process(GO:0032436) positive regulation of proteasomal protein catabolic process(GO:1901800)
0.0	0.0	GO:0032905	transforming growth factor beta1 production(GO:0032905) regulation of transforming growth factor beta1 production(GO:0032908)
0.0	0.1	GO:0090400	stress-induced premature senescence(GO:0090400)
0.0	0.0	GO:0071360	cellular response to exogenous dsRNA(GO:0071360)
0.0	0.2	GO:0050832	defense response to fungus(GO:0050832)
0.0	0.0	GO:0032790	ribosome disassembly(GO:0032790)
0.0	0.0	GO:0072498	embryonic skeletal joint morphogenesis(GO:0060272) embryonic skeletal joint development(GO:0072498)
0.0	0.2	GO:0006044	N-acetylglucosamine metabolic process(GO:0006044)
0.0	0.1	GO:0032528	microvillus assembly(GO:0030033) microvillus organization(GO:0032528)
0.0	0.1	GO:0048242	epinephrine transport(GO:0048241) epinephrine secretion(GO:0048242)
0.0	0.1	GO:0002052	positive regulation of neuroblast proliferation(GO:0002052)
0.0	0.0	GO:0006154	adenosine catabolic process(GO:0006154)
0.0	0.0	GO:0051097	negative regulation of helicase activity(GO:0051097)
0.0	0.1	GO:0006265	DNA topological change(GO:0006265)
0.0	0.0	GO:0045123	cellular extravasation(GO:0045123)
0.0	0.1	GO:0032814	regulation of natural killer cell activation(GO:0032814)
0.0	0.1	GO:0070498	interleukin-1-mediated signaling pathway(GO:0070498)
0.0	0.1	GO:0016572	histone phosphorylation(GO:0016572)
0.0	0.0	GO:0032898	neurotrophin production(GO:0032898)
0.0	0.1	GO:0008625	extrinsic apoptotic signaling pathway via death domain receptors(GO:0008625) extrinsic apoptotic signaling pathway(GO:0097191)
0.0	0.0	GO:0051489	regulation of filopodium assembly(GO:0051489)
0.0	0.0	GO:0006924	activation-induced cell death of T cells(GO:0006924)
0.0	0.1	GO:0009129	pyrimidine nucleoside monophosphate metabolic process(GO:0009129)
0.0	0.0	GO:0033148	positive regulation of intracellular estrogen receptor signaling pathway(GO:0033148)
0.0	0.0	GO:0001574	ganglioside biosynthetic process(GO:0001574)
0.0	0.0	GO:0042362	fat-soluble vitamin biosynthetic process(GO:0042362)
0.0	0.1	GO:0032148	activation of protein kinase B activity(GO:0032148)
0.0	0.0	GO:0002085	inhibition of neuroepithelial cell differentiation(GO:0002085)
0.0	0.1	GO:0060123	regulation of growth hormone secretion(GO:0060123)
0.0	0.0	GO:0030186	melatonin metabolic process(GO:0030186) melatonin biosynthetic process(GO:0030187)
0.0	0.1	GO:0000479	endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000447) maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000462) cleavage involved in rRNA processing(GO:0000469) endonucleolytic cleavage involved in rRNA processing(GO:0000478) endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000479) RNA phosphodiester bond hydrolysis, endonucleolytic(GO:0090502)
0.0	0.1	GO:0006999	nuclear pore organization(GO:0006999)
0.0	0.1	GO:2000258	negative regulation of complement activation(GO:0045916) negative regulation of protein activation cascade(GO:2000258)
0.0	0.0	GO:0021781	glial cell fate commitment(GO:0021781)
0.0	0.0	GO:0010761	fibroblast migration(GO:0010761)
0.0	0.0	GO:0051103	DNA ligation involved in DNA repair(GO:0051103)
0.0	0.1	GO:0000185	activation of MAPKKK activity(GO:0000185)
0.0	0.0	GO:0043653	mitochondrial fragmentation involved in apoptotic process(GO:0043653)
0.0	0.1	GO:0046884	follicle-stimulating hormone secretion(GO:0046884)
0.0	0.3	GO:0007257	activation of JUN kinase activity(GO:0007257)
0.0	0.0	GO:0045071	negative regulation of viral genome replication(GO:0045071)
0.0	0.1	GO:0051085	chaperone mediated protein folding requiring cofactor(GO:0051085)
0.0	0.0	GO:0051290	protein heterotetramerization(GO:0051290)
0.0	0.0	GO:0048304	positive regulation of isotype switching to IgG isotypes(GO:0048304)
0.0	0.1	GO:0001782	B cell homeostasis(GO:0001782)
0.0	0.0	GO:0000733	DNA strand renaturation(GO:0000733)
0.0	0.1	GO:0043550	regulation of lipid kinase activity(GO:0043550)
0.0	0.1	GO:0040015	negative regulation of multicellular organism growth(GO:0040015)
0.0	0.0	GO:0043931	ossification involved in bone maturation(GO:0043931)
0.0	0.1	GO:0060330	regulation of response to interferon-gamma(GO:0060330) regulation of interferon-gamma-mediated signaling pathway(GO:0060334)
0.0	0.0	GO:0061384	heart trabecula formation(GO:0060347) heart trabecula morphogenesis(GO:0061384)
0.0	0.2	GO:0015893	drug transport(GO:0015893)
0.0	0.1	GO:0006561	proline biosynthetic process(GO:0006561)
0.0	0.1	GO:0007216	G-protein coupled glutamate receptor signaling pathway(GO:0007216)
0.0	0.0	GO:0045603	positive regulation of endothelial cell differentiation(GO:0045603)
0.0	0.0	GO:0019532	oxalate transport(GO:0019532)
0.0	0.0	GO:0051770	positive regulation of nitric-oxide synthase biosynthetic process(GO:0051770)
0.0	0.0	GO:0047484	regulation of response to osmotic stress(GO:0047484)
0.0	0.1	GO:0010890	positive regulation of sequestering of triglyceride(GO:0010890)
0.0	0.1	GO:0000183	chromatin silencing at rDNA(GO:0000183)
0.0	0.1	GO:0019388	galactose catabolic process(GO:0019388)
0.0	0.1	GO:0006422	aspartyl-tRNA aminoacylation(GO:0006422)
0.0	0.0	GO:0045084	positive regulation of interleukin-12 biosynthetic process(GO:0045084)
0.0	0.0	GO:0072205	metanephric collecting duct development(GO:0072205)
0.0	0.5	GO:0006968	cellular defense response(GO:0006968)
0.0	0.0	GO:0019255	glucose 1-phosphate metabolic process(GO:0019255)
0.0	0.2	GO:0050850	positive regulation of calcium-mediated signaling(GO:0050850)
0.0	0.1	GO:0042348	regulation of NF-kappaB import into nucleus(GO:0042345) NF-kappaB import into nucleus(GO:0042348)
0.0	0.1	GO:0015886	heme transport(GO:0015886)
0.0	0.0	GO:0006667	sphinganine metabolic process(GO:0006667)
0.0	0.0	GO:0003402	planar cell polarity pathway involved in axis elongation(GO:0003402)
0.0	0.0	GO:0042726	flavin-containing compound metabolic process(GO:0042726)
0.0	0.0	GO:0043368	positive T cell selection(GO:0043368)
0.0	0.1	GO:0016255	attachment of GPI anchor to protein(GO:0016255)
0.0	0.1	GO:0050667	homocysteine metabolic process(GO:0050667)
0.0	0.0	GO:0001821	histamine secretion(GO:0001821)
0.0	0.1	GO:0015074	DNA integration(GO:0015074)
0.0	0.0	GO:0042104	positive regulation of activated T cell proliferation(GO:0042104)
0.0	0.0	GO:0045040	outer mitochondrial membrane organization(GO:0007008) protein import into mitochondrial outer membrane(GO:0045040)
0.0	0.2	GO:0006297	nucleotide-excision repair, DNA gap filling(GO:0006297)
0.0	0.2	GO:0034199	activation of protein kinase A activity(GO:0034199)
0.0	0.0	GO:0003351	epithelial cilium movement(GO:0003351) epithelial cilium movement involved in determination of left/right asymmetry(GO:0060287)
0.0	0.1	GO:0031053	primary miRNA processing(GO:0031053)
0.0	0.0	GO:0019372	lipoxygenase pathway(GO:0019372)
0.0	0.2	GO:1901661	quinone metabolic process(GO:1901661)
0.0	0.1	GO:0016973	poly(A)+ mRNA export from nucleus(GO:0016973)
0.0	0.0	GO:0040016	embryonic cleavage(GO:0040016)
0.0	0.1	GO:0061088	regulation of sequestering of zinc ion(GO:0061088)
0.0	0.0	GO:0001820	serotonin secretion(GO:0001820)
0.0	0.0	GO:0000470	maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000463) maturation of LSU-rRNA(GO:0000470)
0.0	0.0	GO:0010626	regulation of Schwann cell proliferation(GO:0010624) negative regulation of Schwann cell proliferation(GO:0010626)
0.0	0.1	GO:0006102	isocitrate metabolic process(GO:0006102)
0.0	0.7	GO:0071357	type I interferon signaling pathway(GO:0060337) cellular response to type I interferon(GO:0071357)
0.0	0.0	GO:0060684	epithelial-mesenchymal cell signaling(GO:0060684)
0.0	0.0	GO:0060913	cardiac cell fate determination(GO:0060913)
0.0	0.0	GO:0001831	trophectodermal cellular morphogenesis(GO:0001831)
0.0	0.1	GO:0005513	detection of calcium ion(GO:0005513)
0.0	0.0	GO:0046827	positive regulation of protein export from nucleus(GO:0046827)
0.0	0.1	GO:0015937	coenzyme A biosynthetic process(GO:0015937)
0.0	0.0	GO:0007638	mechanosensory behavior(GO:0007638)
0.0	0.0	GO:0072531	pyrimidine-containing compound transmembrane transport(GO:0072531)
0.0	0.1	GO:0032205	negative regulation of telomere maintenance(GO:0032205)
0.0	0.0	GO:1901978	positive regulation of spindle checkpoint(GO:0090232) regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090266) positive regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090267) positive regulation of cell cycle checkpoint(GO:1901978) regulation of mitotic spindle checkpoint(GO:1903504)
0.0	0.0	GO:0060999	positive regulation of dendritic spine development(GO:0060999)
0.0	0.1	GO:0042572	retinol metabolic process(GO:0042572)
0.0	0.1	GO:0045725	positive regulation of glycogen biosynthetic process(GO:0045725)
0.0	0.1	GO:0006388	RNA splicing, via endonucleolytic cleavage and ligation(GO:0000394) tRNA splicing, via endonucleolytic cleavage and ligation(GO:0006388)
0.0	0.0	GO:0033522	histone H2A ubiquitination(GO:0033522)
0.0	0.0	GO:0071364	cellular response to epidermal growth factor stimulus(GO:0071364)
0.0	0.0	GO:0003283	atrial septum development(GO:0003283) atrial septum morphogenesis(GO:0060413)
0.0	0.1	GO:0032092	positive regulation of protein binding(GO:0032092)
0.0	0.0	GO:0045162	clustering of voltage-gated sodium channels(GO:0045162)
0.0	0.0	GO:0014805	smooth muscle adaptation(GO:0014805)
0.0	0.1	GO:0006465	signal peptide processing(GO:0006465)
0.0	0.0	GO:0000089	mitotic metaphase(GO:0000089)
0.0	0.0	GO:0002475	antigen processing and presentation via MHC class Ib(GO:0002475)
0.0	0.0	GO:0090009	primitive streak formation(GO:0090009)
0.0	0.1	GO:0006684	sphingomyelin metabolic process(GO:0006684)
0.0	0.0	GO:0031440	regulation of mRNA 3'-end processing(GO:0031440) positive regulation of mRNA 3'-end processing(GO:0031442) positive regulation of mRNA processing(GO:0050685) positive regulation of mRNA metabolic process(GO:1903313)
0.0	0.1	GO:0009249	protein lipoylation(GO:0009249)
0.0	0.0	GO:0070233	negative regulation of T cell apoptotic process(GO:0070233)
0.0	0.0	GO:0003032	detection of oxygen(GO:0003032)
0.0	0.1	GO:0006516	glycoprotein catabolic process(GO:0006516)
0.0	0.0	GO:0072526	pyridine-containing compound catabolic process(GO:0072526)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.6	GO:0043020	NADPH oxidase complex(GO:0043020)
0.1	0.2	GO:0071986	Ragulator complex(GO:0071986)
0.1	0.3	GO:0031088	platelet dense granule membrane(GO:0031088)
0.0	0.2	GO:0000137	Golgi cis cisterna(GO:0000137)
0.0	0.3	GO:0005652	nuclear lamina(GO:0005652)
0.0	0.2	GO:0043218	compact myelin(GO:0043218)
0.0	0.2	GO:0034045	pre-autophagosomal structure membrane(GO:0034045)
0.0	0.4	GO:0035098	ESC/E(Z) complex(GO:0035098)
0.0	0.3	GO:0005577	fibrinogen complex(GO:0005577)
0.0	0.1	GO:0005826	actomyosin contractile ring(GO:0005826)
0.0	0.1	GO:0032809	neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.0	0.1	GO:0031313	extrinsic component of vacuolar membrane(GO:0000306) extrinsic component of endosome membrane(GO:0031313)
0.0	0.1	GO:0045323	interleukin-1 receptor complex(GO:0045323)
0.0	0.0	GO:0070044	synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044)
0.0	0.1	GO:0031205	endoplasmic reticulum Sec complex(GO:0031205)
0.0	0.1	GO:0031235	intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.0	0.1	GO:0000942	condensed nuclear chromosome outer kinetochore(GO:0000942)
0.0	0.1	GO:0030119	AP-type membrane coat adaptor complex(GO:0030119)
0.0	0.2	GO:0001891	phagocytic cup(GO:0001891)
0.0	0.1	GO:0032009	early phagosome(GO:0032009)
0.0	0.3	GO:0031519	PcG protein complex(GO:0031519)
0.0	0.2	GO:0048786	presynaptic active zone(GO:0048786)
0.0	0.0	GO:0000778	condensed nuclear chromosome kinetochore(GO:0000778)
0.0	0.0	GO:0001950	obsolete plasma membrane enriched fraction(GO:0001950)
0.0	0.0	GO:0031312	extrinsic component of organelle membrane(GO:0031312)
0.0	0.1	GO:0031229	integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229) nuclear membrane part(GO:0044453)
0.0	0.0	GO:0031932	TORC2 complex(GO:0031932)
0.0	0.0	GO:0033270	paranode region of axon(GO:0033270)
0.0	0.1	GO:0042405	nuclear inclusion body(GO:0042405)
0.0	0.0	GO:0060199	clathrin-sculpted glutamate transport vesicle(GO:0060199) clathrin-sculpted glutamate transport vesicle membrane(GO:0060203)
0.0	0.1	GO:0045179	apical cortex(GO:0045179)
0.0	0.2	GO:0043209	myelin sheath(GO:0043209)
0.0	0.2	GO:0005942	phosphatidylinositol 3-kinase complex(GO:0005942)
0.0	0.1	GO:0005947	mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947)
0.0	0.1	GO:0019773	proteasome core complex, alpha-subunit complex(GO:0019773)
0.0	0.2	GO:0008250	oligosaccharyltransferase complex(GO:0008250)
0.0	0.1	GO:0005885	Arp2/3 protein complex(GO:0005885)
0.0	0.1	GO:0072379	BAT3 complex(GO:0071818) ER membrane insertion complex(GO:0072379)
0.0	0.1	GO:0030895	apolipoprotein B mRNA editing enzyme complex(GO:0030895)
0.0	0.1	GO:0042582	primary lysosome(GO:0005766) azurophil granule(GO:0042582)
0.0	0.1	GO:0070688	MLL5-L complex(GO:0070688)
0.0	0.1	GO:0090576	RNA polymerase III transcription factor complex(GO:0090576)
0.0	0.1	GO:0031083	BLOC complex(GO:0031082) BLOC-1 complex(GO:0031083)
0.0	0.1	GO:0014701	junctional sarcoplasmic reticulum membrane(GO:0014701)
0.0	0.0	GO:0031931	TORC1 complex(GO:0031931)
0.0	0.1	GO:0034451	centriolar satellite(GO:0034451)
0.0	0.0	GO:0032045	guanyl-nucleotide exchange factor complex(GO:0032045)
0.0	0.1	GO:0008290	F-actin capping protein complex(GO:0008290)
0.0	0.0	GO:0070022	transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.0	0.1	GO:0033553	rDNA heterochromatin(GO:0033553)
0.0	0.2	GO:0016514	SWI/SNF complex(GO:0016514)
0.0	0.0	GO:0000214	tRNA-intron endonuclease complex(GO:0000214)
0.0	0.2	GO:0043195	terminal bouton(GO:0043195)
0.0	0.0	GO:0033150	cytoskeletal calyx(GO:0033150)
0.0	0.2	GO:0042101	T cell receptor complex(GO:0042101)
0.0	0.1	GO:0005827	polar microtubule(GO:0005827)
0.0	0.0	GO:0044462	external encapsulating structure part(GO:0044462)
0.0	0.2	GO:0005844	polysome(GO:0005844)
0.0	0.1	GO:0030121	AP-1 adaptor complex(GO:0030121)
0.0	0.0	GO:0072487	MSL complex(GO:0072487)
0.0	0.0	GO:0032593	insulin-responsive compartment(GO:0032593)
0.0	0.1	GO:0061202	clathrin-sculpted gamma-aminobutyric acid transport vesicle(GO:0061200) clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane(GO:0061202)
0.0	0.0	GO:0000124	SAGA complex(GO:0000124)
0.0	0.1	GO:0001772	immunological synapse(GO:0001772)
0.0	0.1	GO:0031254	uropod(GO:0001931) cell trailing edge(GO:0031254)
0.0	0.1	GO:0035631	CD40 receptor complex(GO:0035631)
0.0	0.0	GO:0030688	preribosome, small subunit precursor(GO:0030688)
0.0	0.4	GO:0030118	clathrin coat(GO:0030118)
0.0	0.1	GO:0032156	septin complex(GO:0031105) septin cytoskeleton(GO:0032156)
0.0	0.0	GO:0005677	chromatin silencing complex(GO:0005677)
0.0	0.3	GO:0005626	obsolete insoluble fraction(GO:0005626)
0.0	0.0	GO:0042827	platelet dense granule(GO:0042827)
0.0	0.0	GO:0070545	PeBoW complex(GO:0070545)
0.0	0.1	GO:0031080	nuclear pore outer ring(GO:0031080)
0.0	0.0	GO:0046696	lipopolysaccharide receptor complex(GO:0046696)
0.0	0.1	GO:0016461	unconventional myosin complex(GO:0016461)
0.0	0.0	GO:0001740	Barr body(GO:0001740)
0.0	0.0	GO:0044224	juxtaparanode region of axon(GO:0044224)
0.0	1.0	GO:0019717	obsolete synaptosome(GO:0019717)
0.0	0.1	GO:0000796	condensin complex(GO:0000796)
0.0	0.1	GO:0005663	DNA replication factor C complex(GO:0005663)
0.0	0.1	GO:0046581	intercellular canaliculus(GO:0046581)
0.0	0.0	GO:0000800	lateral element(GO:0000800)
0.0	0.1	GO:0031010	ISWI-type complex(GO:0031010)
0.0	0.0	GO:0005686	U2 snRNP(GO:0005686)
0.0	0.2	GO:0032420	stereocilium(GO:0032420)
0.0	0.1	GO:0034362	low-density lipoprotein particle(GO:0034362)
0.0	0.0	GO:0014731	spectrin-associated cytoskeleton(GO:0014731)
0.0	0.1	GO:0010494	cytoplasmic stress granule(GO:0010494)
0.0	0.2	GO:0005892	acetylcholine-gated channel complex(GO:0005892)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	0.5	GO:0035184	histone threonine kinase activity(GO:0035184)
0.1	0.5	GO:0030676	Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.1	0.2	GO:0005152	interleukin-1 receptor antagonist activity(GO:0005152)
0.1	0.2	GO:0047894	flavonol 3-sulfotransferase activity(GO:0047894)
0.1	0.2	GO:0019911	structural constituent of myelin sheath(GO:0019911)
0.1	0.2	GO:0046935	1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.1	0.6	GO:0016493	C-C chemokine receptor activity(GO:0016493)
0.1	0.2	GO:0008420	CTD phosphatase activity(GO:0008420)
0.1	0.2	GO:0033691	sialic acid binding(GO:0033691)
0.1	0.2	GO:0004949	cannabinoid receptor activity(GO:0004949)
0.1	0.2	GO:0047623	AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.0	0.2	GO:0004668	protein-arginine deiminase activity(GO:0004668)
0.0	0.1	GO:0004351	glutamate decarboxylase activity(GO:0004351)
0.0	0.1	GO:0004911	interleukin-2 receptor activity(GO:0004911)
0.0	0.1	GO:0016842	amidine-lyase activity(GO:0016842)
0.0	0.1	GO:0016748	succinyltransferase activity(GO:0016748)
0.0	0.1	GO:0003873	6-phosphofructo-2-kinase activity(GO:0003873)
0.0	0.1	GO:0061505	DNA topoisomerase type II (ATP-hydrolyzing) activity(GO:0003918) DNA topoisomerase II activity(GO:0061505)
0.0	0.2	GO:0051400	BH domain binding(GO:0051400)
0.0	0.1	GO:0031957	very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.0	0.1	GO:0070492	oligosaccharide binding(GO:0070492)
0.0	0.1	GO:0016312	inositol bisphosphate phosphatase activity(GO:0016312)
0.0	0.3	GO:0030276	clathrin binding(GO:0030276)
0.0	0.1	GO:0008179	adenylate cyclase binding(GO:0008179)
0.0	0.4	GO:0005095	GTPase inhibitor activity(GO:0005095)
0.0	0.4	GO:0004697	protein kinase C activity(GO:0004697)
0.0	0.1	GO:0000247	C-8 sterol isomerase activity(GO:0000247)
0.0	0.2	GO:0031434	mitogen-activated protein kinase kinase binding(GO:0031434)
0.0	0.2	GO:0004994	somatostatin receptor activity(GO:0004994)
0.0	0.1	GO:0016417	S-acyltransferase activity(GO:0016417)
0.0	0.2	GO:0004767	sphingomyelin phosphodiesterase activity(GO:0004767)
0.0	0.1	GO:0047499	calcium-independent phospholipase A2 activity(GO:0047499)
0.0	0.1	GO:0003960	NADPH:quinone reductase activity(GO:0003960)
0.0	0.2	GO:0016175	superoxide-generating NADPH oxidase activity(GO:0016175)
0.0	0.2	GO:0009922	fatty acid elongase activity(GO:0009922)
0.0	0.2	GO:0008266	poly(U) RNA binding(GO:0008266)
0.0	0.1	GO:0004999	vasoactive intestinal polypeptide receptor activity(GO:0004999)
0.0	0.1	GO:0030375	thyroid hormone receptor coactivator activity(GO:0030375)
0.0	0.1	GO:0043533	inositol 1,3,4,5 tetrakisphosphate binding(GO:0043533)
0.0	0.1	GO:0033300	dehydroascorbic acid transporter activity(GO:0033300)
0.0	0.1	GO:0035005	1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.0	0.1	GO:0031404	chloride ion binding(GO:0031404)
0.0	0.1	GO:0004596	peptide alpha-N-acetyltransferase activity(GO:0004596)
0.0	0.5	GO:0043621	protein self-association(GO:0043621)
0.0	0.0	GO:0042806	fucose binding(GO:0042806)
0.0	0.1	GO:0070087	chromo shadow domain binding(GO:0070087)
0.0	0.1	GO:0016416	carnitine O-palmitoyltransferase activity(GO:0004095) O-palmitoyltransferase activity(GO:0016416)
0.0	0.2	GO:0005522	profilin binding(GO:0005522)
0.0	0.1	GO:0050664	oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor(GO:0050664)
0.0	0.3	GO:0032452	histone demethylase activity(GO:0032452)
0.0	0.1	GO:0008321	Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.0	0.2	GO:0019864	IgG binding(GO:0019864)
0.0	0.1	GO:0031014	troponin T binding(GO:0031014)
0.0	0.1	GO:0004886	9-cis retinoic acid receptor activity(GO:0004886)
0.0	0.1	GO:0043422	protein kinase B binding(GO:0043422)
0.0	0.1	GO:0047756	chondroitin 4-sulfotransferase activity(GO:0047756)
0.0	0.1	GO:0004704	NF-kappaB-inducing kinase activity(GO:0004704)
0.0	0.1	GO:0070053	thrombospondin receptor activity(GO:0070053)
0.0	0.1	GO:0003997	acyl-CoA oxidase activity(GO:0003997)
0.0	0.0	GO:0052659	inositol-1,4,5-trisphosphate 5-phosphatase activity(GO:0052658) inositol-1,3,4,5-tetrakisphosphate 5-phosphatase activity(GO:0052659)
0.0	0.1	GO:0046934	phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) phosphatidylinositol bisphosphate kinase activity(GO:0052813)
0.0	0.8	GO:0042826	histone deacetylase binding(GO:0042826)
0.0	0.3	GO:0043027	cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.0	0.1	GO:0015095	magnesium ion transmembrane transporter activity(GO:0015095)
0.0	0.1	GO:0061630	ubiquitin-ubiquitin ligase activity(GO:0034450) ubiquitin protein ligase activity(GO:0061630) ubiquitin-like protein ligase activity(GO:0061659)
0.0	0.1	GO:0008174	mRNA methyltransferase activity(GO:0008174)
0.0	0.1	GO:0035197	siRNA binding(GO:0035197)
0.0	0.1	GO:0046404	ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity(GO:0046404) polydeoxyribonucleotide kinase activity(GO:0051733) ATP-dependent polynucleotide kinase activity(GO:0051734)
0.0	0.1	GO:0004563	beta-N-acetylhexosaminidase activity(GO:0004563)
0.0	1.0	GO:0005070	SH3/SH2 adaptor activity(GO:0005070)
0.0	0.1	GO:0003836	beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.0	0.3	GO:0016892	endoribonuclease activity, producing 3'-phosphomonoesters(GO:0016892)
0.0	0.1	GO:0034190	apolipoprotein receptor binding(GO:0034190)
0.0	0.1	GO:0031013	troponin I binding(GO:0031013)
0.0	0.1	GO:0055106	ligase regulator activity(GO:0055103) ubiquitin-protein transferase regulator activity(GO:0055106)
0.0	0.1	GO:0004465	lipoprotein lipase activity(GO:0004465)
0.0	0.1	GO:0050897	cobalt ion binding(GO:0050897)
0.0	0.1	GO:0051766	inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440) inositol trisphosphate kinase activity(GO:0051766)
0.0	0.2	GO:0004950	G-protein coupled chemoattractant receptor activity(GO:0001637) chemokine receptor activity(GO:0004950)
0.0	0.2	GO:0004579	dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.0	0.3	GO:0005086	ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0	0.1	GO:0004126	cytidine deaminase activity(GO:0004126)
0.0	0.1	GO:0070402	NADPH binding(GO:0070402)
0.0	0.1	GO:0004476	mannose-6-phosphate isomerase activity(GO:0004476)
0.0	0.1	GO:0015349	thyroid hormone transmembrane transporter activity(GO:0015349)
0.0	0.1	GO:0004514	nicotinate-nucleotide diphosphorylase (carboxylating) activity(GO:0004514)
0.0	0.1	GO:0004875	complement receptor activity(GO:0004875)
0.0	0.0	GO:0016019	peptidoglycan receptor activity(GO:0016019)
0.0	0.1	GO:0050733	RS domain binding(GO:0050733)
0.0	0.1	GO:0015194	L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.0	0.1	GO:0032405	MutLalpha complex binding(GO:0032405)
0.0	0.2	GO:0034593	phosphatidylinositol bisphosphate phosphatase activity(GO:0034593)
0.0	0.1	GO:0004301	epoxide hydrolase activity(GO:0004301)
0.0	0.0	GO:0019763	immunoglobulin receptor activity(GO:0019763)
0.0	0.1	GO:0003910	DNA ligase activity(GO:0003909) DNA ligase (ATP) activity(GO:0003910)
0.0	0.1	GO:0003986	acetyl-CoA hydrolase activity(GO:0003986)
0.0	0.3	GO:0008373	sialyltransferase activity(GO:0008373)
0.0	0.3	GO:0019198	transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.0	0.0	GO:0019958	C-X-C chemokine binding(GO:0019958) interleukin-8 binding(GO:0019959)
0.0	0.1	GO:0004904	interferon receptor activity(GO:0004904)
0.0	0.1	GO:0005087	Ran guanyl-nucleotide exchange factor activity(GO:0005087)
0.0	0.2	GO:0046625	sphingolipid binding(GO:0046625)
0.0	0.0	GO:0010861	thyroid hormone receptor activator activity(GO:0010861)
0.0	0.1	GO:0042834	peptidoglycan binding(GO:0042834)
0.0	0.1	GO:0015232	heme transporter activity(GO:0015232)
0.0	0.2	GO:0005246	calcium channel regulator activity(GO:0005246)
0.0	0.0	GO:0033829	O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.0	0.1	GO:0005219	ryanodine-sensitive calcium-release channel activity(GO:0005219)
0.0	0.1	GO:0004597	peptide-aspartate beta-dioxygenase activity(GO:0004597)
0.0	0.0	GO:0008184	glycogen phosphorylase activity(GO:0008184)
0.0	0.0	GO:0000400	four-way junction DNA binding(GO:0000400)
0.0	0.0	GO:0071208	histone pre-mRNA DCP binding(GO:0071208)
0.0	0.1	GO:0008517	folic acid transporter activity(GO:0008517)
0.0	0.1	GO:0004568	chitinase activity(GO:0004568)
0.0	0.0	GO:0030292	protein tyrosine kinase inhibitor activity(GO:0030292)
0.0	0.0	GO:0004735	pyrroline-5-carboxylate reductase activity(GO:0004735)
0.0	0.1	GO:0047023	androsterone dehydrogenase activity(GO:0047023)
0.0	0.0	GO:0098518	polynucleotide phosphatase activity(GO:0098518)
0.0	0.0	GO:0004370	glycerol kinase activity(GO:0004370)
0.0	0.0	GO:0004591	oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591)
0.0	0.3	GO:0004864	protein phosphatase inhibitor activity(GO:0004864)
0.0	0.0	GO:0002060	purine nucleobase binding(GO:0002060)
0.0	0.1	GO:0004983	neuropeptide Y receptor activity(GO:0004983)
0.0	0.1	GO:0035381	extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
0.0	0.0	GO:0000268	peroxisome targeting sequence binding(GO:0000268)
0.0	0.2	GO:0016805	dipeptidase activity(GO:0016805)
0.0	0.0	GO:0008559	xenobiotic-transporting ATPase activity(GO:0008559) xenobiotic transporter activity(GO:0042910)
0.0	0.1	GO:0034739	histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041) histone deacetylase activity (H4-K16 specific)(GO:0034739) NAD-dependent histone deacetylase activity (H4-K16 specific)(GO:0046970)
0.0	0.2	GO:0016505	peptidase activator activity involved in apoptotic process(GO:0016505)
0.0	0.2	GO:0004708	MAP kinase kinase activity(GO:0004708)
0.0	0.1	GO:0016778	diphosphotransferase activity(GO:0016778)
0.0	0.1	GO:0052650	NADP-retinol dehydrogenase activity(GO:0052650)
0.0	0.1	GO:0008568	microtubule-severing ATPase activity(GO:0008568)
0.0	0.0	GO:0004449	isocitrate dehydrogenase (NAD+) activity(GO:0004449)
0.0	0.0	GO:0003726	double-stranded RNA adenosine deaminase activity(GO:0003726)
0.0	0.0	GO:0004466	long-chain-acyl-CoA dehydrogenase activity(GO:0004466)
0.0	0.1	GO:0015925	galactosidase activity(GO:0015925)
0.0	0.0	GO:0005220	inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.0	0.0	GO:0003953	NAD+ nucleosidase activity(GO:0003953)
0.0	0.1	GO:0005432	calcium:sodium antiporter activity(GO:0005432)
0.0	0.1	GO:0003709	obsolete RNA polymerase III transcription factor activity(GO:0003709)
0.0	0.1	GO:0048406	nerve growth factor binding(GO:0048406)
0.0	0.0	GO:0032794	GTPase activating protein binding(GO:0032794)
0.0	0.2	GO:0043014	alpha-tubulin binding(GO:0043014)
0.0	0.1	GO:0004815	aspartate-tRNA ligase activity(GO:0004815)
0.0	0.1	GO:0051787	misfolded protein binding(GO:0051787)
0.0	0.1	GO:0031701	angiotensin receptor binding(GO:0031701)
0.0	0.1	GO:0004308	exo-alpha-sialidase activity(GO:0004308) alpha-sialidase activity(GO:0016997)
0.0	0.0	GO:0044020	histone methyltransferase activity (H4-R3 specific)(GO:0044020)
0.0	0.0	GO:0030343	vitamin D3 25-hydroxylase activity(GO:0030343) vitamin D 25-hydroxylase activity(GO:0070643)
0.0	0.1	GO:0017127	cholesterol transporter activity(GO:0017127)
0.0	0.0	GO:0042608	T cell receptor binding(GO:0042608)
0.0	0.1	GO:0016833	oxo-acid-lyase activity(GO:0016833)
0.0	0.1	GO:0008467	[heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.0	0.4	GO:0018024	histone-lysine N-methyltransferase activity(GO:0018024)
0.0	0.0	GO:0043028	cysteine-type endopeptidase regulator activity involved in apoptotic process(GO:0043028)
0.0	0.1	GO:0016944	obsolete RNA polymerase II transcription elongation factor activity(GO:0016944)
0.0	0.0	GO:0043141	ATP-dependent 5'-3' DNA helicase activity(GO:0043141)
0.0	0.1	GO:0016165	linoleate 13S-lipoxygenase activity(GO:0016165)
0.0	0.0	GO:0031685	adenosine receptor binding(GO:0031685)
0.0	0.0	GO:0031177	phosphopantetheine binding(GO:0031177)
0.0	0.3	GO:0001608	G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.0	0.0	GO:0035586	purinergic receptor activity(GO:0035586)
0.0	0.0	GO:0043008	ATP-dependent protein binding(GO:0043008)
0.0	0.3	GO:0002039	p53 binding(GO:0002039)
0.0	0.3	GO:0016831	carboxy-lyase activity(GO:0016831)
0.0	0.1	GO:0000062	fatty-acyl-CoA binding(GO:0000062)
0.0	0.0	GO:0004477	methenyltetrahydrofolate cyclohydrolase activity(GO:0004477)
0.0	0.0	GO:0035198	miRNA binding(GO:0035198)
0.0	0.1	GO:0015385	sodium:proton antiporter activity(GO:0015385)
0.0	0.0	GO:0001640	adenylate cyclase inhibiting G-protein coupled glutamate receptor activity(GO:0001640) G-protein coupled glutamate receptor activity(GO:0098988)
0.0	0.0	GO:0005113	patched binding(GO:0005113)
0.0	0.1	GO:0033170	DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.0	0.0	GO:0015278	calcium-release channel activity(GO:0015278) ligand-gated calcium channel activity(GO:0099604)
0.0	0.2	GO:0070566	adenylyltransferase activity(GO:0070566)
0.0	0.0	GO:0016309	1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
0.0	0.1	GO:0032393	MHC class I receptor activity(GO:0032393)
0.0	0.1	GO:0003688	DNA replication origin binding(GO:0003688)
0.0	0.3	GO:0003725	double-stranded RNA binding(GO:0003725)
0.0	0.1	GO:0008889	glycerophosphodiester phosphodiesterase activity(GO:0008889)
0.0	0.1	GO:0016723	oxidoreductase activity, oxidizing metal ions, NAD or NADP as acceptor(GO:0016723)
0.0	0.2	GO:0004435	phosphatidylinositol phospholipase C activity(GO:0004435)
0.0	0.1	GO:0004908	interleukin-1 receptor activity(GO:0004908)
0.0	0.2	GO:0030552	cAMP binding(GO:0030552)
0.0	0.1	GO:0017040	ceramidase activity(GO:0017040)
0.0	0.0	GO:0015379	potassium:chloride symporter activity(GO:0015379)
0.0	0.2	GO:0004889	acetylcholine-activated cation-selective channel activity(GO:0004889)
0.0	0.0	GO:0008379	thioredoxin peroxidase activity(GO:0008379)
0.0	0.1	GO:0042043	neurexin family protein binding(GO:0042043)
0.0	0.0	GO:0015562	efflux transmembrane transporter activity(GO:0015562)
0.0	0.0	GO:0005025	transforming growth factor beta receptor activity, type I(GO:0005025)
0.0	0.0	GO:0004607	phosphatidylcholine-sterol O-acyltransferase activity(GO:0004607)
0.0	0.1	GO:0051635	obsolete bacterial cell surface binding(GO:0051635)
0.0	0.1	GO:0051019	mitogen-activated protein kinase binding(GO:0051019)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	1.0	PID TCR JNK PATHWAY	JNK signaling in the CD4+ TCR pathway
0.0	0.2	PID CD8 TCR PATHWAY	TCR signaling in naïve CD8+ T cells
0.0	0.2	PID INTEGRIN3 PATHWAY	Beta3 integrin cell surface interactions
0.0	0.4	SA PTEN PATHWAY	PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.0	0.8	PID IL2 STAT5 PATHWAY	IL2 signaling events mediated by STAT5
0.0	0.2	ST PAC1 RECEPTOR PATHWAY	PAC1 Receptor Pathway
0.0	0.3	PID PRL SIGNALING EVENTS PATHWAY	Signaling events mediated by PRL
0.0	0.2	PID IL5 PATHWAY	IL5-mediated signaling events
0.0	1.2	PID TCR PATHWAY	TCR signaling in naïve CD4+ T cells
0.0	0.3	SA B CELL RECEPTOR COMPLEXES	Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.0	0.4	PID EPO PATHWAY	EPO signaling pathway
0.0	0.3	PID ERB GENOMIC PATHWAY	Validated nuclear estrogen receptor beta network
0.0	0.2	PID GMCSF PATHWAY	GMCSF-mediated signaling events
0.0	0.2	SA PROGRAMMED CELL DEATH	Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.0	0.2	PID IL12 STAT4 PATHWAY	IL12 signaling mediated by STAT4
0.0	0.4	PID INTEGRIN A4B1 PATHWAY	Alpha4 beta1 integrin signaling events
0.0	0.0	PID TCR RAS PATHWAY	Ras signaling in the CD4+ TCR pathway
0.0	0.0	PID IL8 CXCR1 PATHWAY	IL8- and CXCR1-mediated signaling events
0.0	0.4	PID IL8 CXCR2 PATHWAY	IL8- and CXCR2-mediated signaling events
0.0	0.5	PID NFAT 3PATHWAY	Role of Calcineurin-dependent NFAT signaling in lymphocytes
0.0	0.2	PID P38 MK2 PATHWAY	p38 signaling mediated by MAPKAP kinases
0.0	0.0	PID ERBB NETWORK PATHWAY	ErbB receptor signaling network
0.0	0.5	PID HDAC CLASSII PATHWAY	Signaling events mediated by HDAC Class II
0.0	0.5	PID CASPASE PATHWAY	Caspase cascade in apoptosis
0.0	0.3	PID P38 MKK3 6PATHWAY	p38 MAPK signaling pathway
0.0	0.1	PID CD40 PATHWAY	CD40/CD40L signaling
0.0	0.5	PID RAC1 PATHWAY	RAC1 signaling pathway
0.0	0.2	SA CASPASE CASCADE	Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.0	0.2	PID ARF6 PATHWAY	Arf6 signaling events
0.0	0.0	ST GRANULE CELL SURVIVAL PATHWAY	Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway.
0.0	0.6	PID MET PATHWAY	Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)
0.0	0.3	PID FCER1 PATHWAY	Fc-epsilon receptor I signaling in mast cells
0.0	0.0	PID REELIN PATHWAY	Reelin signaling pathway
0.0	0.1	ST TYPE I INTERFERON PATHWAY	Type I Interferon (alpha/beta IFN) Pathway
0.0	0.1	PID ERBB4 PATHWAY	ErbB4 signaling events
0.0	0.0	SIG PIP3 SIGNALING IN CARDIAC MYOCTES	Genes related to PIP3 signaling in cardiac myocytes
0.0	0.3	PID NFAT TFPATHWAY	Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0	0.2	PID P38 ALPHA BETA DOWNSTREAM PATHWAY	Signaling mediated by p38-alpha and p38-beta
0.0	0.1	SA MMP CYTOKINE CONNECTION	Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0	0.2	PID IL6 7 PATHWAY	IL6-mediated signaling events
0.0	0.2	SIG PIP3 SIGNALING IN B LYMPHOCYTES	Genes related to PIP3 signaling in B lymphocytes
0.0	0.0	SA FAS SIGNALING	The TNF-type receptor Fas induces apoptosis on ligand binding.
0.0	0.3	PID HIF2PATHWAY	HIF-2-alpha transcription factor network
0.0	0.0	PID S1P S1P2 PATHWAY	S1P2 pathway
0.0	0.2	PID IL1 PATHWAY	IL1-mediated signaling events
0.0	0.3	PID ATM PATHWAY	ATM pathway
0.0	0.0	PID RANBP2 PATHWAY	Sumoylation by RanBP2 regulates transcriptional repression
0.0	0.1	PID PI3KCI PATHWAY	Class I PI3K signaling events
0.0	0.0	PID RAC1 REG PATHWAY	Regulation of RAC1 activity
0.0	0.1	ST TUMOR NECROSIS FACTOR PATHWAY	Tumor Necrosis Factor Pathway.
0.0	0.1	SIG CD40PATHWAYMAP	Genes related to CD40 signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.2	REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS	Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.0	0.5	REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS	Genes involved in Signal regulatory protein (SIRP) family interactions
0.0	1.2	REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS	Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.0	0.1	REACTOME BINDING AND ENTRY OF HIV VIRION	Genes involved in Binding and entry of HIV virion
0.0	0.4	REACTOME THE NLRP3 INFLAMMASOME	Genes involved in The NLRP3 inflammasome
0.0	0.3	REACTOME ALPHA LINOLENIC ACID ALA METABOLISM	Genes involved in alpha-linolenic acid (ALA) metabolism
0.0	0.7	REACTOME GENERATION OF SECOND MESSENGER MOLECULES	Genes involved in Generation of second messenger molecules
0.0	0.4	REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS	Genes involved in Trafficking of GluR2-containing AMPA receptors
0.0	0.4	REACTOME N GLYCAN ANTENNAE ELONGATION	Genes involved in N-Glycan antennae elongation
0.0	0.1	REACTOME INFLAMMASOMES	Genes involved in Inflammasomes
0.0	0.2	REACTOME ENDOSOMAL VACUOLAR PATHWAY	Genes involved in Endosomal/Vacuolar pathway
0.0	0.3	REACTOME THE ROLE OF NEF IN HIV1 REPLICATION AND DISEASE PATHOGENESIS	Genes involved in The role of Nef in HIV-1 replication and disease pathogenesis
0.0	0.0	REACTOME PLATELET SENSITIZATION BY LDL	Genes involved in Platelet sensitization by LDL
0.0	0.3	REACTOME ENOS ACTIVATION AND REGULATION	Genes involved in eNOS activation and regulation
0.0	0.7	REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS	Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.0	0.5	REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE	Genes involved in Sema4D induced cell migration and growth-cone collapse
0.0	0.2	REACTOME ACTIVATION OF RAC	Genes involved in Activation of Rac
0.0	0.3	REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES	Genes involved in Cytosolic sulfonation of small molecules
0.0	0.9	REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL	Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0	0.3	REACTOME GPVI MEDIATED ACTIVATION CASCADE	Genes involved in GPVI-mediated activation cascade
0.0	0.3	REACTOME G1 PHASE	Genes involved in G1 Phase
0.0	0.8	REACTOME INTERFERON GAMMA SIGNALING	Genes involved in Interferon gamma signaling
0.0	0.1	REACTOME REGULATION OF SIGNALING BY CBL	Genes involved in Regulation of signaling by CBL
0.0	0.2	REACTOME INITIAL TRIGGERING OF COMPLEMENT	Genes involved in Initial triggering of complement
0.0	0.4	REACTOME RORA ACTIVATES CIRCADIAN EXPRESSION	Genes involved in RORA Activates Circadian Expression
0.0	0.2	REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION	Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.0	0.1	REACTOME GRB2 SOS PROVIDES LINKAGE TO MAPK SIGNALING FOR INTERGRINS	Genes involved in GRB2:SOS provides linkage to MAPK signaling for Intergrins
0.0	0.4	REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING	Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.0	0.3	REACTOME EFFECTS OF PIP2 HYDROLYSIS	Genes involved in Effects of PIP2 hydrolysis
0.0	0.2	REACTOME REPAIR SYNTHESIS FOR GAP FILLING BY DNA POL IN TC NER	Genes involved in Repair synthesis for gap-filling by DNA polymerase in TC-NER
0.0	0.2	REACTOME REGULATION OF COMPLEMENT CASCADE	Genes involved in Regulation of Complement cascade
0.0	0.1	REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX UPON TLR7 8 OR 9 STIMULATION	Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
0.0	0.2	REACTOME PKA MEDIATED PHOSPHORYLATION OF CREB	Genes involved in PKA-mediated phosphorylation of CREB
0.0	0.5	REACTOME GLYCOSPHINGOLIPID METABOLISM	Genes involved in Glycosphingolipid metabolism
0.0	0.1	REACTOME COMMON PATHWAY	Genes involved in Common Pathway
0.0	0.7	REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES	Genes involved in Chemokine receptors bind chemokines
0.0	0.1	REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING	Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
0.0	0.1	REACTOME DSCAM INTERACTIONS	Genes involved in DSCAM interactions
0.0	0.2	REACTOME IL RECEPTOR SHC SIGNALING	Genes involved in Interleukin receptor SHC signaling
0.0	0.2	REACTOME METABOLISM OF PORPHYRINS	Genes involved in Metabolism of porphyrins
0.0	0.0	REACTOME NFKB ACTIVATION THROUGH FADD RIP1 PATHWAY MEDIATED BY CASPASE 8 AND10	Genes involved in NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10
0.0	0.2	REACTOME INTRINSIC PATHWAY	Genes involved in Intrinsic Pathway
0.0	0.1	REACTOME TRAF6 MEDIATED NFKB ACTIVATION	Genes involved in TRAF6 mediated NF-kB activation
0.0	0.0	REACTOME RIP MEDIATED NFKB ACTIVATION VIA DAI	Genes involved in RIP-mediated NFkB activation via DAI
0.0	0.2	REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY	Genes involved in Post-chaperonin tubulin folding pathway
0.0	0.2	REACTOME G0 AND EARLY G1	Genes involved in G0 and Early G1
0.0	0.1	REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS	Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.0	0.0	REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION	Genes involved in activated TAK1 mediates p38 MAPK activation
0.0	0.2	REACTOME RECYCLING PATHWAY OF L1	Genes involved in Recycling pathway of L1
0.0	0.1	REACTOME HIGHLY CALCIUM PERMEABLE POSTSYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS	Genes involved in Highly calcium permeable postsynaptic nicotinic acetylcholine receptors
0.0	0.1	REACTOME GAP JUNCTION DEGRADATION	Genes involved in Gap junction degradation
0.0	0.0	REACTOME PEPTIDE HORMONE BIOSYNTHESIS	Genes involved in Peptide hormone biosynthesis
0.0	0.2	REACTOME KERATAN SULFATE BIOSYNTHESIS	Genes involved in Keratan sulfate biosynthesis
0.0	0.0	REACTOME INTEGRATION OF PROVIRUS	Genes involved in Integration of provirus
0.0	0.1	REACTOME P38MAPK EVENTS	Genes involved in p38MAPK events
0.0	0.1	REACTOME IRAK1 RECRUITS IKK COMPLEX	Genes involved in IRAK1 recruits IKK complex
0.0	0.1	REACTOME SIGNALING BY FGFR1 FUSION MUTANTS	Genes involved in Signaling by FGFR1 fusion mutants
0.0	0.0	REACTOME G PROTEIN ACTIVATION	Genes involved in G-protein activation
0.0	0.0	REACTOME SIGNALING BY ERBB2	Genes involved in Signaling by ERBB2