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ENCODE: H3K4me1 ChIP-Seq of primary human cells
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CREMA is a free online tool that recognizes most important transcription factors that change the chromatin state across different samples.

Results for PGR

Z-value: 2.57

Motif logo

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Transcription factors associated with PGR

Gene Symbol Gene ID Gene Info
ENSG00000082175.10 PGR

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE Gene Distance Association probability Pearson corr. coef. P-value Plot
PGRchr11_100998153_10099841015200.552946-0.818.4e-03Click!
PGRchr11_100998762_1009989139640.707522-0.561.2e-01Click!
PGRchr11_100998523_10099867412030.631733-0.551.2e-01Click!
PGRchr11_100997860_10099801118660.490919-0.511.6e-01Click!

Activity of the PGR motif across conditions

Conditions sorted by the z-value of the PGR motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE) Target Score Top associated gene Gene Info Distance of CRE to TSS CRE/Gene association probability
chr22_40719905_40720423 0.44 ADSL
adenylosuccinate lyase
22343
0.17
chr2_47393877_47394028 0.41 CALM2
calmodulin 2 (phosphorylase kinase, delta)
9698
0.2
chr8_941660_941943 0.41 ERICH1-AS1
ERICH1 antisense RNA 1
108473
0.08
chr2_135029441_135029730 0.40 MGAT5
mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase
17755
0.24
chr11_108114766_108115122 0.40 ENSG00000206967
.
14613
0.15
chr20_51025367_51025552 0.40 ZFP64
ZFP64 zinc finger protein
216934
0.02
chr9_92151633_92152777 0.39 SEMA4D
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D
39160
0.16
chr4_4462558_4462851 0.38 STX18
syntaxin 18
977
0.59
chr10_80897727_80898445 0.38 ZMIZ1
zinc finger, MIZ-type containing 1
69294
0.12
chr1_9789105_9789546 0.37 PIK3CD
phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta
11198
0.17
chr3_10295585_10295736 0.37 TATDN2
TatD DNase domain containing 2
5064
0.14
chr10_75619235_75619680 0.36 CAMK2G
calcium/calmodulin-dependent protein kinase II gamma
1155
0.34
chr6_143862361_143862526 0.36 PHACTR2
phosphatase and actin regulator 2
4461
0.19
chr13_111837384_111838319 0.36 ARHGEF7
Rho guanine nucleotide exchange factor (GEF) 7
566
0.79
chr4_107274416_107274677 0.36 TBCK
TBC1 domain containing kinase
31894
0.19
chr9_136006860_136007130 0.36 RALGDS
ral guanine nucleotide dissociation stimulator
491
0.74
chr10_72193939_72194090 0.35 AC022532.1
Uncharacterized protein
571
0.72
chr4_15644909_15645060 0.35 FBXL5
F-box and leucine-rich repeat protein 5
1288
0.49
chr16_84858002_84858153 0.35 RP11-254F19.2

3792
0.21
chr6_45981609_45981857 0.35 CLIC5
chloride intracellular channel 5
1832
0.38
chr6_16420351_16420774 0.35 ENSG00000265642
.
8192
0.31
chr3_188156360_188156537 0.35 LPP-AS1
LPP antisense RNA 1
130006
0.05
chr17_8053906_8054187 0.34 PER1
period circadian clock 1
104
0.92
chr11_60878524_60878675 0.34 CD5
CD5 molecule
8618
0.18
chr9_92022718_92022899 0.34 SEMA4D
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D
1967
0.41
chr2_113943413_113943847 0.34 PSD4
pleckstrin and Sec7 domain containing 4
10227
0.14
chr12_52071969_52072120 0.34 SCN8A
sodium channel, voltage gated, type VIII, alpha subunit
8163
0.27
chr5_39181205_39181356 0.34 FYB
FYN binding protein
21849
0.24
chr2_201924015_201924238 0.34 NDUFB3
NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 3, 12kDa
12030
0.13
chr2_202113259_202113410 0.33 CASP8
caspase 8, apoptosis-related cysteine peptidase
9369
0.19
chr20_50028653_50029381 0.33 ENSG00000263645
.
35159
0.18
chr2_136810090_136810241 0.33 AC093391.2

40130
0.17
chr11_128168877_128169065 0.33 ETS1
v-ets avian erythroblastosis virus E26 oncogene homolog 1
206318
0.03
chr3_56823289_56823680 0.33 ARHGEF3
Rho guanine nucleotide exchange factor (GEF) 3
12493
0.28
chr8_82002361_82002551 0.33 PAG1
phosphoprotein associated with glycosphingolipid microdomains 1
21847
0.26
chr5_130667286_130667437 0.33 CDC42SE2
CDC42 small effector 2
53938
0.17
chr10_28835021_28835418 0.33 WAC
WW domain containing adaptor with coiled-coil
12167
0.2
chr7_27404472_27404623 0.33 EVX1-AS
EVX1 antisense RNA
117699
0.04
chr1_25320280_25320441 0.32 RUNX3
runt-related transcription factor 3
28859
0.16
chr2_30471681_30471976 0.32 LBH
limb bud and heart development
16782
0.23
chr2_204577764_204577915 0.32 CD28
CD28 molecule
6423
0.26
chr8_134562977_134563358 0.32 ST3GAL1
ST3 beta-galactoside alpha-2,3-sialyltransferase 1
20925
0.27
chr7_151840289_151840485 0.32 KMT2C
lysine (K)-specific methyltransferase 2C
503
0.8
chr7_142155820_142156296 0.32 PRSS3P3
protease, serine, 3 pseudogene 3
166449
0.03
chr5_150526605_150526923 0.32 ANXA6
annexin A6
4276
0.24
chr13_41151912_41152184 0.32 AL133318.1
Uncharacterized protein
40725
0.18
chr8_101823524_101823815 0.31 ENSG00000222795
.
20419
0.17
chr16_50802521_50802672 0.31 CYLD
cylindromatosis (turban tumor syndrome)
19136
0.11
chr9_114604147_114604298 0.31 ENSG00000206907
.
2114
0.34
chr11_3760141_3760292 0.31 NUP98
nucleoporin 98kDa
21608
0.1
chr2_113925026_113925412 0.31 PSD4
pleckstrin and Sec7 domain containing 4
6329
0.15
chr8_133990678_133991177 0.31 TG
thyroglobulin
14075
0.25
chr3_16350029_16350306 0.31 RP11-415F23.2

5779
0.18
chr12_47004551_47004702 0.31 SLC38A4
solute carrier family 38, member 4
158461
0.04
chr3_69145351_69145608 0.31 ARL6IP5
ADP-ribosylation-like factor 6 interacting protein 5
11307
0.14
chr8_134303253_134303609 0.30 NDRG1
N-myc downstream regulated 1
5348
0.28
chr15_66687099_66687308 0.30 MAP2K1
mitogen-activated protein kinase kinase 1
8048
0.13
chr1_117917956_117918139 0.30 MAN1A2
mannosidase, alpha, class 1A, member 2
7976
0.3
chr7_148609620_148609917 0.30 ENSG00000239468
.
22462
0.13
chr9_113662694_113662845 0.30 ENSG00000206923
.
2848
0.32
chr10_44312151_44312815 0.30 ZNF32
zinc finger protein 32
168179
0.03
chr20_37491189_37491977 0.30 ENSG00000240474
.
9830
0.2
chrX_78522662_78522933 0.30 GPR174
G protein-coupled receptor 174
96328
0.09
chr1_90116183_90116334 0.30 LRRC8C
leucine rich repeat containing 8 family, member C
17627
0.16
chr15_60868186_60868595 0.30 RORA
RAR-related orphan receptor A
16350
0.2
chr10_22876646_22876797 0.30 PIP4K2A
phosphatidylinositol-5-phosphate 4-kinase, type II, alpha
3883
0.35
chr10_126437876_126438126 0.29 FAM53B
family with sequence similarity 53, member B
5163
0.18
chr14_71421573_71421779 0.29 PCNX
pecanex homolog (Drosophila)
47220
0.19
chr1_175180078_175180229 0.29 KIAA0040
KIAA0040
18074
0.25
chr18_67610582_67610750 0.29 CD226
CD226 molecule
3989
0.34
chr15_64300635_64300804 0.29 DAPK2
death-associated protein kinase 2
31747
0.16
chr17_48965319_48965470 0.29 TOB1
transducer of ERBB2, 1
20055
0.15
chr16_50102313_50102546 0.29 RP11-429P3.3

2294
0.22
chr1_229461032_229461183 0.29 RP4-803J11.2

5957
0.15
chr3_171094795_171095167 0.29 ENSG00000222506
.
62334
0.13
chr2_231196155_231196306 0.29 SP140L
SP140 nuclear body protein-like
4245
0.28
chr14_96593461_96593715 0.29 ENSG00000221236
.
9600
0.19
chr14_99693708_99693994 0.29 AL109767.1

35434
0.17
chr6_108059944_108060120 0.28 SCML4
sex comb on midleg-like 4 (Drosophila)
6433
0.31
chr11_6548040_6548191 0.28 DNHD1
dynein heavy chain domain 1
28669
0.09
chr14_94624184_94624480 0.28 PPP4R4
protein phosphatase 4, regulatory subunit 4
11867
0.17
chr12_12626986_12627137 0.28 DUSP16
dual specificity phosphatase 16
46998
0.15
chr20_43522738_43522936 0.28 YWHAB
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta
8444
0.15
chr7_149543340_149543491 0.28 ZNF862
zinc finger protein 862
7951
0.17
chr17_81028924_81029552 0.28 METRNL
meteorin, glial cell differentiation regulator-like
8329
0.22
chr2_106394710_106394861 0.28 NCK2
NCK adaptor protein 2
32597
0.22
chr7_76921945_76922096 0.28 GSAP
gamma-secretase activating protein
33543
0.17
chr13_42968762_42968913 0.28 AKAP11
A kinase (PRKA) anchor protein 11
122548
0.06
chr9_97589360_97589511 0.28 RP11-49O14.3

2881
0.25
chr6_147644361_147644521 0.28 STXBP5
syntaxin binding protein 5 (tomosyn)
3868
0.37
chr10_27087573_27087735 0.28 ENSG00000206605
.
8079
0.19
chr10_35374638_35374834 0.28 CUL2
cullin 2
4556
0.18
chr11_114086673_114087539 0.28 NNMT
nicotinamide N-methyltransferase
41447
0.17
chr4_76442938_76443089 0.28 RCHY1
ring finger and CHY zinc finger domain containing 1, E3 ubiquitin protein ligase
3118
0.24
chr14_74516670_74516821 0.28 CCDC176
coiled-coil domain containing 176
5491
0.16
chr5_35790123_35790325 0.28 SPEF2
sperm flagellar 2
10954
0.22
chr22_32876313_32876464 0.27 FBXO7
F-box protein 7
4808
0.21
chr14_107175089_107175555 0.27 IGHV2-70
immunoglobulin heavy variable 2-70
4016
0.05
chr3_150923497_150923774 0.27 GPR171
G protein-coupled receptor 171
2647
0.22
chr2_25495296_25495711 0.27 DNMT3A
DNA (cytosine-5-)-methyltransferase 3 alpha
20323
0.2
chr7_44668438_44669074 0.27 OGDH
oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide)
4695
0.22
chr15_78339069_78339553 0.27 ENSG00000221476
.
8438
0.14
chr14_99659688_99659839 0.27 AL162151.4

35010
0.19
chr6_91001741_91001892 0.27 BACH2
BTB and CNC homology 1, basic leucine zipper transcription factor 2
4645
0.27
chr11_108097039_108097242 0.27 ATM
ataxia telangiectasia mutated
2335
0.22
chr14_61557835_61557986 0.27 SLC38A6
solute carrier family 38, member 6
48042
0.15
chr4_164593002_164593153 0.27 MARCH1
membrane-associated ring finger (C3HC4) 1, E3 ubiquitin protein ligase
58391
0.15
chr14_68792413_68792564 0.27 RAD51B
RAD51 paralog B
85739
0.09
chr3_43796991_43797142 0.27 ABHD5
abhydrolase domain containing 5
43867
0.18
chr8_125575470_125576116 0.27 MTSS1
metastasis suppressor 1
2175
0.26
chr17_26876127_26876878 0.27 UNC119
unc-119 homolog (C. elegans)
85
0.93
chr10_126386807_126387279 0.26 FAM53B-AS1
FAM53B antisense RNA 1
5151
0.23
chr11_110341183_110341334 0.26 FDX1
ferredoxin 1
40651
0.21
chr3_114052154_114052373 0.26 ENSG00000207770
.
16847
0.16
chr3_133209932_133210083 0.26 BFSP2-AS1
BFSP2 antisense RNA 1
35387
0.16
chr13_74705428_74705642 0.26 KLF12
Kruppel-like factor 12
2859
0.42
chr6_112125443_112125653 0.26 FYN
FYN oncogene related to SRC, FGR, YES
5922
0.3
chr3_131520972_131521123 0.26 CPNE4
copine IV
123378
0.06
chrX_23802791_23803324 0.26 SAT1
spermidine/spermine N1-acetyltransferase 1
1767
0.23
chr6_106628525_106628811 0.26 RP1-134E15.3

80653
0.08
chr8_41334799_41334950 0.26 GOLGA7
golgin A7
13041
0.18
chr6_3868238_3868436 0.26 FAM50B
family with sequence similarity 50, member B
18715
0.2
chr14_71124948_71125129 0.26 TTC9
tetratricopeptide repeat domain 9
16534
0.2
chr1_114314007_114314272 0.26 PHTF1
putative homeodomain transcription factor 1
12041
0.18
chr2_162871199_162871350 0.26 AC008063.2

58492
0.12
chr1_100830854_100831005 0.26 CDC14A
cell division cycle 14A
12424
0.18
chr7_38261465_38261616 0.26 STARD3NL
STARD3 N-terminal like
43543
0.2
chr2_197995272_197995665 0.26 ANKRD44
ankyrin repeat domain 44
8011
0.27
chr10_33439132_33439327 0.26 NRP1
neuropilin 1
35354
0.17
chr2_10472354_10472745 0.26 HPCAL1
hippocalcin-like 1
28723
0.15
chr3_46394034_46394455 0.26 CCR2
chemokine (C-C motif) receptor 2
981
0.53
chr2_158273515_158274051 0.26 CYTIP
cytohesin 1 interacting protein
22143
0.2
chr10_112618995_112619585 0.25 PDCD4
programmed cell death 4 (neoplastic transformation inhibitor)
12275
0.14
chr8_124099579_124099969 0.25 TBC1D31
TBC1 domain family, member 31
6127
0.18
chr1_111738933_111739395 0.25 DENND2D
DENN/MADD domain containing 2D
4147
0.14
chr11_112748912_112749352 0.25 RP11-629G13.1

82889
0.09
chr11_64528507_64528709 0.25 PYGM
phosphorylase, glycogen, muscle
839
0.47
chr11_48063752_48063903 0.25 AC103828.1

26420
0.18
chr10_11275555_11276261 0.25 RP3-323N1.2

62569
0.12
chr1_109964305_109964456 0.25 PSMA5
proteasome (prosome, macropain) subunit, alpha type, 5
4593
0.16
chr12_65085302_65085472 0.25 AC025262.1
Mesenchymal stem cell protein DSC96; Uncharacterized protein
4942
0.17
chr13_100032613_100033027 0.25 ENSG00000207719
.
24435
0.18
chr3_105582815_105583041 0.25 CBLB
Cbl proto-oncogene B, E3 ubiquitin protein ligase
4959
0.37
chr14_72061251_72061402 0.25 SIPA1L1
signal-induced proliferation-associated 1 like 1
3625
0.37
chr4_123356495_123356646 0.25 IL2
interleukin 2
21310
0.22
chr1_66741246_66741518 0.25 PDE4B
phosphodiesterase 4B, cAMP-specific
18052
0.28
chr3_196474181_196474332 0.25 ENSG00000272359
.
61
0.96
chr16_3899065_3899268 0.25 CREBBP
CREB binding protein
30955
0.18
chr12_66684119_66684270 0.25 ENSG00000222744
.
2269
0.26
chr8_125884475_125884626 0.25 ENSG00000263735
.
50250
0.14
chr11_66413680_66413831 0.25 RBM4
RNA binding motif protein 4
7349
0.1
chr5_40672680_40672956 0.25 PTGER4
prostaglandin E receptor 4 (subtype EP4)
6782
0.22
chr14_88480135_88480311 0.25 RP11-300J18.2

1732
0.33
chr12_58174546_58174758 0.25 TSFM
Ts translation elongation factor, mitochondrial
1720
0.14
chr1_29492039_29492190 0.25 RP11-242O24.5

13113
0.15
chr14_23000021_23000410 0.24 TRAJ15
T cell receptor alpha joining 15
1635
0.24
chr13_25193371_25193571 0.24 ENSG00000211508
.
10254
0.2
chr19_3950919_3951410 0.24 DAPK3
death-associated protein kinase 3
9993
0.1
chr3_154867378_154867529 0.24 MME-AS1
MME antisense RNA 1
33621
0.22
chr4_140819733_140819884 0.24 MAML3
mastermind-like 3 (Drosophila)
7687
0.29
chr11_60761122_60761414 0.24 ENSG00000207153
.
8629
0.13
chr2_11471370_11471521 0.24 ROCK2
Rho-associated, coiled-coil containing protein kinase 2
13266
0.23
chr2_225806071_225806268 0.24 DOCK10
dedicator of cytokinesis 10
5613
0.32
chr2_85071612_85071979 0.24 TRABD2A
TraB domain containing 2A
36411
0.15
chr17_78786573_78786901 0.24 RP11-28G8.1

7305
0.25
chr4_78744780_78744931 0.24 CNOT6L
CCR4-NOT transcription complex, subunit 6-like
4086
0.3
chr3_112719564_112719819 0.24 GTPBP8
GTP-binding protein 8 (putative)
9277
0.14
chr8_121748012_121748163 0.24 RP11-713M15.1

25406
0.23
chr17_17753098_17753798 0.24 TOM1L2
target of myb1-like 2 (chicken)
12646
0.14
chr15_61135667_61135839 0.24 RP11-554D20.1

78814
0.11
chr11_587585_588264 0.24 PHRF1
PHD and ring finger domains 1
11403
0.07
chr5_14415347_14415596 0.24 TRIO
trio Rho guanine nucleotide exchange factor
73086
0.13
chr3_196404701_196405150 0.24 ENSG00000201441
.
30910
0.1
chr7_32628711_32628871 0.24 AVL9
AVL9 homolog (S. cerevisiase)
45924
0.18
chr15_67407609_67407887 0.24 SMAD3
SMAD family member 3
10306
0.24
chr4_109095665_109095816 0.23 ENSG00000232021
.
1165
0.55
chr10_945205_945384 0.23 LARP4B
La ribonucleoprotein domain family, member 4B
4161
0.24
chr14_72917347_72917498 0.23 RGS6
regulator of G-protein signaling 6
3806
0.38
chr17_46912636_46912982 0.23 CALCOCO2
calcium binding and coiled-coil domain 2
4219
0.14
chr20_57844647_57845067 0.23 EDN3
endothelin 3
30625
0.2
chr3_170982645_170982911 0.23 TNIK
TRAF2 and NCK interacting kinase
39278
0.21
chr15_50194108_50194259 0.23 ATP8B4
ATPase, class I, type 8B, member 4
6107
0.24
chr12_93825039_93825190 0.23 UBE2N
ubiquitin-conjugating enzyme E2N
9918
0.15
chr13_97867179_97867538 0.23 MBNL2
muscleblind-like splicing regulator 2
6330
0.31
chr2_225858106_225858257 0.23 ENSG00000263828
.
17076
0.26
chr6_492948_493099 0.23 RP1-20B11.2

31148
0.23
chr5_93947809_93947960 0.23 CTC-303L1.2

5943
0.18
chr14_61965734_61966388 0.23 RP11-47I22.4

29785
0.17
chr10_104555085_104555236 0.23 ENSG00000252994
.
8526
0.14
chr6_139484130_139484281 0.23 HECA
headcase homolog (Drosophila)
27956
0.2
chr8_19414017_19414313 0.23 CSGALNACT1
chondroitin sulfate N-acetylgalactosaminyltransferase 1
45211
0.2
chr1_111182407_111182558 0.23 KCNA2
potassium voltage-gated channel, shaker-related subfamily, member 2
8386
0.18
chr8_128137659_128137810 0.23 POU5F1B
POU class 5 homeobox 1B
288801
0.01
chr4_143271202_143271432 0.23 INPP4B
inositol polyphosphate-4-phosphatase, type II, 105kDa
44220
0.22
chr2_175500944_175501126 0.23 WIPF1
WAS/WASL interacting protein family, member 1
1728
0.41
chr8_64085269_64085426 0.23 YTHDF3
YTH domain family, member 3
4133
0.3
chr6_131946686_131946837 0.23 MED23
mediator complex subunit 23
2439
0.23
chr1_156814375_156814655 0.23 INSRR
insulin receptor-related receptor
14295
0.11
chr3_18766491_18766692 0.23 ENSG00000228956
.
20645
0.29
chr2_37860606_37860964 0.23 CDC42EP3
CDC42 effector protein (Rho GTPase binding) 3
14016
0.24

Histogram of CRE-TSS distances for CREs targeted by :

Histogram of

Rank distribution of CRE target scores:

Histogram of target CRE score.

Distribution of target CREs across different genomic regions:

Weighted Piechart of Weighted Piechart of Weighted Piechart of

Network of associatons between targets according to the STRING database.

StringDB image

First level regulatory network of PGR

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.5 GO:0032714 negative regulation of interleukin-5 production(GO:0032714)
0.2 0.6 GO:0002669 lymphocyte anergy(GO:0002249) regulation of T cell anergy(GO:0002667) positive regulation of T cell anergy(GO:0002669) T cell anergy(GO:0002870) regulation of lymphocyte anergy(GO:0002911) positive regulation of lymphocyte anergy(GO:0002913)
0.2 0.8 GO:0045589 regulation of regulatory T cell differentiation(GO:0045589)
0.2 0.8 GO:1901339 activation of store-operated calcium channel activity(GO:0032237) regulation of store-operated calcium channel activity(GO:1901339) positive regulation of store-operated calcium channel activity(GO:1901341)
0.2 0.6 GO:0010459 negative regulation of heart rate(GO:0010459)
0.2 0.5 GO:0019276 UDP-N-acetylgalactosamine metabolic process(GO:0019276)
0.1 0.4 GO:0001831 trophectodermal cellular morphogenesis(GO:0001831)
0.1 0.7 GO:0002710 negative regulation of T cell mediated immunity(GO:0002710)
0.1 0.4 GO:0007221 positive regulation of transcription of Notch receptor target(GO:0007221)
0.1 0.5 GO:0043615 astrocyte cell migration(GO:0043615)
0.1 0.4 GO:0018076 N-terminal peptidyl-lysine acetylation(GO:0018076)
0.1 0.1 GO:0042091 interleukin-10 biosynthetic process(GO:0042091) regulation of interleukin-10 biosynthetic process(GO:0045074)
0.1 0.2 GO:0001766 membrane raft polarization(GO:0001766) membrane raft distribution(GO:0031580)
0.1 0.2 GO:0050862 positive regulation of T cell receptor signaling pathway(GO:0050862)
0.1 0.5 GO:0045059 positive thymic T cell selection(GO:0045059)
0.1 0.6 GO:0007172 signal complex assembly(GO:0007172)
0.1 0.7 GO:0002837 regulation of response to tumor cell(GO:0002834) positive regulation of response to tumor cell(GO:0002836) regulation of immune response to tumor cell(GO:0002837) positive regulation of immune response to tumor cell(GO:0002839)
0.1 0.3 GO:0045056 transcytosis(GO:0045056)
0.1 0.2 GO:0002677 negative regulation of chronic inflammatory response(GO:0002677)
0.1 2.5 GO:0050690 regulation of defense response to virus by virus(GO:0050690)
0.1 0.3 GO:0090286 cytoskeletal anchoring at nuclear membrane(GO:0090286)
0.1 0.3 GO:0030854 positive regulation of granulocyte differentiation(GO:0030854)
0.1 0.2 GO:0032656 regulation of interleukin-13 production(GO:0032656)
0.1 0.2 GO:0050710 negative regulation of cytokine secretion(GO:0050710)
0.1 0.4 GO:0042989 sequestering of actin monomers(GO:0042989)
0.1 0.3 GO:0060437 lung growth(GO:0060437)
0.1 0.2 GO:0048861 leukemia inhibitory factor signaling pathway(GO:0048861)
0.1 0.2 GO:0061154 endothelial tube morphogenesis(GO:0061154)
0.1 0.4 GO:0048096 chromatin-mediated maintenance of transcription(GO:0048096)
0.1 0.2 GO:0045722 positive regulation of gluconeogenesis(GO:0045722)
0.1 0.2 GO:0048742 regulation of skeletal muscle fiber development(GO:0048742)
0.1 0.1 GO:0042996 regulation of Golgi to plasma membrane protein transport(GO:0042996)
0.1 0.2 GO:0002313 mature B cell differentiation involved in immune response(GO:0002313)
0.1 0.3 GO:0050687 negative regulation of defense response to virus(GO:0050687)
0.1 0.5 GO:0006491 N-glycan processing(GO:0006491)
0.1 0.4 GO:0006198 cAMP catabolic process(GO:0006198)
0.1 0.2 GO:0035405 histone-threonine phosphorylation(GO:0035405)
0.1 0.1 GO:0002335 mature B cell differentiation(GO:0002335)
0.1 0.7 GO:0051828 entry into host cell(GO:0030260) entry into host(GO:0044409) entry into cell of other organism involved in symbiotic interaction(GO:0051806) entry into other organism involved in symbiotic interaction(GO:0051828)
0.1 0.2 GO:0043383 negative T cell selection(GO:0043383)
0.1 0.1 GO:0019049 evasion or tolerance of host defenses by virus(GO:0019049) avoidance of host defenses(GO:0044413) evasion or tolerance of host defenses(GO:0044415) avoidance of defenses of other organism involved in symbiotic interaction(GO:0051832) evasion or tolerance of defenses of other organism involved in symbiotic interaction(GO:0051834)
0.1 0.1 GO:0033087 negative regulation of immature T cell proliferation(GO:0033087) negative regulation of immature T cell proliferation in thymus(GO:0033088)
0.1 0.5 GO:0043550 regulation of lipid kinase activity(GO:0043550)
0.1 0.1 GO:0072600 protein targeting to Golgi(GO:0000042) establishment of protein localization to Golgi(GO:0072600)
0.1 0.2 GO:0006104 succinyl-CoA metabolic process(GO:0006104)
0.1 0.2 GO:0010761 fibroblast migration(GO:0010761)
0.1 0.1 GO:0010572 positive regulation of platelet activation(GO:0010572)
0.1 0.3 GO:0032733 positive regulation of interleukin-10 production(GO:0032733)
0.1 0.2 GO:0060088 auditory receptor cell morphogenesis(GO:0002093) auditory receptor cell stereocilium organization(GO:0060088)
0.1 0.2 GO:0035066 positive regulation of histone acetylation(GO:0035066) positive regulation of protein acetylation(GO:1901985) positive regulation of peptidyl-lysine acetylation(GO:2000758)
0.1 0.1 GO:0051497 negative regulation of stress fiber assembly(GO:0051497)
0.1 0.3 GO:0050847 progesterone receptor signaling pathway(GO:0050847)
0.1 0.2 GO:0097300 necroptotic process(GO:0070266) programmed necrotic cell death(GO:0097300)
0.1 0.3 GO:0070670 response to interleukin-4(GO:0070670)
0.0 0.1 GO:0032506 cytokinetic process(GO:0032506)
0.0 0.0 GO:0033689 negative regulation of osteoblast proliferation(GO:0033689)
0.0 0.2 GO:0071480 cellular response to gamma radiation(GO:0071480)
0.0 0.1 GO:0052257 pathogen-associated molecular pattern dependent induction by symbiont of host innate immune response(GO:0052033) positive regulation by symbiont of host innate immune response(GO:0052166) modulation by symbiont of host innate immune response(GO:0052167) pathogen-associated molecular pattern dependent modulation by symbiont of host innate immune response(GO:0052169) pathogen-associated molecular pattern dependent induction by organism of innate immune response of other organism involved in symbiotic interaction(GO:0052257) positive regulation by organism of innate immune response in other organism involved in symbiotic interaction(GO:0052305) modulation by organism of innate immune response in other organism involved in symbiotic interaction(GO:0052306) pathogen-associated molecular pattern dependent modulation by organism of innate immune response in other organism involved in symbiotic interaction(GO:0052308)
0.0 0.1 GO:0045046 protein import into peroxisome membrane(GO:0045046)
0.0 0.0 GO:0060028 convergent extension involved in axis elongation(GO:0060028)
0.0 0.1 GO:0034392 negative regulation of smooth muscle cell apoptotic process(GO:0034392)
0.0 0.2 GO:0060159 regulation of dopamine receptor signaling pathway(GO:0060159)
0.0 0.1 GO:0032232 negative regulation of actin filament bundle assembly(GO:0032232)
0.0 0.1 GO:0034219 carbohydrate transmembrane transport(GO:0034219)
0.0 0.1 GO:0051573 negative regulation of histone H3-K9 methylation(GO:0051573)
0.0 0.1 GO:0045343 MHC class I biosynthetic process(GO:0045341) regulation of MHC class I biosynthetic process(GO:0045343)
0.0 0.1 GO:0070682 proteasome regulatory particle assembly(GO:0070682)
0.0 0.1 GO:0071379 cellular response to prostaglandin stimulus(GO:0071379)
0.0 0.3 GO:0048535 lymph node development(GO:0048535)
0.0 0.2 GO:0010508 positive regulation of autophagy(GO:0010508)
0.0 0.1 GO:0017014 protein nitrosylation(GO:0017014) peptidyl-cysteine S-nitrosylation(GO:0018119)
0.0 0.1 GO:0046666 retinal cell programmed cell death(GO:0046666)
0.0 0.1 GO:0060242 contact inhibition(GO:0060242)
0.0 0.5 GO:0000305 response to oxygen radical(GO:0000305)
0.0 0.6 GO:0010389 regulation of G2/M transition of mitotic cell cycle(GO:0010389) regulation of cell cycle G2/M phase transition(GO:1902749)
0.0 0.0 GO:0032715 negative regulation of interleukin-6 production(GO:0032715)
0.0 0.1 GO:0006346 methylation-dependent chromatin silencing(GO:0006346)
0.0 0.1 GO:0009313 oligosaccharide catabolic process(GO:0009313)
0.0 0.2 GO:0010867 positive regulation of triglyceride biosynthetic process(GO:0010867)
0.0 0.1 GO:0002507 tolerance induction(GO:0002507)
0.0 0.1 GO:0070777 D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
0.0 0.3 GO:2001021 negative regulation of response to DNA damage stimulus(GO:2001021)
0.0 0.1 GO:0010447 response to acidic pH(GO:0010447)
0.0 0.1 GO:0018094 protein polyglycylation(GO:0018094)
0.0 0.2 GO:0042535 positive regulation of tumor necrosis factor biosynthetic process(GO:0042535)
0.0 0.1 GO:0002248 connective tissue replacement involved in inflammatory response wound healing(GO:0002248) connective tissue replacement(GO:0097709)
0.0 0.2 GO:0045898 regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045898)
0.0 0.2 GO:0034755 iron ion transmembrane transport(GO:0034755)
0.0 0.0 GO:0003402 planar cell polarity pathway involved in axis elongation(GO:0003402)
0.0 0.0 GO:0071481 cellular response to X-ray(GO:0071481)
0.0 0.1 GO:0045603 positive regulation of endothelial cell differentiation(GO:0045603)
0.0 0.0 GO:0002407 dendritic cell chemotaxis(GO:0002407) dendritic cell migration(GO:0036336)
0.0 0.1 GO:0010216 maintenance of DNA methylation(GO:0010216)
0.0 0.3 GO:0006030 chitin metabolic process(GO:0006030) chitin catabolic process(GO:0006032)
0.0 0.2 GO:0043984 histone H4-K16 acetylation(GO:0043984)
0.0 0.1 GO:0051533 positive regulation of NFAT protein import into nucleus(GO:0051533)
0.0 0.1 GO:0060972 left/right pattern formation(GO:0060972)
0.0 0.1 GO:0070265 necrotic cell death(GO:0070265)
0.0 0.1 GO:0071364 cellular response to epidermal growth factor stimulus(GO:0071364)
0.0 0.1 GO:0060049 regulation of protein glycosylation(GO:0060049)
0.0 0.2 GO:0048520 positive regulation of behavior(GO:0048520)
0.0 0.1 GO:0042339 keratan sulfate metabolic process(GO:0042339)
0.0 0.1 GO:0035025 positive regulation of Rho protein signal transduction(GO:0035025)
0.0 0.1 GO:0046476 glycosylceramide biosynthetic process(GO:0046476)
0.0 0.1 GO:0021780 spinal cord oligodendrocyte cell differentiation(GO:0021529) spinal cord oligodendrocyte cell fate specification(GO:0021530) oligodendrocyte cell fate specification(GO:0021778) glial cell fate specification(GO:0021780)
0.0 0.0 GO:0071801 regulation of podosome assembly(GO:0071801) positive regulation of podosome assembly(GO:0071803)
0.0 0.1 GO:0046101 hypoxanthine biosynthetic process(GO:0046101)
0.0 0.1 GO:0003056 regulation of vascular smooth muscle contraction(GO:0003056)
0.0 0.1 GO:0021932 hindbrain radial glia guided cell migration(GO:0021932)
0.0 0.1 GO:0032212 positive regulation of telomere maintenance via telomerase(GO:0032212) positive regulation of telomere maintenance via telomere lengthening(GO:1904358)
0.0 0.0 GO:0030812 negative regulation of nucleotide catabolic process(GO:0030812)
0.0 0.1 GO:0034626 fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.0 0.0 GO:0034143 negative regulation of toll-like receptor signaling pathway(GO:0034122) regulation of toll-like receptor 4 signaling pathway(GO:0034143)
0.0 0.0 GO:0072179 nephric duct formation(GO:0072179)
0.0 0.1 GO:0048003 antigen processing and presentation of lipid antigen via MHC class Ib(GO:0048003)
0.0 0.1 GO:0070493 thrombin receptor signaling pathway(GO:0070493)
0.0 0.1 GO:0051182 coenzyme transport(GO:0051182)
0.0 0.1 GO:0060394 negative regulation of pathway-restricted SMAD protein phosphorylation(GO:0060394)
0.0 0.1 GO:0051103 DNA ligation involved in DNA repair(GO:0051103)
0.0 0.5 GO:0016578 histone deubiquitination(GO:0016578)
0.0 0.1 GO:0006530 asparagine catabolic process(GO:0006530) asparagine catabolic process via L-aspartate(GO:0033345)
0.0 0.1 GO:0017183 peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183)
0.0 0.1 GO:0006772 thiamine metabolic process(GO:0006772)
0.0 0.1 GO:0032878 regulation of establishment or maintenance of cell polarity(GO:0032878)
0.0 0.1 GO:0010533 regulation of activation of Janus kinase activity(GO:0010533) positive regulation of activation of Janus kinase activity(GO:0010536)
0.0 0.1 GO:0046015 carbon catabolite regulation of transcription(GO:0045990) regulation of transcription by glucose(GO:0046015)
0.0 0.1 GO:0034145 positive regulation of toll-like receptor 4 signaling pathway(GO:0034145)
0.0 0.0 GO:0060426 lung vasculature development(GO:0060426)
0.0 0.0 GO:0017085 response to insecticide(GO:0017085)
0.0 0.2 GO:0008356 asymmetric cell division(GO:0008356)
0.0 0.3 GO:0043508 negative regulation of JUN kinase activity(GO:0043508)
0.0 0.1 GO:0008298 intracellular mRNA localization(GO:0008298)
0.0 0.3 GO:0006379 mRNA cleavage(GO:0006379)
0.0 0.1 GO:0070837 dehydroascorbic acid transport(GO:0070837)
0.0 0.0 GO:0001779 natural killer cell differentiation(GO:0001779)
0.0 0.1 GO:0071360 cellular response to exogenous dsRNA(GO:0071360)
0.0 0.1 GO:0010903 negative regulation of very-low-density lipoprotein particle remodeling(GO:0010903)
0.0 0.1 GO:0060528 secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development(GO:0060528)
0.0 0.1 GO:0010815 bradykinin catabolic process(GO:0010815)
0.0 0.1 GO:0043951 negative regulation of cAMP-mediated signaling(GO:0043951)
0.0 0.2 GO:0010758 regulation of macrophage chemotaxis(GO:0010758)
0.0 0.3 GO:0000381 regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.0 0.0 GO:0010831 positive regulation of myotube differentiation(GO:0010831)
0.0 0.0 GO:0002360 T cell lineage commitment(GO:0002360)
0.0 0.1 GO:0070672 response to interleukin-15(GO:0070672)
0.0 0.1 GO:0048478 replication fork protection(GO:0048478)
0.0 0.1 GO:0006422 aspartyl-tRNA aminoacylation(GO:0006422)
0.0 0.1 GO:0090023 positive regulation of neutrophil chemotaxis(GO:0090023) positive regulation of neutrophil migration(GO:1902624)
0.0 0.1 GO:0033152 immunoglobulin V(D)J recombination(GO:0033152)
0.0 0.1 GO:0032486 Rap protein signal transduction(GO:0032486)
0.0 0.0 GO:0046642 negative regulation of alpha-beta T cell proliferation(GO:0046642)
0.0 1.7 GO:0050852 T cell receptor signaling pathway(GO:0050852)
0.0 0.1 GO:0060287 epithelial cilium movement(GO:0003351) epithelial cilium movement involved in determination of left/right asymmetry(GO:0060287)
0.0 0.1 GO:0045416 positive regulation of interleukin-8 biosynthetic process(GO:0045416)
0.0 0.2 GO:0016556 mRNA modification(GO:0016556)
0.0 0.2 GO:0006553 lysine metabolic process(GO:0006553) lysine catabolic process(GO:0006554)
0.0 0.1 GO:0060123 regulation of growth hormone secretion(GO:0060123)
0.0 0.1 GO:0002281 macrophage activation involved in immune response(GO:0002281)
0.0 0.1 GO:0009134 nucleoside diphosphate catabolic process(GO:0009134) ribonucleoside diphosphate catabolic process(GO:0009191)
0.0 0.1 GO:0019228 neuronal action potential(GO:0019228)
0.0 0.2 GO:0005513 detection of calcium ion(GO:0005513)
0.0 0.1 GO:0021800 cerebral cortex tangential migration(GO:0021800)
0.0 0.0 GO:0001302 replicative cell aging(GO:0001302)
0.0 0.1 GO:0071371 cellular response to gonadotropin stimulus(GO:0071371)
0.0 0.1 GO:0018106 peptidyl-histidine phosphorylation(GO:0018106)
0.0 0.0 GO:0046121 deoxyribonucleoside catabolic process(GO:0046121)
0.0 0.1 GO:0034616 response to laminar fluid shear stress(GO:0034616)
0.0 0.1 GO:0060218 hematopoietic stem cell differentiation(GO:0060218)
0.0 0.1 GO:0034638 phosphatidylcholine catabolic process(GO:0034638)
0.0 0.1 GO:0016264 gap junction assembly(GO:0016264)
0.0 0.1 GO:0006685 sphingomyelin catabolic process(GO:0006685)
0.0 0.0 GO:0001672 regulation of chromatin assembly or disassembly(GO:0001672)
0.0 0.2 GO:0007035 vacuolar acidification(GO:0007035)
0.0 0.0 GO:0006154 adenosine catabolic process(GO:0006154)
0.0 0.1 GO:0090267 positive regulation of spindle checkpoint(GO:0090232) regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090266) positive regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090267) positive regulation of cell cycle checkpoint(GO:1901978) regulation of mitotic spindle checkpoint(GO:1903504)
0.0 0.1 GO:0050869 negative regulation of B cell activation(GO:0050869)
0.0 0.1 GO:0014055 acetylcholine secretion, neurotransmission(GO:0014055) regulation of acetylcholine secretion, neurotransmission(GO:0014056) acetylcholine secretion(GO:0061526)
0.0 0.1 GO:0032814 regulation of natural killer cell activation(GO:0032814)
0.0 0.0 GO:0043117 positive regulation of vascular permeability(GO:0043117)
0.0 0.0 GO:0010592 positive regulation of lamellipodium assembly(GO:0010592) positive regulation of lamellipodium organization(GO:1902745)
0.0 0.1 GO:0006659 phosphatidylserine biosynthetic process(GO:0006659)
0.0 0.1 GO:0090224 regulation of spindle organization(GO:0090224)
0.0 0.1 GO:0051305 chromosome movement towards spindle pole(GO:0051305)
0.0 0.1 GO:0070172 positive regulation of tooth mineralization(GO:0070172)
0.0 0.0 GO:0045414 regulation of interleukin-8 biosynthetic process(GO:0045414)
0.0 0.1 GO:0045910 negative regulation of DNA recombination(GO:0045910)
0.0 0.1 GO:0042117 monocyte activation(GO:0042117)
0.0 0.1 GO:0043461 proton-transporting ATP synthase complex assembly(GO:0043461) proton-transporting ATP synthase complex biogenesis(GO:0070272)
0.0 0.1 GO:0032075 positive regulation of nuclease activity(GO:0032075)
0.0 0.1 GO:0035024 negative regulation of Rho protein signal transduction(GO:0035024)
0.0 0.0 GO:0070932 histone H3 deacetylation(GO:0070932) histone H4 deacetylation(GO:0070933)
0.0 0.0 GO:0060061 Spemann organizer formation(GO:0060061)
0.0 0.5 GO:1901185 negative regulation of epidermal growth factor receptor signaling pathway(GO:0042059) negative regulation of ERBB signaling pathway(GO:1901185)
0.0 0.1 GO:0045091 regulation of single stranded viral RNA replication via double stranded DNA intermediate(GO:0045091)
0.0 0.1 GO:0048711 positive regulation of astrocyte differentiation(GO:0048711)
0.0 0.1 GO:0001675 acrosome assembly(GO:0001675)
0.0 0.0 GO:0072385 minus-end-directed organelle transport along microtubule(GO:0072385)
0.0 0.1 GO:0010739 positive regulation of protein kinase A signaling(GO:0010739)
0.0 0.1 GO:0032119 sequestering of zinc ion(GO:0032119)
0.0 0.2 GO:0042347 negative regulation of NF-kappaB import into nucleus(GO:0042347)
0.0 0.1 GO:0046477 glycosylceramide catabolic process(GO:0046477)
0.0 0.0 GO:0031427 response to methotrexate(GO:0031427)
0.0 0.1 GO:0034063 stress granule assembly(GO:0034063)
0.0 0.0 GO:0046006 regulation of activated T cell proliferation(GO:0046006)
0.0 0.2 GO:0050930 induction of positive chemotaxis(GO:0050930)
0.0 0.1 GO:0003310 pancreatic A cell differentiation(GO:0003310)
0.0 0.1 GO:0070498 interleukin-1-mediated signaling pathway(GO:0070498)
0.0 0.1 GO:0007021 tubulin complex assembly(GO:0007021)
0.0 0.1 GO:0030505 inorganic diphosphate transport(GO:0030505)
0.0 0.1 GO:0034260 negative regulation of GTPase activity(GO:0034260)
0.0 0.1 GO:0000380 alternative mRNA splicing, via spliceosome(GO:0000380)
0.0 0.1 GO:0035308 negative regulation of dephosphorylation(GO:0035305) negative regulation of protein dephosphorylation(GO:0035308)
0.0 0.1 GO:0036465 synaptic vesicle recycling(GO:0036465) synaptic vesicle endocytosis(GO:0048488) clathrin-mediated endocytosis(GO:0072583)
0.0 0.1 GO:0043330 response to exogenous dsRNA(GO:0043330)
0.0 0.2 GO:0043124 negative regulation of I-kappaB kinase/NF-kappaB signaling(GO:0043124)
0.0 0.1 GO:0006857 oligopeptide transport(GO:0006857)
0.0 0.0 GO:0071883 adrenergic receptor signaling pathway(GO:0071875) activation of MAPK activity by adrenergic receptor signaling pathway(GO:0071883)
0.0 0.0 GO:0032682 negative regulation of chemokine production(GO:0032682) negative regulation of chemokine biosynthetic process(GO:0045079)
0.0 0.1 GO:0061099 negative regulation of protein tyrosine kinase activity(GO:0061099)
0.0 0.1 GO:0061365 positive regulation of lipoprotein lipase activity(GO:0051006) positive regulation of triglyceride lipase activity(GO:0061365)
0.0 0.0 GO:0048670 regulation of collateral sprouting(GO:0048670)
0.0 0.2 GO:0007628 adult walking behavior(GO:0007628) walking behavior(GO:0090659)
0.0 0.0 GO:0007132 meiotic metaphase I(GO:0007132)
0.0 0.1 GO:0015840 urea transport(GO:0015840)
0.0 0.1 GO:0033631 cell-cell adhesion mediated by integrin(GO:0033631)
0.0 0.1 GO:0009051 pentose-phosphate shunt, oxidative branch(GO:0009051)
0.0 0.1 GO:0006089 lactate metabolic process(GO:0006089)
0.0 0.1 GO:0017121 phospholipid scrambling(GO:0017121)
0.0 0.1 GO:0032875 regulation of DNA endoreduplication(GO:0032875) negative regulation of DNA endoreduplication(GO:0032876) DNA endoreduplication(GO:0042023)
0.0 0.1 GO:0003084 positive regulation of systemic arterial blood pressure(GO:0003084)
0.0 0.1 GO:0033169 histone H3-K9 demethylation(GO:0033169)
0.0 0.1 GO:0022614 membrane to membrane docking(GO:0022614)
0.0 0.1 GO:0045672 positive regulation of osteoclast differentiation(GO:0045672)
0.0 0.0 GO:0035413 positive regulation of catenin import into nucleus(GO:0035413)
0.0 0.0 GO:0002523 leukocyte migration involved in inflammatory response(GO:0002523)
0.0 0.0 GO:0050435 beta-amyloid metabolic process(GO:0050435)
0.0 0.1 GO:0032926 negative regulation of activin receptor signaling pathway(GO:0032926)
0.0 0.0 GO:0009143 nucleoside triphosphate catabolic process(GO:0009143)
0.0 0.0 GO:0018125 peptidyl-cysteine methylation(GO:0018125)
0.0 0.1 GO:0006011 UDP-glucose metabolic process(GO:0006011)
0.0 0.0 GO:0031645 negative regulation of neurological system process(GO:0031645)
0.0 0.0 GO:0034983 peptidyl-lysine deacetylation(GO:0034983)
0.0 0.1 GO:0000183 chromatin silencing at rDNA(GO:0000183)
0.0 0.1 GO:0042487 regulation of odontogenesis of dentin-containing tooth(GO:0042487)
0.0 0.1 GO:0015671 oxygen transport(GO:0015671)
0.0 0.0 GO:0043568 positive regulation of insulin-like growth factor receptor signaling pathway(GO:0043568)
0.0 0.1 GO:0042416 dopamine biosynthetic process(GO:0042416)
0.0 0.1 GO:0016572 histone phosphorylation(GO:0016572)
0.0 0.1 GO:0046940 nucleoside monophosphate phosphorylation(GO:0046940)
0.0 0.1 GO:0034370 triglyceride-rich lipoprotein particle remodeling(GO:0034370) very-low-density lipoprotein particle remodeling(GO:0034372)
0.0 0.1 GO:0000019 regulation of mitotic recombination(GO:0000019)
0.0 0.0 GO:0033688 regulation of osteoblast proliferation(GO:0033688)
0.0 0.1 GO:0045292 mRNA cis splicing, via spliceosome(GO:0045292)
0.0 0.0 GO:1902101 positive regulation of mitotic metaphase/anaphase transition(GO:0045842) positive regulation of mitotic sister chromatid separation(GO:1901970) positive regulation of metaphase/anaphase transition of cell cycle(GO:1902101)
0.0 0.0 GO:0046100 hypoxanthine metabolic process(GO:0046100)
0.0 0.0 GO:0033173 calcineurin-NFAT signaling cascade(GO:0033173)
0.0 0.0 GO:0045541 negative regulation of cholesterol biosynthetic process(GO:0045541) negative regulation of cholesterol metabolic process(GO:0090206)
0.0 0.0 GO:0060129 thyroid-stimulating hormone-secreting cell differentiation(GO:0060129)
0.0 0.0 GO:0048289 isotype switching to IgE isotypes(GO:0048289) regulation of isotype switching to IgE isotypes(GO:0048293)
0.0 0.1 GO:0046831 regulation of RNA export from nucleus(GO:0046831)
0.0 0.2 GO:0045648 positive regulation of erythrocyte differentiation(GO:0045648)
0.0 0.0 GO:0070602 centromeric sister chromatid cohesion(GO:0070601) regulation of centromeric sister chromatid cohesion(GO:0070602)
0.0 0.0 GO:0061687 detoxification of inorganic compound(GO:0061687) stress response to metal ion(GO:0097501)
0.0 0.0 GO:0051973 positive regulation of telomerase activity(GO:0051973)
0.0 0.0 GO:0001787 natural killer cell proliferation(GO:0001787)
0.0 0.0 GO:0051970 negative regulation of transmission of nerve impulse(GO:0051970)
0.0 0.1 GO:0009649 entrainment of circadian clock(GO:0009649)
0.0 0.7 GO:0060333 interferon-gamma-mediated signaling pathway(GO:0060333)
0.0 0.5 GO:0050772 positive regulation of axonogenesis(GO:0050772)
0.0 0.0 GO:0008049 male courtship behavior(GO:0008049)
0.0 0.0 GO:0042670 retinal cone cell differentiation(GO:0042670) retinal cone cell development(GO:0046549)
0.0 0.1 GO:0006477 protein sulfation(GO:0006477)
0.0 0.2 GO:0042776 mitochondrial ATP synthesis coupled proton transport(GO:0042776)
0.0 0.1 GO:0030206 chondroitin sulfate biosynthetic process(GO:0030206)
0.0 0.1 GO:0006102 isocitrate metabolic process(GO:0006102)
0.0 0.2 GO:0042771 intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator(GO:0042771)
0.0 0.1 GO:0043631 RNA polyadenylation(GO:0043631)
0.0 0.0 GO:0019532 oxalate transport(GO:0019532)
0.0 0.0 GO:0071392 cellular response to estradiol stimulus(GO:0071392)
0.0 0.1 GO:0015712 hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760)
0.0 0.0 GO:0007352 zygotic specification of dorsal/ventral axis(GO:0007352)
0.0 0.0 GO:0010832 negative regulation of myotube differentiation(GO:0010832)
0.0 0.0 GO:0006167 AMP biosynthetic process(GO:0006167)
0.0 0.1 GO:0045022 early endosome to late endosome transport(GO:0045022) vesicle-mediated transport between endosomal compartments(GO:0098927)
0.0 0.0 GO:1901374 acetylcholine transport(GO:0015870) acetate ester transport(GO:1901374)
0.0 0.1 GO:1902603 carnitine shuttle(GO:0006853) carnitine transmembrane transport(GO:1902603)
0.0 0.0 GO:0034067 protein localization to Golgi apparatus(GO:0034067)
0.0 0.3 GO:0007602 phototransduction(GO:0007602)
0.0 0.1 GO:0008105 asymmetric protein localization(GO:0008105)
0.0 0.0 GO:2000171 negative regulation of dendrite development(GO:2000171)
0.0 0.1 GO:0048024 regulation of mRNA splicing, via spliceosome(GO:0048024)
0.0 0.1 GO:0032981 NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.0 0.0 GO:0040009 regulation of growth rate(GO:0040009)
0.0 0.0 GO:1903672 regulation of cell migration involved in sprouting angiogenesis(GO:0090049) positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050) regulation of sprouting angiogenesis(GO:1903670) positive regulation of sprouting angiogenesis(GO:1903672)
0.0 0.1 GO:0010042 response to manganese ion(GO:0010042)
0.0 0.4 GO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:0000184)
0.0 0.1 GO:0098657 neurotransmitter uptake(GO:0001504) import into cell(GO:0098657)
0.0 0.1 GO:0000244 spliceosomal tri-snRNP complex assembly(GO:0000244)
0.0 0.0 GO:0045835 negative regulation of meiotic nuclear division(GO:0045835)
0.0 0.2 GO:0033209 tumor necrosis factor-mediated signaling pathway(GO:0033209)
0.0 0.2 GO:0016254 preassembly of GPI anchor in ER membrane(GO:0016254)
0.0 0.0 GO:0032925 regulation of activin receptor signaling pathway(GO:0032925)
0.0 0.2 GO:0007076 mitotic chromosome condensation(GO:0007076)
0.0 0.0 GO:0015705 iodide transport(GO:0015705)
0.0 0.1 GO:0032109 positive regulation of response to extracellular stimulus(GO:0032106) positive regulation of response to nutrient levels(GO:0032109)
0.0 0.7 GO:0008360 regulation of cell shape(GO:0008360)
0.0 0.0 GO:0031935 regulation of chromatin silencing(GO:0031935)
0.0 0.0 GO:0051988 regulation of attachment of spindle microtubules to kinetochore(GO:0051988)
0.0 0.1 GO:0006704 glucocorticoid biosynthetic process(GO:0006704)
0.0 0.0 GO:0045070 positive regulation of viral genome replication(GO:0045070)
0.0 0.2 GO:0048814 regulation of dendrite morphogenesis(GO:0048814)
0.0 0.1 GO:0031103 axon regeneration(GO:0031103)
0.0 0.1 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.0 0.0 GO:0034698 response to gonadotropin(GO:0034698)
0.0 0.0 GO:0033033 negative regulation of myeloid cell apoptotic process(GO:0033033)
0.0 0.1 GO:0006684 sphingomyelin metabolic process(GO:0006684)
0.0 0.0 GO:0021707 cerebellar granular layer development(GO:0021681) cerebellar granular layer morphogenesis(GO:0021683) cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707)
0.0 0.1 GO:0032456 endocytic recycling(GO:0032456)
0.0 0.1 GO:0002921 negative regulation of humoral immune response(GO:0002921) negative regulation of complement activation(GO:0045916) negative regulation of protein activation cascade(GO:2000258)
0.0 0.1 GO:0048016 inositol phosphate-mediated signaling(GO:0048016)
0.0 0.1 GO:0050908 detection of light stimulus involved in visual perception(GO:0050908) detection of light stimulus involved in sensory perception(GO:0050962)
0.0 0.2 GO:0034199 activation of protein kinase A activity(GO:0034199)
0.0 0.0 GO:0031573 intra-S DNA damage checkpoint(GO:0031573)
0.0 0.0 GO:0042921 glucocorticoid receptor signaling pathway(GO:0042921)
0.0 0.0 GO:0050765 negative regulation of phagocytosis(GO:0050765)
0.0 0.1 GO:0045814 negative regulation of gene expression, epigenetic(GO:0045814)
0.0 0.0 GO:0043320 natural killer cell activation involved in immune response(GO:0002323) natural killer cell degranulation(GO:0043320)
0.0 0.1 GO:0046519 sphingoid metabolic process(GO:0046519)
0.0 0.0 GO:0015791 polyol transport(GO:0015791)
0.0 0.0 GO:0006978 DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:0006978)
0.0 0.1 GO:0031115 negative regulation of microtubule polymerization(GO:0031115)
0.0 0.1 GO:0001510 RNA methylation(GO:0001510)
0.0 0.0 GO:0031223 auditory behavior(GO:0031223)
0.0 0.1 GO:0071482 cellular response to light stimulus(GO:0071482)
0.0 0.0 GO:0071922 establishment of sister chromatid cohesion(GO:0034085) cohesin loading(GO:0071921) regulation of cohesin loading(GO:0071922)
0.0 0.1 GO:0043628 ncRNA 3'-end processing(GO:0043628)
0.0 0.2 GO:0051607 defense response to virus(GO:0051607)
0.0 0.3 GO:0030199 collagen fibril organization(GO:0030199)
0.0 0.0 GO:0000470 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000463) maturation of LSU-rRNA(GO:0000470)
0.0 0.0 GO:0046501 protoporphyrinogen IX metabolic process(GO:0046501)
0.0 0.0 GO:0072526 pyridine-containing compound catabolic process(GO:0072526)
0.0 0.0 GO:0033522 histone H2A ubiquitination(GO:0033522)
0.0 0.2 GO:0000289 nuclear-transcribed mRNA poly(A) tail shortening(GO:0000289)
0.0 0.1 GO:0031648 protein destabilization(GO:0031648)
0.0 0.0 GO:0052200 response to defenses of other organism involved in symbiotic interaction(GO:0052173) response to host defenses(GO:0052200) response to host(GO:0075136)
0.0 0.0 GO:0050917 sensory perception of umami taste(GO:0050917)
0.0 0.0 GO:0071294 cellular response to zinc ion(GO:0071294)
0.0 0.1 GO:0008343 adult feeding behavior(GO:0008343)
0.0 0.2 GO:0030317 sperm motility(GO:0030317)
0.0 0.0 GO:0071569 protein ufmylation(GO:0071569)
0.0 0.0 GO:0048388 endosomal lumen acidification(GO:0048388)
0.0 0.1 GO:0030212 hyaluronan metabolic process(GO:0030212)
0.0 0.0 GO:0031498 nucleosome disassembly(GO:0006337) chromatin disassembly(GO:0031498) protein-DNA complex disassembly(GO:0032986)
0.0 0.2 GO:0006904 vesicle docking involved in exocytosis(GO:0006904)
0.0 0.1 GO:0048387 negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.0 0.0 GO:0021612 cranial nerve structural organization(GO:0021604) facial nerve morphogenesis(GO:0021610) facial nerve structural organization(GO:0021612) anatomical structure arrangement(GO:0048532)
0.0 0.0 GO:0048710 regulation of astrocyte differentiation(GO:0048710)
0.0 0.1 GO:0006020 inositol metabolic process(GO:0006020)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.5 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)
0.1 0.4 GO:0030934 anchoring collagen complex(GO:0030934)
0.1 0.3 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.1 0.7 GO:0001891 phagocytic cup(GO:0001891)
0.1 0.3 GO:0005900 oncostatin-M receptor complex(GO:0005900)
0.1 0.3 GO:0034992 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.1 0.3 GO:0005954 calcium- and calmodulin-dependent protein kinase complex(GO:0005954)
0.1 0.3 GO:0005827 polar microtubule(GO:0005827)
0.1 0.2 GO:0072487 MSL complex(GO:0072487)
0.1 0.2 GO:0033270 paranode region of axon(GO:0033270)
0.1 0.2 GO:0032009 early phagosome(GO:0032009)
0.1 0.2 GO:0000137 Golgi cis cisterna(GO:0000137)
0.1 0.2 GO:0042629 mast cell granule(GO:0042629)
0.1 0.2 GO:0031932 TORC2 complex(GO:0031932)
0.0 0.3 GO:0072357 PTW/PP1 phosphatase complex(GO:0072357)
0.0 0.5 GO:0001772 immunological synapse(GO:0001772)
0.0 0.5 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.0 0.5 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.0 0.1 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.0 0.5 GO:0045334 clathrin-coated endocytic vesicle(GO:0045334)
0.0 0.2 GO:0044224 juxtaparanode region of axon(GO:0044224)
0.0 0.1 GO:0038201 TOR complex(GO:0038201)
0.0 0.2 GO:0000125 PCAF complex(GO:0000125)
0.0 0.3 GO:0031105 septin complex(GO:0031105) septin cytoskeleton(GO:0032156)
0.0 0.2 GO:0019907 cyclin-dependent protein kinase activating kinase holoenzyme complex(GO:0019907)
0.0 0.2 GO:0005697 telomerase holoenzyme complex(GO:0005697)
0.0 0.1 GO:0072669 tRNA-splicing ligase complex(GO:0072669)
0.0 0.1 GO:0008540 proteasome regulatory particle, base subcomplex(GO:0008540)
0.0 0.2 GO:0042598 obsolete vesicular fraction(GO:0042598)
0.0 0.3 GO:0005849 mRNA cleavage factor complex(GO:0005849)
0.0 0.1 GO:0005862 muscle thin filament tropomyosin(GO:0005862)
0.0 0.2 GO:0008290 F-actin capping protein complex(GO:0008290)
0.0 0.1 GO:0070062 extracellular exosome(GO:0070062) extracellular vesicle(GO:1903561)
0.0 0.0 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.0 0.1 GO:0005899 insulin receptor complex(GO:0005899)
0.0 0.1 GO:0000300 obsolete peripheral to membrane of membrane fraction(GO:0000300)
0.0 0.1 GO:0070695 FHF complex(GO:0070695)
0.0 1.0 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.0 0.1 GO:0071438 invadopodium membrane(GO:0071438)
0.0 0.0 GO:0071437 invadopodium(GO:0071437)
0.0 0.1 GO:0034673 inhibin-betaglycan-ActRII complex(GO:0034673)
0.0 0.1 GO:0043218 compact myelin(GO:0043218)
0.0 0.1 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.0 0.4 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.0 0.1 GO:0019908 nuclear cyclin-dependent protein kinase holoenzyme complex(GO:0019908)
0.0 0.1 GO:0032591 dendritic spine membrane(GO:0032591)
0.0 0.1 GO:0031371 ubiquitin conjugating enzyme complex(GO:0031371)
0.0 0.1 GO:0070775 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.0 0.1 GO:0033150 cytoskeletal calyx(GO:0033150)
0.0 0.2 GO:0045120 pronucleus(GO:0045120)
0.0 0.0 GO:0032593 insulin-responsive compartment(GO:0032593)
0.0 0.1 GO:0031254 uropod(GO:0001931) cell trailing edge(GO:0031254)
0.0 0.2 GO:0032839 dendrite cytoplasm(GO:0032839)
0.0 0.1 GO:0035189 Rb-E2F complex(GO:0035189)
0.0 0.1 GO:0005826 actomyosin contractile ring(GO:0005826)
0.0 0.1 GO:0033162 melanosome membrane(GO:0033162) chitosome(GO:0045009)
0.0 0.1 GO:0001652 granular component(GO:0001652)
0.0 0.1 GO:0031616 spindle pole centrosome(GO:0031616)
0.0 0.0 GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.0 0.4 GO:0005626 obsolete insoluble fraction(GO:0005626)
0.0 0.1 GO:0071204 histone pre-mRNA 3'end processing complex(GO:0071204)
0.0 0.1 GO:0030904 retromer complex(GO:0030904)
0.0 0.4 GO:0032587 ruffle membrane(GO:0032587)
0.0 0.1 GO:0043190 ATP-binding cassette (ABC) transporter complex(GO:0043190)
0.0 0.0 GO:0032449 CBM complex(GO:0032449)
0.0 0.0 GO:0005588 collagen type V trimer(GO:0005588)
0.0 0.3 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 0.1 GO:0070552 BRISC complex(GO:0070552)
0.0 0.1 GO:0033276 transcription factor TFTC complex(GO:0033276)
0.0 0.1 GO:0016342 catenin complex(GO:0016342)
0.0 0.3 GO:0034385 very-low-density lipoprotein particle(GO:0034361) triglyceride-rich lipoprotein particle(GO:0034385)
0.0 0.1 GO:0042788 polysomal ribosome(GO:0042788)
0.0 0.4 GO:0030175 filopodium(GO:0030175)
0.0 0.1 GO:0031265 CD95 death-inducing signaling complex(GO:0031265)
0.0 0.1 GO:0000275 mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275)
0.0 0.1 GO:0005797 Golgi medial cisterna(GO:0005797)
0.0 0.0 GO:0033011 perinuclear theca(GO:0033011)
0.0 0.0 GO:0033268 node of Ranvier(GO:0033268)
0.0 0.0 GO:0005927 muscle tendon junction(GO:0005927)
0.0 0.1 GO:0031010 ISWI-type complex(GO:0031010)
0.0 0.1 GO:0000796 condensin complex(GO:0000796)
0.0 0.0 GO:0046540 U4/U6 x U5 tri-snRNP complex(GO:0046540) spliceosomal tri-snRNP complex(GO:0097526)
0.0 0.0 GO:0070545 PeBoW complex(GO:0070545)
0.0 0.6 GO:0031901 early endosome membrane(GO:0031901)
0.0 0.0 GO:0071942 XPC complex(GO:0071942)
0.0 0.2 GO:0098573 intrinsic component of mitochondrial membrane(GO:0098573)
0.0 0.1 GO:0030673 axolemma(GO:0030673)
0.0 0.2 GO:0030530 obsolete heterogeneous nuclear ribonucleoprotein complex(GO:0030530)
0.0 0.1 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.0 0.0 GO:0030895 apolipoprotein B mRNA editing enzyme complex(GO:0030895)
0.0 0.0 GO:0005594 collagen type IX trimer(GO:0005594)
0.0 0.1 GO:0042101 T cell receptor complex(GO:0042101)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.5 GO:0003836 beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.1 0.4 GO:0016309 1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
0.1 0.9 GO:0016494 C-X-C chemokine receptor activity(GO:0016494)
0.1 0.4 GO:0004911 interleukin-2 receptor activity(GO:0004911)
0.1 0.4 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.1 0.3 GO:0031628 opioid receptor binding(GO:0031628)
0.1 1.0 GO:0016493 C-C chemokine receptor activity(GO:0016493)
0.1 0.4 GO:0047238 glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity(GO:0047238)
0.1 0.3 GO:0030368 interleukin-17 receptor activity(GO:0030368)
0.1 0.3 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.1 0.2 GO:0008321 Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.1 0.3 GO:0030284 estrogen receptor activity(GO:0030284)
0.1 0.3 GO:0015925 galactosidase activity(GO:0015925)
0.1 0.2 GO:0035197 siRNA binding(GO:0035197)
0.1 0.1 GO:0000268 peroxisome targeting sequence binding(GO:0000268)
0.1 0.2 GO:0004677 DNA-dependent protein kinase activity(GO:0004677)
0.1 0.2 GO:0033691 sialic acid binding(GO:0033691)
0.1 0.4 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.1 0.4 GO:0030020 extracellular matrix structural constituent conferring tensile strength(GO:0030020)
0.1 0.2 GO:0035184 histone threonine kinase activity(GO:0035184)
0.1 0.2 GO:0004774 succinate-CoA ligase activity(GO:0004774)
0.1 0.2 GO:0008174 mRNA methyltransferase activity(GO:0008174)
0.1 0.2 GO:0015204 urea transmembrane transporter activity(GO:0015204)
0.1 0.2 GO:0030375 thyroid hormone receptor coactivator activity(GO:0030375)
0.1 0.2 GO:0050815 phosphoserine binding(GO:0050815)
0.1 0.2 GO:0004311 farnesyltranstransferase activity(GO:0004311)
0.1 0.2 GO:0008420 CTD phosphatase activity(GO:0008420)
0.1 0.3 GO:0005131 growth hormone receptor binding(GO:0005131)
0.1 0.4 GO:0005522 profilin binding(GO:0005522)
0.0 0.4 GO:0030332 cyclin binding(GO:0030332)
0.0 0.1 GO:0043175 RNA polymerase core enzyme binding(GO:0043175)
0.0 0.6 GO:0005095 GTPase inhibitor activity(GO:0005095)
0.0 0.1 GO:0004591 oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591)
0.0 0.1 GO:0042156 obsolete zinc-mediated transcriptional activator activity(GO:0042156)
0.0 1.7 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.0 0.7 GO:0030159 receptor signaling complex scaffold activity(GO:0030159)
0.0 0.1 GO:0003726 double-stranded RNA adenosine deaminase activity(GO:0003726)
0.0 0.9 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.0 0.2 GO:0001637 G-protein coupled chemoattractant receptor activity(GO:0001637) chemokine receptor activity(GO:0004950)
0.0 0.3 GO:0008440 inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440) inositol trisphosphate kinase activity(GO:0051766)
0.0 0.4 GO:0034593 phosphatidylinositol bisphosphate phosphatase activity(GO:0034593)
0.0 0.5 GO:0004697 protein kinase C activity(GO:0004697)
0.0 0.5 GO:0005031 tumor necrosis factor-activated receptor activity(GO:0005031)
0.0 1.0 GO:0045028 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.0 0.1 GO:0004566 beta-glucuronidase activity(GO:0004566)
0.0 0.2 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.0 0.3 GO:0015271 outward rectifier potassium channel activity(GO:0015271)
0.0 0.1 GO:0070735 protein-glycine ligase activity(GO:0070735)
0.0 0.2 GO:0005381 iron ion transmembrane transporter activity(GO:0005381)
0.0 0.2 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity(GO:0004694)
0.0 0.2 GO:0061630 ubiquitin-ubiquitin ligase activity(GO:0034450) ubiquitin protein ligase activity(GO:0061630) ubiquitin-like protein ligase activity(GO:0061659)
0.0 0.4 GO:0051018 protein kinase A binding(GO:0051018)
0.0 0.1 GO:0003909 DNA ligase activity(GO:0003909) DNA ligase (ATP) activity(GO:0003910)
0.0 0.1 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454)
0.0 0.2 GO:0004706 JUN kinase kinase kinase activity(GO:0004706)
0.0 0.1 GO:0001609 G-protein coupled adenosine receptor activity(GO:0001609)
0.0 0.3 GO:0004568 chitinase activity(GO:0004568)
0.0 0.1 GO:0001591 dopamine neurotransmitter receptor activity, coupled via Gi/Go(GO:0001591)
0.0 0.1 GO:0070097 delta-catenin binding(GO:0070097)
0.0 0.2 GO:0004957 prostaglandin E receptor activity(GO:0004957)
0.0 0.2 GO:0052813 phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) phosphatidylinositol bisphosphate kinase activity(GO:0052813)
0.0 0.1 GO:0005134 interleukin-2 receptor binding(GO:0005134)
0.0 0.3 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.0 0.1 GO:0016842 amidine-lyase activity(GO:0016842)
0.0 0.1 GO:0005350 pyrimidine nucleobase transmembrane transporter activity(GO:0005350)
0.0 0.1 GO:0005113 patched binding(GO:0005113)
0.0 0.2 GO:0016857 racemase and epimerase activity, acting on carbohydrates and derivatives(GO:0016857)
0.0 0.2 GO:0030346 protein phosphatase 2B binding(GO:0030346)
0.0 0.0 GO:0032139 dinucleotide insertion or deletion binding(GO:0032139)
0.0 0.3 GO:0015385 sodium:proton antiporter activity(GO:0015385)
0.0 0.1 GO:0005275 amine transmembrane transporter activity(GO:0005275)
0.0 0.0 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.0 0.1 GO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.0 0.1 GO:0034713 type I transforming growth factor beta receptor binding(GO:0034713)
0.0 0.1 GO:0004167 dopachrome isomerase activity(GO:0004167)
0.0 0.1 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.0 0.1 GO:0004307 ethanolaminephosphotransferase activity(GO:0004307)
0.0 0.1 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
0.0 0.2 GO:0070410 co-SMAD binding(GO:0070410)
0.0 0.1 GO:0033300 dehydroascorbic acid transporter activity(GO:0033300)
0.0 1.4 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.0 0.1 GO:0070653 high-density lipoprotein particle receptor binding(GO:0070653)
0.0 0.1 GO:0003985 acetyl-CoA C-acetyltransferase activity(GO:0003985)
0.0 0.4 GO:0031593 polyubiquitin binding(GO:0031593)
0.0 0.1 GO:0005176 ErbB-2 class receptor binding(GO:0005176)
0.0 0.1 GO:0005521 lamin binding(GO:0005521)
0.0 0.2 GO:0045309 protein phosphorylated amino acid binding(GO:0045309)
0.0 0.1 GO:0003953 NAD+ nucleosidase activity(GO:0003953)
0.0 0.1 GO:0004815 aspartate-tRNA ligase activity(GO:0004815)
0.0 0.2 GO:0003747 translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079)
0.0 0.1 GO:0004563 beta-N-acetylhexosaminidase activity(GO:0004563)
0.0 0.3 GO:0034739 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041) histone deacetylase activity (H4-K16 specific)(GO:0034739) NAD-dependent histone deacetylase activity (H4-K16 specific)(GO:0046970)
0.0 0.1 GO:0046975 histone methyltransferase activity (H3-K36 specific)(GO:0046975)
0.0 0.1 GO:0008607 phosphorylase kinase regulator activity(GO:0008607)
0.0 0.1 GO:0016941 natriuretic peptide receptor activity(GO:0016941)
0.0 0.1 GO:0003829 beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity(GO:0003829)
0.0 0.1 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.0 0.3 GO:0043425 bHLH transcription factor binding(GO:0043425)
0.0 0.0 GO:0015421 oligopeptide-transporting ATPase activity(GO:0015421) peptide-transporting ATPase activity(GO:0015440)
0.0 0.1 GO:0005314 high-affinity glutamate transmembrane transporter activity(GO:0005314)
0.0 0.1 GO:0030881 beta-2-microglobulin binding(GO:0030881)
0.0 0.2 GO:0051879 Hsp90 protein binding(GO:0051879)
0.0 0.1 GO:0015288 porin activity(GO:0015288)
0.0 0.2 GO:0099604 calcium-release channel activity(GO:0015278) ligand-gated calcium channel activity(GO:0099604)
0.0 0.1 GO:0015333 peptide:proton symporter activity(GO:0015333) proton-dependent peptide secondary active transmembrane transporter activity(GO:0022897)
0.0 0.0 GO:0000400 four-way junction DNA binding(GO:0000400)
0.0 0.0 GO:0050698 proteoglycan sulfotransferase activity(GO:0050698)
0.0 0.1 GO:0070215 obsolete MDM2 binding(GO:0070215)
0.0 0.1 GO:0004802 transketolase activity(GO:0004802)
0.0 0.4 GO:0004683 calmodulin-dependent protein kinase activity(GO:0004683)
0.0 0.1 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.0 0.4 GO:0045296 cadherin binding(GO:0045296)
0.0 0.1 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.0 0.2 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.0 0.1 GO:0043141 ATP-dependent 5'-3' DNA helicase activity(GO:0043141)
0.0 0.1 GO:0032794 GTPase activating protein binding(GO:0032794)
0.0 0.5 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.0 0.1 GO:0016748 succinyltransferase activity(GO:0016748)
0.0 0.1 GO:0004000 adenosine deaminase activity(GO:0004000)
0.0 0.1 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.0 0.1 GO:0008296 3'-5'-exodeoxyribonuclease activity(GO:0008296)
0.0 0.1 GO:0043008 ATP-dependent protein binding(GO:0043008)
0.0 0.1 GO:0042043 neurexin family protein binding(GO:0042043)
0.0 0.1 GO:0004596 peptide alpha-N-acetyltransferase activity(GO:0004596)
0.0 0.4 GO:0008484 sulfuric ester hydrolase activity(GO:0008484)
0.0 0.3 GO:0019198 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.0 0.1 GO:0015252 hydrogen ion channel activity(GO:0015252)
0.0 0.1 GO:0047631 ADP-ribose diphosphatase activity(GO:0047631)
0.0 0.1 GO:0097493 extracellular matrix constituent conferring elasticity(GO:0030023) structural molecule activity conferring elasticity(GO:0097493)
0.0 0.1 GO:0034481 chondroitin sulfotransferase activity(GO:0034481)
0.0 0.1 GO:0008494 translation activator activity(GO:0008494)
0.0 0.1 GO:0030292 protein tyrosine kinase inhibitor activity(GO:0030292)
0.0 0.1 GO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.0 0.1 GO:0008649 rRNA methyltransferase activity(GO:0008649)
0.0 0.1 GO:0032137 guanine/thymine mispair binding(GO:0032137)
0.0 0.1 GO:0004449 isocitrate dehydrogenase (NAD+) activity(GO:0004449)
0.0 0.2 GO:0004602 glutathione peroxidase activity(GO:0004602)
0.0 0.1 GO:0055106 ligase regulator activity(GO:0055103) ubiquitin-protein transferase regulator activity(GO:0055106)
0.0 0.1 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.0 0.1 GO:0034187 obsolete apolipoprotein E binding(GO:0034187)
0.0 0.1 GO:0017128 phospholipid scramblase activity(GO:0017128)
0.0 0.1 GO:0004946 bombesin receptor activity(GO:0004946)
0.0 0.1 GO:0004607 phosphatidylcholine-sterol O-acyltransferase activity(GO:0004607)
0.0 0.1 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574) ATP-dependent microtubule motor activity(GO:1990939)
0.0 0.1 GO:0042392 sphingosine-1-phosphate phosphatase activity(GO:0042392)
0.0 0.0 GO:0017162 aryl hydrocarbon receptor binding(GO:0017162)
0.0 0.1 GO:0016922 ligand-dependent nuclear receptor binding(GO:0016922)
0.0 0.1 GO:0008184 glycogen phosphorylase activity(GO:0008184)
0.0 0.1 GO:0043184 vascular endothelial growth factor receptor 2 binding(GO:0043184)
0.0 0.1 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.0 0.1 GO:0016778 diphosphotransferase activity(GO:0016778)
0.0 0.1 GO:0019166 trans-2-enoyl-CoA reductase (NADPH) activity(GO:0019166)
0.0 0.1 GO:0004862 cAMP-dependent protein kinase inhibitor activity(GO:0004862)
0.0 0.2 GO:0042162 telomeric DNA binding(GO:0042162)
0.0 0.1 GO:0036137 kynurenine-oxoglutarate transaminase activity(GO:0016212) kynurenine aminotransferase activity(GO:0036137)
0.0 0.2 GO:0042166 acetylcholine binding(GO:0042166)
0.0 0.1 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.0 0.3 GO:0008601 protein phosphatase type 2A regulator activity(GO:0008601)
0.0 0.5 GO:0003823 antigen binding(GO:0003823)
0.0 0.4 GO:0003746 translation elongation factor activity(GO:0003746)
0.0 0.1 GO:0000064 L-ornithine transmembrane transporter activity(GO:0000064)
0.0 0.1 GO:0004095 carnitine O-palmitoyltransferase activity(GO:0004095) O-palmitoyltransferase activity(GO:0016416)
0.0 0.0 GO:0070548 L-glutamine aminotransferase activity(GO:0070548)
0.0 0.1 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.0 0.0 GO:0031849 olfactory receptor binding(GO:0031849)
0.0 1.0 GO:0004221 obsolete ubiquitin thiolesterase activity(GO:0004221)
0.0 0.1 GO:0016847 1-aminocyclopropane-1-carboxylate synthase activity(GO:0016847)
0.0 0.0 GO:0017159 pantetheine hydrolase activity(GO:0017159)
0.0 0.0 GO:0010861 thyroid hormone receptor activator activity(GO:0010861)
0.0 0.0 GO:0004949 cannabinoid receptor activity(GO:0004949)
0.0 0.0 GO:0030976 thiamine pyrophosphate binding(GO:0030976)
0.0 0.0 GO:0061731 ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
0.0 0.1 GO:0035252 UDP-xylosyltransferase activity(GO:0035252) xylosyltransferase activity(GO:0042285)
0.0 0.0 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.0 0.0 GO:0070492 oligosaccharide binding(GO:0070492)
0.0 0.0 GO:0030229 very-low-density lipoprotein particle receptor activity(GO:0030229)
0.0 0.4 GO:0001104 RNA polymerase II transcription cofactor activity(GO:0001104)
0.0 0.1 GO:0004652 polynucleotide adenylyltransferase activity(GO:0004652)
0.0 0.1 GO:0046974 histone methyltransferase activity (H3-K9 specific)(GO:0046974)
0.0 0.1 GO:0016934 extracellular-glycine-gated ion channel activity(GO:0016933) extracellular-glycine-gated chloride channel activity(GO:0016934)
0.0 0.1 GO:0015057 thrombin receptor activity(GO:0015057)
0.0 0.4 GO:0004402 histone acetyltransferase activity(GO:0004402)
0.0 0.0 GO:0030354 melanin-concentrating hormone activity(GO:0030354)
0.0 0.5 GO:0017048 Rho GTPase binding(GO:0017048)
0.0 0.0 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.0 0.1 GO:0017110 nucleoside-diphosphatase activity(GO:0017110)
0.0 0.1 GO:0047429 nucleoside-triphosphate diphosphatase activity(GO:0047429)
0.0 0.0 GO:0004938 alpha2-adrenergic receptor activity(GO:0004938)
0.0 0.1 GO:0004889 acetylcholine-activated cation-selective channel activity(GO:0004889)
0.0 0.3 GO:0003724 RNA helicase activity(GO:0003724)
0.0 0.0 GO:0008332 low voltage-gated calcium channel activity(GO:0008332)
0.0 0.0 GO:0050510 N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity(GO:0050510)
0.0 0.1 GO:0004616 phosphogluconate dehydrogenase (decarboxylating) activity(GO:0004616)
0.0 0.2 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 0.1 GO:0016997 exo-alpha-sialidase activity(GO:0004308) alpha-sialidase activity(GO:0016997)
0.0 0.0 GO:0004966 galanin receptor activity(GO:0004966)
0.0 0.0 GO:0004597 peptide-aspartate beta-dioxygenase activity(GO:0004597)
0.0 0.1 GO:0031210 phosphatidylcholine binding(GO:0031210)
0.0 0.0 GO:0061133 endopeptidase activator activity(GO:0061133)
0.0 0.0 GO:0016520 growth hormone-releasing hormone receptor activity(GO:0016520)
0.0 0.0 GO:0008853 exodeoxyribonuclease III activity(GO:0008853)
0.0 0.0 GO:0033765 steroid dehydrogenase activity, acting on the CH-CH group of donors(GO:0033765)
0.0 0.1 GO:0017075 syntaxin-1 binding(GO:0017075)
0.0 0.0 GO:0016314 phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity(GO:0016314)
0.0 0.1 GO:0008526 phosphatidylinositol transporter activity(GO:0008526)
0.0 0.0 GO:0050682 AF-2 domain binding(GO:0050682)
0.0 0.1 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.0 0.9 GO:0017124 SH3 domain binding(GO:0017124)
0.0 0.1 GO:0016500 protein-hormone receptor activity(GO:0016500)
0.0 0.1 GO:0016889 endodeoxyribonuclease activity, producing 3'-phosphomonoesters(GO:0016889)
0.0 0.0 GO:0008242 omega peptidase activity(GO:0008242)
0.0 0.1 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.0 0.0 GO:0019870 potassium channel inhibitor activity(GO:0019870)
0.0 0.2 GO:0005246 calcium channel regulator activity(GO:0005246)
0.0 0.0 GO:0034711 inhibin binding(GO:0034711)
0.0 0.1 GO:0016018 cyclosporin A binding(GO:0016018)
0.0 0.1 GO:0070087 chromo shadow domain binding(GO:0070087)
0.0 0.1 GO:0043395 heparan sulfate proteoglycan binding(GO:0043395)
0.0 0.1 GO:0016421 CoA carboxylase activity(GO:0016421)
0.0 0.0 GO:0050694 galactosylceramide sulfotransferase activity(GO:0001733) galactose 3-O-sulfotransferase activity(GO:0050694)
0.0 0.0 GO:0016774 phosphotransferase activity, carboxyl group as acceptor(GO:0016774)
0.0 0.1 GO:0004459 L-lactate dehydrogenase activity(GO:0004459)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.2 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.1 3.6 PID CD8 TCR PATHWAY TCR signaling in naïve CD8+ T cells
0.1 0.9 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.1 1.2 PID IL2 STAT5 PATHWAY IL2 signaling events mediated by STAT5
0.1 1.0 PID TCR PATHWAY TCR signaling in naïve CD4+ T cells
0.1 1.6 PID ERBB1 INTERNALIZATION PATHWAY Internalization of ErbB1
0.0 0.2 PID TXA2PATHWAY Thromboxane A2 receptor signaling
0.0 0.3 SA PTEN PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.0 1.5 PID NFAT 3PATHWAY Role of Calcineurin-dependent NFAT signaling in lymphocytes
0.0 0.2 ST PAC1 RECEPTOR PATHWAY PAC1 Receptor Pathway
0.0 0.7 PID REELIN PATHWAY Reelin signaling pathway
0.0 0.1 PID LPA4 PATHWAY LPA4-mediated signaling events
0.0 0.5 PID S1P S1P3 PATHWAY S1P3 pathway
0.0 0.8 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.0 0.5 PID IL27 PATHWAY IL27-mediated signaling events
0.0 1.0 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0 0.3 PID NFKAPPAB CANONICAL PATHWAY Canonical NF-kappaB pathway
0.0 0.5 PID IFNG PATHWAY IFN-gamma pathway
0.0 0.6 PID MYC PATHWAY C-MYC pathway
0.0 0.3 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.0 0.3 PID THROMBIN PAR1 PATHWAY PAR1-mediated thrombin signaling events
0.0 0.0 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.0 0.4 PID ARF 3PATHWAY Arf1 pathway
0.0 0.5 PID ECADHERIN NASCENT AJ PATHWAY E-cadherin signaling in the nascent adherens junction
0.0 0.7 PID TNF PATHWAY TNF receptor signaling pathway
0.0 0.1 ST DIFFERENTIATION PATHWAY IN PC12 CELLS Differentiation Pathway in PC12 Cells; this is a specific case of PAC1 Receptor Pathway.
0.0 0.3 PID THROMBIN PAR4 PATHWAY PAR4-mediated thrombin signaling events
0.0 0.1 ST ERK1 ERK2 MAPK PATHWAY ERK1/ERK2 MAPK Pathway
0.0 0.2 PID BCR 5PATHWAY BCR signaling pathway
0.0 0.1 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
0.0 0.2 PID RAC1 REG PATHWAY Regulation of RAC1 activity
0.0 0.3 PID RAS PATHWAY Regulation of Ras family activation
0.0 0.1 ST TUMOR NECROSIS FACTOR PATHWAY Tumor Necrosis Factor Pathway.
0.0 0.1 PID P38 ALPHA BETA PATHWAY Regulation of p38-alpha and p38-beta
0.0 0.0 SIG IL4RECEPTOR IN B LYPHOCYTES Genes related to IL4 rceptor signaling in B lymphocytes
0.0 0.2 SA CASPASE CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.0 0.0 PID EPO PATHWAY EPO signaling pathway
0.0 0.1 ST JNK MAPK PATHWAY JNK MAPK Pathway
0.0 0.2 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.0 0.1 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.0 0.4 PID PS1 PATHWAY Presenilin action in Notch and Wnt signaling
0.0 0.5 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 0.1 PID PI3KCI PATHWAY Class I PI3K signaling events
0.0 0.5 PID AURORA B PATHWAY Aurora B signaling
0.0 0.0 PID IL5 PATHWAY IL5-mediated signaling events
0.0 0.3 PID INTEGRIN A4B1 PATHWAY Alpha4 beta1 integrin signaling events
0.0 0.2 PID IL12 2PATHWAY IL12-mediated signaling events
0.0 0.5 NABA COLLAGENS Genes encoding collagen proteins
0.0 0.3 PID CONE PATHWAY Visual signal transduction: Cones
0.0 0.2 PID CERAMIDE PATHWAY Ceramide signaling pathway
0.0 0.1 PID PDGFRB PATHWAY PDGFR-beta signaling pathway
0.0 0.0 PID IL2 1PATHWAY IL2-mediated signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.7 REACTOME PECAM1 INTERACTIONS Genes involved in PECAM1 interactions
0.2 0.7 REACTOME BINDING AND ENTRY OF HIV VIRION Genes involved in Binding and entry of HIV virion
0.1 1.5 REACTOME GENERATION OF SECOND MESSENGER MOLECULES Genes involved in Generation of second messenger molecules
0.1 1.4 REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.1 1.1 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.1 1.2 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.1 0.7 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
0.1 0.4 REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
0.1 0.5 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
0.1 0.8 REACTOME RAP1 SIGNALLING Genes involved in Rap1 signalling
0.0 0.5 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.0 0.2 REACTOME IRAK1 RECRUITS IKK COMPLEX Genes involved in IRAK1 recruits IKK complex
0.0 0.3 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
0.0 0.0 REACTOME PROSTACYCLIN SIGNALLING THROUGH PROSTACYCLIN RECEPTOR Genes involved in Prostacyclin signalling through prostacyclin receptor
0.0 0.2 REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY Genes involved in Regulation of the Fanconi anemia pathway
0.0 0.3 REACTOME PROSTANOID LIGAND RECEPTORS Genes involved in Prostanoid ligand receptors
0.0 0.9 REACTOME EGFR DOWNREGULATION Genes involved in EGFR downregulation
0.0 0.3 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.0 0.5 REACTOME CTNNB1 PHOSPHORYLATION CASCADE Genes involved in Beta-catenin phosphorylation cascade
0.0 0.6 REACTOME IL RECEPTOR SHC SIGNALING Genes involved in Interleukin receptor SHC signaling
0.0 0.7 REACTOME COSTIMULATION BY THE CD28 FAMILY Genes involved in Costimulation by the CD28 family
0.0 0.6 REACTOME DOWNSTREAM TCR SIGNALING Genes involved in Downstream TCR signaling
0.0 0.9 REACTOME SEMA4D IN SEMAPHORIN SIGNALING Genes involved in Sema4D in semaphorin signaling
0.0 0.4 REACTOME PROCESSING OF INTRONLESS PRE MRNAS Genes involved in Processing of Intronless Pre-mRNAs
0.0 0.1 REACTOME N GLYCAN ANTENNAE ELONGATION IN THE MEDIAL TRANS GOLGI Genes involved in N-glycan antennae elongation in the medial/trans-Golgi
0.0 0.7 REACTOME RORA ACTIVATES CIRCADIAN EXPRESSION Genes involved in RORA Activates Circadian Expression
0.0 0.2 REACTOME ENDOSOMAL VACUOLAR PATHWAY Genes involved in Endosomal/Vacuolar pathway
0.0 0.5 REACTOME CHONDROITIN SULFATE BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
0.0 0.6 REACTOME KERATAN SULFATE KERATIN METABOLISM Genes involved in Keratan sulfate/keratin metabolism
0.0 0.3 REACTOME PRE NOTCH TRANSCRIPTION AND TRANSLATION Genes involved in Pre-NOTCH Transcription and Translation
0.0 0.1 REACTOME REGULATION OF INSULIN SECRETION BY GLUCAGON LIKE PEPTIDE1 Genes involved in Regulation of Insulin Secretion by Glucagon-like Peptide-1
0.0 0.3 REACTOME HIGHLY CALCIUM PERMEABLE POSTSYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Highly calcium permeable postsynaptic nicotinic acetylcholine receptors
0.0 0.0 REACTOME MRNA CAPPING Genes involved in mRNA Capping
0.0 0.1 REACTOME G PROTEIN ACTIVATION Genes involved in G-protein activation
0.0 1.1 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0 0.8 REACTOME INTERFERON GAMMA SIGNALING Genes involved in Interferon gamma signaling
0.0 0.1 REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.0 0.3 REACTOME NUCLEOTIDE LIKE PURINERGIC RECEPTORS Genes involved in Nucleotide-like (purinergic) receptors
0.0 0.0 REACTOME DESTABILIZATION OF MRNA BY BRF1 Genes involved in Destabilization of mRNA by Butyrate Response Factor 1 (BRF1)
0.0 0.1 REACTOME PKA MEDIATED PHOSPHORYLATION OF CREB Genes involved in PKA-mediated phosphorylation of CREB
0.0 0.2 REACTOME ASSOCIATION OF LICENSING FACTORS WITH THE PRE REPLICATIVE COMPLEX Genes involved in Association of licensing factors with the pre-replicative complex
0.0 0.4 REACTOME G ALPHA Z SIGNALLING EVENTS Genes involved in G alpha (z) signalling events
0.0 0.2 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.0 0.0 REACTOME PLATELET CALCIUM HOMEOSTASIS Genes involved in Platelet calcium homeostasis
0.0 0.1 REACTOME ABORTIVE ELONGATION OF HIV1 TRANSCRIPT IN THE ABSENCE OF TAT Genes involved in Abortive elongation of HIV-1 transcript in the absence of Tat
0.0 0.3 REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.0 0.3 REACTOME G BETA GAMMA SIGNALLING THROUGH PI3KGAMMA Genes involved in G beta:gamma signalling through PI3Kgamma
0.0 0.2 REACTOME P38MAPK EVENTS Genes involved in p38MAPK events
0.0 0.0 REACTOME REGULATION OF GLUCOKINASE BY GLUCOKINASE REGULATORY PROTEIN Genes involved in Regulation of Glucokinase by Glucokinase Regulatory Protein
0.0 0.0 REACTOME AUTODEGRADATION OF THE E3 UBIQUITIN LIGASE COP1 Genes involved in Autodegradation of the E3 ubiquitin ligase COP1
0.0 0.5 REACTOME GLYCOSPHINGOLIPID METABOLISM Genes involved in Glycosphingolipid metabolism
0.0 0.0 REACTOME VIF MEDIATED DEGRADATION OF APOBEC3G Genes involved in Vif-mediated degradation of APOBEC3G
0.0 0.2 REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING Genes involved in Formation of ATP by chemiosmotic coupling
0.0 0.2 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.0 0.2 REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.0 0.1 REACTOME DAG AND IP3 SIGNALING Genes involved in DAG and IP3 signaling
0.0 0.1 REACTOME MRNA PROCESSING Genes involved in mRNA Processing
0.0 0.2 REACTOME REGULATION OF AMPK ACTIVITY VIA LKB1 Genes involved in Regulation of AMPK activity via LKB1
0.0 0.1 REACTOME PROLONGED ERK ACTIVATION EVENTS Genes involved in Prolonged ERK activation events
0.0 0.1 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.0 0.5 REACTOME PYRUVATE METABOLISM AND CITRIC ACID TCA CYCLE Genes involved in Pyruvate metabolism and Citric Acid (TCA) cycle
0.0 0.0 REACTOME INSULIN RECEPTOR RECYCLING Genes involved in Insulin receptor recycling
0.0 0.2 REACTOME G0 AND EARLY G1 Genes involved in G0 and Early G1
0.0 0.0 REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION Genes involved in activated TAK1 mediates p38 MAPK activation
0.0 0.2 REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.0 0.0 REACTOME RIP MEDIATED NFKB ACTIVATION VIA DAI Genes involved in RIP-mediated NFkB activation via DAI
0.0 0.2 REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription