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ENCODE: H3K4me1 ChIP-Seq of primary human cells

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Results for PGR

Z-value: 2.57

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Transcription factors associated with PGR

Gene Symbol	Gene ID	Gene Info
PGR Ensembl NCBI GeneCards UniProt	ENSG00000082175.10	progesterone receptor

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE	Gene	Distance	Association probability	Pearson corr. coef.	P-value	Plot
chr11_100998153_100998410	PGR	1520	0.552946	-0.81	8.4e-03	Click!
chr11_100998762_100998913	PGR	964	0.707522	-0.56	1.2e-01	Click!
chr11_100998523_100998674	PGR	1203	0.631733	-0.55	1.2e-01	Click!
chr11_100997860_100998011	PGR	1866	0.490919	-0.51	1.6e-01	Click!

Activity of the PGR motif across conditions

Conditions sorted by the z-value of the PGR motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE)	Target Score	Top associated gene	Gene Info	Distance of CRE to TSS	CRE/Gene association probability
chr22_40719905_40720423	0.44	ADSL	adenylosuccinate lyase	22343	0.17
chr2_47393877_47394028	0.41	CALM2	calmodulin 2 (phosphorylase kinase, delta)	9698	0.2
chr8_941660_941943	0.41	ERICH1-AS1	ERICH1 antisense RNA 1	108473	0.08
chr2_135029441_135029730	0.40	MGAT5	mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase	17755	0.24
chr11_108114766_108115122	0.40	ENSG00000206967	.	14613	0.15
chr20_51025367_51025552	0.40	ZFP64	ZFP64 zinc finger protein	216934	0.02
chr9_92151633_92152777	0.39	SEMA4D	sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D	39160	0.16
chr4_4462558_4462851	0.38	STX18	syntaxin 18	977	0.59
chr10_80897727_80898445	0.38	ZMIZ1	zinc finger, MIZ-type containing 1	69294	0.12
chr1_9789105_9789546	0.37	PIK3CD	phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta	11198	0.17
chr3_10295585_10295736	0.37	TATDN2	TatD DNase domain containing 2	5064	0.14
chr10_75619235_75619680	0.36	CAMK2G	calcium/calmodulin-dependent protein kinase II gamma	1155	0.34
chr6_143862361_143862526	0.36	PHACTR2	phosphatase and actin regulator 2	4461	0.19
chr13_111837384_111838319	0.36	ARHGEF7	Rho guanine nucleotide exchange factor (GEF) 7	566	0.79
chr4_107274416_107274677	0.36	TBCK	TBC1 domain containing kinase	31894	0.19
chr9_136006860_136007130	0.36	RALGDS	ral guanine nucleotide dissociation stimulator	491	0.74
chr10_72193939_72194090	0.35	AC022532.1	Uncharacterized protein	571	0.72
chr4_15644909_15645060	0.35	FBXL5	F-box and leucine-rich repeat protein 5	1288	0.49
chr16_84858002_84858153	0.35	RP11-254F19.2		3792	0.21
chr6_45981609_45981857	0.35	CLIC5	chloride intracellular channel 5	1832	0.38
chr6_16420351_16420774	0.35	ENSG00000265642	.	8192	0.31
chr3_188156360_188156537	0.35	LPP-AS1	LPP antisense RNA 1	130006	0.05
chr17_8053906_8054187	0.34	PER1	period circadian clock 1	104	0.92
chr11_60878524_60878675	0.34	CD5	CD5 molecule	8618	0.18
chr9_92022718_92022899	0.34	SEMA4D	sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D	1967	0.41
chr2_113943413_113943847	0.34	PSD4	pleckstrin and Sec7 domain containing 4	10227	0.14
chr12_52071969_52072120	0.34	SCN8A	sodium channel, voltage gated, type VIII, alpha subunit	8163	0.27
chr5_39181205_39181356	0.34	FYB	FYN binding protein	21849	0.24
chr2_201924015_201924238	0.34	NDUFB3	NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 3, 12kDa	12030	0.13
chr2_202113259_202113410	0.33	CASP8	caspase 8, apoptosis-related cysteine peptidase	9369	0.19
chr20_50028653_50029381	0.33	ENSG00000263645	.	35159	0.18
chr2_136810090_136810241	0.33	AC093391.2		40130	0.17
chr11_128168877_128169065	0.33	ETS1	v-ets avian erythroblastosis virus E26 oncogene homolog 1	206318	0.03
chr3_56823289_56823680	0.33	ARHGEF3	Rho guanine nucleotide exchange factor (GEF) 3	12493	0.28
chr8_82002361_82002551	0.33	PAG1	phosphoprotein associated with glycosphingolipid microdomains 1	21847	0.26
chr5_130667286_130667437	0.33	CDC42SE2	CDC42 small effector 2	53938	0.17
chr10_28835021_28835418	0.33	WAC	WW domain containing adaptor with coiled-coil	12167	0.2
chr7_27404472_27404623	0.33	EVX1-AS	EVX1 antisense RNA	117699	0.04
chr1_25320280_25320441	0.32	RUNX3	runt-related transcription factor 3	28859	0.16
chr2_30471681_30471976	0.32	LBH	limb bud and heart development	16782	0.23
chr2_204577764_204577915	0.32	CD28	CD28 molecule	6423	0.26
chr8_134562977_134563358	0.32	ST3GAL1	ST3 beta-galactoside alpha-2,3-sialyltransferase 1	20925	0.27
chr7_151840289_151840485	0.32	KMT2C	lysine (K)-specific methyltransferase 2C	503	0.8
chr7_142155820_142156296	0.32	PRSS3P3	protease, serine, 3 pseudogene 3	166449	0.03
chr5_150526605_150526923	0.32	ANXA6	annexin A6	4276	0.24
chr13_41151912_41152184	0.32	AL133318.1	Uncharacterized protein	40725	0.18
chr8_101823524_101823815	0.31	ENSG00000222795	.	20419	0.17
chr16_50802521_50802672	0.31	CYLD	cylindromatosis (turban tumor syndrome)	19136	0.11
chr9_114604147_114604298	0.31	ENSG00000206907	.	2114	0.34
chr11_3760141_3760292	0.31	NUP98	nucleoporin 98kDa	21608	0.1
chr2_113925026_113925412	0.31	PSD4	pleckstrin and Sec7 domain containing 4	6329	0.15
chr8_133990678_133991177	0.31	TG	thyroglobulin	14075	0.25
chr3_16350029_16350306	0.31	RP11-415F23.2		5779	0.18
chr12_47004551_47004702	0.31	SLC38A4	solute carrier family 38, member 4	158461	0.04
chr3_69145351_69145608	0.31	ARL6IP5	ADP-ribosylation-like factor 6 interacting protein 5	11307	0.14
chr8_134303253_134303609	0.30	NDRG1	N-myc downstream regulated 1	5348	0.28
chr15_66687099_66687308	0.30	MAP2K1	mitogen-activated protein kinase kinase 1	8048	0.13
chr1_117917956_117918139	0.30	MAN1A2	mannosidase, alpha, class 1A, member 2	7976	0.3
chr7_148609620_148609917	0.30	ENSG00000239468	.	22462	0.13
chr9_113662694_113662845	0.30	ENSG00000206923	.	2848	0.32
chr10_44312151_44312815	0.30	ZNF32	zinc finger protein 32	168179	0.03
chr20_37491189_37491977	0.30	ENSG00000240474	.	9830	0.2
chrX_78522662_78522933	0.30	GPR174	G protein-coupled receptor 174	96328	0.09
chr1_90116183_90116334	0.30	LRRC8C	leucine rich repeat containing 8 family, member C	17627	0.16
chr15_60868186_60868595	0.30	RORA	RAR-related orphan receptor A	16350	0.2
chr10_22876646_22876797	0.30	PIP4K2A	phosphatidylinositol-5-phosphate 4-kinase, type II, alpha	3883	0.35
chr10_126437876_126438126	0.29	FAM53B	family with sequence similarity 53, member B	5163	0.18
chr14_71421573_71421779	0.29	PCNX	pecanex homolog (Drosophila)	47220	0.19
chr1_175180078_175180229	0.29	KIAA0040	KIAA0040	18074	0.25
chr18_67610582_67610750	0.29	CD226	CD226 molecule	3989	0.34
chr15_64300635_64300804	0.29	DAPK2	death-associated protein kinase 2	31747	0.16
chr17_48965319_48965470	0.29	TOB1	transducer of ERBB2, 1	20055	0.15
chr16_50102313_50102546	0.29	RP11-429P3.3		2294	0.22
chr1_229461032_229461183	0.29	RP4-803J11.2		5957	0.15
chr3_171094795_171095167	0.29	ENSG00000222506	.	62334	0.13
chr2_231196155_231196306	0.29	SP140L	SP140 nuclear body protein-like	4245	0.28
chr14_96593461_96593715	0.29	ENSG00000221236	.	9600	0.19
chr14_99693708_99693994	0.29	AL109767.1		35434	0.17
chr6_108059944_108060120	0.28	SCML4	sex comb on midleg-like 4 (Drosophila)	6433	0.31
chr11_6548040_6548191	0.28	DNHD1	dynein heavy chain domain 1	28669	0.09
chr14_94624184_94624480	0.28	PPP4R4	protein phosphatase 4, regulatory subunit 4	11867	0.17
chr12_12626986_12627137	0.28	DUSP16	dual specificity phosphatase 16	46998	0.15
chr20_43522738_43522936	0.28	YWHAB	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta	8444	0.15
chr7_149543340_149543491	0.28	ZNF862	zinc finger protein 862	7951	0.17
chr17_81028924_81029552	0.28	METRNL	meteorin, glial cell differentiation regulator-like	8329	0.22
chr2_106394710_106394861	0.28	NCK2	NCK adaptor protein 2	32597	0.22
chr7_76921945_76922096	0.28	GSAP	gamma-secretase activating protein	33543	0.17
chr13_42968762_42968913	0.28	AKAP11	A kinase (PRKA) anchor protein 11	122548	0.06
chr9_97589360_97589511	0.28	RP11-49O14.3		2881	0.25
chr6_147644361_147644521	0.28	STXBP5	syntaxin binding protein 5 (tomosyn)	3868	0.37
chr10_27087573_27087735	0.28	ENSG00000206605	.	8079	0.19
chr10_35374638_35374834	0.28	CUL2	cullin 2	4556	0.18
chr11_114086673_114087539	0.28	NNMT	nicotinamide N-methyltransferase	41447	0.17
chr4_76442938_76443089	0.28	RCHY1	ring finger and CHY zinc finger domain containing 1, E3 ubiquitin protein ligase	3118	0.24
chr14_74516670_74516821	0.28	CCDC176	coiled-coil domain containing 176	5491	0.16
chr5_35790123_35790325	0.28	SPEF2	sperm flagellar 2	10954	0.22
chr22_32876313_32876464	0.27	FBXO7	F-box protein 7	4808	0.21
chr14_107175089_107175555	0.27	IGHV2-70	immunoglobulin heavy variable 2-70	4016	0.05
chr3_150923497_150923774	0.27	GPR171	G protein-coupled receptor 171	2647	0.22
chr2_25495296_25495711	0.27	DNMT3A	DNA (cytosine-5-)-methyltransferase 3 alpha	20323	0.2
chr7_44668438_44669074	0.27	OGDH	oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide)	4695	0.22
chr15_78339069_78339553	0.27	ENSG00000221476	.	8438	0.14
chr14_99659688_99659839	0.27	AL162151.4		35010	0.19
chr6_91001741_91001892	0.27	BACH2	BTB and CNC homology 1, basic leucine zipper transcription factor 2	4645	0.27
chr11_108097039_108097242	0.27	ATM	ataxia telangiectasia mutated	2335	0.22
chr14_61557835_61557986	0.27	SLC38A6	solute carrier family 38, member 6	48042	0.15
chr4_164593002_164593153	0.27	MARCH1	membrane-associated ring finger (C3HC4) 1, E3 ubiquitin protein ligase	58391	0.15
chr14_68792413_68792564	0.27	RAD51B	RAD51 paralog B	85739	0.09
chr3_43796991_43797142	0.27	ABHD5	abhydrolase domain containing 5	43867	0.18
chr8_125575470_125576116	0.27	MTSS1	metastasis suppressor 1	2175	0.26
chr17_26876127_26876878	0.27	UNC119	unc-119 homolog (C. elegans)	85	0.93
chr10_126386807_126387279	0.26	FAM53B-AS1	FAM53B antisense RNA 1	5151	0.23
chr11_110341183_110341334	0.26	FDX1	ferredoxin 1	40651	0.21
chr3_114052154_114052373	0.26	ENSG00000207770	.	16847	0.16
chr3_133209932_133210083	0.26	BFSP2-AS1	BFSP2 antisense RNA 1	35387	0.16
chr13_74705428_74705642	0.26	KLF12	Kruppel-like factor 12	2859	0.42
chr6_112125443_112125653	0.26	FYN	FYN oncogene related to SRC, FGR, YES	5922	0.3
chr3_131520972_131521123	0.26	CPNE4	copine IV	123378	0.06
chrX_23802791_23803324	0.26	SAT1	spermidine/spermine N1-acetyltransferase 1	1767	0.23
chr6_106628525_106628811	0.26	RP1-134E15.3		80653	0.08
chr8_41334799_41334950	0.26	GOLGA7	golgin A7	13041	0.18
chr6_3868238_3868436	0.26	FAM50B	family with sequence similarity 50, member B	18715	0.2
chr14_71124948_71125129	0.26	TTC9	tetratricopeptide repeat domain 9	16534	0.2
chr1_114314007_114314272	0.26	PHTF1	putative homeodomain transcription factor 1	12041	0.18
chr2_162871199_162871350	0.26	AC008063.2		58492	0.12
chr1_100830854_100831005	0.26	CDC14A	cell division cycle 14A	12424	0.18
chr7_38261465_38261616	0.26	STARD3NL	STARD3 N-terminal like	43543	0.2
chr2_197995272_197995665	0.26	ANKRD44	ankyrin repeat domain 44	8011	0.27
chr10_33439132_33439327	0.26	NRP1	neuropilin 1	35354	0.17
chr2_10472354_10472745	0.26	HPCAL1	hippocalcin-like 1	28723	0.15
chr3_46394034_46394455	0.26	CCR2	chemokine (C-C motif) receptor 2	981	0.53
chr2_158273515_158274051	0.26	CYTIP	cytohesin 1 interacting protein	22143	0.2
chr10_112618995_112619585	0.25	PDCD4	programmed cell death 4 (neoplastic transformation inhibitor)	12275	0.14
chr8_124099579_124099969	0.25	TBC1D31	TBC1 domain family, member 31	6127	0.18
chr1_111738933_111739395	0.25	DENND2D	DENN/MADD domain containing 2D	4147	0.14
chr11_112748912_112749352	0.25	RP11-629G13.1		82889	0.09
chr11_64528507_64528709	0.25	PYGM	phosphorylase, glycogen, muscle	839	0.47
chr11_48063752_48063903	0.25	AC103828.1		26420	0.18
chr10_11275555_11276261	0.25	RP3-323N1.2		62569	0.12
chr1_109964305_109964456	0.25	PSMA5	proteasome (prosome, macropain) subunit, alpha type, 5	4593	0.16
chr12_65085302_65085472	0.25	AC025262.1	Mesenchymal stem cell protein DSC96; Uncharacterized protein	4942	0.17
chr13_100032613_100033027	0.25	ENSG00000207719	.	24435	0.18
chr3_105582815_105583041	0.25	CBLB	Cbl proto-oncogene B, E3 ubiquitin protein ligase	4959	0.37
chr14_72061251_72061402	0.25	SIPA1L1	signal-induced proliferation-associated 1 like 1	3625	0.37
chr4_123356495_123356646	0.25	IL2	interleukin 2	21310	0.22
chr1_66741246_66741518	0.25	PDE4B	phosphodiesterase 4B, cAMP-specific	18052	0.28
chr3_196474181_196474332	0.25	ENSG00000272359	.	61	0.96
chr16_3899065_3899268	0.25	CREBBP	CREB binding protein	30955	0.18
chr12_66684119_66684270	0.25	ENSG00000222744	.	2269	0.26
chr8_125884475_125884626	0.25	ENSG00000263735	.	50250	0.14
chr11_66413680_66413831	0.25	RBM4	RNA binding motif protein 4	7349	0.1
chr5_40672680_40672956	0.25	PTGER4	prostaglandin E receptor 4 (subtype EP4)	6782	0.22
chr14_88480135_88480311	0.25	RP11-300J18.2		1732	0.33
chr12_58174546_58174758	0.25	TSFM	Ts translation elongation factor, mitochondrial	1720	0.14
chr1_29492039_29492190	0.25	RP11-242O24.5		13113	0.15
chr14_23000021_23000410	0.24	TRAJ15	T cell receptor alpha joining 15	1635	0.24
chr13_25193371_25193571	0.24	ENSG00000211508	.	10254	0.2
chr19_3950919_3951410	0.24	DAPK3	death-associated protein kinase 3	9993	0.1
chr3_154867378_154867529	0.24	MME-AS1	MME antisense RNA 1	33621	0.22
chr4_140819733_140819884	0.24	MAML3	mastermind-like 3 (Drosophila)	7687	0.29
chr11_60761122_60761414	0.24	ENSG00000207153	.	8629	0.13
chr2_11471370_11471521	0.24	ROCK2	Rho-associated, coiled-coil containing protein kinase 2	13266	0.23
chr2_225806071_225806268	0.24	DOCK10	dedicator of cytokinesis 10	5613	0.32
chr2_85071612_85071979	0.24	TRABD2A	TraB domain containing 2A	36411	0.15
chr17_78786573_78786901	0.24	RP11-28G8.1		7305	0.25
chr4_78744780_78744931	0.24	CNOT6L	CCR4-NOT transcription complex, subunit 6-like	4086	0.3
chr3_112719564_112719819	0.24	GTPBP8	GTP-binding protein 8 (putative)	9277	0.14
chr8_121748012_121748163	0.24	RP11-713M15.1		25406	0.23
chr17_17753098_17753798	0.24	TOM1L2	target of myb1-like 2 (chicken)	12646	0.14
chr15_61135667_61135839	0.24	RP11-554D20.1		78814	0.11
chr11_587585_588264	0.24	PHRF1	PHD and ring finger domains 1	11403	0.07
chr5_14415347_14415596	0.24	TRIO	trio Rho guanine nucleotide exchange factor	73086	0.13
chr3_196404701_196405150	0.24	ENSG00000201441	.	30910	0.1
chr7_32628711_32628871	0.24	AVL9	AVL9 homolog (S. cerevisiase)	45924	0.18
chr15_67407609_67407887	0.24	SMAD3	SMAD family member 3	10306	0.24
chr4_109095665_109095816	0.23	ENSG00000232021	.	1165	0.55
chr10_945205_945384	0.23	LARP4B	La ribonucleoprotein domain family, member 4B	4161	0.24
chr14_72917347_72917498	0.23	RGS6	regulator of G-protein signaling 6	3806	0.38
chr17_46912636_46912982	0.23	CALCOCO2	calcium binding and coiled-coil domain 2	4219	0.14
chr20_57844647_57845067	0.23	EDN3	endothelin 3	30625	0.2
chr3_170982645_170982911	0.23	TNIK	TRAF2 and NCK interacting kinase	39278	0.21
chr15_50194108_50194259	0.23	ATP8B4	ATPase, class I, type 8B, member 4	6107	0.24
chr12_93825039_93825190	0.23	UBE2N	ubiquitin-conjugating enzyme E2N	9918	0.15
chr13_97867179_97867538	0.23	MBNL2	muscleblind-like splicing regulator 2	6330	0.31
chr2_225858106_225858257	0.23	ENSG00000263828	.	17076	0.26
chr6_492948_493099	0.23	RP1-20B11.2		31148	0.23
chr5_93947809_93947960	0.23	CTC-303L1.2		5943	0.18
chr14_61965734_61966388	0.23	RP11-47I22.4		29785	0.17
chr10_104555085_104555236	0.23	ENSG00000252994	.	8526	0.14
chr6_139484130_139484281	0.23	HECA	headcase homolog (Drosophila)	27956	0.2
chr8_19414017_19414313	0.23	CSGALNACT1	chondroitin sulfate N-acetylgalactosaminyltransferase 1	45211	0.2
chr1_111182407_111182558	0.23	KCNA2	potassium voltage-gated channel, shaker-related subfamily, member 2	8386	0.18
chr8_128137659_128137810	0.23	POU5F1B	POU class 5 homeobox 1B	288801	0.01
chr4_143271202_143271432	0.23	INPP4B	inositol polyphosphate-4-phosphatase, type II, 105kDa	44220	0.22
chr2_175500944_175501126	0.23	WIPF1	WAS/WASL interacting protein family, member 1	1728	0.41
chr8_64085269_64085426	0.23	YTHDF3	YTH domain family, member 3	4133	0.3
chr6_131946686_131946837	0.23	MED23	mediator complex subunit 23	2439	0.23
chr1_156814375_156814655	0.23	INSRR	insulin receptor-related receptor	14295	0.11
chr3_18766491_18766692	0.23	ENSG00000228956	.	20645	0.29
chr2_37860606_37860964	0.23	CDC42EP3	CDC42 effector protein (Rho GTPase binding) 3	14016	0.24

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of PGR

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	0.5	GO:0032714	negative regulation of interleukin-5 production(GO:0032714)
0.2	0.6	GO:0002669	lymphocyte anergy(GO:0002249) regulation of T cell anergy(GO:0002667) positive regulation of T cell anergy(GO:0002669) T cell anergy(GO:0002870) regulation of lymphocyte anergy(GO:0002911) positive regulation of lymphocyte anergy(GO:0002913)
0.2	0.8	GO:0045589	regulation of regulatory T cell differentiation(GO:0045589)
0.2	0.8	GO:1901339	activation of store-operated calcium channel activity(GO:0032237) regulation of store-operated calcium channel activity(GO:1901339) positive regulation of store-operated calcium channel activity(GO:1901341)
0.2	0.6	GO:0010459	negative regulation of heart rate(GO:0010459)
0.2	0.5	GO:0019276	UDP-N-acetylgalactosamine metabolic process(GO:0019276)
0.1	0.4	GO:0001831	trophectodermal cellular morphogenesis(GO:0001831)
0.1	0.7	GO:0002710	negative regulation of T cell mediated immunity(GO:0002710)
0.1	0.4	GO:0007221	positive regulation of transcription of Notch receptor target(GO:0007221)
0.1	0.5	GO:0043615	astrocyte cell migration(GO:0043615)
0.1	0.4	GO:0018076	N-terminal peptidyl-lysine acetylation(GO:0018076)
0.1	0.1	GO:0042091	interleukin-10 biosynthetic process(GO:0042091) regulation of interleukin-10 biosynthetic process(GO:0045074)
0.1	0.2	GO:0001766	membrane raft polarization(GO:0001766) membrane raft distribution(GO:0031580)
0.1	0.2	GO:0050862	positive regulation of T cell receptor signaling pathway(GO:0050862)
0.1	0.5	GO:0045059	positive thymic T cell selection(GO:0045059)
0.1	0.6	GO:0007172	signal complex assembly(GO:0007172)
0.1	0.7	GO:0002837	regulation of response to tumor cell(GO:0002834) positive regulation of response to tumor cell(GO:0002836) regulation of immune response to tumor cell(GO:0002837) positive regulation of immune response to tumor cell(GO:0002839)
0.1	0.3	GO:0045056	transcytosis(GO:0045056)
0.1	0.2	GO:0002677	negative regulation of chronic inflammatory response(GO:0002677)
0.1	2.5	GO:0050690	regulation of defense response to virus by virus(GO:0050690)
0.1	0.3	GO:0090286	cytoskeletal anchoring at nuclear membrane(GO:0090286)
0.1	0.3	GO:0030854	positive regulation of granulocyte differentiation(GO:0030854)
0.1	0.2	GO:0032656	regulation of interleukin-13 production(GO:0032656)
0.1	0.2	GO:0050710	negative regulation of cytokine secretion(GO:0050710)
0.1	0.4	GO:0042989	sequestering of actin monomers(GO:0042989)
0.1	0.3	GO:0060437	lung growth(GO:0060437)
0.1	0.2	GO:0048861	leukemia inhibitory factor signaling pathway(GO:0048861)
0.1	0.2	GO:0061154	endothelial tube morphogenesis(GO:0061154)
0.1	0.4	GO:0048096	chromatin-mediated maintenance of transcription(GO:0048096)
0.1	0.2	GO:0045722	positive regulation of gluconeogenesis(GO:0045722)
0.1	0.2	GO:0048742	regulation of skeletal muscle fiber development(GO:0048742)
0.1	0.1	GO:0042996	regulation of Golgi to plasma membrane protein transport(GO:0042996)
0.1	0.2	GO:0002313	mature B cell differentiation involved in immune response(GO:0002313)
0.1	0.3	GO:0050687	negative regulation of defense response to virus(GO:0050687)
0.1	0.5	GO:0006491	N-glycan processing(GO:0006491)
0.1	0.4	GO:0006198	cAMP catabolic process(GO:0006198)
0.1	0.2	GO:0035405	histone-threonine phosphorylation(GO:0035405)
0.1	0.1	GO:0002335	mature B cell differentiation(GO:0002335)
0.1	0.7	GO:0051828	entry into host cell(GO:0030260) entry into host(GO:0044409) entry into cell of other organism involved in symbiotic interaction(GO:0051806) entry into other organism involved in symbiotic interaction(GO:0051828)
0.1	0.2	GO:0043383	negative T cell selection(GO:0043383)
0.1	0.1	GO:0019049	evasion or tolerance of host defenses by virus(GO:0019049) avoidance of host defenses(GO:0044413) evasion or tolerance of host defenses(GO:0044415) avoidance of defenses of other organism involved in symbiotic interaction(GO:0051832) evasion or tolerance of defenses of other organism involved in symbiotic interaction(GO:0051834)
0.1	0.1	GO:0033087	negative regulation of immature T cell proliferation(GO:0033087) negative regulation of immature T cell proliferation in thymus(GO:0033088)
0.1	0.5	GO:0043550	regulation of lipid kinase activity(GO:0043550)
0.1	0.1	GO:0072600	protein targeting to Golgi(GO:0000042) establishment of protein localization to Golgi(GO:0072600)
0.1	0.2	GO:0006104	succinyl-CoA metabolic process(GO:0006104)
0.1	0.2	GO:0010761	fibroblast migration(GO:0010761)
0.1	0.1	GO:0010572	positive regulation of platelet activation(GO:0010572)
0.1	0.3	GO:0032733	positive regulation of interleukin-10 production(GO:0032733)
0.1	0.2	GO:0060088	auditory receptor cell morphogenesis(GO:0002093) auditory receptor cell stereocilium organization(GO:0060088)
0.1	0.2	GO:0035066	positive regulation of histone acetylation(GO:0035066) positive regulation of protein acetylation(GO:1901985) positive regulation of peptidyl-lysine acetylation(GO:2000758)
0.1	0.1	GO:0051497	negative regulation of stress fiber assembly(GO:0051497)
0.1	0.3	GO:0050847	progesterone receptor signaling pathway(GO:0050847)
0.1	0.2	GO:0097300	necroptotic process(GO:0070266) programmed necrotic cell death(GO:0097300)
0.1	0.3	GO:0070670	response to interleukin-4(GO:0070670)
0.0	0.1	GO:0032506	cytokinetic process(GO:0032506)
0.0	0.0	GO:0033689	negative regulation of osteoblast proliferation(GO:0033689)
0.0	0.2	GO:0071480	cellular response to gamma radiation(GO:0071480)
0.0	0.1	GO:0052257	pathogen-associated molecular pattern dependent induction by symbiont of host innate immune response(GO:0052033) positive regulation by symbiont of host innate immune response(GO:0052166) modulation by symbiont of host innate immune response(GO:0052167) pathogen-associated molecular pattern dependent modulation by symbiont of host innate immune response(GO:0052169) pathogen-associated molecular pattern dependent induction by organism of innate immune response of other organism involved in symbiotic interaction(GO:0052257) positive regulation by organism of innate immune response in other organism involved in symbiotic interaction(GO:0052305) modulation by organism of innate immune response in other organism involved in symbiotic interaction(GO:0052306) pathogen-associated molecular pattern dependent modulation by organism of innate immune response in other organism involved in symbiotic interaction(GO:0052308)
0.0	0.1	GO:0045046	protein import into peroxisome membrane(GO:0045046)
0.0	0.0	GO:0060028	convergent extension involved in axis elongation(GO:0060028)
0.0	0.1	GO:0034392	negative regulation of smooth muscle cell apoptotic process(GO:0034392)
0.0	0.2	GO:0060159	regulation of dopamine receptor signaling pathway(GO:0060159)
0.0	0.1	GO:0032232	negative regulation of actin filament bundle assembly(GO:0032232)
0.0	0.1	GO:0034219	carbohydrate transmembrane transport(GO:0034219)
0.0	0.1	GO:0051573	negative regulation of histone H3-K9 methylation(GO:0051573)
0.0	0.1	GO:0045343	MHC class I biosynthetic process(GO:0045341) regulation of MHC class I biosynthetic process(GO:0045343)
0.0	0.1	GO:0070682	proteasome regulatory particle assembly(GO:0070682)
0.0	0.1	GO:0071379	cellular response to prostaglandin stimulus(GO:0071379)
0.0	0.3	GO:0048535	lymph node development(GO:0048535)
0.0	0.2	GO:0010508	positive regulation of autophagy(GO:0010508)
0.0	0.1	GO:0017014	protein nitrosylation(GO:0017014) peptidyl-cysteine S-nitrosylation(GO:0018119)
0.0	0.1	GO:0046666	retinal cell programmed cell death(GO:0046666)
0.0	0.1	GO:0060242	contact inhibition(GO:0060242)
0.0	0.5	GO:0000305	response to oxygen radical(GO:0000305)
0.0	0.6	GO:0010389	regulation of G2/M transition of mitotic cell cycle(GO:0010389) regulation of cell cycle G2/M phase transition(GO:1902749)
0.0	0.0	GO:0032715	negative regulation of interleukin-6 production(GO:0032715)
0.0	0.1	GO:0006346	methylation-dependent chromatin silencing(GO:0006346)
0.0	0.1	GO:0009313	oligosaccharide catabolic process(GO:0009313)
0.0	0.2	GO:0010867	positive regulation of triglyceride biosynthetic process(GO:0010867)
0.0	0.1	GO:0002507	tolerance induction(GO:0002507)
0.0	0.1	GO:0070777	D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
0.0	0.3	GO:2001021	negative regulation of response to DNA damage stimulus(GO:2001021)
0.0	0.1	GO:0010447	response to acidic pH(GO:0010447)
0.0	0.1	GO:0018094	protein polyglycylation(GO:0018094)
0.0	0.2	GO:0042535	positive regulation of tumor necrosis factor biosynthetic process(GO:0042535)
0.0	0.1	GO:0002248	connective tissue replacement involved in inflammatory response wound healing(GO:0002248) connective tissue replacement(GO:0097709)
0.0	0.2	GO:0045898	regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045898)
0.0	0.2	GO:0034755	iron ion transmembrane transport(GO:0034755)
0.0	0.0	GO:0003402	planar cell polarity pathway involved in axis elongation(GO:0003402)
0.0	0.0	GO:0071481	cellular response to X-ray(GO:0071481)
0.0	0.1	GO:0045603	positive regulation of endothelial cell differentiation(GO:0045603)
0.0	0.0	GO:0002407	dendritic cell chemotaxis(GO:0002407) dendritic cell migration(GO:0036336)
0.0	0.1	GO:0010216	maintenance of DNA methylation(GO:0010216)
0.0	0.3	GO:0006030	chitin metabolic process(GO:0006030) chitin catabolic process(GO:0006032)
0.0	0.2	GO:0043984	histone H4-K16 acetylation(GO:0043984)
0.0	0.1	GO:0051533	positive regulation of NFAT protein import into nucleus(GO:0051533)
0.0	0.1	GO:0060972	left/right pattern formation(GO:0060972)
0.0	0.1	GO:0070265	necrotic cell death(GO:0070265)
0.0	0.1	GO:0071364	cellular response to epidermal growth factor stimulus(GO:0071364)
0.0	0.1	GO:0060049	regulation of protein glycosylation(GO:0060049)
0.0	0.2	GO:0048520	positive regulation of behavior(GO:0048520)
0.0	0.1	GO:0042339	keratan sulfate metabolic process(GO:0042339)
0.0	0.1	GO:0035025	positive regulation of Rho protein signal transduction(GO:0035025)
0.0	0.1	GO:0046476	glycosylceramide biosynthetic process(GO:0046476)
0.0	0.1	GO:0021780	spinal cord oligodendrocyte cell differentiation(GO:0021529) spinal cord oligodendrocyte cell fate specification(GO:0021530) oligodendrocyte cell fate specification(GO:0021778) glial cell fate specification(GO:0021780)
0.0	0.0	GO:0071801	regulation of podosome assembly(GO:0071801) positive regulation of podosome assembly(GO:0071803)
0.0	0.1	GO:0046101	hypoxanthine biosynthetic process(GO:0046101)
0.0	0.1	GO:0003056	regulation of vascular smooth muscle contraction(GO:0003056)
0.0	0.1	GO:0021932	hindbrain radial glia guided cell migration(GO:0021932)
0.0	0.1	GO:0032212	positive regulation of telomere maintenance via telomerase(GO:0032212) positive regulation of telomere maintenance via telomere lengthening(GO:1904358)
0.0	0.0	GO:0030812	negative regulation of nucleotide catabolic process(GO:0030812)
0.0	0.1	GO:0034626	fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.0	0.0	GO:0034143	negative regulation of toll-like receptor signaling pathway(GO:0034122) regulation of toll-like receptor 4 signaling pathway(GO:0034143)
0.0	0.0	GO:0072179	nephric duct formation(GO:0072179)
0.0	0.1	GO:0048003	antigen processing and presentation of lipid antigen via MHC class Ib(GO:0048003)
0.0	0.1	GO:0070493	thrombin receptor signaling pathway(GO:0070493)
0.0	0.1	GO:0051182	coenzyme transport(GO:0051182)
0.0	0.1	GO:0060394	negative regulation of pathway-restricted SMAD protein phosphorylation(GO:0060394)
0.0	0.1	GO:0051103	DNA ligation involved in DNA repair(GO:0051103)
0.0	0.5	GO:0016578	histone deubiquitination(GO:0016578)
0.0	0.1	GO:0006530	asparagine catabolic process(GO:0006530) asparagine catabolic process via L-aspartate(GO:0033345)
0.0	0.1	GO:0017183	peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183)
0.0	0.1	GO:0006772	thiamine metabolic process(GO:0006772)
0.0	0.1	GO:0032878	regulation of establishment or maintenance of cell polarity(GO:0032878)
0.0	0.1	GO:0010533	regulation of activation of Janus kinase activity(GO:0010533) positive regulation of activation of Janus kinase activity(GO:0010536)
0.0	0.1	GO:0046015	carbon catabolite regulation of transcription(GO:0045990) regulation of transcription by glucose(GO:0046015)
0.0	0.1	GO:0034145	positive regulation of toll-like receptor 4 signaling pathway(GO:0034145)
0.0	0.0	GO:0060426	lung vasculature development(GO:0060426)
0.0	0.0	GO:0017085	response to insecticide(GO:0017085)
0.0	0.2	GO:0008356	asymmetric cell division(GO:0008356)
0.0	0.3	GO:0043508	negative regulation of JUN kinase activity(GO:0043508)
0.0	0.1	GO:0008298	intracellular mRNA localization(GO:0008298)
0.0	0.3	GO:0006379	mRNA cleavage(GO:0006379)
0.0	0.1	GO:0070837	dehydroascorbic acid transport(GO:0070837)
0.0	0.0	GO:0001779	natural killer cell differentiation(GO:0001779)
0.0	0.1	GO:0071360	cellular response to exogenous dsRNA(GO:0071360)
0.0	0.1	GO:0010903	negative regulation of very-low-density lipoprotein particle remodeling(GO:0010903)
0.0	0.1	GO:0060528	secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development(GO:0060528)
0.0	0.1	GO:0010815	bradykinin catabolic process(GO:0010815)
0.0	0.1	GO:0043951	negative regulation of cAMP-mediated signaling(GO:0043951)
0.0	0.2	GO:0010758	regulation of macrophage chemotaxis(GO:0010758)
0.0	0.3	GO:0000381	regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.0	0.0	GO:0010831	positive regulation of myotube differentiation(GO:0010831)
0.0	0.0	GO:0002360	T cell lineage commitment(GO:0002360)
0.0	0.1	GO:0070672	response to interleukin-15(GO:0070672)
0.0	0.1	GO:0048478	replication fork protection(GO:0048478)
0.0	0.1	GO:0006422	aspartyl-tRNA aminoacylation(GO:0006422)
0.0	0.1	GO:0090023	positive regulation of neutrophil chemotaxis(GO:0090023) positive regulation of neutrophil migration(GO:1902624)
0.0	0.1	GO:0033152	immunoglobulin V(D)J recombination(GO:0033152)
0.0	0.1	GO:0032486	Rap protein signal transduction(GO:0032486)
0.0	0.0	GO:0046642	negative regulation of alpha-beta T cell proliferation(GO:0046642)
0.0	1.7	GO:0050852	T cell receptor signaling pathway(GO:0050852)
0.0	0.1	GO:0060287	epithelial cilium movement(GO:0003351) epithelial cilium movement involved in determination of left/right asymmetry(GO:0060287)
0.0	0.1	GO:0045416	positive regulation of interleukin-8 biosynthetic process(GO:0045416)
0.0	0.2	GO:0016556	mRNA modification(GO:0016556)
0.0	0.2	GO:0006553	lysine metabolic process(GO:0006553) lysine catabolic process(GO:0006554)
0.0	0.1	GO:0060123	regulation of growth hormone secretion(GO:0060123)
0.0	0.1	GO:0002281	macrophage activation involved in immune response(GO:0002281)
0.0	0.1	GO:0009134	nucleoside diphosphate catabolic process(GO:0009134) ribonucleoside diphosphate catabolic process(GO:0009191)
0.0	0.1	GO:0019228	neuronal action potential(GO:0019228)
0.0	0.2	GO:0005513	detection of calcium ion(GO:0005513)
0.0	0.1	GO:0021800	cerebral cortex tangential migration(GO:0021800)
0.0	0.0	GO:0001302	replicative cell aging(GO:0001302)
0.0	0.1	GO:0071371	cellular response to gonadotropin stimulus(GO:0071371)
0.0	0.1	GO:0018106	peptidyl-histidine phosphorylation(GO:0018106)
0.0	0.0	GO:0046121	deoxyribonucleoside catabolic process(GO:0046121)
0.0	0.1	GO:0034616	response to laminar fluid shear stress(GO:0034616)
0.0	0.1	GO:0060218	hematopoietic stem cell differentiation(GO:0060218)
0.0	0.1	GO:0034638	phosphatidylcholine catabolic process(GO:0034638)
0.0	0.1	GO:0016264	gap junction assembly(GO:0016264)
0.0	0.1	GO:0006685	sphingomyelin catabolic process(GO:0006685)
0.0	0.0	GO:0001672	regulation of chromatin assembly or disassembly(GO:0001672)
0.0	0.2	GO:0007035	vacuolar acidification(GO:0007035)
0.0	0.0	GO:0006154	adenosine catabolic process(GO:0006154)
0.0	0.1	GO:0090267	positive regulation of spindle checkpoint(GO:0090232) regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090266) positive regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090267) positive regulation of cell cycle checkpoint(GO:1901978) regulation of mitotic spindle checkpoint(GO:1903504)
0.0	0.1	GO:0050869	negative regulation of B cell activation(GO:0050869)
0.0	0.1	GO:0014055	acetylcholine secretion, neurotransmission(GO:0014055) regulation of acetylcholine secretion, neurotransmission(GO:0014056) acetylcholine secretion(GO:0061526)
0.0	0.1	GO:0032814	regulation of natural killer cell activation(GO:0032814)
0.0	0.0	GO:0043117	positive regulation of vascular permeability(GO:0043117)
0.0	0.0	GO:0010592	positive regulation of lamellipodium assembly(GO:0010592) positive regulation of lamellipodium organization(GO:1902745)
0.0	0.1	GO:0006659	phosphatidylserine biosynthetic process(GO:0006659)
0.0	0.1	GO:0090224	regulation of spindle organization(GO:0090224)
0.0	0.1	GO:0051305	chromosome movement towards spindle pole(GO:0051305)
0.0	0.1	GO:0070172	positive regulation of tooth mineralization(GO:0070172)
0.0	0.0	GO:0045414	regulation of interleukin-8 biosynthetic process(GO:0045414)
0.0	0.1	GO:0045910	negative regulation of DNA recombination(GO:0045910)
0.0	0.1	GO:0042117	monocyte activation(GO:0042117)
0.0	0.1	GO:0043461	proton-transporting ATP synthase complex assembly(GO:0043461) proton-transporting ATP synthase complex biogenesis(GO:0070272)
0.0	0.1	GO:0032075	positive regulation of nuclease activity(GO:0032075)
0.0	0.1	GO:0035024	negative regulation of Rho protein signal transduction(GO:0035024)
0.0	0.0	GO:0070932	histone H3 deacetylation(GO:0070932) histone H4 deacetylation(GO:0070933)
0.0	0.0	GO:0060061	Spemann organizer formation(GO:0060061)
0.0	0.5	GO:1901185	negative regulation of epidermal growth factor receptor signaling pathway(GO:0042059) negative regulation of ERBB signaling pathway(GO:1901185)
0.0	0.1	GO:0045091	regulation of single stranded viral RNA replication via double stranded DNA intermediate(GO:0045091)
0.0	0.1	GO:0048711	positive regulation of astrocyte differentiation(GO:0048711)
0.0	0.1	GO:0001675	acrosome assembly(GO:0001675)
0.0	0.0	GO:0072385	minus-end-directed organelle transport along microtubule(GO:0072385)
0.0	0.1	GO:0010739	positive regulation of protein kinase A signaling(GO:0010739)
0.0	0.1	GO:0032119	sequestering of zinc ion(GO:0032119)
0.0	0.2	GO:0042347	negative regulation of NF-kappaB import into nucleus(GO:0042347)
0.0	0.1	GO:0046477	glycosylceramide catabolic process(GO:0046477)
0.0	0.0	GO:0031427	response to methotrexate(GO:0031427)
0.0	0.1	GO:0034063	stress granule assembly(GO:0034063)
0.0	0.0	GO:0046006	regulation of activated T cell proliferation(GO:0046006)
0.0	0.2	GO:0050930	induction of positive chemotaxis(GO:0050930)
0.0	0.1	GO:0003310	pancreatic A cell differentiation(GO:0003310)
0.0	0.1	GO:0070498	interleukin-1-mediated signaling pathway(GO:0070498)
0.0	0.1	GO:0007021	tubulin complex assembly(GO:0007021)
0.0	0.1	GO:0030505	inorganic diphosphate transport(GO:0030505)
0.0	0.1	GO:0034260	negative regulation of GTPase activity(GO:0034260)
0.0	0.1	GO:0000380	alternative mRNA splicing, via spliceosome(GO:0000380)
0.0	0.1	GO:0035308	negative regulation of dephosphorylation(GO:0035305) negative regulation of protein dephosphorylation(GO:0035308)
0.0	0.1	GO:0036465	synaptic vesicle recycling(GO:0036465) synaptic vesicle endocytosis(GO:0048488) clathrin-mediated endocytosis(GO:0072583)
0.0	0.1	GO:0043330	response to exogenous dsRNA(GO:0043330)
0.0	0.2	GO:0043124	negative regulation of I-kappaB kinase/NF-kappaB signaling(GO:0043124)
0.0	0.1	GO:0006857	oligopeptide transport(GO:0006857)
0.0	0.0	GO:0071883	adrenergic receptor signaling pathway(GO:0071875) activation of MAPK activity by adrenergic receptor signaling pathway(GO:0071883)
0.0	0.0	GO:0032682	negative regulation of chemokine production(GO:0032682) negative regulation of chemokine biosynthetic process(GO:0045079)
0.0	0.1	GO:0061099	negative regulation of protein tyrosine kinase activity(GO:0061099)
0.0	0.1	GO:0061365	positive regulation of lipoprotein lipase activity(GO:0051006) positive regulation of triglyceride lipase activity(GO:0061365)
0.0	0.0	GO:0048670	regulation of collateral sprouting(GO:0048670)
0.0	0.2	GO:0007628	adult walking behavior(GO:0007628) walking behavior(GO:0090659)
0.0	0.0	GO:0007132	meiotic metaphase I(GO:0007132)
0.0	0.1	GO:0015840	urea transport(GO:0015840)
0.0	0.1	GO:0033631	cell-cell adhesion mediated by integrin(GO:0033631)
0.0	0.1	GO:0009051	pentose-phosphate shunt, oxidative branch(GO:0009051)
0.0	0.1	GO:0006089	lactate metabolic process(GO:0006089)
0.0	0.1	GO:0017121	phospholipid scrambling(GO:0017121)
0.0	0.1	GO:0032875	regulation of DNA endoreduplication(GO:0032875) negative regulation of DNA endoreduplication(GO:0032876) DNA endoreduplication(GO:0042023)
0.0	0.1	GO:0003084	positive regulation of systemic arterial blood pressure(GO:0003084)
0.0	0.1	GO:0033169	histone H3-K9 demethylation(GO:0033169)
0.0	0.1	GO:0022614	membrane to membrane docking(GO:0022614)
0.0	0.1	GO:0045672	positive regulation of osteoclast differentiation(GO:0045672)
0.0	0.0	GO:0035413	positive regulation of catenin import into nucleus(GO:0035413)
0.0	0.0	GO:0002523	leukocyte migration involved in inflammatory response(GO:0002523)
0.0	0.0	GO:0050435	beta-amyloid metabolic process(GO:0050435)
0.0	0.1	GO:0032926	negative regulation of activin receptor signaling pathway(GO:0032926)
0.0	0.0	GO:0009143	nucleoside triphosphate catabolic process(GO:0009143)
0.0	0.0	GO:0018125	peptidyl-cysteine methylation(GO:0018125)
0.0	0.1	GO:0006011	UDP-glucose metabolic process(GO:0006011)
0.0	0.0	GO:0031645	negative regulation of neurological system process(GO:0031645)
0.0	0.0	GO:0034983	peptidyl-lysine deacetylation(GO:0034983)
0.0	0.1	GO:0000183	chromatin silencing at rDNA(GO:0000183)
0.0	0.1	GO:0042487	regulation of odontogenesis of dentin-containing tooth(GO:0042487)
0.0	0.1	GO:0015671	oxygen transport(GO:0015671)
0.0	0.0	GO:0043568	positive regulation of insulin-like growth factor receptor signaling pathway(GO:0043568)
0.0	0.1	GO:0042416	dopamine biosynthetic process(GO:0042416)
0.0	0.1	GO:0016572	histone phosphorylation(GO:0016572)
0.0	0.1	GO:0046940	nucleoside monophosphate phosphorylation(GO:0046940)
0.0	0.1	GO:0034370	triglyceride-rich lipoprotein particle remodeling(GO:0034370) very-low-density lipoprotein particle remodeling(GO:0034372)
0.0	0.1	GO:0000019	regulation of mitotic recombination(GO:0000019)
0.0	0.0	GO:0033688	regulation of osteoblast proliferation(GO:0033688)
0.0	0.1	GO:0045292	mRNA cis splicing, via spliceosome(GO:0045292)
0.0	0.0	GO:1902101	positive regulation of mitotic metaphase/anaphase transition(GO:0045842) positive regulation of mitotic sister chromatid separation(GO:1901970) positive regulation of metaphase/anaphase transition of cell cycle(GO:1902101)
0.0	0.0	GO:0046100	hypoxanthine metabolic process(GO:0046100)
0.0	0.0	GO:0033173	calcineurin-NFAT signaling cascade(GO:0033173)
0.0	0.0	GO:0045541	negative regulation of cholesterol biosynthetic process(GO:0045541) negative regulation of cholesterol metabolic process(GO:0090206)
0.0	0.0	GO:0060129	thyroid-stimulating hormone-secreting cell differentiation(GO:0060129)
0.0	0.0	GO:0048289	isotype switching to IgE isotypes(GO:0048289) regulation of isotype switching to IgE isotypes(GO:0048293)
0.0	0.1	GO:0046831	regulation of RNA export from nucleus(GO:0046831)
0.0	0.2	GO:0045648	positive regulation of erythrocyte differentiation(GO:0045648)
0.0	0.0	GO:0070602	centromeric sister chromatid cohesion(GO:0070601) regulation of centromeric sister chromatid cohesion(GO:0070602)
0.0	0.0	GO:0061687	detoxification of inorganic compound(GO:0061687) stress response to metal ion(GO:0097501)
0.0	0.0	GO:0051973	positive regulation of telomerase activity(GO:0051973)
0.0	0.0	GO:0001787	natural killer cell proliferation(GO:0001787)
0.0	0.0	GO:0051970	negative regulation of transmission of nerve impulse(GO:0051970)
0.0	0.1	GO:0009649	entrainment of circadian clock(GO:0009649)
0.0	0.7	GO:0060333	interferon-gamma-mediated signaling pathway(GO:0060333)
0.0	0.5	GO:0050772	positive regulation of axonogenesis(GO:0050772)
0.0	0.0	GO:0008049	male courtship behavior(GO:0008049)
0.0	0.0	GO:0042670	retinal cone cell differentiation(GO:0042670) retinal cone cell development(GO:0046549)
0.0	0.1	GO:0006477	protein sulfation(GO:0006477)
0.0	0.2	GO:0042776	mitochondrial ATP synthesis coupled proton transport(GO:0042776)
0.0	0.1	GO:0030206	chondroitin sulfate biosynthetic process(GO:0030206)
0.0	0.1	GO:0006102	isocitrate metabolic process(GO:0006102)
0.0	0.2	GO:0042771	intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator(GO:0042771)
0.0	0.1	GO:0043631	RNA polyadenylation(GO:0043631)
0.0	0.0	GO:0019532	oxalate transport(GO:0019532)
0.0	0.0	GO:0071392	cellular response to estradiol stimulus(GO:0071392)
0.0	0.1	GO:0015712	hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760)
0.0	0.0	GO:0007352	zygotic specification of dorsal/ventral axis(GO:0007352)
0.0	0.0	GO:0010832	negative regulation of myotube differentiation(GO:0010832)
0.0	0.0	GO:0006167	AMP biosynthetic process(GO:0006167)
0.0	0.1	GO:0045022	early endosome to late endosome transport(GO:0045022) vesicle-mediated transport between endosomal compartments(GO:0098927)
0.0	0.0	GO:1901374	acetylcholine transport(GO:0015870) acetate ester transport(GO:1901374)
0.0	0.1	GO:1902603	carnitine shuttle(GO:0006853) carnitine transmembrane transport(GO:1902603)
0.0	0.0	GO:0034067	protein localization to Golgi apparatus(GO:0034067)
0.0	0.3	GO:0007602	phototransduction(GO:0007602)
0.0	0.1	GO:0008105	asymmetric protein localization(GO:0008105)
0.0	0.0	GO:2000171	negative regulation of dendrite development(GO:2000171)
0.0	0.1	GO:0048024	regulation of mRNA splicing, via spliceosome(GO:0048024)
0.0	0.1	GO:0032981	NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.0	0.0	GO:0040009	regulation of growth rate(GO:0040009)
0.0	0.0	GO:1903672	regulation of cell migration involved in sprouting angiogenesis(GO:0090049) positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050) regulation of sprouting angiogenesis(GO:1903670) positive regulation of sprouting angiogenesis(GO:1903672)
0.0	0.1	GO:0010042	response to manganese ion(GO:0010042)
0.0	0.4	GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:0000184)
0.0	0.1	GO:0098657	neurotransmitter uptake(GO:0001504) import into cell(GO:0098657)
0.0	0.1	GO:0000244	spliceosomal tri-snRNP complex assembly(GO:0000244)
0.0	0.0	GO:0045835	negative regulation of meiotic nuclear division(GO:0045835)
0.0	0.2	GO:0033209	tumor necrosis factor-mediated signaling pathway(GO:0033209)
0.0	0.2	GO:0016254	preassembly of GPI anchor in ER membrane(GO:0016254)
0.0	0.0	GO:0032925	regulation of activin receptor signaling pathway(GO:0032925)
0.0	0.2	GO:0007076	mitotic chromosome condensation(GO:0007076)
0.0	0.0	GO:0015705	iodide transport(GO:0015705)
0.0	0.1	GO:0032109	positive regulation of response to extracellular stimulus(GO:0032106) positive regulation of response to nutrient levels(GO:0032109)
0.0	0.7	GO:0008360	regulation of cell shape(GO:0008360)
0.0	0.0	GO:0031935	regulation of chromatin silencing(GO:0031935)
0.0	0.0	GO:0051988	regulation of attachment of spindle microtubules to kinetochore(GO:0051988)
0.0	0.1	GO:0006704	glucocorticoid biosynthetic process(GO:0006704)
0.0	0.0	GO:0045070	positive regulation of viral genome replication(GO:0045070)
0.0	0.2	GO:0048814	regulation of dendrite morphogenesis(GO:0048814)
0.0	0.1	GO:0031103	axon regeneration(GO:0031103)
0.0	0.1	GO:0000185	activation of MAPKKK activity(GO:0000185)
0.0	0.0	GO:0034698	response to gonadotropin(GO:0034698)
0.0	0.0	GO:0033033	negative regulation of myeloid cell apoptotic process(GO:0033033)
0.0	0.1	GO:0006684	sphingomyelin metabolic process(GO:0006684)
0.0	0.0	GO:0021707	cerebellar granular layer development(GO:0021681) cerebellar granular layer morphogenesis(GO:0021683) cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707)
0.0	0.1	GO:0032456	endocytic recycling(GO:0032456)
0.0	0.1	GO:0002921	negative regulation of humoral immune response(GO:0002921) negative regulation of complement activation(GO:0045916) negative regulation of protein activation cascade(GO:2000258)
0.0	0.1	GO:0048016	inositol phosphate-mediated signaling(GO:0048016)
0.0	0.1	GO:0050908	detection of light stimulus involved in visual perception(GO:0050908) detection of light stimulus involved in sensory perception(GO:0050962)
0.0	0.2	GO:0034199	activation of protein kinase A activity(GO:0034199)
0.0	0.0	GO:0031573	intra-S DNA damage checkpoint(GO:0031573)
0.0	0.0	GO:0042921	glucocorticoid receptor signaling pathway(GO:0042921)
0.0	0.0	GO:0050765	negative regulation of phagocytosis(GO:0050765)
0.0	0.1	GO:0045814	negative regulation of gene expression, epigenetic(GO:0045814)
0.0	0.0	GO:0043320	natural killer cell activation involved in immune response(GO:0002323) natural killer cell degranulation(GO:0043320)
0.0	0.1	GO:0046519	sphingoid metabolic process(GO:0046519)
0.0	0.0	GO:0015791	polyol transport(GO:0015791)
0.0	0.0	GO:0006978	DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:0006978)
0.0	0.1	GO:0031115	negative regulation of microtubule polymerization(GO:0031115)
0.0	0.1	GO:0001510	RNA methylation(GO:0001510)
0.0	0.0	GO:0031223	auditory behavior(GO:0031223)
0.0	0.1	GO:0071482	cellular response to light stimulus(GO:0071482)
0.0	0.0	GO:0071922	establishment of sister chromatid cohesion(GO:0034085) cohesin loading(GO:0071921) regulation of cohesin loading(GO:0071922)
0.0	0.1	GO:0043628	ncRNA 3'-end processing(GO:0043628)
0.0	0.2	GO:0051607	defense response to virus(GO:0051607)
0.0	0.3	GO:0030199	collagen fibril organization(GO:0030199)
0.0	0.0	GO:0000470	maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000463) maturation of LSU-rRNA(GO:0000470)
0.0	0.0	GO:0046501	protoporphyrinogen IX metabolic process(GO:0046501)
0.0	0.0	GO:0072526	pyridine-containing compound catabolic process(GO:0072526)
0.0	0.0	GO:0033522	histone H2A ubiquitination(GO:0033522)
0.0	0.2	GO:0000289	nuclear-transcribed mRNA poly(A) tail shortening(GO:0000289)
0.0	0.1	GO:0031648	protein destabilization(GO:0031648)
0.0	0.0	GO:0052200	response to defenses of other organism involved in symbiotic interaction(GO:0052173) response to host defenses(GO:0052200) response to host(GO:0075136)
0.0	0.0	GO:0050917	sensory perception of umami taste(GO:0050917)
0.0	0.0	GO:0071294	cellular response to zinc ion(GO:0071294)
0.0	0.1	GO:0008343	adult feeding behavior(GO:0008343)
0.0	0.2	GO:0030317	sperm motility(GO:0030317)
0.0	0.0	GO:0071569	protein ufmylation(GO:0071569)
0.0	0.0	GO:0048388	endosomal lumen acidification(GO:0048388)
0.0	0.1	GO:0030212	hyaluronan metabolic process(GO:0030212)
0.0	0.0	GO:0031498	nucleosome disassembly(GO:0006337) chromatin disassembly(GO:0031498) protein-DNA complex disassembly(GO:0032986)
0.0	0.2	GO:0006904	vesicle docking involved in exocytosis(GO:0006904)
0.0	0.1	GO:0048387	negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.0	0.0	GO:0021612	cranial nerve structural organization(GO:0021604) facial nerve morphogenesis(GO:0021610) facial nerve structural organization(GO:0021612) anatomical structure arrangement(GO:0048532)
0.0	0.0	GO:0048710	regulation of astrocyte differentiation(GO:0048710)
0.0	0.1	GO:0006020	inositol metabolic process(GO:0006020)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	0.5	GO:0042105	alpha-beta T cell receptor complex(GO:0042105)
0.1	0.4	GO:0030934	anchoring collagen complex(GO:0030934)
0.1	0.3	GO:0031235	intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.1	0.7	GO:0001891	phagocytic cup(GO:0001891)
0.1	0.3	GO:0005900	oncostatin-M receptor complex(GO:0005900)
0.1	0.3	GO:0034992	microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.1	0.3	GO:0005954	calcium- and calmodulin-dependent protein kinase complex(GO:0005954)
0.1	0.3	GO:0005827	polar microtubule(GO:0005827)
0.1	0.2	GO:0072487	MSL complex(GO:0072487)
0.1	0.2	GO:0033270	paranode region of axon(GO:0033270)
0.1	0.2	GO:0032009	early phagosome(GO:0032009)
0.1	0.2	GO:0000137	Golgi cis cisterna(GO:0000137)
0.1	0.2	GO:0042629	mast cell granule(GO:0042629)
0.1	0.2	GO:0031932	TORC2 complex(GO:0031932)
0.0	0.3	GO:0072357	PTW/PP1 phosphatase complex(GO:0072357)
0.0	0.5	GO:0001772	immunological synapse(GO:0001772)
0.0	0.5	GO:0005942	phosphatidylinositol 3-kinase complex(GO:0005942)
0.0	0.5	GO:0010494	cytoplasmic stress granule(GO:0010494)
0.0	0.1	GO:0032777	Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.0	0.5	GO:0045334	clathrin-coated endocytic vesicle(GO:0045334)
0.0	0.2	GO:0044224	juxtaparanode region of axon(GO:0044224)
0.0	0.1	GO:0038201	TOR complex(GO:0038201)
0.0	0.2	GO:0000125	PCAF complex(GO:0000125)
0.0	0.3	GO:0031105	septin complex(GO:0031105) septin cytoskeleton(GO:0032156)
0.0	0.2	GO:0019907	cyclin-dependent protein kinase activating kinase holoenzyme complex(GO:0019907)
0.0	0.2	GO:0005697	telomerase holoenzyme complex(GO:0005697)
0.0	0.1	GO:0072669	tRNA-splicing ligase complex(GO:0072669)
0.0	0.1	GO:0008540	proteasome regulatory particle, base subcomplex(GO:0008540)
0.0	0.2	GO:0042598	obsolete vesicular fraction(GO:0042598)
0.0	0.3	GO:0005849	mRNA cleavage factor complex(GO:0005849)
0.0	0.1	GO:0005862	muscle thin filament tropomyosin(GO:0005862)
0.0	0.2	GO:0008290	F-actin capping protein complex(GO:0008290)
0.0	0.1	GO:0070062	extracellular exosome(GO:0070062) extracellular vesicle(GO:1903561)
0.0	0.0	GO:0000164	protein phosphatase type 1 complex(GO:0000164)
0.0	0.1	GO:0005899	insulin receptor complex(GO:0005899)
0.0	0.1	GO:0000300	obsolete peripheral to membrane of membrane fraction(GO:0000300)
0.0	0.1	GO:0070695	FHF complex(GO:0070695)
0.0	1.0	GO:0030173	integral component of Golgi membrane(GO:0030173)
0.0	0.1	GO:0071438	invadopodium membrane(GO:0071438)
0.0	0.0	GO:0071437	invadopodium(GO:0071437)
0.0	0.1	GO:0034673	inhibin-betaglycan-ActRII complex(GO:0034673)
0.0	0.1	GO:0043218	compact myelin(GO:0043218)
0.0	0.1	GO:0000276	mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.0	0.4	GO:0005892	acetylcholine-gated channel complex(GO:0005892)
0.0	0.1	GO:0019908	nuclear cyclin-dependent protein kinase holoenzyme complex(GO:0019908)
0.0	0.1	GO:0032591	dendritic spine membrane(GO:0032591)
0.0	0.1	GO:0031371	ubiquitin conjugating enzyme complex(GO:0031371)
0.0	0.1	GO:0070775	H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.0	0.1	GO:0033150	cytoskeletal calyx(GO:0033150)
0.0	0.2	GO:0045120	pronucleus(GO:0045120)
0.0	0.0	GO:0032593	insulin-responsive compartment(GO:0032593)
0.0	0.1	GO:0031254	uropod(GO:0001931) cell trailing edge(GO:0031254)
0.0	0.2	GO:0032839	dendrite cytoplasm(GO:0032839)
0.0	0.1	GO:0035189	Rb-E2F complex(GO:0035189)
0.0	0.1	GO:0005826	actomyosin contractile ring(GO:0005826)
0.0	0.1	GO:0033162	melanosome membrane(GO:0033162) chitosome(GO:0045009)
0.0	0.1	GO:0001652	granular component(GO:0001652)
0.0	0.1	GO:0031616	spindle pole centrosome(GO:0031616)
0.0	0.0	GO:0000506	glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.0	0.4	GO:0005626	obsolete insoluble fraction(GO:0005626)
0.0	0.1	GO:0071204	histone pre-mRNA 3'end processing complex(GO:0071204)
0.0	0.1	GO:0030904	retromer complex(GO:0030904)
0.0	0.4	GO:0032587	ruffle membrane(GO:0032587)
0.0	0.1	GO:0043190	ATP-binding cassette (ABC) transporter complex(GO:0043190)
0.0	0.0	GO:0032449	CBM complex(GO:0032449)
0.0	0.0	GO:0005588	collagen type V trimer(GO:0005588)
0.0	0.3	GO:0000159	protein phosphatase type 2A complex(GO:0000159)
0.0	0.1	GO:0070552	BRISC complex(GO:0070552)
0.0	0.1	GO:0033276	transcription factor TFTC complex(GO:0033276)
0.0	0.1	GO:0016342	catenin complex(GO:0016342)
0.0	0.3	GO:0034385	very-low-density lipoprotein particle(GO:0034361) triglyceride-rich lipoprotein particle(GO:0034385)
0.0	0.1	GO:0042788	polysomal ribosome(GO:0042788)
0.0	0.4	GO:0030175	filopodium(GO:0030175)
0.0	0.1	GO:0031265	CD95 death-inducing signaling complex(GO:0031265)
0.0	0.1	GO:0000275	mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275)
0.0	0.1	GO:0005797	Golgi medial cisterna(GO:0005797)
0.0	0.0	GO:0033011	perinuclear theca(GO:0033011)
0.0	0.0	GO:0033268	node of Ranvier(GO:0033268)
0.0	0.0	GO:0005927	muscle tendon junction(GO:0005927)
0.0	0.1	GO:0031010	ISWI-type complex(GO:0031010)
0.0	0.1	GO:0000796	condensin complex(GO:0000796)
0.0	0.0	GO:0046540	U4/U6 x U5 tri-snRNP complex(GO:0046540) spliceosomal tri-snRNP complex(GO:0097526)
0.0	0.0	GO:0070545	PeBoW complex(GO:0070545)
0.0	0.6	GO:0031901	early endosome membrane(GO:0031901)
0.0	0.0	GO:0071942	XPC complex(GO:0071942)
0.0	0.2	GO:0098573	intrinsic component of mitochondrial membrane(GO:0098573)
0.0	0.1	GO:0030673	axolemma(GO:0030673)
0.0	0.2	GO:0030530	obsolete heterogeneous nuclear ribonucleoprotein complex(GO:0030530)
0.0	0.1	GO:0035098	ESC/E(Z) complex(GO:0035098)
0.0	0.0	GO:0030895	apolipoprotein B mRNA editing enzyme complex(GO:0030895)
0.0	0.0	GO:0005594	collagen type IX trimer(GO:0005594)
0.0	0.1	GO:0042101	T cell receptor complex(GO:0042101)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	0.5	GO:0003836	beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.1	0.4	GO:0016309	1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
0.1	0.9	GO:0016494	C-X-C chemokine receptor activity(GO:0016494)
0.1	0.4	GO:0004911	interleukin-2 receptor activity(GO:0004911)
0.1	0.4	GO:0046935	1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.1	0.3	GO:0031628	opioid receptor binding(GO:0031628)
0.1	1.0	GO:0016493	C-C chemokine receptor activity(GO:0016493)
0.1	0.4	GO:0047238	glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity(GO:0047238)
0.1	0.3	GO:0030368	interleukin-17 receptor activity(GO:0030368)
0.1	0.3	GO:0008454	alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.1	0.2	GO:0008321	Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.1	0.3	GO:0030284	estrogen receptor activity(GO:0030284)
0.1	0.3	GO:0015925	galactosidase activity(GO:0015925)
0.1	0.2	GO:0035197	siRNA binding(GO:0035197)
0.1	0.1	GO:0000268	peroxisome targeting sequence binding(GO:0000268)
0.1	0.2	GO:0004677	DNA-dependent protein kinase activity(GO:0004677)
0.1	0.2	GO:0033691	sialic acid binding(GO:0033691)
0.1	0.4	GO:0004691	cAMP-dependent protein kinase activity(GO:0004691)
0.1	0.4	GO:0030020	extracellular matrix structural constituent conferring tensile strength(GO:0030020)
0.1	0.2	GO:0035184	histone threonine kinase activity(GO:0035184)
0.1	0.2	GO:0004774	succinate-CoA ligase activity(GO:0004774)
0.1	0.2	GO:0008174	mRNA methyltransferase activity(GO:0008174)
0.1	0.2	GO:0015204	urea transmembrane transporter activity(GO:0015204)
0.1	0.2	GO:0030375	thyroid hormone receptor coactivator activity(GO:0030375)
0.1	0.2	GO:0050815	phosphoserine binding(GO:0050815)
0.1	0.2	GO:0004311	farnesyltranstransferase activity(GO:0004311)
0.1	0.2	GO:0008420	CTD phosphatase activity(GO:0008420)
0.1	0.3	GO:0005131	growth hormone receptor binding(GO:0005131)
0.1	0.4	GO:0005522	profilin binding(GO:0005522)
0.0	0.4	GO:0030332	cyclin binding(GO:0030332)
0.0	0.1	GO:0043175	RNA polymerase core enzyme binding(GO:0043175)
0.0	0.6	GO:0005095	GTPase inhibitor activity(GO:0005095)
0.0	0.1	GO:0004591	oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591)
0.0	0.1	GO:0042156	obsolete zinc-mediated transcriptional activator activity(GO:0042156)
0.0	1.7	GO:0004715	non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.0	0.7	GO:0030159	receptor signaling complex scaffold activity(GO:0030159)
0.0	0.1	GO:0003726	double-stranded RNA adenosine deaminase activity(GO:0003726)
0.0	0.9	GO:0005164	tumor necrosis factor receptor binding(GO:0005164)
0.0	0.2	GO:0001637	G-protein coupled chemoattractant receptor activity(GO:0001637) chemokine receptor activity(GO:0004950)
0.0	0.3	GO:0008440	inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440) inositol trisphosphate kinase activity(GO:0051766)
0.0	0.4	GO:0034593	phosphatidylinositol bisphosphate phosphatase activity(GO:0034593)
0.0	0.5	GO:0004697	protein kinase C activity(GO:0004697)
0.0	0.5	GO:0005031	tumor necrosis factor-activated receptor activity(GO:0005031)
0.0	1.0	GO:0045028	G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.0	0.1	GO:0004566	beta-glucuronidase activity(GO:0004566)
0.0	0.2	GO:0043539	protein serine/threonine kinase activator activity(GO:0043539)
0.0	0.3	GO:0015271	outward rectifier potassium channel activity(GO:0015271)
0.0	0.1	GO:0070735	protein-glycine ligase activity(GO:0070735)
0.0	0.2	GO:0005381	iron ion transmembrane transporter activity(GO:0005381)
0.0	0.2	GO:0004694	eukaryotic translation initiation factor 2alpha kinase activity(GO:0004694)
0.0	0.2	GO:0061630	ubiquitin-ubiquitin ligase activity(GO:0034450) ubiquitin protein ligase activity(GO:0061630) ubiquitin-like protein ligase activity(GO:0061659)
0.0	0.4	GO:0051018	protein kinase A binding(GO:0051018)
0.0	0.1	GO:0003909	DNA ligase activity(GO:0003909) DNA ligase (ATP) activity(GO:0003910)
0.0	0.1	GO:0032454	histone demethylase activity (H3-K9 specific)(GO:0032454)
0.0	0.2	GO:0004706	JUN kinase kinase kinase activity(GO:0004706)
0.0	0.1	GO:0001609	G-protein coupled adenosine receptor activity(GO:0001609)
0.0	0.3	GO:0004568	chitinase activity(GO:0004568)
0.0	0.1	GO:0001591	dopamine neurotransmitter receptor activity, coupled via Gi/Go(GO:0001591)
0.0	0.1	GO:0070097	delta-catenin binding(GO:0070097)
0.0	0.2	GO:0004957	prostaglandin E receptor activity(GO:0004957)
0.0	0.2	GO:0052813	phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) phosphatidylinositol bisphosphate kinase activity(GO:0052813)
0.0	0.1	GO:0005134	interleukin-2 receptor binding(GO:0005134)
0.0	0.3	GO:0004571	mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.0	0.1	GO:0016842	amidine-lyase activity(GO:0016842)
0.0	0.1	GO:0005350	pyrimidine nucleobase transmembrane transporter activity(GO:0005350)
0.0	0.1	GO:0005113	patched binding(GO:0005113)
0.0	0.2	GO:0016857	racemase and epimerase activity, acting on carbohydrates and derivatives(GO:0016857)
0.0	0.2	GO:0030346	protein phosphatase 2B binding(GO:0030346)
0.0	0.0	GO:0032139	dinucleotide insertion or deletion binding(GO:0032139)
0.0	0.3	GO:0015385	sodium:proton antiporter activity(GO:0015385)
0.0	0.1	GO:0005275	amine transmembrane transporter activity(GO:0005275)
0.0	0.0	GO:0004687	myosin light chain kinase activity(GO:0004687)
0.0	0.1	GO:0004740	pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.0	0.1	GO:0034713	type I transforming growth factor beta receptor binding(GO:0034713)
0.0	0.1	GO:0004167	dopachrome isomerase activity(GO:0004167)
0.0	0.1	GO:0003886	DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.0	0.1	GO:0004307	ethanolaminephosphotransferase activity(GO:0004307)
0.0	0.1	GO:0005094	Rho GDP-dissociation inhibitor activity(GO:0005094)
0.0	0.2	GO:0070410	co-SMAD binding(GO:0070410)
0.0	0.1	GO:0033300	dehydroascorbic acid transporter activity(GO:0033300)
0.0	1.4	GO:0005070	SH3/SH2 adaptor activity(GO:0005070)
0.0	0.1	GO:0070653	high-density lipoprotein particle receptor binding(GO:0070653)
0.0	0.1	GO:0003985	acetyl-CoA C-acetyltransferase activity(GO:0003985)
0.0	0.4	GO:0031593	polyubiquitin binding(GO:0031593)
0.0	0.1	GO:0005176	ErbB-2 class receptor binding(GO:0005176)
0.0	0.1	GO:0005521	lamin binding(GO:0005521)
0.0	0.2	GO:0045309	protein phosphorylated amino acid binding(GO:0045309)
0.0	0.1	GO:0003953	NAD+ nucleosidase activity(GO:0003953)
0.0	0.1	GO:0004815	aspartate-tRNA ligase activity(GO:0004815)
0.0	0.2	GO:0003747	translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079)
0.0	0.1	GO:0004563	beta-N-acetylhexosaminidase activity(GO:0004563)
0.0	0.3	GO:0034739	histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041) histone deacetylase activity (H4-K16 specific)(GO:0034739) NAD-dependent histone deacetylase activity (H4-K16 specific)(GO:0046970)
0.0	0.1	GO:0046975	histone methyltransferase activity (H3-K36 specific)(GO:0046975)
0.0	0.1	GO:0008607	phosphorylase kinase regulator activity(GO:0008607)
0.0	0.1	GO:0016941	natriuretic peptide receptor activity(GO:0016941)
0.0	0.1	GO:0003829	beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity(GO:0003829)
0.0	0.1	GO:0005068	transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.0	0.3	GO:0043425	bHLH transcription factor binding(GO:0043425)
0.0	0.0	GO:0015421	oligopeptide-transporting ATPase activity(GO:0015421) peptide-transporting ATPase activity(GO:0015440)
0.0	0.1	GO:0005314	high-affinity glutamate transmembrane transporter activity(GO:0005314)
0.0	0.1	GO:0030881	beta-2-microglobulin binding(GO:0030881)
0.0	0.2	GO:0051879	Hsp90 protein binding(GO:0051879)
0.0	0.1	GO:0015288	porin activity(GO:0015288)
0.0	0.2	GO:0099604	calcium-release channel activity(GO:0015278) ligand-gated calcium channel activity(GO:0099604)
0.0	0.1	GO:0015333	peptide:proton symporter activity(GO:0015333) proton-dependent peptide secondary active transmembrane transporter activity(GO:0022897)
0.0	0.0	GO:0000400	four-way junction DNA binding(GO:0000400)
0.0	0.0	GO:0050698	proteoglycan sulfotransferase activity(GO:0050698)
0.0	0.1	GO:0070215	obsolete MDM2 binding(GO:0070215)
0.0	0.1	GO:0004802	transketolase activity(GO:0004802)
0.0	0.4	GO:0004683	calmodulin-dependent protein kinase activity(GO:0004683)
0.0	0.1	GO:0070577	lysine-acetylated histone binding(GO:0070577)
0.0	0.4	GO:0045296	cadherin binding(GO:0045296)
0.0	0.1	GO:0008510	sodium:bicarbonate symporter activity(GO:0008510)
0.0	0.2	GO:0004767	sphingomyelin phosphodiesterase activity(GO:0004767)
0.0	0.1	GO:0043141	ATP-dependent 5'-3' DNA helicase activity(GO:0043141)
0.0	0.1	GO:0032794	GTPase activating protein binding(GO:0032794)
0.0	0.5	GO:0003950	NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.0	0.1	GO:0016748	succinyltransferase activity(GO:0016748)
0.0	0.1	GO:0004000	adenosine deaminase activity(GO:0004000)
0.0	0.1	GO:0017056	structural constituent of nuclear pore(GO:0017056)
0.0	0.1	GO:0008296	3'-5'-exodeoxyribonuclease activity(GO:0008296)
0.0	0.1	GO:0043008	ATP-dependent protein binding(GO:0043008)
0.0	0.1	GO:0042043	neurexin family protein binding(GO:0042043)
0.0	0.1	GO:0004596	peptide alpha-N-acetyltransferase activity(GO:0004596)
0.0	0.4	GO:0008484	sulfuric ester hydrolase activity(GO:0008484)
0.0	0.3	GO:0019198	transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.0	0.1	GO:0015252	hydrogen ion channel activity(GO:0015252)
0.0	0.1	GO:0047631	ADP-ribose diphosphatase activity(GO:0047631)
0.0	0.1	GO:0097493	extracellular matrix constituent conferring elasticity(GO:0030023) structural molecule activity conferring elasticity(GO:0097493)
0.0	0.1	GO:0034481	chondroitin sulfotransferase activity(GO:0034481)
0.0	0.1	GO:0008494	translation activator activity(GO:0008494)
0.0	0.1	GO:0030292	protein tyrosine kinase inhibitor activity(GO:0030292)
0.0	0.1	GO:0004169	dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.0	0.1	GO:0008649	rRNA methyltransferase activity(GO:0008649)
0.0	0.1	GO:0032137	guanine/thymine mispair binding(GO:0032137)
0.0	0.1	GO:0004449	isocitrate dehydrogenase (NAD+) activity(GO:0004449)
0.0	0.2	GO:0004602	glutathione peroxidase activity(GO:0004602)
0.0	0.1	GO:0055106	ligase regulator activity(GO:0055103) ubiquitin-protein transferase regulator activity(GO:0055106)
0.0	0.1	GO:0008140	cAMP response element binding protein binding(GO:0008140)
0.0	0.1	GO:0034187	obsolete apolipoprotein E binding(GO:0034187)
0.0	0.1	GO:0017128	phospholipid scramblase activity(GO:0017128)
0.0	0.1	GO:0004946	bombesin receptor activity(GO:0004946)
0.0	0.1	GO:0004607	phosphatidylcholine-sterol O-acyltransferase activity(GO:0004607)
0.0	0.1	GO:0008574	ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574) ATP-dependent microtubule motor activity(GO:1990939)
0.0	0.1	GO:0042392	sphingosine-1-phosphate phosphatase activity(GO:0042392)
0.0	0.0	GO:0017162	aryl hydrocarbon receptor binding(GO:0017162)
0.0	0.1	GO:0016922	ligand-dependent nuclear receptor binding(GO:0016922)
0.0	0.1	GO:0008184	glycogen phosphorylase activity(GO:0008184)
0.0	0.1	GO:0043184	vascular endothelial growth factor receptor 2 binding(GO:0043184)
0.0	0.1	GO:0008253	5'-nucleotidase activity(GO:0008253)
0.0	0.1	GO:0016778	diphosphotransferase activity(GO:0016778)
0.0	0.1	GO:0019166	trans-2-enoyl-CoA reductase (NADPH) activity(GO:0019166)
0.0	0.1	GO:0004862	cAMP-dependent protein kinase inhibitor activity(GO:0004862)
0.0	0.2	GO:0042162	telomeric DNA binding(GO:0042162)
0.0	0.1	GO:0036137	kynurenine-oxoglutarate transaminase activity(GO:0016212) kynurenine aminotransferase activity(GO:0036137)
0.0	0.2	GO:0042166	acetylcholine binding(GO:0042166)
0.0	0.1	GO:0019911	structural constituent of myelin sheath(GO:0019911)
0.0	0.3	GO:0008601	protein phosphatase type 2A regulator activity(GO:0008601)
0.0	0.5	GO:0003823	antigen binding(GO:0003823)
0.0	0.4	GO:0003746	translation elongation factor activity(GO:0003746)
0.0	0.1	GO:0000064	L-ornithine transmembrane transporter activity(GO:0000064)
0.0	0.1	GO:0004095	carnitine O-palmitoyltransferase activity(GO:0004095) O-palmitoyltransferase activity(GO:0016416)
0.0	0.0	GO:0070548	L-glutamine aminotransferase activity(GO:0070548)
0.0	0.1	GO:0008568	microtubule-severing ATPase activity(GO:0008568)
0.0	0.0	GO:0031849	olfactory receptor binding(GO:0031849)
0.0	1.0	GO:0004221	obsolete ubiquitin thiolesterase activity(GO:0004221)
0.0	0.1	GO:0016847	1-aminocyclopropane-1-carboxylate synthase activity(GO:0016847)
0.0	0.0	GO:0017159	pantetheine hydrolase activity(GO:0017159)
0.0	0.0	GO:0010861	thyroid hormone receptor activator activity(GO:0010861)
0.0	0.0	GO:0004949	cannabinoid receptor activity(GO:0004949)
0.0	0.0	GO:0030976	thiamine pyrophosphate binding(GO:0030976)
0.0	0.0	GO:0061731	ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
0.0	0.1	GO:0035252	UDP-xylosyltransferase activity(GO:0035252) xylosyltransferase activity(GO:0042285)
0.0	0.0	GO:0005049	nuclear export signal receptor activity(GO:0005049)
0.0	0.0	GO:0070492	oligosaccharide binding(GO:0070492)
0.0	0.0	GO:0030229	very-low-density lipoprotein particle receptor activity(GO:0030229)
0.0	0.4	GO:0001104	RNA polymerase II transcription cofactor activity(GO:0001104)
0.0	0.1	GO:0004652	polynucleotide adenylyltransferase activity(GO:0004652)
0.0	0.1	GO:0046974	histone methyltransferase activity (H3-K9 specific)(GO:0046974)
0.0	0.1	GO:0016934	extracellular-glycine-gated ion channel activity(GO:0016933) extracellular-glycine-gated chloride channel activity(GO:0016934)
0.0	0.1	GO:0015057	thrombin receptor activity(GO:0015057)
0.0	0.4	GO:0004402	histone acetyltransferase activity(GO:0004402)
0.0	0.0	GO:0030354	melanin-concentrating hormone activity(GO:0030354)
0.0	0.5	GO:0017048	Rho GTPase binding(GO:0017048)
0.0	0.0	GO:0019531	oxalate transmembrane transporter activity(GO:0019531)
0.0	0.1	GO:0017110	nucleoside-diphosphatase activity(GO:0017110)
0.0	0.1	GO:0047429	nucleoside-triphosphate diphosphatase activity(GO:0047429)
0.0	0.0	GO:0004938	alpha2-adrenergic receptor activity(GO:0004938)
0.0	0.1	GO:0004889	acetylcholine-activated cation-selective channel activity(GO:0004889)
0.0	0.3	GO:0003724	RNA helicase activity(GO:0003724)
0.0	0.0	GO:0008332	low voltage-gated calcium channel activity(GO:0008332)
0.0	0.0	GO:0050510	N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity(GO:0050510)
0.0	0.1	GO:0004616	phosphogluconate dehydrogenase (decarboxylating) activity(GO:0004616)
0.0	0.2	GO:0005540	hyaluronic acid binding(GO:0005540)
0.0	0.1	GO:0016997	exo-alpha-sialidase activity(GO:0004308) alpha-sialidase activity(GO:0016997)
0.0	0.0	GO:0004966	galanin receptor activity(GO:0004966)
0.0	0.0	GO:0004597	peptide-aspartate beta-dioxygenase activity(GO:0004597)
0.0	0.1	GO:0031210	phosphatidylcholine binding(GO:0031210)
0.0	0.0	GO:0061133	endopeptidase activator activity(GO:0061133)
0.0	0.0	GO:0016520	growth hormone-releasing hormone receptor activity(GO:0016520)
0.0	0.0	GO:0008853	exodeoxyribonuclease III activity(GO:0008853)
0.0	0.0	GO:0033765	steroid dehydrogenase activity, acting on the CH-CH group of donors(GO:0033765)
0.0	0.1	GO:0017075	syntaxin-1 binding(GO:0017075)
0.0	0.0	GO:0016314	phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity(GO:0016314)
0.0	0.1	GO:0008526	phosphatidylinositol transporter activity(GO:0008526)
0.0	0.0	GO:0050682	AF-2 domain binding(GO:0050682)
0.0	0.1	GO:0004726	non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.0	0.9	GO:0017124	SH3 domain binding(GO:0017124)
0.0	0.1	GO:0016500	protein-hormone receptor activity(GO:0016500)
0.0	0.1	GO:0016889	endodeoxyribonuclease activity, producing 3'-phosphomonoesters(GO:0016889)
0.0	0.0	GO:0008242	omega peptidase activity(GO:0008242)
0.0	0.1	GO:0008239	dipeptidyl-peptidase activity(GO:0008239)
0.0	0.0	GO:0019870	potassium channel inhibitor activity(GO:0019870)
0.0	0.2	GO:0005246	calcium channel regulator activity(GO:0005246)
0.0	0.0	GO:0034711	inhibin binding(GO:0034711)
0.0	0.1	GO:0016018	cyclosporin A binding(GO:0016018)
0.0	0.1	GO:0070087	chromo shadow domain binding(GO:0070087)
0.0	0.1	GO:0043395	heparan sulfate proteoglycan binding(GO:0043395)
0.0	0.1	GO:0016421	CoA carboxylase activity(GO:0016421)
0.0	0.0	GO:0050694	galactosylceramide sulfotransferase activity(GO:0001733) galactose 3-O-sulfotransferase activity(GO:0050694)
0.0	0.0	GO:0016774	phosphotransferase activity, carboxyl group as acceptor(GO:0016774)
0.0	0.1	GO:0004459	L-lactate dehydrogenase activity(GO:0004459)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	2.2	PID ECADHERIN KERATINOCYTE PATHWAY	E-cadherin signaling in keratinocytes
0.1	3.6	PID CD8 TCR PATHWAY	TCR signaling in naïve CD8+ T cells
0.1	0.9	SA MMP CYTOKINE CONNECTION	Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.1	1.2	PID IL2 STAT5 PATHWAY	IL2 signaling events mediated by STAT5
0.1	1.0	PID TCR PATHWAY	TCR signaling in naïve CD4+ T cells
0.1	1.6	PID ERBB1 INTERNALIZATION PATHWAY	Internalization of ErbB1
0.0	0.2	PID TXA2PATHWAY	Thromboxane A2 receptor signaling
0.0	0.3	SA PTEN PATHWAY	PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.0	1.5	PID NFAT 3PATHWAY	Role of Calcineurin-dependent NFAT signaling in lymphocytes
0.0	0.2	ST PAC1 RECEPTOR PATHWAY	PAC1 Receptor Pathway
0.0	0.7	PID REELIN PATHWAY	Reelin signaling pathway
0.0	0.1	PID LPA4 PATHWAY	LPA4-mediated signaling events
0.0	0.5	PID S1P S1P3 PATHWAY	S1P3 pathway
0.0	0.8	PID CDC42 REG PATHWAY	Regulation of CDC42 activity
0.0	0.5	PID IL27 PATHWAY	IL27-mediated signaling events
0.0	1.0	PID NFAT TFPATHWAY	Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0	0.3	PID NFKAPPAB CANONICAL PATHWAY	Canonical NF-kappaB pathway
0.0	0.5	PID IFNG PATHWAY	IFN-gamma pathway
0.0	0.6	PID MYC PATHWAY	C-MYC pathway
0.0	0.3	PID INSULIN GLUCOSE PATHWAY	Insulin-mediated glucose transport
0.0	0.3	PID THROMBIN PAR1 PATHWAY	PAR1-mediated thrombin signaling events
0.0	0.0	PID ERBB NETWORK PATHWAY	ErbB receptor signaling network
0.0	0.4	PID ARF 3PATHWAY	Arf1 pathway
0.0	0.5	PID ECADHERIN NASCENT AJ PATHWAY	E-cadherin signaling in the nascent adherens junction
0.0	0.7	PID TNF PATHWAY	TNF receptor signaling pathway
0.0	0.1	ST DIFFERENTIATION PATHWAY IN PC12 CELLS	Differentiation Pathway in PC12 Cells; this is a specific case of PAC1 Receptor Pathway.
0.0	0.3	PID THROMBIN PAR4 PATHWAY	PAR4-mediated thrombin signaling events
0.0	0.1	ST ERK1 ERK2 MAPK PATHWAY	ERK1/ERK2 MAPK Pathway
0.0	0.2	PID BCR 5PATHWAY	BCR signaling pathway
0.0	0.1	PID SYNDECAN 3 PATHWAY	Syndecan-3-mediated signaling events
0.0	0.2	PID RAC1 REG PATHWAY	Regulation of RAC1 activity
0.0	0.3	PID RAS PATHWAY	Regulation of Ras family activation
0.0	0.1	ST TUMOR NECROSIS FACTOR PATHWAY	Tumor Necrosis Factor Pathway.
0.0	0.1	PID P38 ALPHA BETA PATHWAY	Regulation of p38-alpha and p38-beta
0.0	0.0	SIG IL4RECEPTOR IN B LYPHOCYTES	Genes related to IL4 rceptor signaling in B lymphocytes
0.0	0.2	SA CASPASE CASCADE	Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.0	0.0	PID EPO PATHWAY	EPO signaling pathway
0.0	0.1	ST JNK MAPK PATHWAY	JNK MAPK Pathway
0.0	0.2	PID ERB GENOMIC PATHWAY	Validated nuclear estrogen receptor beta network
0.0	0.1	PID P38 GAMMA DELTA PATHWAY	Signaling mediated by p38-gamma and p38-delta
0.0	0.4	PID PS1 PATHWAY	Presenilin action in Notch and Wnt signaling
0.0	0.5	PID HNF3B PATHWAY	FOXA2 and FOXA3 transcription factor networks
0.0	0.1	PID PI3KCI PATHWAY	Class I PI3K signaling events
0.0	0.5	PID AURORA B PATHWAY	Aurora B signaling
0.0	0.0	PID IL5 PATHWAY	IL5-mediated signaling events
0.0	0.3	PID INTEGRIN A4B1 PATHWAY	Alpha4 beta1 integrin signaling events
0.0	0.2	PID IL12 2PATHWAY	IL12-mediated signaling events
0.0	0.5	NABA COLLAGENS	Genes encoding collagen proteins
0.0	0.3	PID CONE PATHWAY	Visual signal transduction: Cones
0.0	0.2	PID CERAMIDE PATHWAY	Ceramide signaling pathway
0.0	0.1	PID PDGFRB PATHWAY	PDGFR-beta signaling pathway
0.0	0.0	PID IL2 1PATHWAY	IL2-mediated signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	1.7	REACTOME PECAM1 INTERACTIONS	Genes involved in PECAM1 interactions
0.2	0.7	REACTOME BINDING AND ENTRY OF HIV VIRION	Genes involved in Binding and entry of HIV virion
0.1	1.5	REACTOME GENERATION OF SECOND MESSENGER MOLECULES	Genes involved in Generation of second messenger molecules
0.1	1.4	REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS	Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.1	1.1	REACTOME IL 7 SIGNALING	Genes involved in Interleukin-7 signaling
0.1	1.2	REACTOME N GLYCAN ANTENNAE ELONGATION	Genes involved in N-Glycan antennae elongation
0.1	0.7	REACTOME NOTCH HLH TRANSCRIPTION PATHWAY	Genes involved in Notch-HLH transcription pathway
0.1	0.4	REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS	Genes involved in Elevation of cytosolic Ca2+ levels
0.1	0.5	REACTOME ACTIVATION OF RAC	Genes involved in Activation of Rac
0.1	0.8	REACTOME RAP1 SIGNALLING	Genes involved in Rap1 signalling
0.0	0.5	REACTOME HYALURONAN UPTAKE AND DEGRADATION	Genes involved in Hyaluronan uptake and degradation
0.0	0.2	REACTOME IRAK1 RECRUITS IKK COMPLEX	Genes involved in IRAK1 recruits IKK complex
0.0	0.3	REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING	Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
0.0	0.0	REACTOME PROSTACYCLIN SIGNALLING THROUGH PROSTACYCLIN RECEPTOR	Genes involved in Prostacyclin signalling through prostacyclin receptor
0.0	0.2	REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY	Genes involved in Regulation of the Fanconi anemia pathway
0.0	0.3	REACTOME PROSTANOID LIGAND RECEPTORS	Genes involved in Prostanoid ligand receptors
0.0	0.9	REACTOME EGFR DOWNREGULATION	Genes involved in EGFR downregulation
0.0	0.3	REACTOME IL 6 SIGNALING	Genes involved in Interleukin-6 signaling
0.0	0.5	REACTOME CTNNB1 PHOSPHORYLATION CASCADE	Genes involved in Beta-catenin phosphorylation cascade
0.0	0.6	REACTOME IL RECEPTOR SHC SIGNALING	Genes involved in Interleukin receptor SHC signaling
0.0	0.7	REACTOME COSTIMULATION BY THE CD28 FAMILY	Genes involved in Costimulation by the CD28 family
0.0	0.6	REACTOME DOWNSTREAM TCR SIGNALING	Genes involved in Downstream TCR signaling
0.0	0.9	REACTOME SEMA4D IN SEMAPHORIN SIGNALING	Genes involved in Sema4D in semaphorin signaling
0.0	0.4	REACTOME PROCESSING OF INTRONLESS PRE MRNAS	Genes involved in Processing of Intronless Pre-mRNAs
0.0	0.1	REACTOME N GLYCAN ANTENNAE ELONGATION IN THE MEDIAL TRANS GOLGI	Genes involved in N-glycan antennae elongation in the medial/trans-Golgi
0.0	0.7	REACTOME RORA ACTIVATES CIRCADIAN EXPRESSION	Genes involved in RORA Activates Circadian Expression
0.0	0.2	REACTOME ENDOSOMAL VACUOLAR PATHWAY	Genes involved in Endosomal/Vacuolar pathway
0.0	0.5	REACTOME CHONDROITIN SULFATE BIOSYNTHESIS	Genes involved in Chondroitin sulfate biosynthesis
0.0	0.6	REACTOME KERATAN SULFATE KERATIN METABOLISM	Genes involved in Keratan sulfate/keratin metabolism
0.0	0.3	REACTOME PRE NOTCH TRANSCRIPTION AND TRANSLATION	Genes involved in Pre-NOTCH Transcription and Translation
0.0	0.1	REACTOME REGULATION OF INSULIN SECRETION BY GLUCAGON LIKE PEPTIDE1	Genes involved in Regulation of Insulin Secretion by Glucagon-like Peptide-1
0.0	0.3	REACTOME HIGHLY CALCIUM PERMEABLE POSTSYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS	Genes involved in Highly calcium permeable postsynaptic nicotinic acetylcholine receptors
0.0	0.0	REACTOME MRNA CAPPING	Genes involved in mRNA Capping
0.0	0.1	REACTOME G PROTEIN ACTIVATION	Genes involved in G-protein activation
0.0	1.1	REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL	Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0	0.8	REACTOME INTERFERON GAMMA SIGNALING	Genes involved in Interferon gamma signaling
0.0	0.1	REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS	Genes involved in Signal regulatory protein (SIRP) family interactions
0.0	0.3	REACTOME NUCLEOTIDE LIKE PURINERGIC RECEPTORS	Genes involved in Nucleotide-like (purinergic) receptors
0.0	0.0	REACTOME DESTABILIZATION OF MRNA BY BRF1	Genes involved in Destabilization of mRNA by Butyrate Response Factor 1 (BRF1)
0.0	0.1	REACTOME PKA MEDIATED PHOSPHORYLATION OF CREB	Genes involved in PKA-mediated phosphorylation of CREB
0.0	0.2	REACTOME ASSOCIATION OF LICENSING FACTORS WITH THE PRE REPLICATIVE COMPLEX	Genes involved in Association of licensing factors with the pre-replicative complex
0.0	0.4	REACTOME G ALPHA Z SIGNALLING EVENTS	Genes involved in G alpha (z) signalling events
0.0	0.2	REACTOME SYNTHESIS OF PE	Genes involved in Synthesis of PE
0.0	0.0	REACTOME PLATELET CALCIUM HOMEOSTASIS	Genes involved in Platelet calcium homeostasis
0.0	0.1	REACTOME ABORTIVE ELONGATION OF HIV1 TRANSCRIPT IN THE ABSENCE OF TAT	Genes involved in Abortive elongation of HIV-1 transcript in the absence of Tat
0.0	0.3	REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS	Genes involved in ABCA transporters in lipid homeostasis
0.0	0.3	REACTOME G BETA GAMMA SIGNALLING THROUGH PI3KGAMMA	Genes involved in G beta:gamma signalling through PI3Kgamma
0.0	0.2	REACTOME P38MAPK EVENTS	Genes involved in p38MAPK events
0.0	0.0	REACTOME REGULATION OF GLUCOKINASE BY GLUCOKINASE REGULATORY PROTEIN	Genes involved in Regulation of Glucokinase by Glucokinase Regulatory Protein
0.0	0.0	REACTOME AUTODEGRADATION OF THE E3 UBIQUITIN LIGASE COP1	Genes involved in Autodegradation of the E3 ubiquitin ligase COP1
0.0	0.5	REACTOME GLYCOSPHINGOLIPID METABOLISM	Genes involved in Glycosphingolipid metabolism
0.0	0.0	REACTOME VIF MEDIATED DEGRADATION OF APOBEC3G	Genes involved in Vif-mediated degradation of APOBEC3G
0.0	0.2	REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING	Genes involved in Formation of ATP by chemiosmotic coupling
0.0	0.2	REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP	Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.0	0.2	REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION	Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.0	0.1	REACTOME DAG AND IP3 SIGNALING	Genes involved in DAG and IP3 signaling
0.0	0.1	REACTOME MRNA PROCESSING	Genes involved in mRNA Processing
0.0	0.2	REACTOME REGULATION OF AMPK ACTIVITY VIA LKB1	Genes involved in Regulation of AMPK activity via LKB1
0.0	0.1	REACTOME PROLONGED ERK ACTIVATION EVENTS	Genes involved in Prolonged ERK activation events
0.0	0.1	REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT	Genes involved in Chylomicron-mediated lipid transport
0.0	0.5	REACTOME PYRUVATE METABOLISM AND CITRIC ACID TCA CYCLE	Genes involved in Pyruvate metabolism and Citric Acid (TCA) cycle
0.0	0.0	REACTOME INSULIN RECEPTOR RECYCLING	Genes involved in Insulin receptor recycling
0.0	0.2	REACTOME G0 AND EARLY G1	Genes involved in G0 and Early G1
0.0	0.0	REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION	Genes involved in activated TAK1 mediates p38 MAPK activation
0.0	0.2	REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI	Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.0	0.0	REACTOME RIP MEDIATED NFKB ACTIVATION VIA DAI	Genes involved in RIP-mediated NFkB activation via DAI
0.0	0.2	REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION	Genes involved in NOTCH1 Intracellular Domain Regulates Transcription

Results for PGR

Z-value: 2.57

Motif logo

Transcription factors associated with PGR

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

Activity of the PGR motif across conditions

Conditions sorted by the z-value of the PGR motif activity

Top target CREs of the motif:

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of PGR

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category:

Gene overrepresentation in curated gene sets: canonical pathways category:

Gene overrepresentation in curated gene sets: REACTOME pathways category: