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ENCODE: H3K4me1 ChIP-Seq of primary human cells

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Results for PKNOX1_TGIF2

Z-value: 1.00

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Transcription factors associated with PKNOX1_TGIF2

Gene Symbol	Gene ID	Gene Info
PKNOX1 Ensembl NCBI GeneCards UniProt	ENSG00000160199.10	PBX/knotted 1 homeobox 1
TGIF2 Ensembl NCBI GeneCards UniProt	ENSG00000118707.5	TGFB induced factor homeobox 2

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE	Gene	Distance	Association probability	Pearson corr. coef.	P-value	Plot
chr21_44412279_44412430	PKNOX1	17603	0.155930	-0.63	6.7e-02	Click!
chr21_44421123_44421487	PKNOX1	26554	0.141687	-0.43	2.5e-01	Click!
chr21_44395711_44396019	PKNOX1	1114	0.463398	0.42	2.6e-01	Click!
chr21_44410364_44410660	PKNOX1	15761	0.158405	0.38	3.2e-01	Click!
chr21_44412803_44413092	PKNOX1	18196	0.155104	-0.36	3.4e-01	Click!
chr20_35209812_35209963	TGIF2	2559	0.178277	0.71	3.3e-02	Click!
chr20_35210895_35211046	TGIF2	3642	0.147172	0.69	4.0e-02	Click!
chr20_35218845_35218996	TGIF2	11592	0.112747	0.60	8.9e-02	Click!
chr20_35211206_35211357	TGIF2	3953	0.142319	0.59	9.3e-02	Click!
chr20_35210615_35210766	TGIF2	3362	0.152640	0.57	1.1e-01	Click!

Activity of the PKNOX1_TGIF2 motif across conditions

Conditions sorted by the z-value of the PKNOX1_TGIF2 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE)	Target Score	Top associated gene	Gene Info	Distance of CRE to TSS	CRE/Gene association probability
chr2_65258054_65258356	0.43	AC007386.4		6426	0.18
chr10_76672520_76672974	0.42	KAT6B	K(lysine) acetyltransferase 6B	74289	0.1
chr1_145928317_145928496	0.41	PDZK1P1	PDZ domain containing 1 pseudogene 1	11707	0.16
chr15_81583881_81584196	0.41	IL16	interleukin 16	5216	0.23
chr5_150591857_150592074	0.37	GM2A	GM2 ganglioside activator	254	0.92
chr4_153024572_153024833	0.37	ENSG00000266244	.	124918	0.05
chr1_111180656_111180873	0.34	KCNA2	potassium voltage-gated channel, shaker-related subfamily, member 2	6668	0.19
chr20_43995793_43996030	0.34	SYS1	SYS1 Golgi-localized integral membrane protein homolog (S. cerevisiae)	3817	0.14
chr19_16478953_16479699	0.33	EPS15L1	epidermal growth factor receptor pathway substrate 15-like 1	6562	0.16
chr5_66475807_66475958	0.33	CD180	CD180 molecule	16745	0.25
chr1_24851664_24851815	0.33	ENSG00000266551	.	4465	0.19
chr1_25884684_25884897	0.33	LDLRAP1	low density lipoprotein receptor adaptor protein 1	14719	0.2
chr11_63311224_63311375	0.32	RARRES3	retinoic acid receptor responder (tazarotene induced) 3	5431	0.16
chrX_20158597_20158806	0.32	EIF1AX-AS1	EIF1AX antisense RNA 1	615	0.55
chr8_129557036_129557193	0.32	ENSG00000221351	.	274926	0.01
chr9_20373431_20373643	0.32	MLLT3	myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3	8930	0.21
chr4_90166750_90166901	0.31	GPRIN3	GPRIN family member 3	5520	0.31
chr7_130787419_130787695	0.31	LINC-PINT	long intergenic non-protein coding RNA, p53 induced transcript	4232	0.24
chr8_52797755_52797906	0.31	RP11-110G21.2		11104	0.18
chr1_156806225_156806376	0.29	SH2D2A	SH2 domain containing 2A	19646	0.11
chr3_16341198_16341417	0.29	RP11-415F23.2		14639	0.16
chr14_99719019_99719201	0.29	AL109767.1		10175	0.22
chr15_38826687_38826977	0.29	ENSG00000201509	.	7612	0.17
chr22_36685523_36685910	0.28	ENSG00000266345	.	26530	0.15
chr3_192632519_192632670	0.28	MB21D2	Mab-21 domain containing 2	3356	0.38
chr1_226861299_226861450	0.28	ITPKB-IT1	ITPKB intronic transcript 1 (non-protein coding)	1394	0.44
chr2_113941506_113941761	0.28	AC016683.5		8696	0.14
chr1_231747664_231747892	0.28	LINC00582	long intergenic non-protein coding RNA 582	58	0.98
chr10_75718412_75718592	0.28	C10orf55	chromosome 10 open reading frame 55	35967	0.11
chr1_145759757_145760123	0.28	PDZK1	PDZ domain containing 1	16677	0.17
chrX_118809483_118809939	0.28	SEPT6	septin 6	17081	0.16
chr2_225797953_225798104	0.27	DOCK10	dedicator of cytokinesis 10	13754	0.29
chr12_47801866_47802024	0.27	ENSG00000264906	.	43893	0.16
chr10_112641848_112641999	0.27	PDCD4-AS1	PDCD4 antisense RNA 1	9932	0.13
chr6_130454910_130455146	0.27	RP11-73O6.3		4313	0.28
chr3_161112424_161112630	0.27	SPTSSB	serine palmitoyltransferase, small subunit B	21859	0.27
chr12_132089385_132089651	0.27	ENSG00000212154	.	56090	0.15
chr3_52282472_52282623	0.27	PPM1M	protein phosphatase, Mg2+/Mn2+ dependent, 1M	430	0.67
chr12_94677063_94677247	0.27	RP11-1105G2.3	Uncharacterized protein	3199	0.21
chr2_37680152_37680303	0.26	ENSG00000253078	.	17476	0.23
chr15_64152644_64152888	0.26	ENSG00000199156	.	10452	0.21
chr16_23908795_23909009	0.26	PRKCB	protein kinase C, beta	60358	0.13
chr2_42470186_42470352	0.26	EML4	echinoderm microtubule associated protein like 4	58124	0.13
chr1_231749795_231749989	0.26	LINC00582	long intergenic non-protein coding RNA 582	2056	0.33
chr11_4028359_4028548	0.26	STIM1	stromal interaction molecule 1	51526	0.12
chr1_6519581_6519934	0.26	TNFRSF25	tumor necrosis factor receptor superfamily, member 25	5933	0.11
chr7_43663826_43664098	0.26	COA1	cytochrome c oxidase assembly factor 1 homolog (S. cerevisiae)	25933	0.17
chrX_123478313_123478464	0.26	SH2D1A	SH2 domain containing 1A	1806	0.51
chr8_116661022_116661259	0.26	TRPS1	trichorhinophalangeal syndrome I	12765	0.31
chr8_134094410_134094637	0.26	SLA	Src-like-adaptor	20198	0.21
chr17_40552596_40552747	0.25	ENSG00000221020	.	1644	0.25
chr1_23852013_23852546	0.25	E2F2	E2F transcription factor 2	5433	0.19
chr17_47898453_47898676	0.25	RP11-304F15.3		24708	0.12
chr14_64338735_64338886	0.25	SYNE2	spectrin repeat containing, nuclear envelope 2	19078	0.2
chrX_153945626_153945979	0.25	GAB3	GRB2-associated binding protein 3	33530	0.1
chr6_109793071_109793295	0.25	MICAL1	microtubule associated monooxygenase, calponin and LIM domain containing 1	6012	0.12
chrX_135736140_135736427	0.25	CD40LG	CD40 ligand	5897	0.19
chr3_63966604_63966755	0.25	ATXN7	ataxin 7	13259	0.13
chr17_78822051_78822202	0.25	RP11-28G8.1		42694	0.13
chr11_95873954_95874105	0.25	ENSG00000266192	.	200573	0.02
chr6_37476350_37476501	0.25	CCDC167	coiled-coil domain containing 167	8727	0.21
chr13_27868032_27868251	0.25	RASL11A	RAS-like, family 11, member A	23677	0.11
chr2_182170742_182171002	0.25	ENSG00000266705	.	493	0.89
chr11_68233185_68233560	0.25	PPP6R3	protein phosphatase 6, regulatory subunit 3	5091	0.2
chr8_120844517_120844841	0.25	TAF2	TAF2 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 150kDa	424	0.82
chr2_235209319_235209470	0.25	ARL4C	ADP-ribosylation factor-like 4C	195850	0.03
chr7_17339233_17339426	0.25	AC003075.4		348	0.82
chrX_7009158_7009309	0.25	ENSG00000264268	.	56668	0.14
chr20_56009872_56010023	0.25	RP4-800J21.3		41829	0.12
chr2_241978710_241978861	0.25	SNED1	sushi, nidogen and EGF-like domains 1	748	0.57
chr10_52395779_52396046	0.25	SGMS1	sphingomyelin synthase 1	11117	0.18
chr12_57402257_57402505	0.25	ZBTB39	zinc finger and BTB domain containing 39	2151	0.17
chr14_69619079_69619292	0.25	DCAF5	DDB1 and CUL4 associated factor 5	131	0.96
chr5_172455012_172455163	0.25	ENSG00000212402	.	7356	0.16
chr1_87171609_87171760	0.24	SH3GLB1	SH3-domain GRB2-like endophilin B1	1106	0.4
chr19_16372760_16372931	0.24	CTD-2562J15.6		31541	0.12
chr7_37355725_37356299	0.24	ELMO1	engulfment and cell motility 1	26355	0.19
chr14_22984704_22984925	0.24	TRAJ15	T cell receptor alpha joining 15	13766	0.1
chr14_91874860_91875123	0.24	CCDC88C	coiled-coil domain containing 88C	8699	0.24
chr2_27465198_27465349	0.24	CAD	carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase	484	0.65
chr2_89052042_89052193	0.24	ENSG00000221686	.	14718	0.13
chr1_207095862_207096179	0.24	FAIM3	Fas apoptotic inhibitory molecule 3	521	0.73
chr10_28865947_28866098	0.24	WAC	WW domain containing adaptor with coiled-coil	42970	0.13
chr20_61958160_61958405	0.24	COL20A1	collagen, type XX, alpha 1	6831	0.12
chr16_68101897_68102289	0.24	ENSG00000221789	.	12306	0.09
chr12_21829380_21829559	0.24	RP11-59N23.3		14222	0.18
chr7_50306943_50307629	0.23	IKZF1	IKAROS family zinc finger 1 (Ikaros)	37038	0.2
chr8_134065609_134065962	0.23	SLA	Src-like-adaptor	6818	0.26
chr20_42347749_42347916	0.23	GTSF1L	gametocyte specific factor 1-like	7505	0.23
chr11_128589269_128589420	0.23	SENCR	smooth muscle and endothelial cell enriched migration/differentiation-associated long non-coding RNA	23426	0.17
chr7_143399470_143399621	0.23	FAM115C	family with sequence similarity 115, member C	12323	0.19
chr2_135039842_135039993	0.23	MGAT5	mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase	28087	0.22
chr11_13326530_13326681	0.23	ARNTL	aryl hydrocarbon receptor nuclear translocator-like	4928	0.29
chr18_54540471_54540622	0.23	RP11-383D22.1		655	0.75
chr2_198859578_198859729	0.23	PLCL1	phospholipase C-like 1	88883	0.1
chr1_32311994_32312145	0.23	SPOCD1	SPOC domain containing 1	30417	0.13
chr15_38979216_38979456	0.23	C15orf53	chromosome 15 open reading frame 53	9463	0.29
chr2_149297947_149298273	0.23	MBD5	methyl-CpG binding domain protein 5	71816	0.12
chr9_33416779_33416989	0.23	RP11-311H10.4		14029	0.14
chr16_89805141_89805292	0.23	FANCA	Fanconi anemia, complementation group A	1270	0.3
chr10_94875409_94875560	0.23	CYP26A1	cytochrome P450, family 26, subfamily A, polypeptide 1	41837	0.15
chr7_7687864_7688015	0.23	RPA3	replication protein A3, 14kDa	7336	0.27
chr1_90117224_90117495	0.23	LRRC8C	leucine rich repeat containing 8 family, member C	18728	0.16
chr15_31460675_31460826	0.23	TRPM1	transient receptor potential cation channel, subfamily M, member 1	7274	0.28
chr20_51757901_51758052	0.23	RP11-15M15.1		38113	0.14
chr4_109051355_109051506	0.22	LEF1	lymphoid enhancer-binding factor 1	36027	0.17
chr3_18444556_18444707	0.22	RP11-158G18.1		6496	0.24
chr11_67414492_67414700	0.22	ACY3	aspartoacylase (aminocyclase) 3	458	0.69
chr1_65377943_65378171	0.22	JAK1	Janus kinase 1	54130	0.15
chr9_98512665_98512816	0.22	DKFZP434H0512	Protein LOC100506667; Putative uncharacterized protein DKFZp434H0512	21865	0.24
chr3_45739129_45739318	0.22	SACM1L	SAC1 suppressor of actin mutations 1-like (yeast)	8272	0.18
chr22_20846545_20846877	0.22	KLHL22	kelch-like family member 22	867	0.4
chr10_6515310_6515461	0.22	PRKCQ	protein kinase C, theta	106816	0.07
chr9_37301598_37301921	0.22	ENSG00000216070	.	5658	0.23
chr6_161647774_161647954	0.22	AGPAT4	1-acylglycerol-3-phosphate O-acyltransferase 4	47187	0.2
chr13_41011930_41012431	0.22	ENSG00000252812	.	30603	0.23
chr1_93435226_93435377	0.22	ENSG00000252121	.	34	0.96
chr8_66865558_66865709	0.22	DNAJC5B	DnaJ (Hsp40) homolog, subfamily C, member 5 beta	68162	0.12
chr8_144287903_144288067	0.22	GPIHBP1	glycosylphosphatidylinositol anchored high density lipoprotein binding protein 1	7083	0.15
chr2_85066151_85066429	0.22	TRABD2A	TraB domain containing 2A	41916	0.14
chr1_89996259_89996410	0.22	LRRC8B	leucine rich repeat containing 8 family, member B	5872	0.26
chr4_40231477_40231628	0.22	RHOH	ras homolog family member H	29588	0.18
chr14_71421573_71421779	0.22	PCNX	pecanex homolog (Drosophila)	47220	0.19
chrX_135738817_135739027	0.22	CD40LG	CD40 ligand	8536	0.18
chr1_183467594_183467745	0.22	ENSG00000265042	.	12230	0.2
chr3_68139067_68139395	0.22	FAM19A1	family with sequence similarity 19 (chemokine (C-C motif)-like), member A1	83858	0.11
chr12_122327188_122327339	0.22	PSMD9	proteasome (prosome, macropain) 26S subunit, non-ATPase, 9	571	0.69
chr11_73715681_73716026	0.22	UCP3	uncoupling protein 3 (mitochondrial, proton carrier)	2496	0.23
chr19_8676942_8677296	0.21	ADAMTS10	ADAM metallopeptidase with thrombospondin type 1 motif, 10	1534	0.33
chr13_114917525_114917690	0.21	RASA3	RAS p21 protein activator 3	19521	0.2
chr18_56382154_56382522	0.21	RP11-126O1.4		37492	0.12
chr1_144364764_144364915	0.21	PPIAL4B	peptidylprolyl isomerase A (cyclophilin A)-like 4B	593	0.76
chr22_17083501_17083652	0.21	ENSG00000221084	.	3882	0.2
chr2_228329125_228329444	0.21	ENSG00000266382	.	7564	0.21
chr3_60028818_60028969	0.21	NPCDR1	nasopharyngeal carcinoma, down-regulated 1	71310	0.14
chr15_38851839_38852473	0.21	RASGRP1	RAS guanyl releasing protein 1 (calcium and DAG-regulated)	127	0.96
chr12_29533290_29533527	0.21	ERGIC2	ERGIC and golgi 2	675	0.7
chr3_58102239_58102390	0.21	FLNB	filamin B, beta	33279	0.17
chr21_38758220_38758371	0.21	DYRK1A	dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A	18412	0.19
chr3_18766132_18766453	0.21	ENSG00000228956	.	20944	0.29
chr1_40307131_40307282	0.21	ENSG00000202222	.	40144	0.09
chr5_14983835_14984240	0.21	ENSG00000212036	.	73288	0.11
chr7_42276182_42276486	0.21	GLI3	GLI family zinc finger 3	278	0.96
chr16_84641040_84641383	0.21	COTL1	coactosin-like 1 (Dictyostelium)	10454	0.17
chr16_24745519_24745772	0.21	TNRC6A	trinucleotide repeat containing 6A	4611	0.31
chr2_106468021_106468172	0.21	NCK2	NCK adaptor protein 2	108	0.97
chr15_64108507_64108658	0.21	HERC1	HECT and RLD domain containing E3 ubiquitin protein ligase family member 1	17502	0.22
chr5_50010543_50010746	0.21	PARP8	poly (ADP-ribose) polymerase family, member 8	47253	0.2
chr3_177661794_177662251	0.21	ENSG00000199858	.	63545	0.15
chr3_118937770_118937921	0.21	B4GALT4-AS1	B4GALT4 antisense RNA 1	7488	0.16
chr17_37618802_37619244	0.21	CDK12	cyclin-dependent kinase 12	731	0.59
chr7_50357344_50357742	0.21	IKZF1	IKAROS family zinc finger 1 (Ikaros)	9225	0.29
chr11_128336164_128336315	0.21	ETS1	v-ets avian erythroblastosis virus E26 oncogene homolog 1	39050	0.19
chr1_149552322_149552473	0.21	PPIAL4C	peptidylprolyl isomerase A (cyclophilin A)-like 4C	606	0.67
chr2_237455567_237455899	0.21	ACKR3	atypical chemokine receptor 3	20697	0.23
chr1_147955924_147956075	0.21	PPIAL4A	peptidylprolyl isomerase A (cyclophilin A)-like 4A	580	0.76
chr19_39369781_39369998	0.21	RINL	Ras and Rab interactor-like	970	0.3
chr3_112055898_112056180	0.20	CD200	CD200 molecule	4014	0.29
chr12_47618220_47618574	0.20	PCED1B	PC-esterase domain containing 1B	1069	0.57
chr7_32923310_32923501	0.20	KBTBD2	kelch repeat and BTB (POZ) domain containing 2	7360	0.23
chr3_128894982_128895182	0.20	CNBP	CCHC-type zinc finger, nucleic acid binding protein	7660	0.13
chr5_176867837_176867988	0.20	PRR7-AS1	PRR7 antisense RNA 1	3566	0.12
chr7_150167142_150167293	0.20	GIMAP8	GTPase, IMAP family member 8	19499	0.16
chr5_35836543_35836754	0.20	CTD-2113L7.1		9528	0.2
chr17_36124947_36125098	0.20	HNF1B	HNF1 homeobox B	19785	0.17
chr19_48081106_48081277	0.20	ENSG00000264280	.	3089	0.19
chr7_150199572_150199895	0.20	GIMAP7	GTPase, IMAP family member 7	12185	0.18
chr4_48344741_48344971	0.20	SLAIN2	SLAIN motif family, member 2	1517	0.49
chr2_148056915_148057066	0.20	ENSG00000238860	.	24549	0.25
chr7_116505510_116505661	0.20	CAPZA2	capping protein (actin filament) muscle Z-line, alpha 2	2931	0.26
chr5_39207369_39207672	0.20	FYB	FYN binding protein	4391	0.32
chr1_27682575_27682843	0.20	MAP3K6	mitogen-activated protein kinase kinase kinase 6	253	0.87
chr13_74288455_74288993	0.20	KLF12	Kruppel-like factor 12	280462	0.01
chr3_46016644_46016795	0.20	FYCO1	FYVE and coiled-coil domain containing 1	9768	0.18
chr14_99397206_99397489	0.20	C14orf177	chromosome 14 open reading frame 177	219390	0.02
chr9_135363318_135363556	0.20	ENSG00000252521	.	66409	0.1
chr10_6537179_6537330	0.20	PRKCQ	protein kinase C, theta	84947	0.1
chr10_28823050_28823201	0.20	WAC	WW domain containing adaptor with coiled-coil	73	0.96
chr12_14568563_14568714	0.20	ATF7IP	activating transcription factor 7 interacting protein	1209	0.56
chr7_55536365_55536572	0.20	VOPP1	vesicular, overexpressed in cancer, prosurvival protein 1	47302	0.16
chr3_14274255_14274511	0.20	XPC	xeroderma pigmentosum, complementation group C	54100	0.12
chr1_91488978_91489129	0.20	ZNF644	zinc finger protein 644	1224	0.65
chr14_99691163_99691558	0.20	AL109767.1		37925	0.16
chr8_29964950_29965250	0.20	LEPROTL1	leptin receptor overlapping transcript-like 1	5644	0.16
chr9_80688940_80689103	0.20	GNAQ	guanine nucleotide binding protein (G protein), q polypeptide	42647	0.19
chr1_168504447_168504842	0.20	XCL2	chemokine (C motif) ligand 2	8591	0.25
chr11_60880867_60881107	0.20	CD5	CD5 molecule	11006	0.17
chr3_71098763_71098914	0.20	FOXP1	forkhead box P1	15239	0.3
chr6_129602102_129602531	0.20	ENSG00000252554	.	155809	0.04
chr10_76347304_76347495	0.20	ENSG00000206756	.	36249	0.2
chr13_41186364_41186802	0.20	FOXO1	forkhead box O1	54151	0.14
chr20_43524593_43524744	0.20	YWHAB	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta	10275	0.14
chr3_11884369_11884520	0.20	TAMM41	TAM41, mitochondrial translocator assembly and maintenance protein, homolog (S. cerevisiae)	3802	0.34
chr3_56500296_56500447	0.20	ERC2	ELKS/RAB6-interacting/CAST family member 2	2020	0.46
chrX_39178748_39178899	0.20	ENSG00000207122	.	238285	0.02
chr16_27244955_27245106	0.20	NSMCE1	non-SMC element 1 homolog (S. cerevisiae)	631	0.7
chr2_70269712_70269962	0.20	PCBP1-AS1	PCBP1 antisense RNA 1	11080	0.17
chr15_22474307_22474699	0.20	IGHV4OR15-8	immunoglobulin heavy variable 4/OR15-8 (non-functional)	1150	0.36
chr20_1632246_1632518	0.20	SIRPG	signal-regulatory protein gamma	359	0.83
chr10_126351420_126351571	0.20	FAM53B-AS1	FAM53B antisense RNA 1	40699	0.16

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of PKNOX1_TGIF2

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	0.5	GO:0030223	neutrophil differentiation(GO:0030223)
0.1	0.5	GO:0033152	immunoglobulin V(D)J recombination(GO:0033152)
0.1	0.1	GO:0002326	B cell lineage commitment(GO:0002326)
0.1	0.5	GO:0009313	oligosaccharide catabolic process(GO:0009313)
0.1	0.4	GO:0001911	negative regulation of leukocyte mediated cytotoxicity(GO:0001911)
0.1	0.1	GO:0010831	positive regulation of myotube differentiation(GO:0010831)
0.1	0.2	GO:0060743	epithelial cell maturation involved in prostate gland development(GO:0060743)
0.1	0.3	GO:0045589	regulation of regulatory T cell differentiation(GO:0045589)
0.1	0.6	GO:0002839	regulation of response to tumor cell(GO:0002834) positive regulation of response to tumor cell(GO:0002836) regulation of immune response to tumor cell(GO:0002837) positive regulation of immune response to tumor cell(GO:0002839)
0.1	0.2	GO:0021798	forebrain dorsal/ventral pattern formation(GO:0021798)
0.1	0.3	GO:1901339	activation of store-operated calcium channel activity(GO:0032237) regulation of store-operated calcium channel activity(GO:1901339) positive regulation of store-operated calcium channel activity(GO:1901341)
0.1	0.3	GO:0002517	T cell tolerance induction(GO:0002517) regulation of T cell tolerance induction(GO:0002664) positive regulation of T cell tolerance induction(GO:0002666)
0.1	0.3	GO:0070670	response to interleukin-4(GO:0070670)
0.1	0.3	GO:0048096	chromatin-mediated maintenance of transcription(GO:0048096)
0.1	0.2	GO:0035405	histone-threonine phosphorylation(GO:0035405)
0.1	0.2	GO:0001821	histamine secretion(GO:0001821)
0.1	0.4	GO:0007172	signal complex assembly(GO:0007172)
0.1	0.2	GO:0006104	succinyl-CoA metabolic process(GO:0006104)
0.0	0.1	GO:0045066	regulatory T cell differentiation(GO:0045066)
0.0	0.1	GO:0002313	mature B cell differentiation involved in immune response(GO:0002313)
0.0	0.1	GO:0045074	interleukin-10 biosynthetic process(GO:0042091) regulation of interleukin-10 biosynthetic process(GO:0045074)
0.0	0.1	GO:0045056	transcytosis(GO:0045056)
0.0	0.1	GO:0061154	endothelial tube morphogenesis(GO:0061154)
0.0	0.1	GO:0050862	positive regulation of T cell receptor signaling pathway(GO:0050862)
0.0	0.2	GO:0045898	regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045898)
0.0	0.1	GO:0007571	age-dependent response to oxidative stress(GO:0001306) age-dependent general metabolic decline(GO:0007571)
0.0	0.1	GO:0070682	proteasome regulatory particle assembly(GO:0070682)
0.0	0.1	GO:0010040	response to iron(II) ion(GO:0010040)
0.0	0.2	GO:0046831	regulation of RNA export from nucleus(GO:0046831)
0.0	0.3	GO:0006491	N-glycan processing(GO:0006491)
0.0	0.1	GO:0031580	membrane raft polarization(GO:0001766) membrane raft distribution(GO:0031580)
0.0	0.2	GO:0090286	cytoskeletal anchoring at nuclear membrane(GO:0090286)
0.0	0.1	GO:0009048	dosage compensation by inactivation of X chromosome(GO:0009048)
0.0	0.1	GO:0050686	negative regulation of mRNA processing(GO:0050686) negative regulation of mRNA metabolic process(GO:1903312)
0.0	0.0	GO:0072217	negative regulation of metanephros development(GO:0072217)
0.0	0.1	GO:0052251	induction by organism of defense response of other organism involved in symbiotic interaction(GO:0052251)
0.0	0.1	GO:0051832	evasion or tolerance of host defenses by virus(GO:0019049) avoidance of host defenses(GO:0044413) evasion or tolerance of host defenses(GO:0044415) avoidance of defenses of other organism involved in symbiotic interaction(GO:0051832) evasion or tolerance of defenses of other organism involved in symbiotic interaction(GO:0051834)
0.0	0.1	GO:0035455	response to interferon-alpha(GO:0035455)
0.0	0.2	GO:0022614	membrane to membrane docking(GO:0022614)
0.0	0.1	GO:0002323	natural killer cell activation involved in immune response(GO:0002323) natural killer cell degranulation(GO:0043320)
0.0	0.2	GO:0007256	activation of JNKK activity(GO:0007256)
0.0	0.1	GO:0032814	regulation of natural killer cell activation(GO:0032814)
0.0	0.1	GO:0060677	ureteric bud elongation(GO:0060677)
0.0	0.2	GO:0002726	positive regulation of T cell cytokine production(GO:0002726)
0.0	0.1	GO:0002890	negative regulation of B cell mediated immunity(GO:0002713) negative regulation of immunoglobulin mediated immune response(GO:0002890)
0.0	0.1	GO:1901419	regulation of response to alcohol(GO:1901419)
0.0	0.1	GO:0070340	detection of bacterial lipoprotein(GO:0042494) detection of bacterial lipopeptide(GO:0070340)
0.0	0.1	GO:1901978	positive regulation of spindle checkpoint(GO:0090232) regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090266) positive regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090267) positive regulation of cell cycle checkpoint(GO:1901978) regulation of mitotic spindle checkpoint(GO:1903504)
0.0	0.2	GO:0008653	lipopolysaccharide metabolic process(GO:0008653)
0.0	0.1	GO:0046642	negative regulation of alpha-beta T cell proliferation(GO:0046642)
0.0	0.1	GO:0090206	negative regulation of cholesterol biosynthetic process(GO:0045541) negative regulation of cholesterol metabolic process(GO:0090206)
0.0	0.1	GO:0002507	tolerance induction(GO:0002507)
0.0	0.1	GO:0002820	negative regulation of adaptive immune response(GO:0002820) negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains(GO:0002823)
0.0	0.3	GO:0043368	positive T cell selection(GO:0043368)
0.0	0.1	GO:0018076	N-terminal peptidyl-lysine acetylation(GO:0018076)
0.0	0.2	GO:0002063	chondrocyte development(GO:0002063)
0.0	0.1	GO:0043374	CD8-positive, alpha-beta T cell activation(GO:0036037) CD8-positive, alpha-beta T cell differentiation(GO:0043374)
0.0	0.2	GO:0051447	negative regulation of meiotic cell cycle(GO:0051447)
0.0	0.1	GO:0006089	lactate metabolic process(GO:0006089)
0.0	0.1	GO:0019856	'de novo' pyrimidine nucleobase biosynthetic process(GO:0006207) pyrimidine nucleobase biosynthetic process(GO:0019856)
0.0	0.2	GO:0090312	regulation of protein deacetylation(GO:0090311) positive regulation of protein deacetylation(GO:0090312)
0.0	0.1	GO:0019276	UDP-N-acetylgalactosamine metabolic process(GO:0019276)
0.0	2.1	GO:0050852	T cell receptor signaling pathway(GO:0050852)
0.0	0.1	GO:0010572	positive regulation of platelet activation(GO:0010572)
0.0	0.1	GO:0070779	D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
0.0	0.1	GO:0046835	carbohydrate phosphorylation(GO:0046835)
0.0	0.1	GO:0052572	response to immune response of other organism involved in symbiotic interaction(GO:0052564) response to host immune response(GO:0052572)
0.0	0.1	GO:0015917	aminophospholipid transport(GO:0015917)
0.0	0.1	GO:0006003	fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.0	0.3	GO:0033523	histone H2B ubiquitination(GO:0033523)
0.0	0.1	GO:0009106	lipoate metabolic process(GO:0009106)
0.0	0.2	GO:0032735	positive regulation of interleukin-12 production(GO:0032735)
0.0	0.1	GO:0097709	connective tissue replacement involved in inflammatory response wound healing(GO:0002248) connective tissue replacement(GO:0097709)
0.0	0.1	GO:0042989	sequestering of actin monomers(GO:0042989)
0.0	0.1	GO:0032653	regulation of interleukin-10 production(GO:0032653)
0.0	0.1	GO:0032486	Rap protein signal transduction(GO:0032486)
0.0	0.2	GO:0000381	regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.0	0.1	GO:0000281	mitotic cytokinesis(GO:0000281)
0.0	0.1	GO:0070932	histone H3 deacetylation(GO:0070932) histone H4 deacetylation(GO:0070933)
0.0	0.1	GO:0030854	positive regulation of granulocyte differentiation(GO:0030854)
0.0	0.1	GO:0006772	thiamine metabolic process(GO:0006772)
0.0	0.3	GO:0000303	response to superoxide(GO:0000303)
0.0	0.1	GO:0000042	protein targeting to Golgi(GO:0000042) establishment of protein localization to Golgi(GO:0072600)
0.0	0.1	GO:0034755	iron ion transmembrane transport(GO:0034755)
0.0	0.1	GO:0048087	positive regulation of developmental pigmentation(GO:0048087)
0.0	0.3	GO:0008105	asymmetric protein localization(GO:0008105)
0.0	0.0	GO:0002693	positive regulation of cellular extravasation(GO:0002693)
0.0	0.1	GO:0009301	snRNA transcription(GO:0009301)
0.0	0.0	GO:0060397	JAK-STAT cascade involved in growth hormone signaling pathway(GO:0060397)
0.0	0.1	GO:0045793	positive regulation of cell size(GO:0045793)
0.0	0.1	GO:0031061	negative regulation of histone methylation(GO:0031061)
0.0	0.1	GO:0042518	negative regulation of tyrosine phosphorylation of Stat3 protein(GO:0042518)
0.0	0.0	GO:0002495	antigen processing and presentation of peptide antigen via MHC class II(GO:0002495)
0.0	0.1	GO:0030505	inorganic diphosphate transport(GO:0030505)
0.0	0.0	GO:1902622	regulation of neutrophil chemotaxis(GO:0090022) regulation of neutrophil migration(GO:1902622)
0.0	0.2	GO:0044409	entry into host cell(GO:0030260) entry into host(GO:0044409) entry into cell of other organism involved in symbiotic interaction(GO:0051806) entry into other organism involved in symbiotic interaction(GO:0051828)
0.0	0.1	GO:0006538	glutamate catabolic process(GO:0006538)
0.0	0.1	GO:0033522	histone H2A ubiquitination(GO:0033522)
0.0	0.1	GO:0033629	negative regulation of cell adhesion mediated by integrin(GO:0033629)
0.0	0.2	GO:0002717	positive regulation of natural killer cell mediated immunity(GO:0002717) positive regulation of natural killer cell mediated cytotoxicity(GO:0045954)
0.0	0.1	GO:0071830	chylomicron remnant clearance(GO:0034382) triglyceride-rich lipoprotein particle clearance(GO:0071830)
0.0	0.0	GO:0072577	endothelial cell apoptotic process(GO:0072577) epithelial cell apoptotic process(GO:1904019) regulation of epithelial cell apoptotic process(GO:1904035) regulation of endothelial cell apoptotic process(GO:2000351)
0.0	0.1	GO:0009186	deoxyribonucleoside diphosphate metabolic process(GO:0009186)
0.0	0.1	GO:0033261	obsolete regulation of S phase(GO:0033261)
0.0	0.2	GO:0006607	NLS-bearing protein import into nucleus(GO:0006607)
0.0	0.1	GO:0019987	obsolete negative regulation of anti-apoptosis(GO:0019987)
0.0	0.0	GO:0032497	detection of lipopolysaccharide(GO:0032497)
0.0	0.1	GO:0002862	negative regulation of inflammatory response to antigenic stimulus(GO:0002862)
0.0	0.1	GO:0090050	positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050) positive regulation of sprouting angiogenesis(GO:1903672)
0.0	0.3	GO:0016601	Rac protein signal transduction(GO:0016601)
0.0	0.0	GO:0002282	microglial cell activation involved in immune response(GO:0002282)
0.0	0.1	GO:0045722	positive regulation of gluconeogenesis(GO:0045722)
0.0	0.5	GO:0070936	protein K48-linked ubiquitination(GO:0070936)
0.0	0.1	GO:0017182	peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183)
0.0	0.0	GO:0032075	positive regulation of nuclease activity(GO:0032075)
0.0	0.1	GO:0006686	sphingomyelin biosynthetic process(GO:0006686)
0.0	0.1	GO:0010508	positive regulation of autophagy(GO:0010508)
0.0	0.1	GO:0006269	DNA replication, synthesis of RNA primer(GO:0006269)
0.0	0.1	GO:0060340	positive regulation of type I interferon-mediated signaling pathway(GO:0060340)
0.0	0.1	GO:0045759	negative regulation of action potential(GO:0045759)
0.0	0.1	GO:0090205	positive regulation of cholesterol metabolic process(GO:0090205)
0.0	0.1	GO:0048548	regulation of pinocytosis(GO:0048548)
0.0	0.1	GO:0035025	positive regulation of Rho protein signal transduction(GO:0035025)
0.0	0.1	GO:0035413	positive regulation of catenin import into nucleus(GO:0035413)
0.0	0.1	GO:0032876	regulation of DNA endoreduplication(GO:0032875) negative regulation of DNA endoreduplication(GO:0032876) DNA endoreduplication(GO:0042023)
0.0	0.0	GO:0046877	regulation of saliva secretion(GO:0046877)
0.0	0.1	GO:0050435	beta-amyloid metabolic process(GO:0050435)
0.0	0.1	GO:0003351	epithelial cilium movement(GO:0003351) epithelial cilium movement involved in determination of left/right asymmetry(GO:0060287)
0.0	0.1	GO:0043984	histone H4-K16 acetylation(GO:0043984)
0.0	0.1	GO:0002523	leukocyte migration involved in inflammatory response(GO:0002523)
0.0	0.1	GO:0045943	positive regulation of transcription from RNA polymerase I promoter(GO:0045943)
0.0	0.1	GO:0017121	phospholipid scrambling(GO:0017121)
0.0	0.0	GO:0010535	regulation of activation of JAK2 kinase activity(GO:0010534) positive regulation of activation of JAK2 kinase activity(GO:0010535)
0.0	0.1	GO:0031936	negative regulation of chromatin silencing(GO:0031936)
0.0	0.1	GO:0048388	endosomal lumen acidification(GO:0048388)
0.0	0.1	GO:0014010	Schwann cell proliferation(GO:0014010)
0.0	0.5	GO:1901185	negative regulation of epidermal growth factor receptor signaling pathway(GO:0042059) negative regulation of ERBB signaling pathway(GO:1901185)
0.0	0.1	GO:0032415	regulation of sodium:proton antiporter activity(GO:0032415) regulation of sodium ion transmembrane transport(GO:1902305) regulation of sodium ion transmembrane transporter activity(GO:2000649)
0.0	0.0	GO:0051088	PMA-inducible membrane protein ectodomain proteolysis(GO:0051088)
0.0	0.1	GO:0046827	positive regulation of protein export from nucleus(GO:0046827)
0.0	0.1	GO:0046621	negative regulation of organ growth(GO:0046621)
0.0	0.1	GO:0007063	regulation of sister chromatid cohesion(GO:0007063)
0.0	0.1	GO:0051657	maintenance of organelle location(GO:0051657)
0.0	0.1	GO:0032667	interleukin-23 production(GO:0032627) regulation of interleukin-23 production(GO:0032667)
0.0	0.1	GO:0045003	DNA recombinase assembly(GO:0000730) double-strand break repair via synthesis-dependent strand annealing(GO:0045003)
0.0	0.1	GO:0045136	development of secondary sexual characteristics(GO:0045136)
0.0	0.1	GO:0033169	histone H3-K9 demethylation(GO:0033169)
0.0	0.0	GO:0001661	conditioned taste aversion(GO:0001661)
0.0	0.1	GO:0001787	natural killer cell proliferation(GO:0001787)
0.0	0.1	GO:0034260	negative regulation of GTPase activity(GO:0034260)
0.0	0.1	GO:0006422	aspartyl-tRNA aminoacylation(GO:0006422)
0.0	0.0	GO:0060235	lens induction in camera-type eye(GO:0060235)
0.0	0.0	GO:0035844	cloaca development(GO:0035844) cloacal septation(GO:0060197)
0.0	0.1	GO:0061384	heart trabecula formation(GO:0060347) heart trabecula morphogenesis(GO:0061384)
0.0	0.2	GO:0032456	endocytic recycling(GO:0032456)
0.0	0.0	GO:0060049	regulation of protein glycosylation(GO:0060049)
0.0	0.1	GO:0048312	intracellular distribution of mitochondria(GO:0048312)
0.0	0.0	GO:0048293	isotype switching to IgE isotypes(GO:0048289) regulation of isotype switching to IgE isotypes(GO:0048293)
0.0	0.1	GO:0042761	very long-chain fatty acid biosynthetic process(GO:0042761)
0.0	0.1	GO:0030033	microvillus assembly(GO:0030033) microvillus organization(GO:0032528)
0.0	0.1	GO:0006978	DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:0006978)
0.0	0.1	GO:0007064	mitotic sister chromatid cohesion(GO:0007064)
0.0	0.0	GO:0045767	obsolete regulation of anti-apoptosis(GO:0045767)
0.0	0.1	GO:0008608	attachment of spindle microtubules to kinetochore(GO:0008608)
0.0	0.0	GO:0033632	regulation of cell-cell adhesion mediated by integrin(GO:0033632)
0.0	0.0	GO:0031282	regulation of guanylate cyclase activity(GO:0031282)
0.0	0.0	GO:0001845	phagolysosome assembly(GO:0001845) phagosome maturation(GO:0090382)
0.0	0.0	GO:0030952	establishment or maintenance of cytoskeleton polarity(GO:0030952)
0.0	0.0	GO:0006922	obsolete cleavage of lamin involved in execution phase of apoptosis(GO:0006922)
0.0	0.0	GO:0010447	response to acidic pH(GO:0010447)
0.0	0.2	GO:1904031	positive regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045737) positive regulation of cyclin-dependent protein kinase activity(GO:1904031)
0.0	0.0	GO:0046015	carbon catabolite regulation of transcription(GO:0045990) regulation of transcription by glucose(GO:0046015)
0.0	0.0	GO:0033033	negative regulation of myeloid cell apoptotic process(GO:0033033)
0.0	0.0	GO:0015801	aromatic amino acid transport(GO:0015801)
0.0	0.1	GO:0006857	oligopeptide transport(GO:0006857)
0.0	0.1	GO:0010759	positive regulation of macrophage chemotaxis(GO:0010759)
0.0	0.1	GO:0001782	B cell homeostasis(GO:0001782)
0.0	0.0	GO:0006610	ribosomal protein import into nucleus(GO:0006610)
0.0	0.1	GO:0046579	positive regulation of Ras protein signal transduction(GO:0046579)
0.0	0.2	GO:0007032	endosome organization(GO:0007032)
0.0	0.1	GO:0003056	regulation of vascular smooth muscle contraction(GO:0003056)
0.0	0.0	GO:0048261	negative regulation of receptor-mediated endocytosis(GO:0048261)
0.0	0.0	GO:0010837	regulation of keratinocyte proliferation(GO:0010837)
0.0	0.1	GO:0007090	obsolete regulation of S phase of mitotic cell cycle(GO:0007090)
0.0	0.1	GO:0035092	sperm chromatin condensation(GO:0035092)
0.0	0.0	GO:0031440	regulation of mRNA 3'-end processing(GO:0031440) positive regulation of mRNA 3'-end processing(GO:0031442) positive regulation of mRNA processing(GO:0050685) positive regulation of mRNA metabolic process(GO:1903313)
0.0	0.0	GO:0009448	gamma-aminobutyric acid metabolic process(GO:0009448)
0.0	0.0	GO:0006924	activation-induced cell death of T cells(GO:0006924)
0.0	0.1	GO:0032464	positive regulation of protein homooligomerization(GO:0032464)
0.0	0.0	GO:0045163	clustering of voltage-gated potassium channels(GO:0045163)
0.0	0.0	GO:0000019	regulation of mitotic recombination(GO:0000019)
0.0	0.0	GO:0046084	adenine salvage(GO:0006168) purine nucleobase salvage(GO:0043096) adenine metabolic process(GO:0046083) adenine biosynthetic process(GO:0046084)
0.0	0.1	GO:0032715	negative regulation of interleukin-6 production(GO:0032715)
0.0	0.0	GO:0070935	3'-UTR-mediated mRNA stabilization(GO:0070935)
0.0	0.0	GO:0042535	positive regulation of tumor necrosis factor biosynthetic process(GO:0042535)
0.0	0.3	GO:0043124	negative regulation of I-kappaB kinase/NF-kappaB signaling(GO:0043124)
0.0	0.1	GO:0071157	negative regulation of cell cycle arrest(GO:0071157)
0.0	0.0	GO:0006154	adenosine catabolic process(GO:0006154)
0.0	0.0	GO:0048859	formation of anatomical boundary(GO:0048859)
0.0	0.1	GO:0034379	very-low-density lipoprotein particle assembly(GO:0034379)
0.0	0.0	GO:0071698	olfactory placode formation(GO:0030910) olfactory placode development(GO:0071698) olfactory placode morphogenesis(GO:0071699)
0.0	0.0	GO:0006420	arginyl-tRNA aminoacylation(GO:0006420)
0.0	0.1	GO:0006684	sphingomyelin metabolic process(GO:0006684)
0.0	0.2	GO:0060334	regulation of response to interferon-gamma(GO:0060330) regulation of interferon-gamma-mediated signaling pathway(GO:0060334)
0.0	0.0	GO:0030186	melatonin metabolic process(GO:0030186) melatonin biosynthetic process(GO:0030187)
0.0	0.0	GO:0055015	ventricular cardiac muscle cell development(GO:0055015)
0.0	0.0	GO:0042159	lipoprotein catabolic process(GO:0042159)
0.0	0.1	GO:0000089	mitotic metaphase(GO:0000089)
0.0	0.0	GO:0030309	poly-N-acetyllactosamine metabolic process(GO:0030309)
0.0	0.3	GO:0006611	protein export from nucleus(GO:0006611)
0.0	0.1	GO:0000389	mRNA 3'-splice site recognition(GO:0000389)
0.0	0.3	GO:0006997	nucleus organization(GO:0006997)
0.0	0.1	GO:0006983	ER overload response(GO:0006983)
0.0	0.1	GO:0006346	methylation-dependent chromatin silencing(GO:0006346)
0.0	0.1	GO:0045948	positive regulation of translational initiation(GO:0045948)
0.0	0.2	GO:0032008	positive regulation of TOR signaling(GO:0032008)
0.0	0.0	GO:0002478	antigen processing and presentation of exogenous peptide antigen(GO:0002478)
0.0	0.1	GO:0000012	single strand break repair(GO:0000012)
0.0	0.1	GO:0006376	mRNA splice site selection(GO:0006376)
0.0	0.1	GO:0060023	soft palate development(GO:0060023)
0.0	0.0	GO:0061302	smooth muscle cell-matrix adhesion(GO:0061302)
0.0	0.1	GO:0031648	protein destabilization(GO:0031648)
0.0	0.0	GO:1903579	negative regulation of nucleoside metabolic process(GO:0045978) negative regulation of ATP metabolic process(GO:1903579)
0.0	0.0	GO:0040016	embryonic cleavage(GO:0040016)
0.0	0.1	GO:0000266	mitochondrial fission(GO:0000266)
0.0	0.1	GO:0045040	outer mitochondrial membrane organization(GO:0007008) protein import into mitochondrial outer membrane(GO:0045040)
0.0	0.1	GO:0048200	COPI-coated vesicle budding(GO:0035964) Golgi vesicle budding(GO:0048194) Golgi transport vesicle coating(GO:0048200) COPI coating of Golgi vesicle(GO:0048205)
0.0	0.0	GO:0045425	positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process(GO:0045425)
0.0	0.0	GO:0018343	protein farnesylation(GO:0018343)
0.0	0.0	GO:0015705	iodide transport(GO:0015705)
0.0	0.1	GO:0010614	negative regulation of cardiac muscle hypertrophy(GO:0010614)
0.0	0.0	GO:0006007	glucose catabolic process(GO:0006007)
0.0	0.0	GO:0009138	pyrimidine nucleoside diphosphate metabolic process(GO:0009138)
0.0	0.0	GO:0006681	galactosylceramide metabolic process(GO:0006681)
0.0	0.1	GO:0048013	ephrin receptor signaling pathway(GO:0048013)
0.0	0.1	GO:0045116	protein neddylation(GO:0045116)
0.0	0.0	GO:0001833	inner cell mass cell proliferation(GO:0001833)
0.0	0.1	GO:0045071	negative regulation of viral genome replication(GO:0045071)
0.0	0.2	GO:0032012	regulation of ARF protein signal transduction(GO:0032012)
0.0	0.0	GO:0048304	positive regulation of isotype switching to IgG isotypes(GO:0048304)
0.0	0.0	GO:0051451	myoblast migration(GO:0051451)
0.0	0.0	GO:0022417	protein maturation by protein folding(GO:0022417)
0.0	0.1	GO:0015074	DNA integration(GO:0015074)
0.0	0.0	GO:0032055	negative regulation of translation in response to stress(GO:0032055)
0.0	0.0	GO:0032543	mitochondrial translation(GO:0032543)
0.0	0.3	GO:0007257	activation of JUN kinase activity(GO:0007257)
0.0	0.0	GO:0070508	cytokine secretion involved in immune response(GO:0002374) regulation of cytokine secretion involved in immune response(GO:0002739) negative regulation of very-low-density lipoprotein particle remodeling(GO:0010903) sterol import(GO:0035376) cholesterol import(GO:0070508)
0.0	0.1	GO:0006020	inositol metabolic process(GO:0006020)
0.0	0.2	GO:0034199	activation of protein kinase A activity(GO:0034199)
0.0	0.1	GO:0070193	synaptonemal complex organization(GO:0070193)
0.0	0.0	GO:0006384	transcription initiation from RNA polymerase III promoter(GO:0006384)
0.0	0.1	GO:0019673	GDP-mannose metabolic process(GO:0019673)
0.0	0.1	GO:0051775	response to redox state(GO:0051775)
0.0	0.0	GO:0033194	response to hydroperoxide(GO:0033194)
0.0	0.0	GO:0001831	trophectodermal cellular morphogenesis(GO:0001831)
0.0	0.0	GO:0006474	N-terminal protein amino acid acetylation(GO:0006474)
0.0	0.2	GO:0031294	lymphocyte costimulation(GO:0031294) T cell costimulation(GO:0031295)
0.0	0.1	GO:0006069	ethanol metabolic process(GO:0006067) ethanol oxidation(GO:0006069)
0.0	0.0	GO:0060219	camera-type eye photoreceptor cell differentiation(GO:0060219)
0.0	0.1	GO:0006012	galactose metabolic process(GO:0006012)
0.0	0.0	GO:0070059	intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress(GO:0070059)
0.0	0.0	GO:0007191	adenylate cyclase-activating dopamine receptor signaling pathway(GO:0007191)
0.0	0.1	GO:0042771	intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator(GO:0042771)
0.0	0.1	GO:0043508	negative regulation of JUN kinase activity(GO:0043508)
0.0	0.1	GO:0022027	interkinetic nuclear migration(GO:0022027)
0.0	0.1	GO:0050930	induction of positive chemotaxis(GO:0050930)
0.0	0.1	GO:0046348	amino sugar catabolic process(GO:0046348) glucosamine-containing compound catabolic process(GO:1901072)
0.0	0.2	GO:0070206	protein trimerization(GO:0070206)
0.0	0.1	GO:0016255	attachment of GPI anchor to protein(GO:0016255)
0.0	0.1	GO:0060770	negative regulation of epithelial cell proliferation involved in prostate gland development(GO:0060770)
0.0	0.0	GO:0034629	cellular protein complex localization(GO:0034629)
0.0	0.0	GO:0048670	regulation of collateral sprouting(GO:0048670)
0.0	0.0	GO:0016572	histone phosphorylation(GO:0016572)
0.0	0.0	GO:0009263	deoxyribonucleotide biosynthetic process(GO:0009263)
0.0	0.1	GO:0090399	replicative senescence(GO:0090399)
0.0	0.1	GO:0030903	notochord development(GO:0030903)
0.0	0.1	GO:0046834	lipid phosphorylation(GO:0046834)
0.0	0.1	GO:0009086	methionine biosynthetic process(GO:0009086)
0.0	0.5	GO:0006968	cellular defense response(GO:0006968)
0.0	0.1	GO:0006513	protein monoubiquitination(GO:0006513)
0.0	0.1	GO:0015886	heme transport(GO:0015886)
0.0	0.1	GO:0031115	negative regulation of microtubule polymerization(GO:0031115)
0.0	0.0	GO:0035162	embryonic hemopoiesis(GO:0035162)
0.0	0.0	GO:0070296	sarcoplasmic reticulum calcium ion transport(GO:0070296)
0.0	0.0	GO:0043117	positive regulation of vascular permeability(GO:0043117)
0.0	0.2	GO:0030032	lamellipodium assembly(GO:0030032)
0.0	0.0	GO:0031167	rRNA methylation(GO:0031167)
0.0	0.0	GO:0071318	cellular response to ATP(GO:0071318)
0.0	0.0	GO:0051001	negative regulation of nitric-oxide synthase activity(GO:0051001)
0.0	0.0	GO:0070634	transepithelial ammonium transport(GO:0070634)
0.0	0.1	GO:0043968	histone H2A acetylation(GO:0043968)
0.0	0.1	GO:0006891	intra-Golgi vesicle-mediated transport(GO:0006891)
0.0	0.1	GO:0002474	antigen processing and presentation of peptide antigen via MHC class I(GO:0002474)
0.0	0.0	GO:0045022	early endosome to late endosome transport(GO:0045022) vesicle-mediated transport between endosomal compartments(GO:0098927)
0.0	0.1	GO:0098930	axonal transport(GO:0098930)
0.0	0.1	GO:0006477	protein sulfation(GO:0006477)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.5	GO:0045179	apical cortex(GO:0045179)
0.1	0.2	GO:0031235	intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.1	0.2	GO:0042105	alpha-beta T cell receptor complex(GO:0042105)
0.0	0.1	GO:0008540	proteasome regulatory particle, base subcomplex(GO:0008540)
0.0	0.2	GO:0043218	compact myelin(GO:0043218)
0.0	0.2	GO:0034993	microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.0	0.1	GO:0043159	acrosomal matrix(GO:0043159)
0.0	0.3	GO:0001891	phagocytic cup(GO:0001891)
0.0	0.1	GO:0070022	transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.0	0.1	GO:0071942	XPC complex(GO:0071942)
0.0	0.1	GO:0072487	MSL complex(GO:0072487)
0.0	0.3	GO:0019908	nuclear cyclin-dependent protein kinase holoenzyme complex(GO:0019908)
0.0	0.1	GO:0005826	actomyosin contractile ring(GO:0005826)
0.0	0.3	GO:0001772	immunological synapse(GO:0001772)
0.0	0.1	GO:0030914	STAGA complex(GO:0030914)
0.0	0.3	GO:0000307	cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.0	0.1	GO:0034673	inhibin-betaglycan-ActRII complex(GO:0034673)
0.0	0.1	GO:0000164	protein phosphatase type 1 complex(GO:0000164)
0.0	0.1	GO:0043240	Fanconi anaemia nuclear complex(GO:0043240)
0.0	0.1	GO:0034363	intermediate-density lipoprotein particle(GO:0034363)
0.0	0.1	GO:0005797	Golgi medial cisterna(GO:0005797)
0.0	0.1	GO:0031931	TORC1 complex(GO:0031931)
0.0	0.1	GO:0030121	AP-1 adaptor complex(GO:0030121)
0.0	0.1	GO:0005900	oncostatin-M receptor complex(GO:0005900)
0.0	0.3	GO:0031528	microvillus membrane(GO:0031528)
0.0	0.1	GO:0070688	MLL5-L complex(GO:0070688)
0.0	0.3	GO:0016514	SWI/SNF complex(GO:0016514)
0.0	0.1	GO:0044224	juxtaparanode region of axon(GO:0044224)
0.0	0.1	GO:0008537	proteasome activator complex(GO:0008537)
0.0	0.1	GO:0000931	gamma-tubulin large complex(GO:0000931) gamma-tubulin ring complex(GO:0008274)
0.0	0.1	GO:0032045	guanyl-nucleotide exchange factor complex(GO:0032045)
0.0	0.1	GO:0072669	tRNA-splicing ligase complex(GO:0072669)
0.0	0.1	GO:0033256	I-kappaB/NF-kappaB complex(GO:0033256)
0.0	0.1	GO:0031305	integral component of mitochondrial inner membrane(GO:0031305)
0.0	0.2	GO:0010494	cytoplasmic stress granule(GO:0010494)
0.0	0.1	GO:0000791	euchromatin(GO:0000791)
0.0	0.1	GO:0000138	Golgi trans cisterna(GO:0000138)
0.0	0.1	GO:0001931	uropod(GO:0001931) cell trailing edge(GO:0031254)
0.0	0.1	GO:0005662	DNA replication factor A complex(GO:0005662)
0.0	0.2	GO:0033276	transcription factor TFTC complex(GO:0033276)
0.0	0.2	GO:0031080	nuclear pore outer ring(GO:0031080)
0.0	0.1	GO:0070695	FHF complex(GO:0070695)
0.0	0.1	GO:0042827	platelet dense granule(GO:0042827)
0.0	0.1	GO:0034045	pre-autophagosomal structure membrane(GO:0034045)
0.0	0.0	GO:0000137	Golgi cis cisterna(GO:0000137)
0.0	0.1	GO:0000276	mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.0	0.1	GO:0034518	mRNA cap binding complex(GO:0005845) RNA cap binding complex(GO:0034518)
0.0	0.5	GO:0030175	filopodium(GO:0030175)
0.0	0.1	GO:0042101	T cell receptor complex(GO:0042101)
0.0	0.1	GO:0016461	unconventional myosin complex(GO:0016461)
0.0	0.1	GO:0030893	meiotic cohesin complex(GO:0030893)
0.0	0.1	GO:0031371	ubiquitin conjugating enzyme complex(GO:0031371)
0.0	0.1	GO:0008278	cohesin complex(GO:0008278)
0.0	0.1	GO:0035098	ESC/E(Z) complex(GO:0035098)
0.0	0.1	GO:0008250	oligosaccharyltransferase complex(GO:0008250)
0.0	0.0	GO:0042584	chromaffin granule(GO:0042583) chromaffin granule membrane(GO:0042584)
0.0	0.1	GO:0016471	vacuolar proton-transporting V-type ATPase complex(GO:0016471)
0.0	0.3	GO:0046658	anchored component of plasma membrane(GO:0046658)
0.0	0.1	GO:0005952	cAMP-dependent protein kinase complex(GO:0005952)
0.0	0.0	GO:0070188	obsolete Stn1-Ten1 complex(GO:0070188)
0.0	0.2	GO:0005942	phosphatidylinositol 3-kinase complex(GO:0005942)
0.0	0.1	GO:0005664	origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.0	0.1	GO:0001741	XY body(GO:0001741)
0.0	0.3	GO:0000932	cytoplasmic mRNA processing body(GO:0000932)
0.0	0.1	GO:0042382	paraspeckles(GO:0042382)
0.0	0.1	GO:0061202	clathrin-sculpted gamma-aminobutyric acid transport vesicle(GO:0061200) clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane(GO:0061202)
0.0	0.6	GO:0017053	transcriptional repressor complex(GO:0017053)
0.0	0.2	GO:0033116	endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
0.0	0.2	GO:0080008	Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.0	0.1	GO:0045120	pronucleus(GO:0045120)
0.0	0.1	GO:0005641	nuclear envelope lumen(GO:0005641)
0.0	0.1	GO:0045334	clathrin-coated endocytic vesicle(GO:0045334)
0.0	0.2	GO:0005858	axonemal dynein complex(GO:0005858)
0.0	0.1	GO:0005868	cytoplasmic dynein complex(GO:0005868)
0.0	0.1	GO:0031105	septin complex(GO:0031105) septin cytoskeleton(GO:0032156)
0.0	0.1	GO:0005658	alpha DNA polymerase:primase complex(GO:0005658)
0.0	0.0	GO:0010369	chromocenter(GO:0010369)
0.0	0.0	GO:0031312	extrinsic component of organelle membrane(GO:0031312)
0.0	0.0	GO:0033179	proton-transporting V-type ATPase, V0 domain(GO:0033179)
0.0	0.1	GO:0034362	low-density lipoprotein particle(GO:0034362)
0.0	0.1	GO:0071203	WASH complex(GO:0071203)
0.0	0.1	GO:0031463	Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0	0.0	GO:0045323	interleukin-1 receptor complex(GO:0045323)
0.0	0.0	GO:0000407	pre-autophagosomal structure(GO:0000407)
0.0	0.0	GO:0000300	obsolete peripheral to membrane of membrane fraction(GO:0000300)
0.0	0.0	GO:0030312	external encapsulating structure(GO:0030312) external encapsulating structure part(GO:0044462)
0.0	0.1	GO:0031941	filamentous actin(GO:0031941)
0.0	0.1	GO:0035267	NuA4 histone acetyltransferase complex(GO:0035267)
0.0	0.0	GO:0072357	PTW/PP1 phosphatase complex(GO:0072357)
0.0	0.1	GO:0030897	HOPS complex(GO:0030897)
0.0	0.1	GO:0005869	dynactin complex(GO:0005869)
0.0	0.0	GO:0032444	activin responsive factor complex(GO:0032444)
0.0	0.0	GO:0032133	chromosome passenger complex(GO:0032133)
0.0	0.0	GO:0000805	X chromosome(GO:0000805)
0.0	0.1	GO:0045275	mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
0.0	0.1	GO:0030130	clathrin coat of trans-Golgi network vesicle(GO:0030130)
0.0	0.0	GO:0031932	TORC2 complex(GO:0031932) TOR complex(GO:0038201)
0.0	0.1	GO:0005697	telomerase holoenzyme complex(GO:0005697)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.4	GO:0016004	phospholipase activator activity(GO:0016004)
0.1	0.3	GO:0016312	inositol bisphosphate phosphatase activity(GO:0016312)
0.1	0.3	GO:0043175	RNA polymerase core enzyme binding(GO:0043175)
0.1	0.2	GO:0008454	alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.1	0.2	GO:0008420	CTD phosphatase activity(GO:0008420)
0.1	0.2	GO:0035184	histone threonine kinase activity(GO:0035184)
0.1	0.2	GO:0016309	1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
0.1	0.2	GO:0030284	estrogen receptor activity(GO:0030284)
0.1	0.2	GO:0004911	interleukin-2 receptor activity(GO:0004911)
0.1	0.2	GO:0033691	sialic acid binding(GO:0033691)
0.0	0.1	GO:0004775	succinate-CoA ligase (ADP-forming) activity(GO:0004775)
0.0	0.2	GO:0019911	structural constituent of myelin sheath(GO:0019911)
0.0	0.3	GO:0016494	C-X-C chemokine receptor activity(GO:0016494)
0.0	0.5	GO:0016493	C-C chemokine receptor activity(GO:0016493)
0.0	0.1	GO:0034056	estrogen response element binding(GO:0034056)
0.0	0.1	GO:0046935	1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.0	0.2	GO:0004046	aminoacylase activity(GO:0004046)
0.0	0.1	GO:0003987	acetate-CoA ligase activity(GO:0003987)
0.0	0.3	GO:0004691	cAMP-dependent protein kinase activity(GO:0004691)
0.0	0.1	GO:0015925	galactosidase activity(GO:0015925)
0.0	0.2	GO:0004904	interferon receptor activity(GO:0004904)
0.0	0.0	GO:0004774	succinate-CoA ligase activity(GO:0004774)
0.0	0.2	GO:0030676	Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0	0.1	GO:0070273	phosphatidylinositol-4-phosphate binding(GO:0070273)
0.0	0.5	GO:0030159	receptor signaling complex scaffold activity(GO:0030159)
0.0	0.0	GO:0000400	four-way junction DNA binding(GO:0000400)
0.0	0.1	GO:0047756	chondroitin 4-sulfotransferase activity(GO:0047756)
0.0	0.2	GO:0005131	growth hormone receptor binding(GO:0005131)
0.0	1.6	GO:0005070	SH3/SH2 adaptor activity(GO:0005070)
0.0	0.0	GO:0050897	cobalt ion binding(GO:0050897)
0.0	0.1	GO:0032454	histone demethylase activity (H3-K9 specific)(GO:0032454)
0.0	0.1	GO:0003829	beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity(GO:0003829)
0.0	0.1	GO:0004949	cannabinoid receptor activity(GO:0004949)
0.0	0.1	GO:0004974	leukotriene receptor activity(GO:0004974)
0.0	0.4	GO:0005095	GTPase inhibitor activity(GO:0005095)
0.0	0.2	GO:0070008	serine-type exopeptidase activity(GO:0070008)
0.0	0.4	GO:0004697	protein kinase C activity(GO:0004697)
0.0	0.1	GO:0004706	JUN kinase kinase kinase activity(GO:0004706)
0.0	0.3	GO:0043425	bHLH transcription factor binding(GO:0043425)
0.0	0.1	GO:0032137	guanine/thymine mispair binding(GO:0032137)
0.0	0.1	GO:0004748	ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
0.0	0.2	GO:0003688	DNA replication origin binding(GO:0003688)
0.0	0.1	GO:0070326	very-low-density lipoprotein particle receptor binding(GO:0070326)
0.0	0.1	GO:0004957	prostaglandin E receptor activity(GO:0004957)
0.0	0.1	GO:0030375	thyroid hormone receptor coactivator activity(GO:0030375)
0.0	0.2	GO:0034593	phosphatidylinositol bisphosphate phosphatase activity(GO:0034593)
0.0	0.1	GO:0030368	interleukin-17 receptor activity(GO:0030368)
0.0	0.9	GO:0004715	non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.0	0.1	GO:0070492	oligosaccharide binding(GO:0070492)
0.0	0.1	GO:0005068	transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.0	0.1	GO:0043141	ATP-dependent 5'-3' DNA helicase activity(GO:0043141)
0.0	0.2	GO:0016857	racemase and epimerase activity, acting on carbohydrates and derivatives(GO:0016857)
0.0	0.1	GO:0004583	dolichyl-phosphate-glucose-glycolipid alpha-glucosyltransferase activity(GO:0004583)
0.0	0.1	GO:0017056	structural constituent of nuclear pore(GO:0017056)
0.0	0.1	GO:0008607	phosphorylase kinase regulator activity(GO:0008607)
0.0	0.1	GO:0016997	exo-alpha-sialidase activity(GO:0004308) alpha-sialidase activity(GO:0016997)
0.0	0.1	GO:0050733	RS domain binding(GO:0050733)
0.0	0.2	GO:0016884	carbon-nitrogen ligase activity, with glutamine as amido-N-donor(GO:0016884)
0.0	0.1	GO:0008035	high-density lipoprotein particle binding(GO:0008035)
0.0	0.0	GO:0000828	inositol hexakisphosphate kinase activity(GO:0000828) inositol hexakisphosphate 5-kinase activity(GO:0000832)
0.0	0.1	GO:0030911	TPR domain binding(GO:0030911)
0.0	0.2	GO:0051766	inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440) inositol trisphosphate kinase activity(GO:0051766)
0.0	0.1	GO:0004784	superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
0.0	0.1	GO:0070403	NAD+ binding(GO:0070403)
0.0	0.2	GO:0005123	death receptor binding(GO:0005123)
0.0	0.1	GO:0022897	peptide:proton symporter activity(GO:0015333) proton-dependent peptide secondary active transmembrane transporter activity(GO:0022897)
0.0	0.1	GO:0004459	L-lactate dehydrogenase activity(GO:0004459)
0.0	0.1	GO:0003836	beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.0	0.0	GO:0000268	peroxisome targeting sequence binding(GO:0000268)
0.0	0.3	GO:0005487	nucleocytoplasmic transporter activity(GO:0005487)
0.0	0.1	GO:0000404	heteroduplex DNA loop binding(GO:0000404)
0.0	0.1	GO:0004301	epoxide hydrolase activity(GO:0004301)
0.0	0.1	GO:0070053	thrombospondin receptor activity(GO:0070053)
0.0	0.2	GO:0004571	mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.0	0.1	GO:0042156	obsolete zinc-mediated transcriptional activator activity(GO:0042156)
0.0	0.1	GO:0008384	IkappaB kinase activity(GO:0008384)
0.0	0.1	GO:0034450	ubiquitin-ubiquitin ligase activity(GO:0034450) ubiquitin protein ligase activity(GO:0061630) ubiquitin-like protein ligase activity(GO:0061659)
0.0	0.1	GO:0003873	6-phosphofructo-2-kinase activity(GO:0003873)
0.0	0.1	GO:0070087	chromo shadow domain binding(GO:0070087)
0.0	0.1	GO:0051019	mitogen-activated protein kinase binding(GO:0051019)
0.0	0.1	GO:0005094	Rho GDP-dissociation inhibitor activity(GO:0005094)
0.0	0.1	GO:0010340	carboxyl-O-methyltransferase activity(GO:0010340) protein carboxyl O-methyltransferase activity(GO:0051998)
0.0	0.2	GO:0031078	histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041) histone deacetylase activity (H4-K16 specific)(GO:0034739) NAD-dependent histone deacetylase activity (H4-K16 specific)(GO:0046970)
0.0	0.1	GO:0005381	iron ion transmembrane transporter activity(GO:0005381)
0.0	0.1	GO:0008379	thioredoxin peroxidase activity(GO:0008379)
0.0	0.2	GO:0015271	outward rectifier potassium channel activity(GO:0015271)
0.0	0.1	GO:0019237	centromeric DNA binding(GO:0019237)
0.0	0.1	GO:0005315	inorganic phosphate transmembrane transporter activity(GO:0005315)
0.0	0.1	GO:0004525	ribonuclease III activity(GO:0004525) double-stranded RNA-specific ribonuclease activity(GO:0032296)
0.0	0.1	GO:0004591	oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591)
0.0	0.1	GO:0042910	xenobiotic-transporting ATPase activity(GO:0008559) xenobiotic transporter activity(GO:0042910)
0.0	0.2	GO:0005522	profilin binding(GO:0005522)
0.0	0.0	GO:0052659	inositol-1,4,5-trisphosphate 5-phosphatase activity(GO:0052658) inositol-1,3,4,5-tetrakisphosphate 5-phosphatase activity(GO:0052659)
0.0	0.0	GO:0042806	fucose binding(GO:0042806)
0.0	0.0	GO:0046975	histone methyltransferase activity (H3-K36 specific)(GO:0046975)
0.0	0.1	GO:0001727	lipid kinase activity(GO:0001727)
0.0	0.1	GO:0017128	phospholipid scramblase activity(GO:0017128)
0.0	0.3	GO:0004709	MAP kinase kinase kinase activity(GO:0004709)
0.0	0.1	GO:0019788	NEDD8 transferase activity(GO:0019788)
0.0	0.1	GO:0036002	pre-mRNA binding(GO:0036002)
0.0	0.1	GO:0008486	diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486)
0.0	0.3	GO:0043027	cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.0	0.1	GO:0043539	protein serine/threonine kinase activator activity(GO:0043539)
0.0	0.1	GO:0004142	diacylglycerol cholinephosphotransferase activity(GO:0004142)
0.0	0.1	GO:0031013	troponin I binding(GO:0031013)
0.0	0.1	GO:0005114	type II transforming growth factor beta receptor binding(GO:0005114)
0.0	0.1	GO:0071208	histone pre-mRNA DCP binding(GO:0071208)
0.0	0.3	GO:0005164	tumor necrosis factor receptor binding(GO:0005164)
0.0	0.1	GO:0046625	sphingolipid binding(GO:0046625)
0.0	0.1	GO:0051400	BH domain binding(GO:0051400)
0.0	0.2	GO:0008139	nuclear localization sequence binding(GO:0008139)
0.0	0.1	GO:0008526	phosphatidylinositol transporter activity(GO:0008526)
0.0	0.3	GO:0043014	alpha-tubulin binding(GO:0043014)
0.0	0.1	GO:0005314	high-affinity glutamate transmembrane transporter activity(GO:0005314)
0.0	0.1	GO:0031685	adenosine receptor binding(GO:0031685)
0.0	0.1	GO:0008242	omega peptidase activity(GO:0008242)
0.0	0.1	GO:0045294	alpha-catenin binding(GO:0045294)
0.0	0.0	GO:0030235	nitric-oxide synthase regulator activity(GO:0030235)
0.0	0.1	GO:0004351	glutamate decarboxylase activity(GO:0004351)
0.0	0.0	GO:0070653	high-density lipoprotein particle receptor binding(GO:0070653)
0.0	0.0	GO:0004999	vasoactive intestinal polypeptide receptor activity(GO:0004999)
0.0	0.3	GO:0005086	ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0	0.0	GO:0008174	mRNA methyltransferase activity(GO:0008174)
0.0	0.1	GO:0047238	glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity(GO:0047238)
0.0	0.1	GO:0004579	dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.0	0.0	GO:0046404	ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity(GO:0046404) polydeoxyribonucleotide kinase activity(GO:0051733) ATP-dependent polynucleotide kinase activity(GO:0051734)
0.0	0.1	GO:0003964	telomerase activity(GO:0003720) RNA-directed DNA polymerase activity(GO:0003964)
0.0	0.1	GO:0019864	IgG binding(GO:0019864)
0.0	0.4	GO:0003950	NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.0	0.1	GO:0004652	polynucleotide adenylyltransferase activity(GO:0004652)
0.0	0.3	GO:0019198	transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.0	0.1	GO:0004767	sphingomyelin phosphodiesterase activity(GO:0004767)
0.0	0.0	GO:0005176	ErbB-2 class receptor binding(GO:0005176)
0.0	0.2	GO:0035035	histone acetyltransferase binding(GO:0035035)
0.0	0.1	GO:0070410	co-SMAD binding(GO:0070410)
0.0	0.0	GO:0008853	exodeoxyribonuclease III activity(GO:0008853)
0.0	0.0	GO:0004311	farnesyltranstransferase activity(GO:0004311)
0.0	0.0	GO:0005346	purine ribonucleotide transmembrane transporter activity(GO:0005346)
0.0	0.0	GO:0004814	arginine-tRNA ligase activity(GO:0004814)
0.0	0.0	GO:0051864	histone demethylase activity (H3-K36 specific)(GO:0051864)
0.0	0.1	GO:0004127	cytidylate kinase activity(GO:0004127)
0.0	0.1	GO:0070567	cytidylyltransferase activity(GO:0070567)
0.0	0.0	GO:0060230	lipoprotein lipase activator activity(GO:0060230)
0.0	0.0	GO:0070215	obsolete MDM2 binding(GO:0070215)
0.0	0.0	GO:0050698	proteoglycan sulfotransferase activity(GO:0050698)
0.0	0.1	GO:0001784	phosphotyrosine binding(GO:0001784)
0.0	0.1	GO:0016778	diphosphotransferase activity(GO:0016778)
0.0	0.0	GO:0034187	obsolete apolipoprotein E binding(GO:0034187)
0.0	0.0	GO:0015038	glutathione disulfide oxidoreductase activity(GO:0015038)
0.0	0.0	GO:0004803	transposase activity(GO:0004803)
0.0	0.1	GO:0070577	lysine-acetylated histone binding(GO:0070577)
0.0	0.2	GO:0043621	protein self-association(GO:0043621)
0.0	0.1	GO:0003993	acid phosphatase activity(GO:0003993)
0.0	0.1	GO:0004062	aryl sulfotransferase activity(GO:0004062)
0.0	0.1	GO:0008553	hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.0	0.1	GO:0031210	phosphatidylcholine binding(GO:0031210)
0.0	0.0	GO:0017162	aryl hydrocarbon receptor binding(GO:0017162)
0.0	0.0	GO:0048156	tau protein binding(GO:0048156)
0.0	0.1	GO:0001637	G-protein coupled chemoattractant receptor activity(GO:0001637) chemokine receptor activity(GO:0004950)
0.0	0.0	GO:0004465	lipoprotein lipase activity(GO:0004465)
0.0	0.1	GO:0005092	GDP-dissociation inhibitor activity(GO:0005092)
0.0	0.0	GO:0005087	Ran guanyl-nucleotide exchange factor activity(GO:0005087)
0.0	0.0	GO:0034237	protein kinase A regulatory subunit binding(GO:0034237)
0.0	0.1	GO:0051018	protein kinase A binding(GO:0051018)
0.0	0.0	GO:0004449	isocitrate dehydrogenase (NAD+) activity(GO:0004449)
0.0	0.3	GO:0002039	p53 binding(GO:0002039)
0.0	0.1	GO:0099604	calcium-release channel activity(GO:0015278) ligand-gated calcium channel activity(GO:0099604)
0.0	0.0	GO:0032452	histone demethylase activity(GO:0032452)
0.0	0.0	GO:0004321	fatty-acyl-CoA synthase activity(GO:0004321)
0.0	0.2	GO:0050699	WW domain binding(GO:0050699)
0.0	0.0	GO:0035197	siRNA binding(GO:0035197)
0.0	0.0	GO:0043533	inositol 1,3,4,5 tetrakisphosphate binding(GO:0043533)
0.0	0.2	GO:0005484	SNAP receptor activity(GO:0005484)
0.0	0.2	GO:0032393	MHC class I receptor activity(GO:0032393)
0.0	0.3	GO:0001608	G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.0	0.0	GO:0032405	MutLalpha complex binding(GO:0032405)
0.0	0.1	GO:0031701	angiotensin receptor binding(GO:0031701)
0.0	0.0	GO:0003918	DNA topoisomerase type II (ATP-hydrolyzing) activity(GO:0003918) DNA topoisomerase II activity(GO:0061505)
0.0	0.0	GO:0004332	fructose-bisphosphate aldolase activity(GO:0004332)
0.0	0.0	GO:0008327	methyl-CpG binding(GO:0008327)
0.0	0.2	GO:0004129	cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors(GO:0016675) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0	0.1	GO:0008494	translation activator activity(GO:0008494)
0.0	0.6	GO:0008301	DNA binding, bending(GO:0008301)
0.0	0.1	GO:0016668	oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor(GO:0016668)
0.0	0.1	GO:0070411	I-SMAD binding(GO:0070411)
0.0	0.3	GO:0003725	double-stranded RNA binding(GO:0003725)
0.0	0.0	GO:0004607	phosphatidylcholine-sterol O-acyltransferase activity(GO:0004607)
0.0	0.2	GO:0005035	death receptor activity(GO:0005035)
0.0	0.0	GO:0004966	galanin receptor activity(GO:0004966)
0.0	0.1	GO:0043395	heparan sulfate proteoglycan binding(GO:0043395)
0.0	0.0	GO:0016886	ligase activity, forming phosphoric ester bonds(GO:0016886)
0.0	0.1	GO:0048487	beta-tubulin binding(GO:0048487)
0.0	0.1	GO:0004568	chitinase activity(GO:0004568)
0.0	0.2	GO:0043022	ribosome binding(GO:0043022)
0.0	0.1	GO:0030306	ADP-ribosylation factor binding(GO:0030306)
0.0	0.0	GO:0035252	UDP-xylosyltransferase activity(GO:0035252) xylosyltransferase activity(GO:0042285)
0.0	0.0	GO:0034713	type I transforming growth factor beta receptor binding(GO:0034713)
0.0	0.9	GO:0017124	SH3 domain binding(GO:0017124)
0.0	0.1	GO:0008048	calcium sensitive guanylate cyclase activator activity(GO:0008048)
0.0	0.1	GO:0004016	adenylate cyclase activity(GO:0004016)
0.0	0.0	GO:0019958	C-X-C chemokine binding(GO:0019958) interleukin-8 binding(GO:0019959)
0.0	0.0	GO:0004169	dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.0	0.0	GO:0030023	extracellular matrix constituent conferring elasticity(GO:0030023) structural molecule activity conferring elasticity(GO:0097493)
0.0	0.1	GO:0004931	extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
0.0	0.0	GO:0004952	dopamine neurotransmitter receptor activity(GO:0004952)
0.0	0.0	GO:0003701	obsolete RNA polymerase I transcription factor activity(GO:0003701)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	3.5	PID TCR PATHWAY	TCR signaling in naïve CD4+ T cells
0.0	0.1	PID TCR JNK PATHWAY	JNK signaling in the CD4+ TCR pathway
0.0	0.4	SA PTEN PATHWAY	PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.0	0.1	PID HIV NEF PATHWAY	HIV-1 Nef: Negative effector of Fas and TNF-alpha
0.0	0.9	PID GMCSF PATHWAY	GMCSF-mediated signaling events
0.0	1.5	PID NFAT TFPATHWAY	Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0	0.2	ST IL 13 PATHWAY	Interleukin 13 (IL-13) Pathway
0.0	0.1	PID IL12 2PATHWAY	IL12-mediated signaling events
0.0	0.7	PID EPHRINB REV PATHWAY	Ephrin B reverse signaling
0.0	0.0	ST T CELL SIGNAL TRANSDUCTION	T Cell Signal Transduction
0.0	0.2	SA FAS SIGNALING	The TNF-type receptor Fas induces apoptosis on ligand binding.
0.0	0.1	PID TCR RAS PATHWAY	Ras signaling in the CD4+ TCR pathway
0.0	0.3	PID SMAD2 3PATHWAY	Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0	0.1	PID FAS PATHWAY	FAS (CD95) signaling pathway
0.0	0.3	SA MMP CYTOKINE CONNECTION	Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0	0.1	PID RANBP2 PATHWAY	Sumoylation by RanBP2 regulates transcriptional repression
0.0	0.0	ST P38 MAPK PATHWAY	p38 MAPK Pathway
0.0	0.2	PID NFKAPPAB ATYPICAL PATHWAY	Atypical NF-kappaB pathway
0.0	0.2	SA G1 AND S PHASES	Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition.
0.0	0.8	PID AR TF PATHWAY	Regulation of Androgen receptor activity
0.0	0.0	PID ERBB4 PATHWAY	ErbB4 signaling events
0.0	0.4	PID EPHA FWDPATHWAY	EPHA forward signaling
0.0	1.0	PID BETA CATENIN NUC PATHWAY	Regulation of nuclear beta catenin signaling and target gene transcription
0.0	0.1	ST PAC1 RECEPTOR PATHWAY	PAC1 Receptor Pathway
0.0	0.2	PID IL2 STAT5 PATHWAY	IL2 signaling events mediated by STAT5
0.0	0.1	PID IL2 PI3K PATHWAY	IL2 signaling events mediated by PI3K
0.0	0.3	PID BCR 5PATHWAY	BCR signaling pathway
0.0	0.3	PID TOLL ENDOGENOUS PATHWAY	Endogenous TLR signaling
0.0	0.3	PID IL8 CXCR2 PATHWAY	IL8- and CXCR2-mediated signaling events
0.0	0.0	SA CASPASE CASCADE	Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.0	0.4	PID NFAT 3PATHWAY	Role of Calcineurin-dependent NFAT signaling in lymphocytes
0.0	0.3	PID CD8 TCR DOWNSTREAM PATHWAY	Downstream signaling in naïve CD8+ T cells
0.0	0.3	PID CDC42 REG PATHWAY	Regulation of CDC42 activity
0.0	0.0	ST GRANULE CELL SURVIVAL PATHWAY	Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway.
0.0	0.1	PID IL12 STAT4 PATHWAY	IL12 signaling mediated by STAT4
0.0	0.2	PID MYC PATHWAY	C-MYC pathway
0.0	0.0	PID ERBB NETWORK PATHWAY	ErbB receptor signaling network
0.0	0.1	PID TRAIL PATHWAY	TRAIL signaling pathway
0.0	0.0	PID CXCR3 PATHWAY	CXCR3-mediated signaling events
0.0	0.1	PID CD40 PATHWAY	CD40/CD40L signaling
0.0	0.4	PID AURORA B PATHWAY	Aurora B signaling
0.0	0.1	ST TUMOR NECROSIS FACTOR PATHWAY	Tumor Necrosis Factor Pathway.
0.0	0.0	PID NFKAPPAB CANONICAL PATHWAY	Canonical NF-kappaB pathway
0.0	0.0	ST B CELL ANTIGEN RECEPTOR	B Cell Antigen Receptor
0.0	0.2	PID FCER1 PATHWAY	Fc-epsilon receptor I signaling in mast cells
0.0	0.3	PID CERAMIDE PATHWAY	Ceramide signaling pathway
0.0	0.1	ST INTERLEUKIN 4 PATHWAY	Interleukin 4 (IL-4) Pathway
0.0	0.1	PID AURORA A PATHWAY	Aurora A signaling
0.0	0.1	PID PI3KCI PATHWAY	Class I PI3K signaling events
0.0	0.0	ST JAK STAT PATHWAY	Jak-STAT Pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.5	REACTOME CD28 DEPENDENT VAV1 PATHWAY	Genes involved in CD28 dependent Vav1 pathway
0.1	0.2	REACTOME BINDING AND ENTRY OF HIV VIRION	Genes involved in Binding and entry of HIV virion
0.1	0.9	REACTOME RAP1 SIGNALLING	Genes involved in Rap1 signalling
0.1	0.8	REACTOME GENERATION OF SECOND MESSENGER MOLECULES	Genes involved in Generation of second messenger molecules
0.0	0.7	REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS	Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.0	0.6	REACTOME N GLYCAN ANTENNAE ELONGATION	Genes involved in N-Glycan antennae elongation
0.0	0.3	REACTOME ACTIVATION OF RAC	Genes involved in Activation of Rac
0.0	1.0	REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS	Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.0	0.4	REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS	Genes involved in Signal regulatory protein (SIRP) family interactions
0.0	0.3	REACTOME IL 7 SIGNALING	Genes involved in Interleukin-7 signaling
0.0	0.4	REACTOME DOWNSTREAM TCR SIGNALING	Genes involved in Downstream TCR signaling
0.0	0.9	REACTOME GLYCOSPHINGOLIPID METABOLISM	Genes involved in Glycosphingolipid metabolism
0.0	0.2	REACTOME RAS ACTIVATION UOPN CA2 INFUX THROUGH NMDA RECEPTOR	Genes involved in Ras activation uopn Ca2+ infux through NMDA receptor
0.0	0.2	REACTOME REGULATION OF KIT SIGNALING	Genes involved in Regulation of KIT signaling
0.0	0.3	REACTOME CTLA4 INHIBITORY SIGNALING	Genes involved in CTLA4 inhibitory signaling
0.0	0.2	REACTOME ABORTIVE ELONGATION OF HIV1 TRANSCRIPT IN THE ABSENCE OF TAT	Genes involved in Abortive elongation of HIV-1 transcript in the absence of Tat
0.0	0.1	REACTOME SPRY REGULATION OF FGF SIGNALING	Genes involved in Spry regulation of FGF signaling
0.0	1.1	REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL	Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0	0.4	REACTOME REGULATORY RNA PATHWAYS	Genes involved in Regulatory RNA pathways
0.0	0.1	REACTOME ER PHAGOSOME PATHWAY	Genes involved in ER-Phagosome pathway
0.0	0.2	REACTOME NFKB ACTIVATION THROUGH FADD RIP1 PATHWAY MEDIATED BY CASPASE 8 AND10	Genes involved in NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10
0.0	0.2	REACTOME TRAF3 DEPENDENT IRF ACTIVATION PATHWAY	Genes involved in TRAF3-dependent IRF activation pathway
0.0	0.5	REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE	Genes involved in Synthesis of PIPs at the plasma membrane
0.0	0.2	REACTOME IL RECEPTOR SHC SIGNALING	Genes involved in Interleukin receptor SHC signaling
0.0	0.8	REACTOME INTERFERON GAMMA SIGNALING	Genes involved in Interferon gamma signaling
0.0	0.2	REACTOME ASSOCIATION OF LICENSING FACTORS WITH THE PRE REPLICATIVE COMPLEX	Genes involved in Association of licensing factors with the pre-replicative complex
0.0	0.3	REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY	Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.0	0.3	REACTOME THE ROLE OF NEF IN HIV1 REPLICATION AND DISEASE PATHOGENESIS	Genes involved in The role of Nef in HIV-1 replication and disease pathogenesis
0.0	0.1	REACTOME SIGNALING BY SCF KIT	Genes involved in Signaling by SCF-KIT
0.0	0.0	REACTOME RETROGRADE NEUROTROPHIN SIGNALLING	Genes involved in Retrograde neurotrophin signalling
0.0	0.2	REACTOME EICOSANOID LIGAND BINDING RECEPTORS	Genes involved in Eicosanoid ligand-binding receptors
0.0	0.1	REACTOME N GLYCAN ANTENNAE ELONGATION IN THE MEDIAL TRANS GOLGI	Genes involved in N-glycan antennae elongation in the medial/trans-Golgi
0.0	0.3	REACTOME CITRIC ACID CYCLE TCA CYCLE	Genes involved in Citric acid cycle (TCA cycle)
0.0	0.2	REACTOME TRANSPORT TO THE GOLGI AND SUBSEQUENT MODIFICATION	Genes involved in Transport to the Golgi and subsequent modification
0.0	0.5	REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION	Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.0	0.2	REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS	Genes involved in Proteolytic cleavage of SNARE complex proteins
0.0	1.1	REACTOME RESPIRATORY ELECTRON TRANSPORT ATP SYNTHESIS BY CHEMIOSMOTIC COUPLING AND HEAT PRODUCTION BY UNCOUPLING PROTEINS	Genes involved in Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins.
0.0	0.2	REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT	Genes involved in Chylomicron-mediated lipid transport
0.0	0.1	REACTOME ETHANOL OXIDATION	Genes involved in Ethanol oxidation
0.0	0.1	REACTOME CTNNB1 PHOSPHORYLATION CASCADE	Genes involved in Beta-catenin phosphorylation cascade
0.0	0.4	REACTOME ACTIVATION OF ATR IN RESPONSE TO REPLICATION STRESS	Genes involved in Activation of ATR in response to replication stress
0.0	0.2	REACTOME COSTIMULATION BY THE CD28 FAMILY	Genes involved in Costimulation by the CD28 family
0.0	0.4	REACTOME TRANSPORT OF RIBONUCLEOPROTEINS INTO THE HOST NUCLEUS	Genes involved in Transport of Ribonucleoproteins into the Host Nucleus
0.0	0.0	REACTOME REGULATION OF SIGNALING BY CBL	Genes involved in Regulation of signaling by CBL
0.0	0.2	REACTOME REGULATION OF COMPLEMENT CASCADE	Genes involved in Regulation of Complement cascade
0.0	0.3	REACTOME RECYCLING PATHWAY OF L1	Genes involved in Recycling pathway of L1
0.0	0.1	REACTOME TRAF6 MEDIATED NFKB ACTIVATION	Genes involved in TRAF6 mediated NF-kB activation
0.0	0.1	REACTOME GRB2 SOS PROVIDES LINKAGE TO MAPK SIGNALING FOR INTERGRINS	Genes involved in GRB2:SOS provides linkage to MAPK signaling for Intergrins
0.0	0.1	REACTOME ABACAVIR TRANSPORT AND METABOLISM	Genes involved in Abacavir transport and metabolism
0.0	0.3	REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE	Genes involved in Sema4D induced cell migration and growth-cone collapse
0.0	0.1	REACTOME ACTIVATION OF BH3 ONLY PROTEINS	Genes involved in Activation of BH3-only proteins
0.0	0.2	REACTOME PIP3 ACTIVATES AKT SIGNALING	Genes involved in PIP3 activates AKT signaling
0.0	0.1	REACTOME PKB MEDIATED EVENTS	Genes involved in PKB-mediated events
0.0	0.3	REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS	Genes involved in Apoptotic cleavage of cellular proteins
0.0	0.2	REACTOME METABOLISM OF NON CODING RNA	Genes involved in Metabolism of non-coding RNA
0.0	0.1	REACTOME SIGNALING BY ROBO RECEPTOR	Genes involved in Signaling by Robo receptor
0.0	0.1	REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY	Genes involved in Adenylate cyclase activating pathway
0.0	0.2	REACTOME FANCONI ANEMIA PATHWAY	Genes involved in Fanconi Anemia pathway
0.0	0.2	REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING	Genes involved in Downregulation of TGF-beta receptor signaling
0.0	0.2	REACTOME FORMATION OF INCISION COMPLEX IN GG NER	Genes involved in Formation of incision complex in GG-NER
0.0	0.1	REACTOME HIGHLY CALCIUM PERMEABLE POSTSYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS	Genes involved in Highly calcium permeable postsynaptic nicotinic acetylcholine receptors
0.0	0.1	REACTOME THE NLRP3 INFLAMMASOME	Genes involved in The NLRP3 inflammasome
0.0	0.2	REACTOME REGULATION OF IFNA SIGNALING	Genes involved in Regulation of IFNA signaling
0.0	0.2	REACTOME ENERGY DEPENDENT REGULATION OF MTOR BY LKB1 AMPK	Genes involved in Energy dependent regulation of mTOR by LKB1-AMPK
0.0	0.1	REACTOME INTERACTIONS OF VPR WITH HOST CELLULAR PROTEINS	Genes involved in Interactions of Vpr with host cellular proteins
0.0	0.2	REACTOME KINESINS	Genes involved in Kinesins
0.0	0.0	REACTOME ACTIVATION OF NMDA RECEPTOR UPON GLUTAMATE BINDING AND POSTSYNAPTIC EVENTS	Genes involved in Activation of NMDA receptor upon glutamate binding and postsynaptic events

Results for PKNOX1_TGIF2

Z-value: 1.00

Motif logo

Transcription factors associated with PKNOX1_TGIF2

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

Activity of the PKNOX1_TGIF2 motif across conditions

Conditions sorted by the z-value of the PKNOX1_TGIF2 motif activity

Top target CREs of the motif:

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of PKNOX1_TGIF2

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category:

Gene overrepresentation in curated gene sets: canonical pathways category:

Gene overrepresentation in curated gene sets: REACTOME pathways category: