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ENCODE: H3K4me1 ChIP-Seq of primary human cells
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Results for PKNOX2

Z-value: 0.90

Motif logo

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Transcription factors associated with PKNOX2

Gene Symbol Gene ID Gene Info
PKNOX2
ENSG00000165495.11 PBX/knotted 1 homeobox 2

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE Gene Distance Association probability Pearson corr. coef. P-value Plot
chr11_125046475_125046626PKNOX275330.1589880.771.4e-02Click!
chr11_125234303_125234454PKNOX2342230.1610450.752.0e-02Click!
chr11_125035327_125035515PKNOX27710.4346800.693.8e-02Click!
chr11_125246240_125246391PKNOX2461600.1324560.675.0e-02Click!
chr11_125047215_125047366PKNOX267930.1618390.665.3e-02Click!

Activity of the PKNOX2 motif across conditions

Conditions sorted by the z-value of the PKNOX2 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE) Target Score Top associated gene Gene Info Distance of CRE to TSS CRE/Gene association probability
chr13_50144464_50144942 0.41 RCBTB1
 regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 1
 3244
 0.28
chr10_77793698_77793895 0.36 ENSG00000221232
 .
 93273
 0.09
chr7_30266553_30266704 0.35 ZNRF2
 zinc and ring finger 2
 57295
 0.1
chr8_62621150_62621301 0.35 ASPH
 aspartate beta-hydroxylase
 5859
 0.24
chr9_37998944_37999499 0.35 ENSG00000251745
 .
 62456
 0.11
chr14_103452871_103453087 0.34 CDC42BPB
 CDC42 binding protein kinase beta (DMPK-like)
 18110
 0.17
chr2_196440572_196441282 0.31 SLC39A10
 solute carrier family 39 (zinc transporter), member 10
 226
 0.96
chr6_82732173_82732324 0.30 ENSG00000223044
 .
 187909
 0.03
chr1_66258245_66258475 0.29 PDE4B
 phosphodiesterase 4B, cAMP-specific
 163
 0.97
chr5_169380510_169380661 0.29 FAM196B
 family with sequence similarity 196, member B
 27159
 0.22
chr6_13484408_13484559 0.28 AL583828.1
1932
 0.24
chr6_36630267_36630418 0.28 ENSG00000251864
 .
 10273
 0.14
chr11_94411215_94411366 0.28 AMOTL1
 angiomotin like 1
 28307
 0.18
chr11_117812434_117812585 0.28 TMPRSS13
 transmembrane protease, serine 13
 12335
 0.17
chr11_34225524_34225701 0.27 ENSG00000201867
 .
 14891
 0.26
chr2_232164549_232164700 0.27 ARMC9
 armadillo repeat containing 9
 29379
 0.17
chrX_153713483_153713883 0.27 UBL4A
 ubiquitin-like 4A
 1271
 0.2
chr6_2798735_2799020 0.27 WRNIP1
 Werner helicase interacting protein 1
 29870
 0.15
chr22_38618392_38618543 0.27 RP1-5O6.5
8859
 0.11
chr11_128773402_128773673 0.27 C11orf45
 chromosome 11 open reading frame 45
 2055
 0.28
chr4_157692338_157692515 0.26 RP11-154F14.2
70085
 0.11
chr4_55685762_55685928 0.26 KIT
 v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
 161760
 0.04
chr1_64471981_64472261 0.26 ENSG00000207190
 .
 22551
 0.22
chr9_113681977_113682128 0.26 ENSG00000207401
 .
 14634
 0.21
chr7_116166986_116167137 0.26 CAV1
 caveolin 1, caveolae protein, 22kDa
 714
 0.63
chr17_36981173_36981324 0.25 CWC25
 CWC25 spliceosome-associated protein homolog (S. cerevisiae)
 320
 0.67
chr7_66205180_66205331 0.25 RP11-792A8.4
117
 0.71
chr10_73532418_73532814 0.25 C10orf54
 chromosome 10 open reading frame 54
 639
 0.72
chr20_22738676_22738827 0.25 ENSG00000265151
 .
 24812
 0.26
chr2_237657369_237658039 0.25 ACKR3
 atypical chemokine receptor 3
 179420
 0.03
chr11_18344519_18344871 0.24 GTF2H1
 general transcription factor IIH, polypeptide 1, 62kDa
 552
 0.55
chr5_115827166_115827708 0.24 SEMA6A
 sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A
 13064
 0.24
chr16_68693085_68693236 0.24 RP11-615I2.2
13089
 0.13
chr16_56945673_56945825 0.24 HERPUD1
 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
 20211
 0.11
chr21_38903444_38903595 0.24 AP001421.1
 Uncharacterized protein
 14779
 0.24
chr2_47401652_47401939 0.24 CALM2
 calmodulin 2 (phosphorylase kinase, delta)
 1855
 0.37
chr7_23736580_23736769 0.24 STK31
 serine/threonine kinase 31
 13112
 0.16
chr17_55521431_55521582 0.24 ENSG00000263902
 .
 31944
 0.2
chr11_78139062_78139213 0.24 GAB2
 GRB2-associated binding protein 2
 9743
 0.18
chr20_43968652_43968803 0.23 SDC4
 syndecan 4
 8337
 0.12
chr12_52355616_52356045 0.23 ACVR1B
 activin A receptor, type IB
 8666
 0.15
chr19_48836940_48837114 0.23 EMP3
 epithelial membrane protein 3
 8162
 0.11
chr8_31497191_31497379 0.23 NRG1
 neuregulin 1
 14
 0.99
chr9_137687858_137688009 0.23 COL5A1
 collagen, type V, alpha 1
 28557
 0.09
chr10_3797419_3797677 0.23 RP11-184A2.3
4289
 0.25
chr9_130308458_130308879 0.23 FAM129B
 family with sequence similarity 129, member B
 22699
 0.15
chr3_70102890_70103041 0.23 MITF
 microphthalmia-associated transcription factor
 117091
 0.06
chr2_16674927_16675078 0.23 AC104623.2
29442
 0.25
chr3_194964658_194964809 0.23 XXYLT1
 xyloside xylosyltransferase 1
 3916
 0.21
chr15_80354165_80354676 0.23 ZFAND6
 zinc finger, AN1-type domain 6
 1654
 0.44
chr6_85483668_85483897 0.23 TBX18
 T-box 18
 9545
 0.3
chr2_110402358_110402509 0.23 SOWAHC
 sosondowah ankyrin repeat domain family member C
 30522
 0.16
chr4_103414906_103415100 0.23 AF213884.2
7473
 0.22
chr17_39650766_39650917 0.22 KRT36
 keratin 36
 2043
 0.14
chr2_241525444_241525595 0.22 CAPN10-AS1
 CAPN10 antisense RNA 1 (head to head)
 597
 0.4
chr5_173960206_173960357 0.22 MSX2
 msh homeobox 2
 191255
 0.03
chr2_105997925_105998220 0.22 AC012360.6
7522
 0.19
chr5_14178416_14178612 0.22 TRIO
 trio Rho guanine nucleotide exchange factor
 5393
 0.35
chr2_65605561_65605712 0.22 SPRED2
 sprouty-related, EVH1 domain containing 2
 752
 0.66
chr2_65132087_65132267 0.22 ENSG00000244534
 .
 2095
 0.28
chr12_70329549_70329700 0.22 MYRFL
 myelin regulatory factor-like
 3308
 0.29
chr20_43150138_43150289 0.22 SERINC3
 serine incorporator 3
 438
 0.78
chr2_102371116_102371522 0.22 MAP4K4
 mitogen-activated protein kinase kinase kinase kinase 4
 42407
 0.2
chr10_3791986_3792257 0.22 RP11-184A2.3
1138
 0.55
chr9_127058687_127058838 0.22 NEK6
 NIMA-related kinase 6
 3502
 0.23
chr15_68996933_68997188 0.21 CORO2B
 coronin, actin binding protein, 2B
 72733
 0.11
chr11_106353555_106353706 0.21 RP11-680E19.1
218588
 0.02
chr1_193073520_193073675 0.21 GLRX2
 glutaredoxin 2
 964
 0.46
chr8_81209498_81209699 0.21 ENSG00000206649
 .
 19706
 0.21
chr4_183065081_183065265 0.21 AC108142.1
132
 0.85
chr22_18345511_18345662 0.21 MICAL3
 microtubule associated monooxygenase, calponin and LIM domain containing 3
 30820
 0.17
chr12_95597054_95597379 0.21 FGD6
 FYVE, RhoGEF and PH domain containing 6
 13939
 0.18
chr5_157171669_157172078 0.21 LSM11
 LSM11, U7 small nuclear RNA associated
 1170
 0.4
chr6_19838520_19838671 0.21 RP1-167F1.2
716
 0.55
chr7_33894333_33894504 0.21 BMPER
 BMP binding endothelial regulator
 50105
 0.18
chr7_45040547_45040957 0.21 CCM2
 cerebral cavernous malformation 2
 965
 0.47
chr17_17642246_17642462 0.21 RAI1-AS1
 RAI1 antisense RNA 1
 31781
 0.12
chr1_234754493_234754778 0.21 IRF2BP2
 interferon regulatory factor 2 binding protein 2
 9364
 0.19
chr8_145655573_145655724 0.20 VPS28
 vacuolar protein sorting 28 homolog (S. cerevisiae)
 1717
 0.13
chr1_44154355_44154570 0.20 KDM4A-AS1
 KDM4A antisense RNA 1
 15678
 0.14
chr7_92255177_92255408 0.20 FAM133B
 family with sequence similarity 133, member B
 35584
 0.17
chr6_69344527_69344720 0.20 RP3-525N10.2
231
 0.82
chr2_149401069_149401839 0.20 EPC2
 enhancer of polycomb homolog 2 (Drosophila)
 555
 0.86
chr12_96487410_96487841 0.20 ENSG00000266889
 .
 8402
 0.2
chr1_78561687_78561966 0.19 ENSG00000202263
 .
 1227
 0.46
chr1_55370512_55370663 0.19 RP11-67L3.4
17182
 0.14
chr5_4197921_4198072 0.19 CTD-2012M11.3
597694
 0.0
chr22_47201366_47201517 0.19 TBC1D22A
 TBC1 domain family, member 22A
 31617
 0.16
chr2_62702609_62702952 0.19 ENSG00000241625
 .
 15533
 0.23
chr22_33113641_33113825 0.19 LL22NC01-116C6.1
65430
 0.11
chr20_43966692_43966843 0.19 SDC4
 syndecan 4
 10297
 0.12
chr5_145297127_145297278 0.19 SH3RF2
 SH3 domain containing ring finger 2
 18940
 0.22
chr1_108584195_108584461 0.19 ENSG00000264753
 .
 22935
 0.22
chr5_58999641_58999792 0.19 ENSG00000202601
 .
 187
 0.97
chr10_79339026_79339177 0.19 ENSG00000199592
 .
 7706
 0.27
chr2_216973110_216973261 0.19 XRCC5
 X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining)
 835
 0.62
chr12_6960691_6960910 0.19 CDCA3
 cell division cycle associated 3
 367
 0.48
chr8_102120279_102120548 0.19 ENSG00000202360
 .
 29774
 0.2
chr2_217237352_217237503 0.19 MARCH4
 membrane-associated ring finger (C3HC4) 4, E3 ubiquitin protein ligase
 677
 0.66
chr1_44266850_44267001 0.19 ST3GAL3
 ST3 beta-galactoside alpha-2,3-sialyltransferase 3
 64991
 0.08
chr6_71817462_71817736 0.19 ENSG00000221345
 .
 19209
 0.25
chr1_22463906_22464057 0.19 WNT4
 wingless-type MMTV integration site family, member 4
 5478
 0.23
chr17_27419224_27419375 0.19 TIAF1
 TGFB1-induced anti-apoptotic factor 1
 762
 0.58
chr6_158460041_158460192 0.18 SYNJ2
 synaptojanin 2
 21619
 0.18
chr5_106907227_106907905 0.18 EFNA5
 ephrin-A5
 98762
 0.09
chr5_137876739_137877439 0.18 ETF1
 eukaryotic translation termination factor 1
 311
 0.86
chr7_66146609_66146762 0.18 RP4-756H11.3
27112
 0.16
chr22_50732960_50733111 0.18 PLXNB2
 plexin B2
 5045
 0.1
chr6_6814488_6814639 0.18 ENSG00000240936
 .
 124567
 0.06
chr2_172654761_172655200 0.18 AC068039.4
24988
 0.19
chr4_55779949_55780100 0.18 ENSG00000264332
 .
 97075
 0.07
chr1_7462341_7462492 0.18 RP3-453P22.2
12602
 0.21
chr1_10958636_10958867 0.18 C1orf127
 chromosome 1 open reading frame 127
 49176
 0.12
chr11_128779050_128779201 0.18 KCNJ5
 potassium inwardly-rectifying channel, subfamily J, member 5
 1954
 0.27
chr5_153569731_153569882 0.18 GALNT10
 UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 10 (GalNAc-T10)
 484
 0.86
chr1_201463290_201463773 0.18 CSRP1
 cysteine and glycine-rich protein 1
 2170
 0.26
chr7_21982587_21982783 0.18 CDCA7L
 cell division cycle associated 7-like
 1806
 0.5
chr3_132349120_132349271 0.18 UBA5
 ubiquitin-like modifier activating enzyme 5
 24095
 0.16
chr7_2800167_2800318 0.18 GNA12
 guanine nucleotide binding protein (G protein) alpha 12
 2532
 0.35
chr10_81024445_81024596 0.18 ZMIZ1
 zinc finger, MIZ-type containing 1
 41455
 0.18
chr22_31884469_31885148 0.18 EIF4ENIF1
 eukaryotic translation initiation factor 4E nuclear import factor 1
 77
 0.96
chr9_115534398_115534820 0.18 SNX30
 sorting nexin family member 30
 21491
 0.18
chr2_118863719_118863870 0.18 INSIG2
 insulin induced gene 2
 17744
 0.23
chr5_135347344_135347609 0.18 TGFBI
 transforming growth factor, beta-induced, 68kDa
 17108
 0.2
chr22_43540224_43540381 0.18 MCAT
 malonyl CoA:ACP acyltransferase (mitochondrial)
 902
 0.5
chr9_14183184_14183335 0.18 NFIB
 nuclear factor I/B
 2462
 0.44
chr13_92002817_92003060 0.17 ENSG00000215417
 .
 59
 0.99
chr7_32303689_32303840 0.17 PDE1C
 phosphodiesterase 1C, calmodulin-dependent 70kDa
 35177
 0.24
chr16_11593490_11593706 0.17 CTD-3088G3.8
 Protein LOC388210
 7987
 0.15
chr10_131129546_131129832 0.17 MGMT
 O-6-methylguanine-DNA methyltransferase
 135759
 0.05
chr3_111400647_111400798 0.17 PLCXD2-AS1
 PLCXD2 antisense RNA 1
 4442
 0.23
chr1_157565778_157565929 0.17 FCRL4
 Fc receptor-like 4
 2017
 0.38
chr13_77568293_77568444 0.17 CLN5
 ceroid-lipofuscinosis, neuronal 5
 3573
 0.23
chr13_60026420_60026571 0.17 ENSG00000239003
 .
 27709
 0.27
chr5_14745440_14745591 0.17 ANKH
 ANKH inorganic pyrophosphate transport regulator
 5805
 0.26
chr22_28107190_28107341 0.17 RP11-375H17.1
5203
 0.32
chr4_6992668_6992852 0.17 TBC1D14
 TBC1 domain family, member 14
 3871
 0.13
chr5_126111255_126111406 0.17 LMNB1
 lamin B1
 1510
 0.46
chr2_68937791_68938087 0.17 ARHGAP25
 Rho GTPase activating protein 25
 305
 0.93
chr1_207262289_207262674 0.17 C4BPB
 complement component 4 binding protein, beta
 77
 0.96
chr15_59463059_59463212 0.17 ENSG00000253030
 .
 326
 0.81
chr13_52748916_52749067 0.17 NEK3
 NIMA-related kinase 3
 14995
 0.18
chr20_52421695_52421846 0.17 AC005220.3
134929
 0.05
chr1_221932844_221932995 0.17 DUSP10
 dual specificity phosphatase 10
 17401
 0.28
chr2_227050336_227050624 0.17 ENSG00000263363
 .
 473029
 0.01
chr11_104941248_104941509 0.17 CARD16
 caspase recruitment domain family, member 16
 25275
 0.15
chr17_26897925_26898076 0.17 PIGS
 phosphatidylinositol glycan anchor biosynthesis, class S
 546
 0.49
chr1_27626340_27626505 0.17 TMEM222
 transmembrane protein 222
 22229
 0.11
chr15_52069126_52069277 0.17 CTD-2308G16.1
24519
 0.12
chr7_92253875_92254026 0.17 FAM133B
 family with sequence similarity 133, member B
 34242
 0.17
chr9_74384006_74384157 0.17 TMEM2
 transmembrane protein 2
 281
 0.95
chr12_90267768_90267973 0.17 ENSG00000252823
 .
 120034
 0.06
chr5_40401420_40402168 0.17 ENSG00000265615
 .
 81374
 0.11
chr2_38151916_38152120 0.17 RMDN2
 regulator of microtubule dynamics 2
 444
 0.89
chr10_101686899_101687132 0.17 DNMBP-AS1
 DNMBP antisense RNA 1
 49
 0.98
chr12_98812168_98812319 0.17 ENSG00000201296
 .
 427
 0.88
chr8_21967356_21967589 0.17 NUDT18
 nudix (nucleoside diphosphate linked moiety X)-type motif 18
 540
 0.64
chr14_69735167_69735318 0.17 GALNT16
 UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 16
 8234
 0.24
chr6_82854761_82854912 0.17 ENSG00000223044
 .
 65321
 0.14
chr5_53510644_53510880 0.16 ARL15
 ADP-ribosylation factor-like 15
 95641
 0.08
chr3_39276693_39276844 0.16 XIRP1
 xin actin-binding repeat containing 1
 42681
 0.13
chr20_50312015_50312166 0.16 ATP9A
 ATPase, class II, type 9A
 72777
 0.11
chr17_66179467_66179660 0.16 LRRC37A16P
 leucine rich repeat containing 37, member A16, pseudogene
 30954
 0.15
chr14_78058344_78058495 0.16 SPTLC2
 serine palmitoyltransferase, long chain base subunit 2
 5245
 0.21
chr5_96170923_96171074 0.16 ERAP1
 endoplasmic reticulum aminopeptidase 1
 27195
 0.12
chr8_24153597_24153748 0.16 ADAM28
 ADAM metallopeptidase domain 28
 2048
 0.42
chr21_16249905_16250056 0.16 AF127577.8
40875
 0.18
chr6_7153073_7153464 0.16 RREB1
 ras responsive element binding protein 1
 13790
 0.19
chr3_71111992_71112428 0.16 FOXP1
 forkhead box P1
 1867
 0.51
chr1_192670704_192670864 0.16 RGS13
 regulator of G-protein signaling 13
 65502
 0.12
chr9_95500415_95500727 0.16 BICD2
 bicaudal D homolog 2 (Drosophila)
 26523
 0.17
chr4_74975080_74975254 0.16 CXCL2
 chemokine (C-X-C motif) ligand 2
 10157
 0.16
chr1_43203800_43204078 0.16 CLDN19
 claudin 19
 1872
 0.26
chr11_95770595_95770746 0.16 MTMR2
 myotubularin related protein 2
 113211
 0.07
chr13_53419930_53420188 0.16 PCDH8
 protocadherin 8
 2581
 0.35
chr2_39777891_39778042 0.16 AC007246.3
32150
 0.21
chr17_76374368_76374519 0.16 PGS1
 phosphatidylglycerophosphate synthase 1
 278
 0.87
chr3_48724801_48724952 0.16 NCKIPSD
 NCK interacting protein with SH3 domain
 1079
 0.35
chr11_46936507_46936803 0.16 LRP4
 low density lipoprotein receptor-related protein 4
 3518
 0.23
chr9_92445809_92446274 0.16 GADD45G
 growth arrest and DNA-damage-inducible, gamma
 226088
 0.02
chr1_61606862_61607139 0.16 RP4-802A10.1
16595
 0.23
chr8_144682971_144683122 0.16 EEF1D
 eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein)
 1335
 0.19
chr8_96902024_96902175 0.16 ENSG00000223297
 .
 210956
 0.02
chr3_194838476_194838628 0.16 XXYLT1
 xyloside xylosyltransferase 1
 4369
 0.17
chr12_124451409_124451560 0.16 RP11-214K3.21
308
 0.71
chr7_104908892_104909338 0.16 SRPK2
 SRSF protein kinase 2
 347
 0.9
chr17_39094006_39094157 0.16 KRT23
 keratin 23 (histone deacetylase inducible)
 343
 0.76
chr6_110849182_110849360 0.16 CTA-331P3.1
50161
 0.13
chr13_45816557_45816749 0.16 KCTD4
 potassium channel tetramerization domain containing 4
 41478
 0.12
chr8_37468731_37468882 0.16 ENSG00000223215
 .
 57610
 0.1
chr1_33829610_33829761 0.16 PHC2
 polyhomeotic homolog 2 (Drosophila)
 8875
 0.14
chr8_9791123_9791323 0.16 ENSG00000238496
 .
 1890
 0.37
chr2_113881955_113882155 0.15 IL1RN
 interleukin 1 receptor antagonist
 3083
 0.19
chr7_139510118_139510269 0.15 TBXAS1
 thromboxane A synthase 1 (platelet)
 18759
 0.22
chr16_70731287_70731500 0.15 VAC14
 Vac14 homolog (S. cerevisiae)
 1897
 0.26
chr4_170180392_170180649 0.15 SH3RF1
 SH3 domain containing ring finger 1
 10588
 0.27
chr8_32776162_32776330 0.15 ENSG00000212407
 .
 7130
 0.33
chr3_45595189_45595741 0.15 ENSG00000251927
 .
 38282
 0.14
chr2_57825828_57826109 0.15 ENSG00000212168
 .
 54298
 0.18
chr4_157870050_157870201 0.15 PDGFC
 platelet derived growth factor C
 21930
 0.21

Histogram of CRE-TSS distances for CREs targeted by :

Histogram of

Rank distribution of CRE target scores:

Histogram of target CRE score.

Distribution of target CREs across different genomic regions:

Weighted Piechart of Weighted Piechart of Weighted Piechart of

Network of associatons between targets according to the STRING database.

First level regulatory network of PKNOX2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.1 GO:0002043 blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:0002043)
0.0 0.2 GO:0043497 regulation of protein heterodimerization activity(GO:0043497)
0.0 0.1 GO:0001821 histamine secretion(GO:0001821)
0.0 0.3 GO:0006198 cAMP catabolic process(GO:0006198)
0.0 0.1 GO:0016080 synaptic vesicle targeting(GO:0016080)
0.0 0.1 GO:0061154 endothelial tube morphogenesis(GO:0061154)
0.0 0.1 GO:0032959 inositol trisphosphate biosynthetic process(GO:0032959)
0.0 0.1 GO:0032516 positive regulation of phosphoprotein phosphatase activity(GO:0032516)
0.0 0.1 GO:0031946 regulation of glucocorticoid biosynthetic process(GO:0031946)
0.0 0.1 GO:0015816 glycine transport(GO:0015816)
0.0 0.1 GO:0001574 ganglioside biosynthetic process(GO:0001574)
0.0 0.1 GO:0072010 renal filtration cell differentiation(GO:0061318) glomerular epithelium development(GO:0072010) glomerular visceral epithelial cell differentiation(GO:0072112) glomerular epithelial cell differentiation(GO:0072311)
0.0 0.1 GO:0048643 positive regulation of skeletal muscle tissue development(GO:0048643)
0.0 0.1 GO:0021535 cell migration in hindbrain(GO:0021535)
0.0 0.1 GO:0072698 protein localization to cytoskeleton(GO:0044380) protein localization to microtubule cytoskeleton(GO:0072698)
0.0 0.1 GO:0071816 protein insertion into ER membrane(GO:0045048) tail-anchored membrane protein insertion into ER membrane(GO:0071816)
0.0 0.1 GO:0046501 protoporphyrinogen IX metabolic process(GO:0046501)
0.0 0.2 GO:0007185 transmembrane receptor protein tyrosine phosphatase signaling pathway(GO:0007185)
0.0 0.1 GO:0018094 protein polyglycylation(GO:0018094)
0.0 0.1 GO:0015015 heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.0 0.1 GO:0021819 layer formation in cerebral cortex(GO:0021819)
0.0 0.1 GO:0030011 maintenance of cell polarity(GO:0030011)
0.0 0.2 GO:0016255 attachment of GPI anchor to protein(GO:0016255)
0.0 0.1 GO:0042532 negative regulation of tyrosine phosphorylation of STAT protein(GO:0042532)
0.0 0.1 GO:0006549 isoleucine metabolic process(GO:0006549)
0.0 0.1 GO:0060218 hematopoietic stem cell differentiation(GO:0060218)
0.0 0.1 GO:0034501 protein localization to kinetochore(GO:0034501)
0.0 0.2 GO:0032986 nucleosome disassembly(GO:0006337) chromatin disassembly(GO:0031498) protein-DNA complex disassembly(GO:0032986)
0.0 0.1 GO:0048702 embryonic neurocranium morphogenesis(GO:0048702)
0.0 0.1 GO:0001554 luteolysis(GO:0001554)
0.0 0.1 GO:0071501 response to sterol depletion(GO:0006991) SREBP signaling pathway(GO:0032933) cellular response to sterol depletion(GO:0071501)
0.0 0.1 GO:0002328 pro-B cell differentiation(GO:0002328)
0.0 0.1 GO:0019227 neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870)
0.0 0.1 GO:0008215 spermine metabolic process(GO:0008215)
0.0 0.1 GO:0008054 negative regulation of cyclin-dependent protein serine/threonine kinase by cyclin degradation(GO:0008054)
0.0 0.1 GO:0001553 luteinization(GO:0001553)
0.0 0.1 GO:2000114 regulation of establishment of cell polarity(GO:2000114)
0.0 0.1 GO:0060390 regulation of SMAD protein import into nucleus(GO:0060390)
0.0 0.1 GO:0006477 protein sulfation(GO:0006477)
0.0 0.1 GO:0006449 regulation of translational termination(GO:0006449)
0.0 0.1 GO:0006432 phenylalanyl-tRNA aminoacylation(GO:0006432)
0.0 0.1 GO:0060433 bronchus development(GO:0060433)
0.0 0.1 GO:0060081 membrane hyperpolarization(GO:0060081)
0.0 0.1 GO:0070561 vitamin D receptor signaling pathway(GO:0070561)
0.0 0.1 GO:0043490 malate-aspartate shuttle(GO:0043490)
0.0 0.1 GO:0048625 myoblast fate commitment(GO:0048625)
0.0 0.1 GO:0007042 lysosomal lumen acidification(GO:0007042) regulation of lysosomal lumen pH(GO:0035751)
0.0 0.2 GO:0008045 motor neuron axon guidance(GO:0008045)
0.0 0.0 GO:0051834 evasion or tolerance of host defenses by virus(GO:0019049) avoidance of host defenses(GO:0044413) evasion or tolerance of host defenses(GO:0044415) avoidance of defenses of other organism involved in symbiotic interaction(GO:0051832) evasion or tolerance of defenses of other organism involved in symbiotic interaction(GO:0051834)
0.0 0.1 GO:0008049 male courtship behavior(GO:0008049)
0.0 0.1 GO:0001543 ovarian follicle rupture(GO:0001543)
0.0 0.0 GO:0046826 negative regulation of protein export from nucleus(GO:0046826)
0.0 0.1 GO:0001921 positive regulation of receptor recycling(GO:0001921)
0.0 0.1 GO:0006108 malate metabolic process(GO:0006108)
0.0 0.0 GO:0030948 negative regulation of vascular endothelial growth factor receptor signaling pathway(GO:0030948)
0.0 0.1 GO:0030091 protein repair(GO:0030091)
0.0 0.1 GO:0006105 succinate metabolic process(GO:0006105)
0.0 0.0 GO:0022038 corpus callosum development(GO:0022038)
0.0 0.0 GO:0032071 regulation of endodeoxyribonuclease activity(GO:0032071)
0.0 0.0 GO:0015864 pyrimidine nucleoside transport(GO:0015864)
0.0 0.1 GO:0051775 response to redox state(GO:0051775)
0.0 0.0 GO:0007207 phospholipase C-activating G-protein coupled acetylcholine receptor signaling pathway(GO:0007207)
0.0 0.1 GO:0010288 response to lead ion(GO:0010288)
0.0 0.0 GO:0035234 ectopic germ cell programmed cell death(GO:0035234)
0.0 0.1 GO:0022027 interkinetic nuclear migration(GO:0022027)
0.0 0.0 GO:1900116 sequestering of extracellular ligand from receptor(GO:0035581) sequestering of TGFbeta in extracellular matrix(GO:0035583) protein localization to extracellular region(GO:0071692) maintenance of protein location in extracellular region(GO:0071694) extracellular regulation of signal transduction(GO:1900115) extracellular negative regulation of signal transduction(GO:1900116)
0.0 0.0 GO:0032927 positive regulation of activin receptor signaling pathway(GO:0032927)
0.0 0.1 GO:0042492 gamma-delta T cell differentiation(GO:0042492)
0.0 0.0 GO:0006667 sphinganine metabolic process(GO:0006667)
0.0 0.0 GO:0007619 courtship behavior(GO:0007619)
0.0 0.1 GO:0018206 peptidyl-methionine modification(GO:0018206)
0.0 0.1 GO:0030644 cellular chloride ion homeostasis(GO:0030644) chloride ion homeostasis(GO:0055064)
0.0 0.1 GO:0006398 mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398)
0.0 0.0 GO:0031034 skeletal muscle myosin thick filament assembly(GO:0030241) myosin filament assembly(GO:0031034) striated muscle myosin thick filament assembly(GO:0071688)
0.0 0.1 GO:0031274 pseudopodium assembly(GO:0031269) regulation of pseudopodium assembly(GO:0031272) positive regulation of pseudopodium assembly(GO:0031274)
0.0 0.1 GO:0048013 ephrin receptor signaling pathway(GO:0048013)
0.0 0.3 GO:0000188 inactivation of MAPK activity(GO:0000188)
0.0 0.0 GO:0006562 proline catabolic process(GO:0006562)
0.0 0.0 GO:0009448 gamma-aminobutyric acid metabolic process(GO:0009448)
0.0 0.1 GO:0046952 ketone body catabolic process(GO:0046952)
0.0 0.1 GO:0048712 negative regulation of astrocyte differentiation(GO:0048712)
0.0 0.1 GO:0016246 RNA interference(GO:0016246)
0.0 0.2 GO:0000731 DNA synthesis involved in DNA repair(GO:0000731)
0.0 0.0 GO:0019805 quinolinate biosynthetic process(GO:0019805)
0.0 0.1 GO:0006591 ornithine metabolic process(GO:0006591)
0.0 0.0 GO:0030505 inorganic diphosphate transport(GO:0030505)
0.0 0.0 GO:0033262 regulation of nuclear cell cycle DNA replication(GO:0033262)
0.0 0.1 GO:1902603 carnitine shuttle(GO:0006853) carnitine transmembrane transport(GO:1902603)
0.0 0.1 GO:0006491 N-glycan processing(GO:0006491)
0.0 0.0 GO:0035511 oxidative DNA demethylation(GO:0035511)
0.0 0.0 GO:0021831 embryonic olfactory bulb interneuron precursor migration(GO:0021831)
0.0 0.1 GO:0071277 cellular response to calcium ion(GO:0071277)
0.0 0.0 GO:0046426 negative regulation of JAK-STAT cascade(GO:0046426) negative regulation of STAT cascade(GO:1904893)
0.0 0.0 GO:0035520 monoubiquitinated protein deubiquitination(GO:0035520)
0.0 0.1 GO:0060292 long term synaptic depression(GO:0060292)
0.0 0.1 GO:0071108 protein K48-linked deubiquitination(GO:0071108)
0.0 0.1 GO:0050435 beta-amyloid metabolic process(GO:0050435)
0.0 0.0 GO:0019441 tryptophan catabolic process to kynurenine(GO:0019441)
0.0 0.0 GO:0003181 atrioventricular valve development(GO:0003171) atrioventricular valve morphogenesis(GO:0003181)
0.0 0.0 GO:0032467 positive regulation of cytokinesis(GO:0032467)
0.0 0.1 GO:0006896 Golgi to endosome transport(GO:0006895) Golgi to vacuole transport(GO:0006896)
0.0 0.1 GO:0043923 positive regulation by host of viral transcription(GO:0043923)
0.0 0.0 GO:0051124 synaptic growth at neuromuscular junction(GO:0051124)
0.0 0.3 GO:0006829 zinc II ion transport(GO:0006829)
0.0 0.0 GO:0001661 conditioned taste aversion(GO:0001661)
0.0 0.0 GO:0002679 respiratory burst involved in defense response(GO:0002679)
0.0 0.0 GO:0006104 succinyl-CoA metabolic process(GO:0006104)
0.0 0.0 GO:0072385 minus-end-directed organelle transport along microtubule(GO:0072385)
0.0 0.0 GO:0002032 desensitization of G-protein coupled receptor protein signaling pathway by arrestin(GO:0002032)
0.0 0.1 GO:0034331 cell junction maintenance(GO:0034331) cell-cell junction maintenance(GO:0045217)
0.0 0.0 GO:0022030 cerebral cortex radial glia guided migration(GO:0021801) telencephalon glial cell migration(GO:0022030)
0.0 0.0 GO:0070874 negative regulation of glycogen metabolic process(GO:0070874)
0.0 0.0 GO:0051573 negative regulation of histone H3-K9 methylation(GO:0051573)
0.0 0.1 GO:0006734 NADH metabolic process(GO:0006734)
0.0 0.1 GO:0043302 positive regulation of mast cell activation involved in immune response(GO:0033008) positive regulation of leukocyte degranulation(GO:0043302) positive regulation of mast cell degranulation(GO:0043306)
0.0 0.0 GO:0006384 transcription initiation from RNA polymerase III promoter(GO:0006384)
0.0 0.1 GO:0018026 peptidyl-lysine monomethylation(GO:0018026)
0.0 0.0 GO:0070295 renal water absorption(GO:0070295)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 GO:0042765 GPI-anchor transamidase complex(GO:0042765)
0.0 0.2 GO:0005719 nuclear euchromatin(GO:0005719)
0.0 0.1 GO:0072379 BAT3 complex(GO:0071818) ER membrane insertion complex(GO:0072379)
0.0 0.2 GO:0005652 nuclear lamina(GO:0005652)
0.0 0.1 GO:0043259 laminin-10 complex(GO:0043259)
0.0 0.1 GO:0009331 glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.0 0.1 GO:0071204 histone pre-mRNA 3'end processing complex(GO:0071204)
0.0 0.1 GO:0017059 palmitoyltransferase complex(GO:0002178) serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211)
0.0 0.1 GO:0005588 collagen type V trimer(GO:0005588)
0.0 0.1 GO:0042599 lamellar body(GO:0042599)
0.0 0.0 GO:0045323 interleukin-1 receptor complex(GO:0045323)
0.0 0.0 GO:0001940 male pronucleus(GO:0001940)
0.0 0.1 GO:0031430 M band(GO:0031430)
0.0 0.0 GO:0070188 obsolete Stn1-Ten1 complex(GO:0070188)
0.0 0.1 GO:0035253 ciliary rootlet(GO:0035253)
0.0 0.1 GO:0000782 telomere cap complex(GO:0000782) nuclear telomere cap complex(GO:0000783)
0.0 0.2 GO:0071564 npBAF complex(GO:0071564)
0.0 0.0 GO:0002139 stereocilia coupling link(GO:0002139) stereocilia ankle link(GO:0002141) stereocilia ankle link complex(GO:0002142)
0.0 0.1 GO:0061202 clathrin-sculpted gamma-aminobutyric acid transport vesicle(GO:0061200) clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane(GO:0061202)
0.0 0.4 GO:0005626 obsolete insoluble fraction(GO:0005626)
0.0 0.0 GO:0000791 euchromatin(GO:0000791)
0.0 0.0 GO:0031265 CD95 death-inducing signaling complex(GO:0031265)
0.0 0.1 GO:0034451 centriolar satellite(GO:0034451)
0.0 0.1 GO:0005678 obsolete chromatin assembly complex(GO:0005678)
0.0 0.2 GO:0080008 Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.0 0.0 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
0.0 0.0 GO:0005850 eukaryotic translation initiation factor 2 complex(GO:0005850)
0.0 0.1 GO:0005675 holo TFIIH complex(GO:0005675)
0.0 0.0 GO:0071664 catenin-TCF7L2 complex(GO:0071664)
0.0 0.1 GO:0005663 DNA replication factor C complex(GO:0005663)
0.0 0.0 GO:0043625 delta DNA polymerase complex(GO:0043625)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0030297 transmembrane receptor protein tyrosine kinase activator activity(GO:0030297)
0.1 0.2 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.1 0.2 GO:0016149 translation release factor activity, codon specific(GO:0016149)
0.0 0.1 GO:0015038 glutathione disulfide oxidoreductase activity(GO:0015038)
0.0 0.1 GO:0004117 calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117)
0.0 0.1 GO:0004470 malic enzyme activity(GO:0004470)
0.0 0.2 GO:0003923 GPI-anchor transamidase activity(GO:0003923)
0.0 0.2 GO:0019211 phosphatase activator activity(GO:0019211)
0.0 0.1 GO:0004351 glutamate decarboxylase activity(GO:0004351)
0.0 0.1 GO:0033743 peptide-methionine (R)-S-oxide reductase activity(GO:0033743)
0.0 0.1 GO:0070735 protein-glycine ligase activity(GO:0070735)
0.0 0.1 GO:0003691 double-stranded telomeric DNA binding(GO:0003691)
0.0 0.1 GO:0050998 nitric-oxide synthase binding(GO:0050998)
0.0 0.1 GO:0005042 netrin receptor activity(GO:0005042)
0.0 0.1 GO:0016647 oxidoreductase activity, acting on the CH-NH group of donors, oxygen as acceptor(GO:0016647)
0.0 0.2 GO:0017169 CDP-alcohol phosphatidyltransferase activity(GO:0017169)
0.0 0.1 GO:0034187 obsolete apolipoprotein E binding(GO:0034187)
0.0 0.3 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0 0.1 GO:0098847 single-stranded telomeric DNA binding(GO:0043047) sequence-specific single stranded DNA binding(GO:0098847)
0.0 0.0 GO:0045545 syndecan binding(GO:0045545)
0.0 0.1 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.0 0.1 GO:0004367 glycerol-3-phosphate dehydrogenase [NAD+] activity(GO:0004367)
0.0 0.1 GO:0000247 C-8 sterol isomerase activity(GO:0000247)
0.0 0.1 GO:0004982 N-formyl peptide receptor activity(GO:0004982)
0.0 0.1 GO:0009374 biotin binding(GO:0009374)
0.0 0.1 GO:0042978 ornithine decarboxylase activator activity(GO:0042978)
0.0 0.2 GO:0030332 cyclin binding(GO:0030332)
0.0 0.1 GO:0017154 semaphorin receptor activity(GO:0017154)
0.0 0.1 GO:0005152 interleukin-1 receptor antagonist activity(GO:0005152)
0.0 0.1 GO:0004597 peptide-aspartate beta-dioxygenase activity(GO:0004597)
0.0 0.1 GO:0015183 L-aspartate transmembrane transporter activity(GO:0015183)
0.0 0.1 GO:0004301 epoxide hydrolase activity(GO:0004301)
0.0 0.1 GO:0016174 NAD(P)H oxidase activity(GO:0016174)
0.0 0.1 GO:0005017 platelet-derived growth factor-activated receptor activity(GO:0005017)
0.0 0.1 GO:0015016 [heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
0.0 0.0 GO:0034056 estrogen response element binding(GO:0034056)
0.0 0.1 GO:0000900 translation repressor activity, nucleic acid binding(GO:0000900)
0.0 0.1 GO:0004826 phenylalanine-tRNA ligase activity(GO:0004826)
0.0 0.0 GO:0019797 procollagen-proline 3-dioxygenase activity(GO:0019797) peptidyl-proline 3-dioxygenase activity(GO:0031544)
0.0 0.0 GO:0004477 methenyltetrahydrofolate cyclohydrolase activity(GO:0004477)
0.0 0.0 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.0 0.0 GO:0001159 RNA polymerase II core promoter proximal region sequence-specific DNA binding(GO:0000978) core promoter proximal region sequence-specific DNA binding(GO:0000987) core promoter proximal region DNA binding(GO:0001159)
0.0 0.1 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.0 0.1 GO:0008242 omega peptidase activity(GO:0008242)
0.0 0.1 GO:0070053 thrombospondin receptor activity(GO:0070053)
0.0 0.2 GO:0008353 RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.0 0.1 GO:0050780 dopamine receptor binding(GO:0050780)
0.0 0.0 GO:0016454 serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
0.0 0.1 GO:0016417 S-acyltransferase activity(GO:0016417)
0.0 0.1 GO:0016723 oxidoreductase activity, oxidizing metal ions, NAD or NADP as acceptor(GO:0016723)
0.0 0.0 GO:0003987 acetate-CoA ligase activity(GO:0003987)
0.0 0.1 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)
0.0 0.1 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.0 0.1 GO:0031685 adenosine receptor binding(GO:0031685)
0.0 0.2 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.0 0.1 GO:0015651 quaternary ammonium group transmembrane transporter activity(GO:0015651)
0.0 0.1 GO:0016361 activin receptor activity, type I(GO:0016361)
0.0 0.0 GO:0043734 DNA demethylase activity(GO:0035514) DNA-N1-methyladenine dioxygenase activity(GO:0043734)
0.0 0.0 GO:0008474 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.0 0.1 GO:0051920 peroxiredoxin activity(GO:0051920)
0.0 0.0 GO:0017060 3-galactosyl-N-acetylglucosaminide 4-alpha-L-fucosyltransferase activity(GO:0017060)
0.0 0.0 GO:0070324 thyroid hormone binding(GO:0070324)
0.0 0.0 GO:0008321 Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.0 0.0 GO:0050508 glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0050508)
0.0 0.1 GO:0050656 3'-phosphoadenosine 5'-phosphosulfate binding(GO:0050656)
0.0 0.0 GO:0004340 glucokinase activity(GO:0004340)
0.0 0.0 GO:0030235 nitric-oxide synthase regulator activity(GO:0030235)
0.0 0.0 GO:0047499 calcium-independent phospholipase A2 activity(GO:0047499)
0.0 0.1 GO:0070628 proteasome binding(GO:0070628)
0.0 0.1 GO:0046875 ephrin receptor binding(GO:0046875)
0.0 0.2 GO:0033549 MAP kinase phosphatase activity(GO:0033549)
0.0 0.1 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
0.0 0.0 GO:0043398 HLH domain binding(GO:0043398)
0.0 0.1 GO:0033170 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.0 0.1 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.0 0.1 GO:0019894 kinesin binding(GO:0019894)
0.0 0.0 GO:0015272 ATP-activated inward rectifier potassium channel activity(GO:0015272)
0.0 0.1 GO:0005536 glucose binding(GO:0005536)
0.0 0.1 GO:0016406 carnitine O-acyltransferase activity(GO:0016406)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.4 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.0 0.0 PID MET PATHWAY Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)
0.0 0.1 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.0 0.3 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.0 0.2 PID ARF6 DOWNSTREAM PATHWAY Arf6 downstream pathway
0.0 0.0 SA CASPASE CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.0 0.3 PID ALK1 PATHWAY ALK1 signaling events
0.0 0.1 PID S1P S1P4 PATHWAY S1P4 pathway
0.0 0.4 PID HNF3A PATHWAY FOXA1 transcription factor network
0.0 0.1 PID NETRIN PATHWAY Netrin-mediated signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.3 REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.0 0.3 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.0 0.2 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.0 0.3 REACTOME ENOS ACTIVATION AND REGULATION Genes involved in eNOS activation and regulation
0.0 0.2 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.0 0.2 REACTOME SIGNALING BY NOTCH4 Genes involved in Signaling by NOTCH4
0.0 0.1 REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES Genes involved in Recruitment of NuMA to mitotic centrosomes
0.0 0.3 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.0 0.1 REACTOME THROMBIN SIGNALLING THROUGH PROTEINASE ACTIVATED RECEPTORS PARS Genes involved in Thrombin signalling through proteinase activated receptors (PARs)
0.0 0.2 REACTOME DESTABILIZATION OF MRNA BY KSRP Genes involved in Destabilization of mRNA by KSRP
0.0 0.2 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
0.0 0.1 REACTOME PLATELET SENSITIZATION BY LDL Genes involved in Platelet sensitization by LDL
0.0 0.1 REACTOME ERKS ARE INACTIVATED Genes involved in ERKs are inactivated
0.0 0.1 REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX UPON TLR7 8 OR 9 STIMULATION Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation