Project
ENCODE: H3K4me1 ChIP-Seq of primary human cells
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CREMA is a free online tool that recognizes most important transcription factors that change the chromatin state across different samples.

Results for PLAG1

Z-value: 0.75

Motif logo

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Transcription factors associated with PLAG1

Gene Symbol Gene ID Gene Info
PLAG1
ENSG00000181690.3 PLAG1

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE Gene Distance Association probability Pearson corr. coef. P-value Plot
PLAG1chr8_57123092_571232566640.5658050.581.0e-01Click!
PLAG1chr8_57123328_571234844320.6806410.581.0e-01Click!
PLAG1chr8_57122281_5712243214820.3497810.561.2e-01Click!
PLAG1chr8_57121960_5712225717300.3174720.501.7e-01Click!
PLAG1chr8_57115919_5711607078440.189690-0.333.8e-01Click!

Activity of the PLAG1 motif across conditions

Conditions sorted by the z-value of the PLAG1 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE) Target Score Top associated gene Gene Info Distance of CRE to TSS CRE/Gene association probability
chr22_43523081_43523232 0.18 MCAT
 malonyl CoA:ACP acyltransferase (mitochondrial)
 15814
 0.13
chr9_37422354_37422505 0.17 GRHPR
 glyoxylate reductase/hydroxypyruvate reductase
 234
 0.93
chr11_122704075_122704226 0.17 CRTAM
 cytotoxic and regulatory T cell molecule
 5058
 0.25
chr11_71935316_71935515 0.16 INPPL1
 inositol polyphosphate phosphatase-like 1
 410
 0.73
chr19_13952219_13952496 0.16 ENSG00000207980
 .
 4884
 0.09
chr9_95727416_95727617 0.15 FGD3
 FYVE, RhoGEF and PH domain containing 3
 1273
 0.51
chr17_80507206_80507445 0.15 FOXK2
 forkhead box K2
 9891
 0.11
chr22_39678373_39678524 0.15 RP3-333H23.8
10545
 0.11
chr2_70056350_70056572 0.14 GMCL1
 germ cell-less, spermatogenesis associated 1
 313
 0.9
chr17_21188824_21188975 0.14 MAP2K3
 mitogen-activated protein kinase kinase 3
 877
 0.59
chr3_186226909_186227060 0.14 CRYGS
 crystallin, gamma S
 35256
 0.14
chr5_1098182_1098468 0.14 SLC12A7
 solute carrier family 12 (potassium/chloride transporter), member 7
 13825
 0.17
chr8_30244690_30244841 0.14 RBPMS
 RNA binding protein with multiple splicing
 41
 0.97
chr14_105541900_105542051 0.14 GPR132
 G protein-coupled receptor 132
 10193
 0.19
chr14_71109922_71110073 0.13 TTC9
 tetratricopeptide repeat domain 9
 1493
 0.43
chrX_153666124_153666275 0.13 GDI1
 GDP dissociation inhibitor 1
 933
 0.3
chr1_68299231_68299391 0.13 GNG12
 guanine nucleotide binding protein (G protein), gamma 12
 161
 0.94
chr9_100702430_100702581 0.12 HEMGN
 hemogen
 4633
 0.17
chr19_5827013_5827291 0.12 NRTN
 neurturin
 3339
 0.11
chr7_142491399_142491577 0.12 PRSS3P2
 protease, serine, 3 pseudogene 2
 10357
 0.18
chr12_49212742_49212980 0.12 CACNB3
 calcium channel, voltage-dependent, beta 3 subunit
 169
 0.9
chr3_48520196_48520441 0.12 SHISA5
 shisa family member 5
 5701
 0.1
chr3_52739214_52739466 0.12 SPCS1
 signal peptidase complex subunit 1 homolog (S. cerevisiae)
 312
 0.45
chr14_70168953_70169104 0.12 SRSF5
 serine/arginine-rich splicing factor 5
 24589
 0.21
chr16_29612175_29612326 0.12 ENSG00000266758
 .
 1664
 0.31
chr1_23811022_23811173 0.12 ASAP3
 ArfGAP with SH3 domain, ankyrin repeat and PH domain 3
 36
 0.98
chr6_42749841_42749992 0.12 GLTSCR1L
 GLTSCR1-like
 151
 0.95
chr1_45266415_45266566 0.12 PLK3
 polo-like kinase 3
 593
 0.48
chr14_68020672_68020823 0.11 TMEM229B
 transmembrane protein 229B
 20291
 0.13
chr5_169720017_169720265 0.11 LCP2
 lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa)
 5090
 0.25
chr10_73562995_73563146 0.11 CDH23
 cadherin-related 23
 7542
 0.19
chr19_5131953_5132104 0.11 CTC-482H14.5
46102
 0.14
chr10_72361747_72361953 0.11 PRF1
 perforin 1 (pore forming protein)
 665
 0.77
chr17_3807067_3807218 0.11 CAMKK1
 calcium/calmodulin-dependent protein kinase kinase 1, alpha
 10804
 0.15
chr12_89918711_89919081 0.11 POC1B
 POC1 centriolar protein B
 86
 0.71
chr4_111552676_111552827 0.11 PITX2
 paired-like homeodomain 2
 5425
 0.31
chr19_10624773_10624938 0.11 S1PR5
 sphingosine-1-phosphate receptor 5
 3248
 0.12
chr6_27798835_27799029 0.11 HIST1H4K
 histone cluster 1, H4k
 373
 0.66
chr1_54147270_54147460 0.10 ENSG00000239007
 .
 7120
 0.23
chr11_64979562_64979713 0.10 CAPN1
 calpain 1, (mu/I) large subunit
 28830
 0.08
chr6_143177440_143177974 0.10 HIVEP2
 human immunodeficiency virus type I enhancer binding protein 2
 19523
 0.26
chr3_129364392_129364543 0.10 TMCC1
 transmembrane and coiled-coil domain family 1
 11102
 0.19
chr5_142114990_142115141 0.10 ARHGAP26
 Rho GTPase activating protein 26
 34884
 0.17
chr6_157882968_157883119 0.10 ENSG00000266617
 .
 67121
 0.12
chr12_4155594_4155745 0.10 RP11-664D1.1
141283
 0.04
chr22_42721876_42722052 0.10 TCF20
 transcription factor 20 (AR1)
 17658
 0.21
chr16_75096820_75096971 0.10 ZNRF1
 zinc and ring finger 1, E3 ubiquitin protein ligase
 41787
 0.12
chr17_32582326_32582477 0.10 AC005549.3
 Uncharacterized protein
 95
 0.49
chr19_14359693_14359855 0.10 ENSG00000240803
 .
 35910
 0.12
chr17_75316372_75316547 0.10 SEPT9
 septin 9
 64
 0.98
chr11_59522047_59522436 0.10 AP000640.10
207
 0.59
chr9_124411545_124411696 0.10 DAB2IP
 DAB2 interacting protein
 2253
 0.38
chr19_10676199_10676378 0.10 KRI1
 KRI1 homolog (S. cerevisiae)
 378
 0.71
chr16_21518652_21518914 0.10 ENSG00000265462
 .
 1327
 0.39
chr11_61658320_61658531 0.09 FADS3
 fatty acid desaturase 3
 428
 0.76
chr21_36277232_36277480 0.09 RUNX1
 runt-related transcription factor 1
 15269
 0.29
chr19_14360660_14360876 0.09 ENSG00000240803
 .
 36904
 0.12
chr3_50607030_50607235 0.09 HEMK1
 HemK methyltransferase family member 1
 208
 0.89
chr2_27529413_27529622 0.09 UCN
 urocortin
 1796
 0.17
chr18_32556322_32556740 0.09 MAPRE2
 microtubule-associated protein, RP/EB family, member 2
 361
 0.92
chr7_100465661_100465812 0.09 TRIP6
 thyroid hormone receptor interactor 6
 697
 0.48
chrX_39337414_39337600 0.09 ENSG00000263730
 .
 182963
 0.03
chr17_58242675_58243016 0.09 CA4
 carbonic anhydrase IV
 7376
 0.18
chrX_48542888_48543039 0.09 WAS
 Wiskott-Aldrich syndrome
 795
 0.52
chr20_61281325_61281476 0.09 SLCO4A1
 solute carrier organic anion transporter family, member 4A1
 6311
 0.12
chr22_43524391_43524692 0.09 MCAT
 malonyl CoA:ACP acyltransferase (mitochondrial)
 14429
 0.13
chr3_4344756_4344907 0.09 SETMAR
 SET domain and mariner transposase fusion gene
 157
 0.98
chr1_160611400_160611728 0.09 SLAMF1
 signaling lymphocytic activation molecule family member 1
 5247
 0.18
chr19_13997160_13997334 0.09 C19orf57
 chromosome 19 open reading frame 57
 1946
 0.16
chr1_38591369_38591520 0.09 ENSG00000265596
 .
 36541
 0.16
chr18_2612945_2613096 0.09 NDC80
 NDC80 kinetochore complex component
 2240
 0.23
chr2_46463993_46464144 0.09 EPAS1
 endothelial PAS domain protein 1
 59679
 0.13
chr10_105725721_105725893 0.09 SLK
 STE20-like kinase
 1152
 0.46
chr8_17600949_17601376 0.09 ENSG00000212280
 .
 4465
 0.2
chr6_41373695_41373846 0.09 ENSG00000238867
 .
 50583
 0.12
chr16_21519012_21519163 0.09 ENSG00000265462
 .
 1631
 0.33
chr14_63981384_63981535 0.09 PPP2R5E
 protein phosphatase 2, regulatory subunit B', epsilon isoform
 6504
 0.16
chr4_102711634_102711787 0.09 BANK1
 B-cell scaffold protein with ankyrin repeats 1
 54
 0.99
chr5_133459140_133459291 0.09 TCF7
 transcription factor 7 (T-cell specific, HMG-box)
 94
 0.97
chr5_134182066_134182217 0.08 C5orf24
 chromosome 5 open reading frame 24
 205
 0.94
chr6_45791139_45791290 0.08 ENSG00000252738
 .
 177373
 0.03
chr14_106373318_106373469 0.08 ENSG00000211925
 .
 294
 0.49
chr5_163086384_163086535 0.08 ENSG00000251998
 .
 136712
 0.05
chr9_124459650_124459814 0.08 DAB2IP
 DAB2 interacting protein
 1917
 0.44
chr1_154694081_154694379 0.08 ADAR
 adenosine deaminase, RNA-specific
 93756
 0.05
chr17_46019203_46019438 0.08 PNPO
 pyridoxamine 5'-phosphate oxidase
 329
 0.59
chr17_25790578_25790729 0.08 RP11-720N19.2
1485
 0.42
chr10_134200331_134200482 0.08 PWWP2B
 PWWP domain containing 2B
 10266
 0.19
chr10_116252127_116252362 0.08 ABLIM1
 actin binding LIM protein 1
 4492
 0.29
chr7_70096923_70097074 0.08 AUTS2
 autism susceptibility candidate 2
 97127
 0.09
chr12_125058569_125058720 0.08 NCOR2
 nuclear receptor corepressor 2
 6634
 0.32
chr20_50010587_50010847 0.08 ENSG00000263645
 .
 16859
 0.25
chr1_3817601_3817820 0.08 C1orf174
 chromosome 1 open reading frame 174
 861
 0.57
chr22_37403941_37404092 0.08 TEX33
 testis expressed 33
 134
 0.92
chr20_247548_247703 0.08 DEFB132
 defensin, beta 132
 9248
 0.13
chr7_155259269_155259467 0.08 EN2
 engrailed homeobox 2
 8544
 0.2
chr10_73418729_73418880 0.08 CDH23
 cadherin-related 23
 13131
 0.24
chr5_81519732_81520078 0.08 RPS23
 ribosomal protein S23
 54255
 0.14
chr17_55515350_55515549 0.08 ENSG00000263902
 .
 25887
 0.22
chr22_17700910_17701256 0.08 CECR1
 cat eye syndrome chromosome region, candidate 1
 758
 0.68
chr10_115004477_115004628 0.08 TCF7L2
 transcription factor 7-like 2 (T-cell specific, HMG-box)
 93710
 0.08
chr14_105394233_105394384 0.08 PLD4
 phospholipase D family, member 4
 3092
 0.22
chrX_69654554_69654796 0.08 DLG3
 discs, large homolog 3 (Drosophila)
 10036
 0.14
chr1_33547084_33547299 0.08 ADC
 arginine decarboxylase
 423
 0.85
chr1_2360923_2361074 0.08 PLCH2
 phospholipase C, eta 2
 3579
 0.14
chr11_74699345_74699522 0.08 NEU3
 sialidase 3 (membrane sialidase)
 109
 0.96
chr19_48896794_48896968 0.08 GRIN2D
 glutamate receptor, ionotropic, N-methyl D-aspartate 2D
 1251
 0.28
chr16_881493_881644 0.08 PRR25
 proline rich 25
 26125
 0.08
chr3_37778398_37778549 0.08 ENSG00000235257
 .
 17015
 0.22
chr16_67693468_67693710 0.08 ACD
 adrenocortical dysplasia homolog (mouse)
 263
 0.79
chr3_184538634_184538824 0.08 VPS8
 vacuolar protein sorting 8 homolog (S. cerevisiae)
 3604
 0.34
chr17_1510219_1510429 0.08 SLC43A2
 solute carrier family 43 (amino acid system L transporter), member 2
 1945
 0.19
chr10_105303009_105303280 0.08 RP11-416N2.3
5688
 0.15
chr22_50047649_50047875 0.08 C22orf34
 chromosome 22 open reading frame 34
 3316
 0.26
chr9_137533190_137533341 0.08 COL5A1
 collagen, type V, alpha 1
 355
 0.89
chr5_156569548_156569699 0.08 MED7
 mediator complex subunit 7
 163
 0.5
chr10_134363175_134363446 0.08 INPP5A
 inositol polyphosphate-5-phosphatase, 40kDa
 11667
 0.21
chr1_247486505_247486904 0.08 ZNF496
 zinc finger protein 496
 5843
 0.2
chr11_69457158_69457309 0.08 CCND1
 cyclin D1
 1259
 0.5
chr5_59189611_59189822 0.08 PDE4D
 phosphodiesterase 4D, cAMP-specific
 91
 0.98
chr2_85073533_85073870 0.08 TRABD2A
 TraB domain containing 2A
 34505
 0.16
chr1_227058818_227059048 0.08 PSEN2
 presenilin 2 (Alzheimer disease 4)
 32
 0.98
chr6_21846867_21847018 0.08 ENSG00000222515
 .
 238831
 0.02
chr9_139429726_139429896 0.08 RP11-413M3.4
7522
 0.1
chr1_228651640_228651791 0.08 ENSG00000266174
 .
 1940
 0.16
chr12_56599351_56599793 0.08 ENSG00000266023
 .
 10641
 0.07
chr22_51111449_51111608 0.08 SHANK3
 SH3 and multiple ankyrin repeat domains 3
 1315
 0.29
chr22_50744729_50744925 0.07 PLXNB2
 plexin B2
 1190
 0.28
chr17_74965643_74965877 0.07 ENSG00000267568
 .
 522
 0.83
chr14_78446408_78446559 0.07 ENSG00000199440
 .
 158998
 0.03
chr1_155916486_155916693 0.07 ARHGEF2
 Rho/Rac guanine nucleotide exchange factor (GEF) 2
 4950
 0.1
chr1_27835869_27836020 0.07 RP1-159A19.4
16372
 0.16
chr17_49113821_49113972 0.07 RP11-481C4.1
5989
 0.19
chr12_121018701_121018910 0.07 POP5
 processing of precursor 5, ribonuclease P/MRP subunit (S. cerevisiae)
 377
 0.8
chr2_231899173_231899324 0.07 C2orf72
 chromosome 2 open reading frame 72
 2957
 0.2
chr16_30671534_30671721 0.07 FBRS
 fibrosin
 384
 0.7
chr7_92050709_92050934 0.07 GATAD1
 GATA zinc finger domain containing 1
 25946
 0.16
chr5_138855741_138855903 0.07 AC138517.1
 Uncharacterized protein
 3714
 0.16
chr18_19746573_19746724 0.07 GATA6
 GATA binding protein 6
 2756
 0.2
chr11_69456900_69457051 0.07 CCND1
 cyclin D1
 1001
 0.59
chr3_177444762_177445056 0.07 ENSG00000200288
 .
 102712
 0.08
chr1_203595977_203596128 0.07 ATP2B4
 ATPase, Ca++ transporting, plasma membrane 4
 124
 0.97
chr10_72282732_72282883 0.07 PALD1
 phosphatase domain containing, paladin 1
 44230
 0.14
chr8_125606366_125606517 0.07 RP11-532M24.1
14569
 0.18
chr15_74919066_74919236 0.07 CLK3
 CDC-like kinase 3
 628
 0.66
chr12_45864332_45864483 0.07 ENSG00000239178
 .
 84035
 0.11
chr5_177543276_177543552 0.07 N4BP3
 NEDD4 binding protein 3
 2970
 0.23
chr6_158235888_158236108 0.07 SNX9
 sorting nexin 9
 8298
 0.2
chr11_1784523_1784678 0.07 AC068580.5
379
 0.44
chr14_91793987_91794498 0.07 ENSG00000265856
 .
 5815
 0.23
chr10_33623276_33623430 0.07 NRP1
 neuropilin 1
 43
 0.99
chr19_1751835_1752058 0.07 ONECUT3
 one cut homeobox 3
 426
 0.78
chr17_38061449_38061600 0.07 GSDMB
 gasdermin B
 12045
 0.12
chr4_77869677_77869864 0.07 SEPT11
 septin 11
 1086
 0.58
chr1_6651106_6651286 0.07 KLHL21
 kelch-like family member 21
 8680
 0.11
chr3_196668673_196668864 0.07 NCBP2
 nuclear cap binding protein subunit 2, 20kDa
 9
 0.96
chr19_3053226_3053377 0.07 AC005944.2
393
 0.77
chr1_205781474_205781664 0.07 SLC41A1
 solute carrier family 41 (magnesium transporter), member 1
 735
 0.64
chr19_42392600_42392809 0.07 ARHGEF1
 Rho guanine nucleotide exchange factor (GEF) 1
 4189
 0.13
chr21_37450060_37450211 0.07 SETD4
 SET domain containing 4
 1552
 0.24
chr19_36359879_36360032 0.07 APLP1
 amyloid beta (A4) precursor-like protein 1
 420
 0.67
chr19_10405256_10405467 0.07 ICAM5
 intercellular adhesion molecule 5, telencephalin
 3708
 0.09
chr13_25204608_25204759 0.07 ENSG00000211508
 .
 21466
 0.17
chr17_62827977_62828181 0.07 PLEKHM1P
 pleckstrin homology domain containing, family M (with RUN domain) member 1 pseudogene
 2753
 0.18
chr19_41771793_41772060 0.07 HNRNPUL1
 heterogeneous nuclear ribonucleoprotein U-like 1
 899
 0.45
chr6_14932782_14932933 0.07 ENSG00000242989
 .
 180342
 0.03
chr17_18904649_18904946 0.07 FAM83G
 family with sequence similarity 83, member G
 2692
 0.18
chr13_24553992_24554215 0.07 SPATA13
 spermatogenesis associated 13
 159
 0.96
chr17_55622821_55622972 0.07 RP11-118E18.2
21938
 0.2
chr17_79317187_79317338 0.07 TMEM105
 transmembrane protein 105
 12788
 0.13
chr1_175096086_175096237 0.07 TNN
 tenascin N
 59167
 0.11
chr1_157819053_157819204 0.07 CD5L
 CD5 molecule-like
 7540
 0.21
chr10_118501252_118501433 0.07 HSPA12A
 heat shock 70kDa protein 12A
 743
 0.71
chr14_104338342_104338493 0.07 PPP1R13B
 protein phosphatase 1, regulatory subunit 13B
 24490
 0.13
chr17_17745639_17745790 0.07 SREBF1
 sterol regulatory element binding transcription factor 1
 5389
 0.16
chr19_16185470_16185621 0.07 TPM4
 tropomyosin 4
 951
 0.54
chr1_54639789_54639940 0.07 AL357673.1
 CDNA: FLJ21031 fis, clone CAE07336; HCG1780521; Uncharacterized protein
 1867
 0.25
chrX_56259358_56259659 0.07 KLF8
 Kruppel-like factor 8
 28
 0.99
chr4_6780074_6780278 0.07 KIAA0232
 KIAA0232
 4193
 0.24
chr5_57383801_57383952 0.07 ENSG00000238899
 .
 17861
 0.29
chr3_127449142_127449293 0.07 MGLL
 monoglyceride lipase
 5983
 0.24
chr17_38803734_38803885 0.07 SMARCE1
 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 1
 84
 0.96
chr3_173115206_173115381 0.07 NLGN1
 neuroligin 1
 277
 0.96
chr5_172068946_172069114 0.07 NEURL1B
 neuralized E3 ubiquitin protein ligase 1B
 761
 0.63
chr7_1088050_1088201 0.07 GPR146
 G protein-coupled receptor 146
 3913
 0.12
chr11_67042731_67042882 0.07 ADRBK1
 adrenergic, beta, receptor kinase 1
 8854
 0.11
chr17_43488489_43488701 0.07 ARHGAP27
 Rho GTPase activating protein 27
 803
 0.5
chr17_42624333_42624518 0.07 FZD2
 frizzled family receptor 2
 10500
 0.18
chr7_76851819_76852098 0.07 FGL2
 fibrinogen-like 2
 22815
 0.19
chr2_113033294_113033445 0.07 ZC3H6
 zinc finger CCCH-type containing 6
 191
 0.94
chr19_3668661_3668812 0.07 AC004637.1
3844
 0.14
chr15_101690975_101691174 0.07 RP11-505E24.2
64803
 0.11
chr17_75423785_75423936 0.07 SEPT9
 septin 9
 822
 0.57
chr3_13838285_13838436 0.07 ENSG00000238827
 .
 58731
 0.12
chr1_33182947_33183098 0.07 RP11-114B7.6
7816
 0.14
chr1_228947374_228947525 0.07 RHOU
 ras homolog family member U
 76625
 0.07
chr11_35641674_35641858 0.07 FJX1
 four jointed box 1 (Drosophila)
 2031
 0.39
chr7_98816047_98816198 0.07 KPNA7
 karyopherin alpha 7 (importin alpha 8)
 10993
 0.22
chr15_76603338_76603489 0.07 ETFA
 electron-transfer-flavoprotein, alpha polypeptide
 324
 0.9
chr2_44936293_44936444 0.07 ENSG00000252896
 .
 72901
 0.13

Histogram of CRE-TSS distances for CREs targeted by :

Histogram of

Rank distribution of CRE target scores:

Histogram of target CRE score.

Distribution of target CREs across different genomic regions:

Weighted Piechart of Weighted Piechart of Weighted Piechart of

Network of associatons between targets according to the STRING database.

StringDB image

First level regulatory network of PLAG1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0016080 synaptic vesicle targeting(GO:0016080)
0.0 0.1 GO:0006154 adenosine catabolic process(GO:0006154)
0.0 0.1 GO:0071364 cellular response to epidermal growth factor stimulus(GO:0071364)
0.0 0.1 GO:0001757 somite specification(GO:0001757)
0.0 0.1 GO:0010642 negative regulation of platelet-derived growth factor receptor signaling pathway(GO:0010642)
0.0 0.2 GO:0046487 glyoxylate metabolic process(GO:0046487)
0.0 0.1 GO:0045002 DNA double-strand break processing involved in repair via single-strand annealing(GO:0010792) double-strand break repair via single-strand annealing(GO:0045002)
0.0 0.1 GO:0030223 neutrophil differentiation(GO:0030223)
0.0 0.1 GO:0032650 regulation of interleukin-1 alpha production(GO:0032650) positive regulation of interleukin-1 alpha production(GO:0032730)
0.0 0.2 GO:0060391 positive regulation of SMAD protein import into nucleus(GO:0060391)
0.0 0.1 GO:0045112 integrin biosynthetic process(GO:0045112)
0.0 0.1 GO:0006337 nucleosome disassembly(GO:0006337) chromatin disassembly(GO:0031498) protein-DNA complex disassembly(GO:0032986)
0.0 0.1 GO:0007352 zygotic specification of dorsal/ventral axis(GO:0007352)
0.0 0.0 GO:0051712 positive regulation of killing of cells of other organism(GO:0051712)
0.0 0.1 GO:0050862 positive regulation of T cell receptor signaling pathway(GO:0050862)
0.0 0.1 GO:0006689 ganglioside catabolic process(GO:0006689)
0.0 0.1 GO:1903077 negative regulation of establishment of protein localization to plasma membrane(GO:0090005) negative regulation of protein localization to plasma membrane(GO:1903077) negative regulation of protein localization to cell periphery(GO:1904376)
0.0 0.1 GO:0002019 regulation of renal output by angiotensin(GO:0002019)
0.0 0.1 GO:0031061 negative regulation of histone methylation(GO:0031061)
0.0 0.1 GO:0050435 beta-amyloid metabolic process(GO:0050435)
0.0 0.1 GO:0060235 lens induction in camera-type eye(GO:0060235)
0.0 0.1 GO:0006591 ornithine metabolic process(GO:0006591)
0.0 0.1 GO:0046831 regulation of RNA export from nucleus(GO:0046831)
0.0 0.0 GO:0015015 heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.0 0.0 GO:0097576 vacuole fusion(GO:0097576)
0.0 0.0 GO:0060061 Spemann organizer formation(GO:0060061)
0.0 0.1 GO:0002418 immune response to tumor cell(GO:0002418)
0.0 0.0 GO:0032509 endosome transport via multivesicular body sorting pathway(GO:0032509)
0.0 0.1 GO:0043457 regulation of cellular respiration(GO:0043457)
0.0 0.0 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.0 0.0 GO:0008615 pyridoxine metabolic process(GO:0008614) pyridoxine biosynthetic process(GO:0008615) vitamin B6 metabolic process(GO:0042816) vitamin B6 biosynthetic process(GO:0042819)
0.0 0.0 GO:0030948 negative regulation of vascular endothelial growth factor receptor signaling pathway(GO:0030948)
0.0 0.0 GO:0035581 sequestering of extracellular ligand from receptor(GO:0035581) sequestering of TGFbeta in extracellular matrix(GO:0035583) protein localization to extracellular region(GO:0071692) maintenance of protein location in extracellular region(GO:0071694) extracellular regulation of signal transduction(GO:1900115) extracellular negative regulation of signal transduction(GO:1900116)
0.0 0.0 GO:0021819 layer formation in cerebral cortex(GO:0021819)
0.0 0.1 GO:0032020 ISG15-protein conjugation(GO:0032020)
0.0 0.1 GO:0051798 positive regulation of hair cycle(GO:0042635) positive regulation of hair follicle development(GO:0051798)
0.0 0.0 GO:0035405 histone-threonine phosphorylation(GO:0035405)
0.0 0.0 GO:0018119 protein nitrosylation(GO:0017014) peptidyl-cysteine S-nitrosylation(GO:0018119)
0.0 0.1 GO:0032464 positive regulation of protein homooligomerization(GO:0032464)
0.0 0.0 GO:1901419 regulation of response to alcohol(GO:1901419)
0.0 0.1 GO:0016553 base conversion or substitution editing(GO:0016553)
0.0 0.0 GO:0002328 pro-B cell differentiation(GO:0002328)
0.0 0.0 GO:1903170 negative regulation of release of sequestered calcium ion into cytosol(GO:0051280) positive regulation of sequestering of calcium ion(GO:0051284) negative regulation of calcium ion transmembrane transport(GO:1903170)
0.0 0.0 GO:0060916 mesenchymal cell proliferation involved in lung development(GO:0060916)
0.0 0.0 GO:0021978 telencephalon regionalization(GO:0021978)
0.0 0.0 GO:0046121 deoxyribonucleoside catabolic process(GO:0046121)
0.0 0.1 GO:0033197 response to vitamin E(GO:0033197)
0.0 0.1 GO:0015074 DNA integration(GO:0015074)
0.0 0.0 GO:0043247 protection from non-homologous end joining at telomere(GO:0031848) telomere maintenance in response to DNA damage(GO:0043247)
0.0 0.1 GO:0071354 cellular response to interleukin-6(GO:0071354)
0.0 0.1 GO:0019987 obsolete negative regulation of anti-apoptosis(GO:0019987)
0.0 0.0 GO:0006922 obsolete cleavage of lamin involved in execution phase of apoptosis(GO:0006922)
0.0 0.1 GO:0042487 regulation of odontogenesis of dentin-containing tooth(GO:0042487)
0.0 0.0 GO:0010803 regulation of tumor necrosis factor-mediated signaling pathway(GO:0010803)
0.0 0.1 GO:0021683 cerebellar granular layer development(GO:0021681) cerebellar granular layer morphogenesis(GO:0021683) cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707)
0.0 0.0 GO:0060363 cranial suture morphogenesis(GO:0060363) craniofacial suture morphogenesis(GO:0097094)
0.0 0.0 GO:0006089 lactate metabolic process(GO:0006089)
0.0 0.1 GO:0050957 equilibrioception(GO:0050957)
0.0 0.0 GO:0090286 cytoskeletal anchoring at nuclear membrane(GO:0090286)
0.0 0.0 GO:0098870 neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0031904 endosome lumen(GO:0031904)
0.0 0.1 GO:0005588 collagen type V trimer(GO:0005588)
0.0 0.1 GO:0030895 apolipoprotein B mRNA editing enzyme complex(GO:0030895)
0.0 0.1 GO:0005787 signal peptidase complex(GO:0005787)
0.0 0.1 GO:0000300 obsolete peripheral to membrane of membrane fraction(GO:0000300)
0.0 0.0 GO:0070044 synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044)
0.0 0.1 GO:0044224 juxtaparanode region of axon(GO:0044224)
0.0 0.1 GO:0005766 primary lysosome(GO:0005766) azurophil granule(GO:0042582)
0.0 0.0 GO:0034992 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0004803 transposase activity(GO:0004803)
0.0 0.1 GO:0004476 mannose-6-phosphate isomerase activity(GO:0004476)
0.0 0.1 GO:0004308 exo-alpha-sialidase activity(GO:0004308) alpha-sialidase activity(GO:0016997)
0.0 0.2 GO:0046030 inositol-polyphosphate 5-phosphatase activity(GO:0004445) inositol trisphosphate phosphatase activity(GO:0046030)
0.0 0.1 GO:0008821 crossover junction endodeoxyribonuclease activity(GO:0008821)
0.0 0.1 GO:0050544 arachidonic acid binding(GO:0050544)
0.0 0.1 GO:0055077 gap junction hemi-channel activity(GO:0055077)
0.0 0.1 GO:0031435 mitogen-activated protein kinase kinase kinase binding(GO:0031435)
0.0 0.1 GO:0005030 neurotrophin receptor activity(GO:0005030)
0.0 0.1 GO:0042978 ornithine decarboxylase activator activity(GO:0042978)
0.0 0.1 GO:0015226 amino-acid betaine transmembrane transporter activity(GO:0015199) carnitine transmembrane transporter activity(GO:0015226)
0.0 0.2 GO:0008143 poly(A) binding(GO:0008143)
0.0 0.1 GO:0019863 IgE binding(GO:0019863)
0.0 0.1 GO:0042043 neurexin family protein binding(GO:0042043)
0.0 0.0 GO:0003680 AT DNA binding(GO:0003680)
0.0 0.0 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 0.1 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0 0.1 GO:0031685 adenosine receptor binding(GO:0031685)
0.0 0.0 GO:0035184 histone threonine kinase activity(GO:0035184)
0.0 0.1 GO:0004305 ethanolamine kinase activity(GO:0004305)
0.0 0.1 GO:0048020 CCR chemokine receptor binding(GO:0048020)
0.0 0.1 GO:0004030 aldehyde dehydrogenase [NAD(P)+] activity(GO:0004030)
0.0 0.0 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.0 0.1 GO:0015379 potassium:chloride symporter activity(GO:0015379)
0.0 0.1 GO:0005112 Notch binding(GO:0005112)
0.0 0.1 GO:0031694 alpha-2A adrenergic receptor binding(GO:0031694)
0.0 0.0 GO:0003960 NADPH:quinone reductase activity(GO:0003960)
0.0 0.1 GO:0008273 calcium, potassium:sodium antiporter activity(GO:0008273)
0.0 0.1 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.0 0.1 GO:0070290 N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.0 0.0 GO:0032794 GTPase activating protein binding(GO:0032794)
0.0 0.0 GO:0070324 thyroid hormone binding(GO:0070324)
0.0 0.0 GO:0001849 complement component C1q binding(GO:0001849)
0.0 0.2 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.0 0.0 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.0 0.1 GO:0034452 dynactin binding(GO:0034452)
0.0 0.0 GO:0015137 citrate transmembrane transporter activity(GO:0015137) tricarboxylic acid transmembrane transporter activity(GO:0015142)
0.0 0.1 GO:0008187 poly-pyrimidine tract binding(GO:0008187)
0.0 0.1 GO:0016717 oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water(GO:0016717)
0.0 0.0 GO:0035014 phosphatidylinositol 3-kinase regulator activity(GO:0035014)
0.0 0.1 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.0 0.0 GO:0042608 T cell receptor binding(GO:0042608)
0.0 0.1 GO:0005031 tumor necrosis factor-activated receptor activity(GO:0005031)
0.0 0.0 GO:0017060 3-galactosyl-N-acetylglucosaminide 4-alpha-L-fucosyltransferase activity(GO:0017060)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.0 0.0 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.0 0.1 PID GMCSF PATHWAY GMCSF-mediated signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.0 REACTOME ADENYLATE CYCLASE INHIBITORY PATHWAY Genes involved in Adenylate cyclase inhibitory pathway
0.0 0.1 REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION Genes involved in APOBEC3G mediated resistance to HIV-1 infection