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ENCODE: H3K4me1 ChIP-Seq of primary human cells
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CREMA is a free online tool that recognizes most important transcription factors that change the chromatin state across different samples.

Results for POU2F2_POU3F1

Z-value: 0.66

Motif logo

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Transcription factors associated with POU2F2_POU3F1

Gene Symbol Gene ID Gene Info
POU2F2
ENSG00000028277.16 POU2F2
POU3F1
ENSG00000185668.5 POU3F1

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE Gene Distance Association probability Pearson corr. coef. P-value Plot
POU2F2chr19_42635993_426362634150.4961190.703.7e-02Click!
POU2F2chr19_42594081_4259427353800.1122160.665.3e-02Click!
POU2F2chr19_42596601_4259684128360.146320-0.636.7e-02Click!
POU2F2chr19_42591906_4259205775760.1044400.521.5e-01Click!
POU2F2chr19_42617143_4261729438210.121040-0.511.6e-01Click!
POU3F1chr1_38510263_3851041421120.2548700.599.4e-02Click!
POU3F1chr1_38510844_3851099515310.3321240.571.1e-01Click!
POU3F1chr1_38511967_385122673330.8570730.501.7e-01Click!
POU3F1chr1_38504476_3850462778990.146533-0.472.0e-01Click!
POU3F1chr1_38513126_385132947600.5966140.343.6e-01Click!

Activity of the POU2F2_POU3F1 motif across conditions

Conditions sorted by the z-value of the POU2F2_POU3F1 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE) Target Score Top associated gene Gene Info Distance of CRE to TSS CRE/Gene association probability
chr20_52235971_52236462 0.32 ZNF217
 zinc finger protein 217
 10785
 0.21
chr19_7740804_7740982 0.27 C19orf59
 chromosome 19 open reading frame 59
 621
 0.48
chr9_128521593_128522112 0.25 PBX3
 pre-B-cell leukemia homeobox 3
 11374
 0.27
chr1_236056970_236057121 0.25 LYST
 lysosomal trafficking regulator
 10173
 0.17
chr1_27124754_27124905 0.25 PIGV
 phosphatidylinositol glycan anchor biosynthesis, class V
 9410
 0.12
chr3_59739840_59740076 0.24 NPCDR1
 nasopharyngeal carcinoma, down-regulated 1
 217625
 0.02
chr20_8133032_8133204 0.21 PLCB1
 phospholipase C, beta 1 (phosphoinositide-specific)
 19816
 0.25
chr11_33888634_33888798 0.21 LMO2
 LIM domain only 2 (rhombotin-like 1)
 2646
 0.28
chr17_8857372_8857659 0.21 PIK3R5
 phosphoinositide-3-kinase, regulatory subunit 5
 11509
 0.24
chr2_12576010_12576233 0.20 ENSG00000207183
 .
 24494
 0.27
chr11_121318869_121319068 0.19 SORL1
 sortilin-related receptor, L(DLR class) A repeats containing
 3944
 0.27
chrX_9389105_9389322 0.19 TBL1X
 transducin (beta)-like 1X-linked
 42122
 0.21
chr1_150972687_150972863 0.19 FAM63A
 family with sequence similarity 63, member A
 2129
 0.15
chr11_128298881_128299249 0.19 ETS1
 v-ets avian erythroblastosis virus E26 oncogene homolog 1
 76224
 0.11
chr11_74177636_74177787 0.18 KCNE3
 potassium voltage-gated channel, Isk-related family, member 3
 883
 0.49
chr19_7071064_7071215 0.17 ZNF557
 zinc finger protein 557
 1423
 0.31
chr8_89012070_89012346 0.17 CTB-118P15.2
25815
 0.26
chr2_148056613_148056764 0.17 ENSG00000238860
 .
 24851
 0.25
chr17_75865999_75866188 0.17 FLJ45079
12566
 0.24
chr19_44124055_44124283 0.17 ZNF428
 zinc finger protein 428
 143
 0.9
chrX_131116484_131116635 0.16 ENSG00000265686
 .
 14314
 0.21
chr2_68917459_68917725 0.16 ARHGAP25
 Rho GTPase activating protein 25
 20042
 0.22
chr2_65658480_65658678 0.16 SPRED2
 sprouty-related, EVH1 domain containing 2
 732
 0.75
chr14_107170404_107170573 0.16 IGHV1-69
 immunoglobulin heavy variable 1-69
 60
 0.89
chr1_115650011_115650162 0.16 TSPAN2
 tetraspanin 2
 17965
 0.25
chr18_45497773_45497992 0.16 SMAD2
 SMAD family member 2
 40367
 0.18
chr3_105492667_105492818 0.16 CBLB
 Cbl proto-oncogene B, E3 ubiquitin protein ligase
 71697
 0.14
chr7_75370305_75370568 0.16 HIP1
 huntingtin interacting protein 1
 2171
 0.32
chr18_74142915_74143066 0.15 ZNF516
 zinc finger protein 516
 52122
 0.12
chr7_115665073_115665289 0.15 TFEC
 transcription factor EC
 5614
 0.33
chr15_65596753_65596904 0.15 ENSG00000200156
 .
 187
 0.92
chr2_145237384_145237678 0.15 ZEB2
 zinc finger E-box binding homeobox 2
 37584
 0.19
chr20_1682917_1683078 0.15 ENSG00000242348
 .
 35991
 0.14
chr9_125110159_125110401 0.15 PTGS1
 prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
 22544
 0.11
chr9_93581189_93581340 0.15 SYK
 spleen tyrosine kinase
 8506
 0.33
chr10_11221294_11221576 0.15 RP3-323N1.2
8096
 0.22
chr17_64786718_64786990 0.15 ENSG00000207943
 .
 3664
 0.27
chr7_30252775_30252926 0.15 AC007036.5
55703
 0.1
chr21_16400437_16400588 0.15 NRIP1
 nuclear receptor interacting protein 1
 25823
 0.21
chr6_108437868_108438019 0.15 OSTM1
 osteopetrosis associated transmembrane protein 1
 42002
 0.13
chr3_11405171_11405322 0.14 ATG7
 autophagy related 7
 885
 0.73
chr1_88927950_88928373 0.14 ENSG00000239504
 .
 15636
 0.29
chr8_145033195_145033467 0.14 PLEC
 plectin
 364
 0.77
chr11_44647324_44647548 0.14 CD82
 CD82 molecule
 7616
 0.2
chr10_123702458_123702803 0.14 ATE1
 arginyltransferase 1
 14314
 0.17
chr15_100050595_100050746 0.14 AC015660.1
 HCG1993240; Serologically defined breast cancer antigen NY-BR-40; Uncharacterized protein
 12092
 0.22
chr18_32738642_32739146 0.14 ZNF397
 zinc finger protein 397
 82106
 0.09
chr14_89890480_89890631 0.14 FOXN3-AS1
 FOXN3 antisense RNA 1
 6857
 0.18
chr16_87098812_87099097 0.14 RP11-899L11.3
150567
 0.04
chr14_62021015_62021340 0.14 RP11-47I22.1
9172
 0.19
chr11_34466397_34466650 0.14 CAT
 catalase
 6051
 0.24
chr18_74728060_74728211 0.13 MBP
 myelin basic protein
 863
 0.7
chr20_49073611_49073762 0.13 ENSG00000244376
 .
 27666
 0.17
chr11_121300720_121300871 0.13 SORL1
 sortilin-related receptor, L(DLR class) A repeats containing
 22117
 0.22
chr17_71663578_71663963 0.13 SDK2
 sidekick cell adhesion molecule 2
 23542
 0.21
chr12_42491533_42491785 0.13 ENSG00000222884
 .
 18096
 0.22
chr17_34618701_34619108 0.13 CCL3L1
 chemokine (C-C motif) ligand 3-like 1
 6815
 0.15
chr6_10415477_10415681 0.13 TFAP2A
 transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
 98
 0.92
chr8_38238060_38238354 0.13 WHSC1L1
 Wolf-Hirschhorn syndrome candidate 1-like 1
 132
 0.94
chr1_206853825_206853976 0.13 ENSG00000252853
 .
 1408
 0.34
chr9_95680131_95680423 0.13 FGD3
 FYVE, RhoGEF and PH domain containing 3
 29456
 0.15
chr7_148543974_148544125 0.13 ENSG00000251712
 .
 25945
 0.15
chr8_117098467_117098665 0.13 ENSG00000221793
 .
 50432
 0.17
chr12_126892098_126892249 0.13 ENSG00000239776
 .
 758499
 0.0
chr1_85034082_85034233 0.13 CTBS
 chitobiase, di-N-acetyl-
 5990
 0.22
chr6_74596622_74597048 0.13 RP11-553A21.3
190981
 0.03
chrX_39967009_39967167 0.13 BCOR
 BCL6 corepressor
 10432
 0.31
chr6_134952900_134953159 0.13 ALDH8A1
 aldehyde dehydrogenase 8 family, member A1
 297270
 0.01
chr15_78330161_78330463 0.13 ENSG00000221476
 .
 561
 0.69
chr8_42570638_42570789 0.13 RP11-412B14.1
6376
 0.2
chr3_174158369_174158546 0.13 NAALADL2
 N-acetylated alpha-linked acidic dipeptidase-like 2
 320
 0.95
chr14_65653400_65653551 0.13 ENSG00000222985
 .
 62215
 0.11
chr14_97879593_97879822 0.12 ENSG00000240730
 .
 116803
 0.07
chr6_167459920_167460071 0.12 FGFR1OP
 FGFR1 oncogene partner
 47099
 0.1
chr2_143901991_143902142 0.12 ARHGAP15
 Rho GTPase activating protein 15
 15183
 0.24
chr8_42358689_42358903 0.12 SLC20A2
 solute carrier family 20 (phosphate transporter), member 2
 35
 0.98
chr12_11898782_11898933 0.12 ETV6
 ets variant 6
 6578
 0.31
chr14_89824555_89824893 0.12 RP11-356K23.2
3320
 0.22
chr21_36880587_36880797 0.12 ENSG00000211590
 .
 212321
 0.02
chr17_75537165_75537316 0.12 SEPT9
 septin 9
 59245
 0.11
chr2_111460570_111460721 0.12 BUB1
 BUB1 mitotic checkpoint serine/threonine kinase
 24954
 0.19
chr2_153577209_153577360 0.12 PRPF40A
 PRP40 pre-mRNA processing factor 40 homolog A (S. cerevisiae)
 2789
 0.29
chr19_45979428_45979579 0.12 ERCC1
 excision repair cross-complementing rodent repair deficiency, complementation group 1 (includes overlapping antisense sequence)
 2583
 0.16
chr13_102358599_102359128 0.12 ENSG00000201155
 .
 72535
 0.12
chr16_31203148_31203299 0.12 RP11-388M20.1
4229
 0.08
chr13_77298499_77298913 0.12 KCTD12
 potassium channel tetramerization domain containing 12
 161819
 0.04
chr21_42740444_42740595 0.12 MX2
 myxovirus (influenza virus) resistance 2 (mouse)
 1493
 0.43
chr9_80638232_80638563 0.12 GNAQ
 guanine nucleotide binding protein (G protein), q polypeptide
 7123
 0.32
chr16_50188525_50189647 0.12 PAPD5
 PAP associated domain containing 5
 1307
 0.38
chr5_87851464_87851615 0.12 ENSG00000245526
 .
 111218
 0.06
chr13_73614878_73615077 0.12 KLF5
 Kruppel-like factor 5 (intestinal)
 14137
 0.24
chr3_185313043_185313423 0.12 SENP2
 SUMO1/sentrin/SMT3 specific peptidase 2
 9150
 0.23
chr7_92268630_92268956 0.12 FAM133B
 family with sequence similarity 133, member B
 49085
 0.13
chr12_100379154_100379362 0.12 ANKS1B
 ankyrin repeat and sterile alpha motif domain containing 1B
 826
 0.71
chr15_70924626_70924810 0.12 UACA
 uveal autoantigen with coiled-coil domains and ankyrin repeats
 69902
 0.13
chr15_58962808_58962959 0.12 ENSG00000199730
 .
 33470
 0.15
chrX_71301884_71302112 0.12 RGAG4
 retrotransposon gag domain containing 4
 49680
 0.11
chr14_75342747_75342964 0.12 DLST
 dihydrolipoamide S-succinyltransferase (E2 component of 2-oxo-glutarate complex)
 5741
 0.15
chr4_37929159_37929310 0.12 PTTG2
 pituitary tumor-transforming 2
 32822
 0.19
chr18_42301796_42301947 0.12 SETBP1
 SET binding protein 1
 24742
 0.28
chrX_20257547_20257698 0.12 RPS6KA3
 ribosomal protein S6 kinase, 90kDa, polypeptide 3
 2184
 0.38
chr12_47604728_47604942 0.12 PCED1B
 PC-esterase domain containing 1B
 5217
 0.24
chr1_180238794_180238945 0.12 RP5-1180C10.2
4947
 0.26
chr4_74570587_74570738 0.12 IL8
 interleukin 8
 35561
 0.18
chr7_40319999_40320150 0.12 SUGCT
 succinylCoA:glutarate-CoA transferase
 145455
 0.04
chr6_163858584_163858820 0.12 QKI
 QKI, KH domain containing, RNA binding
 14462
 0.31
chr2_182176568_182176883 0.12 ENSG00000266705
 .
 6346
 0.33
chr18_60805998_60806472 0.11 RP11-299P2.1
12318
 0.25
chr18_77443310_77443575 0.11 CTDP1
 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1
 2593
 0.34
chr14_53151982_53152133 0.11 ERO1L
 ERO1-like (S. cerevisiae)
 10190
 0.17
chr7_149484946_149485199 0.11 ZNF467
 zinc finger protein 467
 14504
 0.19
chr7_132145909_132146078 0.11 AC011625.1
108900
 0.07
chr8_92043874_92044025 0.11 TMEM55A
 transmembrane protein 55A
 9114
 0.13
chr2_8675916_8676101 0.11 AC011747.7
139888
 0.05
chr1_224517230_224517440 0.11 NVL
 nuclear VCP-like
 488
 0.74
chr19_14484274_14484425 0.11 CD97
 CD97 molecule
 7619
 0.15
chr20_55949324_55949933 0.11 MTRNR2L3
 MT-RNR2-like 3
 14750
 0.12
chr7_105672052_105672243 0.11 CDHR3
 cadherin-related family member 3
 16577
 0.25
chrX_66942601_66942860 0.11 AR
 androgen receptor
 153999
 0.04
chr3_30772744_30772895 0.11 RP11-1024P17.1
33666
 0.23
chr12_54329115_54329387 0.11 HOXC13
 homeobox C13
 3284
 0.11
chrX_67904761_67904916 0.11 STARD8
 StAR-related lipid transfer (START) domain containing 8
 8655
 0.3
chrX_4465282_4465433 0.11 ENSG00000264861
 .
 36184
 0.24
chr14_51279547_51280135 0.11 RP11-286O18.1
8757
 0.15
chrX_41564421_41564572 0.11 GPR34
 G protein-coupled receptor 34
 16237
 0.17
chr7_127643499_127643771 0.11 LRRC4
 leucine rich repeat containing 4
 27423
 0.21
chr9_127133050_127133201 0.11 ENSG00000264237
 .
 20315
 0.18
chr6_158432783_158432992 0.11 SYNJ2
 synaptojanin 2
 5610
 0.21
chr4_184826745_184826896 0.11 STOX2
 storkhead box 2
 311
 0.93
chr17_72674371_72674771 0.11 CTD-2006K23.2
832
 0.49
chr2_20640112_20640280 0.11 RHOB
 ras homolog family member B
 6639
 0.2
chr3_171677744_171677895 0.11 TMEM212-IT1
 TMEM212 intronic transcript 1 (non-protein coding)
 65593
 0.12
chr15_59016430_59016630 0.11 ENSG00000199730
 .
 20177
 0.14
chr10_80009477_80009629 0.11 ENSG00000201393
 .
 117711
 0.06
chr17_58602448_58602716 0.11 APPBP2
 amyloid beta precursor protein (cytoplasmic tail) binding protein 2
 902
 0.42
chr3_153345776_153346013 0.11 ENSG00000200162
 .
 20728
 0.26
chr1_95067399_95068170 0.11 F3
 coagulation factor III (thromboplastin, tissue factor)
 60428
 0.14
chr1_90171872_90172143 0.11 ENSG00000239176
 .
 61870
 0.1
chr1_8557969_8558120 0.11 ENSG00000221083
 .
 13934
 0.21
chr9_130218314_130218465 0.11 LRSAM1
 leucine rich repeat and sterile alpha motif containing 1
 3855
 0.15
chr12_107423478_107423629 0.11 CRY1
 cryptochrome 1 (photolyase-like)
 32236
 0.15
chr17_79420315_79420555 0.11 ENSG00000266189
 .
 2221
 0.18
chr11_7517583_7517734 0.11 OLFML1
 olfactomedin-like 1
 10821
 0.17
chr4_164465378_164465701 0.11 ENSG00000264535
 .
 21095
 0.2
chr14_23292384_23292986 0.11 SLC7A7
 solute carrier family 7 (amino acid transporter light chain, y+L system), member 7
 65
 0.91
chr20_5259915_5260066 0.11 PROKR2
 prokineticin receptor 2
 35025
 0.17
chr1_16182379_16182530 0.11 RP11-169K16.9
7812
 0.15
chr4_37750487_37750638 0.11 ENSG00000207075
 .
 48938
 0.14
chr2_170447183_170447355 0.11 PPIG
 peptidylprolyl isomerase G (cyclophilin G)
 6112
 0.19
chr6_138820271_138821054 0.11 NHSL1
 NHS-like 1
 31
 0.98
chr8_87538067_87538218 0.11 CPNE3
 copine III
 3149
 0.26
chr8_59234754_59234905 0.11 UBXN2B
 UBX domain protein 2B
 88994
 0.1
chr5_118685150_118685301 0.11 TNFAIP8
 tumor necrosis factor, alpha-induced protein 8
 4784
 0.24
chr3_23918662_23918822 0.10 RPL15
 ribosomal protein L15
 39294
 0.13
chr7_138729483_138729741 0.10 ZC3HAV1L
 zinc finger CCCH-type, antiviral 1-like
 8837
 0.21
chr9_134576003_134576154 0.10 RAPGEF1
 Rap guanine nucleotide exchange factor (GEF) 1
 9151
 0.22
chr8_142283208_142283359 0.10 RP11-10J21.3
 Uncharacterized protein
 18619
 0.13
chr2_20795415_20795848 0.10 HS1BP3-IT1
 HS1BP3 intronic transcript 1 (non-protein coding)
 3323
 0.28
chr1_156715184_156715335 0.10 MRPL24
 mitochondrial ribosomal protein L24
 3877
 0.11
chr2_89196646_89196797 0.10 IGKV5-2
 immunoglobulin kappa variable 5-2
 27
 0.94
chr4_85675065_85675338 0.10 WDFY3
 WD repeat and FYVE domain containing 3
 20586
 0.22
chr19_12251766_12251987 0.10 ZNF20
 zinc finger protein 20
 654
 0.56
chr9_2779950_2780101 0.10 KCNV2
 potassium channel, subfamily V, member 2
 62523
 0.12
chr5_58324099_58324383 0.10 PDE4D
 phosphodiesterase 4D, cAMP-specific
 11098
 0.24
chr1_42194590_42194741 0.10 HIVEP3
 human immunodeficiency virus type I enhancer binding protein 3
 27993
 0.2
chr1_233249399_233249689 0.10 PCNXL2
 pecanex-like 2 (Drosophila)
 46509
 0.19
chr2_128121786_128121937 0.10 MAP3K2
 mitogen-activated protein kinase kinase kinase 2
 21056
 0.15
chr1_211780228_211780379 0.10 RP11-359E8.5
23236
 0.15
chr12_32914885_32915254 0.10 YARS2
 tyrosyl-tRNA synthetase 2, mitochondrial
 6233
 0.27
chr8_131334569_131334937 0.10 ASAP1
 ArfGAP with SH3 domain, ankyrin repeat and PH domain 1
 18430
 0.28
chr2_157185455_157185656 0.10 NR4A2
 nuclear receptor subfamily 4, group A, member 2
 1078
 0.63
chr8_10057114_10057265 0.10 MSRA
 methionine sulfoxide reductase A
 101856
 0.07
chr20_30664906_30665122 0.10 HCK
 hemopoietic cell kinase
 24950
 0.11
chr8_126364779_126364994 0.10 RP11-550A5.2
1228
 0.57
chr1_28216990_28217238 0.10 RPA2
 replication protein A2, 32kDa
 6482
 0.12
chr14_92929645_92929817 0.10 SLC24A4
 solute carrier family 24 (sodium/potassium/calcium exchanger), member 4
 24023
 0.22
chr2_585352_585503 0.10 TMEM18
 transmembrane protein 18
 90348
 0.08
chr6_118640738_118640889 0.10 PLN
 phospholamban
 228648
 0.02
chr4_71997230_71997381 0.10 SLC4A4
 solute carrier family 4 (sodium bicarbonate cotransporter), member 4
 55698
 0.16
chr8_101167520_101167671 0.10 SPAG1
 sperm associated antigen 1
 2539
 0.18
chr10_124759303_124759454 0.10 IKZF5
 IKAROS family zinc finger 5 (Pegasus)
 8955
 0.16
chr18_13449905_13450056 0.10 ENSG00000266146
 .
 9966
 0.11
chr14_75590857_75591241 0.10 NEK9
 NIMA-related kinase 9
 2694
 0.19
chr11_14916609_14916856 0.10 CYP2R1
 cytochrome P450, family 2, subfamily R, polypeptide 1
 2934
 0.3
chr2_16820769_16820938 0.10 FAM49A
 family with sequence similarity 49, member A
 16509
 0.29
chr20_47346681_47346832 0.10 ENSG00000251876
 .
 9229
 0.29
chr21_25351038_25351189 0.10 ENSG00000199698
 .
 546511
 0.0
chr2_190438141_190438314 0.10 SLC40A1
 solute carrier family 40 (iron-regulated transporter), member 1
 7386
 0.25
chr15_85545977_85546158 0.10 PDE8A
 phosphodiesterase 8A
 20855
 0.18
chr14_91114335_91114715 0.10 TTC7B
 tetratricopeptide repeat domain 7B
 3973
 0.2
chrX_44171967_44172138 0.10 EFHC2
 EF-hand domain (C-terminal) containing 2
 30866
 0.23
chr7_152039023_152039174 0.10 ENSG00000253088
 .
 60767
 0.12
chrX_37635424_37635599 0.10 CYBB
 cytochrome b-245, beta polypeptide
 3753
 0.3
chr11_123446813_123446964 0.10 GRAMD1B
 GRAM domain containing 1B
 15903
 0.22
chr3_5022118_5022424 0.10 BHLHE40-AS1
 BHLHE40 antisense RNA 1
 625
 0.66
chr1_84903246_84903518 0.10 DNASE2B
 deoxyribonuclease II beta
 29469
 0.16
chrX_78407484_78407783 0.10 GPR174
 G protein-coupled receptor 174
 18836
 0.29
chr7_37826197_37826598 0.10 GPR141
 G protein-coupled receptor 141
 46401
 0.16
chr22_24524083_24524234 0.10 KB-318B8.7
26506
 0.14
chr17_5133380_5133531 0.10 SCIMP
 SLP adaptor and CSK interacting membrane protein
 4663
 0.16

Histogram of CRE-TSS distances for CREs targeted by :

Histogram of

Rank distribution of CRE target scores:

Histogram of target CRE score.

Distribution of target CREs across different genomic regions:

Weighted Piechart of Weighted Piechart of Weighted Piechart of

Network of associatons between targets according to the STRING database.

StringDB image

First level regulatory network of POU2F2_POU3F1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0032632 interleukin-3 production(GO:0032632)
0.0 0.1 GO:0070172 positive regulation of tooth mineralization(GO:0070172)
0.0 0.1 GO:0031061 negative regulation of histone methylation(GO:0031061)
0.0 0.1 GO:0033169 histone H3-K9 demethylation(GO:0033169)
0.0 0.1 GO:0006210 pyrimidine nucleobase catabolic process(GO:0006208) thymine catabolic process(GO:0006210) thymine metabolic process(GO:0019859)
0.0 0.1 GO:0070672 response to interleukin-15(GO:0070672)
0.0 0.1 GO:0032641 lymphotoxin A production(GO:0032641) lymphotoxin A biosynthetic process(GO:0042109)
0.0 0.2 GO:0044341 sodium-dependent phosphate transport(GO:0044341)
0.0 0.0 GO:0034720 histone H3-K4 demethylation(GO:0034720)
0.0 0.1 GO:0002430 complement receptor mediated signaling pathway(GO:0002430)
0.0 0.1 GO:0032237 activation of store-operated calcium channel activity(GO:0032237) regulation of store-operated calcium channel activity(GO:1901339) positive regulation of store-operated calcium channel activity(GO:1901341)
0.0 0.1 GO:0019441 tryptophan catabolic process to kynurenine(GO:0019441)
0.0 0.1 GO:0050858 negative regulation of antigen receptor-mediated signaling pathway(GO:0050858) negative regulation of T cell receptor signaling pathway(GO:0050860)
0.0 0.0 GO:0043320 natural killer cell activation involved in immune response(GO:0002323) natural killer cell degranulation(GO:0043320)
0.0 0.1 GO:0045647 negative regulation of erythrocyte differentiation(GO:0045647)
0.0 0.0 GO:0002606 positive regulation of dendritic cell antigen processing and presentation(GO:0002606)
0.0 0.1 GO:0015671 oxygen transport(GO:0015671)
0.0 0.1 GO:0042416 dopamine biosynthetic process(GO:0042416)
0.0 0.0 GO:0032509 endosome transport via multivesicular body sorting pathway(GO:0032509)
0.0 0.1 GO:0010988 regulation of low-density lipoprotein particle clearance(GO:0010988)
0.0 0.1 GO:0002634 regulation of germinal center formation(GO:0002634)
0.0 0.0 GO:0033148 positive regulation of intracellular estrogen receptor signaling pathway(GO:0033148)
0.0 0.0 GO:0035405 histone-threonine phosphorylation(GO:0035405)
0.0 0.0 GO:0009786 regulation of asymmetric cell division(GO:0009786)
0.0 0.1 GO:0006663 platelet activating factor biosynthetic process(GO:0006663)
0.0 0.0 GO:0006420 arginyl-tRNA aminoacylation(GO:0006420)
0.0 0.0 GO:0019255 glucose 1-phosphate metabolic process(GO:0019255)
0.0 0.0 GO:0040016 embryonic cleavage(GO:0040016)
0.0 0.1 GO:0033261 obsolete regulation of S phase(GO:0033261)
0.0 0.0 GO:0048312 intracellular distribution of mitochondria(GO:0048312)
0.0 0.1 GO:0007386 compartment pattern specification(GO:0007386)
0.0 0.2 GO:0050702 interleukin-1 beta secretion(GO:0050702)
0.0 0.1 GO:0043984 histone H4-K16 acetylation(GO:0043984)
0.0 0.0 GO:0071379 cellular response to prostaglandin stimulus(GO:0071379)
0.0 0.0 GO:0045578 negative regulation of B cell differentiation(GO:0045578)
0.0 0.1 GO:0030174 regulation of DNA-dependent DNA replication initiation(GO:0030174)
0.0 0.1 GO:0016322 neuron remodeling(GO:0016322)
0.0 0.0 GO:0060235 lens induction in camera-type eye(GO:0060235)
0.0 0.0 GO:0060596 mammary placode formation(GO:0060596)
0.0 0.0 GO:0033152 immunoglobulin V(D)J recombination(GO:0033152)
0.0 0.1 GO:0010886 positive regulation of cholesterol storage(GO:0010886)
0.0 0.0 GO:0030854 positive regulation of granulocyte differentiation(GO:0030854)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0043218 compact myelin(GO:0043218)
0.0 0.0 GO:0000942 condensed nuclear chromosome outer kinetochore(GO:0000942)
0.0 0.0 GO:0072487 MSL complex(GO:0072487)
0.0 0.1 GO:0001931 uropod(GO:0001931) cell trailing edge(GO:0031254)
0.0 0.1 GO:0042101 T cell receptor complex(GO:0042101)
0.0 0.1 GO:0034362 low-density lipoprotein particle(GO:0034362)
0.0 0.0 GO:0042405 nuclear inclusion body(GO:0042405)
0.0 0.1 GO:0035098 ESC/E(Z) complex(GO:0035098)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0001159 RNA polymerase II core promoter proximal region sequence-specific DNA binding(GO:0000978) core promoter proximal region sequence-specific DNA binding(GO:0000987) core promoter proximal region DNA binding(GO:0001159)
0.0 0.2 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.0 0.1 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.0 0.1 GO:0005315 inorganic phosphate transmembrane transporter activity(GO:0005315)
0.0 0.1 GO:0004833 tryptophan 2,3-dioxygenase activity(GO:0004833)
0.0 0.1 GO:0016308 1-phosphatidylinositol-4-phosphate 5-kinase activity(GO:0016308)
0.0 0.1 GO:0004875 complement receptor activity(GO:0004875)
0.0 0.2 GO:0032452 histone demethylase activity(GO:0032452)
0.0 0.1 GO:0016635 oxidoreductase activity, acting on the CH-CH group of donors, quinone or related compound as acceptor(GO:0016635)
0.0 0.1 GO:0046934 phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) phosphatidylinositol bisphosphate kinase activity(GO:0052813)
0.0 0.0 GO:0004465 lipoprotein lipase activity(GO:0004465)
0.0 0.1 GO:0004716 receptor signaling protein tyrosine kinase activity(GO:0004716)
0.0 0.0 GO:0047499 calcium-independent phospholipase A2 activity(GO:0047499)
0.0 0.0 GO:0019834 phospholipase A2 inhibitor activity(GO:0019834)
0.0 0.0 GO:0035184 histone threonine kinase activity(GO:0035184)
0.0 0.0 GO:0019763 immunoglobulin receptor activity(GO:0019763)
0.0 0.0 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.0 0.0 GO:0004814 arginine-tRNA ligase activity(GO:0004814)
0.0 0.2 GO:0030169 low-density lipoprotein particle binding(GO:0030169)
0.0 0.1 GO:0004908 interleukin-1 receptor activity(GO:0004908)
0.0 0.1 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
0.0 0.1 GO:0004614 phosphoglucomutase activity(GO:0004614)
0.0 0.0 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.0 0.0 GO:0042285 UDP-xylosyltransferase activity(GO:0035252) xylosyltransferase activity(GO:0042285)
0.0 0.1 GO:0042834 peptidoglycan binding(GO:0042834)
0.0 0.0 GO:0004974 leukotriene receptor activity(GO:0004974)
0.0 0.0 GO:0008420 CTD phosphatase activity(GO:0008420)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.0 PID HDAC CLASSII PATHWAY Signaling events mediated by HDAC Class II
0.0 0.2 SA PTEN PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.0 0.0 REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.0 0.0 REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE Genes involved in Translocation of ZAP-70 to Immunological synapse
0.0 0.4 REACTOME GPVI MEDIATED ACTIVATION CASCADE Genes involved in GPVI-mediated activation cascade
0.0 0.1 REACTOME CD28 DEPENDENT VAV1 PATHWAY Genes involved in CD28 dependent Vav1 pathway
0.0 0.1 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.0 0.2 REACTOME INFLAMMASOMES Genes involved in Inflammasomes