Project
ENCODE: H3K4me1 ChIP-Seq of primary human cells
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CREMA is a free online tool that recognizes most important transcription factors that change the chromatin state across different samples.

Results for PPARA

Z-value: 1.23

Motif logo

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Transcription factors associated with PPARA

Gene Symbol Gene ID Gene Info
ENSG00000186951.12 PPARA

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE Gene Distance Association probability Pearson corr. coef. P-value Plot
PPARAchr22_46559507_46559658117950.140384-0.713.1e-02Click!
PPARAchr22_46581334_4658148587640.159407-0.656.0e-02Click!
PPARAchr22_46544761_4654499515460.297004-0.541.3e-01Click!
PPARAchr22_46547537_465478321030.953871-0.422.6e-01Click!
PPARAchr22_46615753_46615904215470.130060-0.412.7e-01Click!

Activity of the PPARA motif across conditions

Conditions sorted by the z-value of the PPARA motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE) Target Score Top associated gene Gene Info Distance of CRE to TSS CRE/Gene association probability
chr5_150023934_150024085 0.41 SYNPO
synaptopodin
3769
0.18
chr17_983655_983915 0.41 ABR
active BCR-related
1399
0.45
chr3_111456267_111456418 0.39 PHLDB2
pleckstrin homology-like domain, family B, member 2
4998
0.26
chr7_107590153_107590304 0.39 CTB-13F3.1

7667
0.2
chr22_36748127_36749442 0.38 MYH9
myosin, heavy chain 9, non-muscle
12372
0.18
chr3_53184032_53184571 0.37 PRKCD
protein kinase C, delta
5724
0.19
chr8_94849897_94850048 0.37 TMEM67
transmembrane protein 67
52475
0.1
chr14_55117533_55117800 0.36 SAMD4A
sterile alpha motif domain containing 4A
83029
0.09
chr5_169172919_169173070 0.35 DOCK2
dedicator of cytokinesis 2
13727
0.24
chr11_122052864_122053015 0.35 ENSG00000207994
.
29923
0.15
chr15_74232933_74233272 0.35 LOXL1-AS1
LOXL1 antisense RNA 1
12513
0.14
chr11_35651062_35651213 0.35 FJX1
four jointed box 1 (Drosophila)
11402
0.23
chr1_27449027_27449223 0.34 SLC9A1
solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1
31848
0.16
chr10_105610194_105610481 0.33 SH3PXD2A
SH3 and PX domains 2A
4827
0.22
chr9_130297815_130297966 0.32 FAM129B
family with sequence similarity 129, member B
33477
0.12
chr11_10346579_10346730 0.31 AMPD3
adenosine monophosphate deaminase 3
7436
0.17
chr19_4063421_4064204 0.31 CTD-2622I13.3

1065
0.34
chr1_215550097_215550248 0.31 KCTD3
potassium channel tetramerization domain containing 3
190563
0.03
chr2_1576006_1576157 0.30 AC144450.1

47804
0.16
chr1_172897360_172897511 0.30 TNFSF18
tumor necrosis factor (ligand) superfamily, member 18
122621
0.06
chr17_3892192_3892343 0.30 ATP2A3
ATPase, Ca++ transporting, ubiquitous
24531
0.15
chr2_192731249_192731546 0.30 SDPR
serum deprivation response
19416
0.21
chr5_53683581_53683732 0.29 HSPB3
heat shock 27kDa protein 3
67789
0.12
chr13_30595393_30595581 0.29 LINC00572
long intergenic non-protein coding RNA 572
94699
0.09
chr1_159567510_159567661 0.29 APCS
amyloid P component, serum
9970
0.22
chr13_43860512_43860663 0.29 ENOX1
ecto-NOX disulfide-thiol exchanger 1
74626
0.13
chr12_110975783_110975934 0.29 RAD9B
RAD9 homolog B (S. pombe)
35739
0.1
chr1_66943315_66943466 0.29 SGIP1
SH3-domain GRB2-like (endophilin) interacting protein 1
55676
0.15
chr2_67096492_67096643 0.29 MEIS1
Meis homeobox 1
360508
0.01
chr5_54206170_54206321 0.29 RP11-45H22.3
Uncharacterized protein
47429
0.13
chr11_101329307_101329458 0.29 ENSG00000263885
.
61254
0.15
chr6_33669541_33669692 0.29 ENSG00000266509
.
3711
0.17
chr11_8084807_8084958 0.28 RP11-236J17.5

3297
0.19
chr19_47128911_47129399 0.28 PTGIR
prostaglandin I2 (prostacyclin) receptor (IP)
780
0.43
chr3_66033537_66033688 0.28 MAGI1
membrane associated guanylate kinase, WW and PDZ domain containing 1
9387
0.23
chr6_24743342_24743493 0.28 C6orf62
chromosome 6 open reading frame 62
22353
0.12
chr2_43152776_43153425 0.28 HAAO
3-hydroxyanthranilate 3,4-dioxygenase
133368
0.05
chr1_61456509_61456660 0.28 RP4-668G5.1

20136
0.24
chr17_71285096_71285247 0.28 CDC42EP4
CDC42 effector protein (Rho GTPase binding) 4
22376
0.14
chr1_246584704_246584855 0.27 SMYD3
SET and MYND domain containing 3
4065
0.24
chr12_122835503_122835654 0.27 CLIP1
CAP-GLY domain containing linker protein 1
12986
0.22
chr22_30604075_30604921 0.27 RP3-438O4.4

1400
0.33
chr18_25763676_25763827 0.27 CDH2
cadherin 2, type 1, N-cadherin (neuronal)
6341
0.35
chr6_169474932_169475083 0.27 XXyac-YX65C7_A.2

138342
0.05
chr11_12307843_12308146 0.27 MICALCL
MICAL C-terminal like
453
0.82
chr20_30130007_30130314 0.27 HM13-IT1
HM13 intronic transcript 1 (non-protein coding)
20809
0.11
chr5_54457577_54457728 0.27 GPX8
glutathione peroxidase 8 (putative)
1654
0.24
chr6_168358018_168358169 0.27 MLLT4
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 4
5464
0.27
chr15_58734384_58734535 0.27 LIPC
lipase, hepatic
10269
0.2
chr4_119697437_119697588 0.27 SEC24D
SEC24 family member D
6517
0.29
chr3_159744998_159745380 0.27 LINC01100
long intergenic non-protein coding RNA 1100
11378
0.19
chr4_157897574_157897725 0.27 PDGFC
platelet derived growth factor C
5103
0.24
chr3_55450202_55450353 0.27 WNT5A
wingless-type MMTV integration site family, member 5A
64947
0.14
chr11_65185776_65186435 0.26 ENSG00000245532
.
25824
0.09
chr16_31009950_31010101 0.26 STX1B
syntaxin 1B
2251
0.14
chr8_41906632_41907752 0.26 KAT6A
K(lysine) acetyltransferase 6A
2313
0.3
chr14_101308246_101309004 0.26 ENSG00000214548
.
7020
0.04
chr6_43677467_43677618 0.26 MRPS18A
mitochondrial ribosomal protein S18A
22014
0.14
chr16_70737707_70738175 0.26 VAC14
Vac14 homolog (S. cerevisiae)
3793
0.18
chr12_76208805_76209260 0.26 ENSG00000264062
.
90711
0.08
chr3_157246321_157246472 0.26 VEPH1
ventricular zone expressed PH domain-containing 1
4999
0.26
chr3_137762283_137762711 0.26 DZIP1L
DAZ interacting zinc finger protein 1-like
23985
0.17
chr15_75995798_75996054 0.26 CSPG4
chondroitin sulfate proteoglycan 4
9263
0.1
chr11_33713061_33713264 0.26 RP4-541C22.5

5085
0.19
chr3_16166790_16167040 0.26 GALNT15
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 15
49241
0.16
chr2_47074710_47074982 0.26 AC016722.3

5789
0.17
chr17_40673744_40674238 0.25 ENSG00000265611
.
7785
0.08
chr14_100222322_100222621 0.25 EML1
echinoderm microtubule associated protein like 1
16815
0.21
chr5_167740954_167741105 0.25 WWC1
WW and C2 domain containing 1
21874
0.23
chr8_50968622_50968921 0.25 SNTG1
syntrophin, gamma 1
144066
0.05
chr1_27326361_27326655 0.25 TRNP1
TMF1-regulated nuclear protein 1
5698
0.16
chr12_69893020_69893171 0.25 FRS2
fibroblast growth factor receptor substrate 2
28881
0.18
chr9_133837632_133837801 0.25 FIBCD1
fibrinogen C domain containing 1
23189
0.15
chr17_462712_462863 0.25 RP5-1029F21.2

6981
0.2
chr9_738796_739027 0.24 KANK1
KN motif and ankyrin repeat domains 1
6295
0.26
chr2_62803521_62803672 0.24 TMEM17
transmembrane protein 17
70120
0.1
chr5_9060446_9060790 0.24 ENSG00000266415
.
6611
0.3
chr1_17559878_17560367 0.24 PADI1
peptidyl arginine deiminase, type I
272
0.9
chr1_31870163_31870721 0.24 SERINC2
serine incorporator 2
11970
0.15
chr2_36677747_36677898 0.24 CRIM1
cysteine rich transmembrane BMP regulator 1 (chordin-like)
63011
0.12
chr17_19806867_19807136 0.24 RP11-209D14.4

26049
0.15
chr3_187952552_187952703 0.24 LPP
LIM domain containing preferred translocation partner in lipoma
5025
0.29
chr6_151380765_151381332 0.24 RP1-292B18.3

3855
0.23
chr8_42053315_42053519 0.24 PLAT
plasminogen activator, tissue
201
0.93
chr9_125145904_125146116 0.24 AL162424.1
Uncharacterized protein
2918
0.17
chr2_9571047_9571198 0.24 CPSF3
cleavage and polyadenylation specific factor 3, 73kDa
7109
0.19
chr2_241861351_241861530 0.24 AC104809.3
Protein LOC728763
546
0.72
chr6_160457258_160457573 0.24 AIRN
antisense of IGF2R non-protein coding RNA
28719
0.19
chr2_19323725_19323876 0.24 ENSG00000266738
.
224390
0.02
chr20_49962411_49962562 0.23 ENSG00000263645
.
31372
0.22
chr17_2084323_2084474 0.23 SMG6
SMG6 nonsense mediated mRNA decay factor
7926
0.13
chr3_124827683_124827880 0.23 ENSG00000199327
.
10263
0.17
chr9_83646594_83646895 0.23 ENSG00000221581
.
297500
0.01
chr11_45880222_45880373 0.23 CRY2
cryptochrome 2 (photolyase-like)
11340
0.14
chr7_116074476_116074627 0.23 ENSG00000252672
.
1283
0.46
chr17_17642775_17643230 0.23 RAI1-AS1
RAI1 antisense RNA 1
31133
0.12
chr5_90458223_90458626 0.23 ENSG00000199643
.
108120
0.08
chr4_129376493_129376739 0.23 PGRMC2
progesterone receptor membrane component 2
166632
0.04
chr12_116827438_116827589 0.23 ENSG00000264037
.
38610
0.19
chr6_3518009_3518229 0.23 SLC22A23
solute carrier family 22, member 23
60863
0.14
chr13_30095383_30095797 0.23 MTUS2-AS1
MTUS2 antisense RNA 1
31348
0.21
chr8_104357440_104357846 0.23 CTHRC1
collagen triple helix repeat containing 1
26100
0.13
chr17_36031578_36031729 0.23 DDX52
DEAD (Asp-Glu-Ala-Asp) box polypeptide 52
28160
0.14
chr10_33484951_33485102 0.23 NRP1
neuropilin 1
6897
0.23
chr9_81835383_81835534 0.23 TLE4
transducin-like enhancer of split 4 (E(sp1) homolog, Drosophila)
351230
0.01
chr20_48754691_48754842 0.23 TMEM189
transmembrane protein 189
7097
0.18
chr4_57981219_57981370 0.23 IGFBP7
insulin-like growth factor binding protein 7
4743
0.19
chr2_9777860_9778099 0.23 YWHAQ
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta
6836
0.21
chr17_19967902_19968053 0.23 SPECC1
sperm antigen with calponin homology and coiled-coil domains 1
22357
0.18
chr9_97683979_97684130 0.23 RP11-54O15.3

13174
0.18
chr9_132949422_132949573 0.23 NCS1
neuronal calcium sensor 1
13375
0.21
chr7_40509443_40509735 0.23 AC004988.1

76938
0.12
chr2_107561302_107561453 0.23 ST6GAL2
ST6 beta-galactosamide alpha-2,6-sialyltranferase 2
57813
0.15
chr15_80466917_80467209 0.23 FAH
fumarylacetoacetate hydrolase (fumarylacetoacetase)
18770
0.21
chr10_33581429_33581580 0.23 ENSG00000244356
.
3975
0.29
chr7_51113246_51113397 0.23 RP4-724E13.2

28161
0.24
chr5_57134689_57134840 0.23 ENSG00000266864
.
34109
0.24
chr7_130934065_130934342 0.23 MKLN1
muskelin 1, intracellular mediator containing kelch motifs
35618
0.2
chr11_66735383_66735534 0.23 C11orf86
chromosome 11 open reading frame 86
7290
0.13
chr1_162939578_162939729 0.23 RGS4
regulator of G-protein signaling 4
98912
0.07
chr20_25506429_25506580 0.22 NINL
ninein-like
46841
0.14
chr2_47270470_47270778 0.22 AC093732.1

2961
0.26
chr10_14027008_14027165 0.22 RP11-142M10.2

6729
0.23
chr16_85244563_85244846 0.22 CTC-786C10.1

39822
0.17
chr20_25213904_25214055 0.22 AL035252.1
HCG2018895; Uncharacterized protein
6609
0.16
chr3_45687605_45688015 0.22 LIMD1-AS1
LIMD1 antisense RNA 1
42564
0.12
chr6_25193185_25193336 0.22 ENSG00000222373
.
619
0.73
chr9_71746145_71746296 0.22 TJP2
tight junction protein 2
9996
0.26
chr22_46629173_46629500 0.22 CDPF1
cysteine-rich, DPF motif domain containing 1
14846
0.14
chr4_13923259_13923557 0.22 ENSG00000252092
.
263157
0.02
chr7_30209199_30209350 0.22 AC007036.5

12127
0.17
chr3_124578176_124578400 0.22 ITGB5
integrin, beta 5
10990
0.22
chr3_115508519_115508795 0.22 ENSG00000243359
.
48058
0.19
chr12_65931558_65931709 0.22 MSRB3
methionine sulfoxide reductase B3
210978
0.02
chr15_99994749_99995202 0.22 MEF2A
myocyte enhancer factor 2A
22395
0.18
chr15_73979990_73980141 0.22 CD276
CD276 molecule
2718
0.32
chr12_2411461_2411612 0.22 CACNA1C-IT3
CACNA1C intronic transcript 3 (non-protein coding)
32594
0.21
chr16_85169897_85170486 0.22 FAM92B
family with sequence similarity 92, member B
24077
0.18
chr8_13472951_13473102 0.22 RP11-145O15.3

10907
0.24
chr13_43843803_43843954 0.22 ENOX1
ecto-NOX disulfide-thiol exchanger 1
91335
0.1
chr2_191910102_191910403 0.22 ENSG00000231858
.
24000
0.15
chr5_125808507_125808658 0.22 RP11-517I3.1

5259
0.23
chr2_192251959_192252110 0.22 MYO1B
myosin IB
4826
0.27
chr22_36720442_36720593 0.22 ENSG00000266345
.
8271
0.19
chr10_128555614_128555817 0.22 DOCK1
dedicator of cytokinesis 1
38263
0.18
chr3_112365560_112365711 0.22 CCDC80
coiled-coil domain containing 80
5488
0.27
chr14_61719164_61719445 0.22 ENSG00000252380
.
10446
0.19
chr22_37908037_37908429 0.22 CARD10
caspase recruitment domain family, member 10
15
0.97
chr2_175426252_175426403 0.22 ENSG00000206965
.
3527
0.2
chr2_161085952_161086103 0.22 ITGB6
integrin, beta 6
29212
0.24
chr15_74472280_74472489 0.22 RP11-665J16.1

817
0.48
chr10_105409169_105409599 0.22 SH3PXD2A
SH3 and PX domains 2A
12078
0.17
chr6_85349444_85349595 0.22 RP11-132M7.3

49624
0.19
chr16_29283837_29283988 0.22 RP11-231C14.6

39759
0.13
chr22_44417253_44417404 0.21 PARVB
parvin, beta
2829
0.32
chr18_43381728_43382214 0.21 SIGLEC15
sialic acid binding Ig-like lectin 15
23506
0.18
chr18_9536603_9536773 0.21 RP11-61L19.3

17241
0.14
chr10_73292337_73292498 0.21 CDH23-AS1
CDH23 antisense RNA 1
20787
0.22
chr12_123429411_123429620 0.21 ABCB9
ATP-binding cassette, sub-family B (MDR/TAP), member 9
293
0.88
chr3_15978129_15978418 0.21 ENSG00000207815
.
62995
0.12
chr8_122612704_122612855 0.21 HAS2-AS1
HAS2 antisense RNA 1
38754
0.17
chr11_113545454_113545605 0.21 TMPRSS5
transmembrane protease, serine 5
31495
0.18
chr15_101265712_101265890 0.21 ENSG00000212306
.
87233
0.08
chr2_151330521_151330720 0.21 RND3
Rho family GTPase 3
11276
0.33
chr6_128888462_128888749 0.21 ENSG00000206982
.
16930
0.18
chr7_55121133_55121284 0.21 EGFR
epidermal growth factor receptor
34397
0.22
chr5_67614932_67615223 0.21 PIK3R1
phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
26681
0.26
chr17_43201649_43202065 0.21 PLCD3
phospholipase C, delta 3
5478
0.11
chr6_139729934_139730085 0.21 CITED2
Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2
34252
0.22
chr12_66262478_66262882 0.21 ENSG00000211577
.
10887
0.18
chr3_149738658_149738809 0.21 PFN2
profilin 2
1865
0.34
chr13_76345505_76345656 0.21 LMO7
LIM domain 7
10783
0.26
chr12_88826923_88827100 0.21 ENSG00000199245
.
2792
0.4
chr5_77800136_77800667 0.21 LHFPL2
lipoma HMGIC fusion partner-like 2
44573
0.19
chr7_93927196_93927476 0.21 COL1A2
collagen, type I, alpha 2
96537
0.08
chr5_138397564_138397715 0.21 SIL1
SIL1 nucleotide exchange factor
19268
0.18
chr5_66563655_66563806 0.21 CD180
CD180 molecule
71103
0.13
chr20_49983402_49983553 0.21 ENSG00000263645
.
10381
0.28
chr12_127726319_127726470 0.21 ENSG00000239776
.
75722
0.12
chr4_129439255_129439511 0.21 PGRMC2
progesterone receptor membrane component 2
229399
0.02
chr6_169692156_169692309 0.21 THBS2
thrombospondin 2
38093
0.21
chr11_86169965_86170116 0.21 RP11-317J19.1

27408
0.2
chr13_40105934_40106139 0.21 LHFP
lipoma HMGIC fusion partner
71272
0.11
chr5_133774585_133774736 0.21 CDKN2AIPNL
CDKN2A interacting protein N-terminal like
27071
0.14
chr5_134581591_134581861 0.21 C5orf66
chromosome 5 open reading frame 66
91903
0.08
chr6_123119419_123119570 0.21 SMPDL3A
sphingomyelin phosphodiesterase, acid-like 3A
9023
0.21
chr16_84261598_84261886 0.21 KCNG4
potassium voltage-gated channel, subfamily G, member 4
11562
0.12
chr12_105186825_105187144 0.21 ENSG00000222579
.
58618
0.14
chr15_63031651_63031802 0.21 TLN2
talin 2
12437
0.2
chr5_73233761_73233912 0.21 ARHGEF28
Rho guanine nucleotide exchange factor (GEF) 28
52108
0.16
chr21_43460258_43460538 0.21 UMODL1
uromodulin-like 1
22670
0.16
chr11_113601597_113601748 0.21 TMPRSS5
transmembrane protease, serine 5
24577
0.15
chr10_22723256_22723780 0.21 RP11-301N24.3

73417
0.1
chr17_77034391_77034542 0.21 C1QTNF1
C1q and tumor necrosis factor related protein 1
3342
0.18
chr5_72618413_72618564 0.21 FOXD1
forkhead box D1
125864
0.05
chr9_130323275_130323553 0.21 FAM129B
family with sequence similarity 129, member B
7953
0.18
chr6_41549730_41549995 0.21 FOXP4
forkhead box P4
11950
0.15
chr14_92864210_92864675 0.21 SLC24A4
solute carrier family 24 (sodium/potassium/calcium exchanger), member 4
10281
0.28
chr6_39855140_39855437 0.20 RP11-61I13.3

944
0.63
chr4_125124885_125125036 0.20 ANKRD50
ankyrin repeat domain 50
508927
0.0

Histogram of CRE-TSS distances for CREs targeted by :

Histogram of

Rank distribution of CRE target scores:

Histogram of target CRE score.

Distribution of target CREs across different genomic regions:

Weighted Piechart of Weighted Piechart of Weighted Piechart of

Network of associatons between targets according to the STRING database.

StringDB image

First level regulatory network of PPARA

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.5 GO:0060666 dichotomous subdivision of terminal units involved in salivary gland branching(GO:0060666)
0.1 0.1 GO:0051898 negative regulation of protein kinase B signaling(GO:0051898)
0.1 0.3 GO:0055098 response to low-density lipoprotein particle(GO:0055098)
0.1 0.3 GO:0051497 negative regulation of stress fiber assembly(GO:0051497)
0.1 0.3 GO:0043589 skin morphogenesis(GO:0043589)
0.1 0.3 GO:0097531 mast cell chemotaxis(GO:0002551) regulation of mast cell chemotaxis(GO:0060753) positive regulation of mast cell chemotaxis(GO:0060754) mast cell migration(GO:0097531)
0.1 0.3 GO:0030644 cellular chloride ion homeostasis(GO:0030644) chloride ion homeostasis(GO:0055064)
0.1 0.3 GO:0018101 protein citrullination(GO:0018101)
0.1 0.2 GO:0051124 synaptic growth at neuromuscular junction(GO:0051124)
0.1 0.2 GO:0009128 purine nucleoside monophosphate catabolic process(GO:0009128) ribonucleoside monophosphate catabolic process(GO:0009158) purine ribonucleoside monophosphate catabolic process(GO:0009169)
0.1 0.2 GO:0005997 xylulose metabolic process(GO:0005997)
0.1 0.2 GO:0032509 endosome transport via multivesicular body sorting pathway(GO:0032509)
0.1 0.2 GO:0060013 righting reflex(GO:0060013)
0.1 0.2 GO:0071436 sodium ion export(GO:0071436)
0.1 0.1 GO:0015868 purine ribonucleotide transport(GO:0015868)
0.1 0.2 GO:0045077 negative regulation of interferon-gamma biosynthetic process(GO:0045077)
0.0 0.1 GO:0019511 peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401) 4-hydroxyproline metabolic process(GO:0019471) peptidyl-proline hydroxylation(GO:0019511)
0.0 0.3 GO:0007171 activation of transmembrane receptor protein tyrosine kinase activity(GO:0007171)
0.0 0.1 GO:0007352 zygotic specification of dorsal/ventral axis(GO:0007352)
0.0 0.2 GO:0015889 cobalamin transport(GO:0015889)
0.0 0.1 GO:0061525 hindgut morphogenesis(GO:0007442) hindgut development(GO:0061525)
0.0 0.1 GO:0002072 optic cup morphogenesis involved in camera-type eye development(GO:0002072)
0.0 0.1 GO:0060083 smooth muscle contraction involved in micturition(GO:0060083)
0.0 0.2 GO:0006654 phosphatidic acid biosynthetic process(GO:0006654)
0.0 0.1 GO:0010193 response to ozone(GO:0010193)
0.0 0.3 GO:0035413 positive regulation of catenin import into nucleus(GO:0035413)
0.0 0.1 GO:0000212 meiotic spindle organization(GO:0000212)
0.0 0.1 GO:0001973 adenosine receptor signaling pathway(GO:0001973) G-protein coupled purinergic receptor signaling pathway(GO:0035588)
0.0 0.1 GO:0034638 phosphatidylcholine catabolic process(GO:0034638)
0.0 0.4 GO:0007016 cytoskeletal anchoring at plasma membrane(GO:0007016)
0.0 0.1 GO:0001996 positive regulation of heart rate by epinephrine-norepinephrine(GO:0001996)
0.0 0.1 GO:0032277 negative regulation of gonadotropin secretion(GO:0032277)
0.0 0.2 GO:0048702 embryonic neurocranium morphogenesis(GO:0048702)
0.0 0.1 GO:0060831 smoothened signaling pathway involved in dorsal/ventral neural tube patterning(GO:0060831)
0.0 0.1 GO:0060900 embryonic camera-type eye formation(GO:0060900)
0.0 0.2 GO:0001554 luteolysis(GO:0001554)
0.0 0.1 GO:0070427 nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070427)
0.0 0.2 GO:0061081 positive regulation of myeloid leukocyte cytokine production involved in immune response(GO:0061081)
0.0 0.1 GO:0001778 plasma membrane repair(GO:0001778)
0.0 0.1 GO:0051005 negative regulation of lipoprotein lipase activity(GO:0051005)
0.0 0.2 GO:0015937 coenzyme A biosynthetic process(GO:0015937)
0.0 0.1 GO:0035234 ectopic germ cell programmed cell death(GO:0035234)
0.0 0.4 GO:0035329 hippo signaling(GO:0035329)
0.0 0.1 GO:0060129 thyroid-stimulating hormone-secreting cell differentiation(GO:0060129)
0.0 0.2 GO:0016264 gap junction assembly(GO:0016264)
0.0 0.3 GO:0006853 carnitine shuttle(GO:0006853) carnitine transmembrane transport(GO:1902603)
0.0 0.1 GO:0002043 blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:0002043)
0.0 0.1 GO:0010803 regulation of tumor necrosis factor-mediated signaling pathway(GO:0010803)
0.0 0.1 GO:0022605 oogenesis stage(GO:0022605)
0.0 0.0 GO:0060028 convergent extension involved in axis elongation(GO:0060028)
0.0 0.1 GO:1900116 sequestering of extracellular ligand from receptor(GO:0035581) sequestering of TGFbeta in extracellular matrix(GO:0035583) protein localization to extracellular region(GO:0071692) maintenance of protein location in extracellular region(GO:0071694) extracellular regulation of signal transduction(GO:1900115) extracellular negative regulation of signal transduction(GO:1900116)
0.0 0.1 GO:0009414 response to water deprivation(GO:0009414)
0.0 0.1 GO:0007028 cytoplasm organization(GO:0007028)
0.0 0.3 GO:0031116 positive regulation of microtubule polymerization(GO:0031116)
0.0 0.1 GO:0010447 response to acidic pH(GO:0010447)
0.0 0.1 GO:0048343 paraxial mesodermal cell differentiation(GO:0048342) paraxial mesodermal cell fate commitment(GO:0048343)
0.0 0.1 GO:0033173 calcineurin-NFAT signaling cascade(GO:0033173)
0.0 0.1 GO:0032467 positive regulation of cytokinesis(GO:0032467)
0.0 0.1 GO:0033603 positive regulation of dopamine secretion(GO:0033603)
0.0 0.1 GO:0052305 pathogen-associated molecular pattern dependent induction by symbiont of host innate immune response(GO:0052033) positive regulation by symbiont of host innate immune response(GO:0052166) modulation by symbiont of host innate immune response(GO:0052167) pathogen-associated molecular pattern dependent modulation by symbiont of host innate immune response(GO:0052169) pathogen-associated molecular pattern dependent induction by organism of innate immune response of other organism involved in symbiotic interaction(GO:0052257) positive regulation by organism of innate immune response in other organism involved in symbiotic interaction(GO:0052305) modulation by organism of innate immune response in other organism involved in symbiotic interaction(GO:0052306) pathogen-associated molecular pattern dependent modulation by organism of innate immune response in other organism involved in symbiotic interaction(GO:0052308)
0.0 0.1 GO:0007386 compartment pattern specification(GO:0007386)
0.0 0.1 GO:0046532 regulation of photoreceptor cell differentiation(GO:0046532)
0.0 0.1 GO:0007221 positive regulation of transcription of Notch receptor target(GO:0007221)
0.0 0.1 GO:0032344 regulation of ketone biosynthetic process(GO:0010566) regulation of aldosterone metabolic process(GO:0032344) regulation of aldosterone biosynthetic process(GO:0032347)
0.0 0.1 GO:0006562 proline catabolic process(GO:0006562)
0.0 0.1 GO:0050703 interleukin-1 alpha secretion(GO:0050703)
0.0 0.2 GO:0031272 pseudopodium assembly(GO:0031269) regulation of pseudopodium assembly(GO:0031272) positive regulation of pseudopodium assembly(GO:0031274)
0.0 0.1 GO:0048861 leukemia inhibitory factor signaling pathway(GO:0048861)
0.0 0.1 GO:0032780 negative regulation of ATPase activity(GO:0032780)
0.0 0.1 GO:0061302 smooth muscle cell-matrix adhesion(GO:0061302)
0.0 0.1 GO:0060014 granulosa cell differentiation(GO:0060014)
0.0 0.1 GO:0006572 tyrosine catabolic process(GO:0006572)
0.0 0.1 GO:0006533 aspartate metabolic process(GO:0006531) aspartate catabolic process(GO:0006533)
0.0 0.0 GO:0045627 positive regulation of T-helper 1 cell differentiation(GO:0045627)
0.0 0.1 GO:0042504 tyrosine phosphorylation of Stat4 protein(GO:0042504) regulation of tyrosine phosphorylation of Stat4 protein(GO:0042519) positive regulation of tyrosine phosphorylation of Stat4 protein(GO:0042520)
0.0 0.0 GO:0030210 heparin metabolic process(GO:0030202) heparin biosynthetic process(GO:0030210)
0.0 0.1 GO:2000054 negative regulation of Wnt signaling pathway involved in dorsal/ventral axis specification(GO:2000054)
0.0 0.0 GO:0045715 negative regulation of low-density lipoprotein particle receptor biosynthetic process(GO:0045715)
0.0 0.0 GO:0045162 clustering of voltage-gated sodium channels(GO:0045162)
0.0 0.1 GO:0003283 atrial septum development(GO:0003283) atrial septum morphogenesis(GO:0060413)
0.0 0.0 GO:0061047 foregut regionalization(GO:0060423) lung field specification(GO:0060424) lung induction(GO:0060492) positive regulation of branching involved in lung morphogenesis(GO:0061047)
0.0 0.0 GO:0071379 cellular response to prostaglandin stimulus(GO:0071379)
0.0 0.1 GO:0010901 regulation of very-low-density lipoprotein particle remodeling(GO:0010901)
0.0 0.1 GO:0045112 integrin biosynthetic process(GO:0045112)
0.0 0.1 GO:0007619 courtship behavior(GO:0007619)
0.0 0.0 GO:0048388 endosomal lumen acidification(GO:0048388)
0.0 0.1 GO:0001955 blood vessel maturation(GO:0001955)
0.0 0.1 GO:0048596 embryonic camera-type eye morphogenesis(GO:0048596)
0.0 0.1 GO:0009756 carbohydrate mediated signaling(GO:0009756)
0.0 0.1 GO:0090023 positive regulation of neutrophil chemotaxis(GO:0090023) positive regulation of neutrophil migration(GO:1902624)
0.0 0.0 GO:0007500 mesodermal cell fate determination(GO:0007500)
0.0 0.1 GO:0042090 interleukin-12 biosynthetic process(GO:0042090) regulation of interleukin-12 biosynthetic process(GO:0045075)
0.0 0.0 GO:0070272 proton-transporting ATP synthase complex assembly(GO:0043461) proton-transporting ATP synthase complex biogenesis(GO:0070272)
0.0 0.1 GO:0071364 cellular response to epidermal growth factor stimulus(GO:0071364)
0.0 0.0 GO:0032488 Cdc42 protein signal transduction(GO:0032488)
0.0 0.0 GO:0033622 integrin activation(GO:0033622)
0.0 0.1 GO:0008218 bioluminescence(GO:0008218)
0.0 0.1 GO:0090073 positive regulation of protein homodimerization activity(GO:0090073)
0.0 0.1 GO:0033600 negative regulation of mammary gland epithelial cell proliferation(GO:0033600)
0.0 0.1 GO:0072048 pattern specification involved in kidney development(GO:0061004) renal system pattern specification(GO:0072048) pattern specification involved in metanephros development(GO:0072268)
0.0 0.1 GO:0090136 epithelial cell-cell adhesion(GO:0090136)
0.0 0.1 GO:0072216 positive regulation of metanephros development(GO:0072216)
0.0 0.1 GO:0007412 axon target recognition(GO:0007412)
0.0 0.0 GO:0048368 lateral mesoderm development(GO:0048368)
0.0 0.0 GO:0051088 PMA-inducible membrane protein ectodomain proteolysis(GO:0051088)
0.0 0.1 GO:0031641 regulation of myelination(GO:0031641)
0.0 0.1 GO:2000095 regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000095)
0.0 0.1 GO:0005981 regulation of glycogen catabolic process(GO:0005981)
0.0 0.1 GO:0001547 antral ovarian follicle growth(GO:0001547)
0.0 0.1 GO:0006927 obsolete transformed cell apoptotic process(GO:0006927)
0.0 0.1 GO:0006701 progesterone biosynthetic process(GO:0006701)
0.0 0.0 GO:0048808 male genitalia morphogenesis(GO:0048808) male anatomical structure morphogenesis(GO:0090598)
0.0 0.1 GO:0033631 cell-cell adhesion mediated by integrin(GO:0033631)
0.0 0.1 GO:0045071 negative regulation of viral genome replication(GO:0045071)
0.0 0.1 GO:0010966 regulation of phosphate transport(GO:0010966)
0.0 0.1 GO:0048149 behavioral response to ethanol(GO:0048149)
0.0 0.0 GO:0051771 negative regulation of nitric-oxide synthase biosynthetic process(GO:0051771)
0.0 0.1 GO:0031340 positive regulation of vesicle fusion(GO:0031340)
0.0 0.0 GO:0060665 regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling(GO:0060665)
0.0 0.1 GO:0048570 notochord morphogenesis(GO:0048570)
0.0 0.0 GO:0045136 development of secondary sexual characteristics(GO:0045136)
0.0 0.1 GO:0006600 creatine metabolic process(GO:0006600)
0.0 0.1 GO:0042693 muscle cell fate commitment(GO:0042693)
0.0 0.0 GO:0032413 negative regulation of ion transmembrane transporter activity(GO:0032413)
0.0 0.0 GO:0032525 somite rostral/caudal axis specification(GO:0032525)
0.0 0.0 GO:0001302 replicative cell aging(GO:0001302)
0.0 0.0 GO:0019530 taurine metabolic process(GO:0019530)
0.0 0.1 GO:0007501 mesodermal cell fate specification(GO:0007501)
0.0 0.0 GO:0043117 positive regulation of vascular permeability(GO:0043117)
0.0 0.1 GO:0015014 heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.0 0.0 GO:0048170 positive regulation of long-term neuronal synaptic plasticity(GO:0048170)
0.0 0.0 GO:0043931 ossification involved in bone maturation(GO:0043931)
0.0 0.0 GO:0006222 UMP biosynthetic process(GO:0006222) pyrimidine ribonucleoside monophosphate metabolic process(GO:0009173) pyrimidine ribonucleoside monophosphate biosynthetic process(GO:0009174) UMP metabolic process(GO:0046049)
0.0 0.0 GO:0021801 cerebral cortex radial glia guided migration(GO:0021801) telencephalon glial cell migration(GO:0022030)
0.0 0.1 GO:0009396 folic acid-containing compound biosynthetic process(GO:0009396)
0.0 0.0 GO:0060059 embryonic retina morphogenesis in camera-type eye(GO:0060059)
0.0 0.2 GO:0009650 UV protection(GO:0009650)
0.0 0.2 GO:0019369 arachidonic acid metabolic process(GO:0019369)
0.0 0.1 GO:0045662 negative regulation of myoblast differentiation(GO:0045662)
0.0 0.1 GO:0010269 response to selenium ion(GO:0010269)
0.0 0.2 GO:0043691 reverse cholesterol transport(GO:0043691)
0.0 0.0 GO:0060762 regulation of branching involved in mammary gland duct morphogenesis(GO:0060762)
0.0 0.1 GO:0045992 negative regulation of embryonic development(GO:0045992)
0.0 0.1 GO:0071731 response to nitric oxide(GO:0071731)
0.0 0.2 GO:0038061 activation of NF-kappaB-inducing kinase activity(GO:0007250) NIK/NF-kappaB signaling(GO:0038061) regulation of NIK/NF-kappaB signaling(GO:1901222) positive regulation of NIK/NF-kappaB signaling(GO:1901224)
0.0 0.1 GO:0001916 positive regulation of T cell mediated cytotoxicity(GO:0001916)
0.0 0.1 GO:0050872 white fat cell differentiation(GO:0050872)
0.0 0.0 GO:0048261 negative regulation of receptor-mediated endocytosis(GO:0048261)
0.0 0.0 GO:0010875 positive regulation of cholesterol efflux(GO:0010875)
0.0 0.4 GO:0048009 insulin-like growth factor receptor signaling pathway(GO:0048009)
0.0 0.0 GO:0070874 negative regulation of glycogen metabolic process(GO:0070874)
0.0 0.1 GO:0046113 nucleobase catabolic process(GO:0046113)
0.0 0.0 GO:0010873 positive regulation of cholesterol esterification(GO:0010873)
0.0 0.0 GO:0001306 age-dependent response to oxidative stress(GO:0001306) age-dependent general metabolic decline(GO:0007571)
0.0 0.1 GO:0072386 plus-end-directed vesicle transport along microtubule(GO:0072383) plus-end-directed organelle transport along microtubule(GO:0072386)
0.0 0.1 GO:0060159 regulation of dopamine receptor signaling pathway(GO:0060159)
0.0 0.0 GO:0055089 fatty acid homeostasis(GO:0055089)
0.0 0.0 GO:0001757 somite specification(GO:0001757)
0.0 0.0 GO:0032410 negative regulation of transporter activity(GO:0032410)
0.0 0.0 GO:0006573 valine metabolic process(GO:0006573)
0.0 0.0 GO:0021631 optic nerve morphogenesis(GO:0021631)
0.0 0.1 GO:0051307 resolution of meiotic recombination intermediates(GO:0000712) meiotic chromosome separation(GO:0051307)
0.0 0.0 GO:0051549 regulation of keratinocyte migration(GO:0051547) positive regulation of keratinocyte migration(GO:0051549)
0.0 0.1 GO:0015840 urea transport(GO:0015840)
0.0 0.1 GO:0051481 negative regulation of cytosolic calcium ion concentration(GO:0051481)
0.0 0.0 GO:0071034 CUT catabolic process(GO:0071034) CUT metabolic process(GO:0071043)
0.0 0.0 GO:0006391 transcription initiation from mitochondrial promoter(GO:0006391)
0.0 0.1 GO:0045717 negative regulation of fatty acid biosynthetic process(GO:0045717)
0.0 0.0 GO:0010919 regulation of inositol phosphate biosynthetic process(GO:0010919) positive regulation of inositol phosphate biosynthetic process(GO:0060732)
0.0 0.0 GO:0021798 forebrain dorsal/ventral pattern formation(GO:0021798)
0.0 0.0 GO:0060433 bronchus development(GO:0060433)
0.0 0.0 GO:0060510 lung saccule development(GO:0060430) Type II pneumocyte differentiation(GO:0060510)
0.0 0.1 GO:0021952 central nervous system projection neuron axonogenesis(GO:0021952)
0.0 0.2 GO:0030866 cortical actin cytoskeleton organization(GO:0030866)
0.0 0.0 GO:0010766 negative regulation of sodium ion transport(GO:0010766)
0.0 0.1 GO:0046719 intracellular transport of viral protein in host cell(GO:0019060) symbiont intracellular protein transport in host(GO:0030581) regulation by virus of viral protein levels in host cell(GO:0046719) intracellular protein transport in other organism involved in symbiotic interaction(GO:0051708)
0.0 0.0 GO:0018094 protein polyglycylation(GO:0018094)
0.0 0.0 GO:0006344 maintenance of chromatin silencing(GO:0006344)
0.0 0.1 GO:0010560 positive regulation of glycoprotein biosynthetic process(GO:0010560) positive regulation of glycoprotein metabolic process(GO:1903020)
0.0 0.0 GO:0032516 positive regulation of phosphoprotein phosphatase activity(GO:0032516)
0.0 0.1 GO:0007185 transmembrane receptor protein tyrosine phosphatase signaling pathway(GO:0007185)
0.0 0.1 GO:0006551 leucine metabolic process(GO:0006551)
0.0 0.0 GO:0061072 iris morphogenesis(GO:0061072)
0.0 0.1 GO:0032329 serine transport(GO:0032329)
0.0 0.0 GO:0010837 regulation of keratinocyte proliferation(GO:0010837)
0.0 0.0 GO:1901889 negative regulation of focal adhesion assembly(GO:0051895) negative regulation of cell junction assembly(GO:1901889) negative regulation of adherens junction organization(GO:1903392)
0.0 0.0 GO:0032342 aldosterone metabolic process(GO:0032341) aldosterone biosynthetic process(GO:0032342) cortisol metabolic process(GO:0034650) cortisol biosynthetic process(GO:0034651)
0.0 0.1 GO:0060997 dendritic spine morphogenesis(GO:0060997) regulation of dendritic spine morphogenesis(GO:0061001) dendritic spine organization(GO:0097061)
0.0 0.1 GO:0032211 negative regulation of telomere maintenance via telomerase(GO:0032211)
0.0 0.0 GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.0 0.1 GO:0050917 sensory perception of umami taste(GO:0050917)
0.0 0.1 GO:0060259 regulation of feeding behavior(GO:0060259)
0.0 0.0 GO:0046476 glycosylceramide biosynthetic process(GO:0046476)
0.0 0.0 GO:0001543 ovarian follicle rupture(GO:0001543)
0.0 0.1 GO:0006020 inositol metabolic process(GO:0006020)
0.0 0.1 GO:0045880 positive regulation of smoothened signaling pathway(GO:0045880)
0.0 0.0 GO:0000103 sulfate assimilation(GO:0000103)
0.0 0.0 GO:0045945 positive regulation of transcription from RNA polymerase III promoter(GO:0045945)
0.0 0.0 GO:0021799 cerebral cortex radially oriented cell migration(GO:0021799)
0.0 0.0 GO:0071549 cellular response to dexamethasone stimulus(GO:0071549) cellular response to ketone(GO:1901655)
0.0 0.0 GO:0071502 cellular response to temperature stimulus(GO:0071502)
0.0 0.0 GO:0015864 pyrimidine nucleoside transport(GO:0015864)
0.0 0.1 GO:0045806 negative regulation of endocytosis(GO:0045806)
0.0 0.2 GO:0032964 collagen biosynthetic process(GO:0032964)
0.0 0.0 GO:0035511 oxidative DNA demethylation(GO:0035511)
0.0 0.0 GO:0061082 myeloid leukocyte cytokine production(GO:0061082)
0.0 0.2 GO:0048008 platelet-derived growth factor receptor signaling pathway(GO:0048008)
0.0 0.1 GO:0031529 ruffle organization(GO:0031529)
0.0 0.0 GO:0006930 substrate-dependent cell migration, cell extension(GO:0006930)
0.0 0.0 GO:0070296 sarcoplasmic reticulum calcium ion transport(GO:0070296)
0.0 0.1 GO:0046349 amino sugar biosynthetic process(GO:0046349)
0.0 0.1 GO:0006703 estrogen biosynthetic process(GO:0006703)
0.0 0.1 GO:0002566 somatic diversification of immune receptors via somatic mutation(GO:0002566) somatic hypermutation of immunoglobulin genes(GO:0016446)
0.0 0.3 GO:0010811 positive regulation of cell-substrate adhesion(GO:0010811)
0.0 0.0 GO:0015959 diadenosine polyphosphate metabolic process(GO:0015959)
0.0 0.0 GO:0048845 venous blood vessel morphogenesis(GO:0048845)
0.0 0.0 GO:0006290 pyrimidine dimer repair(GO:0006290)
0.0 0.0 GO:0045542 positive regulation of cholesterol biosynthetic process(GO:0045542)
0.0 0.1 GO:0032786 positive regulation of DNA-templated transcription, elongation(GO:0032786)
0.0 0.0 GO:0071425 hematopoietic stem cell proliferation(GO:0071425)
0.0 0.0 GO:0033599 regulation of mammary gland epithelial cell proliferation(GO:0033599)
0.0 0.1 GO:0006776 vitamin A metabolic process(GO:0006776)
0.0 0.0 GO:0032331 negative regulation of chondrocyte differentiation(GO:0032331)
0.0 0.0 GO:0030952 establishment or maintenance of cytoskeleton polarity(GO:0030952)
0.0 0.0 GO:0002281 macrophage activation involved in immune response(GO:0002281)
0.0 0.0 GO:0090175 Wnt signaling pathway, planar cell polarity pathway(GO:0060071) regulation of establishment of planar polarity(GO:0090175)
0.0 0.1 GO:0015074 DNA integration(GO:0015074)
0.0 0.1 GO:0007143 female meiotic division(GO:0007143)
0.0 0.0 GO:0048840 otolith development(GO:0048840)
0.0 0.0 GO:0019532 oxalate transport(GO:0019532)
0.0 0.0 GO:0051409 response to nitrosative stress(GO:0051409)
0.0 0.1 GO:0042167 porphyrin-containing compound catabolic process(GO:0006787) tetrapyrrole catabolic process(GO:0033015) heme catabolic process(GO:0042167) pigment catabolic process(GO:0046149)
0.0 0.0 GO:0010815 bradykinin catabolic process(GO:0010815)
0.0 0.0 GO:0021910 smoothened signaling pathway involved in ventral spinal cord patterning(GO:0021910)
0.0 0.0 GO:0006655 phosphatidylglycerol biosynthetic process(GO:0006655) cardiolipin metabolic process(GO:0032048) cardiolipin biosynthetic process(GO:0032049) phosphatidylglycerol metabolic process(GO:0046471)
0.0 0.0 GO:0010745 negative regulation of macrophage derived foam cell differentiation(GO:0010745)
0.0 0.0 GO:1901984 negative regulation of histone acetylation(GO:0035067) negative regulation of protein acetylation(GO:1901984) negative regulation of peptidyl-lysine acetylation(GO:2000757)
0.0 0.0 GO:0046606 negative regulation of centrosome duplication(GO:0010826) negative regulation of centrosome cycle(GO:0046606)
0.0 0.0 GO:0009191 nucleoside diphosphate catabolic process(GO:0009134) ribonucleoside diphosphate catabolic process(GO:0009191)
0.0 0.1 GO:0090114 vesicle targeting, rough ER to cis-Golgi(GO:0048207) COPII vesicle coating(GO:0048208) COPII-coated vesicle budding(GO:0090114)
0.0 0.0 GO:0048712 negative regulation of astrocyte differentiation(GO:0048712)
0.0 0.0 GO:0042640 anagen(GO:0042640)
0.0 0.1 GO:0006590 thyroid hormone generation(GO:0006590)
0.0 0.1 GO:0090103 cochlea morphogenesis(GO:0090103)
0.0 0.0 GO:0044256 multicellular organismal protein catabolic process(GO:0044254) protein digestion(GO:0044256) multicellular organismal macromolecule catabolic process(GO:0044266) multicellular organismal protein metabolic process(GO:0044268)
0.0 0.0 GO:0006534 cysteine metabolic process(GO:0006534)
0.0 0.0 GO:0002023 reduction of food intake in response to dietary excess(GO:0002023)
0.0 0.0 GO:0006435 threonyl-tRNA aminoacylation(GO:0006435)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0032449 CBM complex(GO:0032449)
0.1 0.1 GO:0071664 catenin-TCF7L2 complex(GO:0071664)
0.0 0.2 GO:0042825 TAP complex(GO:0042825)
0.0 0.3 GO:0098651 basement membrane collagen trimer(GO:0098651)
0.0 0.3 GO:0005614 interstitial matrix(GO:0005614)
0.0 0.2 GO:0002102 podosome(GO:0002102)
0.0 0.2 GO:0031232 extrinsic component of external side of plasma membrane(GO:0031232)
0.0 0.1 GO:0071942 XPC complex(GO:0071942)
0.0 0.1 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.0 0.2 GO:0005915 zonula adherens(GO:0005915)
0.0 0.1 GO:0030056 hemidesmosome(GO:0030056)
0.0 0.2 GO:0005916 fascia adherens(GO:0005916)
0.0 0.1 GO:0034363 intermediate-density lipoprotein particle(GO:0034363)
0.0 0.1 GO:0005588 collagen type V trimer(GO:0005588)
0.0 0.1 GO:0031265 CD95 death-inducing signaling complex(GO:0031265)
0.0 0.1 GO:0071062 alphav-beta3 integrin-vitronectin complex(GO:0071062)
0.0 0.1 GO:0098647 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.0 0.1 GO:0032059 bleb(GO:0032059)
0.0 0.1 GO:0030127 COPII vesicle coat(GO:0030127)
0.0 0.2 GO:0098644 complex of collagen trimers(GO:0098644)
0.0 0.1 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.0 0.1 GO:0072669 tRNA-splicing ligase complex(GO:0072669)
0.0 0.0 GO:0014704 intercalated disc(GO:0014704) cell-cell contact zone(GO:0044291)
0.0 0.2 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0 0.1 GO:0002178 palmitoyltransferase complex(GO:0002178) serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211)
0.0 0.1 GO:0034366 spherical high-density lipoprotein particle(GO:0034366)
0.0 0.3 GO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
0.0 0.1 GO:0005606 laminin-1 complex(GO:0005606)
0.0 0.2 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 0.1 GO:0045254 pyruvate dehydrogenase complex(GO:0045254)
0.0 0.1 GO:0031527 filopodium membrane(GO:0031527)
0.0 0.1 GO:0031430 M band(GO:0031430)
0.0 0.0 GO:0030934 anchoring collagen complex(GO:0030934)
0.0 0.4 GO:0001725 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.0 0.1 GO:0030128 AP-2 adaptor complex(GO:0030122) clathrin coat of endocytic vesicle(GO:0030128)
0.0 0.1 GO:0042587 glycogen granule(GO:0042587)
0.0 0.1 GO:0031512 motile primary cilium(GO:0031512)
0.0 1.1 GO:0070160 bicellular tight junction(GO:0005923) occluding junction(GO:0070160)
0.0 0.1 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.0 0.2 GO:0030315 T-tubule(GO:0030315)
0.0 0.1 GO:0008290 F-actin capping protein complex(GO:0008290)
0.0 0.2 GO:0005581 collagen trimer(GO:0005581)
0.0 0.1 GO:0036454 insulin-like growth factor binding protein complex(GO:0016942) growth factor complex(GO:0036454)
0.0 0.0 GO:0000176 nuclear exosome (RNase complex)(GO:0000176)
0.0 0.7 GO:0030426 growth cone(GO:0030426)
0.0 0.1 GO:0036126 outer dense fiber(GO:0001520) sperm flagellum(GO:0036126)
0.0 0.1 GO:0035253 ciliary rootlet(GO:0035253)
0.0 0.1 GO:0031233 intrinsic component of external side of plasma membrane(GO:0031233)
0.0 0.0 GO:0031371 ubiquitin conjugating enzyme complex(GO:0031371)
0.0 0.0 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.0 0.0 GO:0005641 nuclear envelope lumen(GO:0005641)
0.0 0.1 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.0 0.2 GO:0030057 desmosome(GO:0030057)
0.0 0.1 GO:0032838 cell projection cytoplasm(GO:0032838)
0.0 0.0 GO:0000124 SAGA complex(GO:0000124)
0.0 0.5 GO:0031012 extracellular matrix(GO:0031012)
0.0 0.2 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.0 2.9 GO:0005578 proteinaceous extracellular matrix(GO:0005578)
0.0 1.0 GO:0005925 focal adhesion(GO:0005925)
0.0 0.1 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.0 0.1 GO:0005847 mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.0 0.0 GO:0009331 glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.0 0.1 GO:0031332 RISC complex(GO:0016442) RNAi effector complex(GO:0031332)
0.0 0.0 GO:0005900 oncostatin-M receptor complex(GO:0005900)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0005010 insulin-like growth factor-activated receptor activity(GO:0005010)
0.1 0.3 GO:0050508 glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0050508)
0.1 0.5 GO:0017154 semaphorin receptor activity(GO:0017154)
0.1 0.3 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.1 0.3 GO:0004111 creatine kinase activity(GO:0004111)
0.1 0.3 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.1 0.3 GO:0004668 protein-arginine deiminase activity(GO:0004668)
0.1 0.2 GO:0043184 vascular endothelial growth factor receptor 2 binding(GO:0043184)
0.1 0.2 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.1 0.2 GO:0070324 thyroid hormone binding(GO:0070324)
0.1 0.2 GO:0046980 tapasin binding(GO:0046980)
0.1 0.2 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.1 0.4 GO:0001085 RNA polymerase II transcription factor binding(GO:0001085)
0.1 0.2 GO:0047623 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.1 0.2 GO:0042978 ornithine decarboxylase activator activity(GO:0042978)
0.0 0.2 GO:0016934 extracellular-glycine-gated ion channel activity(GO:0016933) extracellular-glycine-gated chloride channel activity(GO:0016934)
0.0 0.2 GO:0016416 carnitine O-palmitoyltransferase activity(GO:0004095) O-palmitoyltransferase activity(GO:0016416)
0.0 0.1 GO:0005172 vascular endothelial growth factor receptor binding(GO:0005172)
0.0 0.1 GO:0015204 urea transmembrane transporter activity(GO:0015204)
0.0 0.3 GO:0017166 vinculin binding(GO:0017166)
0.0 0.2 GO:0015016 [heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
0.0 0.1 GO:0005127 ciliary neurotrophic factor receptor binding(GO:0005127)
0.0 0.2 GO:0004656 procollagen-proline 4-dioxygenase activity(GO:0004656) peptidyl-proline 4-dioxygenase activity(GO:0031545)
0.0 0.0 GO:0004924 oncostatin-M receptor activity(GO:0004924)
0.0 0.1 GO:0005006 epidermal growth factor-activated receptor activity(GO:0005006)
0.0 0.1 GO:0004117 calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117)
0.0 0.1 GO:0005432 calcium:sodium antiporter activity(GO:0005432)
0.0 0.1 GO:0019211 phosphatase activator activity(GO:0019211)
0.0 0.2 GO:0005161 platelet-derived growth factor receptor binding(GO:0005161)
0.0 0.1 GO:0043125 ErbB-3 class receptor binding(GO:0043125)
0.0 0.1 GO:0008184 glycogen phosphorylase activity(GO:0008184)
0.0 0.1 GO:0005017 platelet-derived growth factor-activated receptor activity(GO:0005017)
0.0 0.1 GO:0043495 protein anchor(GO:0043495)
0.0 0.0 GO:0019237 centromeric DNA binding(GO:0019237)
0.0 0.1 GO:0050544 arachidonic acid binding(GO:0050544)
0.0 0.1 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
0.0 0.1 GO:0005346 purine ribonucleotide transmembrane transporter activity(GO:0005346)
0.0 0.1 GO:0042805 actinin binding(GO:0042805)
0.0 0.1 GO:0003701 obsolete RNA polymerase I transcription factor activity(GO:0003701)
0.0 0.2 GO:0042153 obsolete RPTP-like protein binding(GO:0042153)
0.0 0.1 GO:0003680 AT DNA binding(GO:0003680)
0.0 0.1 GO:0033130 acetylcholine receptor binding(GO:0033130)
0.0 0.1 GO:0031821 G-protein coupled serotonin receptor binding(GO:0031821)
0.0 0.2 GO:0070696 transmembrane receptor protein serine/threonine kinase binding(GO:0070696)
0.0 0.2 GO:0030492 hemoglobin binding(GO:0030492)
0.0 0.1 GO:0000293 ferric-chelate reductase activity(GO:0000293)
0.0 0.1 GO:0016941 natriuretic peptide receptor activity(GO:0016941)
0.0 0.1 GO:0004616 phosphogluconate dehydrogenase (decarboxylating) activity(GO:0004616)
0.0 0.1 GO:0070644 vitamin D response element binding(GO:0070644)
0.0 0.0 GO:1901567 icosanoid binding(GO:0050542) fatty acid derivative binding(GO:1901567)
0.0 0.1 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.0 0.1 GO:0045499 chemorepellent activity(GO:0045499)
0.0 0.0 GO:0016406 carnitine O-acyltransferase activity(GO:0016406)
0.0 0.1 GO:0050501 hyaluronan synthase activity(GO:0050501)
0.0 0.3 GO:0005523 tropomyosin binding(GO:0005523)
0.0 0.0 GO:0016509 long-chain-3-hydroxyacyl-CoA dehydrogenase activity(GO:0016509)
0.0 0.1 GO:0001758 retinal dehydrogenase activity(GO:0001758)
0.0 0.6 GO:0005158 insulin receptor binding(GO:0005158)
0.0 0.2 GO:0042171 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841) lysophosphatidic acid acyltransferase activity(GO:0042171) lysophospholipid acyltransferase activity(GO:0071617)
0.0 0.2 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.0 0.1 GO:0060230 lipoprotein lipase activator activity(GO:0060230)
0.0 0.0 GO:0070273 phosphatidylinositol-4-phosphate binding(GO:0070273)
0.0 0.1 GO:0005294 neutral L-amino acid secondary active transmembrane transporter activity(GO:0005294)
0.0 0.1 GO:0004307 ethanolaminephosphotransferase activity(GO:0004307)
0.0 0.1 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.0 0.1 GO:0070653 high-density lipoprotein particle receptor binding(GO:0070653)
0.0 0.0 GO:0004645 phosphorylase activity(GO:0004645)
0.0 0.0 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 0.2 GO:0015245 fatty acid transporter activity(GO:0015245)
0.0 0.3 GO:0016641 oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor(GO:0016641)
0.0 0.0 GO:0005176 ErbB-2 class receptor binding(GO:0005176)
0.0 0.1 GO:0004937 alpha1-adrenergic receptor activity(GO:0004937)
0.0 0.1 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.0 0.1 GO:0031995 insulin-like growth factor II binding(GO:0031995)
0.0 0.1 GO:0004862 cAMP-dependent protein kinase inhibitor activity(GO:0004862)
0.0 0.1 GO:0031544 procollagen-proline 3-dioxygenase activity(GO:0019797) peptidyl-proline 3-dioxygenase activity(GO:0031544)
0.0 0.1 GO:0005110 frizzled-2 binding(GO:0005110)
0.0 0.1 GO:0005143 interleukin-12 receptor binding(GO:0005143)
0.0 0.1 GO:0004630 phospholipase D activity(GO:0004630)
0.0 0.1 GO:0004075 biotin carboxylase activity(GO:0004075)
0.0 0.1 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
0.0 0.1 GO:0004800 thyroxine 5'-deiodinase activity(GO:0004800)
0.0 0.0 GO:0008035 high-density lipoprotein particle binding(GO:0008035)
0.0 0.1 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.0 0.1 GO:0003696 satellite DNA binding(GO:0003696)
0.0 0.1 GO:0005030 neurotrophin receptor activity(GO:0005030)
0.0 0.1 GO:0015106 bicarbonate transmembrane transporter activity(GO:0015106)
0.0 0.1 GO:0030371 translation repressor activity(GO:0030371)
0.0 0.1 GO:0008046 axon guidance receptor activity(GO:0008046)
0.0 0.1 GO:0004523 RNA-DNA hybrid ribonuclease activity(GO:0004523)
0.0 0.1 GO:0004965 G-protein coupled GABA receptor activity(GO:0004965)
0.0 0.0 GO:0000404 heteroduplex DNA loop binding(GO:0000404)
0.0 0.0 GO:0050693 LBD domain binding(GO:0050693)
0.0 0.1 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity(GO:0004694)
0.0 0.1 GO:0016713 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen(GO:0016713)
0.0 0.1 GO:0016717 oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water(GO:0016717)
0.0 0.0 GO:0016885 ligase activity, forming carbon-carbon bonds(GO:0016885)
0.0 0.0 GO:0035673 oligopeptide transmembrane transporter activity(GO:0035673)
0.0 0.1 GO:0017110 nucleoside-diphosphatase activity(GO:0017110)
0.0 0.1 GO:0030506 ankyrin binding(GO:0030506)
0.0 0.1 GO:0015385 sodium:proton antiporter activity(GO:0015385)
0.0 0.1 GO:0004985 opioid receptor activity(GO:0004985)
0.0 0.0 GO:0032554 purine deoxyribonucleotide binding(GO:0032554) adenyl deoxyribonucleotide binding(GO:0032558)
0.0 0.2 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.0 0.0 GO:0042808 obsolete neuronal Cdc2-like kinase binding(GO:0042808)
0.0 0.0 GO:0097506 uracil DNA N-glycosylase activity(GO:0004844) deaminated base DNA N-glycosylase activity(GO:0097506)
0.0 0.0 GO:0032137 guanine/thymine mispair binding(GO:0032137)
0.0 0.1 GO:0070053 thrombospondin receptor activity(GO:0070053)
0.0 0.0 GO:0036041 long-chain fatty acid binding(GO:0036041)
0.0 0.1 GO:0051019 mitogen-activated protein kinase binding(GO:0051019)
0.0 0.0 GO:0070735 protein-glycine ligase activity(GO:0070735)
0.0 0.1 GO:0050998 nitric-oxide synthase binding(GO:0050998)
0.0 0.0 GO:0008330 protein tyrosine/threonine phosphatase activity(GO:0008330)
0.0 0.0 GO:0005152 interleukin-1 receptor antagonist activity(GO:0005152)
0.0 0.0 GO:0001515 opioid peptide activity(GO:0001515)
0.0 0.1 GO:0004385 guanylate kinase activity(GO:0004385)
0.0 0.1 GO:0051010 microtubule plus-end binding(GO:0051010)
0.0 0.0 GO:0043559 insulin binding(GO:0043559)
0.0 0.0 GO:0030151 molybdenum ion binding(GO:0030151)
0.0 0.2 GO:0042301 phosphate ion binding(GO:0042301)
0.0 0.1 GO:0034185 apolipoprotein binding(GO:0034185)
0.0 0.0 GO:0002162 dystroglycan binding(GO:0002162)
0.0 0.1 GO:0015368 calcium:cation antiporter activity(GO:0015368) potassium ion antiporter activity(GO:0022821)
0.0 0.0 GO:0030023 extracellular matrix constituent conferring elasticity(GO:0030023) structural molecule activity conferring elasticity(GO:0097493)
0.0 0.0 GO:0035514 DNA demethylase activity(GO:0035514) DNA-N1-methyladenine dioxygenase activity(GO:0043734)
0.0 0.0 GO:0070052 collagen V binding(GO:0070052)
0.0 0.1 GO:0017049 GTP-Rho binding(GO:0017049)
0.0 0.0 GO:0070097 delta-catenin binding(GO:0070097)
0.0 0.0 GO:0048495 Roundabout binding(GO:0048495)
0.0 0.1 GO:0030274 LIM domain binding(GO:0030274)
0.0 0.1 GO:0051787 misfolded protein binding(GO:0051787)
0.0 0.0 GO:0016802 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.0 0.0 GO:0033829 O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.0 0.0 GO:0031994 insulin-like growth factor I binding(GO:0031994)
0.0 0.1 GO:0005149 interleukin-1 receptor binding(GO:0005149)
0.0 0.0 GO:0008061 chitin binding(GO:0008061)
0.0 0.0 GO:0016901 oxidoreductase activity, acting on the CH-OH group of donors, quinone or similar compound as acceptor(GO:0016901)
0.0 0.1 GO:0015174 basic amino acid transmembrane transporter activity(GO:0015174)
0.0 0.0 GO:0070643 vitamin D3 25-hydroxylase activity(GO:0030343) vitamin D 25-hydroxylase activity(GO:0070643)
0.0 0.0 GO:0004594 pantothenate kinase activity(GO:0004594)
0.0 0.1 GO:0016653 oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor(GO:0016653)
0.0 0.0 GO:0019834 phospholipase A2 inhibitor activity(GO:0019834)
0.0 0.1 GO:0016813 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
0.0 0.1 GO:0030507 spectrin binding(GO:0030507)
0.0 0.3 GO:0005518 collagen binding(GO:0005518)
0.0 0.0 GO:0004739 pyruvate dehydrogenase activity(GO:0004738) pyruvate dehydrogenase (acetyl-transferring) activity(GO:0004739)
0.0 0.1 GO:0030250 cyclase activator activity(GO:0010853) guanylate cyclase activator activity(GO:0030250)
0.0 0.0 GO:0005138 interleukin-6 receptor binding(GO:0005138)
0.0 0.0 GO:0099602 acetylcholine receptor regulator activity(GO:0030548) neurotransmitter receptor regulator activity(GO:0099602)
0.0 0.2 GO:0050840 extracellular matrix binding(GO:0050840)
0.0 0.1 GO:0016847 1-aminocyclopropane-1-carboxylate synthase activity(GO:0016847)
0.0 0.0 GO:0004758 serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
0.0 0.1 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.0 0.0 GO:0015142 citrate transmembrane transporter activity(GO:0015137) tricarboxylic acid transmembrane transporter activity(GO:0015142)
0.0 0.1 GO:0008198 ferrous iron binding(GO:0008198)
0.0 0.7 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 0.1 GO:0005123 death receptor binding(GO:0005123)
0.0 0.0 GO:0008107 galactoside 2-alpha-L-fucosyltransferase activity(GO:0008107) alpha-(1,2)-fucosyltransferase activity(GO:0031127)
0.0 0.1 GO:0015280 ligand-gated sodium channel activity(GO:0015280)
0.0 0.0 GO:0015194 L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.0 0.1 GO:0008159 obsolete positive transcription elongation factor activity(GO:0008159)
0.0 0.1 GO:0055102 lipase inhibitor activity(GO:0055102)
0.0 0.0 GO:0001849 complement component C1q binding(GO:0001849)
0.0 0.0 GO:0004829 threonine-tRNA ligase activity(GO:0004829)
0.0 0.0 GO:0019855 calcium channel inhibitor activity(GO:0019855)
0.0 0.1 GO:0004945 angiotensin receptor activity(GO:0001595) angiotensin type II receptor activity(GO:0004945)
0.0 0.1 GO:0001228 transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0000982) transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077) transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.0 0.1 GO:0004551 nucleotide diphosphatase activity(GO:0004551)
0.0 0.1 GO:0015166 polyol transmembrane transporter activity(GO:0015166)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.5 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.0 1.0 NABA COLLAGENS Genes encoding collagen proteins
0.0 0.0 PID GLYPICAN 1PATHWAY Glypican 1 network
0.0 0.7 PID UPA UPAR PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.0 0.2 PID S1P S1P1 PATHWAY S1P1 pathway
0.0 0.0 PID PI3KCI AKT PATHWAY Class I PI3K signaling events mediated by Akt
0.0 0.0 PID IGF1 PATHWAY IGF1 pathway
0.0 0.2 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
0.0 0.3 NABA BASEMENT MEMBRANES Genes encoding structural components of basement membranes
0.0 0.0 PID NFAT 3PATHWAY Role of Calcineurin-dependent NFAT signaling in lymphocytes
0.0 0.3 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.0 0.3 PID INTEGRIN1 PATHWAY Beta1 integrin cell surface interactions
0.0 0.2 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.0 0.4 PID ECADHERIN STABILIZATION PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.0 0.0 PID INSULIN PATHWAY Insulin Pathway
0.0 0.4 PID PI3K PLC TRK PATHWAY Trk receptor signaling mediated by PI3K and PLC-gamma
0.0 0.2 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.8 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.0 0.3 REACTOME VITAMIN B5 PANTOTHENATE METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
0.0 0.5 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.0 0.2 REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the late endosome membrane
0.0 0.4 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.0 1.2 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.0 0.0 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.0 0.3 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.0 0.2 REACTOME DCC MEDIATED ATTRACTIVE SIGNALING Genes involved in DCC mediated attractive signaling
0.0 0.6 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.0 0.2 REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.0 0.0 REACTOME G ALPHA Z SIGNALLING EVENTS Genes involved in G alpha (z) signalling events
0.0 0.2 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.0 0.2 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.0 0.2 REACTOME ADENYLATE CYCLASE INHIBITORY PATHWAY Genes involved in Adenylate cyclase inhibitory pathway
0.0 0.2 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport
0.0 0.1 REACTOME PURINE CATABOLISM Genes involved in Purine catabolism
0.0 0.1 REACTOME REGULATED PROTEOLYSIS OF P75NTR Genes involved in Regulated proteolysis of p75NTR
0.0 0.1 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.0 0.1 REACTOME NFKB IS ACTIVATED AND SIGNALS SURVIVAL Genes involved in NF-kB is activated and signals survival
0.0 0.3 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor
0.0 0.0 REACTOME SCF BETA TRCP MEDIATED DEGRADATION OF EMI1 Genes involved in SCF-beta-TrCP mediated degradation of Emi1
0.0 0.1 REACTOME SIGNALING BY FGFR3 MUTANTS Genes involved in Signaling by FGFR3 mutants
0.0 0.4 REACTOME MYOGENESIS Genes involved in Myogenesis
0.0 0.3 REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.0 0.1 REACTOME ENDOGENOUS STEROLS Genes involved in Endogenous sterols
0.0 0.0 REACTOME HYALURONAN METABOLISM Genes involved in Hyaluronan metabolism
0.0 0.2 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions