Project

ENCODE: H3K4me1 ChIP-Seq of primary human cells

Navigation

Downloads

Results for PPARG

Z-value: 1.79

Motif logo

Transcription factors associated with PPARG

Gene Symbol	Gene ID	Gene Info
PPARG Ensembl NCBI GeneCards UniProt	ENSG00000132170.15	peroxisome proliferator activated receptor gamma

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE	Gene	Distance	Association probability	Pearson corr. coef.	P-value	Plot
chr3_12395833_12395984	PPARG	2937	0.349675	-0.93	3.1e-04	Click!
chr3_12266121_12266272	PPARG	62671	0.122427	-0.82	6.6e-03	Click!
chr3_12377941_12378223	PPARG	14889	0.256190	0.74	2.4e-02	Click!
chr3_12422682_12422833	PPARG	29786	0.196860	0.73	2.5e-02	Click!
chr3_12276997_12277148	PPARG	51795	0.150660	-0.72	2.8e-02	Click!

Activity of the PPARG motif across conditions

Conditions sorted by the z-value of the PPARG motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE)	Target Score	Top associated gene	Gene Info	Distance of CRE to TSS	CRE/Gene association probability
chr7_99819712_99820188	1.09	ENSG00000222482	.	2207	0.15
chr3_187696515_187696882	1.07	LPP	LIM domain containing preferred translocation partner in lipoma	174374	0.03
chr7_148981019_148981379	0.86	ZNF783	zinc finger family member 783	1203	0.36
chr7_2739468_2739742	0.75	AMZ1	archaelysin family metallopeptidase 1	11769	0.21
chr1_202132763_202133787	0.72	PTPN7	protein tyrosine phosphatase, non-receptor type 7	2559	0.21
chr11_65408846_65409255	0.70	SIPA1	signal-induced proliferation-associated 1	751	0.41
chr19_49838163_49838543	0.66	CD37	CD37 molecule	300	0.78
chr11_6424420_6425308	0.66	APBB1	amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65)	1030	0.44
chr9_137367972_137368123	0.66	RXRA	retinoid X receptor, alpha	69619	0.11
chr16_57168390_57168643	0.61	CPNE2	copine II	15405	0.14
chr14_98676295_98676520	0.58	ENSG00000222066	.	121680	0.06
chr14_100546662_100546850	0.58	CTD-2376I20.1		5541	0.16
chr16_79313034_79313388	0.57	ENSG00000222244	.	14860	0.29
chr11_12378207_12378574	0.57	ENSG00000264283	.	12076	0.19
chr16_88545798_88545998	0.56	ENSG00000263456	.	10572	0.17
chr11_121351250_121351763	0.56	RP11-730K11.1		27784	0.21
chr12_133064825_133065258	0.55	FBRSL1	fibrosin-like 1	1096	0.54
chr16_50308946_50309418	0.55	ADCY7	adenylate cyclase 7	1118	0.53
chr12_113527618_113527818	0.54	DTX1	deltex homolog 1 (Drosophila)	32223	0.11
chr21_32549988_32550321	0.54	TIAM1	T-cell lymphoma invasion and metastasis 1	47615	0.18
chr11_73716797_73717380	0.53	UCP3	uncoupling protein 3 (mitochondrial, proton carrier)	1261	0.4
chr3_33095798_33096165	0.53	GLB1	galactosidase, beta 1	42303	0.12
chr3_33094206_33094581	0.53	GLB1	galactosidase, beta 1	43891	0.12
chrX_152603368_152603519	0.52	ZNF275	zinc finger protein 275	3830	0.2
chr10_15227195_15227346	0.52	NMT2	N-myristoyltransferase 2	16578	0.2
chr10_6571440_6571602	0.52	PRKCQ	protein kinase C, theta	50680	0.18
chr1_206755327_206755741	0.52	RASSF5	Ras association (RalGDS/AF-6) domain family member 5	25041	0.13
chr22_45016760_45017091	0.51	PRR5	proline rich 5 (renal)	47668	0.15
chr3_14924290_14924594	0.51	FGD5	FYVE, RhoGEF and PH domain containing 5	61503	0.1
chr8_81289205_81289813	0.51	ENSG00000252884	.	28242	0.19
chr17_38762219_38762396	0.51	SMARCE1	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 1	26235	0.12
chr17_72751609_72751889	0.51	SLC9A3R1	solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 1	6393	0.1
chr6_167533760_167534243	0.50	CCR6	chemokine (C-C motif) receptor 6	2256	0.3
chr3_177360373_177360796	0.50	ENSG00000200288	.	18387	0.29
chr20_57723964_57724434	0.50	ZNF831	zinc finger protein 831	41876	0.16
chr17_76128893_76129294	0.50	TMC6	transmembrane channel-like 6	605	0.58
chr2_122496335_122496524	0.50	TSN	translin	1750	0.3
chr11_1781297_1781822	0.49	AC068580.6		19	0.92
chr20_39775264_39775450	0.49	RP1-1J6.2		8714	0.2
chr14_106453805_106454306	0.49	IGHV1-2	immunoglobulin heavy variable 1-2	885	0.24
chr19_17112962_17113366	0.49	CTD-2528A14.1		6835	0.15
chr5_133467358_133467605	0.49	TCF7	transcription factor 7 (T-cell specific, HMG-box)	8172	0.21
chr20_31123380_31123862	0.49	C20orf112	chromosome 20 open reading frame 112	579	0.74
chr7_2739159_2739434	0.48	AMZ1	archaelysin family metallopeptidase 1	11460	0.21
chr3_15503071_15503367	0.48	EAF1-AS1	EAF1 antisense RNA 1	10110	0.12
chr19_49902085_49902258	0.48	CCDC155	coiled-coil domain containing 155	4371	0.08
chr14_61850578_61851088	0.48	PRKCH	protein kinase C, eta	6579	0.26
chr7_8171333_8171763	0.48	AC006042.6		17893	0.2
chr2_113944916_113945243	0.47	PSD4	pleckstrin and Sec7 domain containing 4	8778	0.14
chr11_67173408_67173659	0.47	TBC1D10C	TBC1 domain family, member 10C	1873	0.13
chr5_35852211_35852414	0.47	IL7R	interleukin 7 receptor	485	0.82
chr10_3462118_3462297	0.47	PITRM1	pitrilysin metallopeptidase 1	247204	0.02
chr10_29969072_29969239	0.47	ENSG00000222092	.	31689	0.18
chr19_51627416_51627752	0.47	SIGLEC9	sialic acid binding Ig-like lectin 9	581	0.56
chr5_156644403_156644620	0.47	CTB-4E7.1		6879	0.14
chr1_160535323_160535488	0.47	CD84	CD84 molecule	13858	0.13
chr22_18258720_18259014	0.46	BID	BH3 interacting domain death agonist	1436	0.41
chr3_46390356_46390605	0.46	CCR2	chemokine (C-C motif) receptor 2	4745	0.2
chr22_37543853_37544124	0.46	IL2RB	interleukin 2 receptor, beta	2042	0.21
chr1_25252459_25252702	0.46	RUNX3	runt-related transcription factor 3	3032	0.3
chr5_1313612_1313923	0.46	ENSG00000263670	.	4275	0.2
chr12_121473450_121473650	0.46	OASL	2'-5'-oligoadenylate synthetase-like	3200	0.19
chr4_40218742_40218915	0.45	RHOH	ras homolog family member H	16864	0.21
chr22_27040168_27040347	0.45	CRYBA4	crystallin, beta A4	22329	0.17
chr10_73863981_73864132	0.45	SPOCK2	sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2	15266	0.2
chr6_33873520_33874114	0.45	ENSG00000221697	.	94011	0.06
chr20_43277539_43277694	0.45	ADA	adenosine deaminase	2716	0.2
chr21_46338509_46338732	0.44	ITGB2	integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)	2150	0.17
chr19_16467370_16467664	0.44	EPS15L1	epidermal growth factor receptor pathway substrate 15-like 1	5247	0.16
chr17_999891_1000162	0.44	ABR	active BCR-related	12314	0.2
chr6_5522387_5522696	0.44	RP1-232P20.1		64233	0.14
chr1_207090489_207090800	0.44	FAIM3	Fas apoptotic inhibitory molecule 3	4568	0.17
chr14_101106211_101106459	0.44	CTD-2644I21.1		50672	0.08
chr7_149565914_149566574	0.44	ATP6V0E2	ATPase, H+ transporting V0 subunit e2	3813	0.19
chr5_175956521_175957004	0.44	RNF44	ring finger protein 44	884	0.47
chr3_46416206_46416357	0.44	CCR5	chemokine (C-C motif) receptor 5 (gene/pseudogene)	2120	0.26
chr8_134067708_134067917	0.43	SLA	Src-like-adaptor	4791	0.28
chr1_154238433_154238584	0.43	ENSG00000201129	.	6305	0.08
chr10_4170376_4170710	0.43	KLF6	Kruppel-like factor 6	343070	0.01
chr7_148325963_148326351	0.43	C7orf33	chromosome 7 open reading frame 33	38500	0.16
chr5_110564408_110564849	0.43	CAMK4	calcium/calmodulin-dependent protein kinase IV	4844	0.26
chr7_38407986_38408314	0.43	AMPH	amphiphysin	94563	0.09
chr16_30392632_30392982	0.43	SEPT1	septin 1	945	0.31
chr14_22974081_22974308	0.43	TRAJ51	T cell receptor alpha joining 51 (pseudogene)	18023	0.09
chr9_132345350_132345729	0.43	RP11-492E3.2		7851	0.14
chr9_130623880_130624317	0.43	ENG	endoglin	7063	0.08
chr9_95834544_95834805	0.42	SUSD3	sushi domain containing 3	3292	0.21
chr1_158899632_158899783	0.42	PYHIN1	pyrin and HIN domain family, member 1	879	0.64
chr4_1237782_1238175	0.42	CTBP1	C-terminal binding protein 1	2267	0.22
chr1_25248232_25248398	0.42	RUNX3	runt-related transcription factor 3	7297	0.24
chr17_47814433_47814907	0.42	FAM117A	family with sequence similarity 117, member A	12781	0.14
chr3_46005175_46005371	0.42	FYCO1	FYVE and coiled-coil domain containing 1	5120	0.19
chr14_91858369_91858695	0.42	CCDC88C	coiled-coil domain containing 88C	25158	0.2
chr15_32651213_32651761	0.42	ENSG00000221444	.	34186	0.1
chr2_235334226_235334544	0.42	ARL4C	ADP-ribosylation factor-like 4C	70859	0.14
chr8_125575470_125576116	0.42	MTSS1	metastasis suppressor 1	2175	0.26
chr22_23268788_23268939	0.42	IGLJ7	immunoglobulin lambda joining 7	5301	0.07
chr16_57163028_57163387	0.42	CPNE2	copine II	10096	0.15
chr1_207633000_207633151	0.42	CR2	complement component (3d/Epstein Barr virus) receptor 2	5365	0.23
chr17_39496825_39497026	0.42	KRT33A	keratin 33A	10139	0.08
chr2_102984737_102985012	0.41	IL18R1	interleukin 18 receptor 1	5753	0.19
chr8_125574992_125575143	0.41	MTSS1	metastasis suppressor 1	2901	0.21
chr19_16228666_16229162	0.41	RAB8A	RAB8A, member RAS oncogene family	6207	0.14
chr3_46411260_46411477	0.41	CCR5	chemokine (C-C motif) receptor 5 (gene/pseudogene)	265	0.9
chr2_28572176_28572390	0.41	AC093690.1		38957	0.13
chr1_9778118_9778444	0.41	PIK3CD	phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta	154	0.95
chr14_22565547_22565859	0.41	ENSG00000238634	.	45184	0.18
chr20_2723372_2723744	0.41	EBF4	early B-cell factor 4	36671	0.09
chr2_241503761_241504027	0.40	RNPEPL1	arginyl aminopeptidase (aminopeptidase B)-like 1	1327	0.3
chr16_68403491_68403775	0.40	SMPD3	sphingomyelin phosphodiesterase 3, neutral membrane (neutral sphingomyelinase II)	1275	0.35
chr17_37252182_37252943	0.40	PLXDC1	plexin domain containing 1	11178	0.15
chr14_21136496_21136717	0.40	ENSG00000199461	.	10964	0.09
chr6_160436305_160436759	0.40	AIRN	antisense of IGF2R non-protein coding RNA	7836	0.24
chr1_59407152_59407509	0.40	JUN	jun proto-oncogene	157545	0.04
chr17_81146535_81146986	0.40	METRNL	meteorin, glial cell differentiation regulator-like	94766	0.08
chr9_134143505_134143979	0.40	FAM78A	family with sequence similarity 78, member A	2138	0.29
chr4_40305683_40306008	0.40	CHRNA9	cholinergic receptor, nicotinic, alpha 9 (neuronal)	31501	0.18
chr4_40219694_40220159	0.40	RHOH	ras homolog family member H	17962	0.21
chr1_25253582_25253853	0.40	RUNX3	runt-related transcription factor 3	1895	0.39
chr6_112114827_112115099	0.39	FYN	FYN oncogene related to SRC, FGR, YES	126	0.98
chr1_776644_776929	0.39	RP11-206L10.8		31245	0.11
chr6_159519924_159520304	0.39	TAGAP	T-cell activation RhoGTPase activating protein	53930	0.11
chr19_42377110_42377408	0.39	CD79A	CD79a molecule, immunoglobulin-associated alpha	3931	0.13
chr17_46498324_46498623	0.39	SKAP1	src kinase associated phosphoprotein 1	9079	0.14
chr16_89762947_89763492	0.39	SPATA2L	spermatogenesis associated 2-like	4829	0.1
chr11_46352086_46352730	0.39	DGKZ	diacylglycerol kinase, zeta	2047	0.27
chr19_13213848_13214497	0.39	LYL1	lymphoblastic leukemia derived sequence 1	197	0.89
chr7_150359146_150359387	0.39	GIMAP2	GTPase, IMAP family member 2	23522	0.15
chr22_36684429_36684580	0.39	ENSG00000266345	.	27742	0.14
chr1_27165220_27165588	0.39	ZDHHC18	zinc finger, DHHC-type containing 18	6893	0.12
chr14_99450232_99450383	0.39	AL162151.4		174446	0.03
chr2_197048030_197048186	0.39	STK17B	serine/threonine kinase 17b	6881	0.2
chr1_228072467_228072618	0.39	ENSG00000264483	.	56842	0.1
chr2_74248551_74248821	0.38	TET3	tet methylcytosine dioxygenase 3	18846	0.16
chr17_35085631_35085782	0.38	MRM1	mitochondrial rRNA methyltransferase 1 homolog (S. cerevisiae)	127315	0.04
chr10_26768891_26769074	0.38	ENSG00000199733	.	29536	0.21
chr15_70550046_70550380	0.38	ENSG00000200216	.	64638	0.14
chr9_4596090_4596285	0.38	SLC1A1	solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1	23852	0.19
chrX_128904932_128905357	0.38	SASH3	SAM and SH3 domain containing 3	8816	0.2
chr1_54946013_54946309	0.38	ENSG00000265404	.	24180	0.16
chr11_119235370_119235524	0.38	USP2	ubiquitin specific peptidase 2	530	0.59
chr16_31707620_31707947	0.38	CLUHP3	clustered mitochondria (cluA/CLU1) homolog pseudogene 3	6706	0.17
chr3_68135261_68135467	0.38	FAM19A1	family with sequence similarity 19 (chemokine (C-C motif)-like), member A1	79991	0.12
chr6_149381041_149381264	0.38	RP11-162J8.3		27443	0.22
chr20_25022537_25022783	0.38	ACSS1	acyl-CoA synthetase short-chain family member 1	9321	0.2
chr11_60877401_60877552	0.38	CD5	CD5 molecule	7495	0.18
chr2_47173162_47173468	0.38	MCFD2	multiple coagulation factor deficiency 2	4321	0.17
chr14_22947374_22947525	0.38	TRAJ60	T cell receptor alpha joining 60 (pseudogene)	2153	0.16
chr2_74258310_74258513	0.38	TET3	tet methylcytosine dioxygenase 3	15039	0.17
chr2_233950353_233950744	0.38	INPP5D	inositol polyphosphate-5-phosphatase, 145kDa	25359	0.17
chr18_29563540_29563829	0.38	RNF125	ring finger protein 125, E3 ubiquitin protein ligase	34651	0.11
chr6_35279762_35280244	0.37	DEF6	differentially expressed in FDCP 6 homolog (mouse)	2488	0.27
chr2_68961132_68961308	0.37	ARHGAP25	Rho GTPase activating protein 25	693	0.77
chr20_57758094_57758324	0.37	ZNF831	zinc finger protein 831	7866	0.26
chr10_71318212_71318363	0.37	NEUROG3	neurogenin 3	14707	0.18
chrX_153582032_153582208	0.37	FLNA	filamin A, alpha	583	0.57
chr1_11802035_11802206	0.37	AGTRAP	angiotensin II receptor-associated protein	5888	0.13
chr16_3857767_3857985	0.37	CREBBP	CREB binding protein	27008	0.19
chr12_674006_674157	0.37	RP5-1154L15.2		21571	0.13
chr16_57021435_57021712	0.37	NLRC5	NLR family, CARD domain containing 5	1837	0.25
chr14_98637898_98638078	0.37	ENSG00000222066	.	160099	0.04
chr1_20015357_20015517	0.37	HTR6	5-hydroxytryptamine (serotonin) receptor 6, G protein-coupled	23657	0.16
chr12_40023753_40023976	0.37	C12orf40	chromosome 12 open reading frame 40	3879	0.28
chr10_121297891_121298084	0.37	RGS10	regulator of G-protein signaling 10	1942	0.4
chr18_2967412_2967563	0.37	RP11-737O24.1		471	0.77
chr9_140347294_140347548	0.37	NSMF	NMDA receptor synaptonuclear signaling and neuronal migration factor	1523	0.27
chr18_68307691_68307842	0.37	GTSCR1	Gilles de la Tourette syndrome chromosome region, candidate 1	10181	0.31
chr3_56952065_56952464	0.37	ARHGEF3	Rho guanine nucleotide exchange factor (GEF) 3	1765	0.42
chr10_89953557_89953785	0.37	ENSG00000200891	.	199219	0.03
chr9_70938018_70938169	0.37	FOXD4L3	forkhead box D4-like 3	20817	0.15
chr9_35910713_35911016	0.37	HRCT1	histidine rich carboxyl terminus 1	4675	0.15
chr2_106478965_106479116	0.37	AC009505.2		5407	0.26
chr10_6079510_6080013	0.36	IL2RA	interleukin 2 receptor, alpha	11797	0.14
chr9_96030770_96030921	0.36	WNK2	WNK lysine deficient protein kinase 2	4615	0.26
chr1_27160442_27160760	0.36	ZDHHC18	zinc finger, DHHC-type containing 18	2090	0.2
chr10_43790753_43790904	0.36	RASGEF1A	RasGEF domain family, member 1A	28461	0.17
chr10_9137729_9137996	0.36	ENSG00000212505	.	439068	0.01
chr16_89041472_89041726	0.36	CBFA2T3	core-binding factor, runt domain, alpha subunit 2; translocated to, 3	1802	0.3
chr12_3857026_3857275	0.36	EFCAB4B	EF-hand calcium binding domain 4B	5113	0.26
chr17_9372400_9372551	0.36	RP11-565F19.4		4416	0.22
chr11_722284_722581	0.36	AP006621.9		4615	0.09
chr1_27072713_27073114	0.36	ARID1A	AT rich interactive domain 1A (SWI-like)	17042	0.12
chr1_111179224_111179419	0.36	KCNA2	potassium voltage-gated channel, shaker-related subfamily, member 2	5225	0.2
chr11_4113400_4113717	0.36	RRM1	ribonucleotide reductase M1	2481	0.29
chr4_2817440_2817610	0.36	SH3BP2	SH3-domain binding protein 2	2387	0.3
chr11_73715681_73716026	0.36	UCP3	uncoupling protein 3 (mitochondrial, proton carrier)	2496	0.23
chr10_51503497_51503779	0.36	AGAP7	ArfGAP with GTPase domain, ankyrin repeat and PH domain 7	17311	0.19
chr1_247570539_247571127	0.36	NLRP3	NLR family, pyrin domain containing 3	8625	0.18
chr1_169670629_169671082	0.36	SELL	selectin L	9984	0.2
chr7_151125685_151126226	0.36	RP4-555L14.4		1186	0.33
chr19_4088417_4088592	0.36	MAP2K2	mitogen-activated protein kinase kinase 2	12541	0.11
chr20_31169576_31169970	0.36	RP11-410N8.1		8	0.97
chr4_2365742_2365893	0.36	ZFYVE28	zinc finger, FYVE domain containing 28	714	0.67
chr3_43386732_43386964	0.36	RP11-188P20.3		2287	0.28
chr1_1073051_1073561	0.36	C1orf159	chromosome 1 open reading frame 159	21565	0.08
chr3_128736783_128736934	0.36	EFCC1	EF-hand and coiled-coil domain containing 1	16386	0.13
chr15_81608011_81608276	0.36	STARD5	StAR-related lipid transfer (START) domain containing 5	8323	0.18
chr14_23011658_23011809	0.35	TRAJ15	T cell receptor alpha joining 15	13153	0.1
chr14_61903705_61903865	0.35	PRKCH	protein kinase C, eta	5491	0.27
chr19_8774866_8775027	0.35	ACTL9	actin-like 9	34226	0.15

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of PPARG

View svg image
View png image

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	0.6	GO:0035405	histone-threonine phosphorylation(GO:0035405)
0.2	1.2	GO:0070670	response to interleukin-4(GO:0070670)
0.2	0.6	GO:0045343	MHC class I biosynthetic process(GO:0045341) regulation of MHC class I biosynthetic process(GO:0045343)
0.2	0.6	GO:0031580	membrane raft polarization(GO:0001766) membrane raft distribution(GO:0031580)
0.2	0.2	GO:0034112	positive regulation of homotypic cell-cell adhesion(GO:0034112)
0.2	0.5	GO:0006154	adenosine catabolic process(GO:0006154)
0.2	0.5	GO:0030854	positive regulation of granulocyte differentiation(GO:0030854)
0.2	0.3	GO:0030223	neutrophil differentiation(GO:0030223)
0.2	0.6	GO:0001911	negative regulation of leukocyte mediated cytotoxicity(GO:0001911)
0.1	0.4	GO:0030186	melatonin metabolic process(GO:0030186) melatonin biosynthetic process(GO:0030187)
0.1	0.1	GO:0048537	mucosal-associated lymphoid tissue development(GO:0048537)
0.1	0.4	GO:0061526	acetylcholine secretion, neurotransmission(GO:0014055) regulation of acetylcholine secretion, neurotransmission(GO:0014056) acetylcholine secretion(GO:0061526)
0.1	0.4	GO:0042091	interleukin-10 biosynthetic process(GO:0042091) regulation of interleukin-10 biosynthetic process(GO:0045074)
0.1	0.2	GO:0002890	negative regulation of B cell mediated immunity(GO:0002713) negative regulation of immunoglobulin mediated immune response(GO:0002890)
0.1	0.5	GO:0033152	immunoglobulin V(D)J recombination(GO:0033152)
0.1	0.4	GO:0001574	ganglioside biosynthetic process(GO:0001574)
0.1	0.5	GO:0015014	heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.1	0.5	GO:1901339	activation of store-operated calcium channel activity(GO:0032237) regulation of store-operated calcium channel activity(GO:1901339) positive regulation of store-operated calcium channel activity(GO:1901341)
0.1	0.7	GO:0006538	glutamate catabolic process(GO:0006538)
0.1	0.1	GO:0035066	positive regulation of histone acetylation(GO:0035066) positive regulation of protein acetylation(GO:1901985) positive regulation of peptidyl-lysine acetylation(GO:2000758)
0.1	0.6	GO:0007195	adenylate cyclase-inhibiting dopamine receptor signaling pathway(GO:0007195)
0.1	0.3	GO:0045591	positive regulation of regulatory T cell differentiation(GO:0045591)
0.1	0.4	GO:0019987	obsolete negative regulation of anti-apoptosis(GO:0019987)
0.1	0.1	GO:0002326	B cell lineage commitment(GO:0002326)
0.1	0.3	GO:0043301	negative regulation of myeloid leukocyte mediated immunity(GO:0002887) negative regulation of leukocyte degranulation(GO:0043301)
0.1	0.5	GO:0006924	activation-induced cell death of T cells(GO:0006924)
0.1	0.5	GO:0002726	positive regulation of T cell cytokine production(GO:0002726)
0.1	0.3	GO:0002667	lymphocyte anergy(GO:0002249) regulation of T cell anergy(GO:0002667) positive regulation of T cell anergy(GO:0002669) T cell anergy(GO:0002870) regulation of lymphocyte anergy(GO:0002911) positive regulation of lymphocyte anergy(GO:0002913)
0.1	0.3	GO:0046813	receptor-mediated virion attachment to host cell(GO:0046813)
0.1	0.3	GO:0006772	thiamine metabolic process(GO:0006772)
0.1	0.3	GO:0010867	positive regulation of triglyceride biosynthetic process(GO:0010867)
0.1	0.3	GO:0018076	N-terminal peptidyl-lysine acetylation(GO:0018076)
0.1	0.3	GO:0018094	protein polyglycylation(GO:0018094)
0.1	0.3	GO:0010040	response to iron(II) ion(GO:0010040)
0.1	0.4	GO:0043951	negative regulation of cAMP-mediated signaling(GO:0043951)
0.1	0.5	GO:0046827	positive regulation of protein export from nucleus(GO:0046827)
0.1	0.1	GO:0050862	positive regulation of T cell receptor signaling pathway(GO:0050862)
0.1	0.3	GO:0007500	mesodermal cell fate determination(GO:0007500)
0.1	0.9	GO:0045086	positive regulation of interleukin-2 biosynthetic process(GO:0045086)
0.1	0.8	GO:0051828	entry into host cell(GO:0030260) entry into host(GO:0044409) entry into cell of other organism involved in symbiotic interaction(GO:0051806) entry into other organism involved in symbiotic interaction(GO:0051828)
0.1	0.2	GO:0014805	smooth muscle adaptation(GO:0014805)
0.1	0.1	GO:0002666	T cell tolerance induction(GO:0002517) regulation of T cell tolerance induction(GO:0002664) positive regulation of T cell tolerance induction(GO:0002666)
0.1	1.3	GO:0046834	lipid phosphorylation(GO:0046834)
0.1	0.2	GO:0002335	mature B cell differentiation involved in immune response(GO:0002313) mature B cell differentiation(GO:0002335)
0.1	0.2	GO:0032661	interleukin-18 production(GO:0032621) regulation of interleukin-18 production(GO:0032661)
0.1	2.0	GO:0050690	regulation of defense response to virus by virus(GO:0050690)
0.1	0.1	GO:0021938	smoothened signaling pathway involved in regulation of cerebellar granule cell precursor cell proliferation(GO:0021938)
0.1	0.2	GO:0021913	regulation of transcription from RNA polymerase II promoter involved in ventral spinal cord interneuron specification(GO:0021913)
0.1	0.5	GO:0007172	signal complex assembly(GO:0007172)
0.1	0.2	GO:0045056	transcytosis(GO:0045056)
0.1	0.3	GO:0048643	positive regulation of skeletal muscle tissue development(GO:0048643)
0.1	0.1	GO:0002677	negative regulation of chronic inflammatory response(GO:0002677)
0.1	0.3	GO:0045059	positive thymic T cell selection(GO:0045059)
0.1	0.4	GO:0007023	post-chaperonin tubulin folding pathway(GO:0007023)
0.1	0.2	GO:0006089	lactate metabolic process(GO:0006089)
0.1	0.5	GO:0008653	lipopolysaccharide metabolic process(GO:0008653)
0.1	0.1	GO:0048304	positive regulation of isotype switching to IgG isotypes(GO:0048304)
0.1	0.2	GO:0032203	telomere formation via telomerase(GO:0032203)
0.1	1.0	GO:0032012	regulation of ARF protein signal transduction(GO:0032012)
0.1	0.3	GO:0000089	mitotic metaphase(GO:0000089)
0.1	0.1	GO:0015015	heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.1	0.2	GO:0060235	lens induction in camera-type eye(GO:0060235)
0.1	0.1	GO:0006883	cellular sodium ion homeostasis(GO:0006883)
0.1	0.1	GO:0014874	response to stimulus involved in regulation of muscle adaptation(GO:0014874)
0.1	0.1	GO:0061154	endothelial tube morphogenesis(GO:0061154)
0.1	0.3	GO:0010642	negative regulation of platelet-derived growth factor receptor signaling pathway(GO:0010642)
0.1	0.3	GO:0045091	regulation of single stranded viral RNA replication via double stranded DNA intermediate(GO:0045091)
0.1	0.2	GO:0042118	endothelial cell activation(GO:0042118)
0.1	0.3	GO:0008588	release of cytoplasmic sequestered NF-kappaB(GO:0008588)
0.1	0.3	GO:0007097	nuclear migration(GO:0007097)
0.1	0.3	GO:0006685	sphingomyelin catabolic process(GO:0006685)
0.1	0.2	GO:0021529	spinal cord oligodendrocyte cell differentiation(GO:0021529) spinal cord oligodendrocyte cell fate specification(GO:0021530) oligodendrocyte cell fate specification(GO:0021778) glial cell fate specification(GO:0021780)
0.1	0.2	GO:0045990	carbon catabolite regulation of transcription(GO:0045990) regulation of transcription by glucose(GO:0046015)
0.1	0.1	GO:0046085	adenosine metabolic process(GO:0046085)
0.1	0.2	GO:0035025	positive regulation of Rho protein signal transduction(GO:0035025)
0.1	0.3	GO:0042989	sequestering of actin monomers(GO:0042989)
0.1	0.1	GO:0002093	auditory receptor cell morphogenesis(GO:0002093) auditory receptor cell stereocilium organization(GO:0060088)
0.1	0.1	GO:0002251	organ or tissue specific immune response(GO:0002251)
0.1	0.1	GO:0021860	pyramidal neuron differentiation(GO:0021859) pyramidal neuron development(GO:0021860)
0.1	0.1	GO:0071503	response to heparin(GO:0071503)
0.1	0.6	GO:0043508	negative regulation of JUN kinase activity(GO:0043508)
0.1	0.3	GO:0006198	cAMP catabolic process(GO:0006198)
0.1	0.4	GO:0002063	chondrocyte development(GO:0002063)
0.1	0.2	GO:0003197	endocardial cushion development(GO:0003197)
0.1	0.1	GO:0006925	inflammatory cell apoptotic process(GO:0006925)
0.1	0.3	GO:0001573	ganglioside metabolic process(GO:0001573)
0.1	0.2	GO:0001845	phagolysosome assembly(GO:0001845) phagosome maturation(GO:0090382)
0.1	0.2	GO:0070777	D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
0.1	0.2	GO:0003077	obsolete negative regulation of diuresis(GO:0003077)
0.1	0.2	GO:0034085	establishment of sister chromatid cohesion(GO:0034085) cohesin loading(GO:0071921) regulation of cohesin loading(GO:0071922)
0.1	0.2	GO:0002430	complement receptor mediated signaling pathway(GO:0002430)
0.1	0.7	GO:0034199	activation of protein kinase A activity(GO:0034199)
0.1	0.1	GO:0071635	negative regulation of transforming growth factor beta production(GO:0071635)
0.1	0.2	GO:0010614	negative regulation of cardiac muscle hypertrophy(GO:0010614)
0.1	0.3	GO:0048096	chromatin-mediated maintenance of transcription(GO:0048096)
0.0	0.6	GO:0000303	response to superoxide(GO:0000303)
0.0	0.2	GO:0035751	lysosomal lumen acidification(GO:0007042) regulation of lysosomal lumen pH(GO:0035751)
0.0	0.1	GO:0001820	serotonin secretion(GO:0001820)
0.0	0.1	GO:0048563	post-embryonic organ morphogenesis(GO:0048563)
0.0	1.5	GO:0050772	positive regulation of axonogenesis(GO:0050772)
0.0	0.1	GO:0052251	induction by organism of defense response of other organism involved in symbiotic interaction(GO:0052251)
0.0	0.4	GO:0060039	pericardium development(GO:0060039)
0.0	0.0	GO:0034983	peptidyl-lysine deacetylation(GO:0034983)
0.0	0.6	GO:0002637	regulation of immunoglobulin production(GO:0002637)
0.0	0.0	GO:0045589	regulation of regulatory T cell differentiation(GO:0045589)
0.0	0.1	GO:0006922	obsolete cleavage of lamin involved in execution phase of apoptosis(GO:0006922)
0.0	0.0	GO:0072540	T-helper cell lineage commitment(GO:0002295) CD4-positive, alpha-beta T cell lineage commitment(GO:0043373) memory T cell differentiation(GO:0043379) regulation of memory T cell differentiation(GO:0043380) positive regulation of memory T cell differentiation(GO:0043382) T-helper 17 type immune response(GO:0072538) T-helper 17 cell differentiation(GO:0072539) T-helper 17 cell lineage commitment(GO:0072540) regulation of T-helper 17 type immune response(GO:2000316) positive regulation of T-helper 17 type immune response(GO:2000318) regulation of T-helper 17 cell differentiation(GO:2000319) positive regulation of T-helper 17 cell differentiation(GO:2000321) regulation of T-helper 17 cell lineage commitment(GO:2000328) positive regulation of T-helper 17 cell lineage commitment(GO:2000330)
0.0	0.1	GO:0009405	pathogenesis(GO:0009405)
0.0	0.2	GO:0072531	pyrimidine-containing compound transmembrane transport(GO:0072531)
0.0	0.1	GO:0007035	vacuolar acidification(GO:0007035)
0.0	0.2	GO:0031340	positive regulation of vesicle fusion(GO:0031340)
0.0	0.1	GO:1903306	negative regulation of regulated secretory pathway(GO:1903306)
0.0	0.1	GO:0032808	lacrimal gland development(GO:0032808)
0.0	0.1	GO:0045722	positive regulation of gluconeogenesis(GO:0045722)
0.0	0.1	GO:0008053	mitochondrial fusion(GO:0008053)
0.0	0.6	GO:0006044	N-acetylglucosamine metabolic process(GO:0006044)
0.0	0.2	GO:0032776	DNA methylation on cytosine(GO:0032776) C-5 methylation of cytosine(GO:0090116)
0.0	0.0	GO:0070933	histone H3 deacetylation(GO:0070932) histone H4 deacetylation(GO:0070933)
0.0	0.1	GO:0043457	regulation of cellular respiration(GO:0043457)
0.0	0.0	GO:0014002	astrocyte development(GO:0014002)
0.0	0.0	GO:0031936	negative regulation of chromatin silencing(GO:0031936)
0.0	0.2	GO:0002098	tRNA wobble base modification(GO:0002097) tRNA wobble uridine modification(GO:0002098) tRNA thio-modification(GO:0034227)
0.0	0.3	GO:0030889	negative regulation of B cell proliferation(GO:0030889)
0.0	0.1	GO:0033033	negative regulation of myeloid cell apoptotic process(GO:0033033)
0.0	0.1	GO:0006659	phosphatidylserine biosynthetic process(GO:0006659)
0.0	0.5	GO:0031648	protein destabilization(GO:0031648)
0.0	0.2	GO:0000154	rRNA modification(GO:0000154)
0.0	0.1	GO:0010572	positive regulation of platelet activation(GO:0010572)
0.0	0.1	GO:0009448	gamma-aminobutyric acid metabolic process(GO:0009448)
0.0	0.1	GO:0006435	threonyl-tRNA aminoacylation(GO:0006435)
0.0	0.5	GO:0006607	NLS-bearing protein import into nucleus(GO:0006607)
0.0	0.1	GO:0072583	synaptic vesicle recycling(GO:0036465) synaptic vesicle endocytosis(GO:0048488) clathrin-mediated endocytosis(GO:0072583)
0.0	0.0	GO:0002019	regulation of renal output by angiotensin(GO:0002019)
0.0	0.1	GO:0035268	protein mannosylation(GO:0035268) protein O-linked mannosylation(GO:0035269) mannosylation(GO:0097502)
0.0	0.3	GO:0045745	positive regulation of G-protein coupled receptor protein signaling pathway(GO:0045745)
0.0	0.2	GO:0042518	negative regulation of tyrosine phosphorylation of Stat3 protein(GO:0042518)
0.0	0.0	GO:0071699	olfactory placode formation(GO:0030910) olfactory placode development(GO:0071698) olfactory placode morphogenesis(GO:0071699)
0.0	0.4	GO:0031146	SCF-dependent proteasomal ubiquitin-dependent protein catabolic process(GO:0031146)
0.0	0.0	GO:0032966	negative regulation of collagen biosynthetic process(GO:0032966)
0.0	0.2	GO:0017182	peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183)
0.0	0.1	GO:0032790	ribosome disassembly(GO:0032790)
0.0	0.1	GO:0002823	negative regulation of adaptive immune response(GO:0002820) negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains(GO:0002823)
0.0	0.1	GO:0071277	cellular response to calcium ion(GO:0071277)
0.0	0.2	GO:0007175	negative regulation of epidermal growth factor-activated receptor activity(GO:0007175)
0.0	0.1	GO:0036037	CD8-positive, alpha-beta T cell activation(GO:0036037) CD8-positive, alpha-beta T cell differentiation(GO:0043374)
0.0	0.1	GO:0002323	natural killer cell activation involved in immune response(GO:0002323) natural killer cell degranulation(GO:0043320)
0.0	0.2	GO:0051001	negative regulation of nitric-oxide synthase activity(GO:0051001)
0.0	0.0	GO:0071830	chylomicron remnant clearance(GO:0034382) triglyceride-rich lipoprotein particle clearance(GO:0071830)
0.0	0.1	GO:0061099	negative regulation of protein tyrosine kinase activity(GO:0061099)
0.0	0.1	GO:0071542	dopaminergic neuron differentiation(GO:0071542)
0.0	0.1	GO:0015864	pyrimidine nucleoside transport(GO:0015864)
0.0	0.0	GO:0043096	purine ribonucleoside salvage(GO:0006166) adenine salvage(GO:0006168) purine nucleobase salvage(GO:0043096) adenine metabolic process(GO:0046083) adenine biosynthetic process(GO:0046084)
0.0	0.2	GO:0007256	activation of JNKK activity(GO:0007256)
0.0	0.0	GO:2001259	positive regulation of calcium ion transmembrane transporter activity(GO:1901021) positive regulation of cation channel activity(GO:2001259)
0.0	0.3	GO:0000090	mitotic anaphase(GO:0000090)
0.0	0.7	GO:0006611	protein export from nucleus(GO:0006611)
0.0	0.0	GO:0048670	regulation of collateral sprouting(GO:0048670)
0.0	0.1	GO:0032733	positive regulation of interleukin-10 production(GO:0032733)
0.0	0.1	GO:0036072	intramembranous ossification(GO:0001957) direct ossification(GO:0036072)
0.0	0.1	GO:0042346	positive regulation of NF-kappaB import into nucleus(GO:0042346)
0.0	0.1	GO:0072526	pyridine-containing compound catabolic process(GO:0072526)
0.0	0.2	GO:0019883	antigen processing and presentation of endogenous antigen(GO:0019883)
0.0	0.1	GO:0033088	negative regulation of immature T cell proliferation(GO:0033087) negative regulation of immature T cell proliferation in thymus(GO:0033088)
0.0	0.7	GO:0045576	mast cell activation(GO:0045576)
0.0	0.1	GO:0051026	chiasma assembly(GO:0051026)
0.0	0.1	GO:0010758	regulation of macrophage chemotaxis(GO:0010758)
0.0	0.0	GO:0070669	response to interleukin-2(GO:0070669)
0.0	0.1	GO:0021681	cerebellar granular layer development(GO:0021681) cerebellar granular layer morphogenesis(GO:0021683) cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707)
0.0	0.1	GO:0033629	negative regulation of cell adhesion mediated by integrin(GO:0033629)
0.0	0.0	GO:0003211	cardiac chamber formation(GO:0003207) cardiac ventricle formation(GO:0003211)
0.0	0.1	GO:0010508	positive regulation of autophagy(GO:0010508)
0.0	1.4	GO:0031294	lymphocyte costimulation(GO:0031294) T cell costimulation(GO:0031295)
0.0	0.3	GO:0048741	skeletal muscle fiber development(GO:0048741)
0.0	0.1	GO:0009143	nucleoside triphosphate catabolic process(GO:0009143)
0.0	0.1	GO:0002689	negative regulation of leukocyte chemotaxis(GO:0002689)
0.0	0.1	GO:0070682	proteasome regulatory particle assembly(GO:0070682)
0.0	0.0	GO:0042596	fear response(GO:0042596)
0.0	0.1	GO:0006384	transcription initiation from RNA polymerase III promoter(GO:0006384)
0.0	0.1	GO:0021869	forebrain ventricular zone progenitor cell division(GO:0021869)
0.0	0.0	GO:0072216	positive regulation of metanephros development(GO:0072216)
0.0	0.1	GO:0031665	negative regulation of lipopolysaccharide-mediated signaling pathway(GO:0031665)
0.0	0.1	GO:0070857	regulation of bile acid biosynthetic process(GO:0070857) regulation of bile acid metabolic process(GO:1904251)
0.0	0.3	GO:0000085	mitotic G2 phase(GO:0000085) G2 phase(GO:0051319)
0.0	0.0	GO:0003148	outflow tract septum morphogenesis(GO:0003148)
0.0	0.1	GO:0042094	interleukin-2 biosynthetic process(GO:0042094)
0.0	0.1	GO:0006474	N-terminal protein amino acid acetylation(GO:0006474)
0.0	0.1	GO:0048711	positive regulation of astrocyte differentiation(GO:0048711)
0.0	0.3	GO:0032456	endocytic recycling(GO:0032456)
0.0	0.1	GO:0051322	anaphase(GO:0051322)
0.0	0.1	GO:0001955	blood vessel maturation(GO:0001955)
0.0	0.1	GO:0002418	immune response to tumor cell(GO:0002418)
0.0	0.1	GO:0050651	dermatan sulfate proteoglycan biosynthetic process(GO:0050651)
0.0	0.1	GO:0010737	protein kinase A signaling(GO:0010737)
0.0	0.0	GO:0031664	regulation of lipopolysaccharide-mediated signaling pathway(GO:0031664)
0.0	0.2	GO:0060040	retinal bipolar neuron differentiation(GO:0060040)
0.0	0.1	GO:0016199	axon midline choice point recognition(GO:0016199)
0.0	0.2	GO:1904376	negative regulation of establishment of protein localization to plasma membrane(GO:0090005) negative regulation of protein localization to plasma membrane(GO:1903077) negative regulation of protein localization to cell periphery(GO:1904376)
0.0	0.1	GO:0060437	lung growth(GO:0060437)
0.0	0.3	GO:0007217	tachykinin receptor signaling pathway(GO:0007217)
0.0	0.1	GO:0007130	synaptonemal complex assembly(GO:0007130)
0.0	0.2	GO:0000183	chromatin silencing at rDNA(GO:0000183)
0.0	0.2	GO:0000185	activation of MAPKKK activity(GO:0000185)
0.0	0.2	GO:0009298	GDP-mannose biosynthetic process(GO:0009298)
0.0	0.1	GO:0071392	cellular response to estradiol stimulus(GO:0071392)
0.0	0.0	GO:0034122	negative regulation of toll-like receptor signaling pathway(GO:0034122)
0.0	0.2	GO:0097094	cranial suture morphogenesis(GO:0060363) craniofacial suture morphogenesis(GO:0097094)
0.0	0.2	GO:0042832	response to protozoan(GO:0001562) defense response to protozoan(GO:0042832)
0.0	0.1	GO:0048087	positive regulation of developmental pigmentation(GO:0048087)
0.0	0.1	GO:0030174	regulation of DNA-dependent DNA replication initiation(GO:0030174)
0.0	0.1	GO:0006610	ribosomal protein import into nucleus(GO:0006610)
0.0	0.1	GO:0070340	detection of bacterial lipoprotein(GO:0042494) detection of bacterial lipopeptide(GO:0070340)
0.0	0.1	GO:0045136	development of secondary sexual characteristics(GO:0045136)
0.0	0.1	GO:2001012	mesenchymal cell differentiation involved in kidney development(GO:0072161) metanephric mesenchymal cell differentiation(GO:0072162) mesenchymal cell differentiation involved in renal system development(GO:2001012)
0.0	0.0	GO:0048617	embryonic foregut morphogenesis(GO:0048617)
0.0	0.1	GO:0010452	histone H3-K36 methylation(GO:0010452)
0.0	0.1	GO:0060214	endocardium formation(GO:0060214)
0.0	0.1	GO:0045117	azole transport(GO:0045117)
0.0	0.1	GO:0045354	interferon-alpha biosynthetic process(GO:0045349) regulation of interferon-alpha biosynthetic process(GO:0045354) positive regulation of interferon-alpha biosynthetic process(GO:0045356)
0.0	0.4	GO:0042517	positive regulation of tyrosine phosphorylation of Stat3 protein(GO:0042517)
0.0	0.1	GO:2000344	positive regulation of acrosome reaction(GO:2000344)
0.0	0.2	GO:0060770	negative regulation of epithelial cell proliferation involved in prostate gland development(GO:0060770)
0.0	0.1	GO:0007191	adenylate cyclase-activating dopamine receptor signaling pathway(GO:0007191)
0.0	0.1	GO:1902808	traversing start control point of mitotic cell cycle(GO:0007089) positive regulation of G1/S transition of mitotic cell cycle(GO:1900087) positive regulation of cell cycle G1/S phase transition(GO:1902808)
0.0	0.1	GO:1901978	positive regulation of spindle checkpoint(GO:0090232) regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090266) positive regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090267) positive regulation of cell cycle checkpoint(GO:1901978) regulation of mitotic spindle checkpoint(GO:1903504)
0.0	0.2	GO:0060765	regulation of androgen receptor signaling pathway(GO:0060765)
0.0	0.0	GO:0071421	manganese ion transmembrane transport(GO:0071421)
0.0	0.2	GO:0045948	positive regulation of translational initiation(GO:0045948)
0.0	0.1	GO:0007341	penetration of zona pellucida(GO:0007341)
0.0	0.1	GO:0050798	activated T cell proliferation(GO:0050798)
0.0	0.2	GO:0035235	ionotropic glutamate receptor signaling pathway(GO:0035235)
0.0	0.1	GO:0034723	DNA replication-dependent nucleosome organization(GO:0034723)
0.0	0.1	GO:0060218	hematopoietic stem cell differentiation(GO:0060218)
0.0	0.1	GO:1901797	negative regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043518) negative regulation of signal transduction by p53 class mediator(GO:1901797)
0.0	0.2	GO:0050860	regulation of T cell receptor signaling pathway(GO:0050856) negative regulation of antigen receptor-mediated signaling pathway(GO:0050858) negative regulation of T cell receptor signaling pathway(GO:0050860)
0.0	0.1	GO:0046426	negative regulation of JAK-STAT cascade(GO:0046426) negative regulation of STAT cascade(GO:1904893)
0.0	0.1	GO:0008291	acetylcholine metabolic process(GO:0008291) acetate ester metabolic process(GO:1900619)
0.0	0.1	GO:0048535	lymph node development(GO:0048535)
0.0	0.2	GO:0001662	behavioral fear response(GO:0001662)
0.0	0.2	GO:0008625	extrinsic apoptotic signaling pathway via death domain receptors(GO:0008625) extrinsic apoptotic signaling pathway(GO:0097191)
0.0	0.5	GO:0007190	activation of adenylate cyclase activity(GO:0007190)
0.0	0.1	GO:0071816	protein insertion into ER membrane(GO:0045048) tail-anchored membrane protein insertion into ER membrane(GO:0071816)
0.0	0.1	GO:0034625	fatty acid elongation, monounsaturated fatty acid(GO:0034625)
0.0	0.1	GO:0007343	egg activation(GO:0007343)
0.0	0.3	GO:1903038	negative regulation of T cell activation(GO:0050868) negative regulation of leukocyte cell-cell adhesion(GO:1903038)
0.0	0.0	GO:0030241	skeletal muscle myosin thick filament assembly(GO:0030241) myosin filament assembly(GO:0031034) striated muscle myosin thick filament assembly(GO:0071688)
0.0	0.2	GO:0006546	glycine catabolic process(GO:0006546)
0.0	0.1	GO:0000729	DNA double-strand break processing(GO:0000729)
0.0	0.1	GO:0015705	iodide transport(GO:0015705)
0.0	0.1	GO:0051382	kinetochore assembly(GO:0051382)
0.0	0.2	GO:0007158	neuron cell-cell adhesion(GO:0007158)
0.0	0.1	GO:0006477	protein sulfation(GO:0006477)
0.0	0.1	GO:0030505	inorganic diphosphate transport(GO:0030505)
0.0	0.1	GO:0033261	obsolete regulation of S phase(GO:0033261)
0.0	0.2	GO:0050910	detection of mechanical stimulus involved in sensory perception of sound(GO:0050910)
0.0	0.3	GO:0030252	growth hormone secretion(GO:0030252)
0.0	0.0	GO:0003402	planar cell polarity pathway involved in axis elongation(GO:0003402)
0.0	0.0	GO:0051665	membrane raft localization(GO:0051665)
0.0	0.1	GO:0021853	interneuron migration from the subpallium to the cortex(GO:0021830) cerebral cortex GABAergic interneuron migration(GO:0021853) cerebral cortex GABAergic interneuron development(GO:0021894) interneuron migration(GO:1904936)
0.0	0.1	GO:0048263	determination of dorsal/ventral asymmetry(GO:0048262) determination of dorsal identity(GO:0048263)
0.0	0.1	GO:0022614	membrane to membrane docking(GO:0022614)
0.0	0.1	GO:0009301	snRNA transcription(GO:0009301)
0.0	0.1	GO:0021571	rhombomere 5 development(GO:0021571)
0.0	0.1	GO:0006498	N-terminal protein lipidation(GO:0006498)
0.0	0.1	GO:0071428	rRNA-containing ribonucleoprotein complex export from nucleus(GO:0071428)
0.0	0.3	GO:0070536	protein K63-linked deubiquitination(GO:0070536)
0.0	0.1	GO:0032486	Rap protein signal transduction(GO:0032486)
0.0	0.1	GO:0046831	regulation of RNA export from nucleus(GO:0046831)
0.0	0.0	GO:0018119	protein nitrosylation(GO:0017014) peptidyl-cysteine S-nitrosylation(GO:0018119)
0.0	0.0	GO:0051970	negative regulation of transmission of nerve impulse(GO:0051970)
0.0	0.1	GO:0050710	negative regulation of cytokine secretion(GO:0050710)
0.0	0.0	GO:0097576	vacuole fusion(GO:0097576)
0.0	0.1	GO:0048251	elastic fiber assembly(GO:0048251)
0.0	0.5	GO:0006084	acetyl-CoA metabolic process(GO:0006084)
0.0	0.0	GO:0019673	GDP-mannose metabolic process(GO:0019673)
0.0	0.4	GO:0033209	tumor necrosis factor-mediated signaling pathway(GO:0033209)
0.0	0.0	GO:0070233	negative regulation of T cell apoptotic process(GO:0070233)
0.0	0.2	GO:0098927	early endosome to late endosome transport(GO:0045022) vesicle-mediated transport between endosomal compartments(GO:0098927)
0.0	0.1	GO:0048557	embryonic digestive tract morphogenesis(GO:0048557)
0.0	0.1	GO:0071168	protein localization to chromatin(GO:0071168)
0.0	0.1	GO:0043171	peptide catabolic process(GO:0043171)
0.0	0.1	GO:0009125	nucleoside monophosphate catabolic process(GO:0009125)
0.0	0.1	GO:0050957	equilibrioception(GO:0050957)
0.0	0.0	GO:0017085	response to insecticide(GO:0017085)
0.0	0.2	GO:0045737	positive regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045737) positive regulation of cyclin-dependent protein kinase activity(GO:1904031)
0.0	0.1	GO:0007000	nucleolus organization(GO:0007000)
0.0	0.1	GO:0021696	cerebellar cortex morphogenesis(GO:0021696)
0.0	0.1	GO:1903393	positive regulation of focal adhesion assembly(GO:0051894) positive regulation of cell junction assembly(GO:1901890) positive regulation of adherens junction organization(GO:1903393)
0.0	0.3	GO:0048536	spleen development(GO:0048536)
0.0	0.1	GO:0051657	maintenance of organelle location(GO:0051657)
0.0	1.6	GO:0007159	leukocyte cell-cell adhesion(GO:0007159)
0.0	0.0	GO:0002282	microglial cell activation involved in immune response(GO:0002282)
0.0	0.5	GO:0006997	nucleus organization(GO:0006997)
0.0	0.0	GO:0050849	negative regulation of calcium-mediated signaling(GO:0050849)
0.0	0.0	GO:0042996	regulation of Golgi to plasma membrane protein transport(GO:0042996)
0.0	0.1	GO:0016556	mRNA modification(GO:0016556)
0.0	0.1	GO:0008354	germ cell migration(GO:0008354)
0.0	0.1	GO:0048070	regulation of developmental pigmentation(GO:0048070)
0.0	0.1	GO:0051597	response to methylmercury(GO:0051597)
0.0	0.1	GO:0000266	mitochondrial fission(GO:0000266)
0.0	0.2	GO:0090114	vesicle targeting, rough ER to cis-Golgi(GO:0048207) COPII vesicle coating(GO:0048208) COPII-coated vesicle budding(GO:0090114)
0.0	0.0	GO:0032366	intracellular sterol transport(GO:0032366) intracellular cholesterol transport(GO:0032367)
0.0	0.0	GO:0072111	cell proliferation involved in kidney development(GO:0072111)
0.0	0.3	GO:0006004	fucose metabolic process(GO:0006004)
0.0	0.0	GO:0034088	maintenance of sister chromatid cohesion(GO:0034086) maintenance of mitotic sister chromatid cohesion(GO:0034088)
0.0	0.2	GO:0046688	response to copper ion(GO:0046688)
0.0	0.1	GO:0010591	regulation of lamellipodium assembly(GO:0010591)
0.0	0.0	GO:0046599	regulation of centriole replication(GO:0046599)
0.0	0.0	GO:0002475	antigen processing and presentation via MHC class Ib(GO:0002475)
0.0	0.0	GO:0021797	forebrain anterior/posterior pattern specification(GO:0021797)
0.0	0.1	GO:0034314	Arp2/3 complex-mediated actin nucleation(GO:0034314)
0.0	0.1	GO:0070301	cellular response to hydrogen peroxide(GO:0070301)
0.0	0.1	GO:0034755	iron ion transmembrane transport(GO:0034755)
0.0	0.0	GO:0050765	negative regulation of phagocytosis(GO:0050765)
0.0	0.1	GO:0019509	L-methionine biosynthetic process from methylthioadenosine(GO:0019509)
0.0	0.1	GO:0032878	regulation of establishment or maintenance of cell polarity(GO:0032878)
0.0	0.0	GO:2001021	negative regulation of response to DNA damage stimulus(GO:2001021)
0.0	0.0	GO:0034421	post-translational protein acetylation(GO:0034421)
0.0	0.1	GO:0021520	spinal cord motor neuron cell fate specification(GO:0021520)
0.0	0.0	GO:0071267	amino acid salvage(GO:0043102) L-methionine biosynthetic process(GO:0071265) L-methionine salvage(GO:0071267)
0.0	0.2	GO:0042982	amyloid precursor protein metabolic process(GO:0042982)
0.0	0.1	GO:0051547	regulation of keratinocyte migration(GO:0051547) positive regulation of keratinocyte migration(GO:0051549)
0.0	0.2	GO:0030101	natural killer cell activation(GO:0030101)
0.0	0.2	GO:0007339	binding of sperm to zona pellucida(GO:0007339)
0.0	0.1	GO:0046325	negative regulation of glucose import(GO:0046325)
0.0	0.1	GO:0045116	protein neddylation(GO:0045116)
0.0	0.0	GO:0051088	PMA-inducible membrane protein ectodomain proteolysis(GO:0051088)
0.0	0.1	GO:0045906	negative regulation of vasoconstriction(GO:0045906)
0.0	0.2	GO:0000076	DNA replication checkpoint(GO:0000076)
0.0	0.1	GO:0060023	soft palate development(GO:0060023)
0.0	0.0	GO:0019367	fatty acid elongation, saturated fatty acid(GO:0019367)
0.0	0.1	GO:0046329	negative regulation of JNK cascade(GO:0046329)
0.0	0.0	GO:0021799	cerebral cortex radially oriented cell migration(GO:0021799)
0.0	0.3	GO:0042776	mitochondrial ATP synthesis coupled proton transport(GO:0042776)
0.0	0.2	GO:0007076	mitotic chromosome condensation(GO:0007076)
0.0	0.1	GO:0046689	response to mercury ion(GO:0046689)
0.0	0.1	GO:0009048	dosage compensation by inactivation of X chromosome(GO:0009048)
0.0	0.1	GO:2001257	regulation of calcium ion transmembrane transporter activity(GO:1901019) regulation of cation channel activity(GO:2001257)
0.0	0.1	GO:0000733	DNA strand renaturation(GO:0000733)
0.0	0.0	GO:0032543	mitochondrial translation(GO:0032543)
0.0	0.1	GO:0010972	negative regulation of G2/M transition of mitotic cell cycle(GO:0010972) negative regulation of cell cycle G2/M phase transition(GO:1902750)
0.0	0.1	GO:0070837	dehydroascorbic acid transport(GO:0070837)
0.0	0.0	GO:0055078	sodium ion homeostasis(GO:0055078)
0.0	0.1	GO:0008608	attachment of spindle microtubules to kinetochore(GO:0008608)
0.0	0.1	GO:0098543	detection of other organism(GO:0098543)
0.0	0.0	GO:0010957	negative regulation of calcidiol 1-monooxygenase activity(GO:0010956) negative regulation of vitamin D biosynthetic process(GO:0010957) negative regulation of vitamin metabolic process(GO:0046137)
0.0	0.1	GO:0007141	male meiosis I(GO:0007141)
0.0	0.1	GO:0006545	glycine biosynthetic process(GO:0006545)
0.0	0.1	GO:0090400	stress-induced premature senescence(GO:0090400)
0.0	0.1	GO:0022027	interkinetic nuclear migration(GO:0022027)
0.0	0.2	GO:0016578	histone deubiquitination(GO:0016578)
0.0	0.0	GO:0045875	negative regulation of sister chromatid cohesion(GO:0045875)
0.0	0.1	GO:0019852	L-ascorbic acid metabolic process(GO:0019852)
0.0	0.0	GO:0010640	regulation of platelet-derived growth factor receptor signaling pathway(GO:0010640)
0.0	0.0	GO:0021561	facial nerve development(GO:0021561)
0.0	0.0	GO:0032100	positive regulation of response to food(GO:0032097) positive regulation of appetite(GO:0032100)
0.0	0.0	GO:0002862	negative regulation of inflammatory response to antigenic stimulus(GO:0002862)
0.0	0.1	GO:0006983	ER overload response(GO:0006983)
0.0	0.1	GO:0050718	positive regulation of interleukin-1 beta secretion(GO:0050718)
0.0	0.0	GO:0001992	regulation of systemic arterial blood pressure by vasopressin(GO:0001992)
0.0	0.1	GO:0002507	tolerance induction(GO:0002507)
0.0	0.0	GO:0070254	mucus secretion(GO:0070254)
0.0	0.2	GO:0010390	histone monoubiquitination(GO:0010390)
0.0	0.3	GO:0071377	cellular response to glucagon stimulus(GO:0071377)
0.0	0.0	GO:0032375	negative regulation of sterol transport(GO:0032372) negative regulation of cholesterol transport(GO:0032375)
0.0	0.1	GO:0045292	mRNA cis splicing, via spliceosome(GO:0045292)
0.0	0.0	GO:0043615	astrocyte cell migration(GO:0043615)
0.0	0.1	GO:0000012	single strand break repair(GO:0000012)
0.0	0.3	GO:0043967	histone H4 acetylation(GO:0043967)
0.0	0.0	GO:0032048	phosphatidylglycerol biosynthetic process(GO:0006655) cardiolipin metabolic process(GO:0032048) cardiolipin biosynthetic process(GO:0032049) phosphatidylglycerol metabolic process(GO:0046471)
0.0	0.0	GO:0006642	triglyceride mobilization(GO:0006642)
0.0	0.0	GO:0002407	dendritic cell chemotaxis(GO:0002407) dendritic cell migration(GO:0036336)
0.0	0.0	GO:0010919	regulation of inositol phosphate biosynthetic process(GO:0010919)
0.0	0.0	GO:0034110	regulation of homotypic cell-cell adhesion(GO:0034110)
0.0	0.1	GO:0045767	obsolete regulation of anti-apoptosis(GO:0045767)
0.0	0.1	GO:0006552	leucine catabolic process(GO:0006552)
0.0	0.0	GO:0060080	inhibitory postsynaptic potential(GO:0060080)
0.0	1.1	GO:0006959	humoral immune response(GO:0006959)
0.0	0.1	GO:0048710	regulation of astrocyte differentiation(GO:0048710)
0.0	0.1	GO:0035162	embryonic hemopoiesis(GO:0035162)
0.0	0.0	GO:0051446	positive regulation of meiotic nuclear division(GO:0045836) positive regulation of meiotic cell cycle(GO:0051446)
0.0	0.0	GO:0006111	regulation of gluconeogenesis(GO:0006111)
0.0	0.0	GO:0040016	embryonic cleavage(GO:0040016)
0.0	0.1	GO:0015801	aromatic amino acid transport(GO:0015801)
0.0	0.1	GO:0044321	cellular response to leptin stimulus(GO:0044320) response to leptin(GO:0044321)
0.0	0.0	GO:0039703	single stranded viral RNA replication via double stranded DNA intermediate(GO:0039692) viral RNA genome replication(GO:0039694) RNA replication(GO:0039703)
0.0	0.1	GO:0032986	nucleosome disassembly(GO:0006337) chromatin disassembly(GO:0031498) protein-DNA complex disassembly(GO:0032986)
0.0	0.3	GO:0006308	DNA catabolic process(GO:0006308)
0.0	0.0	GO:0010042	response to manganese ion(GO:0010042)
0.0	0.1	GO:0000389	mRNA 3'-splice site recognition(GO:0000389)
0.0	0.2	GO:0000045	autophagosome assembly(GO:0000045) autophagosome organization(GO:1905037)
0.0	0.2	GO:0006700	C21-steroid hormone biosynthetic process(GO:0006700)
0.0	0.0	GO:0033160	positive regulation of protein import into nucleus, translocation(GO:0033160)
0.0	0.1	GO:0071636	positive regulation of transforming growth factor beta production(GO:0071636)
0.0	0.1	GO:0042745	circadian sleep/wake cycle(GO:0042745)
0.0	0.2	GO:0006349	regulation of gene expression by genetic imprinting(GO:0006349)
0.0	0.0	GO:0060586	multicellular organismal iron ion homeostasis(GO:0060586)
0.0	0.0	GO:0010761	fibroblast migration(GO:0010761)
0.0	0.0	GO:0051451	myoblast migration(GO:0051451)
0.0	0.0	GO:0019441	tryptophan catabolic process to kynurenine(GO:0019441)
0.0	0.2	GO:0051282	release of sequestered calcium ion into cytosol(GO:0051209) regulation of sequestering of calcium ion(GO:0051282) negative regulation of sequestering of calcium ion(GO:0051283) calcium ion transmembrane import into cytosol(GO:0097553) calcium ion import into cytosol(GO:1902656)
0.0	0.0	GO:0006420	arginyl-tRNA aminoacylation(GO:0006420)
0.0	0.6	GO:0006120	mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.0	0.0	GO:0060272	embryonic skeletal joint morphogenesis(GO:0060272) embryonic skeletal joint development(GO:0072498)
0.0	0.1	GO:1903078	positive regulation of establishment of protein localization to plasma membrane(GO:0090004) positive regulation of protein localization to plasma membrane(GO:1903078) positive regulation of protein localization to cell periphery(GO:1904377)
0.0	0.0	GO:0045359	interferon-beta biosynthetic process(GO:0045350) regulation of interferon-beta biosynthetic process(GO:0045357) positive regulation of interferon-beta biosynthetic process(GO:0045359)
0.0	0.1	GO:0006657	CDP-choline pathway(GO:0006657)
0.0	0.1	GO:0006906	vesicle fusion(GO:0006906)
0.0	0.1	GO:0009804	phenylpropanoid metabolic process(GO:0009698) coumarin metabolic process(GO:0009804)
0.0	0.0	GO:0009221	pyrimidine deoxyribonucleotide biosynthetic process(GO:0009221)
0.0	0.0	GO:0032607	interferon-alpha production(GO:0032607) regulation of interferon-alpha production(GO:0032647)
0.0	0.0	GO:0000305	response to oxygen radical(GO:0000305)
0.0	0.0	GO:0006296	nucleotide-excision repair, DNA incision, 5'-to lesion(GO:0006296)
0.0	0.0	GO:0050435	beta-amyloid metabolic process(GO:0050435)
0.0	0.0	GO:0048934	peripheral nervous system neuron differentiation(GO:0048934)
0.0	0.0	GO:0009313	oligosaccharide catabolic process(GO:0009313)
0.0	0.1	GO:0046149	porphyrin-containing compound catabolic process(GO:0006787) tetrapyrrole catabolic process(GO:0033015) heme catabolic process(GO:0042167) pigment catabolic process(GO:0046149)
0.0	0.0	GO:2000008	regulation of protein localization to cell surface(GO:2000008)
0.0	0.1	GO:0006482	protein demethylation(GO:0006482) protein dealkylation(GO:0008214)
0.0	0.0	GO:0060839	endothelial cell fate commitment(GO:0060839)
0.0	0.0	GO:0040009	regulation of growth rate(GO:0040009)
0.0	0.1	GO:0051290	protein heterotetramerization(GO:0051290)
0.0	0.1	GO:0046784	viral mRNA export from host cell nucleus(GO:0046784)
0.0	0.1	GO:0030501	positive regulation of bone mineralization(GO:0030501)
0.0	0.1	GO:0010310	regulation of hydrogen peroxide metabolic process(GO:0010310)
0.0	0.1	GO:0045109	intermediate filament organization(GO:0045109)
0.0	0.1	GO:0009812	flavonoid metabolic process(GO:0009812)
0.0	0.0	GO:0046479	glycosylceramide catabolic process(GO:0046477) glycosphingolipid catabolic process(GO:0046479)
0.0	0.1	GO:0051457	maintenance of protein location in nucleus(GO:0051457)
0.0	0.0	GO:0031645	negative regulation of neurological system process(GO:0031645)
0.0	0.0	GO:0070265	necrotic cell death(GO:0070265)
0.0	0.0	GO:1901419	regulation of response to alcohol(GO:1901419)
0.0	0.0	GO:0071318	cellular response to ATP(GO:0071318)
0.0	0.0	GO:0021978	telencephalon regionalization(GO:0021978)
0.0	0.1	GO:0030903	notochord development(GO:0030903)
0.0	0.0	GO:0034379	very-low-density lipoprotein particle assembly(GO:0034379)
0.0	0.1	GO:0019042	viral latency(GO:0019042)
0.0	0.1	GO:0050847	progesterone receptor signaling pathway(GO:0050847)
0.0	0.2	GO:0009303	rRNA transcription(GO:0009303)
0.0	0.1	GO:0006554	lysine metabolic process(GO:0006553) lysine catabolic process(GO:0006554)
0.0	0.3	GO:0001709	cell fate determination(GO:0001709)
0.0	0.0	GO:0090279	regulation of calcium ion import(GO:0090279)
0.0	0.0	GO:0019886	antigen processing and presentation of exogenous peptide antigen via MHC class II(GO:0019886)
0.0	0.1	GO:0048268	clathrin coat assembly(GO:0048268)
0.0	0.2	GO:0045646	regulation of erythrocyte differentiation(GO:0045646)
0.0	0.1	GO:0010039	response to iron ion(GO:0010039)
0.0	0.0	GO:0007129	synapsis(GO:0007129) chromosome organization involved in meiotic cell cycle(GO:0070192)
0.0	0.1	GO:0021854	hypothalamus development(GO:0021854)
0.0	0.1	GO:0051205	protein insertion into membrane(GO:0051205)
0.0	0.3	GO:0015914	phospholipid transport(GO:0015914)
0.0	0.0	GO:0060122	inner ear receptor stereocilium organization(GO:0060122)
0.0	0.7	GO:0007605	sensory perception of sound(GO:0007605)
0.0	0.0	GO:0072047	proximal/distal pattern formation involved in nephron development(GO:0072047) specification of nephron tubule identity(GO:0072081)
0.0	0.1	GO:0006528	asparagine metabolic process(GO:0006528)
0.0	0.0	GO:0060456	positive regulation of digestive system process(GO:0060456)
0.0	0.0	GO:0001961	positive regulation of cytokine-mediated signaling pathway(GO:0001961)
0.0	0.0	GO:0060831	smoothened signaling pathway involved in dorsal/ventral neural tube patterning(GO:0060831)
0.0	0.0	GO:0048679	regulation of axon regeneration(GO:0048679) regulation of neuron projection regeneration(GO:0070570)
0.0	0.0	GO:0042088	T-helper 1 type immune response(GO:0042088)
0.0	0.3	GO:0006370	7-methylguanosine mRNA capping(GO:0006370)
0.0	0.0	GO:0001921	positive regulation of receptor recycling(GO:0001921)
0.0	0.0	GO:0018027	peptidyl-lysine dimethylation(GO:0018027)
0.0	0.0	GO:0030488	tRNA methylation(GO:0030488)
0.0	0.0	GO:0043267	negative regulation of potassium ion transport(GO:0043267)
0.0	0.0	GO:0070296	sarcoplasmic reticulum calcium ion transport(GO:0070296)
0.0	0.0	GO:0031342	negative regulation of cell killing(GO:0031342)
0.0	0.0	GO:0010457	centriole-centriole cohesion(GO:0010457)
0.0	0.0	GO:0016093	polyprenol metabolic process(GO:0016093) dolichol metabolic process(GO:0019348)
0.0	0.1	GO:0008535	respiratory chain complex IV assembly(GO:0008535)
0.0	0.0	GO:0030828	positive regulation of cGMP biosynthetic process(GO:0030828)
0.0	0.0	GO:0071371	cellular response to gonadotropin stimulus(GO:0071371)
0.0	0.0	GO:0007210	serotonin receptor signaling pathway(GO:0007210)
0.0	0.1	GO:0050962	detection of light stimulus involved in visual perception(GO:0050908) detection of light stimulus involved in sensory perception(GO:0050962)
0.0	0.1	GO:0006400	tRNA modification(GO:0006400)
0.0	0.0	GO:0050955	thermoception(GO:0050955)
0.0	0.2	GO:0016254	preassembly of GPI anchor in ER membrane(GO:0016254)
0.0	0.4	GO:0022904	respiratory electron transport chain(GO:0022904)
0.0	0.0	GO:1904358	positive regulation of telomere maintenance via telomerase(GO:0032212) positive regulation of telomere maintenance via telomere lengthening(GO:1904358)
0.0	0.0	GO:0000281	mitotic cytokinesis(GO:0000281)
0.0	0.0	GO:0046940	nucleoside monophosphate phosphorylation(GO:0046940)
0.0	0.1	GO:0008089	anterograde axonal transport(GO:0008089)
0.0	0.0	GO:0051307	resolution of meiotic recombination intermediates(GO:0000712) meiotic chromosome separation(GO:0051307)
0.0	0.0	GO:0019377	glycolipid catabolic process(GO:0019377)
0.0	0.1	GO:0002021	response to dietary excess(GO:0002021)
0.0	0.2	GO:0070585	protein localization to mitochondrion(GO:0070585)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	0.6	GO:0005826	actomyosin contractile ring(GO:0005826)
0.1	0.5	GO:0000300	obsolete peripheral to membrane of membrane fraction(GO:0000300)
0.1	1.5	GO:0005942	phosphatidylinositol 3-kinase complex(GO:0005942)
0.1	0.3	GO:0031235	intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.1	0.3	GO:0042105	alpha-beta T cell receptor complex(GO:0042105)
0.1	0.3	GO:0070022	transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.1	0.3	GO:0030895	apolipoprotein B mRNA editing enzyme complex(GO:0030895)
0.1	0.8	GO:0061200	clathrin-sculpted gamma-aminobutyric acid transport vesicle(GO:0061200) clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane(GO:0061202)
0.1	0.4	GO:0000137	Golgi cis cisterna(GO:0000137)
0.1	0.8	GO:0042101	T cell receptor complex(GO:0042101)
0.1	0.1	GO:0060203	clathrin-sculpted glutamate transport vesicle(GO:0060199) clathrin-sculpted glutamate transport vesicle membrane(GO:0060203)
0.1	0.4	GO:0070688	MLL5-L complex(GO:0070688)
0.1	0.7	GO:0001772	immunological synapse(GO:0001772)
0.1	0.2	GO:0044462	external encapsulating structure part(GO:0044462)
0.1	0.3	GO:0014701	junctional sarcoplasmic reticulum membrane(GO:0014701)
0.1	0.4	GO:0030673	axolemma(GO:0030673)
0.1	0.2	GO:0032009	early phagosome(GO:0032009)
0.0	0.1	GO:0005896	interleukin-6 receptor complex(GO:0005896)
0.0	0.0	GO:0030312	external encapsulating structure(GO:0030312)
0.0	0.1	GO:0032777	Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.0	0.3	GO:0008290	F-actin capping protein complex(GO:0008290)
0.0	0.5	GO:0032156	septin complex(GO:0031105) septin cytoskeleton(GO:0032156)
0.0	0.2	GO:0044453	integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229) nuclear membrane part(GO:0044453)
0.0	0.1	GO:0033270	paranode region of axon(GO:0033270)
0.0	0.1	GO:0000506	glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.0	0.6	GO:0016514	SWI/SNF complex(GO:0016514)
0.0	0.2	GO:0044224	juxtaparanode region of axon(GO:0044224)
0.0	0.2	GO:0005883	neurofilament(GO:0005883)
0.0	0.3	GO:0031095	platelet dense tubular network membrane(GO:0031095)
0.0	0.1	GO:0048179	activin receptor complex(GO:0048179)
0.0	0.1	GO:0032045	guanyl-nucleotide exchange factor complex(GO:0032045)
0.0	0.1	GO:0072487	MSL complex(GO:0072487)
0.0	0.0	GO:0001740	Barr body(GO:0001740)
0.0	0.1	GO:0070552	BRISC complex(GO:0070552)
0.0	0.2	GO:0000791	euchromatin(GO:0000791)
0.0	0.3	GO:0005697	telomerase holoenzyme complex(GO:0005697)
0.0	0.1	GO:0008540	proteasome regulatory particle, base subcomplex(GO:0008540)
0.0	0.1	GO:0032591	dendritic spine membrane(GO:0032591)
0.0	0.1	GO:0005827	polar microtubule(GO:0005827)
0.0	0.1	GO:0034992	microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.0	0.1	GO:0033553	rDNA heterochromatin(GO:0033553)
0.0	0.9	GO:0005626	obsolete insoluble fraction(GO:0005626)
0.0	0.1	GO:0000164	protein phosphatase type 1 complex(GO:0000164)
0.0	0.8	GO:0098636	integrin complex(GO:0008305) protein complex involved in cell adhesion(GO:0098636)
0.0	0.5	GO:0012507	ER to Golgi transport vesicle membrane(GO:0012507)
0.0	0.0	GO:0000138	Golgi trans cisterna(GO:0000138)
0.0	0.1	GO:0042788	polysomal ribosome(GO:0042788)
0.0	1.3	GO:0030173	integral component of Golgi membrane(GO:0030173)
0.0	0.3	GO:0043209	myelin sheath(GO:0043209)
0.0	0.1	GO:0031254	uropod(GO:0001931) cell trailing edge(GO:0031254)
0.0	0.6	GO:0031594	neuromuscular junction(GO:0031594)
0.0	0.1	GO:0071818	BAT3 complex(GO:0071818) ER membrane insertion complex(GO:0072379)
0.0	0.3	GO:0030313	cell envelope(GO:0030313)
0.0	0.1	GO:0042598	obsolete vesicular fraction(GO:0042598)
0.0	0.6	GO:0019005	SCF ubiquitin ligase complex(GO:0019005)
0.0	0.4	GO:0005892	acetylcholine-gated channel complex(GO:0005892)
0.0	0.4	GO:0005640	nuclear outer membrane(GO:0005640)
0.0	0.7	GO:0030175	filopodium(GO:0030175)
0.0	0.1	GO:0031904	endosome lumen(GO:0031904)
0.0	0.1	GO:0032590	dendrite membrane(GO:0032590)
0.0	0.3	GO:0031941	filamentous actin(GO:0031941)
0.0	0.1	GO:0016589	NURF complex(GO:0016589)
0.0	2.9	GO:0009897	external side of plasma membrane(GO:0009897)
0.0	0.1	GO:0034045	pre-autophagosomal structure membrane(GO:0034045)
0.0	0.1	GO:0001891	phagocytic cup(GO:0001891)
0.0	0.1	GO:0098984	asymmetric synapse(GO:0032279) neuron to neuron synapse(GO:0098984)
0.0	0.3	GO:0008278	cohesin complex(GO:0008278)
0.0	0.2	GO:0045261	proton-transporting ATP synthase complex, catalytic core F(1)(GO:0045261)
0.0	0.1	GO:0031463	Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0	0.1	GO:0005682	U5 snRNP(GO:0005682)
0.0	0.1	GO:0030891	VCB complex(GO:0030891)
0.0	0.1	GO:0033011	perinuclear theca(GO:0033011)
0.0	0.3	GO:0005844	polysome(GO:0005844)
0.0	0.2	GO:0034362	low-density lipoprotein particle(GO:0034362)
0.0	0.2	GO:0000780	condensed nuclear chromosome, centromeric region(GO:0000780)
0.0	0.0	GO:0000125	PCAF complex(GO:0000125)
0.0	0.1	GO:0005797	Golgi medial cisterna(GO:0005797)
0.0	0.1	GO:0031465	Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
0.0	0.1	GO:0045179	apical cortex(GO:0045179)
0.0	0.4	GO:0000307	cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.0	0.1	GO:0090576	RNA polymerase III transcription factor complex(GO:0090576)
0.0	0.1	GO:0030121	AP-1 adaptor complex(GO:0030121)
0.0	0.2	GO:0034518	mRNA cap binding complex(GO:0005845) RNA cap binding complex(GO:0034518)
0.0	0.1	GO:0032133	chromosome passenger complex(GO:0032133)
0.0	0.1	GO:0072357	PTW/PP1 phosphatase complex(GO:0072357)
0.0	0.3	GO:0033276	transcription factor TFTC complex(GO:0033276)
0.0	0.2	GO:0005744	mitochondrial inner membrane presequence translocase complex(GO:0005744)
0.0	0.0	GO:0005677	chromatin silencing complex(GO:0005677)
0.0	0.4	GO:0000159	protein phosphatase type 2A complex(GO:0000159)
0.0	0.2	GO:0005671	Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
0.0	0.2	GO:0005665	DNA-directed RNA polymerase II, core complex(GO:0005665)
0.0	0.2	GO:0005775	vacuolar lumen(GO:0005775)
0.0	0.1	GO:0032444	activin responsive factor complex(GO:0032444)
0.0	0.1	GO:0030914	STAGA complex(GO:0030914)
0.0	0.1	GO:0031616	spindle pole centrosome(GO:0031616)
0.0	0.2	GO:0000109	nucleotide-excision repair complex(GO:0000109)
0.0	0.0	GO:0031312	extrinsic component of organelle membrane(GO:0031312)
0.0	0.3	GO:0046930	pore complex(GO:0046930)
0.0	0.7	GO:0030964	mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0	0.1	GO:0005742	mitochondrial outer membrane translocase complex(GO:0005742)
0.0	0.1	GO:0042382	paraspeckles(GO:0042382)
0.0	0.0	GO:0000153	cytoplasmic ubiquitin ligase complex(GO:0000153)
0.0	0.2	GO:0017119	Golgi transport complex(GO:0017119)
0.0	0.0	GO:0045323	interleukin-1 receptor complex(GO:0045323)
0.0	0.1	GO:0034451	centriolar satellite(GO:0034451)
0.0	0.0	GO:0005577	fibrinogen complex(GO:0005577)
0.0	0.2	GO:0005868	cytoplasmic dynein complex(GO:0005868)
0.0	0.7	GO:0055037	recycling endosome(GO:0055037)
0.0	0.1	GO:0031258	lamellipodium membrane(GO:0031258)
0.0	0.1	GO:0000346	transcription export complex(GO:0000346)
0.0	0.1	GO:0035631	CD40 receptor complex(GO:0035631)
0.0	0.9	GO:0000786	nucleosome(GO:0000786)
0.0	0.3	GO:0031519	PcG protein complex(GO:0031519)
0.0	0.1	GO:0031080	nuclear pore outer ring(GO:0031080)
0.0	0.8	GO:0030027	lamellipodium(GO:0030027)
0.0	0.1	GO:0070461	SAGA-type complex(GO:0070461)
0.0	0.1	GO:0051233	spindle midzone(GO:0051233)
0.0	0.2	GO:0005884	actin filament(GO:0005884)
0.0	0.8	GO:0005643	nuclear pore(GO:0005643)
0.0	0.0	GO:0031010	ISWI-type complex(GO:0031010)
0.0	0.3	GO:0071339	MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339)
0.0	0.0	GO:0031205	endoplasmic reticulum Sec complex(GO:0031205)
0.0	0.2	GO:0005852	eukaryotic translation initiation factor 3 complex(GO:0005852)
0.0	0.1	GO:0000940	condensed chromosome outer kinetochore(GO:0000940)
0.0	0.1	GO:0005721	pericentric heterochromatin(GO:0005721)
0.0	0.1	GO:0030904	retromer complex(GO:0030904)
0.0	0.0	GO:0030008	TRAPP complex(GO:0030008)
0.0	0.1	GO:0005732	small nucleolar ribonucleoprotein complex(GO:0005732)
0.0	0.1	GO:0000803	sex chromosome(GO:0000803)
0.0	0.1	GO:0008180	COP9 signalosome(GO:0008180)
0.0	0.2	GO:0032153	cell division site(GO:0032153) cell division site part(GO:0032155)
0.0	0.1	GO:0016585	obsolete chromatin remodeling complex(GO:0016585)
0.0	0.0	GO:0000800	lateral element(GO:0000800)
0.0	0.0	GO:0016533	cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533)
0.0	0.4	GO:0016592	mediator complex(GO:0016592)
0.0	0.4	GO:0005834	heterotrimeric G-protein complex(GO:0005834)
0.0	0.1	GO:0016461	unconventional myosin complex(GO:0016461)
0.0	0.1	GO:0034706	sodium channel complex(GO:0034706)
0.0	0.1	GO:0043198	dendritic shaft(GO:0043198)
0.0	1.0	GO:0008076	voltage-gated potassium channel complex(GO:0008076)
0.0	0.3	GO:0000932	cytoplasmic mRNA processing body(GO:0000932)
0.0	0.0	GO:0005787	signal peptidase complex(GO:0005787)
0.0	0.0	GO:0001652	granular component(GO:0001652)
0.0	0.2	GO:0005763	organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.0	0.8	GO:0005938	cell cortex(GO:0005938)
0.0	0.1	GO:0044815	DNA packaging complex(GO:0044815)
0.0	0.2	GO:0034364	high-density lipoprotein particle(GO:0034364)
0.0	0.1	GO:0005851	eukaryotic translation initiation factor 2B complex(GO:0005851)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	2.1	GO:0016493	C-C chemokine receptor activity(GO:0016493)
0.2	0.6	GO:0035184	histone threonine kinase activity(GO:0035184)
0.2	1.1	GO:0052813	phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) phosphatidylinositol bisphosphate kinase activity(GO:0052813)
0.2	0.6	GO:0004351	glutamate decarboxylase activity(GO:0004351)
0.2	0.5	GO:0004911	interleukin-2 receptor activity(GO:0004911)
0.1	0.4	GO:0004476	mannose-6-phosphate isomerase activity(GO:0004476)
0.1	0.4	GO:0003836	beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.1	0.3	GO:0016286	small conductance calcium-activated potassium channel activity(GO:0016286)
0.1	0.2	GO:0052659	inositol-1,4,5-trisphosphate 5-phosphatase activity(GO:0052658) inositol-1,3,4,5-tetrakisphosphate 5-phosphatase activity(GO:0052659)
0.1	0.4	GO:0015925	galactosidase activity(GO:0015925)
0.1	0.3	GO:0046935	1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.1	0.8	GO:0050700	CARD domain binding(GO:0050700)
0.1	0.6	GO:0001609	G-protein coupled adenosine receptor activity(GO:0001609)
0.1	0.3	GO:0042608	T cell receptor binding(GO:0042608)
0.1	0.4	GO:0070492	oligosaccharide binding(GO:0070492)
0.1	0.3	GO:0070735	protein-glycine ligase activity(GO:0070735)
0.1	0.3	GO:0016309	1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
0.1	0.2	GO:0005134	interleukin-2 receptor binding(GO:0005134)
0.1	0.2	GO:0016312	inositol bisphosphate phosphatase activity(GO:0016312)
0.1	0.2	GO:0030368	interleukin-17 receptor activity(GO:0030368)
0.1	0.2	GO:0003987	acetate-CoA ligase activity(GO:0003987)
0.1	0.4	GO:0016494	C-X-C chemokine receptor activity(GO:0016494)
0.1	0.2	GO:0098599	palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.1	0.2	GO:0035005	1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.1	0.2	GO:0047756	chondroitin 4-sulfotransferase activity(GO:0047756)
0.1	0.2	GO:0003876	AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.1	0.4	GO:0004767	sphingomyelin phosphodiesterase activity(GO:0004767)
0.1	0.2	GO:0015379	potassium:chloride symporter activity(GO:0015379)
0.1	0.1	GO:0033691	sialic acid binding(GO:0033691)
0.1	0.3	GO:0004046	aminoacylase activity(GO:0004046)
0.1	2.7	GO:0001948	glycoprotein binding(GO:0001948)
0.1	1.0	GO:0005086	ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.1	0.5	GO:0030332	cyclin binding(GO:0030332)
0.1	0.7	GO:0005031	tumor necrosis factor-activated receptor activity(GO:0005031)
0.1	0.2	GO:0047631	ADP-ribose diphosphatase activity(GO:0047631)
0.1	2.9	GO:0005070	SH3/SH2 adaptor activity(GO:0005070)
0.1	0.1	GO:0046030	inositol-polyphosphate 5-phosphatase activity(GO:0004445) inositol trisphosphate phosphatase activity(GO:0046030)
0.1	0.2	GO:0005049	nuclear export signal receptor activity(GO:0005049)
0.1	0.5	GO:0015278	calcium-release channel activity(GO:0015278) ligand-gated calcium channel activity(GO:0099604)
0.1	0.7	GO:0004697	protein kinase C activity(GO:0004697)
0.1	0.6	GO:0043425	bHLH transcription factor binding(GO:0043425)
0.1	0.4	GO:0050811	GABA receptor binding(GO:0050811)
0.1	0.5	GO:0030276	clathrin binding(GO:0030276)
0.1	0.4	GO:0004931	extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
0.1	0.3	GO:0004985	opioid receptor activity(GO:0004985)
0.1	0.3	GO:0008093	cytoskeletal adaptor activity(GO:0008093)
0.1	0.2	GO:0003720	telomerase activity(GO:0003720) RNA-directed DNA polymerase activity(GO:0003964)
0.1	0.3	GO:0004563	beta-N-acetylhexosaminidase activity(GO:0004563)
0.1	0.9	GO:0043027	cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.1	0.4	GO:0004467	long-chain fatty acid-CoA ligase activity(GO:0004467)
0.1	0.2	GO:0008420	CTD phosphatase activity(GO:0008420)
0.1	0.2	GO:0004875	complement receptor activity(GO:0004875)
0.1	0.4	GO:0043014	alpha-tubulin binding(GO:0043014)
0.1	0.1	GO:0034237	protein kinase A regulatory subunit binding(GO:0034237)
0.1	0.2	GO:0008853	exodeoxyribonuclease III activity(GO:0008853)
0.1	0.4	GO:0004691	cAMP-dependent protein kinase activity(GO:0004691)
0.0	0.1	GO:0031957	very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.0	0.1	GO:0004591	oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591)
0.0	0.3	GO:0008266	poly(U) RNA binding(GO:0008266)
0.0	0.2	GO:0005131	growth hormone receptor binding(GO:0005131)
0.0	0.3	GO:0004950	G-protein coupled chemoattractant receptor activity(GO:0001637) chemokine receptor activity(GO:0004950)
0.0	0.4	GO:0005522	profilin binding(GO:0005522)
0.0	0.3	GO:0070577	lysine-acetylated histone binding(GO:0070577)
0.0	0.1	GO:0042799	histone methyltransferase activity (H4-K20 specific)(GO:0042799)
0.0	0.1	GO:0004792	thiosulfate sulfurtransferase activity(GO:0004792)
0.0	0.2	GO:0003886	DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.0	0.2	GO:0047238	glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity(GO:0047238)
0.0	0.2	GO:0051864	histone demethylase activity (H3-K36 specific)(GO:0051864)
0.0	0.7	GO:0048487	beta-tubulin binding(GO:0048487)
0.0	0.2	GO:0030235	nitric-oxide synthase regulator activity(GO:0030235)
0.0	0.1	GO:0004465	lipoprotein lipase activity(GO:0004465)
0.0	0.6	GO:0004016	adenylate cyclase activity(GO:0004016)
0.0	0.5	GO:0005251	delayed rectifier potassium channel activity(GO:0005251)
0.0	0.1	GO:0004829	threonine-tRNA ligase activity(GO:0004829)
0.0	0.1	GO:0008454	alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.0	0.1	GO:0050698	proteoglycan sulfotransferase activity(GO:0050698)
0.0	0.2	GO:0016997	exo-alpha-sialidase activity(GO:0004308) alpha-sialidase activity(GO:0016997)
0.0	0.1	GO:0004582	dolichyl-phosphate beta-D-mannosyltransferase activity(GO:0004582)
0.0	0.2	GO:0005381	iron ion transmembrane transporter activity(GO:0005381)
0.0	0.0	GO:0001098	basal transcription machinery binding(GO:0001098) basal RNA polymerase II transcription machinery binding(GO:0001099)
0.0	0.1	GO:0016361	activin receptor activity, type I(GO:0016361)
0.0	0.1	GO:0070053	thrombospondin receptor activity(GO:0070053)
0.0	0.2	GO:0004064	arylesterase activity(GO:0004064)
0.0	0.1	GO:0016842	amidine-lyase activity(GO:0016842)
0.0	0.1	GO:0043533	inositol 1,3,4,5 tetrakisphosphate binding(GO:0043533)
0.0	0.1	GO:0050508	glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0050508)
0.0	0.1	GO:0008296	3'-5'-exodeoxyribonuclease activity(GO:0008296)
0.0	0.2	GO:0004126	cytidine deaminase activity(GO:0004126)
0.0	0.7	GO:0043621	protein self-association(GO:0043621)
0.0	0.3	GO:0035251	UDP-glucosyltransferase activity(GO:0035251)
0.0	0.2	GO:0001012	RNA polymerase II regulatory region sequence-specific DNA binding(GO:0000977) RNA polymerase II regulatory region DNA binding(GO:0001012)
0.0	0.3	GO:0005388	calcium-transporting ATPase activity(GO:0005388)
0.0	0.4	GO:0070064	proline-rich region binding(GO:0070064)
0.0	0.2	GO:0042834	peptidoglycan binding(GO:0042834)
0.0	0.3	GO:0004571	mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.0	0.1	GO:0008109	N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109)
0.0	0.2	GO:0031491	nucleosome binding(GO:0031491)
0.0	0.1	GO:0004449	isocitrate dehydrogenase (NAD+) activity(GO:0004449)
0.0	0.1	GO:0098518	polynucleotide phosphatase activity(GO:0098518)
0.0	0.2	GO:0019992	diacylglycerol binding(GO:0019992)
0.0	0.2	GO:0005314	high-affinity glutamate transmembrane transporter activity(GO:0005314)
0.0	0.1	GO:0019788	NEDD8 transferase activity(GO:0019788)
0.0	0.4	GO:0000155	phosphorelay sensor kinase activity(GO:0000155)
0.0	0.1	GO:0035197	siRNA binding(GO:0035197)
0.0	0.1	GO:0001591	dopamine neurotransmitter receptor activity, coupled via Gi/Go(GO:0001591)
0.0	0.1	GO:0004897	ciliary neurotrophic factor receptor activity(GO:0004897)
0.0	0.2	GO:0008467	[heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.0	0.4	GO:0016888	endodeoxyribonuclease activity, producing 5'-phosphomonoesters(GO:0016888)
0.0	1.3	GO:0004896	cytokine receptor activity(GO:0004896)
0.0	0.2	GO:0016308	1-phosphatidylinositol-4-phosphate 5-kinase activity(GO:0016308)
0.0	0.0	GO:0034236	protein kinase A catalytic subunit binding(GO:0034236)
0.0	0.2	GO:0015165	pyrimidine nucleotide-sugar transmembrane transporter activity(GO:0015165)
0.0	0.1	GO:0008545	JUN kinase kinase activity(GO:0008545)
0.0	0.1	GO:0008332	low voltage-gated calcium channel activity(GO:0008332)
0.0	0.1	GO:0004802	transketolase activity(GO:0004802)
0.0	0.1	GO:0008649	rRNA methyltransferase activity(GO:0008649)
0.0	0.5	GO:0035064	methylated histone binding(GO:0035064)
0.0	0.3	GO:0008239	dipeptidyl-peptidase activity(GO:0008239)
0.0	0.1	GO:0004517	nitric-oxide synthase activity(GO:0004517)
0.0	0.1	GO:0005000	vasopressin receptor activity(GO:0005000)
0.0	0.5	GO:0008373	sialyltransferase activity(GO:0008373)
0.0	0.4	GO:0005487	nucleocytoplasmic transporter activity(GO:0005487)
0.0	0.1	GO:0034481	chondroitin sulfotransferase activity(GO:0034481)
0.0	0.1	GO:0046975	histone methyltransferase activity (H3-K36 specific)(GO:0046975)
0.0	0.1	GO:0004726	non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.0	0.3	GO:0046875	ephrin receptor binding(GO:0046875)
0.0	0.1	GO:0008035	high-density lipoprotein particle binding(GO:0008035)
0.0	0.4	GO:0005527	macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.0	0.3	GO:0005095	GTPase inhibitor activity(GO:0005095)
0.0	0.2	GO:0046920	alpha-(1->3)-fucosyltransferase activity(GO:0046920)
0.0	0.2	GO:0031701	angiotensin receptor binding(GO:0031701)
0.0	0.3	GO:0001619	obsolete lysosphingolipid and lysophosphatidic acid receptor activity(GO:0001619)
0.0	0.1	GO:0043024	ribosomal small subunit binding(GO:0043024)
0.0	0.2	GO:0048531	beta-1,3-galactosyltransferase activity(GO:0048531)
0.0	0.2	GO:0004703	G-protein coupled receptor kinase activity(GO:0004703)
0.0	0.1	GO:0004994	somatostatin receptor activity(GO:0004994)
0.0	0.4	GO:0004012	phospholipid-translocating ATPase activity(GO:0004012)
0.0	0.1	GO:0016715	dopamine beta-monooxygenase activity(GO:0004500) oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen(GO:0016715)
0.0	0.8	GO:0004715	non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.0	0.2	GO:0015288	porin activity(GO:0015288)
0.0	0.1	GO:0046404	ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity(GO:0046404) polydeoxyribonucleotide kinase activity(GO:0051733) ATP-dependent polynucleotide kinase activity(GO:0051734)
0.0	0.2	GO:0050431	transforming growth factor beta binding(GO:0050431)
0.0	0.3	GO:0017017	MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.0	0.1	GO:0019911	structural constituent of myelin sheath(GO:0019911)
0.0	0.0	GO:0005127	ciliary neurotrophic factor receptor binding(GO:0005127)
0.0	0.1	GO:0004047	aminomethyltransferase activity(GO:0004047)
0.0	0.0	GO:0017002	activin-activated receptor activity(GO:0017002)
0.0	0.0	GO:0042166	acetylcholine binding(GO:0042166)
0.0	2.9	GO:0003702	obsolete RNA polymerase II transcription factor activity(GO:0003702)
0.0	0.1	GO:0004704	NF-kappaB-inducing kinase activity(GO:0004704)
0.0	1.3	GO:0008301	DNA binding, bending(GO:0008301)
0.0	0.1	GO:0016857	racemase and epimerase activity, acting on carbohydrates and derivatives(GO:0016857)
0.0	0.1	GO:0008568	microtubule-severing ATPase activity(GO:0008568)
0.0	0.1	GO:0016208	AMP binding(GO:0016208)
0.0	0.1	GO:0004514	nicotinate-nucleotide diphosphorylase (carboxylating) activity(GO:0004514)
0.0	0.1	GO:0004972	NMDA glutamate receptor activity(GO:0004972)
0.0	0.1	GO:0015038	glutathione disulfide oxidoreductase activity(GO:0015038)
0.0	0.5	GO:0001608	G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.0	0.4	GO:0005164	tumor necrosis factor receptor binding(GO:0005164)
0.0	0.1	GO:0042910	xenobiotic-transporting ATPase activity(GO:0008559) xenobiotic transporter activity(GO:0042910)
0.0	0.4	GO:0004889	acetylcholine-activated cation-selective channel activity(GO:0004889)
0.0	0.0	GO:0015018	galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity(GO:0015018)
0.0	0.1	GO:0005111	type 2 fibroblast growth factor receptor binding(GO:0005111)
0.0	0.1	GO:0004032	alditol:NADP+ 1-oxidoreductase activity(GO:0004032)
0.0	0.0	GO:0002060	purine nucleobase binding(GO:0002060)
0.0	0.1	GO:0030881	beta-2-microglobulin binding(GO:0030881)
0.0	0.1	GO:0004142	diacylglycerol cholinephosphotransferase activity(GO:0004142)
0.0	0.6	GO:0008138	protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.0	0.1	GO:0016728	ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
0.0	0.1	GO:0071208	histone pre-mRNA DCP binding(GO:0071208)
0.0	0.1	GO:0001727	lipid kinase activity(GO:0001727)
0.0	0.1	GO:0004427	inorganic diphosphatase activity(GO:0004427)
0.0	0.0	GO:0042289	MHC class II protein binding(GO:0042289)
0.0	0.1	GO:0008475	procollagen-lysine 5-dioxygenase activity(GO:0008475)
0.0	0.1	GO:0004949	cannabinoid receptor activity(GO:0004949)
0.0	0.0	GO:0051731	polynucleotide 5'-hydroxyl-kinase activity(GO:0051731)
0.0	0.0	GO:0008241	peptidyl-dipeptidase activity(GO:0008241)
0.0	0.1	GO:0005176	ErbB-2 class receptor binding(GO:0005176)
0.0	0.0	GO:0043008	ATP-dependent protein binding(GO:0043008)
0.0	0.1	GO:0016774	phosphotransferase activity, carboxyl group as acceptor(GO:0016774)
0.0	0.1	GO:0005346	purine ribonucleotide transmembrane transporter activity(GO:0005346)
0.0	0.1	GO:0004999	vasoactive intestinal polypeptide receptor activity(GO:0004999)
0.0	0.1	GO:0033300	dehydroascorbic acid transporter activity(GO:0033300)
0.0	0.0	GO:0004516	nicotinate phosphoribosyltransferase activity(GO:0004516)
0.0	0.1	GO:0019239	deaminase activity(GO:0019239)
0.0	0.1	GO:0004957	prostaglandin E receptor activity(GO:0004957)
0.0	0.2	GO:0070491	repressing transcription factor binding(GO:0070491)
0.0	0.2	GO:0008171	O-methyltransferase activity(GO:0008171)
0.0	0.1	GO:0030292	protein tyrosine kinase inhibitor activity(GO:0030292)
0.0	0.1	GO:0035241	protein-arginine omega-N monomethyltransferase activity(GO:0035241)
0.0	0.4	GO:0016814	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines(GO:0016814)
0.0	0.1	GO:0004396	hexokinase activity(GO:0004396)
0.0	0.1	GO:0004967	glucagon receptor activity(GO:0004967)
0.0	0.1	GO:0032552	deoxyribonucleotide binding(GO:0032552)
0.0	0.1	GO:0004966	galanin receptor activity(GO:0004966)
0.0	0.2	GO:0032813	tumor necrosis factor receptor superfamily binding(GO:0032813)
0.0	0.1	GO:0015215	nucleotide transmembrane transporter activity(GO:0015215)
0.0	0.0	GO:0004955	prostaglandin receptor activity(GO:0004955)
0.0	0.0	GO:0004954	prostanoid receptor activity(GO:0004954)
0.0	0.1	GO:0003785	actin monomer binding(GO:0003785)
0.0	0.1	GO:0015347	sodium-independent organic anion transmembrane transporter activity(GO:0015347)
0.0	0.4	GO:0004114	3',5'-cyclic-nucleotide phosphodiesterase activity(GO:0004114)
0.0	0.5	GO:0042393	histone binding(GO:0042393)
0.0	0.1	GO:0000739	obsolete DNA strand annealing activity(GO:0000739)
0.0	0.4	GO:0003725	double-stranded RNA binding(GO:0003725)
0.0	0.4	GO:0004177	aminopeptidase activity(GO:0004177)
0.0	0.1	GO:0008517	folic acid transporter activity(GO:0008517)
0.0	0.5	GO:0003887	DNA-directed DNA polymerase activity(GO:0003887)
0.0	0.0	GO:0016744	transferase activity, transferring aldehyde or ketonic groups(GO:0016744)
0.0	0.7	GO:0050136	NADH dehydrogenase activity(GO:0003954) NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0	0.1	GO:0003847	1-alkyl-2-acetylglycerophosphocholine esterase activity(GO:0003847)
0.0	0.1	GO:0017080	sodium channel regulator activity(GO:0017080)
0.0	0.1	GO:0004614	phosphoglucomutase activity(GO:0004614)
0.0	0.1	GO:0050815	phosphoserine binding(GO:0050815)
0.0	0.1	GO:0031435	mitogen-activated protein kinase kinase kinase binding(GO:0031435)
0.0	0.1	GO:0019136	deoxynucleoside kinase activity(GO:0019136)
0.0	0.1	GO:0030544	Hsp70 protein binding(GO:0030544)
0.0	0.1	GO:0000400	four-way junction DNA binding(GO:0000400)
0.0	0.1	GO:0050544	arachidonic acid binding(GO:0050544)
0.0	0.1	GO:0016595	glutamate binding(GO:0016595)
0.0	0.0	GO:0050510	N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity(GO:0050510)
0.0	0.2	GO:0031593	polyubiquitin binding(GO:0031593)
0.0	0.2	GO:0005246	calcium channel regulator activity(GO:0005246)
0.0	0.0	GO:0004311	farnesyltranstransferase activity(GO:0004311)
0.0	0.4	GO:0003950	NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.0	0.1	GO:0043522	leucine zipper domain binding(GO:0043522)
0.0	0.2	GO:0005548	phospholipid transporter activity(GO:0005548)
0.0	0.1	GO:0034593	phosphatidylinositol bisphosphate phosphatase activity(GO:0034593)
0.0	0.0	GO:0004814	arginine-tRNA ligase activity(GO:0004814)
0.0	0.1	GO:0016778	diphosphotransferase activity(GO:0016778)
0.0	0.1	GO:0001085	RNA polymerase II transcription factor binding(GO:0001085)
0.0	0.1	GO:0070087	chromo shadow domain binding(GO:0070087)
0.0	0.0	GO:0000064	L-ornithine transmembrane transporter activity(GO:0000064)
0.0	0.0	GO:0071723	lipopeptide binding(GO:0071723)
0.0	0.0	GO:0048156	tau protein binding(GO:0048156)
0.0	0.0	GO:0016303	1-phosphatidylinositol-3-kinase activity(GO:0016303)
0.0	0.3	GO:0051219	phosphoprotein binding(GO:0051219)
0.0	0.1	GO:0070579	methylcytosine dioxygenase activity(GO:0070579)
0.0	0.0	GO:0031849	olfactory receptor binding(GO:0031849)
0.0	0.0	GO:0004706	JUN kinase kinase kinase activity(GO:0004706)
0.0	0.5	GO:0019903	protein phosphatase binding(GO:0019903)
0.0	0.0	GO:0004774	succinate-CoA ligase activity(GO:0004774)
0.0	0.1	GO:0031996	thioesterase binding(GO:0031996)
0.0	0.1	GO:0070513	death domain binding(GO:0070513)
0.0	0.2	GO:0008601	protein phosphatase type 2A regulator activity(GO:0008601)
0.0	0.0	GO:0005275	amine transmembrane transporter activity(GO:0005275)
0.0	0.1	GO:0004459	L-lactate dehydrogenase activity(GO:0004459)
0.0	0.1	GO:0003688	DNA replication origin binding(GO:0003688)
0.0	0.0	GO:0004607	phosphatidylcholine-sterol O-acyltransferase activity(GO:0004607)
0.0	0.4	GO:0001104	transcription factor activity, RNA polymerase II transcription factor binding(GO:0001076) RNA polymerase II transcription cofactor activity(GO:0001104)
0.0	0.0	GO:0050693	LBD domain binding(GO:0050693)
0.0	0.2	GO:0016846	carbon-sulfur lyase activity(GO:0016846)
0.0	0.1	GO:0030229	very-low-density lipoprotein particle receptor activity(GO:0030229)
0.0	0.2	GO:0046933	proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.0	0.1	GO:0070567	cytidylyltransferase activity(GO:0070567)
0.0	0.0	GO:0008469	histone-arginine N-methyltransferase activity(GO:0008469)
0.0	0.1	GO:0048018	receptor agonist activity(GO:0048018)
0.0	0.1	GO:0043208	glycosphingolipid binding(GO:0043208)
0.0	0.0	GO:0000268	peroxisome targeting sequence binding(GO:0000268)
0.0	0.8	GO:0004221	obsolete ubiquitin thiolesterase activity(GO:0004221)
0.0	0.1	GO:0016934	extracellular-glycine-gated ion channel activity(GO:0016933) extracellular-glycine-gated chloride channel activity(GO:0016934)
0.0	0.1	GO:0003709	obsolete RNA polymerase III transcription factor activity(GO:0003709)
0.0	0.4	GO:0017137	Rab GTPase binding(GO:0017137)
0.0	0.3	GO:0016676	cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors(GO:0016675) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0	0.0	GO:0004980	melanocyte-stimulating hormone receptor activity(GO:0004980)
0.0	0.1	GO:0030676	Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0	0.0	GO:0070095	fructose-6-phosphate binding(GO:0070095)
0.0	0.1	GO:0030515	snoRNA binding(GO:0030515)
0.0	0.1	GO:0030275	LRR domain binding(GO:0030275)
0.0	0.7	GO:0016410	N-acyltransferase activity(GO:0016410)
0.0	0.3	GO:0000149	SNARE binding(GO:0000149)
0.0	0.1	GO:0043539	protein serine/threonine kinase activator activity(GO:0043539)
0.0	0.1	GO:0070742	C2H2 zinc finger domain binding(GO:0070742)
0.0	0.1	GO:0030296	protein tyrosine kinase activator activity(GO:0030296)
0.0	0.1	GO:0004428	obsolete inositol or phosphatidylinositol kinase activity(GO:0004428)
0.0	0.0	GO:0004321	fatty-acyl-CoA synthase activity(GO:0004321)
0.0	0.2	GO:0009881	photoreceptor activity(GO:0009881)
0.0	0.1	GO:0005521	lamin binding(GO:0005521)
0.0	0.0	GO:0050265	RNA uridylyltransferase activity(GO:0050265)
0.0	0.0	GO:0016986	obsolete transcription initiation factor activity(GO:0016986)
0.0	0.0	GO:0016922	ligand-dependent nuclear receptor binding(GO:0016922)
0.0	0.0	GO:0004673	protein histidine kinase activity(GO:0004673)
0.0	0.1	GO:0070888	E-box binding(GO:0070888)
0.0	0.2	GO:0005231	excitatory extracellular ligand-gated ion channel activity(GO:0005231)
0.0	0.2	GO:0004435	phosphatidylinositol phospholipase C activity(GO:0004435)
0.0	0.3	GO:0051087	chaperone binding(GO:0051087)
0.0	0.0	GO:0004169	dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.0	2.6	GO:0030695	GTPase regulator activity(GO:0030695)
0.0	0.1	GO:0017091	AU-rich element binding(GO:0017091)
0.0	0.3	GO:0004693	cyclin-dependent protein serine/threonine kinase activity(GO:0004693) cyclin-dependent protein kinase activity(GO:0097472)
0.0	0.8	GO:0017124	SH3 domain binding(GO:0017124)
0.0	0.1	GO:0015464	acetylcholine receptor activity(GO:0015464)
0.0	0.1	GO:0005499	vitamin D binding(GO:0005499)
0.0	0.0	GO:0017056	structural constituent of nuclear pore(GO:0017056)
0.0	0.0	GO:0002054	nucleobase binding(GO:0002054)
0.0	0.0	GO:0008192	RNA guanylyltransferase activity(GO:0008192)
0.0	0.5	GO:0004725	protein tyrosine phosphatase activity(GO:0004725)
0.0	0.0	GO:0019956	chemokine binding(GO:0019956)
0.0	0.1	GO:0046912	transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
0.0	0.2	GO:0019843	rRNA binding(GO:0019843)
0.0	0.0	GO:0003918	DNA topoisomerase type II (ATP-hydrolyzing) activity(GO:0003918) DNA topoisomerase II activity(GO:0061505)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	5.6	PID CD8 TCR PATHWAY	TCR signaling in naïve CD8+ T cells
0.1	1.2	SA PTEN PATHWAY	PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.1	1.4	PID TCR PATHWAY	TCR signaling in naïve CD4+ T cells
0.1	0.1	PID S1P S1P4 PATHWAY	S1P4 pathway
0.1	1.4	PID IL2 STAT5 PATHWAY	IL2 signaling events mediated by STAT5
0.1	0.9	PID LPA4 PATHWAY	LPA4-mediated signaling events
0.1	0.3	PID TCR RAS PATHWAY	Ras signaling in the CD4+ TCR pathway
0.1	0.2	PID IL8 CXCR1 PATHWAY	IL8- and CXCR1-mediated signaling events
0.0	0.0	PID PI3KCI AKT PATHWAY	Class I PI3K signaling events mediated by Akt
0.0	0.3	SA PROGRAMMED CELL DEATH	Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.0	0.7	PID BETA CATENIN DEG PATHWAY	Degradation of beta catenin
0.0	0.6	SA MMP CYTOKINE CONNECTION	Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0	1.8	PID NFAT 3PATHWAY	Role of Calcineurin-dependent NFAT signaling in lymphocytes
0.0	0.3	SIG PIP3 SIGNALING IN B LYMPHOCYTES	Genes related to PIP3 signaling in B lymphocytes
0.0	1.3	PID ECADHERIN NASCENT AJ PATHWAY	E-cadherin signaling in the nascent adherens junction
0.0	0.0	PID CXCR3 PATHWAY	CXCR3-mediated signaling events
0.0	0.7	PID EPHRINB REV PATHWAY	Ephrin B reverse signaling
0.0	0.2	SA TRKA RECEPTOR	The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth.
0.0	0.9	PID IL8 CXCR2 PATHWAY	IL8- and CXCR2-mediated signaling events
0.0	1.1	PID PI3KCI PATHWAY	Class I PI3K signaling events
0.0	0.7	PID HDAC CLASSIII PATHWAY	Signaling events mediated by HDAC Class III
0.0	0.1	ST DIFFERENTIATION PATHWAY IN PC12 CELLS	Differentiation Pathway in PC12 Cells; this is a specific case of PAC1 Receptor Pathway.
0.0	0.1	SA FAS SIGNALING	The TNF-type receptor Fas induces apoptosis on ligand binding.
0.0	0.4	PID IL12 STAT4 PATHWAY	IL12 signaling mediated by STAT4
0.0	1.0	PID NFAT TFPATHWAY	Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0	0.2	PID PRL SIGNALING EVENTS PATHWAY	Signaling events mediated by PRL
0.0	0.3	SA REG CASCADE OF CYCLIN EXPR	Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.0	0.4	PID P38 ALPHA BETA PATHWAY	Regulation of p38-alpha and p38-beta
0.0	1.5	PID BETA CATENIN NUC PATHWAY	Regulation of nuclear beta catenin signaling and target gene transcription
0.0	0.2	PID GMCSF PATHWAY	GMCSF-mediated signaling events
0.0	0.5	PID BCR 5PATHWAY	BCR signaling pathway
0.0	0.6	PID KIT PATHWAY	Signaling events mediated by Stem cell factor receptor (c-Kit)
0.0	0.6	PID THROMBIN PAR1 PATHWAY	PAR1-mediated thrombin signaling events
0.0	0.3	PID P38 MK2 PATHWAY	p38 signaling mediated by MAPKAP kinases
0.0	0.5	PID CD8 TCR DOWNSTREAM PATHWAY	Downstream signaling in naïve CD8+ T cells
0.0	0.5	PID ERBB1 INTERNALIZATION PATHWAY	Internalization of ErbB1
0.0	0.7	PID CERAMIDE PATHWAY	Ceramide signaling pathway
0.0	0.6	PID INTEGRIN CS PATHWAY	Integrin family cell surface interactions
0.0	0.5	PID CDC42 REG PATHWAY	Regulation of CDC42 activity
0.0	0.0	PID SYNDECAN 1 PATHWAY	Syndecan-1-mediated signaling events
0.0	0.3	PID TXA2PATHWAY	Thromboxane A2 receptor signaling
0.0	0.1	ST IL 13 PATHWAY	Interleukin 13 (IL-13) Pathway
0.0	0.2	PID CD40 PATHWAY	CD40/CD40L signaling
0.0	0.4	PID HIF2PATHWAY	HIF-2-alpha transcription factor network
0.0	0.3	SIG BCR SIGNALING PATHWAY	Members of the BCR signaling pathway
0.0	0.1	PID RANBP2 PATHWAY	Sumoylation by RanBP2 regulates transcriptional repression
0.0	0.4	PID IL12 2PATHWAY	IL12-mediated signaling events
0.0	0.2	PID WNT CANONICAL PATHWAY	Canonical Wnt signaling pathway
0.0	0.1	PID IL27 PATHWAY	IL27-mediated signaling events
0.0	0.2	PID DNA PK PATHWAY	DNA-PK pathway in nonhomologous end joining
0.0	0.1	PID NFKAPPAB CANONICAL PATHWAY	Canonical NF-kappaB pathway
0.0	0.3	PID RAS PATHWAY	Regulation of Ras family activation
0.0	0.3	PID HEDGEHOG GLI PATHWAY	Hedgehog signaling events mediated by Gli proteins
0.0	0.1	PID IL2 1PATHWAY	IL2-mediated signaling events
0.0	0.1	PID IL6 7 PATHWAY	IL6-mediated signaling events
0.0	0.5	PID AR TF PATHWAY	Regulation of Androgen receptor activity
0.0	0.4	PID LKB1 PATHWAY	LKB1 signaling events
0.0	0.1	PID ANTHRAX PATHWAY	Cellular roles of Anthrax toxin
0.0	0.1	PID IL23 PATHWAY	IL23-mediated signaling events
0.0	0.2	PID INSULIN GLUCOSE PATHWAY	Insulin-mediated glucose transport
0.0	0.7	PID SMAD2 3NUCLEAR PATHWAY	Regulation of nuclear SMAD2/3 signaling
0.0	0.0	PID IL5 PATHWAY	IL5-mediated signaling events
0.0	0.5	PID ERA GENOMIC PATHWAY	Validated nuclear estrogen receptor alpha network
0.0	0.3	PID TELOMERASE PATHWAY	Regulation of Telomerase
0.0	0.2	PID RB 1PATHWAY	Regulation of retinoblastoma protein
0.0	0.0	PID EPHA2 FWD PATHWAY	EPHA2 forward signaling
0.0	0.1	PID MYC PATHWAY	C-MYC pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	0.8	REACTOME BINDING AND ENTRY OF HIV VIRION	Genes involved in Binding and entry of HIV virion
0.2	0.6	REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS	Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.1	1.3	REACTOME PECAM1 INTERACTIONS	Genes involved in PECAM1 interactions
0.1	0.5	REACTOME DAG AND IP3 SIGNALING	Genes involved in DAG and IP3 signaling
0.1	2.3	REACTOME GENERATION OF SECOND MESSENGER MOLECULES	Genes involved in Generation of second messenger molecules
0.1	2.2	REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS	Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.1	2.1	REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE	Genes involved in Sema4D induced cell migration and growth-cone collapse
0.1	0.1	REACTOME PROSTACYCLIN SIGNALLING THROUGH PROSTACYCLIN RECEPTOR	Genes involved in Prostacyclin signalling through prostacyclin receptor
0.1	0.7	REACTOME IL 7 SIGNALING	Genes involved in Interleukin-7 signaling
0.1	0.6	REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY	Genes involved in Adenylate cyclase activating pathway
0.1	0.5	REACTOME PKA MEDIATED PHOSPHORYLATION OF CREB	Genes involved in PKA-mediated phosphorylation of CREB
0.1	0.3	REACTOME COSTIMULATION BY THE CD28 FAMILY	Genes involved in Costimulation by the CD28 family
0.1	0.9	REACTOME G ALPHA Z SIGNALLING EVENTS	Genes involved in G alpha (z) signalling events
0.1	0.2	REACTOME EGFR DOWNREGULATION	Genes involved in EGFR downregulation
0.0	0.0	REACTOME ENDOSOMAL VACUOLAR PATHWAY	Genes involved in Endosomal/Vacuolar pathway
0.0	0.2	REACTOME IRAK1 RECRUITS IKK COMPLEX	Genes involved in IRAK1 recruits IKK complex
0.0	0.1	REACTOME REGULATION OF SIGNALING BY CBL	Genes involved in Regulation of signaling by CBL
0.0	0.5	REACTOME THE NLRP3 INFLAMMASOME	Genes involved in The NLRP3 inflammasome
0.0	1.1	REACTOME G BETA GAMMA SIGNALLING THROUGH PI3KGAMMA	Genes involved in G beta:gamma signalling through PI3Kgamma
0.0	0.6	REACTOME N GLYCAN ANTENNAE ELONGATION	Genes involved in N-Glycan antennae elongation
0.0	0.5	REACTOME PROLACTIN RECEPTOR SIGNALING	Genes involved in Prolactin receptor signaling
0.0	1.1	REACTOME IL 2 SIGNALING	Genes involved in Interleukin-2 signaling
0.0	0.9	REACTOME THE ROLE OF NEF IN HIV1 REPLICATION AND DISEASE PATHOGENESIS	Genes involved in The role of Nef in HIV-1 replication and disease pathogenesis
0.0	0.1	REACTOME PD1 SIGNALING	Genes involved in PD-1 signaling
0.0	0.7	REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION	Genes involved in GABA synthesis, release, reuptake and degradation
0.0	0.2	REACTOME INFLAMMASOMES	Genes involved in Inflammasomes
0.0	0.5	REACTOME PURINE SALVAGE	Genes involved in Purine salvage
0.0	0.4	REACTOME RAP1 SIGNALLING	Genes involved in Rap1 signalling
0.0	0.3	REACTOME ACTIVATION OF RAC	Genes involved in Activation of Rac
0.0	0.2	REACTOME IL 6 SIGNALING	Genes involved in Interleukin-6 signaling
0.0	1.9	REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL	Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0	0.2	REACTOME SPRY REGULATION OF FGF SIGNALING	Genes involved in Spry regulation of FGF signaling
0.0	0.4	REACTOME HIGHLY CALCIUM PERMEABLE POSTSYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS	Genes involved in Highly calcium permeable postsynaptic nicotinic acetylcholine receptors
0.0	0.2	REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY	Genes involved in Regulation of the Fanconi anemia pathway
0.0	0.4	REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR	Genes involved in Trafficking and processing of endosomal TLR
0.0	0.3	REACTOME TAK1 ACTIVATES NFKB BY PHOSPHORYLATION AND ACTIVATION OF IKKS COMPLEX	Genes involved in TAK1 activates NFkB by phosphorylation and activation of IKKs complex
0.0	0.2	REACTOME CTLA4 INHIBITORY SIGNALING	Genes involved in CTLA4 inhibitory signaling
0.0	0.4	REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS	Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.0	0.3	REACTOME DARPP 32 EVENTS	Genes involved in DARPP-32 events
0.0	0.5	REACTOME NUCLEOTIDE LIKE PURINERGIC RECEPTORS	Genes involved in Nucleotide-like (purinergic) receptors
0.0	0.0	REACTOME INFLUENZA LIFE CYCLE	Genes involved in Influenza Life Cycle
0.0	0.1	REACTOME REGULATION OF INSULIN SECRETION BY GLUCAGON LIKE PEPTIDE1	Genes involved in Regulation of Insulin Secretion by Glucagon-like Peptide-1
0.0	0.1	REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS	Genes involved in Elevation of cytosolic Ca2+ levels
0.0	0.6	REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE	Genes involved in Synthesis of PIPs at the plasma membrane
0.0	0.2	REACTOME REGULATION OF KIT SIGNALING	Genes involved in Regulation of KIT signaling
0.0	0.5	REACTOME TRANSPORT TO THE GOLGI AND SUBSEQUENT MODIFICATION	Genes involved in Transport to the Golgi and subsequent modification
0.0	0.4	REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS	Genes involved in Synthesis of substrates in N-glycan biosythesis
0.0	0.3	REACTOME OPSINS	Genes involved in Opsins
0.0	0.0	REACTOME SCF BETA TRCP MEDIATED DEGRADATION OF EMI1	Genes involved in SCF-beta-TrCP mediated degradation of Emi1
0.0	1.4	REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES	Genes involved in Chemokine receptors bind chemokines
0.0	0.2	REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE	Genes involved in Glutamate Neurotransmitter Release Cycle
0.0	0.5	REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY	Genes involved in Post-chaperonin tubulin folding pathway
0.0	0.7	REACTOME TRANSPORT OF RIBONUCLEOPROTEINS INTO THE HOST NUCLEUS	Genes involved in Transport of Ribonucleoproteins into the Host Nucleus
0.0	0.3	REACTOME ASSOCIATION OF LICENSING FACTORS WITH THE PRE REPLICATIVE COMPLEX	Genes involved in Association of licensing factors with the pre-replicative complex
0.0	1.0	REACTOME GLYCOSPHINGOLIPID METABOLISM	Genes involved in Glycosphingolipid metabolism
0.0	0.4	REACTOME ENOS ACTIVATION AND REGULATION	Genes involved in eNOS activation and regulation
0.0	0.5	REACTOME PRE NOTCH TRANSCRIPTION AND TRANSLATION	Genes involved in Pre-NOTCH Transcription and Translation
0.0	2.0	REACTOME RESPIRATORY ELECTRON TRANSPORT ATP SYNTHESIS BY CHEMIOSMOTIC COUPLING AND HEAT PRODUCTION BY UNCOUPLING PROTEINS	Genes involved in Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins.
0.0	0.1	REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX UPON TLR7 8 OR 9 STIMULATION	Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
0.0	0.1	REACTOME PHOSPHOLIPASE C MEDIATED CASCADE	Genes involved in Phospholipase C-mediated cascade
0.0	0.2	REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP	Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.0	0.7	REACTOME SIGNALING BY SCF KIT	Genes involved in Signaling by SCF-KIT
0.0	0.2	REACTOME DSCAM INTERACTIONS	Genes involved in DSCAM interactions
0.0	1.0	REACTOME VOLTAGE GATED POTASSIUM CHANNELS	Genes involved in Voltage gated Potassium channels
0.0	0.8	REACTOME G ALPHA1213 SIGNALLING EVENTS	Genes involved in G alpha (12/13) signalling events
0.0	0.1	REACTOME SCFSKP2 MEDIATED DEGRADATION OF P27 P21	Genes involved in SCF(Skp2)-mediated degradation of p27/p21
0.0	0.2	REACTOME PROSTANOID LIGAND RECEPTORS	Genes involved in Prostanoid ligand receptors
0.0	0.3	REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN	Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.0	0.3	REACTOME CREB PHOSPHORYLATION THROUGH THE ACTIVATION OF RAS	Genes involved in CREB phosphorylation through the activation of Ras
0.0	0.8	REACTOME INTERFERON GAMMA SIGNALING	Genes involved in Interferon gamma signaling
0.0	0.2	REACTOME DOWNSTREAM TCR SIGNALING	Genes involved in Downstream TCR signaling
0.0	0.4	REACTOME G1 PHASE	Genes involved in G1 Phase
0.0	0.4	REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS	Genes involved in Termination of O-glycan biosynthesis
0.0	0.4	REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS	Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.0	0.3	REACTOME INTRINSIC PATHWAY FOR APOPTOSIS	Genes involved in Intrinsic Pathway for Apoptosis
0.0	0.2	REACTOME REGULATION OF COMPLEMENT CASCADE	Genes involved in Regulation of Complement cascade
0.0	0.8	REACTOME VIF MEDIATED DEGRADATION OF APOBEC3G	Genes involved in Vif-mediated degradation of APOBEC3G
0.0	0.1	REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS	Genes involved in Membrane binding and targetting of GAG proteins
0.0	0.1	REACTOME P38MAPK EVENTS	Genes involved in p38MAPK events
0.0	0.3	REACTOME CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE	Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
0.0	0.1	REACTOME TRAF6 MEDIATED NFKB ACTIVATION	Genes involved in TRAF6 mediated NF-kB activation
0.0	0.6	REACTOME ION TRANSPORT BY P TYPE ATPASES	Genes involved in Ion transport by P-type ATPases
0.0	0.0	REACTOME MITOTIC M M G1 PHASES	Genes involved in Mitotic M-M/G1 phases
0.0	0.4	REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING	Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.0	0.3	REACTOME CHONDROITIN SULFATE BIOSYNTHESIS	Genes involved in Chondroitin sulfate biosynthesis
0.0	0.2	REACTOME VIRAL MESSENGER RNA SYNTHESIS	Genes involved in Viral Messenger RNA Synthesis
0.0	0.1	REACTOME COMMON PATHWAY	Genes involved in Common Pathway
0.0	0.2	REACTOME CITRIC ACID CYCLE TCA CYCLE	Genes involved in Citric acid cycle (TCA cycle)
0.0	0.6	REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S	Genes involved in Activation of Chaperone Genes by XBP1(S)
0.0	0.1	REACTOME ABORTIVE ELONGATION OF HIV1 TRANSCRIPT IN THE ABSENCE OF TAT	Genes involved in Abortive elongation of HIV-1 transcript in the absence of Tat
0.0	1.0	REACTOME SIGNALING BY RHO GTPASES	Genes involved in Signaling by Rho GTPases
0.0	0.0	REACTOME ARMS MEDIATED ACTIVATION	Genes involved in ARMS-mediated activation
0.0	0.2	REACTOME SYNTHESIS OF PE	Genes involved in Synthesis of PE
0.0	0.2	REACTOME METABOLISM OF PORPHYRINS	Genes involved in Metabolism of porphyrins
0.0	0.0	REACTOME POST NMDA RECEPTOR ACTIVATION EVENTS	Genes involved in Post NMDA receptor activation events
0.0	0.0	REACTOME DESTABILIZATION OF MRNA BY KSRP	Genes involved in Destabilization of mRNA by KSRP
0.0	0.1	REACTOME SIGNALING BY ROBO RECEPTOR	Genes involved in Signaling by Robo receptor
0.0	0.0	REACTOME CYCLIN E ASSOCIATED EVENTS DURING G1 S TRANSITION	Genes involved in Cyclin E associated events during G1/S transition
0.0	0.3	REACTOME REGULATION OF BETA CELL DEVELOPMENT	Genes involved in Regulation of beta-cell development
0.0	0.2	REACTOME ZINC TRANSPORTERS	Genes involved in Zinc transporters
0.0	0.0	REACTOME G2 M DNA DAMAGE CHECKPOINT	Genes involved in G2/M DNA damage checkpoint
0.0	0.0	REACTOME DESTABILIZATION OF MRNA BY AUF1 HNRNP D0	Genes involved in Destabilization of mRNA by AUF1 (hnRNP D0)
0.0	0.3	REACTOME REGULATION OF INSULIN SECRETION	Genes involved in Regulation of Insulin Secretion
0.0	0.3	REACTOME CHOLESTEROL BIOSYNTHESIS	Genes involved in Cholesterol biosynthesis
0.0	0.2	REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION	Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.0	0.1	REACTOME ABACAVIR TRANSPORT AND METABOLISM	Genes involved in Abacavir transport and metabolism
0.0	0.2	REACTOME PYRUVATE METABOLISM	Genes involved in Pyruvate metabolism
0.0	0.0	REACTOME PEPTIDE CHAIN ELONGATION	Genes involved in Peptide chain elongation
0.0	0.0	REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS	Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
0.0	0.1	REACTOME MRNA CAPPING	Genes involved in mRNA Capping
0.0	0.1	REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING	Genes involved in Downregulation of TGF-beta receptor signaling
0.0	0.1	REACTOME NONSENSE MEDIATED DECAY ENHANCED BY THE EXON JUNCTION COMPLEX	Genes involved in Nonsense Mediated Decay Enhanced by the Exon Junction Complex
0.0	0.1	REACTOME G0 AND EARLY G1	Genes involved in G0 and Early G1
0.0	0.2	REACTOME CGMP EFFECTS	Genes involved in cGMP effects
0.0	0.4	REACTOME MITOCHONDRIAL PROTEIN IMPORT	Genes involved in Mitochondrial Protein Import
0.0	0.2	REACTOME BOTULINUM NEUROTOXICITY	Genes involved in Botulinum neurotoxicity
0.0	0.2	REACTOME ENERGY DEPENDENT REGULATION OF MTOR BY LKB1 AMPK	Genes involved in Energy dependent regulation of mTOR by LKB1-AMPK
0.0	0.1	REACTOME SEROTONIN RECEPTORS	Genes involved in Serotonin receptors
0.0	0.3	REACTOME EXTENSION OF TELOMERES	Genes involved in Extension of Telomeres
0.0	0.3	REACTOME O LINKED GLYCOSYLATION OF MUCINS	Genes involved in O-linked glycosylation of mucins
0.0	0.2	REACTOME METABOLISM OF NON CODING RNA	Genes involved in Metabolism of non-coding RNA
0.0	0.0	REACTOME PHOSPHORYLATION OF THE APC C	Genes involved in Phosphorylation of the APC/C

Results for PPARG

Z-value: 1.79

Motif logo

Transcription factors associated with PPARG

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

Activity of the PPARG motif across conditions

Conditions sorted by the z-value of the PPARG motif activity

Top target CREs of the motif:

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of PPARG

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category:

Gene overrepresentation in curated gene sets: canonical pathways category:

Gene overrepresentation in curated gene sets: REACTOME pathways category: