Project
ENCODE: H3K4me1 ChIP-Seq of primary human cells
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CREMA is a free online tool that recognizes most important transcription factors that change the chromatin state across different samples.

Results for PPARG

Z-value: 1.79

Motif logo

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Transcription factors associated with PPARG

Gene Symbol Gene ID Gene Info
ENSG00000132170.15 PPARG

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE Gene Distance Association probability Pearson corr. coef. P-value Plot
PPARGchr3_12395833_1239598429370.349675-0.933.1e-04Click!
PPARGchr3_12266121_12266272626710.122427-0.826.6e-03Click!
PPARGchr3_12377941_12378223148890.2561900.742.4e-02Click!
PPARGchr3_12422682_12422833297860.1968600.732.5e-02Click!
PPARGchr3_12276997_12277148517950.150660-0.722.8e-02Click!

Activity of the PPARG motif across conditions

Conditions sorted by the z-value of the PPARG motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE) Target Score Top associated gene Gene Info Distance of CRE to TSS CRE/Gene association probability
chr7_99819712_99820188 1.09 ENSG00000222482
.
2207
0.15
chr3_187696515_187696882 1.07 LPP
LIM domain containing preferred translocation partner in lipoma
174374
0.03
chr7_148981019_148981379 0.86 ZNF783
zinc finger family member 783
1203
0.36
chr7_2739468_2739742 0.75 AMZ1
archaelysin family metallopeptidase 1
11769
0.21
chr1_202132763_202133787 0.72 PTPN7
protein tyrosine phosphatase, non-receptor type 7
2559
0.21
chr11_65408846_65409255 0.70 SIPA1
signal-induced proliferation-associated 1
751
0.41
chr19_49838163_49838543 0.66 CD37
CD37 molecule
300
0.78
chr11_6424420_6425308 0.66 APBB1
amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65)
1030
0.44
chr9_137367972_137368123 0.66 RXRA
retinoid X receptor, alpha
69619
0.11
chr16_57168390_57168643 0.61 CPNE2
copine II
15405
0.14
chr14_98676295_98676520 0.58 ENSG00000222066
.
121680
0.06
chr14_100546662_100546850 0.58 CTD-2376I20.1

5541
0.16
chr16_79313034_79313388 0.57 ENSG00000222244
.
14860
0.29
chr11_12378207_12378574 0.57 ENSG00000264283
.
12076
0.19
chr16_88545798_88545998 0.56 ENSG00000263456
.
10572
0.17
chr11_121351250_121351763 0.56 RP11-730K11.1

27784
0.21
chr12_133064825_133065258 0.55 FBRSL1
fibrosin-like 1
1096
0.54
chr16_50308946_50309418 0.55 ADCY7
adenylate cyclase 7
1118
0.53
chr12_113527618_113527818 0.54 DTX1
deltex homolog 1 (Drosophila)
32223
0.11
chr21_32549988_32550321 0.54 TIAM1
T-cell lymphoma invasion and metastasis 1
47615
0.18
chr11_73716797_73717380 0.53 UCP3
uncoupling protein 3 (mitochondrial, proton carrier)
1261
0.4
chr3_33095798_33096165 0.53 GLB1
galactosidase, beta 1
42303
0.12
chr3_33094206_33094581 0.53 GLB1
galactosidase, beta 1
43891
0.12
chrX_152603368_152603519 0.52 ZNF275
zinc finger protein 275
3830
0.2
chr10_15227195_15227346 0.52 NMT2
N-myristoyltransferase 2
16578
0.2
chr10_6571440_6571602 0.52 PRKCQ
protein kinase C, theta
50680
0.18
chr1_206755327_206755741 0.52 RASSF5
Ras association (RalGDS/AF-6) domain family member 5
25041
0.13
chr22_45016760_45017091 0.51 PRR5
proline rich 5 (renal)
47668
0.15
chr3_14924290_14924594 0.51 FGD5
FYVE, RhoGEF and PH domain containing 5
61503
0.1
chr8_81289205_81289813 0.51 ENSG00000252884
.
28242
0.19
chr17_38762219_38762396 0.51 SMARCE1
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 1
26235
0.12
chr17_72751609_72751889 0.51 SLC9A3R1
solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 1
6393
0.1
chr6_167533760_167534243 0.50 CCR6
chemokine (C-C motif) receptor 6
2256
0.3
chr3_177360373_177360796 0.50 ENSG00000200288
.
18387
0.29
chr20_57723964_57724434 0.50 ZNF831
zinc finger protein 831
41876
0.16
chr17_76128893_76129294 0.50 TMC6
transmembrane channel-like 6
605
0.58
chr2_122496335_122496524 0.50 TSN
translin
1750
0.3
chr11_1781297_1781822 0.49 AC068580.6

19
0.92
chr20_39775264_39775450 0.49 RP1-1J6.2

8714
0.2
chr14_106453805_106454306 0.49 IGHV1-2
immunoglobulin heavy variable 1-2
885
0.24
chr19_17112962_17113366 0.49 CTD-2528A14.1

6835
0.15
chr5_133467358_133467605 0.49 TCF7
transcription factor 7 (T-cell specific, HMG-box)
8172
0.21
chr20_31123380_31123862 0.49 C20orf112
chromosome 20 open reading frame 112
579
0.74
chr7_2739159_2739434 0.48 AMZ1
archaelysin family metallopeptidase 1
11460
0.21
chr3_15503071_15503367 0.48 EAF1-AS1
EAF1 antisense RNA 1
10110
0.12
chr19_49902085_49902258 0.48 CCDC155
coiled-coil domain containing 155
4371
0.08
chr14_61850578_61851088 0.48 PRKCH
protein kinase C, eta
6579
0.26
chr7_8171333_8171763 0.48 AC006042.6

17893
0.2
chr2_113944916_113945243 0.47 PSD4
pleckstrin and Sec7 domain containing 4
8778
0.14
chr11_67173408_67173659 0.47 TBC1D10C
TBC1 domain family, member 10C
1873
0.13
chr5_35852211_35852414 0.47 IL7R
interleukin 7 receptor
485
0.82
chr10_3462118_3462297 0.47 PITRM1
pitrilysin metallopeptidase 1
247204
0.02
chr10_29969072_29969239 0.47 ENSG00000222092
.
31689
0.18
chr19_51627416_51627752 0.47 SIGLEC9
sialic acid binding Ig-like lectin 9
581
0.56
chr5_156644403_156644620 0.47 CTB-4E7.1

6879
0.14
chr1_160535323_160535488 0.47 CD84
CD84 molecule
13858
0.13
chr22_18258720_18259014 0.46 BID
BH3 interacting domain death agonist
1436
0.41
chr3_46390356_46390605 0.46 CCR2
chemokine (C-C motif) receptor 2
4745
0.2
chr22_37543853_37544124 0.46 IL2RB
interleukin 2 receptor, beta
2042
0.21
chr1_25252459_25252702 0.46 RUNX3
runt-related transcription factor 3
3032
0.3
chr5_1313612_1313923 0.46 ENSG00000263670
.
4275
0.2
chr12_121473450_121473650 0.46 OASL
2'-5'-oligoadenylate synthetase-like
3200
0.19
chr4_40218742_40218915 0.45 RHOH
ras homolog family member H
16864
0.21
chr22_27040168_27040347 0.45 CRYBA4
crystallin, beta A4
22329
0.17
chr10_73863981_73864132 0.45 SPOCK2
sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2
15266
0.2
chr6_33873520_33874114 0.45 ENSG00000221697
.
94011
0.06
chr20_43277539_43277694 0.45 ADA
adenosine deaminase
2716
0.2
chr21_46338509_46338732 0.44 ITGB2
integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
2150
0.17
chr19_16467370_16467664 0.44 EPS15L1
epidermal growth factor receptor pathway substrate 15-like 1
5247
0.16
chr17_999891_1000162 0.44 ABR
active BCR-related
12314
0.2
chr6_5522387_5522696 0.44 RP1-232P20.1

64233
0.14
chr1_207090489_207090800 0.44 FAIM3
Fas apoptotic inhibitory molecule 3
4568
0.17
chr14_101106211_101106459 0.44 CTD-2644I21.1

50672
0.08
chr7_149565914_149566574 0.44 ATP6V0E2
ATPase, H+ transporting V0 subunit e2
3813
0.19
chr5_175956521_175957004 0.44 RNF44
ring finger protein 44
884
0.47
chr3_46416206_46416357 0.44 CCR5
chemokine (C-C motif) receptor 5 (gene/pseudogene)
2120
0.26
chr8_134067708_134067917 0.43 SLA
Src-like-adaptor
4791
0.28
chr1_154238433_154238584 0.43 ENSG00000201129
.
6305
0.08
chr10_4170376_4170710 0.43 KLF6
Kruppel-like factor 6
343070
0.01
chr7_148325963_148326351 0.43 C7orf33
chromosome 7 open reading frame 33
38500
0.16
chr5_110564408_110564849 0.43 CAMK4
calcium/calmodulin-dependent protein kinase IV
4844
0.26
chr7_38407986_38408314 0.43 AMPH
amphiphysin
94563
0.09
chr16_30392632_30392982 0.43 SEPT1
septin 1
945
0.31
chr14_22974081_22974308 0.43 TRAJ51
T cell receptor alpha joining 51 (pseudogene)
18023
0.09
chr9_132345350_132345729 0.43 RP11-492E3.2

7851
0.14
chr9_130623880_130624317 0.43 ENG
endoglin
7063
0.08
chr9_95834544_95834805 0.42 SUSD3
sushi domain containing 3
3292
0.21
chr1_158899632_158899783 0.42 PYHIN1
pyrin and HIN domain family, member 1
879
0.64
chr4_1237782_1238175 0.42 CTBP1
C-terminal binding protein 1
2267
0.22
chr1_25248232_25248398 0.42 RUNX3
runt-related transcription factor 3
7297
0.24
chr17_47814433_47814907 0.42 FAM117A
family with sequence similarity 117, member A
12781
0.14
chr3_46005175_46005371 0.42 FYCO1
FYVE and coiled-coil domain containing 1
5120
0.19
chr14_91858369_91858695 0.42 CCDC88C
coiled-coil domain containing 88C
25158
0.2
chr15_32651213_32651761 0.42 ENSG00000221444
.
34186
0.1
chr2_235334226_235334544 0.42 ARL4C
ADP-ribosylation factor-like 4C
70859
0.14
chr8_125575470_125576116 0.42 MTSS1
metastasis suppressor 1
2175
0.26
chr22_23268788_23268939 0.42 IGLJ7
immunoglobulin lambda joining 7
5301
0.07
chr16_57163028_57163387 0.42 CPNE2
copine II
10096
0.15
chr1_207633000_207633151 0.42 CR2
complement component (3d/Epstein Barr virus) receptor 2
5365
0.23
chr17_39496825_39497026 0.42 KRT33A
keratin 33A
10139
0.08
chr2_102984737_102985012 0.41 IL18R1
interleukin 18 receptor 1
5753
0.19
chr8_125574992_125575143 0.41 MTSS1
metastasis suppressor 1
2901
0.21
chr19_16228666_16229162 0.41 RAB8A
RAB8A, member RAS oncogene family
6207
0.14
chr3_46411260_46411477 0.41 CCR5
chemokine (C-C motif) receptor 5 (gene/pseudogene)
265
0.9
chr2_28572176_28572390 0.41 AC093690.1

38957
0.13
chr1_9778118_9778444 0.41 PIK3CD
phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta
154
0.95
chr14_22565547_22565859 0.41 ENSG00000238634
.
45184
0.18
chr20_2723372_2723744 0.41 EBF4
early B-cell factor 4
36671
0.09
chr2_241503761_241504027 0.40 RNPEPL1
arginyl aminopeptidase (aminopeptidase B)-like 1
1327
0.3
chr16_68403491_68403775 0.40 SMPD3
sphingomyelin phosphodiesterase 3, neutral membrane (neutral sphingomyelinase II)
1275
0.35
chr17_37252182_37252943 0.40 PLXDC1
plexin domain containing 1
11178
0.15
chr14_21136496_21136717 0.40 ENSG00000199461
.
10964
0.09
chr6_160436305_160436759 0.40 AIRN
antisense of IGF2R non-protein coding RNA
7836
0.24
chr1_59407152_59407509 0.40 JUN
jun proto-oncogene
157545
0.04
chr17_81146535_81146986 0.40 METRNL
meteorin, glial cell differentiation regulator-like
94766
0.08
chr9_134143505_134143979 0.40 FAM78A
family with sequence similarity 78, member A
2138
0.29
chr4_40305683_40306008 0.40 CHRNA9
cholinergic receptor, nicotinic, alpha 9 (neuronal)
31501
0.18
chr4_40219694_40220159 0.40 RHOH
ras homolog family member H
17962
0.21
chr1_25253582_25253853 0.40 RUNX3
runt-related transcription factor 3
1895
0.39
chr6_112114827_112115099 0.39 FYN
FYN oncogene related to SRC, FGR, YES
126
0.98
chr1_776644_776929 0.39 RP11-206L10.8

31245
0.11
chr6_159519924_159520304 0.39 TAGAP
T-cell activation RhoGTPase activating protein
53930
0.11
chr19_42377110_42377408 0.39 CD79A
CD79a molecule, immunoglobulin-associated alpha
3931
0.13
chr17_46498324_46498623 0.39 SKAP1
src kinase associated phosphoprotein 1
9079
0.14
chr16_89762947_89763492 0.39 SPATA2L
spermatogenesis associated 2-like
4829
0.1
chr11_46352086_46352730 0.39 DGKZ
diacylglycerol kinase, zeta
2047
0.27
chr19_13213848_13214497 0.39 LYL1
lymphoblastic leukemia derived sequence 1
197
0.89
chr7_150359146_150359387 0.39 GIMAP2
GTPase, IMAP family member 2
23522
0.15
chr22_36684429_36684580 0.39 ENSG00000266345
.
27742
0.14
chr1_27165220_27165588 0.39 ZDHHC18
zinc finger, DHHC-type containing 18
6893
0.12
chr14_99450232_99450383 0.39 AL162151.4

174446
0.03
chr2_197048030_197048186 0.39 STK17B
serine/threonine kinase 17b
6881
0.2
chr1_228072467_228072618 0.39 ENSG00000264483
.
56842
0.1
chr2_74248551_74248821 0.38 TET3
tet methylcytosine dioxygenase 3
18846
0.16
chr17_35085631_35085782 0.38 MRM1
mitochondrial rRNA methyltransferase 1 homolog (S. cerevisiae)
127315
0.04
chr10_26768891_26769074 0.38 ENSG00000199733
.
29536
0.21
chr15_70550046_70550380 0.38 ENSG00000200216
.
64638
0.14
chr9_4596090_4596285 0.38 SLC1A1
solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1
23852
0.19
chrX_128904932_128905357 0.38 SASH3
SAM and SH3 domain containing 3
8816
0.2
chr1_54946013_54946309 0.38 ENSG00000265404
.
24180
0.16
chr11_119235370_119235524 0.38 USP2
ubiquitin specific peptidase 2
530
0.59
chr16_31707620_31707947 0.38 CLUHP3
clustered mitochondria (cluA/CLU1) homolog pseudogene 3
6706
0.17
chr3_68135261_68135467 0.38 FAM19A1
family with sequence similarity 19 (chemokine (C-C motif)-like), member A1
79991
0.12
chr6_149381041_149381264 0.38 RP11-162J8.3

27443
0.22
chr20_25022537_25022783 0.38 ACSS1
acyl-CoA synthetase short-chain family member 1
9321
0.2
chr11_60877401_60877552 0.38 CD5
CD5 molecule
7495
0.18
chr2_47173162_47173468 0.38 MCFD2
multiple coagulation factor deficiency 2
4321
0.17
chr14_22947374_22947525 0.38 TRAJ60
T cell receptor alpha joining 60 (pseudogene)
2153
0.16
chr2_74258310_74258513 0.38 TET3
tet methylcytosine dioxygenase 3
15039
0.17
chr2_233950353_233950744 0.38 INPP5D
inositol polyphosphate-5-phosphatase, 145kDa
25359
0.17
chr18_29563540_29563829 0.38 RNF125
ring finger protein 125, E3 ubiquitin protein ligase
34651
0.11
chr6_35279762_35280244 0.37 DEF6
differentially expressed in FDCP 6 homolog (mouse)
2488
0.27
chr2_68961132_68961308 0.37 ARHGAP25
Rho GTPase activating protein 25
693
0.77
chr20_57758094_57758324 0.37 ZNF831
zinc finger protein 831
7866
0.26
chr10_71318212_71318363 0.37 NEUROG3
neurogenin 3
14707
0.18
chrX_153582032_153582208 0.37 FLNA
filamin A, alpha
583
0.57
chr1_11802035_11802206 0.37 AGTRAP
angiotensin II receptor-associated protein
5888
0.13
chr16_3857767_3857985 0.37 CREBBP
CREB binding protein
27008
0.19
chr12_674006_674157 0.37 RP5-1154L15.2

21571
0.13
chr16_57021435_57021712 0.37 NLRC5
NLR family, CARD domain containing 5
1837
0.25
chr14_98637898_98638078 0.37 ENSG00000222066
.
160099
0.04
chr1_20015357_20015517 0.37 HTR6
5-hydroxytryptamine (serotonin) receptor 6, G protein-coupled
23657
0.16
chr12_40023753_40023976 0.37 C12orf40
chromosome 12 open reading frame 40
3879
0.28
chr10_121297891_121298084 0.37 RGS10
regulator of G-protein signaling 10
1942
0.4
chr18_2967412_2967563 0.37 RP11-737O24.1

471
0.77
chr9_140347294_140347548 0.37 NSMF
NMDA receptor synaptonuclear signaling and neuronal migration factor
1523
0.27
chr18_68307691_68307842 0.37 GTSCR1
Gilles de la Tourette syndrome chromosome region, candidate 1
10181
0.31
chr3_56952065_56952464 0.37 ARHGEF3
Rho guanine nucleotide exchange factor (GEF) 3
1765
0.42
chr10_89953557_89953785 0.37 ENSG00000200891
.
199219
0.03
chr9_70938018_70938169 0.37 FOXD4L3
forkhead box D4-like 3
20817
0.15
chr9_35910713_35911016 0.37 HRCT1
histidine rich carboxyl terminus 1
4675
0.15
chr2_106478965_106479116 0.37 AC009505.2

5407
0.26
chr10_6079510_6080013 0.36 IL2RA
interleukin 2 receptor, alpha
11797
0.14
chr9_96030770_96030921 0.36 WNK2
WNK lysine deficient protein kinase 2
4615
0.26
chr1_27160442_27160760 0.36 ZDHHC18
zinc finger, DHHC-type containing 18
2090
0.2
chr10_43790753_43790904 0.36 RASGEF1A
RasGEF domain family, member 1A
28461
0.17
chr10_9137729_9137996 0.36 ENSG00000212505
.
439068
0.01
chr16_89041472_89041726 0.36 CBFA2T3
core-binding factor, runt domain, alpha subunit 2; translocated to, 3
1802
0.3
chr12_3857026_3857275 0.36 EFCAB4B
EF-hand calcium binding domain 4B
5113
0.26
chr17_9372400_9372551 0.36 RP11-565F19.4

4416
0.22
chr11_722284_722581 0.36 AP006621.9

4615
0.09
chr1_27072713_27073114 0.36 ARID1A
AT rich interactive domain 1A (SWI-like)
17042
0.12
chr1_111179224_111179419 0.36 KCNA2
potassium voltage-gated channel, shaker-related subfamily, member 2
5225
0.2
chr11_4113400_4113717 0.36 RRM1
ribonucleotide reductase M1
2481
0.29
chr4_2817440_2817610 0.36 SH3BP2
SH3-domain binding protein 2
2387
0.3
chr11_73715681_73716026 0.36 UCP3
uncoupling protein 3 (mitochondrial, proton carrier)
2496
0.23
chr10_51503497_51503779 0.36 AGAP7
ArfGAP with GTPase domain, ankyrin repeat and PH domain 7
17311
0.19
chr1_247570539_247571127 0.36 NLRP3
NLR family, pyrin domain containing 3
8625
0.18
chr1_169670629_169671082 0.36 SELL
selectin L
9984
0.2
chr7_151125685_151126226 0.36 RP4-555L14.4

1186
0.33
chr19_4088417_4088592 0.36 MAP2K2
mitogen-activated protein kinase kinase 2
12541
0.11
chr20_31169576_31169970 0.36 RP11-410N8.1

8
0.97
chr4_2365742_2365893 0.36 ZFYVE28
zinc finger, FYVE domain containing 28
714
0.67
chr3_43386732_43386964 0.36 RP11-188P20.3

2287
0.28
chr1_1073051_1073561 0.36 C1orf159
chromosome 1 open reading frame 159
21565
0.08
chr3_128736783_128736934 0.36 EFCC1
EF-hand and coiled-coil domain containing 1
16386
0.13
chr15_81608011_81608276 0.36 STARD5
StAR-related lipid transfer (START) domain containing 5
8323
0.18
chr14_23011658_23011809 0.35 TRAJ15
T cell receptor alpha joining 15
13153
0.1
chr14_61903705_61903865 0.35 PRKCH
protein kinase C, eta
5491
0.27
chr19_8774866_8775027 0.35 ACTL9
actin-like 9
34226
0.15

Histogram of CRE-TSS distances for CREs targeted by :

Histogram of

Rank distribution of CRE target scores:

Histogram of target CRE score.

Distribution of target CREs across different genomic regions:

Weighted Piechart of Weighted Piechart of Weighted Piechart of

Network of associatons between targets according to the STRING database.

StringDB image

First level regulatory network of PPARG

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.6 GO:0035405 histone-threonine phosphorylation(GO:0035405)
0.2 1.2 GO:0070670 response to interleukin-4(GO:0070670)
0.2 0.6 GO:0045343 MHC class I biosynthetic process(GO:0045341) regulation of MHC class I biosynthetic process(GO:0045343)
0.2 0.6 GO:0031580 membrane raft polarization(GO:0001766) membrane raft distribution(GO:0031580)
0.2 0.2 GO:0034112 positive regulation of homotypic cell-cell adhesion(GO:0034112)
0.2 0.5 GO:0006154 adenosine catabolic process(GO:0006154)
0.2 0.5 GO:0030854 positive regulation of granulocyte differentiation(GO:0030854)
0.2 0.3 GO:0030223 neutrophil differentiation(GO:0030223)
0.2 0.6 GO:0001911 negative regulation of leukocyte mediated cytotoxicity(GO:0001911)
0.1 0.4 GO:0030186 melatonin metabolic process(GO:0030186) melatonin biosynthetic process(GO:0030187)
0.1 0.1 GO:0048537 mucosal-associated lymphoid tissue development(GO:0048537)
0.1 0.4 GO:0061526 acetylcholine secretion, neurotransmission(GO:0014055) regulation of acetylcholine secretion, neurotransmission(GO:0014056) acetylcholine secretion(GO:0061526)
0.1 0.4 GO:0042091 interleukin-10 biosynthetic process(GO:0042091) regulation of interleukin-10 biosynthetic process(GO:0045074)
0.1 0.2 GO:0002890 negative regulation of B cell mediated immunity(GO:0002713) negative regulation of immunoglobulin mediated immune response(GO:0002890)
0.1 0.5 GO:0033152 immunoglobulin V(D)J recombination(GO:0033152)
0.1 0.4 GO:0001574 ganglioside biosynthetic process(GO:0001574)
0.1 0.5 GO:0015014 heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.1 0.5 GO:1901339 activation of store-operated calcium channel activity(GO:0032237) regulation of store-operated calcium channel activity(GO:1901339) positive regulation of store-operated calcium channel activity(GO:1901341)
0.1 0.7 GO:0006538 glutamate catabolic process(GO:0006538)
0.1 0.1 GO:0035066 positive regulation of histone acetylation(GO:0035066) positive regulation of protein acetylation(GO:1901985) positive regulation of peptidyl-lysine acetylation(GO:2000758)
0.1 0.6 GO:0007195 adenylate cyclase-inhibiting dopamine receptor signaling pathway(GO:0007195)
0.1 0.3 GO:0045591 positive regulation of regulatory T cell differentiation(GO:0045591)
0.1 0.4 GO:0019987 obsolete negative regulation of anti-apoptosis(GO:0019987)
0.1 0.1 GO:0002326 B cell lineage commitment(GO:0002326)
0.1 0.3 GO:0043301 negative regulation of myeloid leukocyte mediated immunity(GO:0002887) negative regulation of leukocyte degranulation(GO:0043301)
0.1 0.5 GO:0006924 activation-induced cell death of T cells(GO:0006924)
0.1 0.5 GO:0002726 positive regulation of T cell cytokine production(GO:0002726)
0.1 0.3 GO:0002667 lymphocyte anergy(GO:0002249) regulation of T cell anergy(GO:0002667) positive regulation of T cell anergy(GO:0002669) T cell anergy(GO:0002870) regulation of lymphocyte anergy(GO:0002911) positive regulation of lymphocyte anergy(GO:0002913)
0.1 0.3 GO:0046813 receptor-mediated virion attachment to host cell(GO:0046813)
0.1 0.3 GO:0006772 thiamine metabolic process(GO:0006772)
0.1 0.3 GO:0010867 positive regulation of triglyceride biosynthetic process(GO:0010867)
0.1 0.3 GO:0018076 N-terminal peptidyl-lysine acetylation(GO:0018076)
0.1 0.3 GO:0018094 protein polyglycylation(GO:0018094)
0.1 0.3 GO:0010040 response to iron(II) ion(GO:0010040)
0.1 0.4 GO:0043951 negative regulation of cAMP-mediated signaling(GO:0043951)
0.1 0.5 GO:0046827 positive regulation of protein export from nucleus(GO:0046827)
0.1 0.1 GO:0050862 positive regulation of T cell receptor signaling pathway(GO:0050862)
0.1 0.3 GO:0007500 mesodermal cell fate determination(GO:0007500)
0.1 0.9 GO:0045086 positive regulation of interleukin-2 biosynthetic process(GO:0045086)
0.1 0.8 GO:0051828 entry into host cell(GO:0030260) entry into host(GO:0044409) entry into cell of other organism involved in symbiotic interaction(GO:0051806) entry into other organism involved in symbiotic interaction(GO:0051828)
0.1 0.2 GO:0014805 smooth muscle adaptation(GO:0014805)
0.1 0.1 GO:0002666 T cell tolerance induction(GO:0002517) regulation of T cell tolerance induction(GO:0002664) positive regulation of T cell tolerance induction(GO:0002666)
0.1 1.3 GO:0046834 lipid phosphorylation(GO:0046834)
0.1 0.2 GO:0002335 mature B cell differentiation involved in immune response(GO:0002313) mature B cell differentiation(GO:0002335)
0.1 0.2 GO:0032661 interleukin-18 production(GO:0032621) regulation of interleukin-18 production(GO:0032661)
0.1 2.0 GO:0050690 regulation of defense response to virus by virus(GO:0050690)
0.1 0.1 GO:0021938 smoothened signaling pathway involved in regulation of cerebellar granule cell precursor cell proliferation(GO:0021938)
0.1 0.2 GO:0021913 regulation of transcription from RNA polymerase II promoter involved in ventral spinal cord interneuron specification(GO:0021913)
0.1 0.5 GO:0007172 signal complex assembly(GO:0007172)
0.1 0.2 GO:0045056 transcytosis(GO:0045056)
0.1 0.3 GO:0048643 positive regulation of skeletal muscle tissue development(GO:0048643)
0.1 0.1 GO:0002677 negative regulation of chronic inflammatory response(GO:0002677)
0.1 0.3 GO:0045059 positive thymic T cell selection(GO:0045059)
0.1 0.4 GO:0007023 post-chaperonin tubulin folding pathway(GO:0007023)
0.1 0.2 GO:0006089 lactate metabolic process(GO:0006089)
0.1 0.5 GO:0008653 lipopolysaccharide metabolic process(GO:0008653)
0.1 0.1 GO:0048304 positive regulation of isotype switching to IgG isotypes(GO:0048304)
0.1 0.2 GO:0032203 telomere formation via telomerase(GO:0032203)
0.1 1.0 GO:0032012 regulation of ARF protein signal transduction(GO:0032012)
0.1 0.3 GO:0000089 mitotic metaphase(GO:0000089)
0.1 0.1 GO:0015015 heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.1 0.2 GO:0060235 lens induction in camera-type eye(GO:0060235)
0.1 0.1 GO:0006883 cellular sodium ion homeostasis(GO:0006883)
0.1 0.1 GO:0014874 response to stimulus involved in regulation of muscle adaptation(GO:0014874)
0.1 0.1 GO:0061154 endothelial tube morphogenesis(GO:0061154)
0.1 0.3 GO:0010642 negative regulation of platelet-derived growth factor receptor signaling pathway(GO:0010642)
0.1 0.3 GO:0045091 regulation of single stranded viral RNA replication via double stranded DNA intermediate(GO:0045091)
0.1 0.2 GO:0042118 endothelial cell activation(GO:0042118)
0.1 0.3 GO:0008588 release of cytoplasmic sequestered NF-kappaB(GO:0008588)
0.1 0.3 GO:0007097 nuclear migration(GO:0007097)
0.1 0.3 GO:0006685 sphingomyelin catabolic process(GO:0006685)
0.1 0.2 GO:0021529 spinal cord oligodendrocyte cell differentiation(GO:0021529) spinal cord oligodendrocyte cell fate specification(GO:0021530) oligodendrocyte cell fate specification(GO:0021778) glial cell fate specification(GO:0021780)
0.1 0.2 GO:0045990 carbon catabolite regulation of transcription(GO:0045990) regulation of transcription by glucose(GO:0046015)
0.1 0.1 GO:0046085 adenosine metabolic process(GO:0046085)
0.1 0.2 GO:0035025 positive regulation of Rho protein signal transduction(GO:0035025)
0.1 0.3 GO:0042989 sequestering of actin monomers(GO:0042989)
0.1 0.1 GO:0002093 auditory receptor cell morphogenesis(GO:0002093) auditory receptor cell stereocilium organization(GO:0060088)
0.1 0.1 GO:0002251 organ or tissue specific immune response(GO:0002251)
0.1 0.1 GO:0021860 pyramidal neuron differentiation(GO:0021859) pyramidal neuron development(GO:0021860)
0.1 0.1 GO:0071503 response to heparin(GO:0071503)
0.1 0.6 GO:0043508 negative regulation of JUN kinase activity(GO:0043508)
0.1 0.3 GO:0006198 cAMP catabolic process(GO:0006198)
0.1 0.4 GO:0002063 chondrocyte development(GO:0002063)
0.1 0.2 GO:0003197 endocardial cushion development(GO:0003197)
0.1 0.1 GO:0006925 inflammatory cell apoptotic process(GO:0006925)
0.1 0.3 GO:0001573 ganglioside metabolic process(GO:0001573)
0.1 0.2 GO:0001845 phagolysosome assembly(GO:0001845) phagosome maturation(GO:0090382)
0.1 0.2 GO:0070777 D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
0.1 0.2 GO:0003077 obsolete negative regulation of diuresis(GO:0003077)
0.1 0.2 GO:0034085 establishment of sister chromatid cohesion(GO:0034085) cohesin loading(GO:0071921) regulation of cohesin loading(GO:0071922)
0.1 0.2 GO:0002430 complement receptor mediated signaling pathway(GO:0002430)
0.1 0.7 GO:0034199 activation of protein kinase A activity(GO:0034199)
0.1 0.1 GO:0071635 negative regulation of transforming growth factor beta production(GO:0071635)
0.1 0.2 GO:0010614 negative regulation of cardiac muscle hypertrophy(GO:0010614)
0.1 0.3 GO:0048096 chromatin-mediated maintenance of transcription(GO:0048096)
0.0 0.6 GO:0000303 response to superoxide(GO:0000303)
0.0 0.2 GO:0035751 lysosomal lumen acidification(GO:0007042) regulation of lysosomal lumen pH(GO:0035751)
0.0 0.1 GO:0001820 serotonin secretion(GO:0001820)
0.0 0.1 GO:0048563 post-embryonic organ morphogenesis(GO:0048563)
0.0 1.5 GO:0050772 positive regulation of axonogenesis(GO:0050772)
0.0 0.1 GO:0052251 induction by organism of defense response of other organism involved in symbiotic interaction(GO:0052251)
0.0 0.4 GO:0060039 pericardium development(GO:0060039)
0.0 0.0 GO:0034983 peptidyl-lysine deacetylation(GO:0034983)
0.0 0.6 GO:0002637 regulation of immunoglobulin production(GO:0002637)
0.0 0.0 GO:0045589 regulation of regulatory T cell differentiation(GO:0045589)
0.0 0.1 GO:0006922 obsolete cleavage of lamin involved in execution phase of apoptosis(GO:0006922)
0.0 0.0 GO:0072540 T-helper cell lineage commitment(GO:0002295) CD4-positive, alpha-beta T cell lineage commitment(GO:0043373) memory T cell differentiation(GO:0043379) regulation of memory T cell differentiation(GO:0043380) positive regulation of memory T cell differentiation(GO:0043382) T-helper 17 type immune response(GO:0072538) T-helper 17 cell differentiation(GO:0072539) T-helper 17 cell lineage commitment(GO:0072540) regulation of T-helper 17 type immune response(GO:2000316) positive regulation of T-helper 17 type immune response(GO:2000318) regulation of T-helper 17 cell differentiation(GO:2000319) positive regulation of T-helper 17 cell differentiation(GO:2000321) regulation of T-helper 17 cell lineage commitment(GO:2000328) positive regulation of T-helper 17 cell lineage commitment(GO:2000330)
0.0 0.1 GO:0009405 pathogenesis(GO:0009405)
0.0 0.2 GO:0072531 pyrimidine-containing compound transmembrane transport(GO:0072531)
0.0 0.1 GO:0007035 vacuolar acidification(GO:0007035)
0.0 0.2 GO:0031340 positive regulation of vesicle fusion(GO:0031340)
0.0 0.1 GO:1903306 negative regulation of regulated secretory pathway(GO:1903306)
0.0 0.1 GO:0032808 lacrimal gland development(GO:0032808)
0.0 0.1 GO:0045722 positive regulation of gluconeogenesis(GO:0045722)
0.0 0.1 GO:0008053 mitochondrial fusion(GO:0008053)
0.0 0.6 GO:0006044 N-acetylglucosamine metabolic process(GO:0006044)
0.0 0.2 GO:0032776 DNA methylation on cytosine(GO:0032776) C-5 methylation of cytosine(GO:0090116)
0.0 0.0 GO:0070933 histone H3 deacetylation(GO:0070932) histone H4 deacetylation(GO:0070933)
0.0 0.1 GO:0043457 regulation of cellular respiration(GO:0043457)
0.0 0.0 GO:0014002 astrocyte development(GO:0014002)
0.0 0.0 GO:0031936 negative regulation of chromatin silencing(GO:0031936)
0.0 0.2 GO:0002098 tRNA wobble base modification(GO:0002097) tRNA wobble uridine modification(GO:0002098) tRNA thio-modification(GO:0034227)
0.0 0.3 GO:0030889 negative regulation of B cell proliferation(GO:0030889)
0.0 0.1 GO:0033033 negative regulation of myeloid cell apoptotic process(GO:0033033)
0.0 0.1 GO:0006659 phosphatidylserine biosynthetic process(GO:0006659)
0.0 0.5 GO:0031648 protein destabilization(GO:0031648)
0.0 0.2 GO:0000154 rRNA modification(GO:0000154)
0.0 0.1 GO:0010572 positive regulation of platelet activation(GO:0010572)
0.0 0.1 GO:0009448 gamma-aminobutyric acid metabolic process(GO:0009448)
0.0 0.1 GO:0006435 threonyl-tRNA aminoacylation(GO:0006435)
0.0 0.5 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.0 0.1 GO:0072583 synaptic vesicle recycling(GO:0036465) synaptic vesicle endocytosis(GO:0048488) clathrin-mediated endocytosis(GO:0072583)
0.0 0.0 GO:0002019 regulation of renal output by angiotensin(GO:0002019)
0.0 0.1 GO:0035268 protein mannosylation(GO:0035268) protein O-linked mannosylation(GO:0035269) mannosylation(GO:0097502)
0.0 0.3 GO:0045745 positive regulation of G-protein coupled receptor protein signaling pathway(GO:0045745)
0.0 0.2 GO:0042518 negative regulation of tyrosine phosphorylation of Stat3 protein(GO:0042518)
0.0 0.0 GO:0071699 olfactory placode formation(GO:0030910) olfactory placode development(GO:0071698) olfactory placode morphogenesis(GO:0071699)
0.0 0.4 GO:0031146 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process(GO:0031146)
0.0 0.0 GO:0032966 negative regulation of collagen biosynthetic process(GO:0032966)
0.0 0.2 GO:0017182 peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183)
0.0 0.1 GO:0032790 ribosome disassembly(GO:0032790)
0.0 0.1 GO:0002823 negative regulation of adaptive immune response(GO:0002820) negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains(GO:0002823)
0.0 0.1 GO:0071277 cellular response to calcium ion(GO:0071277)
0.0 0.2 GO:0007175 negative regulation of epidermal growth factor-activated receptor activity(GO:0007175)
0.0 0.1 GO:0036037 CD8-positive, alpha-beta T cell activation(GO:0036037) CD8-positive, alpha-beta T cell differentiation(GO:0043374)
0.0 0.1 GO:0002323 natural killer cell activation involved in immune response(GO:0002323) natural killer cell degranulation(GO:0043320)
0.0 0.2 GO:0051001 negative regulation of nitric-oxide synthase activity(GO:0051001)
0.0 0.0 GO:0071830 chylomicron remnant clearance(GO:0034382) triglyceride-rich lipoprotein particle clearance(GO:0071830)
0.0 0.1 GO:0061099 negative regulation of protein tyrosine kinase activity(GO:0061099)
0.0 0.1 GO:0071542 dopaminergic neuron differentiation(GO:0071542)
0.0 0.1 GO:0015864 pyrimidine nucleoside transport(GO:0015864)
0.0 0.0 GO:0043096 purine ribonucleoside salvage(GO:0006166) adenine salvage(GO:0006168) purine nucleobase salvage(GO:0043096) adenine metabolic process(GO:0046083) adenine biosynthetic process(GO:0046084)
0.0 0.2 GO:0007256 activation of JNKK activity(GO:0007256)
0.0 0.0 GO:2001259 positive regulation of calcium ion transmembrane transporter activity(GO:1901021) positive regulation of cation channel activity(GO:2001259)
0.0 0.3 GO:0000090 mitotic anaphase(GO:0000090)
0.0 0.7 GO:0006611 protein export from nucleus(GO:0006611)
0.0 0.0 GO:0048670 regulation of collateral sprouting(GO:0048670)
0.0 0.1 GO:0032733 positive regulation of interleukin-10 production(GO:0032733)
0.0 0.1 GO:0036072 intramembranous ossification(GO:0001957) direct ossification(GO:0036072)
0.0 0.1 GO:0042346 positive regulation of NF-kappaB import into nucleus(GO:0042346)
0.0 0.1 GO:0072526 pyridine-containing compound catabolic process(GO:0072526)
0.0 0.2 GO:0019883 antigen processing and presentation of endogenous antigen(GO:0019883)
0.0 0.1 GO:0033088 negative regulation of immature T cell proliferation(GO:0033087) negative regulation of immature T cell proliferation in thymus(GO:0033088)
0.0 0.7 GO:0045576 mast cell activation(GO:0045576)
0.0 0.1 GO:0051026 chiasma assembly(GO:0051026)
0.0 0.1 GO:0010758 regulation of macrophage chemotaxis(GO:0010758)
0.0 0.0 GO:0070669 response to interleukin-2(GO:0070669)
0.0 0.1 GO:0021681 cerebellar granular layer development(GO:0021681) cerebellar granular layer morphogenesis(GO:0021683) cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707)
0.0 0.1 GO:0033629 negative regulation of cell adhesion mediated by integrin(GO:0033629)
0.0 0.0 GO:0003211 cardiac chamber formation(GO:0003207) cardiac ventricle formation(GO:0003211)
0.0 0.1 GO:0010508 positive regulation of autophagy(GO:0010508)
0.0 1.4 GO:0031294 lymphocyte costimulation(GO:0031294) T cell costimulation(GO:0031295)
0.0 0.3 GO:0048741 skeletal muscle fiber development(GO:0048741)
0.0 0.1 GO:0009143 nucleoside triphosphate catabolic process(GO:0009143)
0.0 0.1 GO:0002689 negative regulation of leukocyte chemotaxis(GO:0002689)
0.0 0.1 GO:0070682 proteasome regulatory particle assembly(GO:0070682)
0.0 0.0 GO:0042596 fear response(GO:0042596)
0.0 0.1 GO:0006384 transcription initiation from RNA polymerase III promoter(GO:0006384)
0.0 0.1 GO:0021869 forebrain ventricular zone progenitor cell division(GO:0021869)
0.0 0.0 GO:0072216 positive regulation of metanephros development(GO:0072216)
0.0 0.1 GO:0031665 negative regulation of lipopolysaccharide-mediated signaling pathway(GO:0031665)
0.0 0.1 GO:0070857 regulation of bile acid biosynthetic process(GO:0070857) regulation of bile acid metabolic process(GO:1904251)
0.0 0.3 GO:0000085 mitotic G2 phase(GO:0000085) G2 phase(GO:0051319)
0.0 0.0 GO:0003148 outflow tract septum morphogenesis(GO:0003148)
0.0 0.1 GO:0042094 interleukin-2 biosynthetic process(GO:0042094)
0.0 0.1 GO:0006474 N-terminal protein amino acid acetylation(GO:0006474)
0.0 0.1 GO:0048711 positive regulation of astrocyte differentiation(GO:0048711)
0.0 0.3 GO:0032456 endocytic recycling(GO:0032456)
0.0 0.1 GO:0051322 anaphase(GO:0051322)
0.0 0.1 GO:0001955 blood vessel maturation(GO:0001955)
0.0 0.1 GO:0002418 immune response to tumor cell(GO:0002418)
0.0 0.1 GO:0050651 dermatan sulfate proteoglycan biosynthetic process(GO:0050651)
0.0 0.1 GO:0010737 protein kinase A signaling(GO:0010737)
0.0 0.0 GO:0031664 regulation of lipopolysaccharide-mediated signaling pathway(GO:0031664)
0.0 0.2 GO:0060040 retinal bipolar neuron differentiation(GO:0060040)
0.0 0.1 GO:0016199 axon midline choice point recognition(GO:0016199)
0.0 0.2 GO:1904376 negative regulation of establishment of protein localization to plasma membrane(GO:0090005) negative regulation of protein localization to plasma membrane(GO:1903077) negative regulation of protein localization to cell periphery(GO:1904376)
0.0 0.1 GO:0060437 lung growth(GO:0060437)
0.0 0.3 GO:0007217 tachykinin receptor signaling pathway(GO:0007217)
0.0 0.1 GO:0007130 synaptonemal complex assembly(GO:0007130)
0.0 0.2 GO:0000183 chromatin silencing at rDNA(GO:0000183)
0.0 0.2 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.0 0.2 GO:0009298 GDP-mannose biosynthetic process(GO:0009298)
0.0 0.1 GO:0071392 cellular response to estradiol stimulus(GO:0071392)
0.0 0.0 GO:0034122 negative regulation of toll-like receptor signaling pathway(GO:0034122)
0.0 0.2 GO:0097094 cranial suture morphogenesis(GO:0060363) craniofacial suture morphogenesis(GO:0097094)
0.0 0.2 GO:0042832 response to protozoan(GO:0001562) defense response to protozoan(GO:0042832)
0.0 0.1 GO:0048087 positive regulation of developmental pigmentation(GO:0048087)
0.0 0.1 GO:0030174 regulation of DNA-dependent DNA replication initiation(GO:0030174)
0.0 0.1 GO:0006610 ribosomal protein import into nucleus(GO:0006610)
0.0 0.1 GO:0070340 detection of bacterial lipoprotein(GO:0042494) detection of bacterial lipopeptide(GO:0070340)
0.0 0.1 GO:0045136 development of secondary sexual characteristics(GO:0045136)
0.0 0.1 GO:2001012 mesenchymal cell differentiation involved in kidney development(GO:0072161) metanephric mesenchymal cell differentiation(GO:0072162) mesenchymal cell differentiation involved in renal system development(GO:2001012)
0.0 0.0 GO:0048617 embryonic foregut morphogenesis(GO:0048617)
0.0 0.1 GO:0010452 histone H3-K36 methylation(GO:0010452)
0.0 0.1 GO:0060214 endocardium formation(GO:0060214)
0.0 0.1 GO:0045117 azole transport(GO:0045117)
0.0 0.1 GO:0045354 interferon-alpha biosynthetic process(GO:0045349) regulation of interferon-alpha biosynthetic process(GO:0045354) positive regulation of interferon-alpha biosynthetic process(GO:0045356)
0.0 0.4 GO:0042517 positive regulation of tyrosine phosphorylation of Stat3 protein(GO:0042517)
0.0 0.1 GO:2000344 positive regulation of acrosome reaction(GO:2000344)
0.0 0.2 GO:0060770 negative regulation of epithelial cell proliferation involved in prostate gland development(GO:0060770)
0.0 0.1 GO:0007191 adenylate cyclase-activating dopamine receptor signaling pathway(GO:0007191)
0.0 0.1 GO:1902808 traversing start control point of mitotic cell cycle(GO:0007089) positive regulation of G1/S transition of mitotic cell cycle(GO:1900087) positive regulation of cell cycle G1/S phase transition(GO:1902808)
0.0 0.1 GO:1901978 positive regulation of spindle checkpoint(GO:0090232) regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090266) positive regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090267) positive regulation of cell cycle checkpoint(GO:1901978) regulation of mitotic spindle checkpoint(GO:1903504)
0.0 0.2 GO:0060765 regulation of androgen receptor signaling pathway(GO:0060765)
0.0 0.0 GO:0071421 manganese ion transmembrane transport(GO:0071421)
0.0 0.2 GO:0045948 positive regulation of translational initiation(GO:0045948)
0.0 0.1 GO:0007341 penetration of zona pellucida(GO:0007341)
0.0 0.1 GO:0050798 activated T cell proliferation(GO:0050798)
0.0 0.2 GO:0035235 ionotropic glutamate receptor signaling pathway(GO:0035235)
0.0 0.1 GO:0034723 DNA replication-dependent nucleosome organization(GO:0034723)
0.0 0.1 GO:0060218 hematopoietic stem cell differentiation(GO:0060218)
0.0 0.1 GO:1901797 negative regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043518) negative regulation of signal transduction by p53 class mediator(GO:1901797)
0.0 0.2 GO:0050860 regulation of T cell receptor signaling pathway(GO:0050856) negative regulation of antigen receptor-mediated signaling pathway(GO:0050858) negative regulation of T cell receptor signaling pathway(GO:0050860)
0.0 0.1 GO:0046426 negative regulation of JAK-STAT cascade(GO:0046426) negative regulation of STAT cascade(GO:1904893)
0.0 0.1 GO:0008291 acetylcholine metabolic process(GO:0008291) acetate ester metabolic process(GO:1900619)
0.0 0.1 GO:0048535 lymph node development(GO:0048535)
0.0 0.2 GO:0001662 behavioral fear response(GO:0001662)
0.0 0.2 GO:0008625 extrinsic apoptotic signaling pathway via death domain receptors(GO:0008625) extrinsic apoptotic signaling pathway(GO:0097191)
0.0 0.5 GO:0007190 activation of adenylate cyclase activity(GO:0007190)
0.0 0.1 GO:0071816 protein insertion into ER membrane(GO:0045048) tail-anchored membrane protein insertion into ER membrane(GO:0071816)
0.0 0.1 GO:0034625 fatty acid elongation, monounsaturated fatty acid(GO:0034625)
0.0 0.1 GO:0007343 egg activation(GO:0007343)
0.0 0.3 GO:1903038 negative regulation of T cell activation(GO:0050868) negative regulation of leukocyte cell-cell adhesion(GO:1903038)
0.0 0.0 GO:0030241 skeletal muscle myosin thick filament assembly(GO:0030241) myosin filament assembly(GO:0031034) striated muscle myosin thick filament assembly(GO:0071688)
0.0 0.2 GO:0006546 glycine catabolic process(GO:0006546)
0.0 0.1 GO:0000729 DNA double-strand break processing(GO:0000729)
0.0 0.1 GO:0015705 iodide transport(GO:0015705)
0.0 0.1 GO:0051382 kinetochore assembly(GO:0051382)
0.0 0.2 GO:0007158 neuron cell-cell adhesion(GO:0007158)
0.0 0.1 GO:0006477 protein sulfation(GO:0006477)
0.0 0.1 GO:0030505 inorganic diphosphate transport(GO:0030505)
0.0 0.1 GO:0033261 obsolete regulation of S phase(GO:0033261)
0.0 0.2 GO:0050910 detection of mechanical stimulus involved in sensory perception of sound(GO:0050910)
0.0 0.3 GO:0030252 growth hormone secretion(GO:0030252)
0.0 0.0 GO:0003402 planar cell polarity pathway involved in axis elongation(GO:0003402)
0.0 0.0 GO:0051665 membrane raft localization(GO:0051665)
0.0 0.1 GO:0021853 interneuron migration from the subpallium to the cortex(GO:0021830) cerebral cortex GABAergic interneuron migration(GO:0021853) cerebral cortex GABAergic interneuron development(GO:0021894) interneuron migration(GO:1904936)
0.0 0.1 GO:0048263 determination of dorsal/ventral asymmetry(GO:0048262) determination of dorsal identity(GO:0048263)
0.0 0.1 GO:0022614 membrane to membrane docking(GO:0022614)
0.0 0.1 GO:0009301 snRNA transcription(GO:0009301)
0.0 0.1 GO:0021571 rhombomere 5 development(GO:0021571)
0.0 0.1 GO:0006498 N-terminal protein lipidation(GO:0006498)
0.0 0.1 GO:0071428 rRNA-containing ribonucleoprotein complex export from nucleus(GO:0071428)
0.0 0.3 GO:0070536 protein K63-linked deubiquitination(GO:0070536)
0.0 0.1 GO:0032486 Rap protein signal transduction(GO:0032486)
0.0 0.1 GO:0046831 regulation of RNA export from nucleus(GO:0046831)
0.0 0.0 GO:0018119 protein nitrosylation(GO:0017014) peptidyl-cysteine S-nitrosylation(GO:0018119)
0.0 0.0 GO:0051970 negative regulation of transmission of nerve impulse(GO:0051970)
0.0 0.1 GO:0050710 negative regulation of cytokine secretion(GO:0050710)
0.0 0.0 GO:0097576 vacuole fusion(GO:0097576)
0.0 0.1 GO:0048251 elastic fiber assembly(GO:0048251)
0.0 0.5 GO:0006084 acetyl-CoA metabolic process(GO:0006084)
0.0 0.0 GO:0019673 GDP-mannose metabolic process(GO:0019673)
0.0 0.4 GO:0033209 tumor necrosis factor-mediated signaling pathway(GO:0033209)
0.0 0.0 GO:0070233 negative regulation of T cell apoptotic process(GO:0070233)
0.0 0.2 GO:0098927 early endosome to late endosome transport(GO:0045022) vesicle-mediated transport between endosomal compartments(GO:0098927)
0.0 0.1 GO:0048557 embryonic digestive tract morphogenesis(GO:0048557)
0.0 0.1 GO:0071168 protein localization to chromatin(GO:0071168)
0.0 0.1 GO:0043171 peptide catabolic process(GO:0043171)
0.0 0.1 GO:0009125 nucleoside monophosphate catabolic process(GO:0009125)
0.0 0.1 GO:0050957 equilibrioception(GO:0050957)
0.0 0.0 GO:0017085 response to insecticide(GO:0017085)
0.0 0.2 GO:0045737 positive regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045737) positive regulation of cyclin-dependent protein kinase activity(GO:1904031)
0.0 0.1 GO:0007000 nucleolus organization(GO:0007000)
0.0 0.1 GO:0021696 cerebellar cortex morphogenesis(GO:0021696)
0.0 0.1 GO:1903393 positive regulation of focal adhesion assembly(GO:0051894) positive regulation of cell junction assembly(GO:1901890) positive regulation of adherens junction organization(GO:1903393)
0.0 0.3 GO:0048536 spleen development(GO:0048536)
0.0 0.1 GO:0051657 maintenance of organelle location(GO:0051657)
0.0 1.6 GO:0007159 leukocyte cell-cell adhesion(GO:0007159)
0.0 0.0 GO:0002282 microglial cell activation involved in immune response(GO:0002282)
0.0 0.5 GO:0006997 nucleus organization(GO:0006997)
0.0 0.0 GO:0050849 negative regulation of calcium-mediated signaling(GO:0050849)
0.0 0.0 GO:0042996 regulation of Golgi to plasma membrane protein transport(GO:0042996)
0.0 0.1 GO:0016556 mRNA modification(GO:0016556)
0.0 0.1 GO:0008354 germ cell migration(GO:0008354)
0.0 0.1 GO:0048070 regulation of developmental pigmentation(GO:0048070)
0.0 0.1 GO:0051597 response to methylmercury(GO:0051597)
0.0 0.1 GO:0000266 mitochondrial fission(GO:0000266)
0.0 0.2 GO:0090114 vesicle targeting, rough ER to cis-Golgi(GO:0048207) COPII vesicle coating(GO:0048208) COPII-coated vesicle budding(GO:0090114)
0.0 0.0 GO:0032366 intracellular sterol transport(GO:0032366) intracellular cholesterol transport(GO:0032367)
0.0 0.0 GO:0072111 cell proliferation involved in kidney development(GO:0072111)
0.0 0.3 GO:0006004 fucose metabolic process(GO:0006004)
0.0 0.0 GO:0034088 maintenance of sister chromatid cohesion(GO:0034086) maintenance of mitotic sister chromatid cohesion(GO:0034088)
0.0 0.2 GO:0046688 response to copper ion(GO:0046688)
0.0 0.1 GO:0010591 regulation of lamellipodium assembly(GO:0010591)
0.0 0.0 GO:0046599 regulation of centriole replication(GO:0046599)
0.0 0.0 GO:0002475 antigen processing and presentation via MHC class Ib(GO:0002475)
0.0 0.0 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
0.0 0.1 GO:0034314 Arp2/3 complex-mediated actin nucleation(GO:0034314)
0.0 0.1 GO:0070301 cellular response to hydrogen peroxide(GO:0070301)
0.0 0.1 GO:0034755 iron ion transmembrane transport(GO:0034755)
0.0 0.0 GO:0050765 negative regulation of phagocytosis(GO:0050765)
0.0 0.1 GO:0019509 L-methionine biosynthetic process from methylthioadenosine(GO:0019509)
0.0 0.1 GO:0032878 regulation of establishment or maintenance of cell polarity(GO:0032878)
0.0 0.0 GO:2001021 negative regulation of response to DNA damage stimulus(GO:2001021)
0.0 0.0 GO:0034421 post-translational protein acetylation(GO:0034421)
0.0 0.1 GO:0021520 spinal cord motor neuron cell fate specification(GO:0021520)
0.0 0.0 GO:0071267 amino acid salvage(GO:0043102) L-methionine biosynthetic process(GO:0071265) L-methionine salvage(GO:0071267)
0.0 0.2 GO:0042982 amyloid precursor protein metabolic process(GO:0042982)
0.0 0.1 GO:0051547 regulation of keratinocyte migration(GO:0051547) positive regulation of keratinocyte migration(GO:0051549)
0.0 0.2 GO:0030101 natural killer cell activation(GO:0030101)
0.0 0.2 GO:0007339 binding of sperm to zona pellucida(GO:0007339)
0.0 0.1 GO:0046325 negative regulation of glucose import(GO:0046325)
0.0 0.1 GO:0045116 protein neddylation(GO:0045116)
0.0 0.0 GO:0051088 PMA-inducible membrane protein ectodomain proteolysis(GO:0051088)
0.0 0.1 GO:0045906 negative regulation of vasoconstriction(GO:0045906)
0.0 0.2 GO:0000076 DNA replication checkpoint(GO:0000076)
0.0 0.1 GO:0060023 soft palate development(GO:0060023)
0.0 0.0 GO:0019367 fatty acid elongation, saturated fatty acid(GO:0019367)
0.0 0.1 GO:0046329 negative regulation of JNK cascade(GO:0046329)
0.0 0.0 GO:0021799 cerebral cortex radially oriented cell migration(GO:0021799)
0.0 0.3 GO:0042776 mitochondrial ATP synthesis coupled proton transport(GO:0042776)
0.0 0.2 GO:0007076 mitotic chromosome condensation(GO:0007076)
0.0 0.1 GO:0046689 response to mercury ion(GO:0046689)
0.0 0.1 GO:0009048 dosage compensation by inactivation of X chromosome(GO:0009048)
0.0 0.1 GO:2001257 regulation of calcium ion transmembrane transporter activity(GO:1901019) regulation of cation channel activity(GO:2001257)
0.0 0.1 GO:0000733 DNA strand renaturation(GO:0000733)
0.0 0.0 GO:0032543 mitochondrial translation(GO:0032543)
0.0 0.1 GO:0010972 negative regulation of G2/M transition of mitotic cell cycle(GO:0010972) negative regulation of cell cycle G2/M phase transition(GO:1902750)
0.0 0.1 GO:0070837 dehydroascorbic acid transport(GO:0070837)
0.0 0.0 GO:0055078 sodium ion homeostasis(GO:0055078)
0.0 0.1 GO:0008608 attachment of spindle microtubules to kinetochore(GO:0008608)
0.0 0.1 GO:0098543 detection of other organism(GO:0098543)
0.0 0.0 GO:0010957 negative regulation of calcidiol 1-monooxygenase activity(GO:0010956) negative regulation of vitamin D biosynthetic process(GO:0010957) negative regulation of vitamin metabolic process(GO:0046137)
0.0 0.1 GO:0007141 male meiosis I(GO:0007141)
0.0 0.1 GO:0006545 glycine biosynthetic process(GO:0006545)
0.0 0.1 GO:0090400 stress-induced premature senescence(GO:0090400)
0.0 0.1 GO:0022027 interkinetic nuclear migration(GO:0022027)
0.0 0.2 GO:0016578 histone deubiquitination(GO:0016578)
0.0 0.0 GO:0045875 negative regulation of sister chromatid cohesion(GO:0045875)
0.0 0.1 GO:0019852 L-ascorbic acid metabolic process(GO:0019852)
0.0 0.0 GO:0010640 regulation of platelet-derived growth factor receptor signaling pathway(GO:0010640)
0.0 0.0 GO:0021561 facial nerve development(GO:0021561)
0.0 0.0 GO:0032100 positive regulation of response to food(GO:0032097) positive regulation of appetite(GO:0032100)
0.0 0.0 GO:0002862 negative regulation of inflammatory response to antigenic stimulus(GO:0002862)
0.0 0.1 GO:0006983 ER overload response(GO:0006983)
0.0 0.1 GO:0050718 positive regulation of interleukin-1 beta secretion(GO:0050718)
0.0 0.0 GO:0001992 regulation of systemic arterial blood pressure by vasopressin(GO:0001992)
0.0 0.1 GO:0002507 tolerance induction(GO:0002507)
0.0 0.0 GO:0070254 mucus secretion(GO:0070254)
0.0 0.2 GO:0010390 histone monoubiquitination(GO:0010390)
0.0 0.3 GO:0071377 cellular response to glucagon stimulus(GO:0071377)
0.0 0.0 GO:0032375 negative regulation of sterol transport(GO:0032372) negative regulation of cholesterol transport(GO:0032375)
0.0 0.1 GO:0045292 mRNA cis splicing, via spliceosome(GO:0045292)
0.0 0.0 GO:0043615 astrocyte cell migration(GO:0043615)
0.0 0.1 GO:0000012 single strand break repair(GO:0000012)
0.0 0.3 GO:0043967 histone H4 acetylation(GO:0043967)
0.0 0.0 GO:0032048 phosphatidylglycerol biosynthetic process(GO:0006655) cardiolipin metabolic process(GO:0032048) cardiolipin biosynthetic process(GO:0032049) phosphatidylglycerol metabolic process(GO:0046471)
0.0 0.0 GO:0006642 triglyceride mobilization(GO:0006642)
0.0 0.0 GO:0002407 dendritic cell chemotaxis(GO:0002407) dendritic cell migration(GO:0036336)
0.0 0.0 GO:0010919 regulation of inositol phosphate biosynthetic process(GO:0010919)
0.0 0.0 GO:0034110 regulation of homotypic cell-cell adhesion(GO:0034110)
0.0 0.1 GO:0045767 obsolete regulation of anti-apoptosis(GO:0045767)
0.0 0.1 GO:0006552 leucine catabolic process(GO:0006552)
0.0 0.0 GO:0060080 inhibitory postsynaptic potential(GO:0060080)
0.0 1.1 GO:0006959 humoral immune response(GO:0006959)
0.0 0.1 GO:0048710 regulation of astrocyte differentiation(GO:0048710)
0.0 0.1 GO:0035162 embryonic hemopoiesis(GO:0035162)
0.0 0.0 GO:0051446 positive regulation of meiotic nuclear division(GO:0045836) positive regulation of meiotic cell cycle(GO:0051446)
0.0 0.0 GO:0006111 regulation of gluconeogenesis(GO:0006111)
0.0 0.0 GO:0040016 embryonic cleavage(GO:0040016)
0.0 0.1 GO:0015801 aromatic amino acid transport(GO:0015801)
0.0 0.1 GO:0044321 cellular response to leptin stimulus(GO:0044320) response to leptin(GO:0044321)
0.0 0.0 GO:0039703 single stranded viral RNA replication via double stranded DNA intermediate(GO:0039692) viral RNA genome replication(GO:0039694) RNA replication(GO:0039703)
0.0 0.1 GO:0032986 nucleosome disassembly(GO:0006337) chromatin disassembly(GO:0031498) protein-DNA complex disassembly(GO:0032986)
0.0 0.3 GO:0006308 DNA catabolic process(GO:0006308)
0.0 0.0 GO:0010042 response to manganese ion(GO:0010042)
0.0 0.1 GO:0000389 mRNA 3'-splice site recognition(GO:0000389)
0.0 0.2 GO:0000045 autophagosome assembly(GO:0000045) autophagosome organization(GO:1905037)
0.0 0.2 GO:0006700 C21-steroid hormone biosynthetic process(GO:0006700)
0.0 0.0 GO:0033160 positive regulation of protein import into nucleus, translocation(GO:0033160)
0.0 0.1 GO:0071636 positive regulation of transforming growth factor beta production(GO:0071636)
0.0 0.1 GO:0042745 circadian sleep/wake cycle(GO:0042745)
0.0 0.2 GO:0006349 regulation of gene expression by genetic imprinting(GO:0006349)
0.0 0.0 GO:0060586 multicellular organismal iron ion homeostasis(GO:0060586)
0.0 0.0 GO:0010761 fibroblast migration(GO:0010761)
0.0 0.0 GO:0051451 myoblast migration(GO:0051451)
0.0 0.0 GO:0019441 tryptophan catabolic process to kynurenine(GO:0019441)
0.0 0.2 GO:0051282 release of sequestered calcium ion into cytosol(GO:0051209) regulation of sequestering of calcium ion(GO:0051282) negative regulation of sequestering of calcium ion(GO:0051283) calcium ion transmembrane import into cytosol(GO:0097553) calcium ion import into cytosol(GO:1902656)
0.0 0.0 GO:0006420 arginyl-tRNA aminoacylation(GO:0006420)
0.0 0.6 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.0 0.0 GO:0060272 embryonic skeletal joint morphogenesis(GO:0060272) embryonic skeletal joint development(GO:0072498)
0.0 0.1 GO:1903078 positive regulation of establishment of protein localization to plasma membrane(GO:0090004) positive regulation of protein localization to plasma membrane(GO:1903078) positive regulation of protein localization to cell periphery(GO:1904377)
0.0 0.0 GO:0045359 interferon-beta biosynthetic process(GO:0045350) regulation of interferon-beta biosynthetic process(GO:0045357) positive regulation of interferon-beta biosynthetic process(GO:0045359)
0.0 0.1 GO:0006657 CDP-choline pathway(GO:0006657)
0.0 0.1 GO:0006906 vesicle fusion(GO:0006906)
0.0 0.1 GO:0009804 phenylpropanoid metabolic process(GO:0009698) coumarin metabolic process(GO:0009804)
0.0 0.0 GO:0009221 pyrimidine deoxyribonucleotide biosynthetic process(GO:0009221)
0.0 0.0 GO:0032607 interferon-alpha production(GO:0032607) regulation of interferon-alpha production(GO:0032647)
0.0 0.0 GO:0000305 response to oxygen radical(GO:0000305)
0.0 0.0 GO:0006296 nucleotide-excision repair, DNA incision, 5'-to lesion(GO:0006296)
0.0 0.0 GO:0050435 beta-amyloid metabolic process(GO:0050435)
0.0 0.0 GO:0048934 peripheral nervous system neuron differentiation(GO:0048934)
0.0 0.0 GO:0009313 oligosaccharide catabolic process(GO:0009313)
0.0 0.1 GO:0046149 porphyrin-containing compound catabolic process(GO:0006787) tetrapyrrole catabolic process(GO:0033015) heme catabolic process(GO:0042167) pigment catabolic process(GO:0046149)
0.0 0.0 GO:2000008 regulation of protein localization to cell surface(GO:2000008)
0.0 0.1 GO:0006482 protein demethylation(GO:0006482) protein dealkylation(GO:0008214)
0.0 0.0 GO:0060839 endothelial cell fate commitment(GO:0060839)
0.0 0.0 GO:0040009 regulation of growth rate(GO:0040009)
0.0 0.1 GO:0051290 protein heterotetramerization(GO:0051290)
0.0 0.1 GO:0046784 viral mRNA export from host cell nucleus(GO:0046784)
0.0 0.1 GO:0030501 positive regulation of bone mineralization(GO:0030501)
0.0 0.1 GO:0010310 regulation of hydrogen peroxide metabolic process(GO:0010310)
0.0 0.1 GO:0045109 intermediate filament organization(GO:0045109)
0.0 0.1 GO:0009812 flavonoid metabolic process(GO:0009812)
0.0 0.0 GO:0046479 glycosylceramide catabolic process(GO:0046477) glycosphingolipid catabolic process(GO:0046479)
0.0 0.1 GO:0051457 maintenance of protein location in nucleus(GO:0051457)
0.0 0.0 GO:0031645 negative regulation of neurological system process(GO:0031645)
0.0 0.0 GO:0070265 necrotic cell death(GO:0070265)
0.0 0.0 GO:1901419 regulation of response to alcohol(GO:1901419)
0.0 0.0 GO:0071318 cellular response to ATP(GO:0071318)
0.0 0.0 GO:0021978 telencephalon regionalization(GO:0021978)
0.0 0.1 GO:0030903 notochord development(GO:0030903)
0.0 0.0 GO:0034379 very-low-density lipoprotein particle assembly(GO:0034379)
0.0 0.1 GO:0019042 viral latency(GO:0019042)
0.0 0.1 GO:0050847 progesterone receptor signaling pathway(GO:0050847)
0.0 0.2 GO:0009303 rRNA transcription(GO:0009303)
0.0 0.1 GO:0006554 lysine metabolic process(GO:0006553) lysine catabolic process(GO:0006554)
0.0 0.3 GO:0001709 cell fate determination(GO:0001709)
0.0 0.0 GO:0090279 regulation of calcium ion import(GO:0090279)
0.0 0.0 GO:0019886 antigen processing and presentation of exogenous peptide antigen via MHC class II(GO:0019886)
0.0 0.1 GO:0048268 clathrin coat assembly(GO:0048268)
0.0 0.2 GO:0045646 regulation of erythrocyte differentiation(GO:0045646)
0.0 0.1 GO:0010039 response to iron ion(GO:0010039)
0.0 0.0 GO:0007129 synapsis(GO:0007129) chromosome organization involved in meiotic cell cycle(GO:0070192)
0.0 0.1 GO:0021854 hypothalamus development(GO:0021854)
0.0 0.1 GO:0051205 protein insertion into membrane(GO:0051205)
0.0 0.3 GO:0015914 phospholipid transport(GO:0015914)
0.0 0.0 GO:0060122 inner ear receptor stereocilium organization(GO:0060122)
0.0 0.7 GO:0007605 sensory perception of sound(GO:0007605)
0.0 0.0 GO:0072047 proximal/distal pattern formation involved in nephron development(GO:0072047) specification of nephron tubule identity(GO:0072081)
0.0 0.1 GO:0006528 asparagine metabolic process(GO:0006528)
0.0 0.0 GO:0060456 positive regulation of digestive system process(GO:0060456)
0.0 0.0 GO:0001961 positive regulation of cytokine-mediated signaling pathway(GO:0001961)
0.0 0.0 GO:0060831 smoothened signaling pathway involved in dorsal/ventral neural tube patterning(GO:0060831)
0.0 0.0 GO:0048679 regulation of axon regeneration(GO:0048679) regulation of neuron projection regeneration(GO:0070570)
0.0 0.0 GO:0042088 T-helper 1 type immune response(GO:0042088)
0.0 0.3 GO:0006370 7-methylguanosine mRNA capping(GO:0006370)
0.0 0.0 GO:0001921 positive regulation of receptor recycling(GO:0001921)
0.0 0.0 GO:0018027 peptidyl-lysine dimethylation(GO:0018027)
0.0 0.0 GO:0030488 tRNA methylation(GO:0030488)
0.0 0.0 GO:0043267 negative regulation of potassium ion transport(GO:0043267)
0.0 0.0 GO:0070296 sarcoplasmic reticulum calcium ion transport(GO:0070296)
0.0 0.0 GO:0031342 negative regulation of cell killing(GO:0031342)
0.0 0.0 GO:0010457 centriole-centriole cohesion(GO:0010457)
0.0 0.0 GO:0016093 polyprenol metabolic process(GO:0016093) dolichol metabolic process(GO:0019348)
0.0 0.1 GO:0008535 respiratory chain complex IV assembly(GO:0008535)
0.0 0.0 GO:0030828 positive regulation of cGMP biosynthetic process(GO:0030828)
0.0 0.0 GO:0071371 cellular response to gonadotropin stimulus(GO:0071371)
0.0 0.0 GO:0007210 serotonin receptor signaling pathway(GO:0007210)
0.0 0.1 GO:0050962 detection of light stimulus involved in visual perception(GO:0050908) detection of light stimulus involved in sensory perception(GO:0050962)
0.0 0.1 GO:0006400 tRNA modification(GO:0006400)
0.0 0.0 GO:0050955 thermoception(GO:0050955)
0.0 0.2 GO:0016254 preassembly of GPI anchor in ER membrane(GO:0016254)
0.0 0.4 GO:0022904 respiratory electron transport chain(GO:0022904)
0.0 0.0 GO:1904358 positive regulation of telomere maintenance via telomerase(GO:0032212) positive regulation of telomere maintenance via telomere lengthening(GO:1904358)
0.0 0.0 GO:0000281 mitotic cytokinesis(GO:0000281)
0.0 0.0 GO:0046940 nucleoside monophosphate phosphorylation(GO:0046940)
0.0 0.1 GO:0008089 anterograde axonal transport(GO:0008089)
0.0 0.0 GO:0051307 resolution of meiotic recombination intermediates(GO:0000712) meiotic chromosome separation(GO:0051307)
0.0 0.0 GO:0019377 glycolipid catabolic process(GO:0019377)
0.0 0.1 GO:0002021 response to dietary excess(GO:0002021)
0.0 0.2 GO:0070585 protein localization to mitochondrion(GO:0070585)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.6 GO:0005826 actomyosin contractile ring(GO:0005826)
0.1 0.5 GO:0000300 obsolete peripheral to membrane of membrane fraction(GO:0000300)
0.1 1.5 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.1 0.3 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.1 0.3 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)
0.1 0.3 GO:0070022 transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.1 0.3 GO:0030895 apolipoprotein B mRNA editing enzyme complex(GO:0030895)
0.1 0.8 GO:0061200 clathrin-sculpted gamma-aminobutyric acid transport vesicle(GO:0061200) clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane(GO:0061202)
0.1 0.4 GO:0000137 Golgi cis cisterna(GO:0000137)
0.1 0.8 GO:0042101 T cell receptor complex(GO:0042101)
0.1 0.1 GO:0060203 clathrin-sculpted glutamate transport vesicle(GO:0060199) clathrin-sculpted glutamate transport vesicle membrane(GO:0060203)
0.1 0.4 GO:0070688 MLL5-L complex(GO:0070688)
0.1 0.7 GO:0001772 immunological synapse(GO:0001772)
0.1 0.2 GO:0044462 external encapsulating structure part(GO:0044462)
0.1 0.3 GO:0014701 junctional sarcoplasmic reticulum membrane(GO:0014701)
0.1 0.4 GO:0030673 axolemma(GO:0030673)
0.1 0.2 GO:0032009 early phagosome(GO:0032009)
0.0 0.1 GO:0005896 interleukin-6 receptor complex(GO:0005896)
0.0 0.0 GO:0030312 external encapsulating structure(GO:0030312)
0.0 0.1 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.0 0.3 GO:0008290 F-actin capping protein complex(GO:0008290)
0.0 0.5 GO:0032156 septin complex(GO:0031105) septin cytoskeleton(GO:0032156)
0.0 0.2 GO:0044453 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229) nuclear membrane part(GO:0044453)
0.0 0.1 GO:0033270 paranode region of axon(GO:0033270)
0.0 0.1 GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.0 0.6 GO:0016514 SWI/SNF complex(GO:0016514)
0.0 0.2 GO:0044224 juxtaparanode region of axon(GO:0044224)
0.0 0.2 GO:0005883 neurofilament(GO:0005883)
0.0 0.3 GO:0031095 platelet dense tubular network membrane(GO:0031095)
0.0 0.1 GO:0048179 activin receptor complex(GO:0048179)
0.0 0.1 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.0 0.1 GO:0072487 MSL complex(GO:0072487)
0.0 0.0 GO:0001740 Barr body(GO:0001740)
0.0 0.1 GO:0070552 BRISC complex(GO:0070552)
0.0 0.2 GO:0000791 euchromatin(GO:0000791)
0.0 0.3 GO:0005697 telomerase holoenzyme complex(GO:0005697)
0.0 0.1 GO:0008540 proteasome regulatory particle, base subcomplex(GO:0008540)
0.0 0.1 GO:0032591 dendritic spine membrane(GO:0032591)
0.0 0.1 GO:0005827 polar microtubule(GO:0005827)
0.0 0.1 GO:0034992 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.0 0.1 GO:0033553 rDNA heterochromatin(GO:0033553)
0.0 0.9 GO:0005626 obsolete insoluble fraction(GO:0005626)
0.0 0.1 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.0 0.8 GO:0098636 integrin complex(GO:0008305) protein complex involved in cell adhesion(GO:0098636)
0.0 0.5 GO:0012507 ER to Golgi transport vesicle membrane(GO:0012507)
0.0 0.0 GO:0000138 Golgi trans cisterna(GO:0000138)
0.0 0.1 GO:0042788 polysomal ribosome(GO:0042788)
0.0 1.3 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.0 0.3 GO:0043209 myelin sheath(GO:0043209)
0.0 0.1 GO:0031254 uropod(GO:0001931) cell trailing edge(GO:0031254)
0.0 0.6 GO:0031594 neuromuscular junction(GO:0031594)
0.0 0.1 GO:0071818 BAT3 complex(GO:0071818) ER membrane insertion complex(GO:0072379)
0.0 0.3 GO:0030313 cell envelope(GO:0030313)
0.0 0.1 GO:0042598 obsolete vesicular fraction(GO:0042598)
0.0 0.6 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.0 0.4 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.0 0.4 GO:0005640 nuclear outer membrane(GO:0005640)
0.0 0.7 GO:0030175 filopodium(GO:0030175)
0.0 0.1 GO:0031904 endosome lumen(GO:0031904)
0.0 0.1 GO:0032590 dendrite membrane(GO:0032590)
0.0 0.3 GO:0031941 filamentous actin(GO:0031941)
0.0 0.1 GO:0016589 NURF complex(GO:0016589)
0.0 2.9 GO:0009897 external side of plasma membrane(GO:0009897)
0.0 0.1 GO:0034045 pre-autophagosomal structure membrane(GO:0034045)
0.0 0.1 GO:0001891 phagocytic cup(GO:0001891)
0.0 0.1 GO:0098984 asymmetric synapse(GO:0032279) neuron to neuron synapse(GO:0098984)
0.0 0.3 GO:0008278 cohesin complex(GO:0008278)
0.0 0.2 GO:0045261 proton-transporting ATP synthase complex, catalytic core F(1)(GO:0045261)
0.0 0.1 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 0.1 GO:0005682 U5 snRNP(GO:0005682)
0.0 0.1 GO:0030891 VCB complex(GO:0030891)
0.0 0.1 GO:0033011 perinuclear theca(GO:0033011)
0.0 0.3 GO:0005844 polysome(GO:0005844)
0.0 0.2 GO:0034362 low-density lipoprotein particle(GO:0034362)
0.0 0.2 GO:0000780 condensed nuclear chromosome, centromeric region(GO:0000780)
0.0 0.0 GO:0000125 PCAF complex(GO:0000125)
0.0 0.1 GO:0005797 Golgi medial cisterna(GO:0005797)
0.0 0.1 GO:0031465 Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
0.0 0.1 GO:0045179 apical cortex(GO:0045179)
0.0 0.4 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.0 0.1 GO:0090576 RNA polymerase III transcription factor complex(GO:0090576)
0.0 0.1 GO:0030121 AP-1 adaptor complex(GO:0030121)
0.0 0.2 GO:0034518 mRNA cap binding complex(GO:0005845) RNA cap binding complex(GO:0034518)
0.0 0.1 GO:0032133 chromosome passenger complex(GO:0032133)
0.0 0.1 GO:0072357 PTW/PP1 phosphatase complex(GO:0072357)
0.0 0.3 GO:0033276 transcription factor TFTC complex(GO:0033276)
0.0 0.2 GO:0005744 mitochondrial inner membrane presequence translocase complex(GO:0005744)
0.0 0.0 GO:0005677 chromatin silencing complex(GO:0005677)
0.0 0.4 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 0.2 GO:0005671 Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
0.0 0.2 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)
0.0 0.2 GO:0005775 vacuolar lumen(GO:0005775)
0.0 0.1 GO:0032444 activin responsive factor complex(GO:0032444)
0.0 0.1 GO:0030914 STAGA complex(GO:0030914)
0.0 0.1 GO:0031616 spindle pole centrosome(GO:0031616)
0.0 0.2 GO:0000109 nucleotide-excision repair complex(GO:0000109)
0.0 0.0 GO:0031312 extrinsic component of organelle membrane(GO:0031312)
0.0 0.3 GO:0046930 pore complex(GO:0046930)
0.0 0.7 GO:0030964 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0 0.1 GO:0005742 mitochondrial outer membrane translocase complex(GO:0005742)
0.0 0.1 GO:0042382 paraspeckles(GO:0042382)
0.0 0.0 GO:0000153 cytoplasmic ubiquitin ligase complex(GO:0000153)
0.0 0.2 GO:0017119 Golgi transport complex(GO:0017119)
0.0 0.0 GO:0045323 interleukin-1 receptor complex(GO:0045323)
0.0 0.1 GO:0034451 centriolar satellite(GO:0034451)
0.0 0.0 GO:0005577 fibrinogen complex(GO:0005577)
0.0 0.2 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.0 0.7 GO:0055037 recycling endosome(GO:0055037)
0.0 0.1 GO:0031258 lamellipodium membrane(GO:0031258)
0.0 0.1 GO:0000346 transcription export complex(GO:0000346)
0.0 0.1 GO:0035631 CD40 receptor complex(GO:0035631)
0.0 0.9 GO:0000786 nucleosome(GO:0000786)
0.0 0.3 GO:0031519 PcG protein complex(GO:0031519)
0.0 0.1 GO:0031080 nuclear pore outer ring(GO:0031080)
0.0 0.8 GO:0030027 lamellipodium(GO:0030027)
0.0 0.1 GO:0070461 SAGA-type complex(GO:0070461)
0.0 0.1 GO:0051233 spindle midzone(GO:0051233)
0.0 0.2 GO:0005884 actin filament(GO:0005884)
0.0 0.8 GO:0005643 nuclear pore(GO:0005643)
0.0 0.0 GO:0031010 ISWI-type complex(GO:0031010)
0.0 0.3 GO:0071339 MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339)
0.0 0.0 GO:0031205 endoplasmic reticulum Sec complex(GO:0031205)
0.0 0.2 GO:0005852 eukaryotic translation initiation factor 3 complex(GO:0005852)
0.0 0.1 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
0.0 0.1 GO:0005721 pericentric heterochromatin(GO:0005721)
0.0 0.1 GO:0030904 retromer complex(GO:0030904)
0.0 0.0 GO:0030008 TRAPP complex(GO:0030008)
0.0 0.1 GO:0005732 small nucleolar ribonucleoprotein complex(GO:0005732)
0.0 0.1 GO:0000803 sex chromosome(GO:0000803)
0.0 0.1 GO:0008180 COP9 signalosome(GO:0008180)
0.0 0.2 GO:0032153 cell division site(GO:0032153) cell division site part(GO:0032155)
0.0 0.1 GO:0016585 obsolete chromatin remodeling complex(GO:0016585)
0.0 0.0 GO:0000800 lateral element(GO:0000800)
0.0 0.0 GO:0016533 cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533)
0.0 0.4 GO:0016592 mediator complex(GO:0016592)
0.0 0.4 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 0.1 GO:0016461 unconventional myosin complex(GO:0016461)
0.0 0.1 GO:0034706 sodium channel complex(GO:0034706)
0.0 0.1 GO:0043198 dendritic shaft(GO:0043198)
0.0 1.0 GO:0008076 voltage-gated potassium channel complex(GO:0008076)
0.0 0.3 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)
0.0 0.0 GO:0005787 signal peptidase complex(GO:0005787)
0.0 0.0 GO:0001652 granular component(GO:0001652)
0.0 0.2 GO:0005763 organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.0 0.8 GO:0005938 cell cortex(GO:0005938)
0.0 0.1 GO:0044815 DNA packaging complex(GO:0044815)
0.0 0.2 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.0 0.1 GO:0005851 eukaryotic translation initiation factor 2B complex(GO:0005851)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 2.1 GO:0016493 C-C chemokine receptor activity(GO:0016493)
0.2 0.6 GO:0035184 histone threonine kinase activity(GO:0035184)
0.2 1.1 GO:0052813 phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) phosphatidylinositol bisphosphate kinase activity(GO:0052813)
0.2 0.6 GO:0004351 glutamate decarboxylase activity(GO:0004351)
0.2 0.5 GO:0004911 interleukin-2 receptor activity(GO:0004911)
0.1 0.4 GO:0004476 mannose-6-phosphate isomerase activity(GO:0004476)
0.1 0.4 GO:0003836 beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.1 0.3 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
0.1 0.2 GO:0052659 inositol-1,4,5-trisphosphate 5-phosphatase activity(GO:0052658) inositol-1,3,4,5-tetrakisphosphate 5-phosphatase activity(GO:0052659)
0.1 0.4 GO:0015925 galactosidase activity(GO:0015925)
0.1 0.3 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.1 0.8 GO:0050700 CARD domain binding(GO:0050700)
0.1 0.6 GO:0001609 G-protein coupled adenosine receptor activity(GO:0001609)
0.1 0.3 GO:0042608 T cell receptor binding(GO:0042608)
0.1 0.4 GO:0070492 oligosaccharide binding(GO:0070492)
0.1 0.3 GO:0070735 protein-glycine ligase activity(GO:0070735)
0.1 0.3 GO:0016309 1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
0.1 0.2 GO:0005134 interleukin-2 receptor binding(GO:0005134)
0.1 0.2 GO:0016312 inositol bisphosphate phosphatase activity(GO:0016312)
0.1 0.2 GO:0030368 interleukin-17 receptor activity(GO:0030368)
0.1 0.2 GO:0003987 acetate-CoA ligase activity(GO:0003987)
0.1 0.4 GO:0016494 C-X-C chemokine receptor activity(GO:0016494)
0.1 0.2 GO:0098599 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.1 0.2 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.1 0.2 GO:0047756 chondroitin 4-sulfotransferase activity(GO:0047756)
0.1 0.2 GO:0003876 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.1 0.4 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.1 0.2 GO:0015379 potassium:chloride symporter activity(GO:0015379)
0.1 0.1 GO:0033691 sialic acid binding(GO:0033691)
0.1 0.3 GO:0004046 aminoacylase activity(GO:0004046)
0.1 2.7 GO:0001948 glycoprotein binding(GO:0001948)
0.1 1.0 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.1 0.5 GO:0030332 cyclin binding(GO:0030332)
0.1 0.7 GO:0005031 tumor necrosis factor-activated receptor activity(GO:0005031)
0.1 0.2 GO:0047631 ADP-ribose diphosphatase activity(GO:0047631)
0.1 2.9 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.1 0.1 GO:0046030 inositol-polyphosphate 5-phosphatase activity(GO:0004445) inositol trisphosphate phosphatase activity(GO:0046030)
0.1 0.2 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.1 0.5 GO:0015278 calcium-release channel activity(GO:0015278) ligand-gated calcium channel activity(GO:0099604)
0.1 0.7 GO:0004697 protein kinase C activity(GO:0004697)
0.1 0.6 GO:0043425 bHLH transcription factor binding(GO:0043425)
0.1 0.4 GO:0050811 GABA receptor binding(GO:0050811)
0.1 0.5 GO:0030276 clathrin binding(GO:0030276)
0.1 0.4 GO:0004931 extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
0.1 0.3 GO:0004985 opioid receptor activity(GO:0004985)
0.1 0.3 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.1 0.2 GO:0003720 telomerase activity(GO:0003720) RNA-directed DNA polymerase activity(GO:0003964)
0.1 0.3 GO:0004563 beta-N-acetylhexosaminidase activity(GO:0004563)
0.1 0.9 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.1 0.4 GO:0004467 long-chain fatty acid-CoA ligase activity(GO:0004467)
0.1 0.2 GO:0008420 CTD phosphatase activity(GO:0008420)
0.1 0.2 GO:0004875 complement receptor activity(GO:0004875)
0.1 0.4 GO:0043014 alpha-tubulin binding(GO:0043014)
0.1 0.1 GO:0034237 protein kinase A regulatory subunit binding(GO:0034237)
0.1 0.2 GO:0008853 exodeoxyribonuclease III activity(GO:0008853)
0.1 0.4 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.0 0.1 GO:0031957 very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.0 0.1 GO:0004591 oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591)
0.0 0.3 GO:0008266 poly(U) RNA binding(GO:0008266)
0.0 0.2 GO:0005131 growth hormone receptor binding(GO:0005131)
0.0 0.3 GO:0004950 G-protein coupled chemoattractant receptor activity(GO:0001637) chemokine receptor activity(GO:0004950)
0.0 0.4 GO:0005522 profilin binding(GO:0005522)
0.0 0.3 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.0 0.1 GO:0042799 histone methyltransferase activity (H4-K20 specific)(GO:0042799)
0.0 0.1 GO:0004792 thiosulfate sulfurtransferase activity(GO:0004792)
0.0 0.2 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.0 0.2 GO:0047238 glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity(GO:0047238)
0.0 0.2 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.0 0.7 GO:0048487 beta-tubulin binding(GO:0048487)
0.0 0.2 GO:0030235 nitric-oxide synthase regulator activity(GO:0030235)
0.0 0.1 GO:0004465 lipoprotein lipase activity(GO:0004465)
0.0 0.6 GO:0004016 adenylate cyclase activity(GO:0004016)
0.0 0.5 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.0 0.1 GO:0004829 threonine-tRNA ligase activity(GO:0004829)
0.0 0.1 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.0 0.1 GO:0050698 proteoglycan sulfotransferase activity(GO:0050698)
0.0 0.2 GO:0016997 exo-alpha-sialidase activity(GO:0004308) alpha-sialidase activity(GO:0016997)
0.0 0.1 GO:0004582 dolichyl-phosphate beta-D-mannosyltransferase activity(GO:0004582)
0.0 0.2 GO:0005381 iron ion transmembrane transporter activity(GO:0005381)
0.0 0.0 GO:0001098 basal transcription machinery binding(GO:0001098) basal RNA polymerase II transcription machinery binding(GO:0001099)
0.0 0.1 GO:0016361 activin receptor activity, type I(GO:0016361)
0.0 0.1 GO:0070053 thrombospondin receptor activity(GO:0070053)
0.0 0.2 GO:0004064 arylesterase activity(GO:0004064)
0.0 0.1 GO:0016842 amidine-lyase activity(GO:0016842)
0.0 0.1 GO:0043533 inositol 1,3,4,5 tetrakisphosphate binding(GO:0043533)
0.0 0.1 GO:0050508 glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0050508)
0.0 0.1 GO:0008296 3'-5'-exodeoxyribonuclease activity(GO:0008296)
0.0 0.2 GO:0004126 cytidine deaminase activity(GO:0004126)
0.0 0.7 GO:0043621 protein self-association(GO:0043621)
0.0 0.3 GO:0035251 UDP-glucosyltransferase activity(GO:0035251)
0.0 0.2 GO:0001012 RNA polymerase II regulatory region sequence-specific DNA binding(GO:0000977) RNA polymerase II regulatory region DNA binding(GO:0001012)
0.0 0.3 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.0 0.4 GO:0070064 proline-rich region binding(GO:0070064)
0.0 0.2 GO:0042834 peptidoglycan binding(GO:0042834)
0.0 0.3 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.0 0.1 GO:0008109 N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109)
0.0 0.2 GO:0031491 nucleosome binding(GO:0031491)
0.0 0.1 GO:0004449 isocitrate dehydrogenase (NAD+) activity(GO:0004449)
0.0 0.1 GO:0098518 polynucleotide phosphatase activity(GO:0098518)
0.0 0.2 GO:0019992 diacylglycerol binding(GO:0019992)
0.0 0.2 GO:0005314 high-affinity glutamate transmembrane transporter activity(GO:0005314)
0.0 0.1 GO:0019788 NEDD8 transferase activity(GO:0019788)
0.0 0.4 GO:0000155 phosphorelay sensor kinase activity(GO:0000155)
0.0 0.1 GO:0035197 siRNA binding(GO:0035197)
0.0 0.1 GO:0001591 dopamine neurotransmitter receptor activity, coupled via Gi/Go(GO:0001591)
0.0 0.1 GO:0004897 ciliary neurotrophic factor receptor activity(GO:0004897)
0.0 0.2 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.0 0.4 GO:0016888 endodeoxyribonuclease activity, producing 5'-phosphomonoesters(GO:0016888)
0.0 1.3 GO:0004896 cytokine receptor activity(GO:0004896)
0.0 0.2 GO:0016308 1-phosphatidylinositol-4-phosphate 5-kinase activity(GO:0016308)
0.0 0.0 GO:0034236 protein kinase A catalytic subunit binding(GO:0034236)
0.0 0.2 GO:0015165 pyrimidine nucleotide-sugar transmembrane transporter activity(GO:0015165)
0.0 0.1 GO:0008545 JUN kinase kinase activity(GO:0008545)
0.0 0.1 GO:0008332 low voltage-gated calcium channel activity(GO:0008332)
0.0 0.1 GO:0004802 transketolase activity(GO:0004802)
0.0 0.1 GO:0008649 rRNA methyltransferase activity(GO:0008649)
0.0 0.5 GO:0035064 methylated histone binding(GO:0035064)
0.0 0.3 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.0 0.1 GO:0004517 nitric-oxide synthase activity(GO:0004517)
0.0 0.1 GO:0005000 vasopressin receptor activity(GO:0005000)
0.0 0.5 GO:0008373 sialyltransferase activity(GO:0008373)
0.0 0.4 GO:0005487 nucleocytoplasmic transporter activity(GO:0005487)
0.0 0.1 GO:0034481 chondroitin sulfotransferase activity(GO:0034481)
0.0 0.1 GO:0046975 histone methyltransferase activity (H3-K36 specific)(GO:0046975)
0.0 0.1 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.0 0.3 GO:0046875 ephrin receptor binding(GO:0046875)
0.0 0.1 GO:0008035 high-density lipoprotein particle binding(GO:0008035)
0.0 0.4 GO:0005527 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.0 0.3 GO:0005095 GTPase inhibitor activity(GO:0005095)
0.0 0.2 GO:0046920 alpha-(1->3)-fucosyltransferase activity(GO:0046920)
0.0 0.2 GO:0031701 angiotensin receptor binding(GO:0031701)
0.0 0.3 GO:0001619 obsolete lysosphingolipid and lysophosphatidic acid receptor activity(GO:0001619)
0.0 0.1 GO:0043024 ribosomal small subunit binding(GO:0043024)
0.0 0.2 GO:0048531 beta-1,3-galactosyltransferase activity(GO:0048531)
0.0 0.2 GO:0004703 G-protein coupled receptor kinase activity(GO:0004703)
0.0 0.1 GO:0004994 somatostatin receptor activity(GO:0004994)
0.0 0.4 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.0 0.1 GO:0016715 dopamine beta-monooxygenase activity(GO:0004500) oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen(GO:0016715)
0.0 0.8 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.0 0.2 GO:0015288 porin activity(GO:0015288)
0.0 0.1 GO:0046404 ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity(GO:0046404) polydeoxyribonucleotide kinase activity(GO:0051733) ATP-dependent polynucleotide kinase activity(GO:0051734)
0.0 0.2 GO:0050431 transforming growth factor beta binding(GO:0050431)
0.0 0.3 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.0 0.1 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.0 0.0 GO:0005127 ciliary neurotrophic factor receptor binding(GO:0005127)
0.0 0.1 GO:0004047 aminomethyltransferase activity(GO:0004047)
0.0 0.0 GO:0017002 activin-activated receptor activity(GO:0017002)
0.0 0.0 GO:0042166 acetylcholine binding(GO:0042166)
0.0 2.9 GO:0003702 obsolete RNA polymerase II transcription factor activity(GO:0003702)
0.0 0.1 GO:0004704 NF-kappaB-inducing kinase activity(GO:0004704)
0.0 1.3 GO:0008301 DNA binding, bending(GO:0008301)
0.0 0.1 GO:0016857 racemase and epimerase activity, acting on carbohydrates and derivatives(GO:0016857)
0.0 0.1 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.0 0.1 GO:0016208 AMP binding(GO:0016208)
0.0 0.1 GO:0004514 nicotinate-nucleotide diphosphorylase (carboxylating) activity(GO:0004514)
0.0 0.1 GO:0004972 NMDA glutamate receptor activity(GO:0004972)
0.0 0.1 GO:0015038 glutathione disulfide oxidoreductase activity(GO:0015038)
0.0 0.5 GO:0001608 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.0 0.4 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.0 0.1 GO:0042910 xenobiotic-transporting ATPase activity(GO:0008559) xenobiotic transporter activity(GO:0042910)
0.0 0.4 GO:0004889 acetylcholine-activated cation-selective channel activity(GO:0004889)
0.0 0.0 GO:0015018 galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity(GO:0015018)
0.0 0.1 GO:0005111 type 2 fibroblast growth factor receptor binding(GO:0005111)
0.0 0.1 GO:0004032 alditol:NADP+ 1-oxidoreductase activity(GO:0004032)
0.0 0.0 GO:0002060 purine nucleobase binding(GO:0002060)
0.0 0.1 GO:0030881 beta-2-microglobulin binding(GO:0030881)
0.0 0.1 GO:0004142 diacylglycerol cholinephosphotransferase activity(GO:0004142)
0.0 0.6 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.0 0.1 GO:0016728 ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
0.0 0.1 GO:0071208 histone pre-mRNA DCP binding(GO:0071208)
0.0 0.1 GO:0001727 lipid kinase activity(GO:0001727)
0.0 0.1 GO:0004427 inorganic diphosphatase activity(GO:0004427)
0.0 0.0 GO:0042289 MHC class II protein binding(GO:0042289)
0.0 0.1 GO:0008475 procollagen-lysine 5-dioxygenase activity(GO:0008475)
0.0 0.1 GO:0004949 cannabinoid receptor activity(GO:0004949)
0.0 0.0 GO:0051731 polynucleotide 5'-hydroxyl-kinase activity(GO:0051731)
0.0 0.0 GO:0008241 peptidyl-dipeptidase activity(GO:0008241)
0.0 0.1 GO:0005176 ErbB-2 class receptor binding(GO:0005176)
0.0 0.0 GO:0043008 ATP-dependent protein binding(GO:0043008)
0.0 0.1 GO:0016774 phosphotransferase activity, carboxyl group as acceptor(GO:0016774)
0.0 0.1 GO:0005346 purine ribonucleotide transmembrane transporter activity(GO:0005346)
0.0 0.1 GO:0004999 vasoactive intestinal polypeptide receptor activity(GO:0004999)
0.0 0.1 GO:0033300 dehydroascorbic acid transporter activity(GO:0033300)
0.0 0.0 GO:0004516 nicotinate phosphoribosyltransferase activity(GO:0004516)
0.0 0.1 GO:0019239 deaminase activity(GO:0019239)
0.0 0.1 GO:0004957 prostaglandin E receptor activity(GO:0004957)
0.0 0.2 GO:0070491 repressing transcription factor binding(GO:0070491)
0.0 0.2 GO:0008171 O-methyltransferase activity(GO:0008171)
0.0 0.1 GO:0030292 protein tyrosine kinase inhibitor activity(GO:0030292)
0.0 0.1 GO:0035241 protein-arginine omega-N monomethyltransferase activity(GO:0035241)
0.0 0.4 GO:0016814 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines(GO:0016814)
0.0 0.1 GO:0004396 hexokinase activity(GO:0004396)
0.0 0.1 GO:0004967 glucagon receptor activity(GO:0004967)
0.0 0.1 GO:0032552 deoxyribonucleotide binding(GO:0032552)
0.0 0.1 GO:0004966 galanin receptor activity(GO:0004966)
0.0 0.2 GO:0032813 tumor necrosis factor receptor superfamily binding(GO:0032813)
0.0 0.1 GO:0015215 nucleotide transmembrane transporter activity(GO:0015215)
0.0 0.0 GO:0004955 prostaglandin receptor activity(GO:0004955)
0.0 0.0 GO:0004954 prostanoid receptor activity(GO:0004954)
0.0 0.1 GO:0003785 actin monomer binding(GO:0003785)
0.0 0.1 GO:0015347 sodium-independent organic anion transmembrane transporter activity(GO:0015347)
0.0 0.4 GO:0004114 3',5'-cyclic-nucleotide phosphodiesterase activity(GO:0004114)
0.0 0.5 GO:0042393 histone binding(GO:0042393)
0.0 0.1 GO:0000739 obsolete DNA strand annealing activity(GO:0000739)
0.0 0.4 GO:0003725 double-stranded RNA binding(GO:0003725)
0.0 0.4 GO:0004177 aminopeptidase activity(GO:0004177)
0.0 0.1 GO:0008517 folic acid transporter activity(GO:0008517)
0.0 0.5 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.0 0.0 GO:0016744 transferase activity, transferring aldehyde or ketonic groups(GO:0016744)
0.0 0.7 GO:0050136 NADH dehydrogenase activity(GO:0003954) NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0 0.1 GO:0003847 1-alkyl-2-acetylglycerophosphocholine esterase activity(GO:0003847)
0.0 0.1 GO:0017080 sodium channel regulator activity(GO:0017080)
0.0 0.1 GO:0004614 phosphoglucomutase activity(GO:0004614)
0.0 0.1 GO:0050815 phosphoserine binding(GO:0050815)
0.0 0.1 GO:0031435 mitogen-activated protein kinase kinase kinase binding(GO:0031435)
0.0 0.1 GO:0019136 deoxynucleoside kinase activity(GO:0019136)
0.0 0.1 GO:0030544 Hsp70 protein binding(GO:0030544)
0.0 0.1 GO:0000400 four-way junction DNA binding(GO:0000400)
0.0 0.1 GO:0050544 arachidonic acid binding(GO:0050544)
0.0 0.1 GO:0016595 glutamate binding(GO:0016595)
0.0 0.0 GO:0050510 N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity(GO:0050510)
0.0 0.2 GO:0031593 polyubiquitin binding(GO:0031593)
0.0 0.2 GO:0005246 calcium channel regulator activity(GO:0005246)
0.0 0.0 GO:0004311 farnesyltranstransferase activity(GO:0004311)
0.0 0.4 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.0 0.1 GO:0043522 leucine zipper domain binding(GO:0043522)
0.0 0.2 GO:0005548 phospholipid transporter activity(GO:0005548)
0.0 0.1 GO:0034593 phosphatidylinositol bisphosphate phosphatase activity(GO:0034593)
0.0 0.0 GO:0004814 arginine-tRNA ligase activity(GO:0004814)
0.0 0.1 GO:0016778 diphosphotransferase activity(GO:0016778)
0.0 0.1 GO:0001085 RNA polymerase II transcription factor binding(GO:0001085)
0.0 0.1 GO:0070087 chromo shadow domain binding(GO:0070087)
0.0 0.0 GO:0000064 L-ornithine transmembrane transporter activity(GO:0000064)
0.0 0.0 GO:0071723 lipopeptide binding(GO:0071723)
0.0 0.0 GO:0048156 tau protein binding(GO:0048156)
0.0 0.0 GO:0016303 1-phosphatidylinositol-3-kinase activity(GO:0016303)
0.0 0.3 GO:0051219 phosphoprotein binding(GO:0051219)
0.0 0.1 GO:0070579 methylcytosine dioxygenase activity(GO:0070579)
0.0 0.0 GO:0031849 olfactory receptor binding(GO:0031849)
0.0 0.0 GO:0004706 JUN kinase kinase kinase activity(GO:0004706)
0.0 0.5 GO:0019903 protein phosphatase binding(GO:0019903)
0.0 0.0 GO:0004774 succinate-CoA ligase activity(GO:0004774)
0.0 0.1 GO:0031996 thioesterase binding(GO:0031996)
0.0 0.1 GO:0070513 death domain binding(GO:0070513)
0.0 0.2 GO:0008601 protein phosphatase type 2A regulator activity(GO:0008601)
0.0 0.0 GO:0005275 amine transmembrane transporter activity(GO:0005275)
0.0 0.1 GO:0004459 L-lactate dehydrogenase activity(GO:0004459)
0.0 0.1 GO:0003688 DNA replication origin binding(GO:0003688)
0.0 0.0 GO:0004607 phosphatidylcholine-sterol O-acyltransferase activity(GO:0004607)
0.0 0.4 GO:0001104 transcription factor activity, RNA polymerase II transcription factor binding(GO:0001076) RNA polymerase II transcription cofactor activity(GO:0001104)
0.0 0.0 GO:0050693 LBD domain binding(GO:0050693)
0.0 0.2 GO:0016846 carbon-sulfur lyase activity(GO:0016846)
0.0 0.1 GO:0030229 very-low-density lipoprotein particle receptor activity(GO:0030229)
0.0 0.2 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.0 0.1 GO:0070567 cytidylyltransferase activity(GO:0070567)
0.0 0.0 GO:0008469 histone-arginine N-methyltransferase activity(GO:0008469)
0.0 0.1 GO:0048018 receptor agonist activity(GO:0048018)
0.0 0.1 GO:0043208 glycosphingolipid binding(GO:0043208)
0.0 0.0 GO:0000268 peroxisome targeting sequence binding(GO:0000268)
0.0 0.8 GO:0004221 obsolete ubiquitin thiolesterase activity(GO:0004221)
0.0 0.1 GO:0016934 extracellular-glycine-gated ion channel activity(GO:0016933) extracellular-glycine-gated chloride channel activity(GO:0016934)
0.0 0.1 GO:0003709 obsolete RNA polymerase III transcription factor activity(GO:0003709)
0.0 0.4 GO:0017137 Rab GTPase binding(GO:0017137)
0.0 0.3 GO:0016676 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors(GO:0016675) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 0.0 GO:0004980 melanocyte-stimulating hormone receptor activity(GO:0004980)
0.0 0.1 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0 0.0 GO:0070095 fructose-6-phosphate binding(GO:0070095)
0.0 0.1 GO:0030515 snoRNA binding(GO:0030515)
0.0 0.1 GO:0030275 LRR domain binding(GO:0030275)
0.0 0.7 GO:0016410 N-acyltransferase activity(GO:0016410)
0.0 0.3 GO:0000149 SNARE binding(GO:0000149)
0.0 0.1 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.0 0.1 GO:0070742 C2H2 zinc finger domain binding(GO:0070742)
0.0 0.1 GO:0030296 protein tyrosine kinase activator activity(GO:0030296)
0.0 0.1 GO:0004428 obsolete inositol or phosphatidylinositol kinase activity(GO:0004428)
0.0 0.0 GO:0004321 fatty-acyl-CoA synthase activity(GO:0004321)
0.0 0.2 GO:0009881 photoreceptor activity(GO:0009881)
0.0 0.1 GO:0005521 lamin binding(GO:0005521)
0.0 0.0 GO:0050265 RNA uridylyltransferase activity(GO:0050265)
0.0 0.0 GO:0016986 obsolete transcription initiation factor activity(GO:0016986)
0.0 0.0 GO:0016922 ligand-dependent nuclear receptor binding(GO:0016922)
0.0 0.0 GO:0004673 protein histidine kinase activity(GO:0004673)
0.0 0.1 GO:0070888 E-box binding(GO:0070888)
0.0 0.2 GO:0005231 excitatory extracellular ligand-gated ion channel activity(GO:0005231)
0.0 0.2 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435)
0.0 0.3 GO:0051087 chaperone binding(GO:0051087)
0.0 0.0 GO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.0 2.6 GO:0030695 GTPase regulator activity(GO:0030695)
0.0 0.1 GO:0017091 AU-rich element binding(GO:0017091)
0.0 0.3 GO:0004693 cyclin-dependent protein serine/threonine kinase activity(GO:0004693) cyclin-dependent protein kinase activity(GO:0097472)
0.0 0.8 GO:0017124 SH3 domain binding(GO:0017124)
0.0 0.1 GO:0015464 acetylcholine receptor activity(GO:0015464)
0.0 0.1 GO:0005499 vitamin D binding(GO:0005499)
0.0 0.0 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.0 0.0 GO:0002054 nucleobase binding(GO:0002054)
0.0 0.0 GO:0008192 RNA guanylyltransferase activity(GO:0008192)
0.0 0.5 GO:0004725 protein tyrosine phosphatase activity(GO:0004725)
0.0 0.0 GO:0019956 chemokine binding(GO:0019956)
0.0 0.1 GO:0046912 transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
0.0 0.2 GO:0019843 rRNA binding(GO:0019843)
0.0 0.0 GO:0003918 DNA topoisomerase type II (ATP-hydrolyzing) activity(GO:0003918) DNA topoisomerase II activity(GO:0061505)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 5.6 PID CD8 TCR PATHWAY TCR signaling in naïve CD8+ T cells
0.1 1.2 SA PTEN PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.1 1.4 PID TCR PATHWAY TCR signaling in naïve CD4+ T cells
0.1 0.1 PID S1P S1P4 PATHWAY S1P4 pathway
0.1 1.4 PID IL2 STAT5 PATHWAY IL2 signaling events mediated by STAT5
0.1 0.9 PID LPA4 PATHWAY LPA4-mediated signaling events
0.1 0.3 PID TCR RAS PATHWAY Ras signaling in the CD4+ TCR pathway
0.1 0.2 PID IL8 CXCR1 PATHWAY IL8- and CXCR1-mediated signaling events
0.0 0.0 PID PI3KCI AKT PATHWAY Class I PI3K signaling events mediated by Akt
0.0 0.3 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.0 0.7 PID BETA CATENIN DEG PATHWAY Degradation of beta catenin
0.0 0.6 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0 1.8 PID NFAT 3PATHWAY Role of Calcineurin-dependent NFAT signaling in lymphocytes
0.0 0.3 SIG PIP3 SIGNALING IN B LYMPHOCYTES Genes related to PIP3 signaling in B lymphocytes
0.0 1.3 PID ECADHERIN NASCENT AJ PATHWAY E-cadherin signaling in the nascent adherens junction
0.0 0.0 PID CXCR3 PATHWAY CXCR3-mediated signaling events
0.0 0.7 PID EPHRINB REV PATHWAY Ephrin B reverse signaling
0.0 0.2 SA TRKA RECEPTOR The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth.
0.0 0.9 PID IL8 CXCR2 PATHWAY IL8- and CXCR2-mediated signaling events
0.0 1.1 PID PI3KCI PATHWAY Class I PI3K signaling events
0.0 0.7 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.0 0.1 ST DIFFERENTIATION PATHWAY IN PC12 CELLS Differentiation Pathway in PC12 Cells; this is a specific case of PAC1 Receptor Pathway.
0.0 0.1 SA FAS SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.0 0.4 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4
0.0 1.0 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0 0.2 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL
0.0 0.3 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.0 0.4 PID P38 ALPHA BETA PATHWAY Regulation of p38-alpha and p38-beta
0.0 1.5 PID BETA CATENIN NUC PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription
0.0 0.2 PID GMCSF PATHWAY GMCSF-mediated signaling events
0.0 0.5 PID BCR 5PATHWAY BCR signaling pathway
0.0 0.6 PID KIT PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
0.0 0.6 PID THROMBIN PAR1 PATHWAY PAR1-mediated thrombin signaling events
0.0 0.3 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.0 0.5 PID CD8 TCR DOWNSTREAM PATHWAY Downstream signaling in naïve CD8+ T cells
0.0 0.5 PID ERBB1 INTERNALIZATION PATHWAY Internalization of ErbB1
0.0 0.7 PID CERAMIDE PATHWAY Ceramide signaling pathway
0.0 0.6 PID INTEGRIN CS PATHWAY Integrin family cell surface interactions
0.0 0.5 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.0 0.0 PID SYNDECAN 1 PATHWAY Syndecan-1-mediated signaling events
0.0 0.3 PID TXA2PATHWAY Thromboxane A2 receptor signaling
0.0 0.1 ST IL 13 PATHWAY Interleukin 13 (IL-13) Pathway
0.0 0.2 PID CD40 PATHWAY CD40/CD40L signaling
0.0 0.4 PID HIF2PATHWAY HIF-2-alpha transcription factor network
0.0 0.3 SIG BCR SIGNALING PATHWAY Members of the BCR signaling pathway
0.0 0.1 PID RANBP2 PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.0 0.4 PID IL12 2PATHWAY IL12-mediated signaling events
0.0 0.2 PID WNT CANONICAL PATHWAY Canonical Wnt signaling pathway
0.0 0.1 PID IL27 PATHWAY IL27-mediated signaling events
0.0 0.2 PID DNA PK PATHWAY DNA-PK pathway in nonhomologous end joining
0.0 0.1 PID NFKAPPAB CANONICAL PATHWAY Canonical NF-kappaB pathway
0.0 0.3 PID RAS PATHWAY Regulation of Ras family activation
0.0 0.3 PID HEDGEHOG GLI PATHWAY Hedgehog signaling events mediated by Gli proteins
0.0 0.1 PID IL2 1PATHWAY IL2-mediated signaling events
0.0 0.1 PID IL6 7 PATHWAY IL6-mediated signaling events
0.0 0.5 PID AR TF PATHWAY Regulation of Androgen receptor activity
0.0 0.4 PID LKB1 PATHWAY LKB1 signaling events
0.0 0.1 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
0.0 0.1 PID IL23 PATHWAY IL23-mediated signaling events
0.0 0.2 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.0 0.7 PID SMAD2 3NUCLEAR PATHWAY Regulation of nuclear SMAD2/3 signaling
0.0 0.0 PID IL5 PATHWAY IL5-mediated signaling events
0.0 0.5 PID ERA GENOMIC PATHWAY Validated nuclear estrogen receptor alpha network
0.0 0.3 PID TELOMERASE PATHWAY Regulation of Telomerase
0.0 0.2 PID RB 1PATHWAY Regulation of retinoblastoma protein
0.0 0.0 PID EPHA2 FWD PATHWAY EPHA2 forward signaling
0.0 0.1 PID MYC PATHWAY C-MYC pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.8 REACTOME BINDING AND ENTRY OF HIV VIRION Genes involved in Binding and entry of HIV virion
0.2 0.6 REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.1 1.3 REACTOME PECAM1 INTERACTIONS Genes involved in PECAM1 interactions
0.1 0.5 REACTOME DAG AND IP3 SIGNALING Genes involved in DAG and IP3 signaling
0.1 2.3 REACTOME GENERATION OF SECOND MESSENGER MOLECULES Genes involved in Generation of second messenger molecules
0.1 2.2 REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.1 2.1 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.1 0.1 REACTOME PROSTACYCLIN SIGNALLING THROUGH PROSTACYCLIN RECEPTOR Genes involved in Prostacyclin signalling through prostacyclin receptor
0.1 0.7 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.1 0.6 REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY Genes involved in Adenylate cyclase activating pathway
0.1 0.5 REACTOME PKA MEDIATED PHOSPHORYLATION OF CREB Genes involved in PKA-mediated phosphorylation of CREB
0.1 0.3 REACTOME COSTIMULATION BY THE CD28 FAMILY Genes involved in Costimulation by the CD28 family
0.1 0.9 REACTOME G ALPHA Z SIGNALLING EVENTS Genes involved in G alpha (z) signalling events
0.1 0.2 REACTOME EGFR DOWNREGULATION Genes involved in EGFR downregulation
0.0 0.0 REACTOME ENDOSOMAL VACUOLAR PATHWAY Genes involved in Endosomal/Vacuolar pathway
0.0 0.2 REACTOME IRAK1 RECRUITS IKK COMPLEX Genes involved in IRAK1 recruits IKK complex
0.0 0.1 REACTOME REGULATION OF SIGNALING BY CBL Genes involved in Regulation of signaling by CBL
0.0 0.5 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.0 1.1 REACTOME G BETA GAMMA SIGNALLING THROUGH PI3KGAMMA Genes involved in G beta:gamma signalling through PI3Kgamma
0.0 0.6 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.0 0.5 REACTOME PROLACTIN RECEPTOR SIGNALING Genes involved in Prolactin receptor signaling
0.0 1.1 REACTOME IL 2 SIGNALING Genes involved in Interleukin-2 signaling
0.0 0.9 REACTOME THE ROLE OF NEF IN HIV1 REPLICATION AND DISEASE PATHOGENESIS Genes involved in The role of Nef in HIV-1 replication and disease pathogenesis
0.0 0.1 REACTOME PD1 SIGNALING Genes involved in PD-1 signaling
0.0 0.7 REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION Genes involved in GABA synthesis, release, reuptake and degradation
0.0 0.2 REACTOME INFLAMMASOMES Genes involved in Inflammasomes
0.0 0.5 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.0 0.4 REACTOME RAP1 SIGNALLING Genes involved in Rap1 signalling
0.0 0.3 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
0.0 0.2 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.0 1.9 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0 0.2 REACTOME SPRY REGULATION OF FGF SIGNALING Genes involved in Spry regulation of FGF signaling
0.0 0.4 REACTOME HIGHLY CALCIUM PERMEABLE POSTSYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Highly calcium permeable postsynaptic nicotinic acetylcholine receptors
0.0 0.2 REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY Genes involved in Regulation of the Fanconi anemia pathway
0.0 0.4 REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR Genes involved in Trafficking and processing of endosomal TLR
0.0 0.3 REACTOME TAK1 ACTIVATES NFKB BY PHOSPHORYLATION AND ACTIVATION OF IKKS COMPLEX Genes involved in TAK1 activates NFkB by phosphorylation and activation of IKKs complex
0.0 0.2 REACTOME CTLA4 INHIBITORY SIGNALING Genes involved in CTLA4 inhibitory signaling
0.0 0.4 REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.0 0.3 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.0 0.5 REACTOME NUCLEOTIDE LIKE PURINERGIC RECEPTORS Genes involved in Nucleotide-like (purinergic) receptors
0.0 0.0 REACTOME INFLUENZA LIFE CYCLE Genes involved in Influenza Life Cycle
0.0 0.1 REACTOME REGULATION OF INSULIN SECRETION BY GLUCAGON LIKE PEPTIDE1 Genes involved in Regulation of Insulin Secretion by Glucagon-like Peptide-1
0.0 0.1 REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
0.0 0.6 REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE Genes involved in Synthesis of PIPs at the plasma membrane
0.0 0.2 REACTOME REGULATION OF KIT SIGNALING Genes involved in Regulation of KIT signaling
0.0 0.5 REACTOME TRANSPORT TO THE GOLGI AND SUBSEQUENT MODIFICATION Genes involved in Transport to the Golgi and subsequent modification
0.0 0.4 REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.0 0.3 REACTOME OPSINS Genes involved in Opsins
0.0 0.0 REACTOME SCF BETA TRCP MEDIATED DEGRADATION OF EMI1 Genes involved in SCF-beta-TrCP mediated degradation of Emi1
0.0 1.4 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.0 0.2 REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Glutamate Neurotransmitter Release Cycle
0.0 0.5 REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.0 0.7 REACTOME TRANSPORT OF RIBONUCLEOPROTEINS INTO THE HOST NUCLEUS Genes involved in Transport of Ribonucleoproteins into the Host Nucleus
0.0 0.3 REACTOME ASSOCIATION OF LICENSING FACTORS WITH THE PRE REPLICATIVE COMPLEX Genes involved in Association of licensing factors with the pre-replicative complex
0.0 1.0 REACTOME GLYCOSPHINGOLIPID METABOLISM Genes involved in Glycosphingolipid metabolism
0.0 0.4 REACTOME ENOS ACTIVATION AND REGULATION Genes involved in eNOS activation and regulation
0.0 0.5 REACTOME PRE NOTCH TRANSCRIPTION AND TRANSLATION Genes involved in Pre-NOTCH Transcription and Translation
0.0 2.0 REACTOME RESPIRATORY ELECTRON TRANSPORT ATP SYNTHESIS BY CHEMIOSMOTIC COUPLING AND HEAT PRODUCTION BY UNCOUPLING PROTEINS Genes involved in Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins.
0.0 0.1 REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX UPON TLR7 8 OR 9 STIMULATION Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
0.0 0.1 REACTOME PHOSPHOLIPASE C MEDIATED CASCADE Genes involved in Phospholipase C-mediated cascade
0.0 0.2 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.0 0.7 REACTOME SIGNALING BY SCF KIT Genes involved in Signaling by SCF-KIT
0.0 0.2 REACTOME DSCAM INTERACTIONS Genes involved in DSCAM interactions
0.0 1.0 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.0 0.8 REACTOME G ALPHA1213 SIGNALLING EVENTS Genes involved in G alpha (12/13) signalling events
0.0 0.1 REACTOME SCFSKP2 MEDIATED DEGRADATION OF P27 P21 Genes involved in SCF(Skp2)-mediated degradation of p27/p21
0.0 0.2 REACTOME PROSTANOID LIGAND RECEPTORS Genes involved in Prostanoid ligand receptors
0.0 0.3 REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.0 0.3 REACTOME CREB PHOSPHORYLATION THROUGH THE ACTIVATION OF RAS Genes involved in CREB phosphorylation through the activation of Ras
0.0 0.8 REACTOME INTERFERON GAMMA SIGNALING Genes involved in Interferon gamma signaling
0.0 0.2 REACTOME DOWNSTREAM TCR SIGNALING Genes involved in Downstream TCR signaling
0.0 0.4 REACTOME G1 PHASE Genes involved in G1 Phase
0.0 0.4 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.0 0.4 REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.0 0.3 REACTOME INTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Intrinsic Pathway for Apoptosis
0.0 0.2 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
0.0 0.8 REACTOME VIF MEDIATED DEGRADATION OF APOBEC3G Genes involved in Vif-mediated degradation of APOBEC3G
0.0 0.1 REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS Genes involved in Membrane binding and targetting of GAG proteins
0.0 0.1 REACTOME P38MAPK EVENTS Genes involved in p38MAPK events
0.0 0.3 REACTOME CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
0.0 0.1 REACTOME TRAF6 MEDIATED NFKB ACTIVATION Genes involved in TRAF6 mediated NF-kB activation
0.0 0.6 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.0 0.0 REACTOME MITOTIC M M G1 PHASES Genes involved in Mitotic M-M/G1 phases
0.0 0.4 REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.0 0.3 REACTOME CHONDROITIN SULFATE BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
0.0 0.2 REACTOME VIRAL MESSENGER RNA SYNTHESIS Genes involved in Viral Messenger RNA Synthesis
0.0 0.1 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.0 0.2 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.0 0.6 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.0 0.1 REACTOME ABORTIVE ELONGATION OF HIV1 TRANSCRIPT IN THE ABSENCE OF TAT Genes involved in Abortive elongation of HIV-1 transcript in the absence of Tat
0.0 1.0 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.0 0.0 REACTOME ARMS MEDIATED ACTIVATION Genes involved in ARMS-mediated activation
0.0 0.2 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.0 0.2 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.0 0.0 REACTOME POST NMDA RECEPTOR ACTIVATION EVENTS Genes involved in Post NMDA receptor activation events
0.0 0.0 REACTOME DESTABILIZATION OF MRNA BY KSRP Genes involved in Destabilization of mRNA by KSRP
0.0 0.1 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor
0.0 0.0 REACTOME CYCLIN E ASSOCIATED EVENTS DURING G1 S TRANSITION Genes involved in Cyclin E associated events during G1/S transition
0.0 0.3 REACTOME REGULATION OF BETA CELL DEVELOPMENT Genes involved in Regulation of beta-cell development
0.0 0.2 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.0 0.0 REACTOME G2 M DNA DAMAGE CHECKPOINT Genes involved in G2/M DNA damage checkpoint
0.0 0.0 REACTOME DESTABILIZATION OF MRNA BY AUF1 HNRNP D0 Genes involved in Destabilization of mRNA by AUF1 (hnRNP D0)
0.0 0.3 REACTOME REGULATION OF INSULIN SECRETION Genes involved in Regulation of Insulin Secretion
0.0 0.3 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.0 0.2 REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.0 0.1 REACTOME ABACAVIR TRANSPORT AND METABOLISM Genes involved in Abacavir transport and metabolism
0.0 0.2 REACTOME PYRUVATE METABOLISM Genes involved in Pyruvate metabolism
0.0 0.0 REACTOME PEPTIDE CHAIN ELONGATION Genes involved in Peptide chain elongation
0.0 0.0 REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
0.0 0.1 REACTOME MRNA CAPPING Genes involved in mRNA Capping
0.0 0.1 REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING Genes involved in Downregulation of TGF-beta receptor signaling
0.0 0.1 REACTOME NONSENSE MEDIATED DECAY ENHANCED BY THE EXON JUNCTION COMPLEX Genes involved in Nonsense Mediated Decay Enhanced by the Exon Junction Complex
0.0 0.1 REACTOME G0 AND EARLY G1 Genes involved in G0 and Early G1
0.0 0.2 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.0 0.4 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import
0.0 0.2 REACTOME BOTULINUM NEUROTOXICITY Genes involved in Botulinum neurotoxicity
0.0 0.2 REACTOME ENERGY DEPENDENT REGULATION OF MTOR BY LKB1 AMPK Genes involved in Energy dependent regulation of mTOR by LKB1-AMPK
0.0 0.1 REACTOME SEROTONIN RECEPTORS Genes involved in Serotonin receptors
0.0 0.3 REACTOME EXTENSION OF TELOMERES Genes involved in Extension of Telomeres
0.0 0.3 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins
0.0 0.2 REACTOME METABOLISM OF NON CODING RNA Genes involved in Metabolism of non-coding RNA
0.0 0.0 REACTOME PHOSPHORYLATION OF THE APC C Genes involved in Phosphorylation of the APC/C