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ENCODE: H3K4me1 ChIP-Seq of primary human cells

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CREMA is a free online tool that recognizes most important transcription factors that change the chromatin state across different samples.

Results for PRDM1

Z-value: 0.92

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Transcription factors associated with PRDM1

Gene Symbol	Gene ID	Gene Info
PRDM1 Ensembl NCBI GeneCards UniProt	ENSG00000057657.10	PRDM1

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE	Gene	Distance	Association probability	Pearson corr. coef.	P-value	Plot
PRDM1	chr6_106531939_106532090	2181	0.368216	0.62	7.4e-02	Click!
PRDM1	chr6_106532092_106532808	1745	0.425000	0.58	1.0e-01	Click!
PRDM1	chr6_106536990_106537141	1610	0.443934	0.54	1.3e-01	Click!
PRDM1	chr6_106534185_106534428	111	0.974765	-0.53	1.4e-01	Click!
PRDM1	chr6_106531528_106531679	2592	0.333925	0.51	1.6e-01	Click!

Activity of the PRDM1 motif across conditions

Conditions sorted by the z-value of the PRDM1 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE)	Target Score	Top associated gene	Gene Info	Distance of CRE to TSS	CRE/Gene association probability
chr4_81102558_81102775	0.29	PRDM8	PR domain containing 8	2773	0.3
chr20_37055414_37055565	0.28	ENSG00000225091	.	596	0.49
chr17_64669218_64669401	0.28	AC006947.1		3181	0.27
chr1_16250578_16250729	0.28	ENSG00000238818	.	13261	0.14
chr22_37456995_37457146	0.27	ENSG00000201078	.	5683	0.11
chr21_38782714_38782865	0.26	DYRK1A	dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A	8418	0.24
chr7_55253756_55253907	0.26	EGFR-AS1	EGFR antisense RNA 1	2796	0.38
chr21_46891130_46891304	0.25	COL18A1	collagen, type XVIII, alpha 1	15793	0.18
chr3_176759869_176760020	0.25	TBL1XR1-AS1	TBL1XR1 antisense RNA 1	2705	0.37
chr12_3277713_3277864	0.25	TSPAN9-IT1	TSPAN9 intronic transcript 1 (non-protein coding)	18825	0.21
chr6_1770904_1771055	0.24	FOXC1	forkhead box C1	160298	0.04
chr2_101557586_101557737	0.24	NPAS2	neuronal PAS domain protein 2	16037	0.19
chr6_112134687_112134881	0.24	FYN	FYN oncogene related to SRC, FGR, YES	6497	0.3
chr8_81869402_81869553	0.24	ZNF704	zinc finger protein 704	82461	0.1
chr13_97951383_97951534	0.23	MBNL2	muscleblind-like splicing regulator 2	23000	0.24
chr18_8742851_8743002	0.23	ENSG00000252319	.	22796	0.16
chr3_3149713_3149864	0.23	IL5RA	interleukin 5 receptor, alpha	1876	0.29
chr14_99657637_99657788	0.23	AL162151.4		32959	0.19
chr2_43744542_43744693	0.23	THADA	thyroid adenoma associated	53037	0.14
chr7_121081319_121081497	0.22	FAM3C	family with sequence similarity 3, member C	44990	0.18
chr12_123964543_123964694	0.22	RILPL1	Rab interacting lysosomal protein-like 1	4903	0.17
chr2_217416771_217416922	0.22	RPL37A	ribosomal protein L37a	52983	0.1
chr4_124706511_124706662	0.22	SPRY1	sprouty homolog 1, antagonist of FGF signaling (Drosophila)	385463	0.01
chr21_47033891_47034042	0.22	PCBP3	poly(rC) binding protein 3	29642	0.19
chr4_148560196_148560347	0.22	TMEM184C	transmembrane protein 184C	21734	0.17
chr5_95990832_95991103	0.21	CAST	calpastatin	6810	0.2
chr7_157618570_157618721	0.21	AC011899.9		28576	0.2
chr1_223205415_223205566	0.20	TLR5	toll-like receptor 5	102608	0.07
chr1_229422686_229422837	0.20	RAB4A	RAB4A, member RAS oncogene family	15882	0.13
chr8_25118011_25118162	0.20	DOCK5	dedicator of cytokinesis 5	38372	0.2
chr20_61462880_61463031	0.20	COL9A3	collagen, type IX, alpha 3	13792	0.11
chr7_105519340_105519491	0.20	ATXN7L1	ataxin 7-like 1	2365	0.42
chr2_218559324_218559720	0.20	DIRC3	disrupted in renal carcinoma 3	61756	0.14
chr3_182532822_182533066	0.20	ATP11B	ATPase, class VI, type 11B	21653	0.2
chr12_69869485_69869636	0.20	FRS2	fibroblast growth factor receptor substrate 2	5346	0.25
chr12_110747721_110747872	0.20	ATP2A2	ATPase, Ca++ transporting, cardiac muscle, slow twitch 2	17942	0.19
chr14_75354609_75355002	0.19	DLST	dihydrolipoamide S-succinyltransferase (E2 component of 2-oxo-glutarate complex)	6146	0.15
chr2_44805912_44806231	0.19	ENSG00000252896	.	203198	0.02
chr1_209906969_209907244	0.19	RP1-28O10.1		9636	0.14
chr7_90092750_90092901	0.19	CDK14	cyclin-dependent kinase 14	2913	0.32
chr6_43476699_43476850	0.19	POLR1C	polymerase (RNA) I polypeptide C, 30kDa	666	0.45
chr2_173354471_173354622	0.19	ITGA6	integrin, alpha 6	1856	0.31
chr7_157270754_157271005	0.19	AC006372.6		35109	0.17
chr11_3930269_3930460	0.18	STIM1	stromal interaction molecule 1	5671	0.16
chr15_60678126_60678277	0.18	ANXA2	annexin A2	5125	0.3
chr20_37591585_37591911	0.18	DHX35	DEAH (Asp-Glu-Ala-His) box polypeptide 35	761	0.49
chr9_34884772_34884923	0.18	FAM205CP	family with sequence similarity 205, member C, pseudogene	10872	0.18
chr8_10646057_10646208	0.18	ENSG00000252565	.	4567	0.2
chr18_51656918_51657069	0.18	ENSG00000221058	.	43967	0.17
chr2_23603174_23603325	0.18	KLHL29	kelch-like family member 29	4839	0.35
chr12_7033713_7034270	0.18	ATN1	atrophin 1	365	0.64
chr19_47440458_47440691	0.18	ENSG00000252071	.	10972	0.17
chr14_65273841_65273992	0.18	SPTB	spectrin, beta, erythrocytic	15896	0.19
chr11_63713223_63713374	0.18	NAA40	N(alpha)-acetyltransferase 40, NatD catalytic subunit	6578	0.12
chr13_27497937_27498088	0.18	GPR12	G protein-coupled receptor 12	163090	0.03
chr7_30856829_30856980	0.18	AC004691.5		13878	0.19
chr5_133912504_133912664	0.18	SAR1B	SAR1 homolog B (S. cerevisiae)	36192	0.12
chr20_4850289_4850440	0.18	ENSG00000252096	.	734	0.64
chr21_36359457_36360216	0.18	RUNX1	runt-related transcription factor 1	61626	0.16
chr4_114598575_114598944	0.18	CAMK2D	calcium/calmodulin-dependent protein kinase II delta	83465	0.11
chr5_112353844_112353995	0.18	DCP2	decapping mRNA 2	41440	0.16
chr11_36376060_36376211	0.18	PRR5L	proline rich 5 like	4717	0.24
chr8_123982310_123982603	0.17	RP11-557C18.3		32344	0.15
chr11_117100803_117101184	0.17	PCSK7	proprotein convertase subtilisin/kexin type 7	37	0.96
chr17_19555607_19555758	0.17	Y_RNA	Y RNA	2434	0.18
chr5_71078342_71078493	0.17	CARTPT	CART prepropeptide	63427	0.14
chr22_36232750_36232901	0.17	RBFOX2	RNA binding protein, fox-1 homolog (C. elegans) 2	3440	0.35
chr2_150441836_150441994	0.17	AC144449.1		1795	0.33
chr11_108430535_108430686	0.17	EXPH5	exophilin 5	7678	0.24
chr9_14246172_14246323	0.17	NFIB	nuclear factor I/B	61765	0.14
chr9_117657536_117657935	0.17	TNFSF8	tumor necrosis factor (ligand) superfamily, member 8	34962	0.2
chr4_26176730_26176881	0.17	RBPJ	recombination signal binding protein for immunoglobulin kappa J region	11728	0.31
chr9_117460159_117460310	0.17	ENSG00000272241	.	81407	0.07
chr1_86072326_86072477	0.17	ENSG00000199934	.	14438	0.19
chr5_136908229_136908380	0.17	ENSG00000221612	.	39161	0.17
chr2_56185291_56185442	0.17	ENSG00000202344	.	6217	0.18
chr19_34964955_34965106	0.17	WTIP	Wilms tumor 1 interacting protein	6844	0.15
chr17_61787179_61787330	0.17	STRADA	STE20-related kinase adaptor alpha	906	0.52
chr1_46640060_46640211	0.17	TSPAN1	tetraspanin 1	624	0.55
chr16_46673453_46673604	0.17	SHCBP1	SHC SH2-domain binding protein 1	17990	0.16
chrX_153669492_153669643	0.16	FAM50A	family with sequence similarity 50, member A	2906	0.1
chr2_235127665_235127816	0.16	SPP2	secreted phosphoprotein 2, 24kDa	168309	0.03
chr12_65392193_65392344	0.16	ENSG00000221564	.	59465	0.12
chr10_93998131_93998282	0.16	CPEB3	cytoplasmic polyadenylation element binding protein 3	4797	0.2
chr12_51415503_51415654	0.16	SLC11A2	solute carrier family 11 (proton-coupled divalent metal ion transporter), member 2	3048	0.17
chr2_18806956_18807107	0.16	NT5C1B	5'-nucleotidase, cytosolic IB	36193	0.15
chr2_135147327_135147595	0.16	MGAT5	mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase	135631	0.05
chr14_74221100_74221300	0.16	ELMSAN1	ELM2 and Myb/SANT-like domain containing 1	519	0.67
chr2_99342877_99343146	0.16	MGAT4A	mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme A	148	0.97
chr22_40712740_40712891	0.16	ADSL	adenylosuccinate lyase	29692	0.16
chr1_183582141_183582292	0.16	NCF2	neutrophil cytosolic factor 2	22205	0.15
chr3_111793390_111793541	0.16	C3orf52	chromosome 3 open reading frame 52	11717	0.16
chr2_30633333_30633514	0.16	ENSG00000221377	.	21891	0.22
chr5_1599711_1599862	0.16	SDHAP3	succinate dehydrogenase complex, subunit A, flavoprotein pseudogene 3	6382	0.23
chr3_112732462_112732613	0.16	C3orf17	chromosome 3 open reading frame 17	5470	0.15
chr2_173316490_173316641	0.16	AC078883.3		14175	0.17
chr4_77555198_77555349	0.16	AC107072.2		3503	0.26
chr2_62887343_62887530	0.16	AC092155.4		2327	0.33
chr1_77977507_77977658	0.16	AK5	adenylate kinase 5	20210	0.22
chr1_35790473_35790624	0.16	ENSG00000201542	.	14673	0.15
chr14_102307789_102307940	0.16	CTD-2017C7.1		1996	0.29
chr9_117568578_117568898	0.15	TNFSF15	tumor necrosis factor (ligand) superfamily, member 15	332	0.91
chr11_12065341_12065492	0.15	DKK3	dickkopf WNT signaling pathway inhibitor 3	34100	0.19
chr4_110482457_110482611	0.15	CCDC109B	coiled-coil domain containing 109B	388	0.89
chr9_110818840_110818991	0.15	ENSG00000222459	.	137656	0.05
chr2_45795136_45795287	0.15	SRBD1	S1 RNA binding domain 1	57	0.97
chrX_45482348_45482499	0.15	ENSG00000207870	.	123271	0.06
chr8_82099187_82099532	0.15	PAG1	phosphoprotein associated with glycosphingolipid microdomains 1	75056	0.1
chr19_35609327_35609478	0.15	FXYD3	FXYD domain containing ion transport regulator 3	32	0.95
chr12_12476361_12476512	0.15	MANSC1	MANSC domain containing 1	15172	0.16
chr18_74817203_74817354	0.15	MBP	myelin basic protein	61	0.99
chr3_197043921_197044177	0.15	DLG1	discs, large homolog 1 (Drosophila)	17878	0.15
chr11_65550505_65550656	0.15	AP5B1	adaptor-related protein complex 5, beta 1 subunit	2307	0.15
chr11_47237582_47237751	0.15	DDB2	damage-specific DNA binding protein 2, 48kDa	1173	0.3
chr17_39498922_39499073	0.15	KRT33A	keratin 33A	8067	0.09
chr1_161151441_161151597	0.15	B4GALT3	UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 3	4232	0.08
chr4_74618931_74619082	0.15	IL8	interleukin 8	12748	0.22
chr19_47412819_47413067	0.15	ARHGAP35	Rho GTPase activating protein 35	8990	0.18
chr3_37905725_37905876	0.15	CTDSPL	CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like	2135	0.29
chr5_130172490_130172778	0.15	HINT1	histidine triad nucleotide binding protein 1	325686	0.01
chr6_161452505_161452672	0.15	MAP3K4	mitogen-activated protein kinase kinase kinase 4	9362	0.25
chr7_46526418_46526569	0.15	AC011294.3	Uncharacterized protein	210227	0.03
chr4_38466221_38466427	0.15	RP11-617D20.1		159872	0.04
chr6_111914585_111914879	0.15	C6orf3		6346	0.18
chr1_120530540_120530765	0.15	NOTCH2	notch 2	66187	0.11
chr14_94869653_94869804	0.15	SERPINA1	serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1	12698	0.17
chr2_23603644_23603903	0.15	KLHL29	kelch-like family member 29	4315	0.36
chr8_97295512_97295663	0.15	PTDSS1	phosphatidylserine synthase 1	11833	0.16
chr21_42800083_42800234	0.15	MX1	myxovirus (influenza virus) resistance 1, interferon-inducible protein p78 (mouse)	1250	0.46
chr1_77309927_77310078	0.14	ST6GALNAC5	ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 5	23124	0.24
chr13_99037322_99037473	0.14	FARP1	FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived)	7322	0.22
chr14_30662848_30662999	0.14	PRKD1	protein kinase D1	1819	0.52
chr1_11709457_11709768	0.14	FBXO44	F-box protein 44	4820	0.15
chr2_216035940_216036091	0.14	ABCA12	ATP-binding cassette, sub-family A (ABC1), member 12	32864	0.21
chr8_2077178_2077450	0.14	MYOM2	myomesin 2	84130	0.11
chr6_112544857_112545008	0.14	RP11-506B6.6		12362	0.18
chr13_43556037_43556188	0.14	EPSTI1	epithelial stromal interaction 1 (breast)	9255	0.27
chr17_14224308_14224742	0.14	HS3ST3B1	heparan sulfate (glucosamine) 3-O-sulfotransferase 3B1	20125	0.25
chr15_99408895_99409301	0.14	IGF1R	insulin-like growth factor 1 receptor	24472	0.19
chr1_172609208_172609513	0.14	FASLG	Fas ligand (TNF superfamily, member 6)	18794	0.21
chr3_30790892_30791043	0.14	RP11-1024P17.1		51814	0.17
chr5_36418067_36418218	0.14	ENSG00000222178	.	67303	0.12
chr2_42595543_42595694	0.14	COX7A2L	cytochrome c oxidase subunit VIIa polypeptide 2 like	532	0.83
chr4_88024806_88024957	0.14	AFF1	AF4/FMR2 family, member 1	54077	0.15
chr2_191511680_191511970	0.14	NAB1	NGFI-A binding protein 1 (EGR1 binding protein 1)	353	0.9
chr19_55598589_55599242	0.14	EPS8L1	EPS8-like 1	7155	0.1
chr9_21563971_21564122	0.14	MIR31HG	MIR31 host gene (non-protein coding)	4378	0.22
chr18_56364682_56364882	0.14	RP11-126O1.4		19936	0.14
chr7_77543067_77543218	0.14	ENSG00000222432	.	17945	0.23
chr4_89447573_89447724	0.14	PYURF	PIGY upstream reading frame	2684	0.19
chr7_48130946_48131431	0.14	UPP1	uridine phosphorylase 1	2215	0.35
chrY_24588459_24588610	0.14	RBMY1J	RNA binding motif protein, Y-linked, family 1, member J	38917	0.18
chr17_40474977_40475333	0.14	STAT5A	signal transducer and activator of transcription 5A	16967	0.12
chr1_99368541_99368692	0.14	RP5-896L10.1		101216	0.08
chrY_24290097_24290248	0.14	TTTY6B	testis-specific transcript, Y-linked 6B (non-protein coding)	941	0.63
chr3_118943777_118943976	0.14	B4GALT4-AS1	B4GALT4 antisense RNA 1	1457	0.35
chr5_35851470_35851621	0.14	IL7R	interleukin 7 receptor	1252	0.48
chr13_51191815_51191966	0.14	DLEU7-AS1	DLEU7 antisense RNA 1	190102	0.03
chr10_33401450_33401716	0.14	ENSG00000263576	.	14019	0.23
chr8_61444637_61444969	0.14	RAB2A	RAB2A, member RAS oncogene family	15063	0.21
chr10_79263751_79264179	0.14	ENSG00000199592	.	82842	0.09
chr3_71089732_71089883	0.14	FOXP1	forkhead box P1	24270	0.27
chr3_114342591_114342742	0.14	ZBTB20	zinc finger and BTB domain containing 20	387	0.92
chr10_121430393_121430544	0.13	BAG3	BCL2-associated athanogene 3	14346	0.22
chr3_197066805_197066956	0.13	ENSG00000238491	.	458	0.83
chr4_95389192_95389343	0.13	PDLIM5	PDZ and LIM domain 5	12871	0.3
chr9_86916715_86916866	0.13	RP11-380F14.2		23656	0.22
chr17_33586904_33587190	0.13	SLFN5	schlafen family member 5	16939	0.14
chr14_21921429_21921580	0.13	CHD8	chromodomain helicase DNA binding protein 8	2735	0.17
chr1_107816447_107816598	0.13	NTNG1	netrin G1	125306	0.06
chr15_64452312_64452605	0.13	PPIB	peptidylprolyl isomerase B (cyclophilin B)	2946	0.21
chr11_5641771_5641922	0.13	TRIM34	tripartite motif containing 34	852	0.42
chr21_38835524_38835675	0.13	DYRK1A	dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A	25488	0.2
chr8_100335314_100335465	0.13	VPS13B	vacuolar protein sorting 13 homolog B (yeast)	197738	0.02
chr16_29091824_29092152	0.13	RRN3P2	RNA polymerase I transcription factor homolog (S. cerevisiae) pseudogene 2	5645	0.14
chr15_51487830_51487981	0.13	CYP19A1	cytochrome P450, family 19, subfamily A, polypeptide 1	19516	0.19
chr6_108033494_108033645	0.13	SCML4	sex comb on midleg-like 4 (Drosophila)	20030	0.26
chr11_57791866_57792017	0.13	OR9Q1	olfactory receptor, family 9, subfamily Q, member 1	588	0.69
chr19_46725804_46725955	0.13	IGFL1	IGF-like family member 1	7130	0.16
chr1_116809625_116809776	0.13	ENSG00000221040	.	11528	0.25
chr10_100096333_100096484	0.13	ENSG00000221419	.	58656	0.11
chr1_165615005_165615300	0.13	MGST3	microsomal glutathione S-transferase 3	13675	0.17
chr1_175138890_175139041	0.13	KIAA0040	KIAA0040	22925	0.22
chr14_25472864_25473158	0.13	STXBP6	syntaxin binding protein 6 (amisyn)	6835	0.32
chr5_37769320_37769471	0.13	ENSG00000238335	.	32772	0.19
chr4_119771770_119771921	0.13	SEC24D	SEC24 family member D	12020	0.25
chr20_49526597_49526748	0.13	ADNP	activity-dependent neuroprotector homeobox	344	0.84
chr17_55131688_55131839	0.13	AKAP1	A kinase (PRKA) anchor protein 1	30690	0.13
chr10_29936930_29937596	0.13	SVIL	supervillin	13362	0.21
chr2_150984198_150984349	0.13	RND3	Rho family GTPase 3	357623	0.01
chr10_82282364_82282515	0.13	RP11-137H2.4		13259	0.2
chr1_174121426_174121577	0.13	RABGAP1L	RAB GTPase activating protein 1-like	7047	0.24
chr2_170929420_170929661	0.13	ENSG00000252807	.	47068	0.16
chr6_7647980_7648131	0.13	SNRNP48	small nuclear ribonucleoprotein 48kDa (U11/U12)	57623	0.13
chr1_152857238_152857389	0.13	SMCP	sperm mitochondria-associated cysteine-rich protein	6520	0.12
chr10_13816214_13816365	0.13	RP11-353M9.1		44906	0.11
chr7_150209562_150209829	0.13	GIMAP7	GTPase, IMAP family member 7	2223	0.31
chr13_74573133_74573284	0.13	KLF12	Kruppel-like factor 12	4022	0.38
chr15_42349993_42350144	0.13	PLA2G4E	phospholipase A2, group IVE	6680	0.17
chr9_114808212_114808363	0.13	RP11-4O1.2		8277	0.21

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of PRDM1

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Total log-likelihood	Term	Description
0.1	GO:0031946	regulation of glucocorticoid biosynthetic process(GO:0031946)
0.1	GO:0060049	regulation of protein glycosylation(GO:0060049)
0.1	GO:0031340	positive regulation of vesicle fusion(GO:0031340)
0.1	GO:0001911	negative regulation of leukocyte mediated cytotoxicity(GO:0001911)
0.1	GO:0019471	peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401) 4-hydroxyproline metabolic process(GO:0019471) peptidyl-proline hydroxylation(GO:0019511)
0.1	GO:0001845	phagolysosome assembly(GO:0001845) phagosome maturation(GO:0090382)
0.1	GO:0001743	optic placode formation(GO:0001743)
0.1	GO:0032467	positive regulation of cytokinesis(GO:0032467)
0.1	GO:0033314	mitotic DNA replication checkpoint(GO:0033314)
0.1	GO:0007221	positive regulation of transcription of Notch receptor target(GO:0007221)
0.0	GO:0070208	protein heterotrimerization(GO:0070208)
0.1	GO:0046520	sphingoid biosynthetic process(GO:0046520)
0.1	GO:0015917	aminophospholipid transport(GO:0015917)
0.1	GO:0097061	dendritic spine morphogenesis(GO:0060997) regulation of dendritic spine morphogenesis(GO:0061001) dendritic spine organization(GO:0097061)
0.1	GO:0009404	toxin metabolic process(GO:0009404)
0.1	GO:0006491	N-glycan processing(GO:0006491)
0.2	GO:0031581	hemidesmosome assembly(GO:0031581)
0.0	GO:0015015	heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.0	GO:0070669	response to interleukin-2(GO:0070669)
0.0	GO:0006290	pyrimidine dimer repair(GO:0006290)
0.1	GO:0061088	regulation of sequestering of zinc ion(GO:0061088)
0.0	GO:0033023	mast cell homeostasis(GO:0033023) mast cell apoptotic process(GO:0033024) regulation of mast cell apoptotic process(GO:0033025)
0.1	GO:0043589	skin morphogenesis(GO:0043589)
0.1	GO:0033631	cell-cell adhesion mediated by integrin(GO:0033631)
0.0	GO:0060900	embryonic camera-type eye formation(GO:0060900)
0.0	GO:0097501	detoxification of inorganic compound(GO:0061687) stress response to metal ion(GO:0097501)
0.0	GO:0045048	protein insertion into ER membrane(GO:0045048) tail-anchored membrane protein insertion into ER membrane(GO:0071816)
0.1	GO:0070120	ciliary neurotrophic factor-mediated signaling pathway(GO:0070120)
0.0	GO:0060737	prostate gland morphogenetic growth(GO:0060737)
0.2	GO:1901222	activation of NF-kappaB-inducing kinase activity(GO:0007250) NIK/NF-kappaB signaling(GO:0038061) regulation of NIK/NF-kappaB signaling(GO:1901222) positive regulation of NIK/NF-kappaB signaling(GO:1901224)
0.1	GO:0060501	positive regulation of epithelial cell proliferation involved in lung morphogenesis(GO:0060501) regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000794)
0.1	GO:0045657	positive regulation of monocyte differentiation(GO:0045657)
0.0	GO:0048388	endosomal lumen acidification(GO:0048388)
0.1	GO:0034501	protein localization to kinetochore(GO:0034501)
0.1	GO:0042023	regulation of DNA endoreduplication(GO:0032875) negative regulation of DNA endoreduplication(GO:0032876) DNA endoreduplication(GO:0042023)
0.0	GO:0060502	epithelial cell proliferation involved in lung morphogenesis(GO:0060502)
0.0	GO:0034392	negative regulation of smooth muscle cell apoptotic process(GO:0034392)
0.0	GO:0070779	D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
0.1	GO:0014037	Schwann cell differentiation(GO:0014037)
0.0	GO:0003032	detection of oxygen(GO:0003032)
0.0	GO:0006167	AMP biosynthetic process(GO:0006167)
0.0	GO:0032525	somite rostral/caudal axis specification(GO:0032525)
0.0	GO:0032431	activation of phospholipase A2 activity(GO:0032431)
0.0	GO:0022030	cerebral cortex radial glia guided migration(GO:0021801) telencephalon glial cell migration(GO:0022030)
0.0	GO:0000212	meiotic spindle organization(GO:0000212)
0.0	GO:0043457	regulation of cellular respiration(GO:0043457)
0.0	GO:0003323	type B pancreatic cell development(GO:0003323)
0.0	GO:0051138	NK T cell differentiation(GO:0001865) regulation of NK T cell differentiation(GO:0051136) positive regulation of NK T cell differentiation(GO:0051138)
0.0	GO:0021869	forebrain ventricular zone progenitor cell division(GO:0021869)
0.0	GO:0070296	sarcoplasmic reticulum calcium ion transport(GO:0070296)
0.0	GO:0032486	Rap protein signal transduction(GO:0032486)
0.0	GO:0032347	regulation of ketone biosynthetic process(GO:0010566) regulation of aldosterone metabolic process(GO:0032344) regulation of aldosterone biosynthetic process(GO:0032347)
0.0	GO:0060340	positive regulation of type I interferon-mediated signaling pathway(GO:0060340)
0.0	GO:0033603	positive regulation of dopamine secretion(GO:0033603)
0.0	GO:0032823	regulation of natural killer cell differentiation(GO:0032823) positive regulation of natural killer cell differentiation(GO:0032825)
0.0	GO:0002538	arachidonic acid metabolite production involved in inflammatory response(GO:0002538) leukotriene production involved in inflammatory response(GO:0002540)

Gene overrepresentation in cellular component category:

Total log-likelihood	Term	Description
0.1	GO:0043218	compact myelin(GO:0043218)
0.1	GO:0031229	integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229) nuclear membrane part(GO:0044453)
0.1	GO:0002178	palmitoyltransferase complex(GO:0002178) serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211)
0.1	GO:0071437	invadopodium(GO:0071437)
0.1	GO:0005736	DNA-directed RNA polymerase I complex(GO:0005736)
0.1	GO:0033268	node of Ranvier(GO:0033268)
0.1	GO:0005954	calcium- and calmodulin-dependent protein kinase complex(GO:0005954)
0.0	GO:0071818	BAT3 complex(GO:0071818) ER membrane insertion complex(GO:0072379)
0.0	GO:0031235	intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.1	GO:0005606	laminin-1 complex(GO:0005606)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.2	GO:0008454	alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.0	0.1	GO:0019911	structural constituent of myelin sheath(GO:0019911)
0.0	0.1	GO:0004758	serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
0.0	0.1	GO:0005010	insulin-like growth factor-activated receptor activity(GO:0005010)
0.0	0.1	GO:0005006	epidermal growth factor-activated receptor activity(GO:0005006)
0.0	0.2	GO:0005123	death receptor binding(GO:0005123)
0.0	0.1	GO:0008432	JUN kinase binding(GO:0008432)
0.0	0.1	GO:0005173	stem cell factor receptor binding(GO:0005173)
0.0	0.1	GO:0016842	amidine-lyase activity(GO:0016842)
0.0	0.1	GO:0042043	neurexin family protein binding(GO:0042043)
0.0	0.1	GO:0004656	procollagen-proline 4-dioxygenase activity(GO:0004656) peptidyl-proline 4-dioxygenase activity(GO:0031545)
0.0	0.1	GO:0004937	alpha1-adrenergic receptor activity(GO:0004937)
0.0	0.1	GO:0004897	ciliary neurotrophic factor receptor activity(GO:0004897)
0.0	0.2	GO:0004697	protein kinase C activity(GO:0004697)
0.0	0.1	GO:0005384	manganese ion transmembrane transporter activity(GO:0005384)
0.0	0.1	GO:0003945	N-acetyllactosamine synthase activity(GO:0003945)
0.0	0.0	GO:0004594	pantothenate kinase activity(GO:0004594)
0.0	0.0	GO:0016149	translation release factor activity, codon specific(GO:0016149)
0.0	0.1	GO:0035381	extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
0.0	0.0	GO:0005148	prolactin receptor binding(GO:0005148)
0.0	0.1	GO:0019211	phosphatase activator activity(GO:0019211)
0.0	0.0	GO:0045236	CXCR chemokine receptor binding(GO:0045236)
0.0	0.1	GO:0017081	chloride channel regulator activity(GO:0017081)
0.0	0.0	GO:0004792	thiosulfate sulfurtransferase activity(GO:0004792)
0.0	0.1	GO:0042805	actinin binding(GO:0042805)
0.0	0.0	GO:0016748	succinyltransferase activity(GO:0016748)
0.0	0.1	GO:0004859	phospholipase inhibitor activity(GO:0004859)
0.0	0.0	GO:0010314	phosphatidylinositol-5-phosphate binding(GO:0010314)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.0	0.2	PID INTEGRIN4 PATHWAY	Alpha6 beta4 integrin-ligand interactions
0.0	0.2	PID SYNDECAN 3 PATHWAY	Syndecan-3-mediated signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Total log-likelihood	Term	Description
0.2	REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN	Genes involved in Platelet Adhesion to exposed collagen
0.2	REACTOME N GLYCAN ANTENNAE ELONGATION	Genes involved in N-Glycan antennae elongation
0.2	REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION	Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.2	REACTOME G0 AND EARLY G1	Genes involved in G0 and Early G1
0.0	REACTOME TRAF6 MEDIATED IRF7 ACTIVATION	Genes involved in TRAF6 mediated IRF7 activation