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ENCODE: H3K4me1 ChIP-Seq of primary human cells

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CREMA is a free online tool that recognizes most important transcription factors that change the chromatin state across different samples.

Results for PRDM4

Z-value: 0.54

Motif logo

Transcription factors associated with PRDM4

Gene Symbol	Gene ID	Gene Info
PRDM4 Ensembl NCBI GeneCards UniProt	ENSG00000110851.7	PRDM4

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE	Gene	Distance	Association probability	Pearson corr. coef.	P-value	Plot
PRDM4	chr12_108153016_108153187	1604	0.340966	0.77	1.5e-02	Click!
PRDM4	chr12_108155478_108155661	632	0.688013	0.72	3.0e-02	Click!
PRDM4	chr12_108142593_108142899	2806	0.228115	0.60	8.6e-02	Click!
PRDM4	chr12_108143057_108143208	2420	0.249573	0.59	9.2e-02	Click!
PRDM4	chr12_108155237_108155454	408	0.824255	0.51	1.6e-01	Click!

Activity of the PRDM4 motif across conditions

Conditions sorted by the z-value of the PRDM4 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE)	Target Score	Top associated gene	Gene Info	Distance of CRE to TSS	CRE/Gene association probability
chr1_111742539_111742690	0.33	DENND2D	DENN/MADD domain containing 2D	697	0.41
chr13_31350829_31350980	0.29	ALOX5AP	arachidonate 5-lipoxygenase-activating protein	41259	0.19
chr3_149291004_149291431	0.28	WWTR1	WW domain containing transcription regulator 1	2822	0.29
chr1_222439575_222440052	0.28	ENSG00000222399	.	237264	0.02
chr12_79960162_79960313	0.28	PAWR	PRKC, apoptosis, WT1, regulator	30077	0.18
chr5_1315108_1315672	0.26	ENSG00000263670	.	5898	0.18
chr22_38864249_38864461	0.25	KDELR3	KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 3	272	0.87
chr16_54002972_54003123	0.25	RP11-357N13.3		12777	0.19
chr9_130099707_130099858	0.23	RP11-356B19.11		29267	0.15
chr1_85163731_85163882	0.23	SSX2IP	synovial sarcoma, X breakpoint 2 interacting protein	7320	0.25
chr11_66792089_66792328	0.22	SYT12	synaptotagmin XII	1392	0.35
chr2_43268497_43268648	0.22	ENSG00000207087	.	50060	0.18
chrX_53112022_53112186	0.22	TSPYL2	TSPY-like 2	541	0.77
chr11_94259306_94259474	0.22	FUT4	fucosyltransferase 4 (alpha (1,3) fucosyltransferase, myeloid-specific)	17627	0.14
chr17_80259593_80259778	0.22	CD7	CD7 molecule	15743	0.1
chr9_37906834_37906985	0.21	SLC25A51	solute carrier family 25, member 51	2779	0.3
chr2_201831570_201831721	0.21	ORC2	origin recognition complex, subunit 2	3242	0.16
chr2_25016966_25017192	0.21	CENPO	centromere protein O	746	0.43
chr11_67188943_67189234	0.21	PPP1CA	protein phosphatase 1, catalytic subunit, alpha isozyme	434	0.59
chr5_137367346_137367953	0.21	RP11-325L7.1		814	0.42
chr15_90394457_90394608	0.21	ENSG00000264966	.	579	0.63
chr2_26235492_26235765	0.20	AC013449.1	Uncharacterized protein	15853	0.16
chr7_19157255_19157514	0.20	TWIST1	twist family bHLH transcription factor 1	89	0.96
chr2_69387532_69387683	0.20	ENSG00000251850	.	21528	0.17
chr13_25575618_25575781	0.20	LSP1	Lymphocyte-specific protein 1; Uncharacterized protein	15842	0.2
chr2_56968506_56968657	0.20	ENSG00000238690	.	274718	0.02
chr14_93568704_93568855	0.19	ITPK1	inositol-tetrakisphosphate 1-kinase	12838	0.19
chr22_45074770_45074921	0.19	PRR5	proline rich 5 (renal)	1880	0.36
chrX_48931245_48931459	0.19	PRAF2	PRA1 domain family, member 2	296	0.76
chr1_17338947_17339284	0.19	ATP13A2	ATPase type 13A2	692	0.64
chr14_54640379_54640530	0.19	BMP4	bone morphogenetic protein 4	214975	0.02
chr5_168778916_168779067	0.19	SLIT3	slit homolog 3 (Drosophila)	50858	0.16
chr11_34622592_34622743	0.19	EHF	ets homologous factor	19991	0.24
chr14_62210337_62210488	0.19	SNAPC1	small nuclear RNA activating complex, polypeptide 1, 43kDa	18663	0.23
chr15_52068834_52068985	0.19	CTD-2308G16.1		24227	0.12
chr17_44895119_44895270	0.19	WNT3	wingless-type MMTV integration site family, member 3	932	0.59
chr14_100086310_100086646	0.18	CCDC85C	coiled-coil domain containing 85C	16115	0.16
chr17_48225528_48225728	0.18	PPP1R9B	protein phosphatase 1, regulatory subunit 9B	2249	0.16
chr9_130912945_130913096	0.18	LCN2	lipocalin 2	1223	0.26
chr2_8724165_8724340	0.18	AC011747.7		91644	0.09
chr3_189815522_189815673	0.18	ENSG00000265045	.	16126	0.16
chr5_151064438_151064589	0.17	SPARC	secreted protein, acidic, cysteine-rich (osteonectin)	278	0.88
chr3_61549743_61550025	0.17	PTPRG	protein tyrosine phosphatase, receptor type, G	2299	0.46
chr12_105628226_105628978	0.17	APPL2	adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 2	1259	0.53
chr10_79470908_79471170	0.17	ENSG00000199664	.	65774	0.1
chr6_42898064_42898621	0.17	CNPY3	canopy FGF signaling regulator 3	1360	0.27
chr17_41855515_41855877	0.17	DUSP3	dual specificity phosphatase 3	609	0.57
chr12_50454604_50454755	0.17	ASIC1	acid-sensing (proton-gated) ion channel 1	1009	0.41
chr21_18375200_18375601	0.17	ENSG00000239023	.	284083	0.01
chr12_4380731_4380910	0.17	CCND2	cyclin D2	2118	0.26
chr6_158691741_158691892	0.17	TULP4	tubby like protein 4	41876	0.16
chr10_72424836_72424987	0.17	ADAMTS14	ADAM metallopeptidase with thrombospondin type 1 motif, 14	7648	0.25
chr2_122290670_122290831	0.17	ENSG00000264229	.	2293	0.27
chr10_71097859_71098010	0.17	HK1	hexokinase 1	19334	0.16
chr19_4455695_4455846	0.16	UBXN6	UBX domain protein 6	335	0.7
chr15_74286445_74286665	0.16	STOML1	stomatin (EPB72)-like 1	408	0.5
chr2_28395125_28395276	0.16	AC093690.1		138126	0.04
chr18_8425692_8425843	0.16	RP11-789C17.5		18816	0.15
chr6_90321441_90321592	0.16	ANKRD6	ankyrin repeat domain 6	12170	0.18
chr8_38385959_38386435	0.16	C8orf86	chromosome 8 open reading frame 86	17	0.98
chr5_75820010_75820161	0.16	IQGAP2	IQ motif containing GTPase activating protein 2	23149	0.22
chr1_16179252_16179441	0.16	RP11-169K16.9		4704	0.16
chr11_14395280_14395431	0.16	RRAS2	related RAS viral (r-ras) oncogene homolog 2	9303	0.27
chr6_156876303_156876454	0.15	ENSG00000212295	.	176494	0.03
chr1_203598875_203599076	0.15	ATP2B4	ATPase, Ca++ transporting, plasma membrane 4	3047	0.32
chr20_43201718_43201928	0.15	PKIG	protein kinase (cAMP-dependent, catalytic) inhibitor gamma	9367	0.16
chr2_234259348_234259499	0.15	RP11-400N9.1		2639	0.2
chr16_85234171_85234322	0.15	CTC-786C10.1		29364	0.2
chr19_4456946_4457150	0.15	UBXN6	UBX domain protein 6	771	0.38
chr10_75692622_75693009	0.15	C10orf55	chromosome 10 open reading frame 55	10280	0.15
chr9_116330141_116330292	0.15	RGS3	regulator of G-protein signaling 3	2855	0.3
chr3_128775670_128775821	0.14	GP9	glycoprotein IX (platelet)	3865	0.16
chr9_37148680_37148906	0.14	ENSG00000200502	.	11341	0.19
chr9_33106902_33107053	0.14	B4GALT1	UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1	21220	0.14
chr1_44727874_44728025	0.14	ERI3-IT1	ERI3 intronic transcript 1 (non-protein coding)	18004	0.17
chr5_62015700_62015851	0.14	LRRC70	leucine rich repeat containing 70	141073	0.05
chr13_27750626_27750777	0.14	USP12-AS2	USP12 antisense RNA 2 (head to head)	4305	0.17
chr19_44284913_44285064	0.14	KCNN4	potassium intermediate/small conductance calcium-activated channel, subfamily N, member 4	421	0.77
chr19_38773150_38773313	0.14	SPINT2	serine peptidase inhibitor, Kunitz type, 2	6547	0.09
chr5_173887293_173887444	0.14	MSX2	msh homeobox 2	264168	0.02
chr13_47166086_47166307	0.14	LRCH1	leucine-rich repeats and calponin homology (CH) domain containing 1	38801	0.2
chr5_61564461_61564612	0.14	KIF2A	kinesin heavy chain member 2A	37453	0.2
chr1_46598395_46598546	0.14	PIK3R3	phosphoinositide-3-kinase, regulatory subunit 3 (gamma)	4	0.96
chr13_28673916_28674156	0.14	FLT3	fms-related tyrosine kinase 3	671	0.71
chr5_179333448_179333798	0.14	TBC1D9B	TBC1 domain family, member 9B (with GRAM domain)	1233	0.4
chr10_124251115_124251760	0.14	HTRA1	HtrA serine peptidase 1	14770	0.19
chr12_8068842_8069133	0.14	SLC2A3	solute carrier family 2 (facilitated glucose transporter), member 3	19795	0.12
chr14_97250693_97250844	0.14	VRK1	vaccinia related kinase 1	12873	0.29
chr20_48938593_48938744	0.13	ENSG00000244376	.	107352	0.06
chr7_100743308_100743577	0.13	RP11-395B7.7		6114	0.12
chr5_150478539_150478923	0.13	TNIP1	TNFAIP3 interacting protein 1	5593	0.21
chrX_48823976_48824127	0.13	KCND1	potassium voltage-gated channel, Shal-related subfamily, member 1	742	0.47
chr19_35264246_35264397	0.13	ZNF599	zinc finger protein 599	187	0.94
chr2_47261810_47262026	0.13	AC093732.1		5745	0.21
chr19_54783760_54783911	0.13	LILRB2	leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 2	518	0.56
chr7_116347170_116347321	0.13	MET	met proto-oncogene	8106	0.26
chr15_57853447_57853737	0.13	GCOM1	GRINL1A complex locus 1	30514	0.16
chr11_19138835_19138986	0.13	ZDHHC13	zinc finger, DHHC-type containing 13	218	0.95
chr9_80598456_80598705	0.13	GNAQ	guanine nucleotide binding protein (G protein), q polypeptide	46940	0.2
chr2_101508141_101508354	0.13	NPAS2	neuronal PAS domain protein 2	33361	0.18
chr16_57849254_57849515	0.12	CTD-2600O9.1	uncharacterized protein LOC388282	1700	0.28
chr19_46172040_46172401	0.12	GIPR	gastric inhibitory polypeptide receptor	705	0.44
chr17_18219237_18220149	0.12	SMCR8	Smith-Magenis syndrome chromosome region, candidate 8	1069	0.33
chr10_104159667_104159877	0.12	NFKB2	nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)	4309	0.13
chr6_24721187_24721338	0.12	C6orf62	chromosome 6 open reading frame 62	198	0.92
chr17_40823699_40823850	0.12	PLEKHH3	pleckstrin homology domain containing, family H (with MyTH4 domain) member 3	5195	0.09
chr16_77822104_77822255	0.12	VAT1L	vesicle amine transport 1-like	248	0.94
chr1_200864757_200864948	0.12	C1orf106	chromosome 1 open reading frame 106	903	0.57
chr6_6724772_6724926	0.12	LY86-AS1	LY86 antisense RNA 1	101845	0.08
chr7_128750526_128750677	0.12	TSPAN33	tetraspanin 33	34111	0.12
chr10_47751566_47751717	0.12	ANXA8L2	annexin A8-like 2	4605	0.2
chr5_159343961_159344112	0.11	ADRA1B	adrenoceptor alpha 1B	246	0.95
chr3_42162356_42162507	0.11	TRAK1	trafficking protein, kinesin binding 1	28296	0.22
chr16_54114459_54114610	0.11	RP11-357N13.1		26039	0.19
chr7_560873_561024	0.11	PDGFA	platelet-derived growth factor alpha polypeptide	1015	0.55
chr17_62626812_62627023	0.11	SMURF2	SMAD specific E3 ubiquitin protein ligase 2	31113	0.16
chr9_71814865_71815110	0.11	TJP2	tight junction protein 2	4940	0.28
chr1_40357816_40357967	0.11	RP1-118J21.5		5526	0.13
chr6_169295294_169295588	0.11	SMOC2	SPARC related modular calcium binding 2	241677	0.02
chr18_45550143_45550294	0.11	ZBTB7C	zinc finger and BTB domain containing 7C	17276	0.26
chr21_36450286_36450437	0.11	RUNX1	runt-related transcription factor 1	28720	0.26
chr16_84027429_84027580	0.11	NECAB2	N-terminal EF-hand calcium binding protein 2	4353	0.18
chr4_83720202_83720557	0.11	SCD5	stearoyl-CoA desaturase 5	369	0.87
chrX_13109276_13109427	0.11	FAM9C	family with sequence similarity 9, member C	46550	0.17
chr17_71301605_71301911	0.11	CDC42EP4	CDC42 effector protein (Rho GTPase binding) 4	5789	0.21
chr5_80256745_80257142	0.11	CTC-459I6.1		217	0.74
chr9_116347368_116347519	0.11	RGS3	regulator of G-protein signaling 3	3091	0.28
chr15_68290687_68290838	0.11	PIAS1	protein inhibitor of activated STAT, 1	55755	0.15
chr3_50377357_50377700	0.11	RASSF1	Ras association (RalGDS/AF-6) domain family member 1	744	0.31
chr3_10246879_10247034	0.11	ENSG00000222348	.	11940	0.12
chr17_27485404_27485555	0.11	RP11-321A17.4		17978	0.14
chr19_10107104_10107255	0.11	CTD-2553C6.1		506	0.66
chr8_21776073_21776500	0.11	XPO7	exportin 7	894	0.58
chr11_117881983_117882134	0.11	IL10RA	interleukin 10 receptor, alpha	24949	0.15
chr8_41733784_41734000	0.11	ANK1	ankyrin 1, erythrocytic	20388	0.18
chr2_232537885_232538036	0.11	ENSG00000239202	.	26976	0.14
chr10_121276486_121276651	0.10	RGS10	regulator of G-protein signaling 10	10421	0.24
chrX_152735117_152735698	0.10	TREX2	three prime repair exonuclease 2	638	0.39
chr12_7028808_7028959	0.10	ENO2	enolase 2 (gamma, neuronal)	1861	0.12
chr2_65355385_65355675	0.10	RAB1A	RAB1A, member RAS oncogene family	1705	0.38
chr12_66542003_66542154	0.10	LLPH	LLP homolog, long-term synaptic facilitation (Aplysia)	17530	0.14
chr11_129306549_129306700	0.10	BARX2	BARX homeobox 2	555	0.86
chr22_35936708_35937003	0.10	RASD2	RASD family, member 2	60	0.98
chr3_37156478_37156973	0.10	ENSG00000206645	.	22000	0.14
chr7_73242662_73242860	0.10	CLDN4	claudin 4	257	0.9
chr19_43492235_43492386	0.10	PSG11	pregnancy specific beta-1-glycoprotein 11	38290	0.15
chr14_23010998_23011272	0.10	TRAJ15	T cell receptor alpha joining 15	12555	0.1
chr9_136004894_136005071	0.10	RALGDS	ral guanine nucleotide dissociation stimulator	194	0.92
chr19_12750779_12750960	0.10	ENSG00000221343	.	10321	0.08
chr6_36992914_36993078	0.10	FGD2	FYVE, RhoGEF and PH domain containing 2	19573	0.16
chr7_100450992_100451180	0.10	SLC12A9	solute carrier family 12, member 9	178	0.84
chr11_60684078_60684312	0.10	RP11-881M11.1		2671	0.12
chr10_102774505_102774656	0.10	PDZD7	PDZ domain containing 7	4046	0.12
chr11_76504486_76504637	0.10	TSKU	tsukushi, small leucine rich proteoglycan	1765	0.27
chr5_118692106_118692257	0.10	TNFAIP8	tumor necrosis factor, alpha-induced protein 8	451	0.85
chr11_118216506_118216657	0.10	CD3G	CD3g molecule, gamma (CD3-TCR complex)	1510	0.25
chr14_52781122_52781321	0.10	PTGER2	prostaglandin E receptor 2 (subtype EP2), 53kDa	108	0.98
chrX_30927642_30927793	0.10	TAB3	TGF-beta activated kinase 1/MAP3K7 binding protein 3	42398	0.16
chr3_157147647_157147798	0.10	PTX3	pentraxin 3, long	6856	0.28
chrX_109258822_109259107	0.10	TMEM164	transmembrane protein 164	12621	0.23
chr12_97300289_97300518	0.10	NEDD1	neural precursor cell expressed, developmentally down-regulated 1	598	0.84
chr6_44088597_44088748	0.10	TMEM63B	transmembrane protein 63B	5979	0.16
chr19_49929335_49929486	0.10	GFY	golgi-associated, olfactory signaling regulator	2404	0.1
chr17_25957355_25957572	0.10	LGALS9	lectin, galactoside-binding, soluble, 9	639	0.66
chr8_52784150_52784444	0.10	RP11-110G21.2		24637	0.15
chr4_79566506_79566831	0.10	ENSG00000238816	.	5414	0.24
chrX_129313027_129313307	0.10	RAB33A	RAB33A, member RAS oncogene family	7544	0.2
chr13_80916476_80916855	0.10	SPRY2	sprouty homolog 2 (Drosophila)	1579	0.5
chr8_94712276_94712536	0.10	FAM92A1	family with sequence similarity 92, member A1	74	0.73
chr1_175148249_175148400	0.10	KIAA0040	KIAA0040	13566	0.25
chr14_32030047_32030317	0.10	CTD-2213F21.3		358	0.51
chr11_12699502_12699653	0.10	TEAD1	TEA domain family member 1 (SV40 transcriptional enhancer factor)	2527	0.41
chr10_78112529_78112680	0.09	C10orf11	chromosome 10 open reading frame 11	34512	0.19
chr10_105678306_105678464	0.09	OBFC1	oligonucleotide/oligosaccharide-binding fold containing 1	422	0.83
chr14_92939950_92940432	0.09	SLC24A4	solute carrier family 24 (sodium/potassium/calcium exchanger), member 4	34483	0.19
chr3_189812219_189812584	0.09	ENSG00000265045	.	19322	0.16
chr12_105352498_105352769	0.09	SLC41A2	solute carrier family 41 (magnesium transporter), member 2	111	0.96
chr10_88728173_88728414	0.09	ADIRF	adipogenesis regulatory factor	104	0.83
chr5_10479157_10479308	0.09	RP11-1C1.7		251	0.91
chr14_105865307_105865580	0.09	TEX22	testis expressed 22	523	0.68
chr19_43323943_43324094	0.09	PSG10P	pregnancy specific beta-1-glycoprotein 10, pseudogene	35753	0.14
chr3_140959724_140959879	0.09	ACPL2	acid phosphatase-like 2	9083	0.26
chr6_14982614_14982765	0.09	ENSG00000242989	.	130510	0.05
chr6_126067967_126068118	0.09	HEY2	hes-related family bHLH transcription factor with YRPW motif 2	768	0.54
chr1_147071041_147071332	0.09	BCL9	B-cell CLL/lymphoma 9	58004	0.12
chr10_125754388_125754539	0.09	CHST15	carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15	51778	0.14
chr12_104682747_104683040	0.09	TXNRD1	thioredoxin reductase 1	220	0.93
chr15_59469993_59470144	0.09	ENSG00000253030	.	6607	0.12
chr15_66702964_66703177	0.09	MAP2K1	mitogen-activated protein kinase kinase 1	23915	0.1
chr6_167764133_167764284	0.09	TTLL2	tubulin tyrosine ligase-like family, member 2	25634	0.19
chr20_31496364_31496515	0.09	EFCAB8	EF-hand calcium binding domain 8	3020	0.26
chr7_143079009_143079384	0.09	ZYX	zyxin	196	0.88
chr8_6502180_6502331	0.09	CTD-2541M15.1		4073	0.28
chr11_57137430_57137581	0.09	ENSG00000266018	.	10309	0.09
chr17_684423_684868	0.09	GLOD4	glyoxalase domain containing 4	862	0.35
chr22_19826753_19826904	0.09	C22orf29	chromosome 22 open reading frame 29	15511	0.15
chr21_34775255_34775406	0.09	IFNGR2	interferon gamma receptor 2 (interferon gamma transducer 1)	128	0.96
chr12_71167708_71167859	0.09	PTPRR	protein tyrosine phosphatase, receptor type, R	14979	0.28
chr6_4134938_4135201	0.09	RP3-400B16.4		588	0.45
chr5_149969357_149969508	0.09	SYNPO	synaptopodin	11210	0.16

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of PRDM4

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Total log-likelihood	Term	Description
0.1	GO:0010511	regulation of phosphatidylinositol biosynthetic process(GO:0010511)
0.1	GO:0003099	positive regulation of the force of heart contraction by chemical signal(GO:0003099)
0.1	GO:0048669	collateral sprouting in absence of injury(GO:0048669)
0.1	GO:0034204	lipid translocation(GO:0034204) phospholipid translocation(GO:0045332)
0.1	GO:0042637	catagen(GO:0042637)
0.2	GO:0097094	cranial suture morphogenesis(GO:0060363) craniofacial suture morphogenesis(GO:0097094)
0.2	GO:0015693	magnesium ion transport(GO:0015693)
0.2	GO:0035437	protein retention in ER lumen(GO:0006621) maintenance of protein localization in endoplasmic reticulum(GO:0035437)
0.1	GO:0002538	arachidonic acid metabolite production involved in inflammatory response(GO:0002538) leukotriene production involved in inflammatory response(GO:0002540)
0.2	GO:0050858	negative regulation of antigen receptor-mediated signaling pathway(GO:0050858) negative regulation of T cell receptor signaling pathway(GO:0050860)
0.1	GO:0034625	fatty acid elongation, monounsaturated fatty acid(GO:0034625)
0.1	GO:0006032	chitin metabolic process(GO:0006030) chitin catabolic process(GO:0006032)
0.1	GO:0019987	obsolete negative regulation of anti-apoptosis(GO:0019987)
0.1	GO:0060390	regulation of SMAD protein import into nucleus(GO:0060390)
0.1	GO:0031065	positive regulation of histone deacetylation(GO:0031065)
0.1	GO:0033235	positive regulation of protein sumoylation(GO:0033235)
0.0	GO:0046502	uroporphyrinogen III metabolic process(GO:0046502)
0.1	GO:0060437	lung growth(GO:0060437)
0.0	GO:0097709	connective tissue replacement involved in inflammatory response wound healing(GO:0002248) connective tissue replacement(GO:0097709)
0.0	GO:0006167	AMP biosynthetic process(GO:0006167)
0.1	GO:0030854	positive regulation of granulocyte differentiation(GO:0030854)
0.0	GO:0032203	telomere formation via telomerase(GO:0032203)
0.0	GO:0042635	positive regulation of hair cycle(GO:0042635) positive regulation of hair follicle development(GO:0051798)
0.0	GO:0035511	oxidative DNA demethylation(GO:0035511)
0.1	GO:0032957	inositol trisphosphate metabolic process(GO:0032957)
0.0	GO:0021834	chemorepulsion involved in embryonic olfactory bulb interneuron precursor migration(GO:0021834)
0.0	GO:1903521	apoptotic process involved in mammary gland involution(GO:0060057) positive regulation of apoptotic process involved in mammary gland involution(GO:0060058) positive regulation of apoptotic process involved in morphogenesis(GO:1902339) regulation of mammary gland involution(GO:1903519) positive regulation of mammary gland involution(GO:1903521) positive regulation of apoptotic process involved in development(GO:1904747)

Gene overrepresentation in cellular component category:

Total log-likelihood	Term	Description
0.1	GO:0070188	obsolete Stn1-Ten1 complex(GO:0070188)
0.1	GO:0016327	apicolateral plasma membrane(GO:0016327)
0.1	GO:0072357	PTW/PP1 phosphatase complex(GO:0072357)
0.1	GO:0031312	extrinsic component of organelle membrane(GO:0031312)
0.1	GO:0000808	origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.2	GO:0046923	ER retention sequence binding(GO:0046923)
0.0	0.2	GO:0015095	magnesium ion transmembrane transporter activity(GO:0015095)
0.0	0.1	GO:0046935	1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.0	0.1	GO:0004937	alpha1-adrenergic receptor activity(GO:0004937)
0.0	0.1	GO:0004768	stearoyl-CoA 9-desaturase activity(GO:0004768) acyl-CoA desaturase activity(GO:0016215)
0.0	0.1	GO:0008321	Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.0	0.1	GO:0098847	single-stranded telomeric DNA binding(GO:0043047) sequence-specific single stranded DNA binding(GO:0098847)
0.0	0.1	GO:0004904	interferon receptor activity(GO:0004904)
0.0	0.1	GO:0005049	nuclear export signal receptor activity(GO:0005049)
0.0	0.1	GO:0004957	prostaglandin E receptor activity(GO:0004957)
0.0	0.1	GO:0004791	thioredoxin-disulfide reductase activity(GO:0004791)
0.0	0.1	GO:0004568	chitinase activity(GO:0004568)
0.0	0.1	GO:0050897	cobalt ion binding(GO:0050897)
0.0	0.1	GO:0005021	vascular endothelial growth factor-activated receptor activity(GO:0005021)
0.0	0.0	GO:0050544	arachidonic acid binding(GO:0050544)
0.0	0.1	GO:0005534	galactose binding(GO:0005534)
0.0	0.1	GO:0005110	frizzled-2 binding(GO:0005110)
0.0	0.1	GO:0015016	[heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
0.0	0.1	GO:0003688	DNA replication origin binding(GO:0003688)
0.0	0.0	GO:0016842	amidine-lyase activity(GO:0016842)
0.0	0.1	GO:0031624	ubiquitin conjugating enzyme binding(GO:0031624) ubiquitin-like protein conjugating enzyme binding(GO:0044390)
0.0	0.0	GO:0031544	procollagen-proline 3-dioxygenase activity(GO:0019797) peptidyl-proline 3-dioxygenase activity(GO:0031544)
0.0	0.2	GO:0070888	E-box binding(GO:0070888)
0.0	0.2	GO:0043498	obsolete cell surface binding(GO:0043498)
0.0	0.1	GO:0043522	leucine zipper domain binding(GO:0043522)
0.0	0.0	GO:0043734	DNA demethylase activity(GO:0035514) DNA-N1-methyladenine dioxygenase activity(GO:0043734)
0.0	0.0	GO:0008061	chitin binding(GO:0008061)
0.0	0.0	GO:0042608	T cell receptor binding(GO:0042608)
0.0	0.0	GO:0016901	oxidoreductase activity, acting on the CH-OH group of donors, quinone or similar compound as acceptor(GO:0016901)
0.0	0.0	GO:0003986	acetyl-CoA hydrolase activity(GO:0003986)

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.0	0.1	REACTOME PROSTANOID LIGAND RECEPTORS	Genes involved in Prostanoid ligand receptors
0.0	0.1	REACTOME CDC6 ASSOCIATION WITH THE ORC ORIGIN COMPLEX	Genes involved in CDC6 association with the ORC:origin complex