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ENCODE: H3K4me1 ChIP-Seq of primary human cells
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CREMA is a free online tool that recognizes most important transcription factors that change the chromatin state across different samples.

Results for PROX1

Z-value: 1.94

Motif logo

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Transcription factors associated with PROX1

Gene Symbol Gene ID Gene Info
ENSG00000117707.11 PROX1

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE Gene Distance Association probability Pearson corr. coef. P-value Plot
PROX1chr1_214157098_2141572496490.7139740.742.3e-02Click!
PROX1chr1_214156856_2141570074070.8524540.551.3e-01Click!
PROX1chr1_214162177_2141623684120.7941750.511.6e-01Click!
PROX1chr1_214161309_2141614791080.8350630.501.7e-01Click!
PROX1chr1_214161610_21416210620.9558820.481.9e-01Click!

Activity of the PROX1 motif across conditions

Conditions sorted by the z-value of the PROX1 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE) Target Score Top associated gene Gene Info Distance of CRE to TSS CRE/Gene association probability
chr1_25320280_25320441 0.91 RUNX3
runt-related transcription factor 3
28859
0.16
chr16_19728567_19728792 0.84 KNOP1
lysine-rich nucleolar protein 1
774
0.42
chr11_326229_326864 0.77 IFITM3
interferon induced transmembrane protein 3
991
0.28
chr11_114086673_114087539 0.77 NNMT
nicotinamide N-methyltransferase
41447
0.17
chr11_46352086_46352730 0.77 DGKZ
diacylglycerol kinase, zeta
2047
0.27
chr2_234329351_234329502 0.75 DGKD
diacylglycerol kinase, delta 130kDa
32626
0.14
chr14_22997541_22997805 0.71 TRAJ15
T cell receptor alpha joining 15
907
0.43
chr7_150324697_150324953 0.71 GIMAP6
GTPase, IMAP family member 6
4609
0.22
chr9_116283314_116283465 0.71 RGS3
regulator of G-protein signaling 3
3839
0.27
chr16_79303009_79303465 0.69 ENSG00000222244
.
4886
0.33
chr6_36077167_36077664 0.69 MAPK13
mitogen-activated protein kinase 13
20683
0.16
chr6_112126149_112126486 0.69 FYN
FYN oncogene related to SRC, FGR, YES
6691
0.3
chr8_128990046_128990302 0.67 ENSG00000221771
.
17295
0.16
chr18_13380419_13380663 0.67 LDLRAD4
low density lipoprotein receptor class A domain containing 4
2012
0.28
chr16_53551479_53551692 0.66 AKTIP
AKT interacting protein
13262
0.21
chr3_128480143_128480294 0.66 ENSG00000244232
.
23772
0.16
chr14_52368182_52368373 0.65 GNG2
guanine nucleotide binding protein (G protein), gamma 2
11553
0.17
chr11_128481294_128481657 0.65 ETS1
v-ets avian erythroblastosis virus E26 oncogene homolog 1
24022
0.2
chr10_5332260_5332573 0.64 AKR1C7P
aldo-keto reductase family 1, member C7, pseudogene
1983
0.35
chr4_40309280_40309495 0.63 CHRNA9
cholinergic receptor, nicotinic, alpha 9 (neuronal)
27959
0.19
chr10_11254490_11254686 0.61 RP3-323N1.2

41249
0.16
chr15_93357238_93357416 0.61 FAM174B
family with sequence similarity 174, member B
4299
0.19
chr3_15370184_15370338 0.61 SH3BP5
SH3-domain binding protein 5 (BTK-associated)
3806
0.17
chr7_50187399_50187568 0.61 AC020743.2

5064
0.25
chr2_25559592_25559774 0.60 DNMT3A
DNA (cytosine-5-)-methyltransferase 3 alpha
5071
0.23
chr14_99705171_99705454 0.59 AL109767.1

23973
0.19
chr7_157166465_157166616 0.58 DNAJB6
DnaJ (Hsp40) homolog, subfamily B, member 6
34025
0.19
chr12_11002723_11002874 0.58 PRR4
proline rich 4 (lacrimal)
724
0.56
chr9_378046_378197 0.58 DOCK8
dedicator of cytokinesis 8
11870
0.22
chr12_96770717_96770905 0.58 CDK17
cyclin-dependent kinase 17
22331
0.18
chr10_11183961_11184120 0.56 CELF2
CUGBP, Elav-like family member 2
22953
0.18
chr16_1609129_1609769 0.56 LA16c-425C2.1

20860
0.08
chr9_92032968_92033239 0.56 SEMA4D
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D
645
0.78
chr13_41207953_41208104 0.55 FOXO1
forkhead box O1
32706
0.19
chr2_74401509_74401660 0.55 MOB1A
MOB kinase activator 1A
1640
0.27
chr14_61902078_61902229 0.54 PRKCH
protein kinase C, eta
7123
0.26
chr2_29223353_29223504 0.54 FAM179A
family with sequence similarity 179, member A
17699
0.14
chr9_123467524_123467712 0.54 MEGF9
multiple EGF-like-domains 9
8994
0.26
chr1_25249924_25250075 0.54 RUNX3
runt-related transcription factor 3
5613
0.25
chr2_97579532_97579773 0.54 FAM178B
family with sequence similarity 178, member B
15782
0.14
chr9_36478011_36478162 0.53 RNF38
ring finger protein 38
76891
0.1
chr1_20511735_20512008 0.53 UBXN10
UBX domain protein 10
707
0.5
chr3_56952065_56952464 0.53 ARHGEF3
Rho guanine nucleotide exchange factor (GEF) 3
1765
0.42
chr1_101594560_101594920 0.52 ENSG00000252765
.
3969
0.25
chr12_107141176_107141327 0.52 RP11-482D24.3

14407
0.17
chr11_118801744_118801895 0.52 ENSG00000239726
.
101
0.92
chr20_5573948_5574171 0.52 GPCPD1
glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae)
17613
0.24
chr12_21766078_21766229 0.52 GYS2
glycogen synthase 2 (liver)
8372
0.2
chr8_129595182_129595552 0.52 ENSG00000221351
.
236673
0.02
chr17_7397267_7397418 0.52 POLR2A
polymerase (RNA) II (DNA directed) polypeptide A, 220kDa
9403
0.06
chr20_43609081_43609330 0.52 STK4
serine/threonine kinase 4
14038
0.14
chr1_231747664_231747892 0.52 LINC00582
long intergenic non-protein coding RNA 582
58
0.98
chr14_97924480_97924631 0.52 ENSG00000240730
.
71955
0.14
chr4_40303302_40303674 0.51 CHRNA9
cholinergic receptor, nicotinic, alpha 9 (neuronal)
33858
0.17
chr9_117668023_117668209 0.51 TNFSF8
tumor necrosis factor (ligand) superfamily, member 8
24581
0.23
chr15_91116536_91116733 0.51 CRTC3
CREB regulated transcription coactivator 3
20311
0.15
chr3_58100941_58101092 0.51 FLNB
filamin B, beta
34577
0.17
chr18_60955745_60955940 0.51 RP11-28F1.2

25473
0.16
chr21_40347343_40347494 0.51 ENSG00000272015
.
80709
0.1
chr11_6769233_6769567 0.51 OR2AG2
olfactory receptor, family 2, subfamily AG, member 2
20886
0.11
chr12_65025633_65025886 0.51 RP11-338E21.2

3635
0.16
chr1_77746575_77746817 0.51 AK5
adenylate kinase 5
1040
0.61
chr12_121530141_121530589 0.51 ENSG00000201945
.
14481
0.16
chr1_42382630_42382984 0.51 HIVEP3
human immunodeficiency virus type I enhancer binding protein 3
1362
0.59
chrX_147391495_147391734 0.51 AC002368.4

190521
0.03
chr7_150183670_150183944 0.50 GIMAP7
GTPase, IMAP family member 7
28111
0.14
chr11_68233185_68233560 0.50 PPP6R3
protein phosphatase 6, regulatory subunit 3
5091
0.2
chr11_73729911_73730186 0.50 UCP3
uncoupling protein 3 (mitochondrial, proton carrier)
9568
0.16
chr14_64204068_64204219 0.50 ENSG00000252749
.
981
0.54
chr1_112045793_112046152 0.50 ADORA3
adenosine A3 receptor
138
0.93
chr16_3510818_3510980 0.50 NAA60
N(alpha)-acetyltransferase 60, NatF catalytic subunit
2769
0.18
chr2_136887722_136888188 0.49 CXCR4
chemokine (C-X-C motif) receptor 4
12220
0.28
chr7_50429911_50430494 0.49 IKZF1
IKAROS family zinc finger 1 (Ikaros)
62957
0.12
chr4_122113271_122113718 0.49 ENSG00000252183
.
564
0.8
chr15_44964229_44964380 0.49 PATL2
protein associated with topoisomerase II homolog 2 (yeast)
3621
0.18
chrX_44821643_44821794 0.49 ENSG00000252113
.
76967
0.1
chr7_142045451_142045602 0.48 PRSS3P3
protease, serine, 3 pseudogene 3
55917
0.14
chr6_1537339_1537490 0.48 ENSG00000243439
.
29857
0.22
chr16_12103610_12103841 0.48 RP11-166B2.7

32018
0.1
chr1_33337573_33337724 0.48 FNDC5
fibronectin type III domain containing 5
433
0.77
chr20_31557233_31557384 0.47 EFCAB8
EF-hand calcium binding domain 8
9657
0.16
chr19_16480711_16480862 0.47 EPS15L1
epidermal growth factor receptor pathway substrate 15-like 1
8022
0.15
chrX_19761612_19761864 0.47 SH3KBP1
SH3-domain kinase binding protein 1
2783
0.4
chr4_109081453_109081912 0.47 LEF1
lymphoid enhancer-binding factor 1
5775
0.24
chr14_65237977_65238128 0.47 SPTB
spectrin, beta, erythrocytic
11216
0.2
chr19_3970402_3970671 0.47 DAPK3
death-associated protein kinase 3
86
0.94
chr12_120512187_120512338 0.47 CCDC64
coiled-coil domain containing 64
2755
0.23
chr13_24841056_24841207 0.47 SPATA13
spermatogenesis associated 13
3695
0.21
chr12_42737573_42737724 0.47 PPHLN1
periphilin 1
42
0.97
chr5_145589313_145589581 0.47 RBM27
RNA binding motif protein 27
6284
0.21
chr8_2092796_2092947 0.47 MYOM2
myomesin 2
99687
0.08
chr3_71508207_71508358 0.47 ENSG00000221264
.
82958
0.09
chr17_72365655_72365843 0.46 GPR142
G protein-coupled receptor 142
2152
0.2
chr5_56121216_56121683 0.46 MAP3K1
mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase
10048
0.18
chr10_120457476_120457627 0.46 CACUL1
CDK2-associated, cullin domain 1
57207
0.12
chr6_154478833_154479416 0.46 OPRM1
opioid receptor, mu 1
71482
0.12
chr6_45463124_45463523 0.46 RUNX2
runt-related transcription factor 2
73101
0.11
chr5_139030210_139030361 0.46 CXXC5
CXXC finger protein 5
289
0.92
chr11_104480366_104480593 0.46 CASP12
caspase 12 (gene/pseudogene)
288662
0.01
chr13_40670767_40671082 0.45 ENSG00000207458
.
130040
0.06
chr4_123379067_123379218 0.45 IL2
interleukin 2
1262
0.57
chr7_150019104_150019348 0.45 ACTR3C
ARP3 actin-related protein 3 homolog C (yeast)
1026
0.31
chr2_106777844_106778093 0.45 UXS1
UDP-glucuronate decarboxylase 1
887
0.66
chr19_42632588_42632877 0.45 POU2F2
POU class 2 homeobox 2
3811
0.11
chr4_154422696_154422847 0.45 KIAA0922
KIAA0922
35270
0.19
chr6_134495408_134495587 0.45 SGK1
serum/glucocorticoid regulated kinase 1
505
0.81
chr3_71274197_71274348 0.45 FOXP1
forkhead box P1
20044
0.26
chr8_20112422_20112573 0.45 LZTS1
leucine zipper, putative tumor suppressor 1
195
0.94
chr15_93632692_93632897 0.45 RGMA
repulsive guidance molecule family member a
361
0.92
chr2_45478028_45478179 0.45 SIX2
SIX homeobox 2
241534
0.02
chr1_93422949_93423110 0.45 FAM69A
family with sequence similarity 69, member A
4028
0.15
chr14_106327072_106327522 0.45 ENSG00000265714
.
1273
0.08
chr22_31981049_31981318 0.44 SFI1
Sfi1 homolog, spindle assembly associated (yeast)
1291
0.46
chr3_177662901_177663156 0.44 ENSG00000199858
.
62539
0.16
chr16_53544613_53544883 0.44 AKTIP
AKT interacting protein
6425
0.23
chr21_34103959_34104195 0.44 PAXBP1-AS1
PAXBP1 antisense RNA 1
1414
0.35
chr3_71352722_71352944 0.44 FOXP1
forkhead box P1
1078
0.61
chr21_43846854_43847005 0.44 ENSG00000252619
.
9227
0.14
chr2_162852542_162852808 0.44 AC008063.2

77091
0.09
chr4_26961356_26961595 0.44 STIM2
stromal interaction molecule 2
43147
0.2
chrX_9592027_9592178 0.43 TBL1X
transducin (beta)-like 1X-linked
89119
0.09
chr1_200838727_200838878 0.43 GPR25
G protein-coupled receptor 25
3281
0.23
chr14_65905383_65905557 0.43 FUT8
fucosyltransferase 8 (alpha (1,6) fucosyltransferase)
25730
0.2
chr17_35031754_35032157 0.43 MRM1
mitochondrial rRNA methyltransferase 1 homolog (S. cerevisiae)
73564
0.08
chr12_12772516_12772715 0.43 CREBL2
cAMP responsive element binding protein-like 2
7789
0.21
chr1_52083477_52083692 0.43 OSBPL9
oxysterol binding protein-like 9
803
0.68
chr17_73121977_73122246 0.43 NT5C
5', 3'-nucleotidase, cytosolic
5242
0.09
chr4_154415639_154415790 0.43 KIAA0922
KIAA0922
28213
0.21
chr1_161158279_161158521 0.43 ADAMTS4
ADAM metallopeptidase with thrombospondin type 1 motif, 4
10443
0.06
chr4_153000114_153000345 0.43 ENSG00000253077
.
107464
0.07
chr2_240524112_240524372 0.43 AC079612.1
Uncharacterized protein; cDNA FLJ45964 fis, clone PLACE7014396
24247
0.25
chr2_61758031_61758408 0.43 XPO1
exportin 1 (CRM1 homolog, yeast)
3194
0.24
chr2_97628467_97628722 0.43 ENSG00000252845
.
6042
0.16
chr16_3838912_3839326 0.43 CREBBP
CREB binding protein
8251
0.23
chr19_17433702_17433886 0.43 ANO8
anoctamin 8
11844
0.07
chr4_7832948_7833099 0.42 AFAP1
actin filament associated protein 1
40786
0.16
chr5_150631607_150631777 0.42 GM2A
GM2 ganglioside activator
761
0.65
chr19_11664816_11664967 0.42 ELOF1
elongation factor 1 homolog (S. cerevisiae)
718
0.48
chr6_166747055_166747348 0.42 SFT2D1
SFT2 domain containing 1
8878
0.19
chrX_24666059_24666265 0.42 PCYT1B
phosphate cytidylyltransferase 1, choline, beta
809
0.56
chr20_31260771_31260928 0.42 COMMD7
COMM domain containing 7
70363
0.08
chr14_55839531_55839755 0.42 RP11-665C16.5

33424
0.16
chr2_175359311_175359644 0.42 GPR155
G protein-coupled receptor 155
7655
0.2
chr8_99956958_99957335 0.42 OSR2
odd-skipped related transciption factor 2
259
0.9
chr20_1344489_1344952 0.42 RP11-314N13.3

2454
0.22
chr7_76980036_76980207 0.42 GSAP
gamma-secretase activating protein
20437
0.22
chr8_19367752_19367981 0.42 CSGALNACT1
chondroitin sulfate N-acetylgalactosaminyltransferase 1
91510
0.1
chr1_101774544_101774731 0.42 RP4-575N6.5

65923
0.1
chr8_129670035_129670289 0.42 ENSG00000221351
.
161878
0.04
chr6_2023671_2023822 0.42 GMDS
GDP-mannose 4,6-dehydratase
152479
0.04
chr22_20005369_20005520 0.41 TANGO2
transport and golgi organization 2 homolog (Drosophila)
890
0.34
chr2_28475686_28475837 0.41 AC093690.1

57565
0.14
chr1_151027461_151027678 0.41 MLLT11
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
2665
0.12
chr6_43244325_43244476 0.41 SLC22A7
solute carrier family 22 (organic anion transporter), member 7
21336
0.11
chr4_143622207_143622596 0.41 INPP4B
inositol polyphosphate-4-phosphatase, type II, 105kDa
140579
0.05
chr10_70384861_70385507 0.41 TET1
tet methylcytosine dioxygenase 1
64771
0.08
chr1_231746267_231746480 0.41 LINC00582
long intergenic non-protein coding RNA 582
1463
0.42
chr19_19718141_19718292 0.41 AC002306.1

1057
0.38
chr13_99911653_99911895 0.41 GPR18
G protein-coupled receptor 18
1092
0.53
chr3_51711887_51712231 0.41 TEX264
testis expressed 264
6148
0.16
chr17_14093316_14093554 0.41 ENSG00000252305
.
12987
0.2
chr2_162928731_162929065 0.41 AC008063.2

868
0.58
chr8_121743626_121743819 0.41 RP11-713M15.1

29771
0.22
chr2_145085983_145086134 0.41 GTDC1
glycosyltransferase-like domain containing 1
4025
0.35
chr22_23793387_23793538 0.41 ZDHHC8P1
zinc finger, DHHC-type containing 8 pseudogene 1
49118
0.12
chr3_87842915_87843066 0.41 ENSG00000200703
.
51191
0.17
chr11_6459562_6459838 0.41 HPX
hemopexin
2594
0.18
chr11_12165537_12165696 0.41 MICAL2
microtubule associated monooxygenase, calponin and LIM domain containing 2
5646
0.3
chr12_68759301_68759452 0.40 MDM1
Mdm1 nuclear protein homolog (mouse)
33215
0.21
chr12_65008891_65009217 0.40 RASSF3
Ras association (RalGDS/AF-6) domain family member 3
4761
0.14
chr3_17049819_17049970 0.40 PLCL2
phospholipase C-like 2
2092
0.39
chrX_123529862_123530058 0.40 SH2D1A
SH2 domain containing 1A
49521
0.19
chr6_144675907_144676058 0.40 UTRN
utrophin
10745
0.25
chr14_102818626_102818777 0.40 ENSG00000239061
.
6538
0.13
chr4_109056844_109057272 0.40 LEF1
lymphoid enhancer-binding factor 1
30399
0.19
chr2_196396233_196396389 0.40 ENSG00000202206
.
17551
0.25
chr16_3623403_3623748 0.40 NLRC3
NLR family, CARD domain containing 3
3817
0.17
chr7_132938245_132938484 0.40 EXOC4
exocyst complex component 4
236
0.95
chr11_63307656_63307807 0.40 RARRES3
retinoic acid receptor responder (tazarotene induced) 3
1863
0.28
chr3_71530793_71531298 0.40 ENSG00000221264
.
60195
0.13
chr1_208055973_208056124 0.40 CD34
CD34 molecule
7789
0.29
chr6_157246079_157246230 0.40 ARID1B
AT rich interactive domain 1B (SWI1-like)
23647
0.26
chr14_57527452_57527603 0.40 AL391152.1

144361
0.04
chr12_88433053_88433204 0.40 C12orf29
chromosome 12 open reading frame 29
3905
0.22
chr20_42649596_42649747 0.40 ENSG00000241229
.
13783
0.22
chr6_71382388_71382539 0.40 SMAP1
small ArfGAP 1
4842
0.32
chr14_78219731_78219882 0.39 C14orf178
chromosome 14 open reading frame 178
7367
0.14
chr10_97531333_97531484 0.39 ENTPD1
ectonucleoside triphosphate diphosphohydrolase 1
15694
0.21
chr10_11248795_11249171 0.39 RP3-323N1.2

35644
0.17
chr1_169640913_169641224 0.39 SELL
selectin L
39771
0.13
chr16_71828949_71829476 0.39 AP1G1
adaptor-related protein complex 1, gamma 1 subunit
12985
0.13
chr6_114287058_114287209 0.39 HDAC2
histone deacetylase 2
2561
0.27
chr1_31215274_31215425 0.39 ENSG00000264773
.
3270
0.2
chr17_16920000_16920415 0.39 MPRIP
myosin phosphatase Rho interacting protein
25652
0.15
chr15_43444066_43444217 0.39 TMEM62
transmembrane protein 62
17661
0.14
chr16_27389354_27389583 0.39 IL21R
interleukin 21 receptor
24015
0.17
chr16_3858533_3859115 0.39 CREBBP
CREB binding protein
27956
0.18
chr9_123607204_123607355 0.39 PSMD5-AS1
PSMD5 antisense RNA 1 (head to head)
127
0.95
chr15_31561641_31561994 0.39 KLF13
Kruppel-like factor 13
57241
0.15
chr14_90217677_90217828 0.39 ENSG00000200312
.
38897
0.17

Histogram of CRE-TSS distances for CREs targeted by :

Histogram of

Rank distribution of CRE target scores:

Histogram of target CRE score.

Distribution of target CREs across different genomic regions:

Weighted Piechart of Weighted Piechart of Weighted Piechart of

Network of associatons between targets according to the STRING database.

StringDB image

First level regulatory network of PROX1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.8 GO:0033152 immunoglobulin V(D)J recombination(GO:0033152)
0.1 0.6 GO:0030854 positive regulation of granulocyte differentiation(GO:0030854)
0.1 0.4 GO:0001831 trophectodermal cellular morphogenesis(GO:0001831)
0.1 0.4 GO:0046548 retinal rod cell development(GO:0046548)
0.1 0.9 GO:0045066 regulatory T cell differentiation(GO:0045066)
0.1 0.4 GO:0042091 interleukin-10 biosynthetic process(GO:0042091) regulation of interleukin-10 biosynthetic process(GO:0045074)
0.1 0.5 GO:0061029 eyelid development in camera-type eye(GO:0061029)
0.1 0.1 GO:0002326 B cell lineage commitment(GO:0002326)
0.1 0.3 GO:0018076 N-terminal peptidyl-lysine acetylation(GO:0018076)
0.1 0.4 GO:0006689 ganglioside catabolic process(GO:0006689)
0.1 0.4 GO:0002691 regulation of cellular extravasation(GO:0002691)
0.1 0.5 GO:0045898 regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045898)
0.1 0.3 GO:0006922 obsolete cleavage of lamin involved in execution phase of apoptosis(GO:0006922)
0.1 0.3 GO:0010040 response to iron(II) ion(GO:0010040)
0.1 0.3 GO:0045722 positive regulation of gluconeogenesis(GO:0045722)
0.1 0.3 GO:0021869 forebrain ventricular zone progenitor cell division(GO:0021869)
0.1 0.3 GO:0017121 phospholipid scrambling(GO:0017121)
0.1 0.1 GO:0002523 leukocyte migration involved in inflammatory response(GO:0002523)
0.1 0.2 GO:0009189 deoxyribonucleoside diphosphate biosynthetic process(GO:0009189)
0.1 0.3 GO:0060632 regulation of microtubule-based movement(GO:0060632)
0.1 0.3 GO:0060088 auditory receptor cell morphogenesis(GO:0002093) auditory receptor cell stereocilium organization(GO:0060088)
0.1 0.2 GO:0007000 nucleolus organization(GO:0007000)
0.1 0.3 GO:0022614 membrane to membrane docking(GO:0022614)
0.1 0.2 GO:0060136 embryonic process involved in female pregnancy(GO:0060136)
0.1 0.3 GO:0042635 positive regulation of hair cycle(GO:0042635) positive regulation of hair follicle development(GO:0051798)
0.1 0.3 GO:0006346 methylation-dependent chromatin silencing(GO:0006346)
0.1 0.1 GO:0010916 regulation of very-low-density lipoprotein particle clearance(GO:0010915) negative regulation of very-low-density lipoprotein particle clearance(GO:0010916)
0.1 0.4 GO:0085020 protein K6-linked ubiquitination(GO:0085020)
0.1 0.2 GO:0060394 negative regulation of pathway-restricted SMAD protein phosphorylation(GO:0060394)
0.1 0.2 GO:0070601 centromeric sister chromatid cohesion(GO:0070601) regulation of centromeric sister chromatid cohesion(GO:0070602)
0.1 0.6 GO:0045022 early endosome to late endosome transport(GO:0045022) vesicle-mediated transport between endosomal compartments(GO:0098927)
0.1 0.3 GO:0002710 negative regulation of T cell mediated immunity(GO:0002710)
0.1 0.2 GO:0034392 negative regulation of smooth muscle cell apoptotic process(GO:0034392)
0.1 0.5 GO:0006491 N-glycan processing(GO:0006491)
0.1 0.2 GO:0019276 UDP-N-acetylgalactosamine metabolic process(GO:0019276)
0.1 0.3 GO:0016556 mRNA modification(GO:0016556)
0.1 0.2 GO:0002830 positive regulation of type 2 immune response(GO:0002830)
0.1 0.5 GO:0007172 signal complex assembly(GO:0007172)
0.1 0.3 GO:0019987 obsolete negative regulation of anti-apoptosis(GO:0019987)
0.1 0.2 GO:0006391 transcription initiation from mitochondrial promoter(GO:0006391)
0.1 0.3 GO:0070670 response to interleukin-4(GO:0070670)
0.1 0.2 GO:0042504 tyrosine phosphorylation of Stat4 protein(GO:0042504) regulation of tyrosine phosphorylation of Stat4 protein(GO:0042519) positive regulation of tyrosine phosphorylation of Stat4 protein(GO:0042520)
0.1 0.2 GO:0061030 epithelial cell differentiation involved in mammary gland alveolus development(GO:0061030)
0.1 0.2 GO:0002335 mature B cell differentiation(GO:0002335)
0.1 0.4 GO:0060216 definitive hemopoiesis(GO:0060216)
0.1 0.7 GO:0045648 positive regulation of erythrocyte differentiation(GO:0045648)
0.1 0.3 GO:0051593 response to folic acid(GO:0051593)
0.1 0.2 GO:0034063 stress granule assembly(GO:0034063)
0.1 0.2 GO:0045348 positive regulation of MHC class II biosynthetic process(GO:0045348)
0.1 0.3 GO:0042535 positive regulation of tumor necrosis factor biosynthetic process(GO:0042535)
0.1 0.2 GO:0035405 histone-threonine phosphorylation(GO:0035405)
0.1 0.2 GO:0071481 cellular response to X-ray(GO:0071481)
0.1 0.2 GO:0015015 heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.1 0.2 GO:0051657 maintenance of organelle location(GO:0051657)
0.0 0.0 GO:0071801 regulation of podosome assembly(GO:0071801) positive regulation of podosome assembly(GO:0071803)
0.0 0.1 GO:0051152 positive regulation of smooth muscle cell differentiation(GO:0051152)
0.0 0.1 GO:0002902 B cell apoptotic process(GO:0001783) regulation of B cell apoptotic process(GO:0002902)
0.0 0.2 GO:0008053 mitochondrial fusion(GO:0008053)
0.0 0.1 GO:0032506 cytokinetic process(GO:0032506)
0.0 0.1 GO:0045343 MHC class I biosynthetic process(GO:0045341) regulation of MHC class I biosynthetic process(GO:0045343)
0.0 0.1 GO:0050862 positive regulation of T cell receptor signaling pathway(GO:0050862)
0.0 0.1 GO:0032914 positive regulation of transforming growth factor beta1 production(GO:0032914)
0.0 0.1 GO:0040016 embryonic cleavage(GO:0040016)
0.0 0.6 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.0 0.2 GO:0006591 ornithine metabolic process(GO:0006591)
0.0 0.6 GO:0006385 transcription elongation from RNA polymerase III promoter(GO:0006385) termination of RNA polymerase III transcription(GO:0006386)
0.0 0.0 GO:0003402 planar cell polarity pathway involved in axis elongation(GO:0003402)
0.0 0.1 GO:0010761 fibroblast migration(GO:0010761)
0.0 0.1 GO:0046642 negative regulation of alpha-beta T cell proliferation(GO:0046642)
0.0 0.2 GO:0048548 regulation of pinocytosis(GO:0048548)
0.0 0.3 GO:0050710 negative regulation of cytokine secretion(GO:0050710)
0.0 0.1 GO:0016553 base conversion or substitution editing(GO:0016553)
0.0 0.2 GO:0002726 positive regulation of T cell cytokine production(GO:0002726)
0.0 0.2 GO:0090400 stress-induced premature senescence(GO:0090400)
0.0 0.2 GO:1901339 activation of store-operated calcium channel activity(GO:0032237) regulation of store-operated calcium channel activity(GO:1901339) positive regulation of store-operated calcium channel activity(GO:1901341)
0.0 0.2 GO:0043457 regulation of cellular respiration(GO:0043457)
0.0 0.2 GO:0031936 negative regulation of chromatin silencing(GO:0031936)
0.0 0.2 GO:0048261 negative regulation of receptor-mediated endocytosis(GO:0048261)
0.0 0.2 GO:0007256 activation of JNKK activity(GO:0007256)
0.0 0.0 GO:2000188 regulation of cholesterol homeostasis(GO:2000188) positive regulation of cholesterol homeostasis(GO:2000189)
0.0 0.1 GO:0090382 phagolysosome assembly(GO:0001845) phagosome maturation(GO:0090382)
0.0 0.2 GO:0042761 very long-chain fatty acid biosynthetic process(GO:0042761)
0.0 0.1 GO:0030011 maintenance of cell polarity(GO:0030011)
0.0 0.2 GO:0032367 intracellular sterol transport(GO:0032366) intracellular cholesterol transport(GO:0032367)
0.0 0.1 GO:0008054 negative regulation of cyclin-dependent protein serine/threonine kinase by cyclin degradation(GO:0008054)
0.0 0.1 GO:0060596 mammary placode formation(GO:0060596)
0.0 0.2 GO:0032667 interleukin-23 production(GO:0032627) regulation of interleukin-23 production(GO:0032667) positive regulation of interleukin-23 production(GO:0032747)
0.0 0.3 GO:0006198 cAMP catabolic process(GO:0006198)
0.0 0.2 GO:0042104 positive regulation of activated T cell proliferation(GO:0042104)
0.0 0.2 GO:0043368 positive T cell selection(GO:0043368)
0.0 0.3 GO:0044091 membrane biogenesis(GO:0044091)
0.0 0.0 GO:0045945 positive regulation of transcription from RNA polymerase III promoter(GO:0045945)
0.0 0.3 GO:0043508 negative regulation of JUN kinase activity(GO:0043508)
0.0 0.2 GO:0010759 positive regulation of macrophage chemotaxis(GO:0010759)
0.0 0.1 GO:0002925 positive regulation of humoral immune response mediated by circulating immunoglobulin(GO:0002925)
0.0 0.1 GO:0035609 C-terminal protein deglutamylation(GO:0035609) protein side chain deglutamylation(GO:0035610)
0.0 0.1 GO:0090322 regulation of superoxide metabolic process(GO:0090322)
0.0 0.3 GO:0070076 histone lysine demethylation(GO:0070076)
0.0 0.3 GO:0043550 regulation of lipid kinase activity(GO:0043550)
0.0 0.1 GO:0045767 obsolete regulation of anti-apoptosis(GO:0045767)
0.0 0.1 GO:0033522 histone H2A ubiquitination(GO:0033522)
0.0 0.2 GO:0032099 negative regulation of appetite(GO:0032099)
0.0 0.1 GO:0032790 ribosome disassembly(GO:0032790)
0.0 0.1 GO:0060124 positive regulation of growth hormone secretion(GO:0060124)
0.0 0.1 GO:0040015 negative regulation of multicellular organism growth(GO:0040015)
0.0 0.2 GO:0046719 intracellular transport of viral protein in host cell(GO:0019060) symbiont intracellular protein transport in host(GO:0030581) regulation by virus of viral protein levels in host cell(GO:0046719) intracellular protein transport in other organism involved in symbiotic interaction(GO:0051708)
0.0 0.1 GO:0010957 negative regulation of calcidiol 1-monooxygenase activity(GO:0010956) negative regulation of vitamin D biosynthetic process(GO:0010957) negative regulation of vitamin metabolic process(GO:0046137)
0.0 0.1 GO:0001766 membrane raft polarization(GO:0001766) membrane raft distribution(GO:0031580)
0.0 0.1 GO:0032966 negative regulation of collagen biosynthetic process(GO:0032966)
0.0 0.0 GO:0061154 endothelial tube morphogenesis(GO:0061154)
0.0 0.1 GO:0003100 regulation of systemic arterial blood pressure by endothelin(GO:0003100)
0.0 0.1 GO:0006686 sphingomyelin biosynthetic process(GO:0006686)
0.0 0.1 GO:0035305 negative regulation of dephosphorylation(GO:0035305) negative regulation of protein dephosphorylation(GO:0035308)
0.0 0.1 GO:0071428 rRNA-containing ribonucleoprotein complex export from nucleus(GO:0071428)
0.0 0.1 GO:0001778 plasma membrane repair(GO:0001778)
0.0 0.1 GO:0061298 retina vasculature development in camera-type eye(GO:0061298) retina vasculature morphogenesis in camera-type eye(GO:0061299)
0.0 0.1 GO:0045112 integrin biosynthetic process(GO:0045112)
0.0 0.1 GO:0006384 transcription initiation from RNA polymerase III promoter(GO:0006384)
0.0 0.1 GO:0033632 regulation of cell-cell adhesion mediated by integrin(GO:0033632)
0.0 0.8 GO:0050690 regulation of defense response to virus by virus(GO:0050690)
0.0 0.0 GO:0022030 cerebral cortex radial glia guided migration(GO:0021801) telencephalon glial cell migration(GO:0022030)
0.0 0.0 GO:0002227 innate immune response in mucosa(GO:0002227) mucosal immune response(GO:0002385)
0.0 0.1 GO:0031558 obsolete induction of apoptosis in response to chemical stimulus(GO:0031558)
0.0 0.1 GO:0030812 negative regulation of nucleotide catabolic process(GO:0030812)
0.0 0.1 GO:0042416 dopamine biosynthetic process(GO:0042416)
0.0 0.1 GO:0097576 vacuole fusion(GO:0097576)
0.0 0.1 GO:0060662 tube lumen cavitation(GO:0060605) salivary gland cavitation(GO:0060662)
0.0 0.1 GO:0045292 mRNA cis splicing, via spliceosome(GO:0045292)
0.0 0.1 GO:0010642 negative regulation of platelet-derived growth factor receptor signaling pathway(GO:0010642)
0.0 0.1 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
0.0 0.3 GO:0043666 regulation of phosphoprotein phosphatase activity(GO:0043666)
0.0 0.1 GO:0010587 miRNA metabolic process(GO:0010586) miRNA catabolic process(GO:0010587)
0.0 0.1 GO:0017183 peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183)
0.0 0.0 GO:0032661 interleukin-18 production(GO:0032621) regulation of interleukin-18 production(GO:0032661)
0.0 0.1 GO:0060710 chorio-allantoic fusion(GO:0060710)
0.0 0.3 GO:0019059 obsolete initiation of viral infection(GO:0019059)
0.0 0.1 GO:0019885 antigen processing and presentation of endogenous peptide antigen(GO:0002483) antigen processing and presentation of endogenous peptide antigen via MHC class I(GO:0019885)
0.0 0.2 GO:0035434 copper ion transmembrane transport(GO:0035434)
0.0 0.2 GO:0043558 regulation of translational initiation in response to stress(GO:0043558)
0.0 0.1 GO:0019372 lipoxygenase pathway(GO:0019372)
0.0 0.1 GO:0070682 proteasome regulatory particle assembly(GO:0070682)
0.0 0.1 GO:0006189 'de novo' IMP biosynthetic process(GO:0006189)
0.0 0.2 GO:0060158 phospholipase C-activating dopamine receptor signaling pathway(GO:0060158)
0.0 0.1 GO:0006930 substrate-dependent cell migration, cell extension(GO:0006930)
0.0 0.1 GO:0006998 nuclear envelope organization(GO:0006998)
0.0 0.2 GO:0006538 glutamate catabolic process(GO:0006538)
0.0 0.1 GO:0000012 single strand break repair(GO:0000012)
0.0 0.1 GO:0048096 chromatin-mediated maintenance of transcription(GO:0048096)
0.0 0.0 GO:0009214 cyclic nucleotide catabolic process(GO:0009214)
0.0 0.1 GO:0009296 obsolete flagellum assembly(GO:0009296)
0.0 0.2 GO:0045822 negative regulation of heart contraction(GO:0045822)
0.0 0.1 GO:0032100 positive regulation of response to food(GO:0032097) positive regulation of appetite(GO:0032100)
0.0 0.1 GO:0071392 cellular response to estradiol stimulus(GO:0071392)
0.0 0.1 GO:0000729 DNA double-strand break processing(GO:0000729)
0.0 0.0 GO:0001302 replicative cell aging(GO:0001302)
0.0 0.1 GO:0001705 ectoderm formation(GO:0001705)
0.0 0.1 GO:0007097 nuclear migration(GO:0007097)
0.0 0.2 GO:0006002 fructose 6-phosphate metabolic process(GO:0006002)
0.0 0.2 GO:0043568 positive regulation of insulin-like growth factor receptor signaling pathway(GO:0043568)
0.0 0.1 GO:1901522 positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus(GO:1901522)
0.0 0.1 GO:0032922 circadian regulation of gene expression(GO:0032922)
0.0 0.1 GO:0007008 outer mitochondrial membrane organization(GO:0007008) protein import into mitochondrial outer membrane(GO:0045040)
0.0 0.1 GO:0001661 conditioned taste aversion(GO:0001661)
0.0 0.2 GO:0000303 response to superoxide(GO:0000303)
0.0 0.1 GO:1902745 positive regulation of lamellipodium assembly(GO:0010592) positive regulation of lamellipodium organization(GO:1902745)
0.0 0.1 GO:0021754 facial nucleus development(GO:0021754)
0.0 0.2 GO:0006349 regulation of gene expression by genetic imprinting(GO:0006349)
0.0 0.0 GO:0070254 mucus secretion(GO:0070254)
0.0 0.1 GO:0007035 vacuolar acidification(GO:0007035)
0.0 0.1 GO:0045875 negative regulation of sister chromatid cohesion(GO:0045875)
0.0 0.1 GO:0018027 peptidyl-lysine dimethylation(GO:0018027)
0.0 0.3 GO:0031146 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process(GO:0031146)
0.0 0.5 GO:0007190 activation of adenylate cyclase activity(GO:0007190)
0.0 0.0 GO:0045672 positive regulation of osteoclast differentiation(GO:0045672)
0.0 0.1 GO:0000301 retrograde transport, vesicle recycling within Golgi(GO:0000301)
0.0 0.1 GO:0006420 arginyl-tRNA aminoacylation(GO:0006420)
0.0 0.1 GO:0015917 aminophospholipid transport(GO:0015917)
0.0 0.1 GO:0034616 response to laminar fluid shear stress(GO:0034616)
0.0 0.1 GO:0006929 substrate-dependent cell migration(GO:0006929)
0.0 0.0 GO:0042109 lymphotoxin A production(GO:0032641) lymphotoxin A biosynthetic process(GO:0042109)
0.0 0.2 GO:1903078 positive regulation of establishment of protein localization to plasma membrane(GO:0090004) positive regulation of protein localization to plasma membrane(GO:1903078) positive regulation of protein localization to cell periphery(GO:1904377)
0.0 0.4 GO:0033209 tumor necrosis factor-mediated signaling pathway(GO:0033209)
0.0 0.1 GO:0000103 sulfate assimilation(GO:0000103)
0.0 0.0 GO:0043951 negative regulation of cAMP-mediated signaling(GO:0043951)
0.0 0.2 GO:0000050 urea cycle(GO:0000050)
0.0 0.1 GO:0071549 cellular response to dexamethasone stimulus(GO:0071549)
0.0 0.0 GO:0021570 rhombomere 4 development(GO:0021570)
0.0 0.2 GO:0048205 COPI-coated vesicle budding(GO:0035964) Golgi vesicle budding(GO:0048194) Golgi transport vesicle coating(GO:0048200) COPI coating of Golgi vesicle(GO:0048205)
0.0 0.2 GO:0030206 chondroitin sulfate biosynthetic process(GO:0030206)
0.0 0.0 GO:0046940 nucleoside monophosphate phosphorylation(GO:0046940)
0.0 0.0 GO:0010831 positive regulation of myotube differentiation(GO:0010831)
0.0 0.2 GO:0006657 CDP-choline pathway(GO:0006657)
0.0 0.3 GO:0032012 regulation of ARF protein signal transduction(GO:0032012)
0.0 0.1 GO:0006290 pyrimidine dimer repair(GO:0006290)
0.0 0.1 GO:0033962 cytoplasmic mRNA processing body assembly(GO:0033962)
0.0 0.1 GO:1904181 positive regulation of mitochondrial depolarization(GO:0051901) positive regulation of membrane depolarization(GO:1904181)
0.0 0.2 GO:1905144 G-protein coupled acetylcholine receptor signaling pathway(GO:0007213) cellular response to ammonium ion(GO:0071242) acetylcholine receptor signaling pathway(GO:0095500) postsynaptic signal transduction(GO:0098926) signal transduction involved in cellular response to ammonium ion(GO:1903831) response to acetylcholine(GO:1905144) cellular response to acetylcholine(GO:1905145)
0.0 0.1 GO:0045793 positive regulation of cell size(GO:0045793)
0.0 0.2 GO:0046519 sphingoid metabolic process(GO:0046519)
0.0 0.1 GO:0006390 mitochondrial RNA metabolic process(GO:0000959) transcription from mitochondrial promoter(GO:0006390)
0.0 0.1 GO:0042117 monocyte activation(GO:0042117)
0.0 0.0 GO:0032098 regulation of appetite(GO:0032098)
0.0 0.2 GO:0044766 multi-organism transport(GO:0044766) transport of virus(GO:0046794) intracellular transport of virus(GO:0075733) multi-organism localization(GO:1902579) multi-organism intracellular transport(GO:1902583)
0.0 0.1 GO:0030186 melatonin metabolic process(GO:0030186) melatonin biosynthetic process(GO:0030187)
0.0 0.1 GO:0042989 sequestering of actin monomers(GO:0042989)
0.0 0.3 GO:0042273 ribosomal large subunit biogenesis(GO:0042273)
0.0 0.0 GO:0030505 inorganic diphosphate transport(GO:0030505)
0.0 0.1 GO:0051085 chaperone mediated protein folding requiring cofactor(GO:0051085)
0.0 0.3 GO:0046834 lipid phosphorylation(GO:0046834)
0.0 0.0 GO:0060084 synaptic transmission involved in micturition(GO:0060084)
0.0 0.0 GO:0097709 connective tissue replacement involved in inflammatory response wound healing(GO:0002248) connective tissue replacement(GO:0097709)
0.0 0.1 GO:0032876 regulation of DNA endoreduplication(GO:0032875) negative regulation of DNA endoreduplication(GO:0032876) DNA endoreduplication(GO:0042023)
0.0 0.1 GO:0048013 ephrin receptor signaling pathway(GO:0048013)
0.0 0.1 GO:0008354 germ cell migration(GO:0008354)
0.0 0.0 GO:0060999 positive regulation of dendritic spine development(GO:0060999)
0.0 0.1 GO:0009713 catechol-containing compound biosynthetic process(GO:0009713) catecholamine biosynthetic process(GO:0042423)
0.0 0.1 GO:0046827 positive regulation of protein export from nucleus(GO:0046827)
0.0 0.1 GO:0030910 olfactory placode formation(GO:0030910) olfactory placode development(GO:0071698) olfactory placode morphogenesis(GO:0071699)
0.0 0.2 GO:0008625 extrinsic apoptotic signaling pathway via death domain receptors(GO:0008625) extrinsic apoptotic signaling pathway(GO:0097191)
0.0 0.0 GO:0042362 fat-soluble vitamin biosynthetic process(GO:0042362)
0.0 0.1 GO:0006685 sphingomyelin catabolic process(GO:0006685)
0.0 1.1 GO:0050852 T cell receptor signaling pathway(GO:0050852)
0.0 0.1 GO:0031116 positive regulation of microtubule polymerization(GO:0031116)
0.0 0.0 GO:0071514 genetic imprinting(GO:0071514)
0.0 0.1 GO:0040023 establishment of nucleus localization(GO:0040023)
0.0 0.1 GO:0015781 pyrimidine nucleotide-sugar transport(GO:0015781)
0.0 0.0 GO:0070897 RNA polymerase II transcriptional preinitiation complex assembly(GO:0051123) DNA-templated transcriptional preinitiation complex assembly(GO:0070897)
0.0 0.2 GO:0042135 neurotransmitter catabolic process(GO:0042135)
0.0 0.6 GO:0042059 negative regulation of epidermal growth factor receptor signaling pathway(GO:0042059) negative regulation of ERBB signaling pathway(GO:1901185)
0.0 0.1 GO:0060263 regulation of respiratory burst(GO:0060263)
0.0 0.0 GO:0060449 bud elongation involved in lung branching(GO:0060449)
0.0 0.0 GO:0046449 allantoin metabolic process(GO:0000255) creatinine metabolic process(GO:0046449) cellular lactam metabolic process(GO:0072338)
0.0 0.0 GO:0045085 negative regulation of interleukin-2 biosynthetic process(GO:0045085)
0.0 0.1 GO:0009405 pathogenesis(GO:0009405)
0.0 0.0 GO:0002085 inhibition of neuroepithelial cell differentiation(GO:0002085)
0.0 0.8 GO:0006968 cellular defense response(GO:0006968)
0.0 0.1 GO:0002052 positive regulation of neuroblast proliferation(GO:0002052)
0.0 0.0 GO:0048532 anatomical structure arrangement(GO:0048532)
0.0 0.1 GO:0072583 synaptic vesicle recycling(GO:0036465) synaptic vesicle endocytosis(GO:0048488) clathrin-mediated endocytosis(GO:0072583)
0.0 0.0 GO:0070634 transepithelial ammonium transport(GO:0070634)
0.0 0.1 GO:0016255 attachment of GPI anchor to protein(GO:0016255)
0.0 0.0 GO:0010939 regulation of necrotic cell death(GO:0010939)
0.0 0.3 GO:0032945 negative regulation of mononuclear cell proliferation(GO:0032945) negative regulation of lymphocyte proliferation(GO:0050672)
0.0 0.1 GO:0070493 thrombin receptor signaling pathway(GO:0070493)
0.0 0.1 GO:0050667 homocysteine metabolic process(GO:0050667)
0.0 0.0 GO:0048149 behavioral response to ethanol(GO:0048149)
0.0 0.0 GO:0010901 regulation of very-low-density lipoprotein particle remodeling(GO:0010901)
0.0 0.0 GO:0070229 negative regulation of lymphocyte apoptotic process(GO:0070229)
0.0 0.2 GO:0042531 positive regulation of tyrosine phosphorylation of STAT protein(GO:0042531)
0.0 0.0 GO:0018125 peptidyl-cysteine methylation(GO:0018125)
0.0 0.0 GO:0010985 negative regulation of lipoprotein particle clearance(GO:0010985)
0.0 0.3 GO:0018298 protein-chromophore linkage(GO:0018298)
0.0 0.0 GO:0021779 spinal cord oligodendrocyte cell differentiation(GO:0021529) spinal cord oligodendrocyte cell fate specification(GO:0021530) oligodendrocyte cell fate specification(GO:0021778) oligodendrocyte cell fate commitment(GO:0021779) glial cell fate specification(GO:0021780)
0.0 0.1 GO:0006359 regulation of transcription from RNA polymerase III promoter(GO:0006359)
0.0 0.1 GO:0007386 compartment pattern specification(GO:0007386)
0.0 0.1 GO:0060259 regulation of feeding behavior(GO:0060259)
0.0 0.1 GO:0034260 negative regulation of GTPase activity(GO:0034260)
0.0 0.1 GO:0006983 ER overload response(GO:0006983)
0.0 0.1 GO:0008608 attachment of spindle microtubules to kinetochore(GO:0008608)
0.0 0.0 GO:0060081 membrane hyperpolarization(GO:0060081)
0.0 0.2 GO:0006801 superoxide metabolic process(GO:0006801)
0.0 0.2 GO:0016578 histone deubiquitination(GO:0016578)
0.0 0.0 GO:0071503 response to heparin(GO:0071503)
0.0 0.2 GO:0006611 protein export from nucleus(GO:0006611)
0.0 0.0 GO:0010979 regulation of vitamin D 24-hydroxylase activity(GO:0010979) positive regulation of vitamin D 24-hydroxylase activity(GO:0010980)
0.0 0.1 GO:0010633 negative regulation of epithelial cell migration(GO:0010633)
0.0 0.0 GO:0001833 inner cell mass cell proliferation(GO:0001833)
0.0 0.2 GO:0003009 skeletal muscle contraction(GO:0003009)
0.0 0.2 GO:0043968 histone H2A acetylation(GO:0043968)
0.0 0.0 GO:0071542 dopaminergic neuron differentiation(GO:0071542)
0.0 0.2 GO:0030032 lamellipodium assembly(GO:0030032)
0.0 0.0 GO:0002666 T cell tolerance induction(GO:0002517) regulation of T cell tolerance induction(GO:0002664) positive regulation of T cell tolerance induction(GO:0002666)
0.0 0.1 GO:0048617 embryonic foregut morphogenesis(GO:0048617)
0.0 0.1 GO:0051044 positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
0.0 0.0 GO:0006678 glucosylceramide metabolic process(GO:0006678)
0.0 0.1 GO:0042074 cell migration involved in gastrulation(GO:0042074)
0.0 0.1 GO:0007158 neuron cell-cell adhesion(GO:0007158)
0.0 0.1 GO:0043537 negative regulation of blood vessel endothelial cell migration(GO:0043537)
0.0 0.0 GO:0000244 spliceosomal tri-snRNP complex assembly(GO:0000244)
0.0 0.1 GO:0014003 oligodendrocyte development(GO:0014003)
0.0 0.1 GO:0006273 lagging strand elongation(GO:0006273)
0.0 0.1 GO:0051546 keratinocyte migration(GO:0051546)
0.0 0.3 GO:0016236 macroautophagy(GO:0016236)
0.0 0.2 GO:0030101 natural killer cell activation(GO:0030101)
0.0 0.0 GO:0045730 respiratory burst(GO:0045730)
0.0 0.1 GO:0008653 lipopolysaccharide metabolic process(GO:0008653)
0.0 0.1 GO:0006104 succinyl-CoA metabolic process(GO:0006104)
0.0 0.1 GO:0031848 protection from non-homologous end joining at telomere(GO:0031848) telomere maintenance in response to DNA damage(GO:0043247)
0.0 0.0 GO:0010867 positive regulation of triglyceride biosynthetic process(GO:0010867)
0.0 0.1 GO:0006362 transcription elongation from RNA polymerase I promoter(GO:0006362)
0.0 0.0 GO:0002360 T cell lineage commitment(GO:0002360)
0.0 0.0 GO:0032328 alanine transport(GO:0032328)
0.0 0.0 GO:0017085 response to insecticide(GO:0017085)
0.0 0.1 GO:1904031 positive regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045737) positive regulation of cyclin-dependent protein kinase activity(GO:1904031)
0.0 0.1 GO:0031017 exocrine pancreas development(GO:0031017)
0.0 0.0 GO:0051608 histamine transport(GO:0051608)
0.0 0.0 GO:0006978 DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:0006978)
0.0 0.0 GO:0006772 thiamine metabolic process(GO:0006772)
0.0 0.0 GO:0052251 induction by organism of defense response of other organism involved in symbiotic interaction(GO:0052251)
0.0 0.1 GO:0050910 detection of mechanical stimulus involved in sensory perception of sound(GO:0050910)
0.0 0.1 GO:0050482 arachidonic acid secretion(GO:0050482) arachidonate transport(GO:1903963)
0.0 0.1 GO:0009133 nucleoside diphosphate biosynthetic process(GO:0009133)
0.0 0.1 GO:0042769 DNA damage response, detection of DNA damage(GO:0042769)
0.0 0.0 GO:0060285 cilium-dependent cell motility(GO:0060285)
0.0 0.1 GO:0032456 endocytic recycling(GO:0032456)
0.0 0.0 GO:0071360 cellular response to exogenous dsRNA(GO:0071360)
0.0 0.1 GO:0008628 hormone-mediated apoptotic signaling pathway(GO:0008628)
0.0 0.1 GO:0051205 protein insertion into membrane(GO:0051205)
0.0 0.1 GO:0003214 cardiac left ventricle morphogenesis(GO:0003214)
0.0 0.3 GO:0046320 regulation of fatty acid oxidation(GO:0046320)
0.0 0.0 GO:0051103 DNA ligation involved in DNA repair(GO:0051103)
0.0 0.0 GO:0002430 complement receptor mediated signaling pathway(GO:0002430)
0.0 0.1 GO:0000381 regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.0 0.9 GO:0060337 type I interferon signaling pathway(GO:0060337) cellular response to type I interferon(GO:0071357)
0.0 0.2 GO:0042771 intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator(GO:0042771)
0.0 0.1 GO:0009143 nucleoside triphosphate catabolic process(GO:0009143)
0.0 0.0 GO:0040009 regulation of growth rate(GO:0040009)
0.0 0.4 GO:0050772 positive regulation of axonogenesis(GO:0050772)
0.0 0.1 GO:0010739 positive regulation of protein kinase A signaling(GO:0010739)
0.0 0.2 GO:0001522 pseudouridine synthesis(GO:0001522)
0.0 0.1 GO:0006857 oligopeptide transport(GO:0006857)
0.0 0.0 GO:0019042 viral latency(GO:0019042)
0.0 0.1 GO:0032486 Rap protein signal transduction(GO:0032486)
0.0 0.0 GO:0002329 immature B cell differentiation(GO:0002327) pre-B cell differentiation(GO:0002329)
0.0 0.1 GO:0072148 epithelial cell fate commitment(GO:0072148)
0.0 0.0 GO:0007063 regulation of sister chromatid cohesion(GO:0007063)
0.0 0.1 GO:0007512 adult heart development(GO:0007512)
0.0 0.1 GO:0071168 protein localization to chromatin(GO:0071168)
0.0 0.1 GO:0008633 obsolete activation of pro-apoptotic gene products(GO:0008633)
0.0 0.0 GO:0051182 coenzyme transport(GO:0051182)
0.0 0.0 GO:0052255 modulation by symbiont of host defense response(GO:0052031) modulation by organism of defense response of other organism involved in symbiotic interaction(GO:0052255) positive regulation by symbiont of host defense response(GO:0052509) positive regulation by organism of defense response of other organism involved in symbiotic interaction(GO:0052510) modulation by organism of immune response of other organism involved in symbiotic interaction(GO:0052552) modulation by symbiont of host immune response(GO:0052553) response to immune response of other organism involved in symbiotic interaction(GO:0052564) response to host immune response(GO:0052572)
0.0 0.0 GO:0006434 seryl-tRNA aminoacylation(GO:0006434)
0.0 0.0 GO:0045416 positive regulation of interleukin-8 biosynthetic process(GO:0045416)
0.0 0.1 GO:0006361 transcription initiation from RNA polymerase I promoter(GO:0006361)
0.0 0.1 GO:0006911 phagocytosis, engulfment(GO:0006911) membrane invagination(GO:0010324)
0.0 0.1 GO:0060013 righting reflex(GO:0060013)
0.0 0.0 GO:0046185 aldehyde catabolic process(GO:0046185)
0.0 0.0 GO:0060665 regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling(GO:0060665)
0.0 0.3 GO:0000289 nuclear-transcribed mRNA poly(A) tail shortening(GO:0000289)
0.0 0.0 GO:0015816 glycine transport(GO:0015816)
0.0 0.0 GO:0010719 negative regulation of epithelial to mesenchymal transition(GO:0010719)
0.0 0.0 GO:0006907 pinocytosis(GO:0006907)
0.0 0.0 GO:0006556 S-adenosylmethionine biosynthetic process(GO:0006556)
0.0 0.2 GO:0006297 nucleotide-excision repair, DNA gap filling(GO:0006297)
0.0 0.0 GO:0006516 glycoprotein catabolic process(GO:0006516)
0.0 0.1 GO:0046689 response to mercury ion(GO:0046689)
0.0 0.1 GO:0033138 positive regulation of peptidyl-serine phosphorylation(GO:0033138)
0.0 0.2 GO:0006513 protein monoubiquitination(GO:0006513)
0.0 0.0 GO:0032733 positive regulation of interleukin-10 production(GO:0032733)
0.0 0.3 GO:0000245 spliceosomal complex assembly(GO:0000245)
0.0 0.0 GO:0032075 positive regulation of nuclease activity(GO:0032075)
0.0 0.1 GO:0060009 Sertoli cell development(GO:0060009)
0.0 0.0 GO:0071569 protein ufmylation(GO:0071569)
0.0 0.1 GO:0001867 complement activation, lectin pathway(GO:0001867)
0.0 0.0 GO:0045342 MHC class II biosynthetic process(GO:0045342)
0.0 0.0 GO:0042816 pyridoxine metabolic process(GO:0008614) pyridoxine biosynthetic process(GO:0008615) vitamin B6 metabolic process(GO:0042816) vitamin B6 biosynthetic process(GO:0042819)
0.0 0.0 GO:0090312 regulation of protein deacetylation(GO:0090311) positive regulation of protein deacetylation(GO:0090312)
0.0 0.1 GO:0031648 protein destabilization(GO:0031648)
0.0 0.2 GO:0035036 sperm-egg recognition(GO:0035036)
0.0 0.1 GO:0019673 GDP-mannose metabolic process(GO:0019673)
0.0 0.0 GO:0046952 ketone body catabolic process(GO:0046952)
0.0 0.0 GO:0042339 keratan sulfate metabolic process(GO:0042339)
0.0 0.1 GO:0016558 protein import into peroxisome matrix(GO:0016558)
0.0 0.1 GO:0045047 protein targeting to ER(GO:0045047) establishment of protein localization to endoplasmic reticulum(GO:0072599)
0.0 0.1 GO:0036296 response to increased oxygen levels(GO:0036296) response to hyperoxia(GO:0055093)
0.0 0.1 GO:0007080 mitotic metaphase plate congression(GO:0007080)
0.0 0.4 GO:0030521 androgen receptor signaling pathway(GO:0030521)
0.0 0.0 GO:0009648 photoperiodism(GO:0009648)
0.0 0.0 GO:0006106 fumarate metabolic process(GO:0006106)
0.0 0.0 GO:0051447 negative regulation of meiotic cell cycle(GO:0051447)
0.0 0.1 GO:0018106 peptidyl-histidine phosphorylation(GO:0018106)
0.0 0.2 GO:0006783 heme biosynthetic process(GO:0006783)
0.0 0.1 GO:0046627 negative regulation of insulin receptor signaling pathway(GO:0046627) negative regulation of cellular response to insulin stimulus(GO:1900077)
0.0 0.4 GO:0050434 positive regulation of viral transcription(GO:0050434)
0.0 0.2 GO:0043966 histone H3 acetylation(GO:0043966)
0.0 0.0 GO:1901419 regulation of response to alcohol(GO:1901419)
0.0 0.2 GO:0000188 inactivation of MAPK activity(GO:0000188)
0.0 0.0 GO:0072216 positive regulation of metanephros development(GO:0072216)
0.0 0.0 GO:0032717 negative regulation of interleukin-8 production(GO:0032717)
0.0 0.0 GO:0002864 hypersensitivity(GO:0002524) positive regulation of inflammatory response to antigenic stimulus(GO:0002863) regulation of acute inflammatory response to antigenic stimulus(GO:0002864) positive regulation of acute inflammatory response to antigenic stimulus(GO:0002866) regulation of hypersensitivity(GO:0002883) positive regulation of hypersensitivity(GO:0002885)
0.0 0.0 GO:0060231 mesenchymal to epithelial transition(GO:0060231)
0.0 0.1 GO:0030212 hyaluronan metabolic process(GO:0030212)
0.0 0.1 GO:0046655 folic acid metabolic process(GO:0046655)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.1 0.4 GO:0005827 polar microtubule(GO:0005827)
0.1 0.3 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
0.1 0.4 GO:0045179 apical cortex(GO:0045179)
0.1 0.3 GO:0031229 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229) nuclear membrane part(GO:0044453)
0.1 0.3 GO:0005797 Golgi medial cisterna(GO:0005797)
0.1 0.2 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)
0.1 0.3 GO:0031088 platelet dense granule membrane(GO:0031088)
0.0 0.3 GO:0044224 juxtaparanode region of axon(GO:0044224)
0.0 0.2 GO:0070695 FHF complex(GO:0070695)
0.0 0.1 GO:0042629 mast cell granule(GO:0042629)
0.0 0.5 GO:0001772 immunological synapse(GO:0001772)
0.0 0.6 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.0 0.2 GO:0071778 obsolete WINAC complex(GO:0071778)
0.0 0.2 GO:0001931 uropod(GO:0001931) cell trailing edge(GO:0031254)
0.0 0.2 GO:0005663 DNA replication factor C complex(GO:0005663)
0.0 0.5 GO:0043209 myelin sheath(GO:0043209)
0.0 0.0 GO:0071062 alphav-beta3 integrin-vitronectin complex(GO:0071062)
0.0 0.0 GO:0034363 intermediate-density lipoprotein particle(GO:0034363)
0.0 0.2 GO:0001891 phagocytic cup(GO:0001891)
0.0 0.1 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
0.0 0.1 GO:0071438 invadopodium membrane(GO:0071438)
0.0 0.1 GO:0070022 transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.0 0.1 GO:0030895 apolipoprotein B mRNA editing enzyme complex(GO:0030895)
0.0 0.1 GO:0000300 obsolete peripheral to membrane of membrane fraction(GO:0000300)
0.0 0.1 GO:0033150 cytoskeletal calyx(GO:0033150)
0.0 0.1 GO:0000796 condensin complex(GO:0000796)
0.0 0.1 GO:0008540 proteasome regulatory particle, base subcomplex(GO:0008540)
0.0 0.3 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.0 0.3 GO:0045120 pronucleus(GO:0045120)
0.0 0.2 GO:0000791 euchromatin(GO:0000791)
0.0 0.1 GO:0036454 insulin-like growth factor binding protein complex(GO:0016942) growth factor complex(GO:0036454)
0.0 0.3 GO:0030132 clathrin coat of coated pit(GO:0030132)
0.0 0.1 GO:0005750 mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
0.0 0.1 GO:0000124 SAGA complex(GO:0000124)
0.0 0.4 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.0 0.1 GO:0043657 host(GO:0018995) host cell part(GO:0033643) host intracellular part(GO:0033646) intracellular region of host(GO:0043656) host cell(GO:0043657) other organism(GO:0044215) other organism cell(GO:0044216) other organism part(GO:0044217)
0.0 0.9 GO:0030175 filopodium(GO:0030175)
0.0 0.2 GO:0032279 asymmetric synapse(GO:0032279) neuron to neuron synapse(GO:0098984)
0.0 0.1 GO:0005721 pericentric heterochromatin(GO:0005721)
0.0 0.5 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.0 0.1 GO:0070775 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.0 0.1 GO:0005896 interleukin-6 receptor complex(GO:0005896)
0.0 0.1 GO:0000445 THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.0 0.3 GO:0035631 CD40 receptor complex(GO:0035631)
0.0 0.2 GO:0032839 dendrite cytoplasm(GO:0032839)
0.0 0.1 GO:0005682 U5 snRNP(GO:0005682)
0.0 0.1 GO:0031371 ubiquitin conjugating enzyme complex(GO:0031371)
0.0 0.2 GO:0031105 septin complex(GO:0031105) septin cytoskeleton(GO:0032156)
0.0 0.1 GO:0005945 6-phosphofructokinase complex(GO:0005945)
0.0 0.2 GO:0061200 clathrin-sculpted gamma-aminobutyric acid transport vesicle(GO:0061200) clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane(GO:0061202)
0.0 0.7 GO:0005626 obsolete insoluble fraction(GO:0005626)
0.0 0.2 GO:0005861 troponin complex(GO:0005861)
0.0 0.1 GO:0031211 palmitoyltransferase complex(GO:0002178) serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211)
0.0 0.1 GO:0042627 chylomicron(GO:0042627)
0.0 0.2 GO:0016514 SWI/SNF complex(GO:0016514)
0.0 0.0 GO:0031932 TORC2 complex(GO:0031932)
0.0 0.2 GO:0008385 IkappaB kinase complex(GO:0008385)
0.0 0.2 GO:0005664 origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.0 0.2 GO:0042589 zymogen granule membrane(GO:0042589)
0.0 0.2 GO:0016585 obsolete chromatin remodeling complex(GO:0016585)
0.0 0.1 GO:0000942 condensed nuclear chromosome outer kinetochore(GO:0000942)
0.0 0.1 GO:0045334 clathrin-coated endocytic vesicle(GO:0045334)
0.0 0.1 GO:0005658 alpha DNA polymerase:primase complex(GO:0005658)
0.0 0.3 GO:0000123 histone acetyltransferase complex(GO:0000123) protein acetyltransferase complex(GO:0031248) acetyltransferase complex(GO:1902493)
0.0 0.1 GO:0034045 pre-autophagosomal structure membrane(GO:0034045)
0.0 0.2 GO:0000242 pericentriolar material(GO:0000242)
0.0 0.1 GO:0042765 GPI-anchor transamidase complex(GO:0042765)
0.0 0.1 GO:0072669 tRNA-splicing ligase complex(GO:0072669)
0.0 0.0 GO:0070552 BRISC complex(GO:0070552)
0.0 0.1 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.0 0.2 GO:0034362 low-density lipoprotein particle(GO:0034362)
0.0 0.1 GO:0042583 chromaffin granule(GO:0042583) chromaffin granule membrane(GO:0042584)
0.0 0.1 GO:0016471 vacuolar proton-transporting V-type ATPase complex(GO:0016471)
0.0 0.1 GO:0000138 Golgi trans cisterna(GO:0000138)
0.0 0.2 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)
0.0 0.7 GO:0005778 peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.0 0.2 GO:0035267 NuA4 histone acetyltransferase complex(GO:0035267)
0.0 0.0 GO:0030008 TRAPP complex(GO:0030008)
0.0 0.0 GO:0031205 endoplasmic reticulum Sec complex(GO:0031205)
0.0 0.2 GO:0030914 STAGA complex(GO:0030914)
0.0 0.1 GO:0070822 Sin3 complex(GO:0016580) Sin3-type complex(GO:0070822)
0.0 0.1 GO:0030904 retromer complex(GO:0030904)
0.0 0.0 GO:0032009 early phagosome(GO:0032009)
0.0 0.2 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.0 0.2 GO:0016235 aggresome(GO:0016235)
0.0 0.1 GO:0008290 F-actin capping protein complex(GO:0008290)
0.0 0.0 GO:0071565 nBAF complex(GO:0071565)
0.0 0.1 GO:0005697 telomerase holoenzyme complex(GO:0005697)
0.0 0.1 GO:0031080 nuclear pore outer ring(GO:0031080)
0.0 0.1 GO:0000782 telomere cap complex(GO:0000782) nuclear telomere cap complex(GO:0000783)
0.0 0.0 GO:0072379 BAT3 complex(GO:0071818) ER membrane insertion complex(GO:0072379)
0.0 0.1 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0 0.0 GO:0033553 rDNA heterochromatin(GO:0033553)
0.0 0.1 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.0 0.1 GO:0042582 primary lysosome(GO:0005766) azurophil granule(GO:0042582)
0.0 0.0 GO:0070688 MLL5-L complex(GO:0070688)
0.0 1.6 GO:0009897 external side of plasma membrane(GO:0009897)
0.0 0.0 GO:0071001 U4/U6 snRNP(GO:0071001)
0.0 2.9 GO:0005667 transcription factor complex(GO:0005667)
0.0 0.1 GO:0001741 XY body(GO:0001741)
0.0 0.0 GO:0005594 collagen type IX trimer(GO:0005594)
0.0 0.0 GO:0042825 MHC class I peptide loading complex(GO:0042824) TAP complex(GO:0042825)
0.0 0.1 GO:0070531 BRCA1-A complex(GO:0070531)
0.0 0.8 GO:0060076 excitatory synapse(GO:0060076)
0.0 0.3 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)
0.0 0.1 GO:0030126 COPI vesicle coat(GO:0030126)
0.0 0.1 GO:0072357 PTW/PP1 phosphatase complex(GO:0072357)
0.0 0.3 GO:0043204 perikaryon(GO:0043204)
0.0 0.0 GO:0090544 BAF-type complex(GO:0090544)
0.0 0.4 GO:0042645 mitochondrial nucleoid(GO:0042645)
0.0 0.5 GO:0030176 integral component of endoplasmic reticulum membrane(GO:0030176)
0.0 0.0 GO:0005787 signal peptidase complex(GO:0005787)
0.0 0.1 GO:0032589 neuron projection membrane(GO:0032589)
0.0 0.1 GO:0033179 proton-transporting V-type ATPase, V0 domain(GO:0033179)
0.0 0.2 GO:0080008 Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.0 0.1 GO:0034361 very-low-density lipoprotein particle(GO:0034361) triglyceride-rich lipoprotein particle(GO:0034385)
0.0 0.5 GO:0016605 PML body(GO:0016605)
0.0 0.1 GO:0008278 cohesin complex(GO:0008278)
0.0 0.4 GO:0099501 synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.0 0.0 GO:0030288 outer membrane-bounded periplasmic space(GO:0030288) periplasmic space(GO:0042597)
0.0 0.1 GO:0005662 DNA replication factor A complex(GO:0005662)
0.0 0.1 GO:0019908 nuclear cyclin-dependent protein kinase holoenzyme complex(GO:0019908)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.5 GO:0043522 leucine zipper domain binding(GO:0043522)
0.1 0.3 GO:0031628 opioid receptor binding(GO:0031628)
0.1 0.3 GO:0003726 double-stranded RNA adenosine deaminase activity(GO:0003726)
0.1 0.4 GO:0016004 phospholipase activator activity(GO:0016004)
0.1 0.7 GO:0030332 cyclin binding(GO:0030332)
0.1 0.3 GO:0017128 phospholipid scramblase activity(GO:0017128)
0.1 0.3 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.1 0.3 GO:0030284 estrogen receptor activity(GO:0030284)
0.1 0.2 GO:0033691 sialic acid binding(GO:0033691)
0.1 0.5 GO:0001609 G-protein coupled adenosine receptor activity(GO:0001609)
0.1 0.2 GO:0042156 obsolete zinc-mediated transcriptional activator activity(GO:0042156)
0.1 0.2 GO:0004311 farnesyltranstransferase activity(GO:0004311)
0.1 0.2 GO:0004911 interleukin-2 receptor activity(GO:0004911)
0.1 0.6 GO:0005522 profilin binding(GO:0005522)
0.1 0.2 GO:0016309 1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
0.1 0.4 GO:0016494 C-X-C chemokine receptor activity(GO:0016494)
0.1 0.2 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.1 0.8 GO:0005031 tumor necrosis factor-activated receptor activity(GO:0005031)
0.1 0.2 GO:0030368 interleukin-17 receptor activity(GO:0030368)
0.1 0.6 GO:0016493 C-C chemokine receptor activity(GO:0016493)
0.1 0.1 GO:0050510 N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity(GO:0050510)
0.1 0.2 GO:0035184 histone threonine kinase activity(GO:0035184)
0.1 0.2 GO:0004706 JUN kinase kinase kinase activity(GO:0004706)
0.1 0.3 GO:0005143 interleukin-12 receptor binding(GO:0005143)
0.1 0.1 GO:0043008 ATP-dependent protein binding(GO:0043008)
0.1 0.3 GO:0008020 G-protein coupled photoreceptor activity(GO:0008020)
0.0 0.8 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0 0.1 GO:0046975 histone methyltransferase activity (H3-K36 specific)(GO:0046975)
0.0 0.1 GO:0031014 troponin T binding(GO:0031014)
0.0 0.2 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity(GO:0004694)
0.0 0.2 GO:0052813 phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) phosphatidylinositol bisphosphate kinase activity(GO:0052813)
0.0 0.2 GO:0033170 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.0 0.1 GO:0001601 peptide YY receptor activity(GO:0001601)
0.0 0.5 GO:0099604 calcium-release channel activity(GO:0015278) ligand-gated calcium channel activity(GO:0099604)
0.0 0.4 GO:0015271 outward rectifier potassium channel activity(GO:0015271)
0.0 0.2 GO:0034452 dynactin binding(GO:0034452)
0.0 0.6 GO:0005246 calcium channel regulator activity(GO:0005246)
0.0 0.1 GO:0016748 succinyltransferase activity(GO:0016748)
0.0 0.1 GO:0030172 troponin C binding(GO:0030172)
0.0 0.1 GO:0043533 inositol 1,3,4,5 tetrakisphosphate binding(GO:0043533)
0.0 0.1 GO:0042608 T cell receptor binding(GO:0042608)
0.0 0.4 GO:0070411 I-SMAD binding(GO:0070411)
0.0 0.2 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.0 0.2 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.0 0.2 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
0.0 0.2 GO:0015379 potassium:chloride symporter activity(GO:0015379)
0.0 0.1 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454)
0.0 0.2 GO:0055103 ligase regulator activity(GO:0055103) ubiquitin-protein transferase regulator activity(GO:0055106)
0.0 0.2 GO:0001637 G-protein coupled chemoattractant receptor activity(GO:0001637) chemokine receptor activity(GO:0004950)
0.0 0.3 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0 0.6 GO:0015026 coreceptor activity(GO:0015026)
0.0 0.1 GO:0004517 nitric-oxide synthase activity(GO:0004517)
0.0 0.4 GO:0030276 clathrin binding(GO:0030276)
0.0 0.5 GO:0005095 GTPase inhibitor activity(GO:0005095)
0.0 0.3 GO:0004017 adenylate kinase activity(GO:0004017)
0.0 0.1 GO:0070653 high-density lipoprotein particle receptor binding(GO:0070653)
0.0 0.2 GO:0001727 lipid kinase activity(GO:0001727)
0.0 0.1 GO:0005432 calcium:sodium antiporter activity(GO:0005432)
0.0 0.5 GO:0004707 MAP kinase activity(GO:0004707)
0.0 0.1 GO:0047238 glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity(GO:0047238)
0.0 0.1 GO:0048018 receptor agonist activity(GO:0048018)
0.0 0.1 GO:0043024 ribosomal small subunit binding(GO:0043024)
0.0 0.2 GO:0070567 cytidylyltransferase activity(GO:0070567)
0.0 0.1 GO:0016802 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.0 0.1 GO:0010521 telomerase inhibitor activity(GO:0010521)
0.0 0.2 GO:0016308 1-phosphatidylinositol-4-phosphate 5-kinase activity(GO:0016308)
0.0 0.5 GO:0043014 alpha-tubulin binding(GO:0043014)
0.0 0.1 GO:0070548 L-glutamine aminotransferase activity(GO:0070548)
0.0 0.1 GO:0034648 histone demethylase activity (H3-K4 specific)(GO:0032453) histone demethylase activity (H3-dimethyl-K4 specific)(GO:0034648)
0.0 0.2 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.0 0.1 GO:0016907 G-protein coupled acetylcholine receptor activity(GO:0016907)
0.0 1.5 GO:0008301 DNA binding, bending(GO:0008301)
0.0 0.1 GO:0008821 crossover junction endodeoxyribonuclease activity(GO:0008821)
0.0 0.1 GO:0003829 beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity(GO:0003829)
0.0 0.2 GO:0005375 copper ion transmembrane transporter activity(GO:0005375)
0.0 0.2 GO:0015288 porin activity(GO:0015288)
0.0 0.1 GO:0042392 sphingosine-1-phosphate phosphatase activity(GO:0042392)
0.0 0.4 GO:0004889 acetylcholine-activated cation-selective channel activity(GO:0004889)
0.0 0.1 GO:0070215 obsolete MDM2 binding(GO:0070215)
0.0 0.1 GO:0043560 insulin receptor substrate binding(GO:0043560)
0.0 0.1 GO:0004095 carnitine O-palmitoyltransferase activity(GO:0004095) O-palmitoyltransferase activity(GO:0016416)
0.0 0.3 GO:0043425 bHLH transcription factor binding(GO:0043425)
0.0 0.1 GO:0003720 telomerase activity(GO:0003720) RNA-directed DNA polymerase activity(GO:0003964)
0.0 0.2 GO:0042288 MHC class I protein binding(GO:0042288)
0.0 0.1 GO:0016312 inositol bisphosphate phosphatase activity(GO:0016312)
0.0 0.1 GO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.0 0.2 GO:0070087 chromo shadow domain binding(GO:0070087)
0.0 0.0 GO:0060230 lipoprotein lipase activator activity(GO:0060230)
0.0 0.1 GO:0005113 patched binding(GO:0005113)
0.0 0.1 GO:0004974 leukotriene receptor activity(GO:0004974)
0.0 0.9 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.0 0.1 GO:0070053 thrombospondin receptor activity(GO:0070053)
0.0 0.1 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
0.0 0.1 GO:0004814 arginine-tRNA ligase activity(GO:0004814)
0.0 0.5 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.0 0.1 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
0.0 0.2 GO:0043395 heparan sulfate proteoglycan binding(GO:0043395)
0.0 0.1 GO:0003986 acetyl-CoA hydrolase activity(GO:0003986)
0.0 0.2 GO:0016888 endodeoxyribonuclease activity, producing 5'-phosphomonoesters(GO:0016888)
0.0 0.0 GO:0070492 oligosaccharide binding(GO:0070492)
0.0 0.7 GO:0016831 carboxy-lyase activity(GO:0016831)
0.0 0.0 GO:0004127 cytidylate kinase activity(GO:0004127)
0.0 0.1 GO:0070326 very-low-density lipoprotein particle receptor binding(GO:0070326)
0.0 0.0 GO:0016531 copper chaperone activity(GO:0016531)
0.0 0.1 GO:0003691 double-stranded telomeric DNA binding(GO:0003691)
0.0 0.1 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.0 0.4 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0 0.1 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624) ubiquitin-like protein conjugating enzyme binding(GO:0044390)
0.0 0.1 GO:0043175 RNA polymerase core enzyme binding(GO:0043175)
0.0 0.0 GO:0005035 death receptor activity(GO:0005035)
0.0 0.1 GO:0003872 6-phosphofructokinase activity(GO:0003872)
0.0 0.2 GO:0017025 TBP-class protein binding(GO:0017025)
0.0 0.2 GO:0051766 inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440) inositol trisphosphate kinase activity(GO:0051766)
0.0 0.1 GO:0005346 purine ribonucleotide transmembrane transporter activity(GO:0005346)
0.0 0.2 GO:0017127 cholesterol transporter activity(GO:0017127)
0.0 0.1 GO:0015333 peptide:proton symporter activity(GO:0015333) proton-dependent peptide secondary active transmembrane transporter activity(GO:0022897)
0.0 0.1 GO:0004476 mannose-6-phosphate isomerase activity(GO:0004476)
0.0 0.1 GO:0004500 dopamine beta-monooxygenase activity(GO:0004500)
0.0 0.8 GO:0061733 peptide-lysine-N-acetyltransferase activity(GO:0061733)
0.0 0.2 GO:0030371 translation repressor activity(GO:0030371)
0.0 0.2 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.0 0.1 GO:0070579 methylcytosine dioxygenase activity(GO:0070579)
0.0 0.0 GO:0031013 troponin I binding(GO:0031013)
0.0 0.1 GO:0035004 1-phosphatidylinositol-3-kinase activity(GO:0016303) phosphatidylinositol 3-kinase activity(GO:0035004)
0.0 0.1 GO:0051400 BH domain binding(GO:0051400)
0.0 0.1 GO:0005138 interleukin-6 receptor binding(GO:0005138)
0.0 0.1 GO:0001517 N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517)
0.0 0.1 GO:0000064 L-ornithine transmembrane transporter activity(GO:0000064)
0.0 0.1 GO:0004719 protein-L-isoaspartate (D-aspartate) O-methyltransferase activity(GO:0004719)
0.0 0.2 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.0 0.1 GO:0008296 3'-5'-exodeoxyribonuclease activity(GO:0008296)
0.0 0.1 GO:0019863 IgE binding(GO:0019863)
0.0 0.1 GO:0004591 oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591)
0.0 0.1 GO:0015165 pyrimidine nucleotide-sugar transmembrane transporter activity(GO:0015165)
0.0 0.1 GO:0015355 secondary active monocarboxylate transmembrane transporter activity(GO:0015355)
0.0 0.1 GO:0004301 epoxide hydrolase activity(GO:0004301)
0.0 0.1 GO:0070097 delta-catenin binding(GO:0070097)
0.0 0.1 GO:0016165 linoleate 13S-lipoxygenase activity(GO:0016165)
0.0 0.0 GO:0042289 MHC class II protein binding(GO:0042289)
0.0 0.1 GO:0004775 succinate-CoA ligase (ADP-forming) activity(GO:0004775)
0.0 0.0 GO:0043398 HLH domain binding(GO:0043398)
0.0 0.7 GO:0003899 DNA-directed RNA polymerase activity(GO:0003899) RNA polymerase activity(GO:0034062)
0.0 0.1 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.0 0.2 GO:0004579 dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.0 0.3 GO:0005001 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.0 0.1 GO:0008131 primary amine oxidase activity(GO:0008131)
0.0 0.1 GO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.0 0.1 GO:0008321 Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.0 0.1 GO:0003923 GPI-anchor transamidase activity(GO:0003923)
0.0 0.1 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.0 0.1 GO:0004704 NF-kappaB-inducing kinase activity(GO:0004704)
0.0 0.2 GO:0046965 retinoid X receptor binding(GO:0046965)
0.0 0.1 GO:0042808 obsolete neuronal Cdc2-like kinase binding(GO:0042808)
0.0 0.1 GO:0009881 photoreceptor activity(GO:0009881)
0.0 0.1 GO:0017162 aryl hydrocarbon receptor binding(GO:0017162)
0.0 0.2 GO:0004697 protein kinase C activity(GO:0004697)
0.0 0.1 GO:0008332 low voltage-gated calcium channel activity(GO:0008332)
0.0 0.1 GO:0008889 glycerophosphodiester phosphodiesterase activity(GO:0008889)
0.0 0.1 GO:0008195 phosphatidate phosphatase activity(GO:0008195)
0.0 0.1 GO:0004459 L-lactate dehydrogenase activity(GO:0004459)
0.0 0.2 GO:0035251 UDP-glucosyltransferase activity(GO:0035251)
0.0 0.1 GO:0033613 activating transcription factor binding(GO:0033613)
0.0 0.0 GO:0048256 flap endonuclease activity(GO:0048256)
0.0 0.1 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.0 0.0 GO:0004505 phenylalanine 4-monooxygenase activity(GO:0004505)
0.0 0.2 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.0 0.0 GO:0031849 olfactory receptor binding(GO:0031849)
0.0 0.1 GO:0008649 rRNA methyltransferase activity(GO:0008649)
0.0 0.0 GO:0015464 acetylcholine receptor activity(GO:0015464)
0.0 0.0 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.0 0.0 GO:0004774 succinate-CoA ligase activity(GO:0004774)
0.0 0.2 GO:0005487 nucleocytoplasmic transporter activity(GO:0005487)
0.0 0.0 GO:0016895 exodeoxyribonuclease activity(GO:0004529) exodeoxyribonuclease activity, producing 5'-phosphomonoesters(GO:0016895)
0.0 0.1 GO:0004663 Rab geranylgeranyltransferase activity(GO:0004663)
0.0 0.1 GO:0004972 NMDA glutamate receptor activity(GO:0004972)
0.0 0.0 GO:0008035 high-density lipoprotein particle binding(GO:0008035)
0.0 0.1 GO:0015347 sodium-independent organic anion transmembrane transporter activity(GO:0015347)
0.0 0.1 GO:0016565 obsolete general transcriptional repressor activity(GO:0016565)
0.0 0.0 GO:0003985 acetyl-CoA C-acetyltransferase activity(GO:0003985)
0.0 0.0 GO:0098599 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.0 0.0 GO:0030899 calcium-dependent ATPase activity(GO:0030899)
0.0 0.1 GO:0008429 phosphatidylethanolamine binding(GO:0008429)
0.0 0.1 GO:0030274 LIM domain binding(GO:0030274)
0.0 0.2 GO:0003711 obsolete transcription elongation regulator activity(GO:0003711)
0.0 0.1 GO:0001671 ATPase activator activity(GO:0001671)
0.0 0.0 GO:0004477 methenyltetrahydrofolate cyclohydrolase activity(GO:0004477)
0.0 0.1 GO:0050750 low-density lipoprotein particle receptor binding(GO:0050750)
0.0 0.1 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.0 0.1 GO:0004331 fructose-2,6-bisphosphate 2-phosphatase activity(GO:0004331)
0.0 0.0 GO:0043141 ATP-dependent 5'-3' DNA helicase activity(GO:0043141)
0.0 0.2 GO:0001540 beta-amyloid binding(GO:0001540)
0.0 0.2 GO:0048365 Rac GTPase binding(GO:0048365)
0.0 0.1 GO:0015924 mannosyl-oligosaccharide mannosidase activity(GO:0015924)
0.0 0.0 GO:0017060 3-galactosyl-N-acetylglucosaminide 4-alpha-L-fucosyltransferase activity(GO:0017060)
0.0 0.1 GO:0016857 racemase and epimerase activity, acting on carbohydrates and derivatives(GO:0016857)
0.0 0.0 GO:0015211 purine nucleoside transmembrane transporter activity(GO:0015211)
0.0 0.1 GO:0031781 melanocortin receptor binding(GO:0031779) type 3 melanocortin receptor binding(GO:0031781) type 4 melanocortin receptor binding(GO:0031782)
0.0 0.0 GO:0003706 obsolete ligand-regulated transcription factor activity(GO:0003706)
0.0 0.0 GO:0004875 complement receptor activity(GO:0004875)
0.0 0.5 GO:0098531 RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding(GO:0004879) transcription factor activity, direct ligand regulated sequence-specific DNA binding(GO:0098531)
0.0 0.0 GO:0003910 DNA ligase activity(GO:0003909) DNA ligase (ATP) activity(GO:0003910)
0.0 0.1 GO:0004596 peptide alpha-N-acetyltransferase activity(GO:0004596)
0.0 0.2 GO:0042809 vitamin D receptor binding(GO:0042809)
0.0 0.1 GO:0070410 co-SMAD binding(GO:0070410)
0.0 0.0 GO:0030343 vitamin D3 25-hydroxylase activity(GO:0030343) vitamin D 25-hydroxylase activity(GO:0070643)
0.0 0.1 GO:0016208 AMP binding(GO:0016208)
0.0 0.1 GO:0015057 thrombin receptor activity(GO:0015057)
0.0 0.1 GO:0046625 sphingolipid binding(GO:0046625)
0.0 0.2 GO:0000175 3'-5'-exoribonuclease activity(GO:0000175)
0.0 0.0 GO:0034237 protein kinase A regulatory subunit binding(GO:0034237)
0.0 0.1 GO:0046974 histone methyltransferase activity (H3-K9 specific)(GO:0046974)
0.0 0.1 GO:0017040 ceramidase activity(GO:0017040)
0.0 0.1 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.0 0.0 GO:0034236 protein kinase A catalytic subunit binding(GO:0034236)
0.0 0.1 GO:0004616 phosphogluconate dehydrogenase (decarboxylating) activity(GO:0004616)
0.0 0.1 GO:0030159 receptor signaling complex scaffold activity(GO:0030159)
0.0 0.4 GO:0008094 DNA-dependent ATPase activity(GO:0008094)
0.0 0.0 GO:0015349 thyroid hormone transmembrane transporter activity(GO:0015349)
0.0 0.1 GO:0008353 RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.0 0.5 GO:0003678 DNA helicase activity(GO:0003678)
0.0 0.1 GO:0004000 adenosine deaminase activity(GO:0004000)
0.0 0.1 GO:0034593 phosphatidylinositol bisphosphate phosphatase activity(GO:0034593)
0.0 0.1 GO:0030346 protein phosphatase 2B binding(GO:0030346)
0.0 0.0 GO:0030976 thiamine pyrophosphate binding(GO:0030976)
0.0 0.0 GO:0001591 dopamine neurotransmitter receptor activity, coupled via Gi/Go(GO:0001591)
0.0 0.0 GO:0003831 beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity(GO:0003831)
0.0 0.2 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.0 0.2 GO:0016638 oxidoreductase activity, acting on the CH-NH2 group of donors(GO:0016638)
0.0 0.0 GO:0004828 serine-tRNA ligase activity(GO:0004828)
0.0 1.2 GO:0017124 SH3 domain binding(GO:0017124)
0.0 0.0 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.0 0.0 GO:0005092 GDP-dissociation inhibitor activity(GO:0005092)
0.0 0.2 GO:0003995 acyl-CoA dehydrogenase activity(GO:0003995)
0.0 0.1 GO:0003688 DNA replication origin binding(GO:0003688)
0.0 0.1 GO:0005159 insulin-like growth factor receptor binding(GO:0005159)
0.0 0.1 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.0 0.1 GO:0043548 phosphatidylinositol 3-kinase binding(GO:0043548)
0.0 0.1 GO:0005007 fibroblast growth factor-activated receptor activity(GO:0005007)
0.0 0.1 GO:0015643 toxic substance binding(GO:0015643)
0.0 0.0 GO:0008327 methyl-CpG binding(GO:0008327)
0.0 1.2 GO:0003702 obsolete RNA polymerase II transcription factor activity(GO:0003702)
0.0 0.2 GO:0005248 voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
0.0 0.0 GO:0099528 G-protein coupled neurotransmitter receptor activity(GO:0099528)
0.0 0.0 GO:0016160 alpha-amylase activity(GO:0004556) amylase activity(GO:0016160)
0.0 0.0 GO:0004339 glucan 1,4-alpha-glucosidase activity(GO:0004339)
0.0 0.0 GO:0070412 R-SMAD binding(GO:0070412)
0.0 0.0 GO:0019238 cyclohydrolase activity(GO:0019238)
0.0 0.1 GO:0003840 gamma-glutamyltransferase activity(GO:0003840)
0.0 0.0 GO:0034187 obsolete apolipoprotein E binding(GO:0034187)
0.0 0.1 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.0 0.2 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.0 0.0 GO:0035241 protein-arginine omega-N monomethyltransferase activity(GO:0035241)
0.0 0.0 GO:0015168 glycerol transmembrane transporter activity(GO:0015168)
0.0 0.1 GO:0016846 carbon-sulfur lyase activity(GO:0016846)
0.0 0.1 GO:0050811 GABA receptor binding(GO:0050811)
0.0 0.1 GO:0008408 3'-5' exonuclease activity(GO:0008408)
0.0 0.0 GO:0004957 prostaglandin E receptor activity(GO:0004957)
0.0 0.0 GO:0045569 TRAIL binding(GO:0045569)
0.0 0.0 GO:0015184 L-cystine transmembrane transporter activity(GO:0015184)
0.0 0.1 GO:0004994 somatostatin receptor activity(GO:0004994)
0.0 0.0 GO:0004465 lipoprotein lipase activity(GO:0004465)
0.0 0.1 GO:0015385 sodium:proton antiporter activity(GO:0015385)
0.0 0.1 GO:0055056 D-glucose transmembrane transporter activity(GO:0055056)
0.0 0.0 GO:0061731 ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.1 PID PI3KCI AKT PATHWAY Class I PI3K signaling events mediated by Akt
0.1 1.8 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4
0.1 0.9 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0 1.4 PID EPHRINB REV PATHWAY Ephrin B reverse signaling
0.0 0.7 SA PTEN PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.0 0.3 ST IL 13 PATHWAY Interleukin 13 (IL-13) Pathway
0.0 0.7 PID FAS PATHWAY FAS (CD95) signaling pathway
0.0 0.3 PID BETA CATENIN DEG PATHWAY Degradation of beta catenin
0.0 1.5 PID CD8 TCR PATHWAY TCR signaling in naïve CD8+ T cells
0.0 0.8 PID WNT CANONICAL PATHWAY Canonical Wnt signaling pathway
0.0 0.1 PID TCR RAS PATHWAY Ras signaling in the CD4+ TCR pathway
0.0 0.3 SA FAS SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.0 0.9 PID ERBB1 INTERNALIZATION PATHWAY Internalization of ErbB1
0.0 1.0 PID PI3KCI PATHWAY Class I PI3K signaling events
0.0 0.0 PID ARF6 DOWNSTREAM PATHWAY Arf6 downstream pathway
0.0 0.0 PID CXCR3 PATHWAY CXCR3-mediated signaling events
0.0 0.4 PID IL27 PATHWAY IL27-mediated signaling events
0.0 0.3 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.0 0.1 ST STAT3 PATHWAY STAT3 Pathway
0.0 0.7 SIG INSULIN RECEPTOR PATHWAY IN CARDIAC MYOCYTES Genes related to the insulin receptor pathway
0.0 1.2 PID IL4 2PATHWAY IL4-mediated signaling events
0.0 0.6 PID MYC PATHWAY C-MYC pathway
0.0 0.1 PID IL2 PI3K PATHWAY IL2 signaling events mediated by PI3K
0.0 0.3 PID THROMBIN PAR4 PATHWAY PAR4-mediated thrombin signaling events
0.0 0.6 PID NFAT 3PATHWAY Role of Calcineurin-dependent NFAT signaling in lymphocytes
0.0 0.4 PID IL12 2PATHWAY IL12-mediated signaling events
0.0 0.2 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.0 0.2 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.0 0.7 PID ECADHERIN STABILIZATION PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.0 0.3 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.0 0.2 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.0 0.1 PID CXCR4 PATHWAY CXCR4-mediated signaling events
0.0 0.4 PID FCER1 PATHWAY Fc-epsilon receptor I signaling in mast cells
0.0 0.1 ST TYPE I INTERFERON PATHWAY Type I Interferon (alpha/beta IFN) Pathway
0.0 0.3 PID REELIN PATHWAY Reelin signaling pathway
0.0 0.1 SIG BCR SIGNALING PATHWAY Members of the BCR signaling pathway
0.0 1.1 PID SMAD2 3NUCLEAR PATHWAY Regulation of nuclear SMAD2/3 signaling
0.0 0.1 ST PAC1 RECEPTOR PATHWAY PAC1 Receptor Pathway
0.0 0.0 PID S1P S1P1 PATHWAY S1P1 pathway
0.0 0.1 PID THROMBIN PAR1 PATHWAY PAR1-mediated thrombin signaling events
0.0 0.2 SIG PIP3 SIGNALING IN B LYMPHOCYTES Genes related to PIP3 signaling in B lymphocytes
0.0 0.2 PID ARF6 PATHWAY Arf6 signaling events
0.0 0.2 PID ERBB2 ERBB3 PATHWAY ErbB2/ErbB3 signaling events
0.0 0.6 PID TELOMERASE PATHWAY Regulation of Telomerase
0.0 0.4 PID TNF PATHWAY TNF receptor signaling pathway
0.0 0.6 PID BETA CATENIN NUC PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription
0.0 0.0 PID SYNDECAN 1 PATHWAY Syndecan-1-mediated signaling events
0.0 0.4 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.0 0.1 PID TCR PATHWAY TCR signaling in naïve CD4+ T cells
0.0 0.1 PID TRAIL PATHWAY TRAIL signaling pathway
0.0 0.6 PID FANCONI PATHWAY Fanconi anemia pathway
0.0 0.2 SIG CD40PATHWAYMAP Genes related to CD40 signaling
0.0 0.2 ST MYOCYTE AD PATHWAY Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.0 0.2 PID ER NONGENOMIC PATHWAY Plasma membrane estrogen receptor signaling
0.0 0.2 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0 0.1 PID P38 ALPHA BETA PATHWAY Regulation of p38-alpha and p38-beta
0.0 0.0 PID S1P S1P4 PATHWAY S1P4 pathway
0.0 0.0 PID IL5 PATHWAY IL5-mediated signaling events
0.0 0.1 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0 0.1 PID ATF2 PATHWAY ATF-2 transcription factor network
0.0 0.4 PID AR TF PATHWAY Regulation of Androgen receptor activity
0.0 0.3 PID TGFBR PATHWAY TGF-beta receptor signaling
0.0 0.2 PID HES HEY PATHWAY Notch-mediated HES/HEY network
0.0 0.1 PID BCR 5PATHWAY BCR signaling pathway
0.0 0.2 PID HEDGEHOG GLI PATHWAY Hedgehog signaling events mediated by Gli proteins
0.0 0.2 PID CD8 TCR DOWNSTREAM PATHWAY Downstream signaling in naïve CD8+ T cells

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.2 REACTOME CD28 DEPENDENT VAV1 PATHWAY Genes involved in CD28 dependent Vav1 pathway
0.1 0.3 REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.1 0.1 REACTOME REGULATION OF INSULIN SECRETION Genes involved in Regulation of Insulin Secretion
0.1 0.1 REACTOME DOWNSTREAM TCR SIGNALING Genes involved in Downstream TCR signaling
0.1 0.6 REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.1 0.2 REACTOME BINDING AND ENTRY OF HIV VIRION Genes involved in Binding and entry of HIV virion
0.0 1.2 REACTOME IL RECEPTOR SHC SIGNALING Genes involved in Interleukin receptor SHC signaling
0.0 0.6 REACTOME P38MAPK EVENTS Genes involved in p38MAPK events
0.0 0.4 REACTOME ROLE OF DCC IN REGULATING APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.0 0.9 REACTOME GENERATION OF SECOND MESSENGER MOLECULES Genes involved in Generation of second messenger molecules
0.0 0.9 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.0 0.2 REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX UPON TLR7 8 OR 9 STIMULATION Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
0.0 0.7 REACTOME N GLYCAN ANTENNAE ELONGATION IN THE MEDIAL TRANS GOLGI Genes involved in N-glycan antennae elongation in the medial/trans-Golgi
0.0 0.0 REACTOME AUTODEGRADATION OF THE E3 UBIQUITIN LIGASE COP1 Genes involved in Autodegradation of the E3 ubiquitin ligase COP1
0.0 0.6 REACTOME RNA POL III CHAIN ELONGATION Genes involved in RNA Polymerase III Chain Elongation
0.0 0.1 REACTOME ENDOSOMAL VACUOLAR PATHWAY Genes involved in Endosomal/Vacuolar pathway
0.0 0.8 REACTOME RORA ACTIVATES CIRCADIAN EXPRESSION Genes involved in RORA Activates Circadian Expression
0.0 0.3 REACTOME GAP JUNCTION DEGRADATION Genes involved in Gap junction degradation
0.0 0.3 REACTOME SEMA3A PAK DEPENDENT AXON REPULSION Genes involved in Sema3A PAK dependent Axon repulsion
0.0 0.8 REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE Genes involved in Synthesis of PIPs at the plasma membrane
0.0 0.7 REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING Genes involved in Downregulation of TGF-beta receptor signaling
0.0 0.4 REACTOME HIGHLY CALCIUM PERMEABLE POSTSYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Highly calcium permeable postsynaptic nicotinic acetylcholine receptors
0.0 0.2 REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.0 0.6 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.0 0.3 REACTOME RAS ACTIVATION UOPN CA2 INFUX THROUGH NMDA RECEPTOR Genes involved in Ras activation uopn Ca2+ infux through NMDA receptor
0.0 0.1 REACTOME CTLA4 INHIBITORY SIGNALING Genes involved in CTLA4 inhibitory signaling
0.0 0.3 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.0 0.2 REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 3 PROMOTER Genes involved in RNA Polymerase III Transcription Initiation From Type 3 Promoter
0.0 0.0 REACTOME DESTABILIZATION OF MRNA BY KSRP Genes involved in Destabilization of mRNA by KSRP
0.0 0.5 REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.0 0.4 REACTOME CTNNB1 PHOSPHORYLATION CASCADE Genes involved in Beta-catenin phosphorylation cascade
0.0 0.4 REACTOME REGULATORY RNA PATHWAYS Genes involved in Regulatory RNA pathways
0.0 0.3 REACTOME ALPHA LINOLENIC ACID ALA METABOLISM Genes involved in alpha-linolenic acid (ALA) metabolism
0.0 0.8 REACTOME GLYCOSPHINGOLIPID METABOLISM Genes involved in Glycosphingolipid metabolism
0.0 0.1 REACTOME TGF BETA RECEPTOR SIGNALING ACTIVATES SMADS Genes involved in TGF-beta receptor signaling activates SMADs
0.0 0.1 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.0 0.2 REACTOME COPI MEDIATED TRANSPORT Genes involved in COPI Mediated Transport
0.0 0.6 REACTOME TRANSPORT OF RIBONUCLEOPROTEINS INTO THE HOST NUCLEUS Genes involved in Transport of Ribonucleoproteins into the Host Nucleus
0.0 0.2 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins
0.0 0.5 REACTOME EXTENSION OF TELOMERES Genes involved in Extension of Telomeres
0.0 0.4 REACTOME NOD1 2 SIGNALING PATHWAY Genes involved in NOD1/2 Signaling Pathway
0.0 0.3 REACTOME FANCONI ANEMIA PATHWAY Genes involved in Fanconi Anemia pathway
0.0 0.1 REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.0 0.1 REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.0 0.5 REACTOME REGULATION OF BETA CELL DEVELOPMENT Genes involved in Regulation of beta-cell development
0.0 0.1 REACTOME DSCAM INTERACTIONS Genes involved in DSCAM interactions
0.0 0.1 REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.0 0.1 REACTOME INTEGRATION OF PROVIRUS Genes involved in Integration of provirus
0.0 0.1 REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS Genes involved in Membrane binding and targetting of GAG proteins
0.0 0.3 REACTOME RNA POL I TRANSCRIPTION INITIATION Genes involved in RNA Polymerase I Transcription Initiation
0.0 0.0 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.0 0.3 REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.0 0.4 REACTOME G1 PHASE Genes involved in G1 Phase
0.0 0.9 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.0 0.2 REACTOME NUCLEOTIDE LIKE PURINERGIC RECEPTORS Genes involved in Nucleotide-like (purinergic) receptors
0.0 0.3 REACTOME LYSOSOME VESICLE BIOGENESIS Genes involved in Lysosome Vesicle Biogenesis
0.0 0.3 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.0 0.3 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.0 0.0 REACTOME RNA POL I PROMOTER OPENING Genes involved in RNA Polymerase I Promoter Opening
0.0 0.0 REACTOME INTERACTIONS OF VPR WITH HOST CELLULAR PROTEINS Genes involved in Interactions of Vpr with host cellular proteins
0.0 0.0 REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION Genes involved in activated TAK1 mediates p38 MAPK activation
0.0 0.9 REACTOME P75 NTR RECEPTOR MEDIATED SIGNALLING Genes involved in p75 NTR receptor-mediated signalling
0.0 0.0 REACTOME TRAF3 DEPENDENT IRF ACTIVATION PATHWAY Genes involved in TRAF3-dependent IRF activation pathway
0.0 0.2 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.0 0.0 REACTOME SHC MEDIATED SIGNALLING Genes involved in SHC-mediated signalling
0.0 0.1 REACTOME RETROGRADE NEUROTROPHIN SIGNALLING Genes involved in Retrograde neurotrophin signalling
0.0 0.2 REACTOME TRANSPORT TO THE GOLGI AND SUBSEQUENT MODIFICATION Genes involved in Transport to the Golgi and subsequent modification
0.0 0.7 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.0 0.1 REACTOME ARMS MEDIATED ACTIVATION Genes involved in ARMS-mediated activation
0.0 0.2 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.0 0.6 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0 0.1 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.0 0.0 REACTOME IRAK1 RECRUITS IKK COMPLEX Genes involved in IRAK1 recruits IKK complex
0.0 0.1 REACTOME ASSOCIATION OF LICENSING FACTORS WITH THE PRE REPLICATIVE COMPLEX Genes involved in Association of licensing factors with the pre-replicative complex
0.0 0.2 REACTOME SYNTHESIS OF PC Genes involved in Synthesis of PC
0.0 0.0 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
0.0 0.4 REACTOME MRNA SPLICING MINOR PATHWAY Genes involved in mRNA Splicing - Minor Pathway
0.0 0.0 REACTOME DESTABILIZATION OF MRNA BY AUF1 HNRNP D0 Genes involved in Destabilization of mRNA by AUF1 (hnRNP D0)
0.0 0.2 REACTOME ACYL CHAIN REMODELLING OF PS Genes involved in Acyl chain remodelling of PS
0.0 0.2 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.0 0.1 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.0 0.0 REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING Genes involved in Advanced glycosylation endproduct receptor signaling
0.0 0.2 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.0 0.0 REACTOME TRANSPORT OF MATURE MRNA DERIVED FROM AN INTRONLESS TRANSCRIPT Genes involved in Transport of Mature mRNA Derived from an Intronless Transcript
0.0 0.2 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.0 0.0 REACTOME PRE NOTCH TRANSCRIPTION AND TRANSLATION Genes involved in Pre-NOTCH Transcription and Translation
0.0 0.1 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.0 0.0 REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR Genes involved in Trafficking and processing of endosomal TLR
0.0 0.4 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 0.1 REACTOME DOUBLE STRAND BREAK REPAIR Genes involved in Double-Strand Break Repair
0.0 0.1 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
0.0 0.1 REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha