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ENCODE: H3K4me1 ChIP-Seq of primary human cells

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Results for PROX1

Z-value: 1.94

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Transcription factors associated with PROX1

Gene Symbol	Gene ID	Gene Info
PROX1 Ensembl NCBI GeneCards UniProt	ENSG00000117707.11	prospero homeobox 1

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE	Gene	Distance	Association probability	Pearson corr. coef.	P-value	Plot
chr1_214157098_214157249	PROX1	649	0.713974	0.74	2.3e-02	Click!
chr1_214156856_214157007	PROX1	407	0.852454	0.55	1.3e-01	Click!
chr1_214162177_214162368	PROX1	412	0.794175	0.51	1.6e-01	Click!
chr1_214161309_214161479	PROX1	108	0.835063	0.50	1.7e-01	Click!
chr1_214161610_214162106	PROX1	2	0.955882	0.48	1.9e-01	Click!

Activity of the PROX1 motif across conditions

Conditions sorted by the z-value of the PROX1 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE)	Target Score	Top associated gene	Gene Info	Distance of CRE to TSS	CRE/Gene association probability
chr1_25320280_25320441	0.91	RUNX3	runt-related transcription factor 3	28859	0.16
chr16_19728567_19728792	0.84	KNOP1	lysine-rich nucleolar protein 1	774	0.42
chr11_326229_326864	0.77	IFITM3	interferon induced transmembrane protein 3	991	0.28
chr11_114086673_114087539	0.77	NNMT	nicotinamide N-methyltransferase	41447	0.17
chr11_46352086_46352730	0.77	DGKZ	diacylglycerol kinase, zeta	2047	0.27
chr2_234329351_234329502	0.75	DGKD	diacylglycerol kinase, delta 130kDa	32626	0.14
chr14_22997541_22997805	0.71	TRAJ15	T cell receptor alpha joining 15	907	0.43
chr7_150324697_150324953	0.71	GIMAP6	GTPase, IMAP family member 6	4609	0.22
chr9_116283314_116283465	0.71	RGS3	regulator of G-protein signaling 3	3839	0.27
chr16_79303009_79303465	0.69	ENSG00000222244	.	4886	0.33
chr6_36077167_36077664	0.69	MAPK13	mitogen-activated protein kinase 13	20683	0.16
chr6_112126149_112126486	0.69	FYN	FYN oncogene related to SRC, FGR, YES	6691	0.3
chr8_128990046_128990302	0.67	ENSG00000221771	.	17295	0.16
chr18_13380419_13380663	0.67	LDLRAD4	low density lipoprotein receptor class A domain containing 4	2012	0.28
chr16_53551479_53551692	0.66	AKTIP	AKT interacting protein	13262	0.21
chr3_128480143_128480294	0.66	ENSG00000244232	.	23772	0.16
chr14_52368182_52368373	0.65	GNG2	guanine nucleotide binding protein (G protein), gamma 2	11553	0.17
chr11_128481294_128481657	0.65	ETS1	v-ets avian erythroblastosis virus E26 oncogene homolog 1	24022	0.2
chr10_5332260_5332573	0.64	AKR1C7P	aldo-keto reductase family 1, member C7, pseudogene	1983	0.35
chr4_40309280_40309495	0.63	CHRNA9	cholinergic receptor, nicotinic, alpha 9 (neuronal)	27959	0.19
chr10_11254490_11254686	0.61	RP3-323N1.2		41249	0.16
chr15_93357238_93357416	0.61	FAM174B	family with sequence similarity 174, member B	4299	0.19
chr3_15370184_15370338	0.61	SH3BP5	SH3-domain binding protein 5 (BTK-associated)	3806	0.17
chr7_50187399_50187568	0.61	AC020743.2		5064	0.25
chr2_25559592_25559774	0.60	DNMT3A	DNA (cytosine-5-)-methyltransferase 3 alpha	5071	0.23
chr14_99705171_99705454	0.59	AL109767.1		23973	0.19
chr7_157166465_157166616	0.58	DNAJB6	DnaJ (Hsp40) homolog, subfamily B, member 6	34025	0.19
chr12_11002723_11002874	0.58	PRR4	proline rich 4 (lacrimal)	724	0.56
chr9_378046_378197	0.58	DOCK8	dedicator of cytokinesis 8	11870	0.22
chr12_96770717_96770905	0.58	CDK17	cyclin-dependent kinase 17	22331	0.18
chr10_11183961_11184120	0.56	CELF2	CUGBP, Elav-like family member 2	22953	0.18
chr16_1609129_1609769	0.56	LA16c-425C2.1		20860	0.08
chr9_92032968_92033239	0.56	SEMA4D	sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D	645	0.78
chr13_41207953_41208104	0.55	FOXO1	forkhead box O1	32706	0.19
chr2_74401509_74401660	0.55	MOB1A	MOB kinase activator 1A	1640	0.27
chr14_61902078_61902229	0.54	PRKCH	protein kinase C, eta	7123	0.26
chr2_29223353_29223504	0.54	FAM179A	family with sequence similarity 179, member A	17699	0.14
chr9_123467524_123467712	0.54	MEGF9	multiple EGF-like-domains 9	8994	0.26
chr1_25249924_25250075	0.54	RUNX3	runt-related transcription factor 3	5613	0.25
chr2_97579532_97579773	0.54	FAM178B	family with sequence similarity 178, member B	15782	0.14
chr9_36478011_36478162	0.53	RNF38	ring finger protein 38	76891	0.1
chr1_20511735_20512008	0.53	UBXN10	UBX domain protein 10	707	0.5
chr3_56952065_56952464	0.53	ARHGEF3	Rho guanine nucleotide exchange factor (GEF) 3	1765	0.42
chr1_101594560_101594920	0.52	ENSG00000252765	.	3969	0.25
chr12_107141176_107141327	0.52	RP11-482D24.3		14407	0.17
chr11_118801744_118801895	0.52	ENSG00000239726	.	101	0.92
chr20_5573948_5574171	0.52	GPCPD1	glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae)	17613	0.24
chr12_21766078_21766229	0.52	GYS2	glycogen synthase 2 (liver)	8372	0.2
chr8_129595182_129595552	0.52	ENSG00000221351	.	236673	0.02
chr17_7397267_7397418	0.52	POLR2A	polymerase (RNA) II (DNA directed) polypeptide A, 220kDa	9403	0.06
chr20_43609081_43609330	0.52	STK4	serine/threonine kinase 4	14038	0.14
chr1_231747664_231747892	0.52	LINC00582	long intergenic non-protein coding RNA 582	58	0.98
chr14_97924480_97924631	0.52	ENSG00000240730	.	71955	0.14
chr4_40303302_40303674	0.51	CHRNA9	cholinergic receptor, nicotinic, alpha 9 (neuronal)	33858	0.17
chr9_117668023_117668209	0.51	TNFSF8	tumor necrosis factor (ligand) superfamily, member 8	24581	0.23
chr15_91116536_91116733	0.51	CRTC3	CREB regulated transcription coactivator 3	20311	0.15
chr3_58100941_58101092	0.51	FLNB	filamin B, beta	34577	0.17
chr18_60955745_60955940	0.51	RP11-28F1.2		25473	0.16
chr21_40347343_40347494	0.51	ENSG00000272015	.	80709	0.1
chr11_6769233_6769567	0.51	OR2AG2	olfactory receptor, family 2, subfamily AG, member 2	20886	0.11
chr12_65025633_65025886	0.51	RP11-338E21.2		3635	0.16
chr1_77746575_77746817	0.51	AK5	adenylate kinase 5	1040	0.61
chr12_121530141_121530589	0.51	ENSG00000201945	.	14481	0.16
chr1_42382630_42382984	0.51	HIVEP3	human immunodeficiency virus type I enhancer binding protein 3	1362	0.59
chrX_147391495_147391734	0.51	AC002368.4		190521	0.03
chr7_150183670_150183944	0.50	GIMAP7	GTPase, IMAP family member 7	28111	0.14
chr11_68233185_68233560	0.50	PPP6R3	protein phosphatase 6, regulatory subunit 3	5091	0.2
chr11_73729911_73730186	0.50	UCP3	uncoupling protein 3 (mitochondrial, proton carrier)	9568	0.16
chr14_64204068_64204219	0.50	ENSG00000252749	.	981	0.54
chr1_112045793_112046152	0.50	ADORA3	adenosine A3 receptor	138	0.93
chr16_3510818_3510980	0.50	NAA60	N(alpha)-acetyltransferase 60, NatF catalytic subunit	2769	0.18
chr2_136887722_136888188	0.49	CXCR4	chemokine (C-X-C motif) receptor 4	12220	0.28
chr7_50429911_50430494	0.49	IKZF1	IKAROS family zinc finger 1 (Ikaros)	62957	0.12
chr4_122113271_122113718	0.49	ENSG00000252183	.	564	0.8
chr15_44964229_44964380	0.49	PATL2	protein associated with topoisomerase II homolog 2 (yeast)	3621	0.18
chrX_44821643_44821794	0.49	ENSG00000252113	.	76967	0.1
chr7_142045451_142045602	0.48	PRSS3P3	protease, serine, 3 pseudogene 3	55917	0.14
chr6_1537339_1537490	0.48	ENSG00000243439	.	29857	0.22
chr16_12103610_12103841	0.48	RP11-166B2.7		32018	0.1
chr1_33337573_33337724	0.48	FNDC5	fibronectin type III domain containing 5	433	0.77
chr20_31557233_31557384	0.47	EFCAB8	EF-hand calcium binding domain 8	9657	0.16
chr19_16480711_16480862	0.47	EPS15L1	epidermal growth factor receptor pathway substrate 15-like 1	8022	0.15
chrX_19761612_19761864	0.47	SH3KBP1	SH3-domain kinase binding protein 1	2783	0.4
chr4_109081453_109081912	0.47	LEF1	lymphoid enhancer-binding factor 1	5775	0.24
chr14_65237977_65238128	0.47	SPTB	spectrin, beta, erythrocytic	11216	0.2
chr19_3970402_3970671	0.47	DAPK3	death-associated protein kinase 3	86	0.94
chr12_120512187_120512338	0.47	CCDC64	coiled-coil domain containing 64	2755	0.23
chr13_24841056_24841207	0.47	SPATA13	spermatogenesis associated 13	3695	0.21
chr12_42737573_42737724	0.47	PPHLN1	periphilin 1	42	0.97
chr5_145589313_145589581	0.47	RBM27	RNA binding motif protein 27	6284	0.21
chr8_2092796_2092947	0.47	MYOM2	myomesin 2	99687	0.08
chr3_71508207_71508358	0.47	ENSG00000221264	.	82958	0.09
chr17_72365655_72365843	0.46	GPR142	G protein-coupled receptor 142	2152	0.2
chr5_56121216_56121683	0.46	MAP3K1	mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase	10048	0.18
chr10_120457476_120457627	0.46	CACUL1	CDK2-associated, cullin domain 1	57207	0.12
chr6_154478833_154479416	0.46	OPRM1	opioid receptor, mu 1	71482	0.12
chr6_45463124_45463523	0.46	RUNX2	runt-related transcription factor 2	73101	0.11
chr5_139030210_139030361	0.46	CXXC5	CXXC finger protein 5	289	0.92
chr11_104480366_104480593	0.46	CASP12	caspase 12 (gene/pseudogene)	288662	0.01
chr13_40670767_40671082	0.45	ENSG00000207458	.	130040	0.06
chr4_123379067_123379218	0.45	IL2	interleukin 2	1262	0.57
chr7_150019104_150019348	0.45	ACTR3C	ARP3 actin-related protein 3 homolog C (yeast)	1026	0.31
chr2_106777844_106778093	0.45	UXS1	UDP-glucuronate decarboxylase 1	887	0.66
chr19_42632588_42632877	0.45	POU2F2	POU class 2 homeobox 2	3811	0.11
chr4_154422696_154422847	0.45	KIAA0922	KIAA0922	35270	0.19
chr6_134495408_134495587	0.45	SGK1	serum/glucocorticoid regulated kinase 1	505	0.81
chr3_71274197_71274348	0.45	FOXP1	forkhead box P1	20044	0.26
chr8_20112422_20112573	0.45	LZTS1	leucine zipper, putative tumor suppressor 1	195	0.94
chr15_93632692_93632897	0.45	RGMA	repulsive guidance molecule family member a	361	0.92
chr2_45478028_45478179	0.45	SIX2	SIX homeobox 2	241534	0.02
chr1_93422949_93423110	0.45	FAM69A	family with sequence similarity 69, member A	4028	0.15
chr14_106327072_106327522	0.45	ENSG00000265714	.	1273	0.08
chr22_31981049_31981318	0.44	SFI1	Sfi1 homolog, spindle assembly associated (yeast)	1291	0.46
chr3_177662901_177663156	0.44	ENSG00000199858	.	62539	0.16
chr16_53544613_53544883	0.44	AKTIP	AKT interacting protein	6425	0.23
chr21_34103959_34104195	0.44	PAXBP1-AS1	PAXBP1 antisense RNA 1	1414	0.35
chr3_71352722_71352944	0.44	FOXP1	forkhead box P1	1078	0.61
chr21_43846854_43847005	0.44	ENSG00000252619	.	9227	0.14
chr2_162852542_162852808	0.44	AC008063.2		77091	0.09
chr4_26961356_26961595	0.44	STIM2	stromal interaction molecule 2	43147	0.2
chrX_9592027_9592178	0.43	TBL1X	transducin (beta)-like 1X-linked	89119	0.09
chr1_200838727_200838878	0.43	GPR25	G protein-coupled receptor 25	3281	0.23
chr14_65905383_65905557	0.43	FUT8	fucosyltransferase 8 (alpha (1,6) fucosyltransferase)	25730	0.2
chr17_35031754_35032157	0.43	MRM1	mitochondrial rRNA methyltransferase 1 homolog (S. cerevisiae)	73564	0.08
chr12_12772516_12772715	0.43	CREBL2	cAMP responsive element binding protein-like 2	7789	0.21
chr1_52083477_52083692	0.43	OSBPL9	oxysterol binding protein-like 9	803	0.68
chr17_73121977_73122246	0.43	NT5C	5', 3'-nucleotidase, cytosolic	5242	0.09
chr4_154415639_154415790	0.43	KIAA0922	KIAA0922	28213	0.21
chr1_161158279_161158521	0.43	ADAMTS4	ADAM metallopeptidase with thrombospondin type 1 motif, 4	10443	0.06
chr4_153000114_153000345	0.43	ENSG00000253077	.	107464	0.07
chr2_240524112_240524372	0.43	AC079612.1	Uncharacterized protein; cDNA FLJ45964 fis, clone PLACE7014396	24247	0.25
chr2_61758031_61758408	0.43	XPO1	exportin 1 (CRM1 homolog, yeast)	3194	0.24
chr2_97628467_97628722	0.43	ENSG00000252845	.	6042	0.16
chr16_3838912_3839326	0.43	CREBBP	CREB binding protein	8251	0.23
chr19_17433702_17433886	0.43	ANO8	anoctamin 8	11844	0.07
chr4_7832948_7833099	0.42	AFAP1	actin filament associated protein 1	40786	0.16
chr5_150631607_150631777	0.42	GM2A	GM2 ganglioside activator	761	0.65
chr19_11664816_11664967	0.42	ELOF1	elongation factor 1 homolog (S. cerevisiae)	718	0.48
chr6_166747055_166747348	0.42	SFT2D1	SFT2 domain containing 1	8878	0.19
chrX_24666059_24666265	0.42	PCYT1B	phosphate cytidylyltransferase 1, choline, beta	809	0.56
chr20_31260771_31260928	0.42	COMMD7	COMM domain containing 7	70363	0.08
chr14_55839531_55839755	0.42	RP11-665C16.5		33424	0.16
chr2_175359311_175359644	0.42	GPR155	G protein-coupled receptor 155	7655	0.2
chr8_99956958_99957335	0.42	OSR2	odd-skipped related transciption factor 2	259	0.9
chr20_1344489_1344952	0.42	RP11-314N13.3		2454	0.22
chr7_76980036_76980207	0.42	GSAP	gamma-secretase activating protein	20437	0.22
chr8_19367752_19367981	0.42	CSGALNACT1	chondroitin sulfate N-acetylgalactosaminyltransferase 1	91510	0.1
chr1_101774544_101774731	0.42	RP4-575N6.5		65923	0.1
chr8_129670035_129670289	0.42	ENSG00000221351	.	161878	0.04
chr6_2023671_2023822	0.42	GMDS	GDP-mannose 4,6-dehydratase	152479	0.04
chr22_20005369_20005520	0.41	TANGO2	transport and golgi organization 2 homolog (Drosophila)	890	0.34
chr2_28475686_28475837	0.41	AC093690.1		57565	0.14
chr1_151027461_151027678	0.41	MLLT11	myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11	2665	0.12
chr6_43244325_43244476	0.41	SLC22A7	solute carrier family 22 (organic anion transporter), member 7	21336	0.11
chr4_143622207_143622596	0.41	INPP4B	inositol polyphosphate-4-phosphatase, type II, 105kDa	140579	0.05
chr10_70384861_70385507	0.41	TET1	tet methylcytosine dioxygenase 1	64771	0.08
chr1_231746267_231746480	0.41	LINC00582	long intergenic non-protein coding RNA 582	1463	0.42
chr19_19718141_19718292	0.41	AC002306.1		1057	0.38
chr13_99911653_99911895	0.41	GPR18	G protein-coupled receptor 18	1092	0.53
chr3_51711887_51712231	0.41	TEX264	testis expressed 264	6148	0.16
chr17_14093316_14093554	0.41	ENSG00000252305	.	12987	0.2
chr2_162928731_162929065	0.41	AC008063.2		868	0.58
chr8_121743626_121743819	0.41	RP11-713M15.1		29771	0.22
chr2_145085983_145086134	0.41	GTDC1	glycosyltransferase-like domain containing 1	4025	0.35
chr22_23793387_23793538	0.41	ZDHHC8P1	zinc finger, DHHC-type containing 8 pseudogene 1	49118	0.12
chr3_87842915_87843066	0.41	ENSG00000200703	.	51191	0.17
chr11_6459562_6459838	0.41	HPX	hemopexin	2594	0.18
chr11_12165537_12165696	0.41	MICAL2	microtubule associated monooxygenase, calponin and LIM domain containing 2	5646	0.3
chr12_68759301_68759452	0.40	MDM1	Mdm1 nuclear protein homolog (mouse)	33215	0.21
chr12_65008891_65009217	0.40	RASSF3	Ras association (RalGDS/AF-6) domain family member 3	4761	0.14
chr3_17049819_17049970	0.40	PLCL2	phospholipase C-like 2	2092	0.39
chrX_123529862_123530058	0.40	SH2D1A	SH2 domain containing 1A	49521	0.19
chr6_144675907_144676058	0.40	UTRN	utrophin	10745	0.25
chr14_102818626_102818777	0.40	ENSG00000239061	.	6538	0.13
chr4_109056844_109057272	0.40	LEF1	lymphoid enhancer-binding factor 1	30399	0.19
chr2_196396233_196396389	0.40	ENSG00000202206	.	17551	0.25
chr16_3623403_3623748	0.40	NLRC3	NLR family, CARD domain containing 3	3817	0.17
chr7_132938245_132938484	0.40	EXOC4	exocyst complex component 4	236	0.95
chr11_63307656_63307807	0.40	RARRES3	retinoic acid receptor responder (tazarotene induced) 3	1863	0.28
chr3_71530793_71531298	0.40	ENSG00000221264	.	60195	0.13
chr1_208055973_208056124	0.40	CD34	CD34 molecule	7789	0.29
chr6_157246079_157246230	0.40	ARID1B	AT rich interactive domain 1B (SWI1-like)	23647	0.26
chr14_57527452_57527603	0.40	AL391152.1		144361	0.04
chr12_88433053_88433204	0.40	C12orf29	chromosome 12 open reading frame 29	3905	0.22
chr20_42649596_42649747	0.40	ENSG00000241229	.	13783	0.22
chr6_71382388_71382539	0.40	SMAP1	small ArfGAP 1	4842	0.32
chr14_78219731_78219882	0.39	C14orf178	chromosome 14 open reading frame 178	7367	0.14
chr10_97531333_97531484	0.39	ENTPD1	ectonucleoside triphosphate diphosphohydrolase 1	15694	0.21
chr10_11248795_11249171	0.39	RP3-323N1.2		35644	0.17
chr1_169640913_169641224	0.39	SELL	selectin L	39771	0.13
chr16_71828949_71829476	0.39	AP1G1	adaptor-related protein complex 1, gamma 1 subunit	12985	0.13
chr6_114287058_114287209	0.39	HDAC2	histone deacetylase 2	2561	0.27
chr1_31215274_31215425	0.39	ENSG00000264773	.	3270	0.2
chr17_16920000_16920415	0.39	MPRIP	myosin phosphatase Rho interacting protein	25652	0.15
chr15_43444066_43444217	0.39	TMEM62	transmembrane protein 62	17661	0.14
chr16_27389354_27389583	0.39	IL21R	interleukin 21 receptor	24015	0.17
chr16_3858533_3859115	0.39	CREBBP	CREB binding protein	27956	0.18
chr9_123607204_123607355	0.39	PSMD5-AS1	PSMD5 antisense RNA 1 (head to head)	127	0.95
chr15_31561641_31561994	0.39	KLF13	Kruppel-like factor 13	57241	0.15
chr14_90217677_90217828	0.39	ENSG00000200312	.	38897	0.17

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of PROX1

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	0.8	GO:0033152	immunoglobulin V(D)J recombination(GO:0033152)
0.1	0.6	GO:0030854	positive regulation of granulocyte differentiation(GO:0030854)
0.1	0.4	GO:0001831	trophectodermal cellular morphogenesis(GO:0001831)
0.1	0.4	GO:0046548	retinal rod cell development(GO:0046548)
0.1	0.9	GO:0045066	regulatory T cell differentiation(GO:0045066)
0.1	0.4	GO:0042091	interleukin-10 biosynthetic process(GO:0042091) regulation of interleukin-10 biosynthetic process(GO:0045074)
0.1	0.5	GO:0061029	eyelid development in camera-type eye(GO:0061029)
0.1	0.1	GO:0002326	B cell lineage commitment(GO:0002326)
0.1	0.3	GO:0018076	N-terminal peptidyl-lysine acetylation(GO:0018076)
0.1	0.4	GO:0006689	ganglioside catabolic process(GO:0006689)
0.1	0.4	GO:0002691	regulation of cellular extravasation(GO:0002691)
0.1	0.5	GO:0045898	regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045898)
0.1	0.3	GO:0006922	obsolete cleavage of lamin involved in execution phase of apoptosis(GO:0006922)
0.1	0.3	GO:0010040	response to iron(II) ion(GO:0010040)
0.1	0.3	GO:0045722	positive regulation of gluconeogenesis(GO:0045722)
0.1	0.3	GO:0021869	forebrain ventricular zone progenitor cell division(GO:0021869)
0.1	0.3	GO:0017121	phospholipid scrambling(GO:0017121)
0.1	0.1	GO:0002523	leukocyte migration involved in inflammatory response(GO:0002523)
0.1	0.2	GO:0009189	deoxyribonucleoside diphosphate biosynthetic process(GO:0009189)
0.1	0.3	GO:0060632	regulation of microtubule-based movement(GO:0060632)
0.1	0.3	GO:0060088	auditory receptor cell morphogenesis(GO:0002093) auditory receptor cell stereocilium organization(GO:0060088)
0.1	0.2	GO:0007000	nucleolus organization(GO:0007000)
0.1	0.3	GO:0022614	membrane to membrane docking(GO:0022614)
0.1	0.2	GO:0060136	embryonic process involved in female pregnancy(GO:0060136)
0.1	0.3	GO:0042635	positive regulation of hair cycle(GO:0042635) positive regulation of hair follicle development(GO:0051798)
0.1	0.3	GO:0006346	methylation-dependent chromatin silencing(GO:0006346)
0.1	0.1	GO:0010916	regulation of very-low-density lipoprotein particle clearance(GO:0010915) negative regulation of very-low-density lipoprotein particle clearance(GO:0010916)
0.1	0.4	GO:0085020	protein K6-linked ubiquitination(GO:0085020)
0.1	0.2	GO:0060394	negative regulation of pathway-restricted SMAD protein phosphorylation(GO:0060394)
0.1	0.2	GO:0070601	centromeric sister chromatid cohesion(GO:0070601) regulation of centromeric sister chromatid cohesion(GO:0070602)
0.1	0.6	GO:0045022	early endosome to late endosome transport(GO:0045022) vesicle-mediated transport between endosomal compartments(GO:0098927)
0.1	0.3	GO:0002710	negative regulation of T cell mediated immunity(GO:0002710)
0.1	0.2	GO:0034392	negative regulation of smooth muscle cell apoptotic process(GO:0034392)
0.1	0.5	GO:0006491	N-glycan processing(GO:0006491)
0.1	0.2	GO:0019276	UDP-N-acetylgalactosamine metabolic process(GO:0019276)
0.1	0.3	GO:0016556	mRNA modification(GO:0016556)
0.1	0.2	GO:0002830	positive regulation of type 2 immune response(GO:0002830)
0.1	0.5	GO:0007172	signal complex assembly(GO:0007172)
0.1	0.3	GO:0019987	obsolete negative regulation of anti-apoptosis(GO:0019987)
0.1	0.2	GO:0006391	transcription initiation from mitochondrial promoter(GO:0006391)
0.1	0.3	GO:0070670	response to interleukin-4(GO:0070670)
0.1	0.2	GO:0042504	tyrosine phosphorylation of Stat4 protein(GO:0042504) regulation of tyrosine phosphorylation of Stat4 protein(GO:0042519) positive regulation of tyrosine phosphorylation of Stat4 protein(GO:0042520)
0.1	0.2	GO:0061030	epithelial cell differentiation involved in mammary gland alveolus development(GO:0061030)
0.1	0.2	GO:0002335	mature B cell differentiation(GO:0002335)
0.1	0.4	GO:0060216	definitive hemopoiesis(GO:0060216)
0.1	0.7	GO:0045648	positive regulation of erythrocyte differentiation(GO:0045648)
0.1	0.3	GO:0051593	response to folic acid(GO:0051593)
0.1	0.2	GO:0034063	stress granule assembly(GO:0034063)
0.1	0.2	GO:0045348	positive regulation of MHC class II biosynthetic process(GO:0045348)
0.1	0.3	GO:0042535	positive regulation of tumor necrosis factor biosynthetic process(GO:0042535)
0.1	0.2	GO:0035405	histone-threonine phosphorylation(GO:0035405)
0.1	0.2	GO:0071481	cellular response to X-ray(GO:0071481)
0.1	0.2	GO:0015015	heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.1	0.2	GO:0051657	maintenance of organelle location(GO:0051657)
0.0	0.0	GO:0071801	regulation of podosome assembly(GO:0071801) positive regulation of podosome assembly(GO:0071803)
0.0	0.1	GO:0051152	positive regulation of smooth muscle cell differentiation(GO:0051152)
0.0	0.1	GO:0002902	B cell apoptotic process(GO:0001783) regulation of B cell apoptotic process(GO:0002902)
0.0	0.2	GO:0008053	mitochondrial fusion(GO:0008053)
0.0	0.1	GO:0032506	cytokinetic process(GO:0032506)
0.0	0.1	GO:0045343	MHC class I biosynthetic process(GO:0045341) regulation of MHC class I biosynthetic process(GO:0045343)
0.0	0.1	GO:0050862	positive regulation of T cell receptor signaling pathway(GO:0050862)
0.0	0.1	GO:0032914	positive regulation of transforming growth factor beta1 production(GO:0032914)
0.0	0.1	GO:0040016	embryonic cleavage(GO:0040016)
0.0	0.6	GO:0006607	NLS-bearing protein import into nucleus(GO:0006607)
0.0	0.2	GO:0006591	ornithine metabolic process(GO:0006591)
0.0	0.6	GO:0006385	transcription elongation from RNA polymerase III promoter(GO:0006385) termination of RNA polymerase III transcription(GO:0006386)
0.0	0.0	GO:0003402	planar cell polarity pathway involved in axis elongation(GO:0003402)
0.0	0.1	GO:0010761	fibroblast migration(GO:0010761)
0.0	0.1	GO:0046642	negative regulation of alpha-beta T cell proliferation(GO:0046642)
0.0	0.2	GO:0048548	regulation of pinocytosis(GO:0048548)
0.0	0.3	GO:0050710	negative regulation of cytokine secretion(GO:0050710)
0.0	0.1	GO:0016553	base conversion or substitution editing(GO:0016553)
0.0	0.2	GO:0002726	positive regulation of T cell cytokine production(GO:0002726)
0.0	0.2	GO:0090400	stress-induced premature senescence(GO:0090400)
0.0	0.2	GO:1901339	activation of store-operated calcium channel activity(GO:0032237) regulation of store-operated calcium channel activity(GO:1901339) positive regulation of store-operated calcium channel activity(GO:1901341)
0.0	0.2	GO:0043457	regulation of cellular respiration(GO:0043457)
0.0	0.2	GO:0031936	negative regulation of chromatin silencing(GO:0031936)
0.0	0.2	GO:0048261	negative regulation of receptor-mediated endocytosis(GO:0048261)
0.0	0.2	GO:0007256	activation of JNKK activity(GO:0007256)
0.0	0.0	GO:2000188	regulation of cholesterol homeostasis(GO:2000188) positive regulation of cholesterol homeostasis(GO:2000189)
0.0	0.1	GO:0090382	phagolysosome assembly(GO:0001845) phagosome maturation(GO:0090382)
0.0	0.2	GO:0042761	very long-chain fatty acid biosynthetic process(GO:0042761)
0.0	0.1	GO:0030011	maintenance of cell polarity(GO:0030011)
0.0	0.2	GO:0032367	intracellular sterol transport(GO:0032366) intracellular cholesterol transport(GO:0032367)
0.0	0.1	GO:0008054	negative regulation of cyclin-dependent protein serine/threonine kinase by cyclin degradation(GO:0008054)
0.0	0.1	GO:0060596	mammary placode formation(GO:0060596)
0.0	0.2	GO:0032667	interleukin-23 production(GO:0032627) regulation of interleukin-23 production(GO:0032667) positive regulation of interleukin-23 production(GO:0032747)
0.0	0.3	GO:0006198	cAMP catabolic process(GO:0006198)
0.0	0.2	GO:0042104	positive regulation of activated T cell proliferation(GO:0042104)
0.0	0.2	GO:0043368	positive T cell selection(GO:0043368)
0.0	0.3	GO:0044091	membrane biogenesis(GO:0044091)
0.0	0.0	GO:0045945	positive regulation of transcription from RNA polymerase III promoter(GO:0045945)
0.0	0.3	GO:0043508	negative regulation of JUN kinase activity(GO:0043508)
0.0	0.2	GO:0010759	positive regulation of macrophage chemotaxis(GO:0010759)
0.0	0.1	GO:0002925	positive regulation of humoral immune response mediated by circulating immunoglobulin(GO:0002925)
0.0	0.1	GO:0035609	C-terminal protein deglutamylation(GO:0035609) protein side chain deglutamylation(GO:0035610)
0.0	0.1	GO:0090322	regulation of superoxide metabolic process(GO:0090322)
0.0	0.3	GO:0070076	histone lysine demethylation(GO:0070076)
0.0	0.3	GO:0043550	regulation of lipid kinase activity(GO:0043550)
0.0	0.1	GO:0045767	obsolete regulation of anti-apoptosis(GO:0045767)
0.0	0.1	GO:0033522	histone H2A ubiquitination(GO:0033522)
0.0	0.2	GO:0032099	negative regulation of appetite(GO:0032099)
0.0	0.1	GO:0032790	ribosome disassembly(GO:0032790)
0.0	0.1	GO:0060124	positive regulation of growth hormone secretion(GO:0060124)
0.0	0.1	GO:0040015	negative regulation of multicellular organism growth(GO:0040015)
0.0	0.2	GO:0046719	intracellular transport of viral protein in host cell(GO:0019060) symbiont intracellular protein transport in host(GO:0030581) regulation by virus of viral protein levels in host cell(GO:0046719) intracellular protein transport in other organism involved in symbiotic interaction(GO:0051708)
0.0	0.1	GO:0010957	negative regulation of calcidiol 1-monooxygenase activity(GO:0010956) negative regulation of vitamin D biosynthetic process(GO:0010957) negative regulation of vitamin metabolic process(GO:0046137)
0.0	0.1	GO:0001766	membrane raft polarization(GO:0001766) membrane raft distribution(GO:0031580)
0.0	0.1	GO:0032966	negative regulation of collagen biosynthetic process(GO:0032966)
0.0	0.0	GO:0061154	endothelial tube morphogenesis(GO:0061154)
0.0	0.1	GO:0003100	regulation of systemic arterial blood pressure by endothelin(GO:0003100)
0.0	0.1	GO:0006686	sphingomyelin biosynthetic process(GO:0006686)
0.0	0.1	GO:0035305	negative regulation of dephosphorylation(GO:0035305) negative regulation of protein dephosphorylation(GO:0035308)
0.0	0.1	GO:0071428	rRNA-containing ribonucleoprotein complex export from nucleus(GO:0071428)
0.0	0.1	GO:0001778	plasma membrane repair(GO:0001778)
0.0	0.1	GO:0061298	retina vasculature development in camera-type eye(GO:0061298) retina vasculature morphogenesis in camera-type eye(GO:0061299)
0.0	0.1	GO:0045112	integrin biosynthetic process(GO:0045112)
0.0	0.1	GO:0006384	transcription initiation from RNA polymerase III promoter(GO:0006384)
0.0	0.1	GO:0033632	regulation of cell-cell adhesion mediated by integrin(GO:0033632)
0.0	0.8	GO:0050690	regulation of defense response to virus by virus(GO:0050690)
0.0	0.0	GO:0022030	cerebral cortex radial glia guided migration(GO:0021801) telencephalon glial cell migration(GO:0022030)
0.0	0.0	GO:0002227	innate immune response in mucosa(GO:0002227) mucosal immune response(GO:0002385)
0.0	0.1	GO:0031558	obsolete induction of apoptosis in response to chemical stimulus(GO:0031558)
0.0	0.1	GO:0030812	negative regulation of nucleotide catabolic process(GO:0030812)
0.0	0.1	GO:0042416	dopamine biosynthetic process(GO:0042416)
0.0	0.1	GO:0097576	vacuole fusion(GO:0097576)
0.0	0.1	GO:0060662	tube lumen cavitation(GO:0060605) salivary gland cavitation(GO:0060662)
0.0	0.1	GO:0045292	mRNA cis splicing, via spliceosome(GO:0045292)
0.0	0.1	GO:0010642	negative regulation of platelet-derived growth factor receptor signaling pathway(GO:0010642)
0.0	0.1	GO:0021797	forebrain anterior/posterior pattern specification(GO:0021797)
0.0	0.3	GO:0043666	regulation of phosphoprotein phosphatase activity(GO:0043666)
0.0	0.1	GO:0010587	miRNA metabolic process(GO:0010586) miRNA catabolic process(GO:0010587)
0.0	0.1	GO:0017183	peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183)
0.0	0.0	GO:0032661	interleukin-18 production(GO:0032621) regulation of interleukin-18 production(GO:0032661)
0.0	0.1	GO:0060710	chorio-allantoic fusion(GO:0060710)
0.0	0.3	GO:0019059	obsolete initiation of viral infection(GO:0019059)
0.0	0.1	GO:0019885	antigen processing and presentation of endogenous peptide antigen(GO:0002483) antigen processing and presentation of endogenous peptide antigen via MHC class I(GO:0019885)
0.0	0.2	GO:0035434	copper ion transmembrane transport(GO:0035434)
0.0	0.2	GO:0043558	regulation of translational initiation in response to stress(GO:0043558)
0.0	0.1	GO:0019372	lipoxygenase pathway(GO:0019372)
0.0	0.1	GO:0070682	proteasome regulatory particle assembly(GO:0070682)
0.0	0.1	GO:0006189	'de novo' IMP biosynthetic process(GO:0006189)
0.0	0.2	GO:0060158	phospholipase C-activating dopamine receptor signaling pathway(GO:0060158)
0.0	0.1	GO:0006930	substrate-dependent cell migration, cell extension(GO:0006930)
0.0	0.1	GO:0006998	nuclear envelope organization(GO:0006998)
0.0	0.2	GO:0006538	glutamate catabolic process(GO:0006538)
0.0	0.1	GO:0000012	single strand break repair(GO:0000012)
0.0	0.1	GO:0048096	chromatin-mediated maintenance of transcription(GO:0048096)
0.0	0.0	GO:0009214	cyclic nucleotide catabolic process(GO:0009214)
0.0	0.1	GO:0009296	obsolete flagellum assembly(GO:0009296)
0.0	0.2	GO:0045822	negative regulation of heart contraction(GO:0045822)
0.0	0.1	GO:0032100	positive regulation of response to food(GO:0032097) positive regulation of appetite(GO:0032100)
0.0	0.1	GO:0071392	cellular response to estradiol stimulus(GO:0071392)
0.0	0.1	GO:0000729	DNA double-strand break processing(GO:0000729)
0.0	0.0	GO:0001302	replicative cell aging(GO:0001302)
0.0	0.1	GO:0001705	ectoderm formation(GO:0001705)
0.0	0.1	GO:0007097	nuclear migration(GO:0007097)
0.0	0.2	GO:0006002	fructose 6-phosphate metabolic process(GO:0006002)
0.0	0.2	GO:0043568	positive regulation of insulin-like growth factor receptor signaling pathway(GO:0043568)
0.0	0.1	GO:1901522	positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus(GO:1901522)
0.0	0.1	GO:0032922	circadian regulation of gene expression(GO:0032922)
0.0	0.1	GO:0007008	outer mitochondrial membrane organization(GO:0007008) protein import into mitochondrial outer membrane(GO:0045040)
0.0	0.1	GO:0001661	conditioned taste aversion(GO:0001661)
0.0	0.2	GO:0000303	response to superoxide(GO:0000303)
0.0	0.1	GO:1902745	positive regulation of lamellipodium assembly(GO:0010592) positive regulation of lamellipodium organization(GO:1902745)
0.0	0.1	GO:0021754	facial nucleus development(GO:0021754)
0.0	0.2	GO:0006349	regulation of gene expression by genetic imprinting(GO:0006349)
0.0	0.0	GO:0070254	mucus secretion(GO:0070254)
0.0	0.1	GO:0007035	vacuolar acidification(GO:0007035)
0.0	0.1	GO:0045875	negative regulation of sister chromatid cohesion(GO:0045875)
0.0	0.1	GO:0018027	peptidyl-lysine dimethylation(GO:0018027)
0.0	0.3	GO:0031146	SCF-dependent proteasomal ubiquitin-dependent protein catabolic process(GO:0031146)
0.0	0.5	GO:0007190	activation of adenylate cyclase activity(GO:0007190)
0.0	0.0	GO:0045672	positive regulation of osteoclast differentiation(GO:0045672)
0.0	0.1	GO:0000301	retrograde transport, vesicle recycling within Golgi(GO:0000301)
0.0	0.1	GO:0006420	arginyl-tRNA aminoacylation(GO:0006420)
0.0	0.1	GO:0015917	aminophospholipid transport(GO:0015917)
0.0	0.1	GO:0034616	response to laminar fluid shear stress(GO:0034616)
0.0	0.1	GO:0006929	substrate-dependent cell migration(GO:0006929)
0.0	0.0	GO:0042109	lymphotoxin A production(GO:0032641) lymphotoxin A biosynthetic process(GO:0042109)
0.0	0.2	GO:1903078	positive regulation of establishment of protein localization to plasma membrane(GO:0090004) positive regulation of protein localization to plasma membrane(GO:1903078) positive regulation of protein localization to cell periphery(GO:1904377)
0.0	0.4	GO:0033209	tumor necrosis factor-mediated signaling pathway(GO:0033209)
0.0	0.1	GO:0000103	sulfate assimilation(GO:0000103)
0.0	0.0	GO:0043951	negative regulation of cAMP-mediated signaling(GO:0043951)
0.0	0.2	GO:0000050	urea cycle(GO:0000050)
0.0	0.1	GO:0071549	cellular response to dexamethasone stimulus(GO:0071549)
0.0	0.0	GO:0021570	rhombomere 4 development(GO:0021570)
0.0	0.2	GO:0048205	COPI-coated vesicle budding(GO:0035964) Golgi vesicle budding(GO:0048194) Golgi transport vesicle coating(GO:0048200) COPI coating of Golgi vesicle(GO:0048205)
0.0	0.2	GO:0030206	chondroitin sulfate biosynthetic process(GO:0030206)
0.0	0.0	GO:0046940	nucleoside monophosphate phosphorylation(GO:0046940)
0.0	0.0	GO:0010831	positive regulation of myotube differentiation(GO:0010831)
0.0	0.2	GO:0006657	CDP-choline pathway(GO:0006657)
0.0	0.3	GO:0032012	regulation of ARF protein signal transduction(GO:0032012)
0.0	0.1	GO:0006290	pyrimidine dimer repair(GO:0006290)
0.0	0.1	GO:0033962	cytoplasmic mRNA processing body assembly(GO:0033962)
0.0	0.1	GO:1904181	positive regulation of mitochondrial depolarization(GO:0051901) positive regulation of membrane depolarization(GO:1904181)
0.0	0.2	GO:1905144	G-protein coupled acetylcholine receptor signaling pathway(GO:0007213) cellular response to ammonium ion(GO:0071242) acetylcholine receptor signaling pathway(GO:0095500) postsynaptic signal transduction(GO:0098926) signal transduction involved in cellular response to ammonium ion(GO:1903831) response to acetylcholine(GO:1905144) cellular response to acetylcholine(GO:1905145)
0.0	0.1	GO:0045793	positive regulation of cell size(GO:0045793)
0.0	0.2	GO:0046519	sphingoid metabolic process(GO:0046519)
0.0	0.1	GO:0006390	mitochondrial RNA metabolic process(GO:0000959) transcription from mitochondrial promoter(GO:0006390)
0.0	0.1	GO:0042117	monocyte activation(GO:0042117)
0.0	0.0	GO:0032098	regulation of appetite(GO:0032098)
0.0	0.2	GO:0044766	multi-organism transport(GO:0044766) transport of virus(GO:0046794) intracellular transport of virus(GO:0075733) multi-organism localization(GO:1902579) multi-organism intracellular transport(GO:1902583)
0.0	0.1	GO:0030186	melatonin metabolic process(GO:0030186) melatonin biosynthetic process(GO:0030187)
0.0	0.1	GO:0042989	sequestering of actin monomers(GO:0042989)
0.0	0.3	GO:0042273	ribosomal large subunit biogenesis(GO:0042273)
0.0	0.0	GO:0030505	inorganic diphosphate transport(GO:0030505)
0.0	0.1	GO:0051085	chaperone mediated protein folding requiring cofactor(GO:0051085)
0.0	0.3	GO:0046834	lipid phosphorylation(GO:0046834)
0.0	0.0	GO:0060084	synaptic transmission involved in micturition(GO:0060084)
0.0	0.0	GO:0097709	connective tissue replacement involved in inflammatory response wound healing(GO:0002248) connective tissue replacement(GO:0097709)
0.0	0.1	GO:0032876	regulation of DNA endoreduplication(GO:0032875) negative regulation of DNA endoreduplication(GO:0032876) DNA endoreduplication(GO:0042023)
0.0	0.1	GO:0048013	ephrin receptor signaling pathway(GO:0048013)
0.0	0.1	GO:0008354	germ cell migration(GO:0008354)
0.0	0.0	GO:0060999	positive regulation of dendritic spine development(GO:0060999)
0.0	0.1	GO:0009713	catechol-containing compound biosynthetic process(GO:0009713) catecholamine biosynthetic process(GO:0042423)
0.0	0.1	GO:0046827	positive regulation of protein export from nucleus(GO:0046827)
0.0	0.1	GO:0030910	olfactory placode formation(GO:0030910) olfactory placode development(GO:0071698) olfactory placode morphogenesis(GO:0071699)
0.0	0.2	GO:0008625	extrinsic apoptotic signaling pathway via death domain receptors(GO:0008625) extrinsic apoptotic signaling pathway(GO:0097191)
0.0	0.0	GO:0042362	fat-soluble vitamin biosynthetic process(GO:0042362)
0.0	0.1	GO:0006685	sphingomyelin catabolic process(GO:0006685)
0.0	1.1	GO:0050852	T cell receptor signaling pathway(GO:0050852)
0.0	0.1	GO:0031116	positive regulation of microtubule polymerization(GO:0031116)
0.0	0.0	GO:0071514	genetic imprinting(GO:0071514)
0.0	0.1	GO:0040023	establishment of nucleus localization(GO:0040023)
0.0	0.1	GO:0015781	pyrimidine nucleotide-sugar transport(GO:0015781)
0.0	0.0	GO:0070897	RNA polymerase II transcriptional preinitiation complex assembly(GO:0051123) DNA-templated transcriptional preinitiation complex assembly(GO:0070897)
0.0	0.2	GO:0042135	neurotransmitter catabolic process(GO:0042135)
0.0	0.6	GO:0042059	negative regulation of epidermal growth factor receptor signaling pathway(GO:0042059) negative regulation of ERBB signaling pathway(GO:1901185)
0.0	0.1	GO:0060263	regulation of respiratory burst(GO:0060263)
0.0	0.0	GO:0060449	bud elongation involved in lung branching(GO:0060449)
0.0	0.0	GO:0046449	allantoin metabolic process(GO:0000255) creatinine metabolic process(GO:0046449) cellular lactam metabolic process(GO:0072338)
0.0	0.0	GO:0045085	negative regulation of interleukin-2 biosynthetic process(GO:0045085)
0.0	0.1	GO:0009405	pathogenesis(GO:0009405)
0.0	0.0	GO:0002085	inhibition of neuroepithelial cell differentiation(GO:0002085)
0.0	0.8	GO:0006968	cellular defense response(GO:0006968)
0.0	0.1	GO:0002052	positive regulation of neuroblast proliferation(GO:0002052)
0.0	0.0	GO:0048532	anatomical structure arrangement(GO:0048532)
0.0	0.1	GO:0072583	synaptic vesicle recycling(GO:0036465) synaptic vesicle endocytosis(GO:0048488) clathrin-mediated endocytosis(GO:0072583)
0.0	0.0	GO:0070634	transepithelial ammonium transport(GO:0070634)
0.0	0.1	GO:0016255	attachment of GPI anchor to protein(GO:0016255)
0.0	0.0	GO:0010939	regulation of necrotic cell death(GO:0010939)
0.0	0.3	GO:0032945	negative regulation of mononuclear cell proliferation(GO:0032945) negative regulation of lymphocyte proliferation(GO:0050672)
0.0	0.1	GO:0070493	thrombin receptor signaling pathway(GO:0070493)
0.0	0.1	GO:0050667	homocysteine metabolic process(GO:0050667)
0.0	0.0	GO:0048149	behavioral response to ethanol(GO:0048149)
0.0	0.0	GO:0010901	regulation of very-low-density lipoprotein particle remodeling(GO:0010901)
0.0	0.0	GO:0070229	negative regulation of lymphocyte apoptotic process(GO:0070229)
0.0	0.2	GO:0042531	positive regulation of tyrosine phosphorylation of STAT protein(GO:0042531)
0.0	0.0	GO:0018125	peptidyl-cysteine methylation(GO:0018125)
0.0	0.0	GO:0010985	negative regulation of lipoprotein particle clearance(GO:0010985)
0.0	0.3	GO:0018298	protein-chromophore linkage(GO:0018298)
0.0	0.0	GO:0021779	spinal cord oligodendrocyte cell differentiation(GO:0021529) spinal cord oligodendrocyte cell fate specification(GO:0021530) oligodendrocyte cell fate specification(GO:0021778) oligodendrocyte cell fate commitment(GO:0021779) glial cell fate specification(GO:0021780)
0.0	0.1	GO:0006359	regulation of transcription from RNA polymerase III promoter(GO:0006359)
0.0	0.1	GO:0007386	compartment pattern specification(GO:0007386)
0.0	0.1	GO:0060259	regulation of feeding behavior(GO:0060259)
0.0	0.1	GO:0034260	negative regulation of GTPase activity(GO:0034260)
0.0	0.1	GO:0006983	ER overload response(GO:0006983)
0.0	0.1	GO:0008608	attachment of spindle microtubules to kinetochore(GO:0008608)
0.0	0.0	GO:0060081	membrane hyperpolarization(GO:0060081)
0.0	0.2	GO:0006801	superoxide metabolic process(GO:0006801)
0.0	0.2	GO:0016578	histone deubiquitination(GO:0016578)
0.0	0.0	GO:0071503	response to heparin(GO:0071503)
0.0	0.2	GO:0006611	protein export from nucleus(GO:0006611)
0.0	0.0	GO:0010979	regulation of vitamin D 24-hydroxylase activity(GO:0010979) positive regulation of vitamin D 24-hydroxylase activity(GO:0010980)
0.0	0.1	GO:0010633	negative regulation of epithelial cell migration(GO:0010633)
0.0	0.0	GO:0001833	inner cell mass cell proliferation(GO:0001833)
0.0	0.2	GO:0003009	skeletal muscle contraction(GO:0003009)
0.0	0.2	GO:0043968	histone H2A acetylation(GO:0043968)
0.0	0.0	GO:0071542	dopaminergic neuron differentiation(GO:0071542)
0.0	0.2	GO:0030032	lamellipodium assembly(GO:0030032)
0.0	0.0	GO:0002666	T cell tolerance induction(GO:0002517) regulation of T cell tolerance induction(GO:0002664) positive regulation of T cell tolerance induction(GO:0002666)
0.0	0.1	GO:0048617	embryonic foregut morphogenesis(GO:0048617)
0.0	0.1	GO:0051044	positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
0.0	0.0	GO:0006678	glucosylceramide metabolic process(GO:0006678)
0.0	0.1	GO:0042074	cell migration involved in gastrulation(GO:0042074)
0.0	0.1	GO:0007158	neuron cell-cell adhesion(GO:0007158)
0.0	0.1	GO:0043537	negative regulation of blood vessel endothelial cell migration(GO:0043537)
0.0	0.0	GO:0000244	spliceosomal tri-snRNP complex assembly(GO:0000244)
0.0	0.1	GO:0014003	oligodendrocyte development(GO:0014003)
0.0	0.1	GO:0006273	lagging strand elongation(GO:0006273)
0.0	0.1	GO:0051546	keratinocyte migration(GO:0051546)
0.0	0.3	GO:0016236	macroautophagy(GO:0016236)
0.0	0.2	GO:0030101	natural killer cell activation(GO:0030101)
0.0	0.0	GO:0045730	respiratory burst(GO:0045730)
0.0	0.1	GO:0008653	lipopolysaccharide metabolic process(GO:0008653)
0.0	0.1	GO:0006104	succinyl-CoA metabolic process(GO:0006104)
0.0	0.1	GO:0031848	protection from non-homologous end joining at telomere(GO:0031848) telomere maintenance in response to DNA damage(GO:0043247)
0.0	0.0	GO:0010867	positive regulation of triglyceride biosynthetic process(GO:0010867)
0.0	0.1	GO:0006362	transcription elongation from RNA polymerase I promoter(GO:0006362)
0.0	0.0	GO:0002360	T cell lineage commitment(GO:0002360)
0.0	0.0	GO:0032328	alanine transport(GO:0032328)
0.0	0.0	GO:0017085	response to insecticide(GO:0017085)
0.0	0.1	GO:1904031	positive regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045737) positive regulation of cyclin-dependent protein kinase activity(GO:1904031)
0.0	0.1	GO:0031017	exocrine pancreas development(GO:0031017)
0.0	0.0	GO:0051608	histamine transport(GO:0051608)
0.0	0.0	GO:0006978	DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:0006978)
0.0	0.0	GO:0006772	thiamine metabolic process(GO:0006772)
0.0	0.0	GO:0052251	induction by organism of defense response of other organism involved in symbiotic interaction(GO:0052251)
0.0	0.1	GO:0050910	detection of mechanical stimulus involved in sensory perception of sound(GO:0050910)
0.0	0.1	GO:0050482	arachidonic acid secretion(GO:0050482) arachidonate transport(GO:1903963)
0.0	0.1	GO:0009133	nucleoside diphosphate biosynthetic process(GO:0009133)
0.0	0.1	GO:0042769	DNA damage response, detection of DNA damage(GO:0042769)
0.0	0.0	GO:0060285	cilium-dependent cell motility(GO:0060285)
0.0	0.1	GO:0032456	endocytic recycling(GO:0032456)
0.0	0.0	GO:0071360	cellular response to exogenous dsRNA(GO:0071360)
0.0	0.1	GO:0008628	hormone-mediated apoptotic signaling pathway(GO:0008628)
0.0	0.1	GO:0051205	protein insertion into membrane(GO:0051205)
0.0	0.1	GO:0003214	cardiac left ventricle morphogenesis(GO:0003214)
0.0	0.3	GO:0046320	regulation of fatty acid oxidation(GO:0046320)
0.0	0.0	GO:0051103	DNA ligation involved in DNA repair(GO:0051103)
0.0	0.0	GO:0002430	complement receptor mediated signaling pathway(GO:0002430)
0.0	0.1	GO:0000381	regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.0	0.9	GO:0060337	type I interferon signaling pathway(GO:0060337) cellular response to type I interferon(GO:0071357)
0.0	0.2	GO:0042771	intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator(GO:0042771)
0.0	0.1	GO:0009143	nucleoside triphosphate catabolic process(GO:0009143)
0.0	0.0	GO:0040009	regulation of growth rate(GO:0040009)
0.0	0.4	GO:0050772	positive regulation of axonogenesis(GO:0050772)
0.0	0.1	GO:0010739	positive regulation of protein kinase A signaling(GO:0010739)
0.0	0.2	GO:0001522	pseudouridine synthesis(GO:0001522)
0.0	0.1	GO:0006857	oligopeptide transport(GO:0006857)
0.0	0.0	GO:0019042	viral latency(GO:0019042)
0.0	0.1	GO:0032486	Rap protein signal transduction(GO:0032486)
0.0	0.0	GO:0002329	immature B cell differentiation(GO:0002327) pre-B cell differentiation(GO:0002329)
0.0	0.1	GO:0072148	epithelial cell fate commitment(GO:0072148)
0.0	0.0	GO:0007063	regulation of sister chromatid cohesion(GO:0007063)
0.0	0.1	GO:0007512	adult heart development(GO:0007512)
0.0	0.1	GO:0071168	protein localization to chromatin(GO:0071168)
0.0	0.1	GO:0008633	obsolete activation of pro-apoptotic gene products(GO:0008633)
0.0	0.0	GO:0051182	coenzyme transport(GO:0051182)
0.0	0.0	GO:0052255	modulation by symbiont of host defense response(GO:0052031) modulation by organism of defense response of other organism involved in symbiotic interaction(GO:0052255) positive regulation by symbiont of host defense response(GO:0052509) positive regulation by organism of defense response of other organism involved in symbiotic interaction(GO:0052510) modulation by organism of immune response of other organism involved in symbiotic interaction(GO:0052552) modulation by symbiont of host immune response(GO:0052553) response to immune response of other organism involved in symbiotic interaction(GO:0052564) response to host immune response(GO:0052572)
0.0	0.0	GO:0006434	seryl-tRNA aminoacylation(GO:0006434)
0.0	0.0	GO:0045416	positive regulation of interleukin-8 biosynthetic process(GO:0045416)
0.0	0.1	GO:0006361	transcription initiation from RNA polymerase I promoter(GO:0006361)
0.0	0.1	GO:0006911	phagocytosis, engulfment(GO:0006911) membrane invagination(GO:0010324)
0.0	0.1	GO:0060013	righting reflex(GO:0060013)
0.0	0.0	GO:0046185	aldehyde catabolic process(GO:0046185)
0.0	0.0	GO:0060665	regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling(GO:0060665)
0.0	0.3	GO:0000289	nuclear-transcribed mRNA poly(A) tail shortening(GO:0000289)
0.0	0.0	GO:0015816	glycine transport(GO:0015816)
0.0	0.0	GO:0010719	negative regulation of epithelial to mesenchymal transition(GO:0010719)
0.0	0.0	GO:0006907	pinocytosis(GO:0006907)
0.0	0.0	GO:0006556	S-adenosylmethionine biosynthetic process(GO:0006556)
0.0	0.2	GO:0006297	nucleotide-excision repair, DNA gap filling(GO:0006297)
0.0	0.0	GO:0006516	glycoprotein catabolic process(GO:0006516)
0.0	0.1	GO:0046689	response to mercury ion(GO:0046689)
0.0	0.1	GO:0033138	positive regulation of peptidyl-serine phosphorylation(GO:0033138)
0.0	0.2	GO:0006513	protein monoubiquitination(GO:0006513)
0.0	0.0	GO:0032733	positive regulation of interleukin-10 production(GO:0032733)
0.0	0.3	GO:0000245	spliceosomal complex assembly(GO:0000245)
0.0	0.0	GO:0032075	positive regulation of nuclease activity(GO:0032075)
0.0	0.1	GO:0060009	Sertoli cell development(GO:0060009)
0.0	0.0	GO:0071569	protein ufmylation(GO:0071569)
0.0	0.1	GO:0001867	complement activation, lectin pathway(GO:0001867)
0.0	0.0	GO:0045342	MHC class II biosynthetic process(GO:0045342)
0.0	0.0	GO:0042816	pyridoxine metabolic process(GO:0008614) pyridoxine biosynthetic process(GO:0008615) vitamin B6 metabolic process(GO:0042816) vitamin B6 biosynthetic process(GO:0042819)
0.0	0.0	GO:0090312	regulation of protein deacetylation(GO:0090311) positive regulation of protein deacetylation(GO:0090312)
0.0	0.1	GO:0031648	protein destabilization(GO:0031648)
0.0	0.2	GO:0035036	sperm-egg recognition(GO:0035036)
0.0	0.1	GO:0019673	GDP-mannose metabolic process(GO:0019673)
0.0	0.0	GO:0046952	ketone body catabolic process(GO:0046952)
0.0	0.0	GO:0042339	keratan sulfate metabolic process(GO:0042339)
0.0	0.1	GO:0016558	protein import into peroxisome matrix(GO:0016558)
0.0	0.1	GO:0045047	protein targeting to ER(GO:0045047) establishment of protein localization to endoplasmic reticulum(GO:0072599)
0.0	0.1	GO:0036296	response to increased oxygen levels(GO:0036296) response to hyperoxia(GO:0055093)
0.0	0.1	GO:0007080	mitotic metaphase plate congression(GO:0007080)
0.0	0.4	GO:0030521	androgen receptor signaling pathway(GO:0030521)
0.0	0.0	GO:0009648	photoperiodism(GO:0009648)
0.0	0.0	GO:0006106	fumarate metabolic process(GO:0006106)
0.0	0.0	GO:0051447	negative regulation of meiotic cell cycle(GO:0051447)
0.0	0.1	GO:0018106	peptidyl-histidine phosphorylation(GO:0018106)
0.0	0.2	GO:0006783	heme biosynthetic process(GO:0006783)
0.0	0.1	GO:0046627	negative regulation of insulin receptor signaling pathway(GO:0046627) negative regulation of cellular response to insulin stimulus(GO:1900077)
0.0	0.4	GO:0050434	positive regulation of viral transcription(GO:0050434)
0.0	0.2	GO:0043966	histone H3 acetylation(GO:0043966)
0.0	0.0	GO:1901419	regulation of response to alcohol(GO:1901419)
0.0	0.2	GO:0000188	inactivation of MAPK activity(GO:0000188)
0.0	0.0	GO:0072216	positive regulation of metanephros development(GO:0072216)
0.0	0.0	GO:0032717	negative regulation of interleukin-8 production(GO:0032717)
0.0	0.0	GO:0002864	hypersensitivity(GO:0002524) positive regulation of inflammatory response to antigenic stimulus(GO:0002863) regulation of acute inflammatory response to antigenic stimulus(GO:0002864) positive regulation of acute inflammatory response to antigenic stimulus(GO:0002866) regulation of hypersensitivity(GO:0002883) positive regulation of hypersensitivity(GO:0002885)
0.0	0.0	GO:0060231	mesenchymal to epithelial transition(GO:0060231)
0.0	0.1	GO:0030212	hyaluronan metabolic process(GO:0030212)
0.0	0.1	GO:0046655	folic acid metabolic process(GO:0046655)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.4	GO:0031235	intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.1	0.4	GO:0005827	polar microtubule(GO:0005827)
0.1	0.3	GO:0005736	DNA-directed RNA polymerase I complex(GO:0005736)
0.1	0.4	GO:0045179	apical cortex(GO:0045179)
0.1	0.3	GO:0031229	integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229) nuclear membrane part(GO:0044453)
0.1	0.3	GO:0005797	Golgi medial cisterna(GO:0005797)
0.1	0.2	GO:0042105	alpha-beta T cell receptor complex(GO:0042105)
0.1	0.3	GO:0031088	platelet dense granule membrane(GO:0031088)
0.0	0.3	GO:0044224	juxtaparanode region of axon(GO:0044224)
0.0	0.2	GO:0070695	FHF complex(GO:0070695)
0.0	0.1	GO:0042629	mast cell granule(GO:0042629)
0.0	0.5	GO:0001772	immunological synapse(GO:0001772)
0.0	0.6	GO:0005942	phosphatidylinositol 3-kinase complex(GO:0005942)
0.0	0.2	GO:0071778	obsolete WINAC complex(GO:0071778)
0.0	0.2	GO:0001931	uropod(GO:0001931) cell trailing edge(GO:0031254)
0.0	0.2	GO:0005663	DNA replication factor C complex(GO:0005663)
0.0	0.5	GO:0043209	myelin sheath(GO:0043209)
0.0	0.0	GO:0071062	alphav-beta3 integrin-vitronectin complex(GO:0071062)
0.0	0.0	GO:0034363	intermediate-density lipoprotein particle(GO:0034363)
0.0	0.2	GO:0001891	phagocytic cup(GO:0001891)
0.0	0.1	GO:0014731	spectrin-associated cytoskeleton(GO:0014731)
0.0	0.1	GO:0071438	invadopodium membrane(GO:0071438)
0.0	0.1	GO:0070022	transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.0	0.1	GO:0030895	apolipoprotein B mRNA editing enzyme complex(GO:0030895)
0.0	0.1	GO:0000300	obsolete peripheral to membrane of membrane fraction(GO:0000300)
0.0	0.1	GO:0033150	cytoskeletal calyx(GO:0033150)
0.0	0.1	GO:0000796	condensin complex(GO:0000796)
0.0	0.1	GO:0008540	proteasome regulatory particle, base subcomplex(GO:0008540)
0.0	0.3	GO:0010494	cytoplasmic stress granule(GO:0010494)
0.0	0.3	GO:0045120	pronucleus(GO:0045120)
0.0	0.2	GO:0000791	euchromatin(GO:0000791)
0.0	0.1	GO:0036454	insulin-like growth factor binding protein complex(GO:0016942) growth factor complex(GO:0036454)
0.0	0.3	GO:0030132	clathrin coat of coated pit(GO:0030132)
0.0	0.1	GO:0005750	mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
0.0	0.1	GO:0000124	SAGA complex(GO:0000124)
0.0	0.4	GO:0005892	acetylcholine-gated channel complex(GO:0005892)
0.0	0.1	GO:0043657	host(GO:0018995) host cell part(GO:0033643) host intracellular part(GO:0033646) intracellular region of host(GO:0043656) host cell(GO:0043657) other organism(GO:0044215) other organism cell(GO:0044216) other organism part(GO:0044217)
0.0	0.9	GO:0030175	filopodium(GO:0030175)
0.0	0.2	GO:0032279	asymmetric synapse(GO:0032279) neuron to neuron synapse(GO:0098984)
0.0	0.1	GO:0005721	pericentric heterochromatin(GO:0005721)
0.0	0.5	GO:0019005	SCF ubiquitin ligase complex(GO:0019005)
0.0	0.1	GO:0070775	H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.0	0.1	GO:0005896	interleukin-6 receptor complex(GO:0005896)
0.0	0.1	GO:0000445	THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.0	0.3	GO:0035631	CD40 receptor complex(GO:0035631)
0.0	0.2	GO:0032839	dendrite cytoplasm(GO:0032839)
0.0	0.1	GO:0005682	U5 snRNP(GO:0005682)
0.0	0.1	GO:0031371	ubiquitin conjugating enzyme complex(GO:0031371)
0.0	0.2	GO:0031105	septin complex(GO:0031105) septin cytoskeleton(GO:0032156)
0.0	0.1	GO:0005945	6-phosphofructokinase complex(GO:0005945)
0.0	0.2	GO:0061200	clathrin-sculpted gamma-aminobutyric acid transport vesicle(GO:0061200) clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane(GO:0061202)
0.0	0.7	GO:0005626	obsolete insoluble fraction(GO:0005626)
0.0	0.2	GO:0005861	troponin complex(GO:0005861)
0.0	0.1	GO:0031211	palmitoyltransferase complex(GO:0002178) serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211)
0.0	0.1	GO:0042627	chylomicron(GO:0042627)
0.0	0.2	GO:0016514	SWI/SNF complex(GO:0016514)
0.0	0.0	GO:0031932	TORC2 complex(GO:0031932)
0.0	0.2	GO:0008385	IkappaB kinase complex(GO:0008385)
0.0	0.2	GO:0005664	origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.0	0.2	GO:0042589	zymogen granule membrane(GO:0042589)
0.0	0.2	GO:0016585	obsolete chromatin remodeling complex(GO:0016585)
0.0	0.1	GO:0000942	condensed nuclear chromosome outer kinetochore(GO:0000942)
0.0	0.1	GO:0045334	clathrin-coated endocytic vesicle(GO:0045334)
0.0	0.1	GO:0005658	alpha DNA polymerase:primase complex(GO:0005658)
0.0	0.3	GO:0000123	histone acetyltransferase complex(GO:0000123) protein acetyltransferase complex(GO:0031248) acetyltransferase complex(GO:1902493)
0.0	0.1	GO:0034045	pre-autophagosomal structure membrane(GO:0034045)
0.0	0.2	GO:0000242	pericentriolar material(GO:0000242)
0.0	0.1	GO:0042765	GPI-anchor transamidase complex(GO:0042765)
0.0	0.1	GO:0072669	tRNA-splicing ligase complex(GO:0072669)
0.0	0.0	GO:0070552	BRISC complex(GO:0070552)
0.0	0.1	GO:0000164	protein phosphatase type 1 complex(GO:0000164)
0.0	0.2	GO:0034362	low-density lipoprotein particle(GO:0034362)
0.0	0.1	GO:0042583	chromaffin granule(GO:0042583) chromaffin granule membrane(GO:0042584)
0.0	0.1	GO:0016471	vacuolar proton-transporting V-type ATPase complex(GO:0016471)
0.0	0.1	GO:0000138	Golgi trans cisterna(GO:0000138)
0.0	0.2	GO:0005665	DNA-directed RNA polymerase II, core complex(GO:0005665)
0.0	0.7	GO:0005778	peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.0	0.2	GO:0035267	NuA4 histone acetyltransferase complex(GO:0035267)
0.0	0.0	GO:0030008	TRAPP complex(GO:0030008)
0.0	0.0	GO:0031205	endoplasmic reticulum Sec complex(GO:0031205)
0.0	0.2	GO:0030914	STAGA complex(GO:0030914)
0.0	0.1	GO:0070822	Sin3 complex(GO:0016580) Sin3-type complex(GO:0070822)
0.0	0.1	GO:0030904	retromer complex(GO:0030904)
0.0	0.0	GO:0032009	early phagosome(GO:0032009)
0.0	0.2	GO:0008250	oligosaccharyltransferase complex(GO:0008250)
0.0	0.2	GO:0016235	aggresome(GO:0016235)
0.0	0.1	GO:0008290	F-actin capping protein complex(GO:0008290)
0.0	0.0	GO:0071565	nBAF complex(GO:0071565)
0.0	0.1	GO:0005697	telomerase holoenzyme complex(GO:0005697)
0.0	0.1	GO:0031080	nuclear pore outer ring(GO:0031080)
0.0	0.1	GO:0000782	telomere cap complex(GO:0000782) nuclear telomere cap complex(GO:0000783)
0.0	0.0	GO:0072379	BAT3 complex(GO:0071818) ER membrane insertion complex(GO:0072379)
0.0	0.1	GO:0016281	eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0	0.0	GO:0033553	rDNA heterochromatin(GO:0033553)
0.0	0.1	GO:0017146	NMDA selective glutamate receptor complex(GO:0017146)
0.0	0.1	GO:0042582	primary lysosome(GO:0005766) azurophil granule(GO:0042582)
0.0	0.0	GO:0070688	MLL5-L complex(GO:0070688)
0.0	1.6	GO:0009897	external side of plasma membrane(GO:0009897)
0.0	0.0	GO:0071001	U4/U6 snRNP(GO:0071001)
0.0	2.9	GO:0005667	transcription factor complex(GO:0005667)
0.0	0.1	GO:0001741	XY body(GO:0001741)
0.0	0.0	GO:0005594	collagen type IX trimer(GO:0005594)
0.0	0.0	GO:0042825	MHC class I peptide loading complex(GO:0042824) TAP complex(GO:0042825)
0.0	0.1	GO:0070531	BRCA1-A complex(GO:0070531)
0.0	0.8	GO:0060076	excitatory synapse(GO:0060076)
0.0	0.3	GO:0000932	cytoplasmic mRNA processing body(GO:0000932)
0.0	0.1	GO:0030126	COPI vesicle coat(GO:0030126)
0.0	0.1	GO:0072357	PTW/PP1 phosphatase complex(GO:0072357)
0.0	0.3	GO:0043204	perikaryon(GO:0043204)
0.0	0.0	GO:0090544	BAF-type complex(GO:0090544)
0.0	0.4	GO:0042645	mitochondrial nucleoid(GO:0042645)
0.0	0.5	GO:0030176	integral component of endoplasmic reticulum membrane(GO:0030176)
0.0	0.0	GO:0005787	signal peptidase complex(GO:0005787)
0.0	0.1	GO:0032589	neuron projection membrane(GO:0032589)
0.0	0.1	GO:0033179	proton-transporting V-type ATPase, V0 domain(GO:0033179)
0.0	0.2	GO:0080008	Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.0	0.1	GO:0034361	very-low-density lipoprotein particle(GO:0034361) triglyceride-rich lipoprotein particle(GO:0034385)
0.0	0.5	GO:0016605	PML body(GO:0016605)
0.0	0.1	GO:0008278	cohesin complex(GO:0008278)
0.0	0.4	GO:0099501	synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.0	0.0	GO:0030288	outer membrane-bounded periplasmic space(GO:0030288) periplasmic space(GO:0042597)
0.0	0.1	GO:0005662	DNA replication factor A complex(GO:0005662)
0.0	0.1	GO:0019908	nuclear cyclin-dependent protein kinase holoenzyme complex(GO:0019908)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.5	GO:0043522	leucine zipper domain binding(GO:0043522)
0.1	0.3	GO:0031628	opioid receptor binding(GO:0031628)
0.1	0.3	GO:0003726	double-stranded RNA adenosine deaminase activity(GO:0003726)
0.1	0.4	GO:0016004	phospholipase activator activity(GO:0016004)
0.1	0.7	GO:0030332	cyclin binding(GO:0030332)
0.1	0.3	GO:0017128	phospholipid scramblase activity(GO:0017128)
0.1	0.3	GO:0046935	1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.1	0.3	GO:0030284	estrogen receptor activity(GO:0030284)
0.1	0.2	GO:0033691	sialic acid binding(GO:0033691)
0.1	0.5	GO:0001609	G-protein coupled adenosine receptor activity(GO:0001609)
0.1	0.2	GO:0042156	obsolete zinc-mediated transcriptional activator activity(GO:0042156)
0.1	0.2	GO:0004311	farnesyltranstransferase activity(GO:0004311)
0.1	0.2	GO:0004911	interleukin-2 receptor activity(GO:0004911)
0.1	0.6	GO:0005522	profilin binding(GO:0005522)
0.1	0.2	GO:0016309	1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
0.1	0.4	GO:0016494	C-X-C chemokine receptor activity(GO:0016494)
0.1	0.2	GO:0008454	alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.1	0.8	GO:0005031	tumor necrosis factor-activated receptor activity(GO:0005031)
0.1	0.2	GO:0030368	interleukin-17 receptor activity(GO:0030368)
0.1	0.6	GO:0016493	C-C chemokine receptor activity(GO:0016493)
0.1	0.1	GO:0050510	N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity(GO:0050510)
0.1	0.2	GO:0035184	histone threonine kinase activity(GO:0035184)
0.1	0.2	GO:0004706	JUN kinase kinase kinase activity(GO:0004706)
0.1	0.3	GO:0005143	interleukin-12 receptor binding(GO:0005143)
0.1	0.1	GO:0043008	ATP-dependent protein binding(GO:0043008)
0.1	0.3	GO:0008020	G-protein coupled photoreceptor activity(GO:0008020)
0.0	0.8	GO:0004115	3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0	0.1	GO:0046975	histone methyltransferase activity (H3-K36 specific)(GO:0046975)
0.0	0.1	GO:0031014	troponin T binding(GO:0031014)
0.0	0.2	GO:0004694	eukaryotic translation initiation factor 2alpha kinase activity(GO:0004694)
0.0	0.2	GO:0052813	phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) phosphatidylinositol bisphosphate kinase activity(GO:0052813)
0.0	0.2	GO:0033170	DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.0	0.1	GO:0001601	peptide YY receptor activity(GO:0001601)
0.0	0.5	GO:0099604	calcium-release channel activity(GO:0015278) ligand-gated calcium channel activity(GO:0099604)
0.0	0.4	GO:0015271	outward rectifier potassium channel activity(GO:0015271)
0.0	0.2	GO:0034452	dynactin binding(GO:0034452)
0.0	0.6	GO:0005246	calcium channel regulator activity(GO:0005246)
0.0	0.1	GO:0016748	succinyltransferase activity(GO:0016748)
0.0	0.1	GO:0030172	troponin C binding(GO:0030172)
0.0	0.1	GO:0043533	inositol 1,3,4,5 tetrakisphosphate binding(GO:0043533)
0.0	0.1	GO:0042608	T cell receptor binding(GO:0042608)
0.0	0.4	GO:0070411	I-SMAD binding(GO:0070411)
0.0	0.2	GO:0051864	histone demethylase activity (H3-K36 specific)(GO:0051864)
0.0	0.2	GO:0003886	DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.0	0.2	GO:0005078	MAP-kinase scaffold activity(GO:0005078)
0.0	0.2	GO:0015379	potassium:chloride symporter activity(GO:0015379)
0.0	0.1	GO:0032454	histone demethylase activity (H3-K9 specific)(GO:0032454)
0.0	0.2	GO:0055103	ligase regulator activity(GO:0055103) ubiquitin-protein transferase regulator activity(GO:0055106)
0.0	0.2	GO:0001637	G-protein coupled chemoattractant receptor activity(GO:0001637) chemokine receptor activity(GO:0004950)
0.0	0.3	GO:0030676	Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0	0.6	GO:0015026	coreceptor activity(GO:0015026)
0.0	0.1	GO:0004517	nitric-oxide synthase activity(GO:0004517)
0.0	0.4	GO:0030276	clathrin binding(GO:0030276)
0.0	0.5	GO:0005095	GTPase inhibitor activity(GO:0005095)
0.0	0.3	GO:0004017	adenylate kinase activity(GO:0004017)
0.0	0.1	GO:0070653	high-density lipoprotein particle receptor binding(GO:0070653)
0.0	0.2	GO:0001727	lipid kinase activity(GO:0001727)
0.0	0.1	GO:0005432	calcium:sodium antiporter activity(GO:0005432)
0.0	0.5	GO:0004707	MAP kinase activity(GO:0004707)
0.0	0.1	GO:0047238	glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity(GO:0047238)
0.0	0.1	GO:0048018	receptor agonist activity(GO:0048018)
0.0	0.1	GO:0043024	ribosomal small subunit binding(GO:0043024)
0.0	0.2	GO:0070567	cytidylyltransferase activity(GO:0070567)
0.0	0.1	GO:0016802	adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.0	0.1	GO:0010521	telomerase inhibitor activity(GO:0010521)
0.0	0.2	GO:0016308	1-phosphatidylinositol-4-phosphate 5-kinase activity(GO:0016308)
0.0	0.5	GO:0043014	alpha-tubulin binding(GO:0043014)
0.0	0.1	GO:0070548	L-glutamine aminotransferase activity(GO:0070548)
0.0	0.1	GO:0034648	histone demethylase activity (H3-K4 specific)(GO:0032453) histone demethylase activity (H3-dimethyl-K4 specific)(GO:0034648)
0.0	0.2	GO:0008467	[heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.0	0.1	GO:0016907	G-protein coupled acetylcholine receptor activity(GO:0016907)
0.0	1.5	GO:0008301	DNA binding, bending(GO:0008301)
0.0	0.1	GO:0008821	crossover junction endodeoxyribonuclease activity(GO:0008821)
0.0	0.1	GO:0003829	beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity(GO:0003829)
0.0	0.2	GO:0005375	copper ion transmembrane transporter activity(GO:0005375)
0.0	0.2	GO:0015288	porin activity(GO:0015288)
0.0	0.1	GO:0042392	sphingosine-1-phosphate phosphatase activity(GO:0042392)
0.0	0.4	GO:0004889	acetylcholine-activated cation-selective channel activity(GO:0004889)
0.0	0.1	GO:0070215	obsolete MDM2 binding(GO:0070215)
0.0	0.1	GO:0043560	insulin receptor substrate binding(GO:0043560)
0.0	0.1	GO:0004095	carnitine O-palmitoyltransferase activity(GO:0004095) O-palmitoyltransferase activity(GO:0016416)
0.0	0.3	GO:0043425	bHLH transcription factor binding(GO:0043425)
0.0	0.1	GO:0003720	telomerase activity(GO:0003720) RNA-directed DNA polymerase activity(GO:0003964)
0.0	0.2	GO:0042288	MHC class I protein binding(GO:0042288)
0.0	0.1	GO:0016312	inositol bisphosphate phosphatase activity(GO:0016312)
0.0	0.1	GO:0004169	dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.0	0.2	GO:0070087	chromo shadow domain binding(GO:0070087)
0.0	0.0	GO:0060230	lipoprotein lipase activator activity(GO:0060230)
0.0	0.1	GO:0005113	patched binding(GO:0005113)
0.0	0.1	GO:0004974	leukotriene receptor activity(GO:0004974)
0.0	0.9	GO:0004715	non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.0	0.1	GO:0070053	thrombospondin receptor activity(GO:0070053)
0.0	0.1	GO:0005094	Rho GDP-dissociation inhibitor activity(GO:0005094)
0.0	0.1	GO:0004814	arginine-tRNA ligase activity(GO:0004814)
0.0	0.5	GO:0005164	tumor necrosis factor receptor binding(GO:0005164)
0.0	0.1	GO:0016286	small conductance calcium-activated potassium channel activity(GO:0016286)
0.0	0.2	GO:0043395	heparan sulfate proteoglycan binding(GO:0043395)
0.0	0.1	GO:0003986	acetyl-CoA hydrolase activity(GO:0003986)
0.0	0.2	GO:0016888	endodeoxyribonuclease activity, producing 5'-phosphomonoesters(GO:0016888)
0.0	0.0	GO:0070492	oligosaccharide binding(GO:0070492)
0.0	0.7	GO:0016831	carboxy-lyase activity(GO:0016831)
0.0	0.0	GO:0004127	cytidylate kinase activity(GO:0004127)
0.0	0.1	GO:0070326	very-low-density lipoprotein particle receptor binding(GO:0070326)
0.0	0.0	GO:0016531	copper chaperone activity(GO:0016531)
0.0	0.1	GO:0003691	double-stranded telomeric DNA binding(GO:0003691)
0.0	0.1	GO:0008157	protein phosphatase 1 binding(GO:0008157)
0.0	0.4	GO:0005086	ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0	0.1	GO:0031624	ubiquitin conjugating enzyme binding(GO:0031624) ubiquitin-like protein conjugating enzyme binding(GO:0044390)
0.0	0.1	GO:0043175	RNA polymerase core enzyme binding(GO:0043175)
0.0	0.0	GO:0005035	death receptor activity(GO:0005035)
0.0	0.1	GO:0003872	6-phosphofructokinase activity(GO:0003872)
0.0	0.2	GO:0017025	TBP-class protein binding(GO:0017025)
0.0	0.2	GO:0051766	inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440) inositol trisphosphate kinase activity(GO:0051766)
0.0	0.1	GO:0005346	purine ribonucleotide transmembrane transporter activity(GO:0005346)
0.0	0.2	GO:0017127	cholesterol transporter activity(GO:0017127)
0.0	0.1	GO:0015333	peptide:proton symporter activity(GO:0015333) proton-dependent peptide secondary active transmembrane transporter activity(GO:0022897)
0.0	0.1	GO:0004476	mannose-6-phosphate isomerase activity(GO:0004476)
0.0	0.1	GO:0004500	dopamine beta-monooxygenase activity(GO:0004500)
0.0	0.8	GO:0061733	peptide-lysine-N-acetyltransferase activity(GO:0061733)
0.0	0.2	GO:0030371	translation repressor activity(GO:0030371)
0.0	0.2	GO:0004708	MAP kinase kinase activity(GO:0004708)
0.0	0.1	GO:0070579	methylcytosine dioxygenase activity(GO:0070579)
0.0	0.0	GO:0031013	troponin I binding(GO:0031013)
0.0	0.1	GO:0035004	1-phosphatidylinositol-3-kinase activity(GO:0016303) phosphatidylinositol 3-kinase activity(GO:0035004)
0.0	0.1	GO:0051400	BH domain binding(GO:0051400)
0.0	0.1	GO:0005138	interleukin-6 receptor binding(GO:0005138)
0.0	0.1	GO:0001517	N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517)
0.0	0.1	GO:0000064	L-ornithine transmembrane transporter activity(GO:0000064)
0.0	0.1	GO:0004719	protein-L-isoaspartate (D-aspartate) O-methyltransferase activity(GO:0004719)
0.0	0.2	GO:0004143	diacylglycerol kinase activity(GO:0004143)
0.0	0.1	GO:0008296	3'-5'-exodeoxyribonuclease activity(GO:0008296)
0.0	0.1	GO:0019863	IgE binding(GO:0019863)
0.0	0.1	GO:0004591	oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591)
0.0	0.1	GO:0015165	pyrimidine nucleotide-sugar transmembrane transporter activity(GO:0015165)
0.0	0.1	GO:0015355	secondary active monocarboxylate transmembrane transporter activity(GO:0015355)
0.0	0.1	GO:0004301	epoxide hydrolase activity(GO:0004301)
0.0	0.1	GO:0070097	delta-catenin binding(GO:0070097)
0.0	0.1	GO:0016165	linoleate 13S-lipoxygenase activity(GO:0016165)
0.0	0.0	GO:0042289	MHC class II protein binding(GO:0042289)
0.0	0.1	GO:0004775	succinate-CoA ligase (ADP-forming) activity(GO:0004775)
0.0	0.0	GO:0043398	HLH domain binding(GO:0043398)
0.0	0.7	GO:0003899	DNA-directed RNA polymerase activity(GO:0003899) RNA polymerase activity(GO:0034062)
0.0	0.1	GO:0052650	NADP-retinol dehydrogenase activity(GO:0052650)
0.0	0.2	GO:0004579	dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.0	0.3	GO:0005001	transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.0	0.1	GO:0008131	primary amine oxidase activity(GO:0008131)
0.0	0.1	GO:0004740	pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.0	0.1	GO:0008321	Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.0	0.1	GO:0003923	GPI-anchor transamidase activity(GO:0003923)
0.0	0.1	GO:0004865	protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.0	0.1	GO:0004704	NF-kappaB-inducing kinase activity(GO:0004704)
0.0	0.2	GO:0046965	retinoid X receptor binding(GO:0046965)
0.0	0.1	GO:0042808	obsolete neuronal Cdc2-like kinase binding(GO:0042808)
0.0	0.1	GO:0009881	photoreceptor activity(GO:0009881)
0.0	0.1	GO:0017162	aryl hydrocarbon receptor binding(GO:0017162)
0.0	0.2	GO:0004697	protein kinase C activity(GO:0004697)
0.0	0.1	GO:0008332	low voltage-gated calcium channel activity(GO:0008332)
0.0	0.1	GO:0008889	glycerophosphodiester phosphodiesterase activity(GO:0008889)
0.0	0.1	GO:0008195	phosphatidate phosphatase activity(GO:0008195)
0.0	0.1	GO:0004459	L-lactate dehydrogenase activity(GO:0004459)
0.0	0.2	GO:0035251	UDP-glucosyltransferase activity(GO:0035251)
0.0	0.1	GO:0033613	activating transcription factor binding(GO:0033613)
0.0	0.0	GO:0048256	flap endonuclease activity(GO:0048256)
0.0	0.1	GO:0004767	sphingomyelin phosphodiesterase activity(GO:0004767)
0.0	0.0	GO:0004505	phenylalanine 4-monooxygenase activity(GO:0004505)
0.0	0.2	GO:0008191	metalloendopeptidase inhibitor activity(GO:0008191)
0.0	0.0	GO:0031849	olfactory receptor binding(GO:0031849)
0.0	0.1	GO:0008649	rRNA methyltransferase activity(GO:0008649)
0.0	0.0	GO:0015464	acetylcholine receptor activity(GO:0015464)
0.0	0.0	GO:0005049	nuclear export signal receptor activity(GO:0005049)
0.0	0.0	GO:0004774	succinate-CoA ligase activity(GO:0004774)
0.0	0.2	GO:0005487	nucleocytoplasmic transporter activity(GO:0005487)
0.0	0.0	GO:0016895	exodeoxyribonuclease activity(GO:0004529) exodeoxyribonuclease activity, producing 5'-phosphomonoesters(GO:0016895)
0.0	0.1	GO:0004663	Rab geranylgeranyltransferase activity(GO:0004663)
0.0	0.1	GO:0004972	NMDA glutamate receptor activity(GO:0004972)
0.0	0.0	GO:0008035	high-density lipoprotein particle binding(GO:0008035)
0.0	0.1	GO:0015347	sodium-independent organic anion transmembrane transporter activity(GO:0015347)
0.0	0.1	GO:0016565	obsolete general transcriptional repressor activity(GO:0016565)
0.0	0.0	GO:0003985	acetyl-CoA C-acetyltransferase activity(GO:0003985)
0.0	0.0	GO:0098599	palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.0	0.0	GO:0030899	calcium-dependent ATPase activity(GO:0030899)
0.0	0.1	GO:0008429	phosphatidylethanolamine binding(GO:0008429)
0.0	0.1	GO:0030274	LIM domain binding(GO:0030274)
0.0	0.2	GO:0003711	obsolete transcription elongation regulator activity(GO:0003711)
0.0	0.1	GO:0001671	ATPase activator activity(GO:0001671)
0.0	0.0	GO:0004477	methenyltetrahydrofolate cyclohydrolase activity(GO:0004477)
0.0	0.1	GO:0050750	low-density lipoprotein particle receptor binding(GO:0050750)
0.0	0.1	GO:0070016	armadillo repeat domain binding(GO:0070016)
0.0	0.1	GO:0004331	fructose-2,6-bisphosphate 2-phosphatase activity(GO:0004331)
0.0	0.0	GO:0043141	ATP-dependent 5'-3' DNA helicase activity(GO:0043141)
0.0	0.2	GO:0001540	beta-amyloid binding(GO:0001540)
0.0	0.2	GO:0048365	Rac GTPase binding(GO:0048365)
0.0	0.1	GO:0015924	mannosyl-oligosaccharide mannosidase activity(GO:0015924)
0.0	0.0	GO:0017060	3-galactosyl-N-acetylglucosaminide 4-alpha-L-fucosyltransferase activity(GO:0017060)
0.0	0.1	GO:0016857	racemase and epimerase activity, acting on carbohydrates and derivatives(GO:0016857)
0.0	0.0	GO:0015211	purine nucleoside transmembrane transporter activity(GO:0015211)
0.0	0.1	GO:0031781	melanocortin receptor binding(GO:0031779) type 3 melanocortin receptor binding(GO:0031781) type 4 melanocortin receptor binding(GO:0031782)
0.0	0.0	GO:0003706	obsolete ligand-regulated transcription factor activity(GO:0003706)
0.0	0.0	GO:0004875	complement receptor activity(GO:0004875)
0.0	0.5	GO:0098531	RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding(GO:0004879) transcription factor activity, direct ligand regulated sequence-specific DNA binding(GO:0098531)
0.0	0.0	GO:0003910	DNA ligase activity(GO:0003909) DNA ligase (ATP) activity(GO:0003910)
0.0	0.1	GO:0004596	peptide alpha-N-acetyltransferase activity(GO:0004596)
0.0	0.2	GO:0042809	vitamin D receptor binding(GO:0042809)
0.0	0.1	GO:0070410	co-SMAD binding(GO:0070410)
0.0	0.0	GO:0030343	vitamin D3 25-hydroxylase activity(GO:0030343) vitamin D 25-hydroxylase activity(GO:0070643)
0.0	0.1	GO:0016208	AMP binding(GO:0016208)
0.0	0.1	GO:0015057	thrombin receptor activity(GO:0015057)
0.0	0.1	GO:0046625	sphingolipid binding(GO:0046625)
0.0	0.2	GO:0000175	3'-5'-exoribonuclease activity(GO:0000175)
0.0	0.0	GO:0034237	protein kinase A regulatory subunit binding(GO:0034237)
0.0	0.1	GO:0046974	histone methyltransferase activity (H3-K9 specific)(GO:0046974)
0.0	0.1	GO:0017040	ceramidase activity(GO:0017040)
0.0	0.1	GO:0043539	protein serine/threonine kinase activator activity(GO:0043539)
0.0	0.0	GO:0034236	protein kinase A catalytic subunit binding(GO:0034236)
0.0	0.1	GO:0004616	phosphogluconate dehydrogenase (decarboxylating) activity(GO:0004616)
0.0	0.1	GO:0030159	receptor signaling complex scaffold activity(GO:0030159)
0.0	0.4	GO:0008094	DNA-dependent ATPase activity(GO:0008094)
0.0	0.0	GO:0015349	thyroid hormone transmembrane transporter activity(GO:0015349)
0.0	0.1	GO:0008353	RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.0	0.5	GO:0003678	DNA helicase activity(GO:0003678)
0.0	0.1	GO:0004000	adenosine deaminase activity(GO:0004000)
0.0	0.1	GO:0034593	phosphatidylinositol bisphosphate phosphatase activity(GO:0034593)
0.0	0.1	GO:0030346	protein phosphatase 2B binding(GO:0030346)
0.0	0.0	GO:0030976	thiamine pyrophosphate binding(GO:0030976)
0.0	0.0	GO:0001591	dopamine neurotransmitter receptor activity, coupled via Gi/Go(GO:0001591)
0.0	0.0	GO:0003831	beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity(GO:0003831)
0.0	0.2	GO:0043027	cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.0	0.2	GO:0016638	oxidoreductase activity, acting on the CH-NH2 group of donors(GO:0016638)
0.0	0.0	GO:0004828	serine-tRNA ligase activity(GO:0004828)
0.0	1.2	GO:0017124	SH3 domain binding(GO:0017124)
0.0	0.0	GO:0042975	peroxisome proliferator activated receptor binding(GO:0042975)
0.0	0.0	GO:0005092	GDP-dissociation inhibitor activity(GO:0005092)
0.0	0.2	GO:0003995	acyl-CoA dehydrogenase activity(GO:0003995)
0.0	0.1	GO:0003688	DNA replication origin binding(GO:0003688)
0.0	0.1	GO:0005159	insulin-like growth factor receptor binding(GO:0005159)
0.0	0.1	GO:0008553	hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.0	0.1	GO:0043548	phosphatidylinositol 3-kinase binding(GO:0043548)
0.0	0.1	GO:0005007	fibroblast growth factor-activated receptor activity(GO:0005007)
0.0	0.1	GO:0015643	toxic substance binding(GO:0015643)
0.0	0.0	GO:0008327	methyl-CpG binding(GO:0008327)
0.0	1.2	GO:0003702	obsolete RNA polymerase II transcription factor activity(GO:0003702)
0.0	0.2	GO:0005248	voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
0.0	0.0	GO:0099528	G-protein coupled neurotransmitter receptor activity(GO:0099528)
0.0	0.0	GO:0016160	alpha-amylase activity(GO:0004556) amylase activity(GO:0016160)
0.0	0.0	GO:0004339	glucan 1,4-alpha-glucosidase activity(GO:0004339)
0.0	0.0	GO:0070412	R-SMAD binding(GO:0070412)
0.0	0.0	GO:0019238	cyclohydrolase activity(GO:0019238)
0.0	0.1	GO:0003840	gamma-glutamyltransferase activity(GO:0003840)
0.0	0.0	GO:0034187	obsolete apolipoprotein E binding(GO:0034187)
0.0	0.1	GO:0004726	non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.0	0.2	GO:0005247	voltage-gated chloride channel activity(GO:0005247)
0.0	0.0	GO:0035241	protein-arginine omega-N monomethyltransferase activity(GO:0035241)
0.0	0.0	GO:0015168	glycerol transmembrane transporter activity(GO:0015168)
0.0	0.1	GO:0016846	carbon-sulfur lyase activity(GO:0016846)
0.0	0.1	GO:0050811	GABA receptor binding(GO:0050811)
0.0	0.1	GO:0008408	3'-5' exonuclease activity(GO:0008408)
0.0	0.0	GO:0004957	prostaglandin E receptor activity(GO:0004957)
0.0	0.0	GO:0045569	TRAIL binding(GO:0045569)
0.0	0.0	GO:0015184	L-cystine transmembrane transporter activity(GO:0015184)
0.0	0.1	GO:0004994	somatostatin receptor activity(GO:0004994)
0.0	0.0	GO:0004465	lipoprotein lipase activity(GO:0004465)
0.0	0.1	GO:0015385	sodium:proton antiporter activity(GO:0015385)
0.0	0.1	GO:0055056	D-glucose transmembrane transporter activity(GO:0055056)
0.0	0.0	GO:0061731	ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.1	PID PI3KCI AKT PATHWAY	Class I PI3K signaling events mediated by Akt
0.1	1.8	PID IL12 STAT4 PATHWAY	IL12 signaling mediated by STAT4
0.1	0.9	SA MMP CYTOKINE CONNECTION	Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0	1.4	PID EPHRINB REV PATHWAY	Ephrin B reverse signaling
0.0	0.7	SA PTEN PATHWAY	PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.0	0.3	ST IL 13 PATHWAY	Interleukin 13 (IL-13) Pathway
0.0	0.7	PID FAS PATHWAY	FAS (CD95) signaling pathway
0.0	0.3	PID BETA CATENIN DEG PATHWAY	Degradation of beta catenin
0.0	1.5	PID CD8 TCR PATHWAY	TCR signaling in naïve CD8+ T cells
0.0	0.8	PID WNT CANONICAL PATHWAY	Canonical Wnt signaling pathway
0.0	0.1	PID TCR RAS PATHWAY	Ras signaling in the CD4+ TCR pathway
0.0	0.3	SA FAS SIGNALING	The TNF-type receptor Fas induces apoptosis on ligand binding.
0.0	0.9	PID ERBB1 INTERNALIZATION PATHWAY	Internalization of ErbB1
0.0	1.0	PID PI3KCI PATHWAY	Class I PI3K signaling events
0.0	0.0	PID ARF6 DOWNSTREAM PATHWAY	Arf6 downstream pathway
0.0	0.0	PID CXCR3 PATHWAY	CXCR3-mediated signaling events
0.0	0.4	PID IL27 PATHWAY	IL27-mediated signaling events
0.0	0.3	PID P38 GAMMA DELTA PATHWAY	Signaling mediated by p38-gamma and p38-delta
0.0	0.1	ST STAT3 PATHWAY	STAT3 Pathway
0.0	0.7	SIG INSULIN RECEPTOR PATHWAY IN CARDIAC MYOCYTES	Genes related to the insulin receptor pathway
0.0	1.2	PID IL4 2PATHWAY	IL4-mediated signaling events
0.0	0.6	PID MYC PATHWAY	C-MYC pathway
0.0	0.1	PID IL2 PI3K PATHWAY	IL2 signaling events mediated by PI3K
0.0	0.3	PID THROMBIN PAR4 PATHWAY	PAR4-mediated thrombin signaling events
0.0	0.6	PID NFAT 3PATHWAY	Role of Calcineurin-dependent NFAT signaling in lymphocytes
0.0	0.4	PID IL12 2PATHWAY	IL12-mediated signaling events
0.0	0.2	PID P38 MK2 PATHWAY	p38 signaling mediated by MAPKAP kinases
0.0	0.2	PID TCR CALCIUM PATHWAY	Calcium signaling in the CD4+ TCR pathway
0.0	0.7	PID ECADHERIN STABILIZATION PATHWAY	Stabilization and expansion of the E-cadherin adherens junction
0.0	0.3	PID LIS1 PATHWAY	Lissencephaly gene (LIS1) in neuronal migration and development
0.0	0.2	PID CIRCADIAN PATHWAY	Circadian rhythm pathway
0.0	0.1	PID CXCR4 PATHWAY	CXCR4-mediated signaling events
0.0	0.4	PID FCER1 PATHWAY	Fc-epsilon receptor I signaling in mast cells
0.0	0.1	ST TYPE I INTERFERON PATHWAY	Type I Interferon (alpha/beta IFN) Pathway
0.0	0.3	PID REELIN PATHWAY	Reelin signaling pathway
0.0	0.1	SIG BCR SIGNALING PATHWAY	Members of the BCR signaling pathway
0.0	1.1	PID SMAD2 3NUCLEAR PATHWAY	Regulation of nuclear SMAD2/3 signaling
0.0	0.1	ST PAC1 RECEPTOR PATHWAY	PAC1 Receptor Pathway
0.0	0.0	PID S1P S1P1 PATHWAY	S1P1 pathway
0.0	0.1	PID THROMBIN PAR1 PATHWAY	PAR1-mediated thrombin signaling events
0.0	0.2	SIG PIP3 SIGNALING IN B LYMPHOCYTES	Genes related to PIP3 signaling in B lymphocytes
0.0	0.2	PID ARF6 PATHWAY	Arf6 signaling events
0.0	0.2	PID ERBB2 ERBB3 PATHWAY	ErbB2/ErbB3 signaling events
0.0	0.6	PID TELOMERASE PATHWAY	Regulation of Telomerase
0.0	0.4	PID TNF PATHWAY	TNF receptor signaling pathway
0.0	0.6	PID BETA CATENIN NUC PATHWAY	Regulation of nuclear beta catenin signaling and target gene transcription
0.0	0.0	PID SYNDECAN 1 PATHWAY	Syndecan-1-mediated signaling events
0.0	0.4	PID CDC42 REG PATHWAY	Regulation of CDC42 activity
0.0	0.1	PID TCR PATHWAY	TCR signaling in naïve CD4+ T cells
0.0	0.1	PID TRAIL PATHWAY	TRAIL signaling pathway
0.0	0.6	PID FANCONI PATHWAY	Fanconi anemia pathway
0.0	0.2	SIG CD40PATHWAYMAP	Genes related to CD40 signaling
0.0	0.2	ST MYOCYTE AD PATHWAY	Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.0	0.2	PID ER NONGENOMIC PATHWAY	Plasma membrane estrogen receptor signaling
0.0	0.2	PID NFAT TFPATHWAY	Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0	0.1	PID P38 ALPHA BETA PATHWAY	Regulation of p38-alpha and p38-beta
0.0	0.0	PID S1P S1P4 PATHWAY	S1P4 pathway
0.0	0.0	PID IL5 PATHWAY	IL5-mediated signaling events
0.0	0.1	PID FRA PATHWAY	Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0	0.1	PID ATF2 PATHWAY	ATF-2 transcription factor network
0.0	0.4	PID AR TF PATHWAY	Regulation of Androgen receptor activity
0.0	0.3	PID TGFBR PATHWAY	TGF-beta receptor signaling
0.0	0.2	PID HES HEY PATHWAY	Notch-mediated HES/HEY network
0.0	0.1	PID BCR 5PATHWAY	BCR signaling pathway
0.0	0.2	PID HEDGEHOG GLI PATHWAY	Hedgehog signaling events mediated by Gli proteins
0.0	0.2	PID CD8 TCR DOWNSTREAM PATHWAY	Downstream signaling in naïve CD8+ T cells

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	1.2	REACTOME CD28 DEPENDENT VAV1 PATHWAY	Genes involved in CD28 dependent Vav1 pathway
0.1	0.3	REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS	Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.1	0.1	REACTOME REGULATION OF INSULIN SECRETION	Genes involved in Regulation of Insulin Secretion
0.1	0.1	REACTOME DOWNSTREAM TCR SIGNALING	Genes involved in Downstream TCR signaling
0.1	0.6	REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS	Genes involved in Signal regulatory protein (SIRP) family interactions
0.1	0.2	REACTOME BINDING AND ENTRY OF HIV VIRION	Genes involved in Binding and entry of HIV virion
0.0	1.2	REACTOME IL RECEPTOR SHC SIGNALING	Genes involved in Interleukin receptor SHC signaling
0.0	0.6	REACTOME P38MAPK EVENTS	Genes involved in p38MAPK events
0.0	0.4	REACTOME ROLE OF DCC IN REGULATING APOPTOSIS	Genes involved in Role of DCC in regulating apoptosis
0.0	0.9	REACTOME GENERATION OF SECOND MESSENGER MOLECULES	Genes involved in Generation of second messenger molecules
0.0	0.9	REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE	Genes involved in Sema4D induced cell migration and growth-cone collapse
0.0	0.2	REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX UPON TLR7 8 OR 9 STIMULATION	Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
0.0	0.7	REACTOME N GLYCAN ANTENNAE ELONGATION IN THE MEDIAL TRANS GOLGI	Genes involved in N-glycan antennae elongation in the medial/trans-Golgi
0.0	0.0	REACTOME AUTODEGRADATION OF THE E3 UBIQUITIN LIGASE COP1	Genes involved in Autodegradation of the E3 ubiquitin ligase COP1
0.0	0.6	REACTOME RNA POL III CHAIN ELONGATION	Genes involved in RNA Polymerase III Chain Elongation
0.0	0.1	REACTOME ENDOSOMAL VACUOLAR PATHWAY	Genes involved in Endosomal/Vacuolar pathway
0.0	0.8	REACTOME RORA ACTIVATES CIRCADIAN EXPRESSION	Genes involved in RORA Activates Circadian Expression
0.0	0.3	REACTOME GAP JUNCTION DEGRADATION	Genes involved in Gap junction degradation
0.0	0.3	REACTOME SEMA3A PAK DEPENDENT AXON REPULSION	Genes involved in Sema3A PAK dependent Axon repulsion
0.0	0.8	REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE	Genes involved in Synthesis of PIPs at the plasma membrane
0.0	0.7	REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING	Genes involved in Downregulation of TGF-beta receptor signaling
0.0	0.4	REACTOME HIGHLY CALCIUM PERMEABLE POSTSYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS	Genes involved in Highly calcium permeable postsynaptic nicotinic acetylcholine receptors
0.0	0.2	REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION	Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.0	0.6	REACTOME EFFECTS OF PIP2 HYDROLYSIS	Genes involved in Effects of PIP2 hydrolysis
0.0	0.3	REACTOME RAS ACTIVATION UOPN CA2 INFUX THROUGH NMDA RECEPTOR	Genes involved in Ras activation uopn Ca2+ infux through NMDA receptor
0.0	0.1	REACTOME CTLA4 INHIBITORY SIGNALING	Genes involved in CTLA4 inhibitory signaling
0.0	0.3	REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE	Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.0	0.2	REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 3 PROMOTER	Genes involved in RNA Polymerase III Transcription Initiation From Type 3 Promoter
0.0	0.0	REACTOME DESTABILIZATION OF MRNA BY KSRP	Genes involved in Destabilization of mRNA by KSRP
0.0	0.5	REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS	Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.0	0.4	REACTOME CTNNB1 PHOSPHORYLATION CASCADE	Genes involved in Beta-catenin phosphorylation cascade
0.0	0.4	REACTOME REGULATORY RNA PATHWAYS	Genes involved in Regulatory RNA pathways
0.0	0.3	REACTOME ALPHA LINOLENIC ACID ALA METABOLISM	Genes involved in alpha-linolenic acid (ALA) metabolism
0.0	0.8	REACTOME GLYCOSPHINGOLIPID METABOLISM	Genes involved in Glycosphingolipid metabolism
0.0	0.1	REACTOME TGF BETA RECEPTOR SIGNALING ACTIVATES SMADS	Genes involved in TGF-beta receptor signaling activates SMADs
0.0	0.1	REACTOME IL 7 SIGNALING	Genes involved in Interleukin-7 signaling
0.0	0.2	REACTOME COPI MEDIATED TRANSPORT	Genes involved in COPI Mediated Transport
0.0	0.6	REACTOME TRANSPORT OF RIBONUCLEOPROTEINS INTO THE HOST NUCLEUS	Genes involved in Transport of Ribonucleoproteins into the Host Nucleus
0.0	0.2	REACTOME ACTIVATION OF BH3 ONLY PROTEINS	Genes involved in Activation of BH3-only proteins
0.0	0.5	REACTOME EXTENSION OF TELOMERES	Genes involved in Extension of Telomeres
0.0	0.4	REACTOME NOD1 2 SIGNALING PATHWAY	Genes involved in NOD1/2 Signaling Pathway
0.0	0.3	REACTOME FANCONI ANEMIA PATHWAY	Genes involved in Fanconi Anemia pathway
0.0	0.1	REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION	Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.0	0.1	REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC	Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.0	0.5	REACTOME REGULATION OF BETA CELL DEVELOPMENT	Genes involved in Regulation of beta-cell development
0.0	0.1	REACTOME DSCAM INTERACTIONS	Genes involved in DSCAM interactions
0.0	0.1	REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS	Genes involved in Activation of the AP-1 family of transcription factors
0.0	0.1	REACTOME INTEGRATION OF PROVIRUS	Genes involved in Integration of provirus
0.0	0.1	REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS	Genes involved in Membrane binding and targetting of GAG proteins
0.0	0.3	REACTOME RNA POL I TRANSCRIPTION INITIATION	Genes involved in RNA Polymerase I Transcription Initiation
0.0	0.0	REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION	Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.0	0.3	REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS	Genes involved in ABCA transporters in lipid homeostasis
0.0	0.4	REACTOME G1 PHASE	Genes involved in G1 Phase
0.0	0.9	REACTOME INTERFERON ALPHA BETA SIGNALING	Genes involved in Interferon alpha/beta signaling
0.0	0.2	REACTOME NUCLEOTIDE LIKE PURINERGIC RECEPTORS	Genes involved in Nucleotide-like (purinergic) receptors
0.0	0.3	REACTOME LYSOSOME VESICLE BIOGENESIS	Genes involved in Lysosome Vesicle Biogenesis
0.0	0.3	REACTOME INSULIN SYNTHESIS AND PROCESSING	Genes involved in Insulin Synthesis and Processing
0.0	0.3	REACTOME CHOLESTEROL BIOSYNTHESIS	Genes involved in Cholesterol biosynthesis
0.0	0.0	REACTOME RNA POL I PROMOTER OPENING	Genes involved in RNA Polymerase I Promoter Opening
0.0	0.0	REACTOME INTERACTIONS OF VPR WITH HOST CELLULAR PROTEINS	Genes involved in Interactions of Vpr with host cellular proteins
0.0	0.0	REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION	Genes involved in activated TAK1 mediates p38 MAPK activation
0.0	0.9	REACTOME P75 NTR RECEPTOR MEDIATED SIGNALLING	Genes involved in p75 NTR receptor-mediated signalling
0.0	0.0	REACTOME TRAF3 DEPENDENT IRF ACTIVATION PATHWAY	Genes involved in TRAF3-dependent IRF activation pathway
0.0	0.2	REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS	Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.0	0.0	REACTOME SHC MEDIATED SIGNALLING	Genes involved in SHC-mediated signalling
0.0	0.1	REACTOME RETROGRADE NEUROTROPHIN SIGNALLING	Genes involved in Retrograde neurotrophin signalling
0.0	0.2	REACTOME TRANSPORT TO THE GOLGI AND SUBSEQUENT MODIFICATION	Genes involved in Transport to the Golgi and subsequent modification
0.0	0.7	REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES	Genes involved in Chemokine receptors bind chemokines
0.0	0.1	REACTOME ARMS MEDIATED ACTIVATION	Genes involved in ARMS-mediated activation
0.0	0.2	REACTOME DARPP 32 EVENTS	Genes involved in DARPP-32 events
0.0	0.6	REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL	Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0	0.1	REACTOME IL 6 SIGNALING	Genes involved in Interleukin-6 signaling
0.0	0.0	REACTOME IRAK1 RECRUITS IKK COMPLEX	Genes involved in IRAK1 recruits IKK complex
0.0	0.1	REACTOME ASSOCIATION OF LICENSING FACTORS WITH THE PRE REPLICATIVE COMPLEX	Genes involved in Association of licensing factors with the pre-replicative complex
0.0	0.2	REACTOME SYNTHESIS OF PC	Genes involved in Synthesis of PC
0.0	0.0	REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING	Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
0.0	0.4	REACTOME MRNA SPLICING MINOR PATHWAY	Genes involved in mRNA Splicing - Minor Pathway
0.0	0.0	REACTOME DESTABILIZATION OF MRNA BY AUF1 HNRNP D0	Genes involved in Destabilization of mRNA by AUF1 (hnRNP D0)
0.0	0.2	REACTOME ACYL CHAIN REMODELLING OF PS	Genes involved in Acyl chain remodelling of PS
0.0	0.2	REACTOME ZINC TRANSPORTERS	Genes involved in Zinc transporters
0.0	0.1	REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP	Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.0	0.0	REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING	Genes involved in Advanced glycosylation endproduct receptor signaling
0.0	0.2	REACTOME DEADENYLATION OF MRNA	Genes involved in Deadenylation of mRNA
0.0	0.0	REACTOME TRANSPORT OF MATURE MRNA DERIVED FROM AN INTRONLESS TRANSCRIPT	Genes involved in Transport of Mature mRNA Derived from an Intronless Transcript
0.0	0.2	REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES	Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.0	0.0	REACTOME PRE NOTCH TRANSCRIPTION AND TRANSLATION	Genes involved in Pre-NOTCH Transcription and Translation
0.0	0.1	REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT	Genes involved in Chylomicron-mediated lipid transport
0.0	0.0	REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR	Genes involved in Trafficking and processing of endosomal TLR
0.0	0.4	REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY	Genes involved in Nuclear Receptor transcription pathway
0.0	0.1	REACTOME DOUBLE STRAND BREAK REPAIR	Genes involved in Double-Strand Break Repair
0.0	0.1	REACTOME GABA A RECEPTOR ACTIVATION	Genes involved in GABA A receptor activation
0.0	0.1	REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA	Genes involved in Activation of Chaperone Genes by ATF6-alpha

Results for PROX1

Z-value: 1.94

Motif logo

Transcription factors associated with PROX1

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

Activity of the PROX1 motif across conditions

Conditions sorted by the z-value of the PROX1 motif activity

Top target CREs of the motif:

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of PROX1

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category:

Gene overrepresentation in curated gene sets: canonical pathways category:

Gene overrepresentation in curated gene sets: REACTOME pathways category: