Project
ENCODE: H3K4me1 ChIP-Seq of primary human cells
Navigation
Downloads
Logo
CREMA is a free online tool that recognizes most important transcription factors that change the chromatin state across different samples.

Results for PRRX1_ALX4_PHOX2A

Z-value: 1.33

Motif logo

logo of logo of logo of

Transcription factors associated with PRRX1_ALX4_PHOX2A

Gene Symbol Gene ID Gene Info
ENSG00000116132.7 PRRX1
ENSG00000052850.5 ALX4
ENSG00000165462.5 PHOX2A

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE Gene Distance Association probability Pearson corr. coef. P-value Plot
ALX4chr11_44250739_44250890809020.0959360.872.0e-03Click!
ALX4chr11_44355050_44355201234090.2579450.844.5e-03Click!
ALX4chr11_44267220_44267371644210.1291000.771.5e-02Click!
ALX4chr11_44338062_4433829764630.3124670.761.6e-02Click!
ALX4chr11_44327279_4432743043620.3373260.742.3e-02Click!
PHOX2Achr11_71950564_7195074015840.2237770.781.4e-02Click!
PHOX2Achr11_71954813_719549693290.8082910.452.2e-01Click!
PHOX2Achr11_71951037_719515689340.3985440.452.3e-01Click!
PHOX2Achr11_71955544_719557224130.7444370.412.7e-01Click!
PHOX2Achr11_71981001_71981152258560.0963310.373.3e-01Click!
PRRX1chr1_170630132_17063040020090.4566100.791.1e-02Click!
PRRX1chr1_170662175_170662326291720.2362150.761.8e-02Click!
PRRX1chr1_170761566_1707617171285630.0509190.752.0e-02Click!
PRRX1chr1_170681487_170681638484840.1769240.742.1e-02Click!
PRRX1chr1_170662643_170662794296400.2347620.742.3e-02Click!

Activity of the PRRX1_ALX4_PHOX2A motif across conditions

Conditions sorted by the z-value of the PRRX1_ALX4_PHOX2A motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE) Target Score Top associated gene Gene Info Distance of CRE to TSS CRE/Gene association probability
chr2_28027295_28027627 1.84 AC110084.1

18275
0.15
chr5_39072103_39073220 1.80 RICTOR
RPTOR independent companion of MTOR, complex 2
1830
0.43
chr7_115872460_115873536 1.75 AC073130.3

6307
0.23
chr5_81460698_81461288 1.71 ENSG00000265684
.
86747
0.08
chr3_138581340_138581807 1.70 PIK3CB
phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta
27793
0.2
chr4_170069367_170069518 1.67 RP11-327O17.2

53503
0.15
chr10_65024052_65024675 1.66 JMJD1C
jumonji domain containing 1C
4463
0.31
chr1_173160112_173160263 1.64 TNFSF4
tumor necrosis factor (ligand) superfamily, member 4
14510
0.27
chr10_72746069_72746220 1.62 PCBD1
pterin-4 alpha-carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha
97603
0.07
chr5_53387008_53387159 1.57 ENSG00000265421
.
15670
0.24
chr5_110849348_110849548 1.56 STARD4
StAR-related lipid transfer (START) domain containing 4
1160
0.42
chr3_99670847_99671142 1.50 ENSG00000264897
.
12248
0.26
chr10_52085009_52085183 1.47 AC069547.1
HCG1745369; PRO3073; Uncharacterized protein
9202
0.2
chr8_62631448_62632036 1.47 ENSG00000264408
.
4395
0.26
chr6_7640858_7641250 1.45 SNRNP48
small nuclear ribonucleoprotein 48kDa (U11/U12)
50622
0.15
chr7_111930402_111930553 1.40 ENSG00000202406
.
1799
0.41
chr9_87839084_87839235 1.39 AGTPBP1
ATP/GTP binding protein 1
457042
0.01
chr17_60897719_60897987 1.39 MARCH10
membrane-associated ring finger (C3HC4) 10, E3 ubiquitin protein ligase
12148
0.25
chr7_17812443_17812892 1.39 SNX13
sorting nexin 13
167424
0.04
chr4_39938914_39939065 1.37 ENSG00000252970
.
616
0.76
chr2_201725693_201726476 1.36 ENSG00000252759
.
1886
0.16
chr10_21653175_21653326 1.36 ENSG00000207264
.
42360
0.16
chr14_51909030_51909181 1.35 FRMD6
FERM domain containing 6
46750
0.16
chr6_114290051_114291212 1.35 RP3-399L15.3

234
0.87
chr18_12403385_12403680 1.34 ENSG00000251937
.
3121
0.2
chr1_25666704_25667414 1.33 ENSG00000252515
.
403
0.75
chr10_34816673_34816973 1.31 PARD3
par-3 family cell polarity regulator
101164
0.08
chr13_24462234_24462908 1.28 C1QTNF9B-AS1
C1QTNF9B antisense RNA 1
457
0.68
chr15_36043717_36043868 1.28 ENSG00000265098
.
175265
0.03
chr13_49672637_49672967 1.26 ENSG00000199788
.
3275
0.28
chr11_19222231_19222783 1.25 CSRP3
cysteine and glycine-rich protein 3 (cardiac LIM protein)
1082
0.5
chr4_182873494_182873645 1.24 ENSG00000251742
.
117308
0.06
chr7_137276747_137277035 1.23 PTN
pleiotrophin
248280
0.02
chr20_19795494_19795742 1.22 AL121761.2
Uncharacterized protein
56939
0.12
chr18_20714051_20714237 1.22 CABLES1
Cdk5 and Abl enzyme substrate 1
384
0.85
chr16_72909394_72909957 1.21 ENSG00000251868
.
53784
0.12
chr6_134381453_134381604 1.20 SLC2A12
solute carrier family 2 (facilitated glucose transporter), member 12
7754
0.26
chr6_16338797_16338948 1.19 ENSG00000265642
.
89882
0.08
chr3_156469900_156470185 1.19 TIPARP
TCDD-inducible poly(ADP-ribose) polymerase
71087
0.1
chr8_67834607_67835072 1.18 ENSG00000245910
.
49
0.5
chr2_143632216_143632516 1.17 KYNU
kynureninase
2701
0.42
chr17_59887802_59887953 1.17 BRIP1
BRCA1 interacting protein C-terminal helicase 1
34036
0.18
chr13_105998207_105998358 1.17 DAOA
D-amino acid oxidase activator
120310
0.07
chr3_174978584_174978880 1.16 NAALADL2-AS2
NAALADL2 antisense RNA 2
10153
0.29
chr3_51654767_51654946 1.16 RAD54L2
RAD54-like 2 (S. cerevisiae)
8551
0.17
chr3_197098695_197098846 1.15 ENSG00000238491
.
32348
0.17
chr8_38857849_38858000 1.15 ADAM9
ADAM metallopeptidase domain 9
3419
0.17
chr3_38195122_38195273 1.14 OXSR1
oxidative stress responsive 1
11799
0.14
chr2_171381868_171382019 1.14 AC007277.3

118511
0.06
chr1_234858071_234858911 1.11 IRF2BP2
interferon regulatory factor 2 binding protein 2
113220
0.06
chr11_26621404_26621555 1.11 MUC15
mucin 15, cell surface associated
27699
0.25
chr9_127174736_127174887 1.11 PSMB7
proteasome (prosome, macropain) subunit, beta type, 7
2907
0.27
chr9_118378678_118378829 1.11 DEC1
deleted in esophageal cancer 1
474656
0.01
chr21_30331573_30331724 1.11 LTN1
listerin E3 ubiquitin protein ligase 1
33558
0.14
chr11_130451238_130451517 1.11 C11orf44
chromosome 11 open reading frame 44
91474
0.09
chr1_90408832_90409267 1.11 ENSG00000252797
.
44454
0.16
chr6_86164371_86164522 1.10 NT5E
5'-nucleotidase, ecto (CD73)
4619
0.31
chr2_197264610_197264832 1.09 HECW2
HECT, C2 and WW domain containing E3 ubiquitin protein ligase 2
37775
0.2
chr7_134574979_134575413 1.09 CALD1
caldesmon 1
955
0.69
chr14_35352688_35352839 1.09 BAZ1A
bromodomain adjacent to zinc finger domain, 1A
7910
0.16
chr8_103802696_103803356 1.09 ENSG00000266799
.
57079
0.11
chr10_126029460_126029611 1.08 OAT
ornithine aminotransferase
77970
0.1
chr1_67397953_67399117 1.08 MIER1
mesoderm induction early response 1, transcriptional regulator
2609
0.29
chr1_198143089_198143887 1.08 NEK7
NIMA-related kinase 7
17237
0.29
chr12_26150271_26150549 1.08 RASSF8
Ras association (RalGDS/AF-6) domain family (N-terminal) member 8
2473
0.34
chr10_112084409_112084560 1.08 SMNDC1
survival motor neuron domain containing 1
19775
0.22
chr14_72014650_72014936 1.07 SIPA1L1
signal-induced proliferation-associated 1 like 1
18751
0.27
chr1_163142417_163142568 1.07 RP11-267N12.1

11027
0.22
chr8_29109260_29109557 1.07 KIF13B
kinesin family member 13B
11182
0.17
chr3_50597329_50597480 1.06 C3orf18
chromosome 3 open reading frame 18
1938
0.27
chr10_126782266_126782505 1.05 ENSG00000264572
.
60946
0.12
chr16_53809610_53810340 1.05 FTO
fat mass and obesity associated
71881
0.11
chr14_31496888_31497108 1.04 AP4S1
adaptor-related protein complex 4, sigma 1 subunit
1149
0.38
chr15_79932504_79932655 1.03 ENSG00000252995
.
177213
0.03
chr15_48707592_48707743 1.03 DUT
deoxyuridine triphosphatase
83064
0.08
chr15_96898066_96898266 1.03 AC087477.1
Uncharacterized protein
6321
0.18
chr2_147739330_147739481 1.03 ENSG00000238860
.
342134
0.01
chr1_165798685_165799109 1.02 UCK2
uridine-cytidine kinase 2
1838
0.29
chr11_63570630_63570781 1.01 ENSG00000264519
.
5162
0.17
chr2_63926298_63926449 1.01 ENSG00000221085
.
3704
0.33
chr3_104591866_104592017 1.01 ALCAM
activated leukocyte cell adhesion molecule
493812
0.01
chr14_78060038_78060870 1.01 SPTLC2
serine palmitoyltransferase, long chain base subunit 2
3210
0.25
chr6_56393583_56393862 1.01 DST
dystonin
54934
0.15
chr4_53966535_53966686 1.00 RP11-752D24.2

154754
0.04
chr11_109870547_109870746 1.00 ZC3H12C
zinc finger CCCH-type containing 12C
93441
0.1
chr9_82225057_82225416 1.00 TLE4
transducin-like enhancer of split 4 (E(sp1) homolog, Drosophila)
36632
0.25
chr17_28275117_28275440 1.00 EFCAB5
EF-hand calcium binding domain 5
6655
0.17
chr6_140364803_140364954 0.99 ENSG00000252107
.
114953
0.07
chr3_59876683_59876834 0.99 NPCDR1
nasopharyngeal carcinoma, down-regulated 1
80825
0.12
chr2_179317057_179317208 0.99 DFNB59
deafness, autosomal recessive 59
862
0.41
chr3_64172202_64172494 0.98 PRICKLE2-AS3
PRICKLE2 antisense RNA 3
872
0.63
chr12_69003602_69004056 0.98 RAP1B
RAP1B, member of RAS oncogene family
790
0.68
chr10_93221945_93222246 0.98 HECTD2
HECT domain containing E3 ubiquitin protein ligase 2
198
0.97
chr4_1581689_1582176 0.98 FAM53A
family with sequence similarity 53, member A
75203
0.08
chr14_23309465_23309695 0.97 MMP14
matrix metallopeptidase 14 (membrane-inserted)
3059
0.11
chr3_184283830_184284128 0.97 EPHB3
EPH receptor B3
4407
0.22
chr1_113305123_113305296 0.97 FAM19A3
family with sequence similarity 19 (chemokine (C-C motif)-like), member A3
42010
0.1
chr17_79378177_79378500 0.96 ENSG00000266392
.
3760
0.14
chr8_108472941_108473092 0.96 ANGPT1
angiopoietin 1
34207
0.25
chr17_71223137_71223697 0.96 FAM104A
family with sequence similarity 104, member A
422
0.78
chr6_72188105_72188315 0.96 ENSG00000212099
.
60469
0.12
chr4_24553435_24554115 0.96 ENSG00000243005
.
11309
0.21
chr6_100678658_100678809 0.96 RP1-121G13.2

196261
0.03
chr8_38264429_38264741 0.95 RP11-350N15.6

1675
0.23
chr1_207070153_207070445 0.95 IL24
interleukin 24
489
0.76
chr13_21388861_21389012 0.95 N6AMT2
N-6 adenine-specific DNA methyltransferase 2 (putative)
40848
0.16
chr3_104914344_104914495 0.95 ALCAM
activated leukocyte cell adhesion molecule
171334
0.04
chr6_47210690_47211031 0.95 TNFRSF21
tumor necrosis factor receptor superfamily, member 21
66781
0.13
chr18_10213675_10214158 0.95 ENSG00000239031
.
176081
0.03
chr2_239772602_239772753 0.94 TWIST2
twist family bHLH transcription factor 2
16004
0.24
chr11_106328368_106328519 0.94 RP11-680E19.1

193401
0.03
chr9_86886066_86886420 0.94 RP11-380F14.2

6891
0.29
chr3_106941061_106941212 0.93 ENSG00000220989
.
142893
0.05
chr8_119428390_119428541 0.93 AC023590.1
Uncharacterized protein
133984
0.05
chr3_14668494_14668645 0.93 AC090952.5

22370
0.17
chr15_40012595_40012873 0.93 RP11-37C7.3

62038
0.1
chr5_73730230_73730381 0.92 ENSG00000244326
.
116494
0.06
chr10_3138171_3138455 0.92 PFKP
phosphofructokinase, platelet
8603
0.25
chr6_125683988_125684554 0.92 RP11-735G4.1

11199
0.27
chr10_126632554_126632798 0.92 ZRANB1
zinc finger, RAN-binding domain containing 1
1984
0.27
chr15_94780403_94780640 0.92 MCTP2
multiple C2 domains, transmembrane 2
5754
0.35
chr3_185450541_185450692 0.92 C3orf65
chromosome 3 open reading frame 65
19536
0.2
chr8_95236664_95236815 0.91 CDH17
cadherin 17, LI cadherin (liver-intestine)
7208
0.25
chr22_24878693_24878966 0.91 ADORA2A-AS1
ADORA2A antisense RNA 1
11934
0.14
chr6_35149420_35149571 0.91 SCUBE3
signal peptide, CUB domain, EGF-like 3
32695
0.14
chr1_95436960_95437111 0.91 RP4-639F20.1

10154
0.2
chr4_184276815_184276966 0.90 ENSG00000238596
.
26439
0.12
chr7_74602162_74602449 0.90 GTF2IRD2B
GTF2I repeat domain containing 2B
45401
0.16
chr15_78594610_78594888 0.90 WDR61
WD repeat domain 61
2613
0.18
chr5_149432633_149432842 0.90 ENSG00000238369
.
23722
0.12
chr17_39183900_39184201 0.89 KRTAP1-5
keratin associated protein 1-5
596
0.43
chr6_108886651_108887051 0.89 FOXO3
forkhead box O3
4782
0.33
chr13_106767898_106768049 0.89 ENSG00000222643
.
12747
0.26
chr7_16168760_16168911 0.89 ISPD-AS1
ISPD antisense RNA 1
81278
0.11
chr8_119856274_119856425 0.89 TNFRSF11B
tumor necrosis factor receptor superfamily, member 11b
108090
0.07
chr20_10600399_10600550 0.88 JAG1
jagged 1
42680
0.18
chr2_60756881_60757175 0.88 BCL11A
B-cell CLL/lymphoma 11A (zinc finger protein)
23512
0.2
chr15_73974098_73974249 0.88 CD276
CD276 molecule
2134
0.36
chr10_60536522_60536673 0.88 BICC1
bicaudal C homolog 1 (Drosophila)
16698
0.28
chr22_40906008_40906449 0.88 RP4-591N18.2

11576
0.17
chr4_183228725_183228876 0.88 TENM3
teneurin transmembrane protein 3
16374
0.28
chr12_65701995_65702560 0.88 MSRB3
methionine sulfoxide reductase B3
18378
0.22
chr1_27472244_27472495 0.87 SLC9A1
solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1
8604
0.21
chr3_111623515_111623944 0.87 PHLDB2
pleckstrin homology-like domain, family B, member 2
6728
0.26
chr12_27701070_27701221 0.87 PPFIBP1
PTPRF interacting protein, binding protein 1 (liprin beta 1)
10089
0.24
chr8_82452135_82452286 0.86 FABP12
fatty acid binding protein 12
8597
0.18
chr2_178283039_178283431 0.86 AGPS
alkylglycerone phosphate synthase
25739
0.14
chr6_79325243_79325394 0.86 IRAK1BP1
interleukin-1 receptor-associated kinase 1 binding protein 1
251871
0.02
chr12_57077760_57078152 0.86 PTGES3
prostaglandin E synthase 3 (cytosolic)
3990
0.14
chr2_75819618_75819769 0.85 EVA1A
eva-1 homolog A (C. elegans)
22845
0.13
chr9_71772774_71772925 0.85 TJP2
tight junction protein 2
6283
0.28
chr4_130264478_130264721 0.85 C4orf33
chromosome 4 open reading frame 33
247274
0.02
chr10_89987215_89987417 0.85 ENSG00000200891
.
232864
0.02
chr4_54828683_54828834 0.85 RP11-89B16.1

62720
0.12
chr17_9274614_9274765 0.85 AC087501.1

80825
0.08
chr15_40793575_40793726 0.84 RP11-111A22.1

6573
0.11
chr6_108975764_108975915 0.84 FOXO3
forkhead box O3
1710
0.51
chr8_118411718_118411869 0.84 ENSG00000252852
.
86026
0.1
chr3_93944340_93944491 0.84 ENSG00000253062
.
127005
0.05
chr12_123850609_123850766 0.84 SBNO1
strawberry notch homolog 1 (Drosophila)
1297
0.36
chr6_4317363_4317768 0.84 ENSG00000201185
.
110632
0.06
chr6_15443979_15444308 0.84 JARID2
jumonji, AT rich interactive domain 2
43054
0.18
chr11_120256554_120256705 0.84 ARHGEF12
Rho guanine nucleotide exchange factor (GEF) 12
626
0.76
chr2_65581901_65582416 0.83 SPRED2
sprouty-related, EVH1 domain containing 2
10238
0.23
chr12_47515337_47515488 0.83 AMIGO2
adhesion molecule with Ig-like domain 2
41678
0.15
chr3_18280229_18280380 0.83 RP11-158G18.1

170823
0.04
chr3_174984617_174984768 0.83 NAALADL2-AS2
NAALADL2 antisense RNA 2
4193
0.33
chr1_100110656_100110807 0.83 PALMD
palmdelphin
768
0.75
chr2_102953273_102953559 0.83 IL1RL1
interleukin 1 receptor-like 1
192
0.95
chr10_63546087_63546274 0.82 RP11-63A2.2

101034
0.07
chr4_99437057_99437281 0.82 RP11-724M22.1

19654
0.26
chrX_24073482_24074722 0.82 EIF2S3
eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa
1014
0.57
chr17_48718114_48718630 0.82 ABCC3
ATP-binding cassette, sub-family C (CFTR/MRP), member 3
6154
0.13
chr3_98690834_98690985 0.82 ENSG00000207331
.
63606
0.11
chr17_60074998_60075962 0.82 ENSG00000242398
.
7868
0.17
chr1_25054262_25054430 0.81 CLIC4
chloride intracellular channel 4
17502
0.19
chr7_77496191_77496692 0.81 PHTF2
putative homeodomain transcription factor 2
26944
0.18
chr11_78509149_78509300 0.81 TENM4
teneurin transmembrane protein 4
7232
0.27
chr13_34612377_34612528 0.81 ENSG00000199196
.
62523
0.15
chr21_16295569_16295720 0.81 AF127577.8

4789
0.25
chr12_26163065_26163216 0.81 RASSF8
Ras association (RalGDS/AF-6) domain family (N-terminal) member 8
1529
0.47
chr7_17182190_17182792 0.81 AC003075.4

138436
0.05
chr2_160541641_160541938 0.81 MARCH7
membrane-associated ring finger (C3HC4) 7, E3 ubiquitin protein ligase
27211
0.2
chr3_176843598_176843767 0.81 ENSG00000200882
.
226
0.94
chr12_116702764_116703198 0.80 ENSG00000263768
.
9188
0.22
chr17_60904793_60905165 0.80 MARCH10
membrane-associated ring finger (C3HC4) 10, E3 ubiquitin protein ligase
19274
0.23
chr3_45085178_45085379 0.80 ENSG00000252410
.
9198
0.18
chr10_31939152_31939303 0.80 ENSG00000222412
.
105837
0.07
chr13_45781222_45781373 0.80 KCTD4
potassium channel tetramerization domain containing 4
6122
0.21
chr1_68179057_68179290 0.80 GADD45A
growth arrest and DNA-damage-inducible, alpha
28289
0.18
chr4_102321098_102321249 0.80 BANK1
B-cell scaffold protein with ankyrin repeats 1
19945
0.21
chr10_34451871_34452022 0.80 ENSG00000199200
.
39056
0.23
chr18_55844158_55844426 0.80 NEDD4L
neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase
18330
0.21
chr12_27713334_27713485 0.80 PPFIBP1
PTPRF interacting protein, binding protein 1 (liprin beta 1)
22353
0.21
chr7_80633166_80633317 0.80 SEMA3C
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C
81566
0.11
chr3_49384271_49384510 0.80 USP4
ubiquitin specific peptidase 4 (proto-oncogene)
6886
0.11
chr9_98617344_98617495 0.79 ENSG00000252847
.
4767
0.23
chr6_8084504_8084655 0.79 EEF1E1
eukaryotic translation elongation factor 1 epsilon 1
12965
0.22
chr2_225876064_225876450 0.79 ENSG00000263828
.
1000
0.66
chr1_172325413_172325564 0.79 ENSG00000252354
.
8205
0.18

Histogram of CRE-TSS distances for CREs targeted by :

Histogram of

Rank distribution of CRE target scores:

Histogram of target CRE score.

Distribution of target CREs across different genomic regions:

Weighted Piechart of Weighted Piechart of Weighted Piechart of

Network of associatons between targets according to the STRING database.

StringDB image

First level regulatory network of PRRX1_ALX4_PHOX2A

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.


View svg image
View png image

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.0 GO:0071277 cellular response to calcium ion(GO:0071277)
0.2 1.5 GO:0001547 antral ovarian follicle growth(GO:0001547)
0.2 1.5 GO:0097061 dendritic spine morphogenesis(GO:0060997) regulation of dendritic spine morphogenesis(GO:0061001) dendritic spine organization(GO:0097061)
0.2 0.7 GO:0007221 positive regulation of transcription of Notch receptor target(GO:0007221)
0.2 0.2 GO:1904668 positive regulation of ubiquitin protein ligase activity(GO:1904668)
0.2 0.9 GO:0060666 dichotomous subdivision of terminal units involved in salivary gland branching(GO:0060666)
0.2 0.6 GO:0006667 sphinganine metabolic process(GO:0006667)
0.2 0.8 GO:0043497 regulation of protein heterodimerization activity(GO:0043497)
0.2 0.6 GO:2000114 regulation of establishment of cell polarity(GO:2000114)
0.2 0.6 GO:0060633 negative regulation of transcription initiation from RNA polymerase II promoter(GO:0060633) negative regulation of DNA-templated transcription, initiation(GO:2000143)
0.2 0.7 GO:0001675 acrosome assembly(GO:0001675)
0.2 1.2 GO:0035413 positive regulation of catenin import into nucleus(GO:0035413)
0.2 0.5 GO:0071379 cellular response to prostaglandin stimulus(GO:0071379)
0.2 0.7 GO:0009169 purine nucleoside monophosphate catabolic process(GO:0009128) ribonucleoside monophosphate catabolic process(GO:0009158) purine ribonucleoside monophosphate catabolic process(GO:0009169)
0.2 0.3 GO:0090081 regulation of heart induction by regulation of canonical Wnt signaling pathway(GO:0090081)
0.2 1.2 GO:0007185 transmembrane receptor protein tyrosine phosphatase signaling pathway(GO:0007185)
0.2 0.3 GO:0048669 collateral sprouting in absence of injury(GO:0048669)
0.2 0.5 GO:0032488 Cdc42 protein signal transduction(GO:0032488)
0.2 0.5 GO:0060839 endothelial cell fate commitment(GO:0060839)
0.1 0.3 GO:1901798 positive regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043517) positive regulation of signal transduction by p53 class mediator(GO:1901798)
0.1 0.4 GO:0019805 quinolinate biosynthetic process(GO:0019805)
0.1 0.4 GO:0032467 positive regulation of cytokinesis(GO:0032467)
0.1 0.6 GO:0045077 negative regulation of interferon-gamma biosynthetic process(GO:0045077)
0.1 0.5 GO:0034501 protein localization to kinetochore(GO:0034501)
0.1 0.5 GO:0019934 cGMP-mediated signaling(GO:0019934)
0.1 0.3 GO:0090162 establishment of epithelial cell polarity(GO:0090162)
0.1 0.3 GO:0051280 negative regulation of release of sequestered calcium ion into cytosol(GO:0051280) positive regulation of sequestering of calcium ion(GO:0051284) negative regulation of calcium ion transmembrane transport(GO:1903170)
0.1 0.5 GO:0043116 negative regulation of vascular permeability(GO:0043116)
0.1 0.5 GO:0031340 positive regulation of vesicle fusion(GO:0031340)
0.1 0.2 GO:0046882 negative regulation of follicle-stimulating hormone secretion(GO:0046882)
0.1 0.4 GO:0033147 negative regulation of intracellular estrogen receptor signaling pathway(GO:0033147)
0.1 0.7 GO:0002634 regulation of germinal center formation(GO:0002634)
0.1 0.6 GO:0060040 retinal bipolar neuron differentiation(GO:0060040)
0.1 0.6 GO:0035089 establishment of apical/basal cell polarity(GO:0035089) establishment of monopolar cell polarity(GO:0061162) establishment or maintenance of monopolar cell polarity(GO:0061339)
0.1 0.5 GO:0033600 negative regulation of mammary gland epithelial cell proliferation(GO:0033600)
0.1 1.1 GO:0007020 microtubule nucleation(GO:0007020)
0.1 0.7 GO:0035162 embryonic hemopoiesis(GO:0035162)
0.1 0.2 GO:0048143 astrocyte activation(GO:0048143)
0.1 0.2 GO:0060900 embryonic camera-type eye formation(GO:0060900)
0.1 0.1 GO:0048087 positive regulation of developmental pigmentation(GO:0048087)
0.1 0.2 GO:0006065 UDP-glucuronate biosynthetic process(GO:0006065)
0.1 0.4 GO:0072112 renal filtration cell differentiation(GO:0061318) glomerular epithelium development(GO:0072010) glomerular visceral epithelial cell differentiation(GO:0072112) glomerular epithelial cell differentiation(GO:0072311)
0.1 0.4 GO:0061213 positive regulation of mesonephros development(GO:0061213) positive regulation of branching involved in ureteric bud morphogenesis(GO:0090190)
0.1 0.3 GO:0006883 cellular sodium ion homeostasis(GO:0006883)
0.1 0.3 GO:0035583 sequestering of extracellular ligand from receptor(GO:0035581) sequestering of TGFbeta in extracellular matrix(GO:0035583) protein localization to extracellular region(GO:0071692) maintenance of protein location in extracellular region(GO:0071694) extracellular regulation of signal transduction(GO:1900115) extracellular negative regulation of signal transduction(GO:1900116)
0.1 0.5 GO:0048625 myoblast fate commitment(GO:0048625)
0.1 0.3 GO:0007132 meiotic metaphase I(GO:0007132)
0.1 0.3 GO:0017121 phospholipid scrambling(GO:0017121)
0.1 0.3 GO:0030091 protein repair(GO:0030091)
0.1 0.3 GO:0034638 phosphatidylcholine catabolic process(GO:0034638)
0.1 0.3 GO:0022038 corpus callosum development(GO:0022038)
0.1 0.3 GO:0060831 smoothened signaling pathway involved in dorsal/ventral neural tube patterning(GO:0060831)
0.1 0.5 GO:0009200 deoxyribonucleoside triphosphate metabolic process(GO:0009200)
0.1 0.6 GO:0033137 negative regulation of peptidyl-serine phosphorylation(GO:0033137)
0.1 0.2 GO:0048845 venous blood vessel morphogenesis(GO:0048845)
0.1 0.3 GO:0040016 embryonic cleavage(GO:0040016)
0.1 0.1 GO:0071421 manganese ion transmembrane transport(GO:0071421)
0.1 0.4 GO:0030579 ubiquitin-dependent SMAD protein catabolic process(GO:0030579)
0.1 0.3 GO:0035067 negative regulation of histone acetylation(GO:0035067) negative regulation of protein acetylation(GO:1901984) negative regulation of peptidyl-lysine acetylation(GO:2000757)
0.1 0.3 GO:0048170 positive regulation of long-term neuronal synaptic plasticity(GO:0048170)
0.1 0.7 GO:0006108 malate metabolic process(GO:0006108)
0.1 0.3 GO:0051387 negative regulation of neurotrophin TRK receptor signaling pathway(GO:0051387)
0.1 0.4 GO:0034063 stress granule assembly(GO:0034063)
0.1 0.2 GO:0009756 carbohydrate mediated signaling(GO:0009756)
0.1 0.4 GO:0050932 regulation of melanocyte differentiation(GO:0045634) regulation of pigment cell differentiation(GO:0050932)
0.1 0.3 GO:0032509 endosome transport via multivesicular body sorting pathway(GO:0032509)
0.1 0.2 GO:0032344 regulation of ketone biosynthetic process(GO:0010566) regulation of aldosterone metabolic process(GO:0032344) regulation of aldosterone biosynthetic process(GO:0032347)
0.1 0.3 GO:0043589 skin morphogenesis(GO:0043589)
0.1 0.7 GO:0019369 arachidonic acid metabolic process(GO:0019369)
0.1 0.1 GO:0006824 cobalt ion transport(GO:0006824)
0.1 0.3 GO:0021898 commitment of multipotent stem cells to neuronal lineage in forebrain(GO:0021898)
0.1 0.3 GO:0006435 threonyl-tRNA aminoacylation(GO:0006435)
0.1 0.4 GO:0009649 entrainment of circadian clock(GO:0009649)
0.1 0.6 GO:0045747 positive regulation of Notch signaling pathway(GO:0045747)
0.1 0.2 GO:0051451 myoblast migration(GO:0051451)
0.1 0.1 GO:0060295 regulation of cilium movement(GO:0003352) regulation of cilium beat frequency(GO:0003356) cilium movement involved in cell motility(GO:0060294) regulation of cilium movement involved in cell motility(GO:0060295) regulation of cilium beat frequency involved in ciliary motility(GO:0060296) regulation of cilium-dependent cell motility(GO:1902019)
0.1 0.4 GO:0043569 negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569)
0.1 0.1 GO:0045964 positive regulation of catecholamine metabolic process(GO:0045915) positive regulation of dopamine metabolic process(GO:0045964)
0.1 0.2 GO:0001996 positive regulation of heart rate by epinephrine-norepinephrine(GO:0001996)
0.1 0.2 GO:0006686 sphingomyelin biosynthetic process(GO:0006686)
0.1 0.3 GO:0018344 protein geranylgeranylation(GO:0018344)
0.1 0.5 GO:0002483 antigen processing and presentation of endogenous peptide antigen(GO:0002483) antigen processing and presentation of endogenous peptide antigen via MHC class I(GO:0019885)
0.1 0.3 GO:0002329 immature B cell differentiation(GO:0002327) pre-B cell differentiation(GO:0002329)
0.1 0.9 GO:0007184 SMAD protein import into nucleus(GO:0007184)
0.1 0.6 GO:0009886 post-embryonic morphogenesis(GO:0009886)
0.1 0.3 GO:0051570 regulation of histone H3-K9 methylation(GO:0051570)
0.1 0.2 GO:0051088 PMA-inducible membrane protein ectodomain proteolysis(GO:0051088)
0.1 0.2 GO:0002577 dendritic cell antigen processing and presentation(GO:0002468) regulation of antigen processing and presentation(GO:0002577) regulation of dendritic cell antigen processing and presentation(GO:0002604)
0.1 0.5 GO:0032055 negative regulation of translation in response to stress(GO:0032055)
0.1 0.1 GO:0071731 response to nitric oxide(GO:0071731)
0.1 0.2 GO:0051877 pigment granule aggregation in cell center(GO:0051877)
0.1 0.2 GO:0032927 positive regulation of activin receptor signaling pathway(GO:0032927)
0.1 0.3 GO:0060754 mast cell chemotaxis(GO:0002551) regulation of mast cell chemotaxis(GO:0060753) positive regulation of mast cell chemotaxis(GO:0060754) mast cell migration(GO:0097531)
0.1 0.1 GO:0002043 blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:0002043)
0.1 0.2 GO:0018242 protein O-linked glycosylation via serine(GO:0018242) protein O-linked glycosylation via threonine(GO:0018243)
0.1 0.3 GO:0045662 negative regulation of myoblast differentiation(GO:0045662)
0.1 0.2 GO:0035511 oxidative DNA demethylation(GO:0035511)
0.1 0.2 GO:0019372 lipoxygenase pathway(GO:0019372)
0.1 0.2 GO:0030422 production of siRNA involved in RNA interference(GO:0030422)
0.1 0.3 GO:0006975 DNA damage induced protein phosphorylation(GO:0006975)
0.1 1.2 GO:0045104 intermediate filament cytoskeleton organization(GO:0045104)
0.1 0.1 GO:0001543 ovarian follicle rupture(GO:0001543)
0.1 0.3 GO:0043922 negative regulation by host of viral transcription(GO:0043922)
0.1 0.2 GO:0050872 white fat cell differentiation(GO:0050872)
0.1 0.1 GO:0060028 convergent extension involved in axis elongation(GO:0060028)
0.1 0.3 GO:0060009 Sertoli cell development(GO:0060009)
0.1 0.4 GO:0002042 cell migration involved in sprouting angiogenesis(GO:0002042)
0.1 0.1 GO:0090281 negative regulation of calcium ion import(GO:0090281)
0.1 0.5 GO:0090136 epithelial cell-cell adhesion(GO:0090136)
0.1 0.3 GO:0045542 positive regulation of cholesterol biosynthetic process(GO:0045542)
0.1 0.3 GO:0007619 courtship behavior(GO:0007619)
0.1 0.1 GO:0032632 interleukin-3 production(GO:0032632)
0.1 0.5 GO:0033327 Leydig cell differentiation(GO:0033327)
0.1 0.1 GO:0060585 regulation of prostaglandin-endoperoxide synthase activity(GO:0060584) positive regulation of prostaglandin-endoperoxide synthase activity(GO:0060585)
0.1 0.2 GO:0070779 D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
0.1 0.3 GO:0070934 CRD-mediated mRNA stabilization(GO:0070934)
0.1 0.2 GO:0015864 pyrimidine nucleoside transport(GO:0015864)
0.1 0.5 GO:0048854 brain morphogenesis(GO:0048854)
0.1 0.1 GO:0060026 convergent extension(GO:0060026)
0.1 0.5 GO:0031000 response to caffeine(GO:0031000)
0.1 0.1 GO:0035385 Roundabout signaling pathway(GO:0035385)
0.1 0.3 GO:0031529 ruffle organization(GO:0031529)
0.1 0.6 GO:0048844 artery morphogenesis(GO:0048844) artery development(GO:0060840)
0.1 0.2 GO:0043276 anoikis(GO:0043276)
0.1 0.3 GO:0001866 NK T cell proliferation(GO:0001866)
0.1 0.2 GO:0060174 limb bud formation(GO:0060174)
0.1 0.1 GO:0090073 positive regulation of protein homodimerization activity(GO:0090073)
0.1 0.1 GO:0042268 regulation of cytolysis(GO:0042268)
0.1 0.2 GO:0070295 renal water absorption(GO:0070295)
0.1 0.1 GO:0002040 sprouting angiogenesis(GO:0002040)
0.1 0.2 GO:0070272 proton-transporting ATP synthase complex assembly(GO:0043461) proton-transporting ATP synthase complex biogenesis(GO:0070272)
0.1 0.4 GO:0033144 negative regulation of intracellular steroid hormone receptor signaling pathway(GO:0033144)
0.1 0.1 GO:0045617 negative regulation of keratinocyte differentiation(GO:0045617)
0.1 0.2 GO:0045197 establishment or maintenance of epithelial cell apical/basal polarity(GO:0045197)
0.1 0.1 GO:0051045 negative regulation of membrane protein ectodomain proteolysis(GO:0051045)
0.1 0.2 GO:0010891 negative regulation of sequestering of triglyceride(GO:0010891)
0.1 0.1 GO:0010761 fibroblast migration(GO:0010761)
0.1 0.2 GO:0040037 negative regulation of fibroblast growth factor receptor signaling pathway(GO:0040037)
0.1 0.1 GO:0046639 negative regulation of alpha-beta T cell differentiation(GO:0046639)
0.1 0.1 GO:0019886 antigen processing and presentation of exogenous peptide antigen via MHC class II(GO:0019886)
0.1 0.2 GO:0051124 synaptic growth at neuromuscular junction(GO:0051124)
0.1 0.1 GO:0033599 regulation of mammary gland epithelial cell proliferation(GO:0033599)
0.1 0.3 GO:0006703 estrogen biosynthetic process(GO:0006703)
0.1 0.2 GO:0071425 hematopoietic stem cell proliferation(GO:0071425)
0.1 0.2 GO:0070935 3'-UTR-mediated mRNA stabilization(GO:0070935)
0.1 0.2 GO:0007386 compartment pattern specification(GO:0007386)
0.1 0.3 GO:0048333 mesodermal cell fate commitment(GO:0001710) mesodermal cell differentiation(GO:0048333)
0.1 0.2 GO:0000712 resolution of meiotic recombination intermediates(GO:0000712) meiotic chromosome separation(GO:0051307)
0.1 0.2 GO:2000095 regulation of non-canonical Wnt signaling pathway(GO:2000050) regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000095)
0.1 0.2 GO:0045992 negative regulation of embryonic development(GO:0045992)
0.1 0.1 GO:0060435 bronchiole development(GO:0060435)
0.1 0.4 GO:0021772 olfactory bulb development(GO:0021772) olfactory lobe development(GO:0021988)
0.1 0.3 GO:0021952 central nervous system projection neuron axonogenesis(GO:0021952)
0.1 0.2 GO:0010701 positive regulation of norepinephrine secretion(GO:0010701)
0.1 0.3 GO:0007598 blood coagulation, extrinsic pathway(GO:0007598)
0.1 0.1 GO:0060242 contact inhibition(GO:0060242)
0.1 0.1 GO:0046512 diol biosynthetic process(GO:0034312) sphingosine biosynthetic process(GO:0046512)
0.1 1.3 GO:0048146 positive regulation of fibroblast proliferation(GO:0048146)
0.1 0.5 GO:0007520 syncytium formation by plasma membrane fusion(GO:0000768) myoblast fusion(GO:0007520)
0.1 0.2 GO:0071436 sodium ion export(GO:0071436)
0.1 0.2 GO:0006296 nucleotide-excision repair, DNA incision, 5'-to lesion(GO:0006296)
0.1 0.1 GO:0010757 negative regulation of plasminogen activation(GO:0010757)
0.1 0.2 GO:0006498 N-terminal protein lipidation(GO:0006498)
0.1 0.2 GO:0010225 response to UV-C(GO:0010225)
0.1 0.5 GO:0034446 substrate adhesion-dependent cell spreading(GO:0034446)
0.1 0.2 GO:0008354 germ cell migration(GO:0008354)
0.1 0.2 GO:0034720 histone H3-K4 demethylation(GO:0034720)
0.1 0.1 GO:0031946 regulation of glucocorticoid biosynthetic process(GO:0031946)
0.1 0.1 GO:0071502 cellular response to temperature stimulus(GO:0071502)
0.1 0.2 GO:0031536 positive regulation of exit from mitosis(GO:0031536)
0.0 0.2 GO:0006531 aspartate metabolic process(GO:0006531) aspartate catabolic process(GO:0006533)
0.0 0.1 GO:0043615 astrocyte cell migration(GO:0043615)
0.0 0.0 GO:0007144 female meiosis I(GO:0007144)
0.0 0.0 GO:0007638 mechanosensory behavior(GO:0007638)
0.0 0.1 GO:0010837 regulation of keratinocyte proliferation(GO:0010837)
0.0 0.1 GO:0008053 mitochondrial fusion(GO:0008053)
0.0 0.2 GO:0060013 righting reflex(GO:0060013)
0.0 0.2 GO:0045091 regulation of single stranded viral RNA replication via double stranded DNA intermediate(GO:0045091)
0.0 0.6 GO:0032964 collagen biosynthetic process(GO:0032964)
0.0 0.0 GO:0033145 positive regulation of intracellular steroid hormone receptor signaling pathway(GO:0033145)
0.0 0.0 GO:0033158 regulation of protein import into nucleus, translocation(GO:0033158)
0.0 0.2 GO:0048745 smooth muscle tissue development(GO:0048745)
0.0 0.3 GO:0008634 obsolete negative regulation of survival gene product expression(GO:0008634)
0.0 0.1 GO:0042483 negative regulation of odontogenesis(GO:0042483)
0.0 1.6 GO:0001843 neural tube closure(GO:0001843)
0.0 0.1 GO:0032354 response to follicle-stimulating hormone(GO:0032354)
0.0 0.1 GO:0033173 calcineurin-NFAT signaling cascade(GO:0033173)
0.0 0.0 GO:0072393 microtubule anchoring at microtubule organizing center(GO:0072393)
0.0 0.1 GO:0042726 flavin-containing compound metabolic process(GO:0042726)
0.0 0.2 GO:0007021 tubulin complex assembly(GO:0007021)
0.0 0.2 GO:0035434 copper ion transmembrane transport(GO:0035434)
0.0 0.1 GO:0051138 NK T cell differentiation(GO:0001865) regulation of NK T cell differentiation(GO:0051136) positive regulation of NK T cell differentiation(GO:0051138)
0.0 0.2 GO:0000730 DNA recombinase assembly(GO:0000730) double-strand break repair via synthesis-dependent strand annealing(GO:0045003)
0.0 0.1 GO:0014012 peripheral nervous system axon regeneration(GO:0014012)
0.0 0.2 GO:0042149 cellular response to glucose starvation(GO:0042149)
0.0 0.0 GO:0055098 response to low-density lipoprotein particle(GO:0055098)
0.0 0.2 GO:0033683 nucleotide-excision repair, DNA incision(GO:0033683)
0.0 0.0 GO:0070309 lens fiber cell morphogenesis(GO:0070309)
0.0 0.3 GO:0001974 blood vessel remodeling(GO:0001974)
0.0 0.0 GO:0010800 positive regulation of peptidyl-threonine phosphorylation(GO:0010800)
0.0 0.0 GO:0046874 quinolinate metabolic process(GO:0046874)
0.0 0.1 GO:0010842 retina layer formation(GO:0010842)
0.0 0.1 GO:0016999 antibiotic metabolic process(GO:0016999) antibiotic biosynthetic process(GO:0017000)
0.0 0.1 GO:0035609 C-terminal protein deglutamylation(GO:0035609) protein side chain deglutamylation(GO:0035610)
0.0 0.2 GO:0072526 pyridine-containing compound catabolic process(GO:0072526)
0.0 0.5 GO:0035329 hippo signaling(GO:0035329)
0.0 0.1 GO:0060083 smooth muscle contraction involved in micturition(GO:0060083)
0.0 0.2 GO:0006477 protein sulfation(GO:0006477)
0.0 0.2 GO:0048149 behavioral response to ethanol(GO:0048149)
0.0 0.1 GO:0048643 positive regulation of skeletal muscle tissue development(GO:0048643)
0.0 0.0 GO:0046940 nucleoside monophosphate phosphorylation(GO:0046940)
0.0 0.5 GO:0006972 hyperosmotic response(GO:0006972)
0.0 0.1 GO:0016241 regulation of macroautophagy(GO:0016241)
0.0 0.2 GO:0071027 RNA surveillance(GO:0071025) nuclear RNA surveillance(GO:0071027) nuclear mRNA surveillance(GO:0071028)
0.0 0.1 GO:0090399 replicative senescence(GO:0090399)
0.0 0.2 GO:0042753 positive regulation of circadian rhythm(GO:0042753)
0.0 0.2 GO:0007252 I-kappaB phosphorylation(GO:0007252)
0.0 0.2 GO:0046855 phosphorylated carbohydrate dephosphorylation(GO:0046838) inositol phosphate dephosphorylation(GO:0046855)
0.0 0.1 GO:0006307 DNA dealkylation involved in DNA repair(GO:0006307)
0.0 0.2 GO:0051593 response to folic acid(GO:0051593)
0.0 0.2 GO:0001514 selenocysteine incorporation(GO:0001514) translational readthrough(GO:0006451)
0.0 0.2 GO:0032020 ISG15-protein conjugation(GO:0032020)
0.0 0.1 GO:0048712 negative regulation of astrocyte differentiation(GO:0048712)
0.0 0.0 GO:0051926 negative regulation of calcium ion transport(GO:0051926)
0.0 0.2 GO:0014912 negative regulation of smooth muscle cell migration(GO:0014912)
0.0 0.2 GO:0015871 choline transport(GO:0015871)
0.0 0.3 GO:0043388 positive regulation of DNA binding(GO:0043388)
0.0 0.1 GO:0060736 prostate gland growth(GO:0060736)
0.0 0.1 GO:0046827 positive regulation of protein export from nucleus(GO:0046827)
0.0 0.7 GO:0050873 brown fat cell differentiation(GO:0050873)
0.0 0.0 GO:0007571 age-dependent response to oxidative stress(GO:0001306) age-dependent general metabolic decline(GO:0007571)
0.0 0.1 GO:0006422 aspartyl-tRNA aminoacylation(GO:0006422)
0.0 0.1 GO:0003283 atrial septum development(GO:0003283) atrial septum morphogenesis(GO:0060413)
0.0 0.2 GO:0043277 apoptotic cell clearance(GO:0043277)
0.0 0.4 GO:0019321 pentose metabolic process(GO:0019321)
0.0 0.2 GO:0050917 sensory perception of umami taste(GO:0050917)
0.0 0.3 GO:0009267 cellular response to starvation(GO:0009267)
0.0 0.2 GO:0051382 kinetochore assembly(GO:0051382)
0.0 0.1 GO:0051323 mitotic metaphase(GO:0000089) metaphase(GO:0051323)
0.0 0.3 GO:0045600 positive regulation of fat cell differentiation(GO:0045600)
0.0 0.1 GO:0060017 parathyroid gland development(GO:0060017)
0.0 0.1 GO:0071318 cellular response to ATP(GO:0071318)
0.0 0.8 GO:0006493 protein O-linked glycosylation(GO:0006493)
0.0 0.1 GO:2000178 negative regulation of neuroblast proliferation(GO:0007406) negative regulation of neural precursor cell proliferation(GO:2000178)
0.0 0.2 GO:0043537 negative regulation of blood vessel endothelial cell migration(GO:0043537)
0.0 0.1 GO:0033591 response to ozone(GO:0010193) response to L-ascorbic acid(GO:0033591)
0.0 0.1 GO:0031282 regulation of guanylate cyclase activity(GO:0031282)
0.0 0.2 GO:0048013 ephrin receptor signaling pathway(GO:0048013)
0.0 0.4 GO:0007128 meiotic prophase I(GO:0007128)
0.0 0.1 GO:0072383 plus-end-directed vesicle transport along microtubule(GO:0072383) plus-end-directed organelle transport along microtubule(GO:0072386)
0.0 0.1 GO:0007567 parturition(GO:0007567)
0.0 0.4 GO:0032008 positive regulation of TOR signaling(GO:0032008)
0.0 0.1 GO:0032455 nerve growth factor processing(GO:0032455)
0.0 0.1 GO:0045162 clustering of voltage-gated sodium channels(GO:0045162)
0.0 0.1 GO:0045792 negative regulation of cell size(GO:0045792)
0.0 0.0 GO:0060164 regulation of timing of neuron differentiation(GO:0060164)
0.0 0.0 GO:0033240 positive regulation of cellular amine metabolic process(GO:0033240)
0.0 0.1 GO:0006663 platelet activating factor biosynthetic process(GO:0006663)
0.0 0.2 GO:0006729 tetrahydrobiopterin biosynthetic process(GO:0006729)
0.0 0.2 GO:0061515 erythrocyte development(GO:0048821) myeloid cell development(GO:0061515)
0.0 0.1 GO:0015810 C4-dicarboxylate transport(GO:0015740) aspartate transport(GO:0015810)
0.0 0.1 GO:0001821 histamine secretion(GO:0001821)
0.0 0.2 GO:0006551 leucine metabolic process(GO:0006551)
0.0 0.2 GO:0010452 histone H3-K36 methylation(GO:0010452)
0.0 0.4 GO:0030865 cortical cytoskeleton organization(GO:0030865) cortical actin cytoskeleton organization(GO:0030866)
0.0 0.0 GO:0048319 axial mesoderm morphogenesis(GO:0048319)
0.0 0.1 GO:0007343 egg activation(GO:0007343)
0.0 0.1 GO:0005981 regulation of glycogen catabolic process(GO:0005981)
0.0 0.1 GO:0018206 peptidyl-methionine modification(GO:0018206)
0.0 0.1 GO:0007412 axon target recognition(GO:0007412)
0.0 0.2 GO:0043567 regulation of insulin-like growth factor receptor signaling pathway(GO:0043567)
0.0 0.1 GO:0042983 amyloid precursor protein biosynthetic process(GO:0042983) regulation of amyloid precursor protein biosynthetic process(GO:0042984)
0.0 0.1 GO:0090080 positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway(GO:0090080)
0.0 0.2 GO:0006578 amino-acid betaine biosynthetic process(GO:0006578) carnitine biosynthetic process(GO:0045329)
0.0 0.1 GO:0061302 smooth muscle cell-matrix adhesion(GO:0061302)
0.0 0.1 GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.0 0.0 GO:0048702 embryonic neurocranium morphogenesis(GO:0048702)
0.0 0.1 GO:0071043 CUT catabolic process(GO:0071034) CUT metabolic process(GO:0071043)
0.0 0.1 GO:0035376 sterol import(GO:0035376) cholesterol import(GO:0070508)
0.0 0.1 GO:0050955 thermoception(GO:0050955)
0.0 0.0 GO:0002887 negative regulation of myeloid leukocyte mediated immunity(GO:0002887) negative regulation of leukocyte degranulation(GO:0043301)
0.0 0.1 GO:0046599 regulation of centriole replication(GO:0046599)
0.0 0.1 GO:0019852 L-ascorbic acid metabolic process(GO:0019852)
0.0 0.5 GO:0019933 cAMP-mediated signaling(GO:0019933)
0.0 0.1 GO:0033146 regulation of intracellular estrogen receptor signaling pathway(GO:0033146)
0.0 0.2 GO:2000273 positive regulation of receptor activity(GO:2000273)
0.0 0.1 GO:0048251 elastic fiber assembly(GO:0048251)
0.0 0.1 GO:0070874 negative regulation of glycogen metabolic process(GO:0070874)
0.0 0.0 GO:0030185 nitric oxide transport(GO:0030185)
0.0 0.1 GO:0006048 UDP-N-acetylglucosamine biosynthetic process(GO:0006048)
0.0 0.1 GO:0090084 negative regulation of inclusion body assembly(GO:0090084)
0.0 0.1 GO:0030325 adrenal gland development(GO:0030325)
0.0 0.1 GO:0051967 negative regulation of synaptic transmission, glutamatergic(GO:0051967)
0.0 0.0 GO:0016048 detection of temperature stimulus(GO:0016048)
0.0 0.2 GO:0048385 regulation of retinoic acid receptor signaling pathway(GO:0048385)
0.0 0.0 GO:0060745 mammary gland branching involved in pregnancy(GO:0060745)
0.0 0.1 GO:0032069 regulation of nuclease activity(GO:0032069)
0.0 0.1 GO:0070389 chaperone cofactor-dependent protein refolding(GO:0070389)
0.0 0.1 GO:0055093 response to increased oxygen levels(GO:0036296) response to hyperoxia(GO:0055093)
0.0 0.1 GO:0046719 intracellular transport of viral protein in host cell(GO:0019060) symbiont intracellular protein transport in host(GO:0030581) regulation by virus of viral protein levels in host cell(GO:0046719) intracellular protein transport in other organism involved in symbiotic interaction(GO:0051708)
0.0 0.0 GO:0060527 prostate glandular acinus morphogenesis(GO:0060526) prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis(GO:0060527)
0.0 0.1 GO:0002069 columnar/cuboidal epithelial cell maturation(GO:0002069)
0.0 0.1 GO:0007199 G-protein coupled receptor signaling pathway coupled to cGMP nucleotide second messenger(GO:0007199)
0.0 0.1 GO:0060261 positive regulation of transcription initiation from RNA polymerase II promoter(GO:0060261) positive regulation of DNA-templated transcription, initiation(GO:2000144)
0.0 0.5 GO:0010811 positive regulation of cell-substrate adhesion(GO:0010811)
0.0 0.2 GO:0007220 Notch receptor processing(GO:0007220)
0.0 0.1 GO:0008347 glial cell migration(GO:0008347)
0.0 0.1 GO:0010591 regulation of lamellipodium assembly(GO:0010591)
0.0 0.1 GO:0048714 positive regulation of oligodendrocyte differentiation(GO:0048714)
0.0 0.1 GO:0034453 microtubule anchoring(GO:0034453)
0.0 0.1 GO:0034643 establishment of mitochondrion localization, microtubule-mediated(GO:0034643) mitochondrion transport along microtubule(GO:0047497)
0.0 0.1 GO:0002070 epithelial cell maturation(GO:0002070)
0.0 0.0 GO:0008300 isoprenoid catabolic process(GO:0008300)
0.0 0.1 GO:0030952 establishment or maintenance of cytoskeleton polarity(GO:0030952)
0.0 0.1 GO:0060740 prostate gland epithelium morphogenesis(GO:0060740)
0.0 0.0 GO:0046325 negative regulation of glucose transport(GO:0010829) negative regulation of glucose import(GO:0046325)
0.0 0.1 GO:0070584 mitochondrion morphogenesis(GO:0070584)
0.0 0.0 GO:0040015 negative regulation of multicellular organism growth(GO:0040015)
0.0 0.0 GO:1990845 diet induced thermogenesis(GO:0002024) adaptive thermogenesis(GO:1990845)
0.0 0.3 GO:0007029 endoplasmic reticulum organization(GO:0007029)
0.0 0.1 GO:0050774 negative regulation of dendrite morphogenesis(GO:0050774)
0.0 0.5 GO:0005978 glycogen biosynthetic process(GO:0005978) glucan biosynthetic process(GO:0009250)
0.0 0.2 GO:0008209 androgen metabolic process(GO:0008209)
0.0 0.2 GO:0006825 copper ion transport(GO:0006825)
0.0 0.0 GO:0010834 obsolete telomere maintenance via telomere shortening(GO:0010834)
0.0 0.0 GO:0001778 plasma membrane repair(GO:0001778)
0.0 0.2 GO:0042559 folic acid-containing compound biosynthetic process(GO:0009396) pteridine-containing compound biosynthetic process(GO:0042559)
0.0 0.1 GO:0035058 nonmotile primary cilium assembly(GO:0035058)
0.0 0.2 GO:0015884 folic acid transport(GO:0015884)
0.0 0.0 GO:0060999 positive regulation of dendritic spine development(GO:0060999)
0.0 0.3 GO:0021983 pituitary gland development(GO:0021983)
0.0 0.1 GO:0010792 DNA double-strand break processing involved in repair via single-strand annealing(GO:0010792) double-strand break repair via single-strand annealing(GO:0045002)
0.0 0.0 GO:0046520 sphingoid biosynthetic process(GO:0046520)
0.0 0.1 GO:0034694 response to prostaglandin(GO:0034694)
0.0 0.0 GO:0046825 regulation of protein export from nucleus(GO:0046825)
0.0 0.0 GO:0009786 regulation of asymmetric cell division(GO:0009786)
0.0 0.1 GO:0008045 motor neuron axon guidance(GO:0008045)
0.0 0.0 GO:0034441 plasma lipoprotein particle oxidation(GO:0034441) regulation of lipoprotein oxidation(GO:0034442) negative regulation of lipoprotein oxidation(GO:0034443) regulation of plasma lipoprotein particle oxidation(GO:0034444) negative regulation of plasma lipoprotein particle oxidation(GO:0034445) lipoprotein modification(GO:0042160) lipoprotein oxidation(GO:0042161)
0.0 0.1 GO:0001757 somite specification(GO:0001757)
0.0 0.1 GO:0000085 mitotic G2 phase(GO:0000085) G2 phase(GO:0051319)
0.0 0.1 GO:0035519 protein K29-linked ubiquitination(GO:0035519)
0.0 0.0 GO:0044321 cellular response to leptin stimulus(GO:0044320) response to leptin(GO:0044321)
0.0 0.2 GO:0006359 regulation of transcription from RNA polymerase III promoter(GO:0006359)
0.0 0.1 GO:0006930 substrate-dependent cell migration, cell extension(GO:0006930)
0.0 0.2 GO:0032456 endocytic recycling(GO:0032456)
0.0 0.0 GO:0014848 urinary bladder smooth muscle contraction(GO:0014832) urinary tract smooth muscle contraction(GO:0014848)
0.0 0.0 GO:0060068 vagina development(GO:0060068)
0.0 0.0 GO:0009191 nucleoside diphosphate catabolic process(GO:0009134) ribonucleoside diphosphate catabolic process(GO:0009191)
0.0 0.4 GO:0021987 cerebral cortex development(GO:0021987)
0.0 0.1 GO:0015889 cobalamin transport(GO:0015889)
0.0 0.1 GO:0046498 S-adenosylhomocysteine metabolic process(GO:0046498)
0.0 0.1 GO:0035455 response to interferon-alpha(GO:0035455)
0.0 0.1 GO:0010224 response to UV-B(GO:0010224)
0.0 0.2 GO:0006596 polyamine biosynthetic process(GO:0006596)
0.0 0.0 GO:0019614 phenol-containing compound catabolic process(GO:0019336) catechol-containing compound catabolic process(GO:0019614) catecholamine catabolic process(GO:0042424)
0.0 0.1 GO:0017187 peptidyl-glutamic acid carboxylation(GO:0017187) protein carboxylation(GO:0018214)
0.0 0.3 GO:0043631 RNA polyadenylation(GO:0043631)
0.0 0.4 GO:0006471 protein ADP-ribosylation(GO:0006471)
0.0 0.2 GO:0046626 regulation of insulin receptor signaling pathway(GO:0046626) regulation of cellular response to insulin stimulus(GO:1900076)
0.0 0.0 GO:0061525 hindgut morphogenesis(GO:0007442) hindgut development(GO:0061525)
0.0 0.1 GO:0015760 hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760)
0.0 0.1 GO:0006000 fructose metabolic process(GO:0006000)
0.0 0.1 GO:0001841 neural tube formation(GO:0001841)
0.0 0.1 GO:0032836 glomerular basement membrane development(GO:0032836)
0.0 0.0 GO:0034384 high-density lipoprotein particle clearance(GO:0034384)
0.0 0.1 GO:0045749 obsolete negative regulation of S phase of mitotic cell cycle(GO:0045749)
0.0 0.0 GO:0072177 mesonephric duct development(GO:0072177)
0.0 0.0 GO:0071397 cellular response to sterol(GO:0036315) cellular response to cholesterol(GO:0071397)
0.0 0.1 GO:0006559 L-phenylalanine metabolic process(GO:0006558) L-phenylalanine catabolic process(GO:0006559) erythrose 4-phosphate/phosphoenolpyruvate family amino acid metabolic process(GO:1902221) erythrose 4-phosphate/phosphoenolpyruvate family amino acid catabolic process(GO:1902222)
0.0 0.1 GO:0042797 5S class rRNA transcription from RNA polymerase III type 1 promoter(GO:0042791) tRNA transcription from RNA polymerase III promoter(GO:0042797)
0.0 0.1 GO:0007080 mitotic metaphase plate congression(GO:0007080) metaphase plate congression(GO:0051310)
0.0 0.0 GO:0042363 vitamin catabolic process(GO:0009111) fat-soluble vitamin catabolic process(GO:0042363)
0.0 0.1 GO:0007258 JUN phosphorylation(GO:0007258)
0.0 0.1 GO:0006654 phosphatidic acid biosynthetic process(GO:0006654)
0.0 0.1 GO:0015670 carbon dioxide transport(GO:0015670)
0.0 0.1 GO:0006929 substrate-dependent cell migration(GO:0006929)
0.0 0.1 GO:0048384 retinoic acid receptor signaling pathway(GO:0048384)
0.0 0.1 GO:0033131 regulation of glucokinase activity(GO:0033131) positive regulation of glucokinase activity(GO:0033133) regulation of hexokinase activity(GO:1903299) positive regulation of hexokinase activity(GO:1903301)
0.0 0.0 GO:0032717 negative regulation of interleukin-8 production(GO:0032717)
0.0 0.4 GO:0051318 G1 phase(GO:0051318)
0.0 0.0 GO:0032730 regulation of interleukin-1 alpha production(GO:0032650) positive regulation of interleukin-1 alpha production(GO:0032730)
0.0 0.2 GO:0000052 citrulline metabolic process(GO:0000052)
0.0 0.1 GO:0007549 dosage compensation(GO:0007549)
0.0 0.0 GO:0032060 bleb assembly(GO:0032060)
0.0 0.1 GO:0021903 rostrocaudal neural tube patterning(GO:0021903)
0.0 0.1 GO:0042574 retinal metabolic process(GO:0042574)
0.0 0.2 GO:0019184 nonribosomal peptide biosynthetic process(GO:0019184)
0.0 0.1 GO:0046688 response to copper ion(GO:0046688)
0.0 0.2 GO:0045806 negative regulation of endocytosis(GO:0045806)
0.0 0.0 GO:0090273 regulation of somatostatin secretion(GO:0090273)
0.0 0.1 GO:0006857 oligopeptide transport(GO:0006857)
0.0 0.1 GO:0051151 negative regulation of smooth muscle cell differentiation(GO:0051151)
0.0 0.3 GO:0018904 glycerol ether metabolic process(GO:0006662) ether metabolic process(GO:0018904)
0.0 0.2 GO:0046459 short-chain fatty acid metabolic process(GO:0046459)
0.0 0.1 GO:0007217 tachykinin receptor signaling pathway(GO:0007217)
0.0 0.0 GO:0045541 negative regulation of cholesterol biosynthetic process(GO:0045541) negative regulation of cholesterol metabolic process(GO:0090206)
0.0 0.2 GO:0006497 protein lipidation(GO:0006497)
0.0 0.1 GO:0061099 negative regulation of protein tyrosine kinase activity(GO:0061099)
0.0 0.1 GO:0045116 protein neddylation(GO:0045116)
0.0 0.1 GO:0048268 clathrin coat assembly(GO:0048268)
0.0 0.3 GO:0030574 collagen catabolic process(GO:0030574)
0.0 0.4 GO:0030262 apoptotic nuclear changes(GO:0030262)
0.0 0.1 GO:0006707 cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127)
0.0 0.1 GO:0046415 urate metabolic process(GO:0046415)
0.0 0.1 GO:0019367 fatty acid elongation, saturated fatty acid(GO:0019367)
0.0 0.0 GO:0001955 blood vessel maturation(GO:0001955)
0.0 0.2 GO:0015695 organic cation transport(GO:0015695)
0.0 0.2 GO:0051156 glucose 6-phosphate metabolic process(GO:0051156)
0.0 0.3 GO:0014047 glutamate secretion(GO:0014047)
0.0 0.0 GO:0090083 regulation of inclusion body assembly(GO:0090083)
0.0 0.2 GO:0018149 peptide cross-linking(GO:0018149)
0.0 0.0 GO:0060648 mammary gland bud morphogenesis(GO:0060648)
0.0 0.1 GO:0007528 neuromuscular junction development(GO:0007528)
0.0 0.0 GO:0051503 adenine nucleotide transport(GO:0051503)
0.0 0.2 GO:0006693 prostaglandin metabolic process(GO:0006693)
0.0 0.1 GO:0006817 phosphate ion transport(GO:0006817)
0.0 0.2 GO:0015949 nucleobase-containing small molecule interconversion(GO:0015949)
0.0 0.0 GO:0046349 amino sugar biosynthetic process(GO:0046349)
0.0 0.1 GO:0042693 muscle cell fate commitment(GO:0042693)
0.0 0.3 GO:0030261 chromosome condensation(GO:0030261)
0.0 0.1 GO:0000305 response to oxygen radical(GO:0000305)
0.0 0.0 GO:0097576 vacuole fusion(GO:0097576)
0.0 0.1 GO:0006448 regulation of translational elongation(GO:0006448)
0.0 0.0 GO:0052169 microglial cell activation involved in immune response(GO:0002282) pathogen-associated molecular pattern dependent induction by symbiont of host innate immune response(GO:0052033) positive regulation by symbiont of host innate immune response(GO:0052166) modulation by symbiont of host innate immune response(GO:0052167) pathogen-associated molecular pattern dependent modulation by symbiont of host innate immune response(GO:0052169) pathogen-associated molecular pattern dependent induction by organism of innate immune response of other organism involved in symbiotic interaction(GO:0052257) positive regulation by organism of innate immune response in other organism involved in symbiotic interaction(GO:0052305) modulation by organism of innate immune response in other organism involved in symbiotic interaction(GO:0052306) pathogen-associated molecular pattern dependent modulation by organism of innate immune response in other organism involved in symbiotic interaction(GO:0052308)
0.0 0.2 GO:0007340 acrosome reaction(GO:0007340)
0.0 0.2 GO:0070206 protein trimerization(GO:0070206)
0.0 0.0 GO:0048840 otolith development(GO:0048840)
0.0 0.2 GO:0042274 ribosomal small subunit biogenesis(GO:0042274)
0.0 0.0 GO:0071157 negative regulation of cell cycle arrest(GO:0071157)
0.0 0.1 GO:0051818 disruption of cells of other organism involved in symbiotic interaction(GO:0051818) killing of cells in other organism involved in symbiotic interaction(GO:0051883)
0.0 0.1 GO:0032757 positive regulation of interleukin-8 production(GO:0032757)
0.0 0.2 GO:0045740 positive regulation of DNA replication(GO:0045740)
0.0 0.1 GO:0045039 protein import into mitochondrial inner membrane(GO:0045039)
0.0 0.0 GO:0002220 innate immune response activating cell surface receptor signaling pathway(GO:0002220)
0.0 0.3 GO:0042744 hydrogen peroxide catabolic process(GO:0042744)
0.0 0.1 GO:0007494 midgut development(GO:0007494)
0.0 0.0 GO:0000103 sulfate assimilation(GO:0000103)
0.0 0.1 GO:0021569 rhombomere 3 development(GO:0021569)
0.0 0.1 GO:0046784 viral mRNA export from host cell nucleus(GO:0046784)
0.0 0.0 GO:0018200 peptidyl-glutamic acid modification(GO:0018200)
0.0 0.2 GO:0016998 cell wall macromolecule catabolic process(GO:0016998)
0.0 0.1 GO:0008228 opsonization(GO:0008228)
0.0 0.0 GO:0070050 neuron cellular homeostasis(GO:0070050)
0.0 0.0 GO:0016080 synaptic vesicle targeting(GO:0016080)
0.0 0.0 GO:0042339 keratan sulfate metabolic process(GO:0042339)
0.0 0.0 GO:0070254 mucus secretion(GO:0070254)
0.0 0.0 GO:0035751 lysosomal lumen acidification(GO:0007042) regulation of lysosomal lumen pH(GO:0035751)
0.0 0.0 GO:0009648 photoperiodism(GO:0009648)
0.0 0.0 GO:0090322 regulation of superoxide anion generation(GO:0032928) regulation of superoxide metabolic process(GO:0090322)
0.0 0.0 GO:0071569 protein ufmylation(GO:0071569)
0.0 0.1 GO:0006777 Mo-molybdopterin cofactor biosynthetic process(GO:0006777) Mo-molybdopterin cofactor metabolic process(GO:0019720) molybdopterin cofactor biosynthetic process(GO:0032324) molybdopterin cofactor metabolic process(GO:0043545) prosthetic group metabolic process(GO:0051189)
0.0 0.2 GO:0048010 vascular endothelial growth factor receptor signaling pathway(GO:0048010)
0.0 0.0 GO:0046541 saliva secretion(GO:0046541)
0.0 0.1 GO:0045351 type I interferon biosynthetic process(GO:0045351)
0.0 0.0 GO:0006651 diacylglycerol biosynthetic process(GO:0006651)
0.0 0.1 GO:0001561 fatty acid alpha-oxidation(GO:0001561)
0.0 0.1 GO:0043097 pyrimidine-containing compound salvage(GO:0008655) pyrimidine nucleoside salvage(GO:0043097)
0.0 0.4 GO:0042552 myelination(GO:0042552)
0.0 0.0 GO:0070244 negative regulation of thymocyte apoptotic process(GO:0070244)
0.0 0.0 GO:0003085 negative regulation of systemic arterial blood pressure(GO:0003085)
0.0 0.2 GO:0006699 bile acid biosynthetic process(GO:0006699)
0.0 0.1 GO:0046337 phosphatidylethanolamine biosynthetic process(GO:0006646) phosphatidylethanolamine metabolic process(GO:0046337)
0.0 0.0 GO:0045007 depurination(GO:0045007)
0.0 0.3 GO:0002088 lens development in camera-type eye(GO:0002088)
0.0 0.0 GO:0033605 positive regulation of catecholamine secretion(GO:0033605)
0.0 0.1 GO:0070076 histone lysine demethylation(GO:0070076)
0.0 0.1 GO:0046039 GTP metabolic process(GO:0046039)
0.0 0.0 GO:0043954 cellular component maintenance(GO:0043954)
0.0 0.0 GO:0042271 susceptibility to natural killer cell mediated cytotoxicity(GO:0042271)
0.0 0.0 GO:0006265 DNA topological change(GO:0006265)
0.0 0.0 GO:0006482 protein demethylation(GO:0006482) protein dealkylation(GO:0008214)
0.0 0.0 GO:0009415 response to water deprivation(GO:0009414) response to water(GO:0009415)
0.0 0.0 GO:0002281 macrophage activation involved in immune response(GO:0002281)
0.0 0.0 GO:0060023 soft palate development(GO:0060023)
0.0 0.0 GO:0051150 regulation of smooth muscle cell differentiation(GO:0051150)
0.0 0.1 GO:0001556 oocyte maturation(GO:0001556)
0.0 0.0 GO:0061245 establishment or maintenance of apical/basal cell polarity(GO:0035088) establishment or maintenance of bipolar cell polarity(GO:0061245)
0.0 1.1 GO:0042787 protein ubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0042787)
0.0 0.1 GO:0000718 nucleotide-excision repair, DNA damage removal(GO:0000718) DNA excision(GO:0044349)
0.0 0.0 GO:0021910 smoothened signaling pathway involved in ventral spinal cord patterning(GO:0021910)
0.0 0.0 GO:0006828 manganese ion transport(GO:0006828)
0.0 0.0 GO:0042158 lipoprotein biosynthetic process(GO:0042158)
0.0 0.0 GO:0051386 regulation of neurotrophin TRK receptor signaling pathway(GO:0051386)
0.0 0.0 GO:0043117 positive regulation of vascular permeability(GO:0043117)
0.0 0.1 GO:0007141 male meiosis I(GO:0007141)
0.0 0.0 GO:0060913 cardiac cell fate determination(GO:0060913)
0.0 0.0 GO:0044058 regulation of digestive system process(GO:0044058)
0.0 0.0 GO:0042637 catagen(GO:0042637)
0.0 0.1 GO:0015939 pantothenate metabolic process(GO:0015939)
0.0 0.0 GO:0060394 negative regulation of pathway-restricted SMAD protein phosphorylation(GO:0060394)
0.0 0.0 GO:0033622 integrin activation(GO:0033622)
0.0 0.0 GO:0032776 DNA methylation on cytosine(GO:0032776) C-5 methylation of cytosine(GO:0090116)
0.0 0.1 GO:0043526 obsolete neuroprotection(GO:0043526)
0.0 0.0 GO:0061101 neuroendocrine cell differentiation(GO:0061101)
0.0 0.1 GO:0016255 attachment of GPI anchor to protein(GO:0016255)
0.0 0.0 GO:0019985 translesion synthesis(GO:0019985)
0.0 0.0 GO:0033314 mitotic DNA replication checkpoint(GO:0033314)
0.0 0.0 GO:0050919 negative chemotaxis(GO:0050919)
0.0 0.3 GO:0006661 phosphatidylinositol biosynthetic process(GO:0006661)
0.0 0.6 GO:0006865 amino acid transport(GO:0006865)
0.0 0.0 GO:0021563 glossopharyngeal nerve development(GO:0021563) glossopharyngeal nerve morphogenesis(GO:0021615)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 GO:0031932 TORC2 complex(GO:0031932)
0.2 1.1 GO:0030056 hemidesmosome(GO:0030056)
0.2 0.2 GO:0071664 catenin-TCF7L2 complex(GO:0071664)
0.2 0.7 GO:0033268 node of Ranvier(GO:0033268)
0.2 0.8 GO:0005828 kinetochore microtubule(GO:0005828)
0.1 0.6 GO:0017059 palmitoyltransferase complex(GO:0002178) serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211)
0.1 1.1 GO:0008091 spectrin(GO:0008091)
0.1 0.4 GO:0042272 nuclear RNA export factor complex(GO:0042272)
0.1 0.4 GO:0070552 BRISC complex(GO:0070552)
0.1 0.3 GO:0001940 male pronucleus(GO:0001940)
0.1 0.3 GO:0005945 6-phosphofructokinase complex(GO:0005945)
0.1 0.5 GO:0031512 motile primary cilium(GO:0031512)
0.1 0.3 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.1 0.5 GO:0002102 podosome(GO:0002102)
0.1 0.2 GO:0043260 laminin-11 complex(GO:0043260)
0.1 0.3 GO:0005678 obsolete chromatin assembly complex(GO:0005678)
0.1 0.2 GO:0000176 nuclear exosome (RNase complex)(GO:0000176)
0.1 0.1 GO:0045298 tubulin complex(GO:0045298)
0.1 0.9 GO:0030132 clathrin coat of coated pit(GO:0030132)
0.1 0.3 GO:0070937 CRD-mediated mRNA stability complex(GO:0070937)
0.1 0.2 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.1 0.4 GO:0051233 spindle midzone(GO:0051233)
0.1 0.4 GO:0071778 obsolete WINAC complex(GO:0071778)
0.1 0.5 GO:0008385 IkappaB kinase complex(GO:0008385)
0.1 2.0 GO:0005884 actin filament(GO:0005884)
0.1 0.7 GO:0009925 basal plasma membrane(GO:0009925)
0.1 0.1 GO:0043083 synaptic cleft(GO:0043083)
0.1 0.5 GO:0043205 fibril(GO:0043205)
0.1 0.2 GO:0048179 activin receptor complex(GO:0048179)
0.1 0.2 GO:0036454 insulin-like growth factor binding protein complex(GO:0016942) growth factor complex(GO:0036454)
0.1 0.2 GO:0098647 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.1 0.4 GO:0005577 fibrinogen complex(GO:0005577)
0.1 0.5 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0 0.1 GO:0045178 basal part of cell(GO:0045178)
0.0 0.3 GO:0005851 eukaryotic translation initiation factor 2B complex(GO:0005851)
0.0 0.4 GO:0016580 Sin3 complex(GO:0016580) Sin3-type complex(GO:0070822)
0.0 0.1 GO:0032809 neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.0 0.3 GO:0098645 network-forming collagen trimer(GO:0098642) collagen network(GO:0098645)
0.0 0.2 GO:0071817 MMXD complex(GO:0071817)
0.0 0.1 GO:0033643 host(GO:0018995) host cell part(GO:0033643) host intracellular part(GO:0033646) intracellular region of host(GO:0043656) host cell(GO:0043657) other organism(GO:0044215) other organism cell(GO:0044216) other organism part(GO:0044217)
0.0 0.1 GO:0060200 clathrin-sculpted acetylcholine transport vesicle(GO:0060200) clathrin-sculpted acetylcholine transport vesicle membrane(GO:0060201)
0.0 0.1 GO:0070062 extracellular organelle(GO:0043230) extracellular exosome(GO:0070062) extracellular vesicle(GO:1903561)
0.0 0.0 GO:0043034 costamere(GO:0043034)
0.0 0.2 GO:0000138 Golgi trans cisterna(GO:0000138)
0.0 0.1 GO:0031527 filopodium membrane(GO:0031527)
0.0 0.4 GO:0030315 T-tubule(GO:0030315)
0.0 0.2 GO:0000445 THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.0 0.2 GO:0005885 Arp2/3 protein complex(GO:0005885)
0.0 0.9 GO:0005902 microvillus(GO:0005902)
0.0 0.2 GO:0005862 muscle thin filament tropomyosin(GO:0005862)
0.0 0.7 GO:0005811 lipid particle(GO:0005811)
0.0 0.1 GO:0005787 signal peptidase complex(GO:0005787)
0.0 1.0 GO:0030018 Z disc(GO:0030018)
0.0 0.2 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.0 0.1 GO:0071256 Sec61 translocon complex(GO:0005784) translocon complex(GO:0071256)
0.0 0.2 GO:0042598 obsolete vesicular fraction(GO:0042598)
0.0 0.0 GO:0001939 female pronucleus(GO:0001939)
0.0 0.3 GO:0043202 lysosomal lumen(GO:0043202)
0.0 0.2 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
0.0 1.5 GO:0030427 site of polarized growth(GO:0030427)
0.0 0.2 GO:0005832 chaperonin-containing T-complex(GO:0005832)
0.0 0.3 GO:0031233 intrinsic component of external side of plasma membrane(GO:0031233)
0.0 0.3 GO:0000780 condensed nuclear chromosome, centromeric region(GO:0000780)
0.0 0.2 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.0 1.8 GO:0030176 integral component of endoplasmic reticulum membrane(GO:0030176)
0.0 0.3 GO:0098643 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.0 0.4 GO:0000930 gamma-tubulin complex(GO:0000930)
0.0 0.2 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.0 0.5 GO:0045335 phagocytic vesicle(GO:0045335)
0.0 0.9 GO:0005905 clathrin-coated pit(GO:0005905)
0.0 2.0 GO:0099572 postsynaptic density(GO:0014069) postsynaptic specialization(GO:0099572)
0.0 0.0 GO:0042719 mitochondrial intermembrane space protein transporter complex(GO:0042719)
0.0 0.2 GO:0034464 BBSome(GO:0034464)
0.0 0.1 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.0 3.8 GO:0005912 adherens junction(GO:0005912)
0.0 0.1 GO:0070852 cell body fiber(GO:0070852)
0.0 0.1 GO:0016461 unconventional myosin complex(GO:0016461)
0.0 0.1 GO:0045273 mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)(GO:0005749) succinate dehydrogenase complex (ubiquinone)(GO:0045257) respiratory chain complex II(GO:0045273) succinate dehydrogenase complex(GO:0045281) fumarate reductase complex(GO:0045283)
0.0 0.3 GO:0001917 photoreceptor inner segment(GO:0001917)
0.0 0.0 GO:0034673 inhibin-betaglycan-ActRII complex(GO:0034673)
0.0 0.1 GO:0005652 nuclear lamina(GO:0005652)
0.0 0.0 GO:0071062 alphav-beta3 integrin-vitronectin complex(GO:0071062)
0.0 0.2 GO:0030677 nucleolar ribonuclease P complex(GO:0005655) ribonuclease P complex(GO:0030677) multimeric ribonuclease P complex(GO:0030681)
0.0 0.1 GO:0001520 outer dense fiber(GO:0001520) sperm flagellum(GO:0036126)
0.0 0.3 GO:0090665 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.0 0.2 GO:0042575 DNA polymerase complex(GO:0042575)
0.0 0.2 GO:0032838 cell projection cytoplasm(GO:0032838)
0.0 0.0 GO:0038201 TORC1 complex(GO:0031931) TOR complex(GO:0038201)
0.0 0.1 GO:0010369 chromocenter(GO:0010369)
0.0 0.6 GO:0042734 presynaptic membrane(GO:0042734)
0.0 0.1 GO:0008537 proteasome activator complex(GO:0008537)
0.0 0.4 GO:0005771 multivesicular body(GO:0005771)
0.0 0.1 GO:0000124 SAGA complex(GO:0000124)
0.0 0.1 GO:0043256 laminin complex(GO:0043256)
0.0 1.0 GO:0030496 midbody(GO:0030496)
0.0 0.2 GO:0000178 exosome (RNase complex)(GO:0000178)
0.0 0.2 GO:0005675 holo TFIIH complex(GO:0005675)
0.0 0.2 GO:0005744 mitochondrial inner membrane presequence translocase complex(GO:0005744)
0.0 0.6 GO:0016592 mediator complex(GO:0016592)
0.0 0.2 GO:0008278 cohesin complex(GO:0008278)
0.0 0.1 GO:0000109 nucleotide-excision repair complex(GO:0000109)
0.0 0.1 GO:0000127 transcription factor TFIIIC complex(GO:0000127)
0.0 0.1 GO:0005672 transcription factor TFIIA complex(GO:0005672)
0.0 0.2 GO:0032391 photoreceptor connecting cilium(GO:0032391)
0.0 0.1 GO:0033180 proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.0 0.2 GO:0017119 Golgi transport complex(GO:0017119)
0.0 0.3 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.0 0.1 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.0 0.0 GO:0032421 stereocilium bundle(GO:0032421)
0.0 0.1 GO:0042788 polysomal ribosome(GO:0042788)
0.0 3.8 GO:0005578 proteinaceous extracellular matrix(GO:0005578)
0.0 0.1 GO:0045275 mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
0.0 0.2 GO:0032420 stereocilium(GO:0032420)
0.0 0.1 GO:0005614 interstitial matrix(GO:0005614)
0.0 0.2 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.0 0.2 GO:0005581 collagen trimer(GO:0005581)
0.0 0.3 GO:0005796 Golgi lumen(GO:0005796)
0.0 0.1 GO:0042587 glycogen granule(GO:0042587)
0.0 0.0 GO:0031933 telomeric heterochromatin(GO:0031933)
0.0 0.0 GO:0031262 Ndc80 complex(GO:0031262)
0.0 0.1 GO:0033011 perinuclear theca(GO:0033011)
0.0 0.3 GO:0030134 ER to Golgi transport vesicle(GO:0030134)
0.0 0.2 GO:0016235 aggresome(GO:0016235)
0.0 0.1 GO:0030904 retromer complex(GO:0030904)
0.0 0.3 GO:0031519 PcG protein complex(GO:0031519)
0.0 0.1 GO:0033018 sarcoplasmic reticulum lumen(GO:0033018)
0.0 0.1 GO:0030867 rough endoplasmic reticulum membrane(GO:0030867)
0.0 0.8 GO:0005923 bicellular tight junction(GO:0005923) occluding junction(GO:0070160)
0.0 1.2 GO:0045095 keratin filament(GO:0045095)
0.0 0.3 GO:0005680 anaphase-promoting complex(GO:0005680)
0.0 0.0 GO:0000800 lateral element(GO:0000800)
0.0 0.3 GO:0034704 calcium channel complex(GO:0034704)
0.0 0.1 GO:0032156 septin complex(GO:0031105) septin cytoskeleton(GO:0032156)
0.0 0.2 GO:0031513 nonmotile primary cilium(GO:0031513)
0.0 0.1 GO:0031232 extrinsic component of external side of plasma membrane(GO:0031232)
0.0 0.0 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
0.0 0.0 GO:0005775 vacuolar lumen(GO:0005775)
0.0 0.1 GO:0000795 synaptonemal complex(GO:0000795)
0.0 0.3 GO:0000118 histone deacetylase complex(GO:0000118)
0.0 0.2 GO:0017053 transcriptional repressor complex(GO:0017053)
0.0 0.1 GO:0000796 condensin complex(GO:0000796)
0.0 0.8 GO:0005911 cell-cell junction(GO:0005911)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 1.7 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.2 0.9 GO:0004597 peptide-aspartate beta-dioxygenase activity(GO:0004597)
0.2 0.7 GO:0004758 serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
0.2 2.1 GO:0051010 microtubule plus-end binding(GO:0051010)
0.2 0.6 GO:0034186 apolipoprotein A-I binding(GO:0034186)
0.2 0.7 GO:0030297 transmembrane receptor protein tyrosine kinase activator activity(GO:0030297)
0.2 0.7 GO:0005010 insulin-like growth factor-activated receptor activity(GO:0005010)
0.2 0.9 GO:0042805 actinin binding(GO:0042805)
0.2 0.7 GO:0000293 ferric-chelate reductase activity(GO:0000293)
0.2 0.5 GO:0042799 histone methyltransferase activity (H4-K20 specific)(GO:0042799)
0.2 1.1 GO:0004908 interleukin-1 receptor activity(GO:0004908)
0.2 0.5 GO:0005006 epidermal growth factor-activated receptor activity(GO:0005006)
0.2 0.5 GO:0008321 Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.1 0.6 GO:0004430 1-phosphatidylinositol 4-kinase activity(GO:0004430)
0.1 0.6 GO:0004470 malic enzyme activity(GO:0004470)
0.1 0.7 GO:0004904 interferon receptor activity(GO:0004904)
0.1 0.4 GO:0005294 neutral L-amino acid secondary active transmembrane transporter activity(GO:0005294)
0.1 1.1 GO:0005021 vascular endothelial growth factor-activated receptor activity(GO:0005021)
0.1 0.1 GO:0008109 N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109)
0.1 0.5 GO:0048027 mRNA 5'-UTR binding(GO:0048027)
0.1 0.6 GO:0004749 ribose phosphate diphosphokinase activity(GO:0004749)
0.1 0.4 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.1 0.4 GO:0008502 melatonin receptor activity(GO:0008502)
0.1 0.3 GO:0033743 peptide-methionine (R)-S-oxide reductase activity(GO:0033743)
0.1 0.8 GO:0005110 frizzled-2 binding(GO:0005110)
0.1 0.3 GO:0070643 vitamin D3 25-hydroxylase activity(GO:0030343) vitamin D 25-hydroxylase activity(GO:0070643)
0.1 0.3 GO:0000987 RNA polymerase II core promoter proximal region sequence-specific DNA binding(GO:0000978) core promoter proximal region sequence-specific DNA binding(GO:0000987) core promoter proximal region DNA binding(GO:0001159)
0.1 0.3 GO:0017128 phospholipid scramblase activity(GO:0017128)
0.1 0.3 GO:0004720 protein-lysine 6-oxidase activity(GO:0004720)
0.1 0.3 GO:0033130 acetylcholine receptor binding(GO:0033130)
0.1 0.2 GO:0046975 histone methyltransferase activity (H3-K36 specific)(GO:0046975)
0.1 0.6 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.1 0.3 GO:0070052 collagen V binding(GO:0070052)
0.1 0.9 GO:0070717 poly-purine tract binding(GO:0070717)
0.1 0.3 GO:0003872 6-phosphofructokinase activity(GO:0003872)
0.1 0.5 GO:0044548 S100 protein binding(GO:0044548)
0.1 0.3 GO:0050544 arachidonic acid binding(GO:0050544)
0.1 0.3 GO:0003680 AT DNA binding(GO:0003680)
0.1 0.3 GO:0030215 semaphorin receptor binding(GO:0030215)
0.1 0.3 GO:0004829 threonine-tRNA ligase activity(GO:0004829)
0.1 0.5 GO:0005499 vitamin D binding(GO:0005499)
0.1 0.8 GO:0043395 heparan sulfate proteoglycan binding(GO:0043395)
0.1 0.4 GO:0030618 transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity(GO:0030618)
0.1 0.4 GO:0004528 phosphodiesterase I activity(GO:0004528)
0.1 0.6 GO:0017166 vinculin binding(GO:0017166)
0.1 0.3 GO:0004849 uridine kinase activity(GO:0004849)
0.1 0.3 GO:0005432 calcium:sodium antiporter activity(GO:0005432)
0.1 0.3 GO:0004157 dihydropyrimidinase activity(GO:0004157)
0.1 0.2 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.1 0.8 GO:0016641 oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor(GO:0016641)
0.1 1.1 GO:0005523 tropomyosin binding(GO:0005523)
0.1 0.2 GO:0050682 AF-2 domain binding(GO:0050682)
0.1 0.8 GO:0004859 phospholipase inhibitor activity(GO:0004859)
0.1 0.3 GO:0047429 nucleoside-triphosphate diphosphatase activity(GO:0047429)
0.1 0.4 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
0.1 0.5 GO:0000339 RNA cap binding(GO:0000339)
0.1 0.2 GO:0004117 calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117)
0.1 0.2 GO:0035514 DNA demethylase activity(GO:0035514) DNA-N1-methyladenine dioxygenase activity(GO:0043734)
0.1 0.2 GO:0002162 dystroglycan binding(GO:0002162)
0.1 0.6 GO:0005149 interleukin-1 receptor binding(GO:0005149)
0.1 0.3 GO:0003956 NAD(P)+-protein-arginine ADP-ribosyltransferase activity(GO:0003956)
0.1 0.2 GO:0003829 beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity(GO:0003829)
0.1 0.2 GO:0004948 calcitonin receptor activity(GO:0004948)
0.1 0.5 GO:0050786 RAGE receptor binding(GO:0050786)
0.1 0.6 GO:0005112 Notch binding(GO:0005112)
0.1 0.3 GO:0004645 phosphorylase activity(GO:0004645)
0.1 0.3 GO:0031995 insulin-like growth factor II binding(GO:0031995)
0.1 0.4 GO:0008046 axon guidance receptor activity(GO:0008046)
0.1 0.4 GO:0044390 ubiquitin conjugating enzyme binding(GO:0031624) ubiquitin-like protein conjugating enzyme binding(GO:0044390)
0.1 0.4 GO:0008035 high-density lipoprotein particle binding(GO:0008035)
0.1 0.3 GO:0050897 cobalt ion binding(GO:0050897)
0.1 0.1 GO:0070061 fructose binding(GO:0070061)
0.1 0.3 GO:0043522 leucine zipper domain binding(GO:0043522)
0.1 0.4 GO:0017080 sodium channel regulator activity(GO:0017080)
0.1 0.4 GO:0005114 type II transforming growth factor beta receptor binding(GO:0005114)
0.1 0.6 GO:0048185 activin binding(GO:0048185)
0.1 0.2 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.1 0.2 GO:0016715 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen(GO:0016715)
0.1 0.2 GO:0042978 ornithine decarboxylase activator activity(GO:0042978)
0.1 0.5 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.1 0.3 GO:0009374 biotin binding(GO:0009374)
0.1 0.5 GO:0003706 obsolete ligand-regulated transcription factor activity(GO:0003706)
0.1 0.3 GO:0030507 spectrin binding(GO:0030507)
0.1 0.2 GO:0003708 retinoic acid receptor activity(GO:0003708)
0.1 0.2 GO:0015016 [heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
0.1 0.3 GO:0016832 aldehyde-lyase activity(GO:0016832)
0.1 0.1 GO:0016509 long-chain-3-hydroxyacyl-CoA dehydrogenase activity(GO:0016509)
0.1 0.2 GO:0045545 syndecan binding(GO:0045545)
0.1 0.2 GO:0005105 type 1 fibroblast growth factor receptor binding(GO:0005105)
0.1 0.2 GO:0030292 protein tyrosine kinase inhibitor activity(GO:0030292)
0.1 0.2 GO:0005030 neurotrophin receptor activity(GO:0005030)
0.1 0.2 GO:0017089 glycolipid transporter activity(GO:0017089)
0.1 0.5 GO:0051019 mitogen-activated protein kinase binding(GO:0051019)
0.1 0.6 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)
0.1 0.2 GO:0016724 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.1 0.2 GO:0004716 receptor signaling protein tyrosine kinase activity(GO:0004716)
0.1 0.4 GO:0005522 profilin binding(GO:0005522)
0.1 0.2 GO:0032453 histone demethylase activity (H3-K4 specific)(GO:0032453) histone demethylase activity (H3-dimethyl-K4 specific)(GO:0034648)
0.1 0.2 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.1 0.8 GO:0008353 RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.0 0.1 GO:0008934 inositol monophosphate 1-phosphatase activity(GO:0008934) inositol monophosphate phosphatase activity(GO:0052834)
0.0 0.1 GO:0061731 ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
0.0 0.0 GO:1901567 icosanoid binding(GO:0050542) fatty acid derivative binding(GO:1901567)
0.0 0.2 GO:0050998 nitric-oxide synthase binding(GO:0050998)
0.0 0.9 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.0 0.2 GO:0017154 semaphorin receptor activity(GO:0017154)
0.0 0.2 GO:0005314 high-affinity glutamate transmembrane transporter activity(GO:0005314)
0.0 0.3 GO:0070513 death domain binding(GO:0070513)
0.0 0.2 GO:0000828 inositol hexakisphosphate kinase activity(GO:0000828) inositol hexakisphosphate 5-kinase activity(GO:0000832)
0.0 0.2 GO:0050510 N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity(GO:0050510)
0.0 0.1 GO:0070996 type 1 melanocortin receptor binding(GO:0070996)
0.0 0.1 GO:0005415 nucleoside:sodium symporter activity(GO:0005415)
0.0 0.0 GO:0031957 very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.0 0.3 GO:0005172 vascular endothelial growth factor receptor binding(GO:0005172)
0.0 0.1 GO:0004937 alpha1-adrenergic receptor activity(GO:0004937)
0.0 0.7 GO:1905030 voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
0.0 0.1 GO:0004505 phenylalanine 4-monooxygenase activity(GO:0004505)
0.0 0.1 GO:0048495 Roundabout binding(GO:0048495)
0.0 0.4 GO:0004428 obsolete inositol or phosphatidylinositol kinase activity(GO:0004428)
0.0 0.1 GO:0016312 inositol bisphosphate phosphatase activity(GO:0016312)
0.0 0.2 GO:0001846 opsonin binding(GO:0001846)
0.0 0.0 GO:0031994 insulin-like growth factor I binding(GO:0031994)
0.0 0.1 GO:0004045 aminoacyl-tRNA hydrolase activity(GO:0004045)
0.0 0.1 GO:0000268 peroxisome targeting sequence binding(GO:0000268)
0.0 0.1 GO:0016623 oxidoreductase activity, acting on the aldehyde or oxo group of donors, oxygen as acceptor(GO:0016623)
0.0 0.1 GO:0003896 DNA primase activity(GO:0003896)
0.0 0.2 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0 0.4 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.0 0.2 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.0 0.1 GO:0019966 interleukin-1 binding(GO:0019966)
0.0 0.2 GO:0004661 protein geranylgeranyltransferase activity(GO:0004661)
0.0 0.3 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.0 0.0 GO:0005017 platelet-derived growth factor-activated receptor activity(GO:0005017)
0.0 0.2 GO:0050656 3'-phosphoadenosine 5'-phosphosulfate binding(GO:0050656)
0.0 0.2 GO:0019238 cyclohydrolase activity(GO:0019238)
0.0 0.2 GO:0070700 BMP receptor binding(GO:0070700)
0.0 0.7 GO:0016505 peptidase activator activity involved in apoptotic process(GO:0016505)
0.0 0.1 GO:0008174 mRNA methyltransferase activity(GO:0008174)
0.0 0.2 GO:0008607 phosphorylase kinase regulator activity(GO:0008607)
0.0 0.1 GO:0019959 C-X-C chemokine binding(GO:0019958) interleukin-8 binding(GO:0019959)
0.0 0.2 GO:0015220 choline transmembrane transporter activity(GO:0015220)
0.0 0.6 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.0 0.1 GO:0033765 steroid dehydrogenase activity, acting on the CH-CH group of donors(GO:0033765)
0.0 0.1 GO:0004815 aspartate-tRNA ligase activity(GO:0004815)
0.0 0.1 GO:0052659 inositol-1,4,5-trisphosphate 5-phosphatase activity(GO:0052658) inositol-1,3,4,5-tetrakisphosphate 5-phosphatase activity(GO:0052659)
0.0 0.5 GO:0000175 3'-5'-exoribonuclease activity(GO:0000175)
0.0 0.6 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.0 0.1 GO:0001515 opioid peptide activity(GO:0001515)
0.0 0.1 GO:0005275 amine transmembrane transporter activity(GO:0005275)
0.0 0.1 GO:0047184 1-acylglycerophosphocholine O-acyltransferase activity(GO:0047184)
0.0 0.1 GO:0016530 metallochaperone activity(GO:0016530) copper chaperone activity(GO:0016531)
0.0 0.3 GO:0019992 diacylglycerol binding(GO:0019992)
0.0 0.2 GO:0017040 ceramidase activity(GO:0017040)
0.0 0.2 GO:0000405 bubble DNA binding(GO:0000405)
0.0 0.1 GO:0050501 hyaluronan synthase activity(GO:0050501)
0.0 0.5 GO:0005520 insulin-like growth factor binding(GO:0005520)
0.0 0.2 GO:0000014 single-stranded DNA endodeoxyribonuclease activity(GO:0000014)
0.0 0.4 GO:0042301 phosphate ion binding(GO:0042301)
0.0 0.7 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.0 0.2 GO:0004791 thioredoxin-disulfide reductase activity(GO:0004791)
0.0 0.1 GO:0000900 translation repressor activity, nucleic acid binding(GO:0000900)
0.0 0.6 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.0 0.2 GO:0034416 bisphosphoglycerate phosphatase activity(GO:0034416)
0.0 0.1 GO:0004340 glucokinase activity(GO:0004340)
0.0 0.1 GO:0016615 malate dehydrogenase activity(GO:0016615)
0.0 0.2 GO:0004303 estradiol 17-beta-dehydrogenase activity(GO:0004303)
0.0 0.1 GO:0004768 stearoyl-CoA 9-desaturase activity(GO:0004768) acyl-CoA desaturase activity(GO:0016215)
0.0 0.4 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.0 0.1 GO:0035198 miRNA binding(GO:0035198)
0.0 0.4 GO:0005355 glucose transmembrane transporter activity(GO:0005355)
0.0 0.3 GO:0048038 quinone binding(GO:0048038)
0.0 0.3 GO:0043236 laminin binding(GO:0043236)
0.0 0.1 GO:0032552 deoxyribonucleotide binding(GO:0032552) purine deoxyribonucleotide binding(GO:0032554) adenyl deoxyribonucleotide binding(GO:0032558)
0.0 0.0 GO:0016671 oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor(GO:0016671)
0.0 0.7 GO:0004364 glutathione transferase activity(GO:0004364)
0.0 0.1 GO:0015254 glycerol channel activity(GO:0015254)
0.0 0.1 GO:1901474 azole transporter activity(GO:0045118) azole transmembrane transporter activity(GO:1901474)
0.0 0.1 GO:0004064 arylesterase activity(GO:0004064)
0.0 0.2 GO:0003988 acetyl-CoA C-acyltransferase activity(GO:0003988)
0.0 0.1 GO:0008517 folic acid transporter activity(GO:0008517)
0.0 0.1 GO:0047631 ADP-ribose diphosphatase activity(GO:0047631)
0.0 0.2 GO:0034235 GPI anchor binding(GO:0034235)
0.0 0.1 GO:0046912 transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
0.0 0.2 GO:0004887 thyroid hormone receptor activity(GO:0004887)
0.0 0.7 GO:0019003 GDP binding(GO:0019003)
0.0 0.1 GO:0035242 protein-arginine omega-N asymmetric methyltransferase activity(GO:0035242)
0.0 0.1 GO:0019788 NEDD8 transferase activity(GO:0019788)
0.0 0.6 GO:0031683 G-protein beta/gamma-subunit complex binding(GO:0031683)
0.0 0.1 GO:0004977 melanocortin receptor activity(GO:0004977)
0.0 0.1 GO:0050815 phosphoserine binding(GO:0050815)
0.0 0.1 GO:0005000 vasopressin receptor activity(GO:0005000)
0.0 0.6 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.0 0.2 GO:0008198 ferrous iron binding(GO:0008198)
0.0 0.2 GO:0005372 water transmembrane transporter activity(GO:0005372)
0.0 0.1 GO:0050220 prostaglandin-E synthase activity(GO:0050220)
0.0 0.2 GO:0050840 extracellular matrix binding(GO:0050840)
0.0 0.1 GO:0004939 beta-adrenergic receptor activity(GO:0004939)
0.0 0.4 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.0 0.2 GO:0047035 testosterone dehydrogenase (NAD+) activity(GO:0047035)
0.0 0.1 GO:0016909 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.0 0.1 GO:0004784 superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
0.0 0.1 GO:0003846 2-acylglycerol O-acyltransferase activity(GO:0003846)
0.0 0.2 GO:0048019 receptor antagonist activity(GO:0048019)
0.0 0.0 GO:0015183 L-aspartate transmembrane transporter activity(GO:0015183)
0.0 0.1 GO:0016595 glutamate binding(GO:0016595)
0.0 0.4 GO:0022884 macromolecule transmembrane transporter activity(GO:0022884)
0.0 0.1 GO:0004300 enoyl-CoA hydratase activity(GO:0004300)
0.0 0.1 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.0 0.1 GO:0004802 transketolase activity(GO:0004802)
0.0 0.1 GO:0019855 calcium channel inhibitor activity(GO:0019855)
0.0 0.1 GO:0003987 acetate-CoA ligase activity(GO:0003987)
0.0 0.1 GO:0030492 hemoglobin binding(GO:0030492)
0.0 0.2 GO:0050811 GABA receptor binding(GO:0050811)
0.0 0.1 GO:0004800 thyroxine 5'-deiodinase activity(GO:0004800)
0.0 0.1 GO:0031702 type 1 angiotensin receptor binding(GO:0031702)
0.0 0.1 GO:0004457 lactate dehydrogenase activity(GO:0004457)
0.0 0.1 GO:0016303 1-phosphatidylinositol-3-kinase activity(GO:0016303)
0.0 0.1 GO:0070290 N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.0 0.1 GO:0030346 protein phosphatase 2B binding(GO:0030346)
0.0 0.1 GO:0015037 peptide disulfide oxidoreductase activity(GO:0015037)
0.0 0.1 GO:0046965 retinoid X receptor binding(GO:0046965)
0.0 0.1 GO:0015193 L-proline transmembrane transporter activity(GO:0015193)
0.0 0.1 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.0 0.1 GO:0050508 glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0050508)
0.0 0.1 GO:0031694 alpha-2A adrenergic receptor binding(GO:0031694)
0.0 0.2 GO:0005123 death receptor binding(GO:0005123)
0.0 0.0 GO:0004075 biotin carboxylase activity(GO:0004075)
0.0 0.0 GO:0016717 oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water(GO:0016717)
0.0 0.0 GO:0050253 retinyl-palmitate esterase activity(GO:0050253)
0.0 0.1 GO:0015280 ligand-gated sodium channel activity(GO:0015280)
0.0 1.8 GO:0016881 acid-amino acid ligase activity(GO:0016881)
0.0 0.0 GO:0033300 dehydroascorbic acid transporter activity(GO:0033300)
0.0 0.1 GO:0000309 nicotinamide-nucleotide adenylyltransferase activity(GO:0000309) nicotinate-nucleotide adenylyltransferase activity(GO:0004515)
0.0 0.0 GO:0004142 diacylglycerol cholinephosphotransferase activity(GO:0004142)
0.0 0.1 GO:0016679 ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors(GO:0016679) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.0 0.0 GO:0003960 NADPH:quinone reductase activity(GO:0003960)
0.0 0.3 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0 0.1 GO:0005534 galactose binding(GO:0005534)
0.0 0.2 GO:0008271 secondary active sulfate transmembrane transporter activity(GO:0008271)
0.0 0.1 GO:0008332 low voltage-gated calcium channel activity(GO:0008332)
0.0 0.1 GO:0030275 LRR domain binding(GO:0030275)
0.0 0.0 GO:0000104 succinate dehydrogenase activity(GO:0000104)
0.0 0.2 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.0 0.0 GO:0008113 peptide-methionine (S)-S-oxide reductase activity(GO:0008113)
0.0 0.1 GO:0050780 dopamine receptor binding(GO:0050780)
0.0 0.1 GO:0045502 dynein binding(GO:0045502)
0.0 0.1 GO:0003785 actin monomer binding(GO:0003785)
0.0 0.1 GO:0016647 oxidoreductase activity, acting on the CH-NH group of donors, oxygen as acceptor(GO:0016647)
0.0 0.1 GO:0030544 Hsp70 protein binding(GO:0030544)
0.0 0.1 GO:0031849 olfactory receptor binding(GO:0031849)
0.0 0.1 GO:0051183 vitamin transporter activity(GO:0051183)
0.0 0.1 GO:0030021 extracellular matrix structural constituent conferring compression resistance(GO:0030021) structural constituent of tooth enamel(GO:0030345)
0.0 0.1 GO:0004427 inorganic diphosphatase activity(GO:0004427)
0.0 0.1 GO:0030506 ankyrin binding(GO:0030506)
0.0 0.2 GO:0016500 protein-hormone receptor activity(GO:0016500)
0.0 0.1 GO:0005324 long-chain fatty acid transporter activity(GO:0005324)
0.0 0.1 GO:0043495 protein anchor(GO:0043495)
0.0 0.4 GO:0051539 4 iron, 4 sulfur cluster binding(GO:0051539)
0.0 0.2 GO:0005041 low-density lipoprotein receptor activity(GO:0005041)
0.0 0.0 GO:0070324 thyroid hormone binding(GO:0070324)
0.0 0.1 GO:0016941 natriuretic peptide receptor activity(GO:0016941)
0.0 0.0 GO:0070095 fructose-6-phosphate binding(GO:0070095)
0.0 0.2 GO:0008395 steroid hydroxylase activity(GO:0008395)
0.0 0.1 GO:0031544 procollagen-proline 3-dioxygenase activity(GO:0019797) peptidyl-proline 3-dioxygenase activity(GO:0031544)
0.0 0.1 GO:0005042 netrin receptor activity(GO:0005042)
0.0 0.0 GO:0043515 kinetochore binding(GO:0043515)
0.0 0.1 GO:0001609 G-protein coupled adenosine receptor activity(GO:0001609)
0.0 0.7 GO:0004714 transmembrane receptor protein tyrosine kinase activity(GO:0004714)
0.0 0.0 GO:0032407 MutSalpha complex binding(GO:0032407)
0.0 0.1 GO:0004668 protein-arginine deiminase activity(GO:0004668)
0.0 0.1 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.0 0.1 GO:0046920 alpha-(1->3)-fucosyltransferase activity(GO:0046920)
0.0 0.1 GO:0004985 opioid receptor activity(GO:0004985)
0.0 0.0 GO:0008401 retinoic acid 4-hydroxylase activity(GO:0008401)
0.0 0.2 GO:0050699 WW domain binding(GO:0050699)
0.0 0.3 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 0.2 GO:0048365 Rac GTPase binding(GO:0048365)
0.0 0.1 GO:0070815 peptidyl-lysine 5-dioxygenase activity(GO:0070815)
0.0 0.2 GO:0005109 frizzled binding(GO:0005109)
0.0 0.1 GO:0015321 sodium-dependent phosphate transmembrane transporter activity(GO:0015321)
0.0 0.3 GO:0008603 cAMP-dependent protein kinase regulator activity(GO:0008603)
0.0 0.2 GO:0004065 arylsulfatase activity(GO:0004065)
0.0 0.0 GO:0004030 aldehyde dehydrogenase [NAD(P)+] activity(GO:0004030)
0.0 0.1 GO:0001640 adenylate cyclase inhibiting G-protein coupled glutamate receptor activity(GO:0001640) G-protein coupled glutamate receptor activity(GO:0098988)
0.0 0.2 GO:0008536 Ran GTPase binding(GO:0008536)
0.0 0.1 GO:0004982 N-formyl peptide receptor activity(GO:0004982)
0.0 0.1 GO:0003756 protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864)
0.0 0.1 GO:0015245 fatty acid transporter activity(GO:0015245)
0.0 0.0 GO:0000247 C-8 sterol isomerase activity(GO:0000247)
0.0 0.1 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.0 0.0 GO:0008900 hydrogen:potassium-exchanging ATPase activity(GO:0008900)
0.0 0.2 GO:0005242 inward rectifier potassium channel activity(GO:0005242)
0.0 0.3 GO:0004190 aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001)
0.0 0.6 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)
0.0 0.4 GO:0001104 RNA polymerase II transcription cofactor activity(GO:0001104)
0.0 1.6 GO:0008083 growth factor activity(GO:0008083)
0.0 0.0 GO:0070548 L-glutamine aminotransferase activity(GO:0070548)
0.0 0.0 GO:0042808 obsolete neuronal Cdc2-like kinase binding(GO:0042808)
0.0 0.1 GO:0005375 copper ion transmembrane transporter activity(GO:0005375)
0.0 0.0 GO:0070644 vitamin D response element binding(GO:0070644)
0.0 0.1 GO:0051378 serotonin binding(GO:0051378)
0.0 0.1 GO:0017110 nucleoside-diphosphatase activity(GO:0017110)
0.0 1.4 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 0.0 GO:0043176 amine binding(GO:0043176)
0.0 0.1 GO:0004305 ethanolamine kinase activity(GO:0004305)
0.0 0.0 GO:0070576 vitamin D 24-hydroxylase activity(GO:0070576)
0.0 0.8 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 0.1 GO:0019841 retinol binding(GO:0019841)
0.0 0.2 GO:0005537 mannose binding(GO:0005537)
0.0 0.2 GO:0019825 oxygen binding(GO:0019825)
0.0 0.1 GO:0046790 virion binding(GO:0046790)
0.0 0.1 GO:0016423 tRNA (guanine) methyltransferase activity(GO:0016423)
0.0 0.1 GO:0017108 5'-flap endonuclease activity(GO:0017108)
0.0 0.1 GO:0019104 DNA N-glycosylase activity(GO:0019104)
0.0 0.7 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.0 0.0 GO:0003923 GPI-anchor transamidase activity(GO:0003923)
0.0 0.0 GO:0016934 extracellular-glycine-gated ion channel activity(GO:0016933) extracellular-glycine-gated chloride channel activity(GO:0016934)
0.0 0.0 GO:0015204 urea transmembrane transporter activity(GO:0015204)
0.0 0.0 GO:0050693 LBD domain binding(GO:0050693)
0.0 0.2 GO:0015036 disulfide oxidoreductase activity(GO:0015036)
0.0 0.1 GO:0001871 pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.0 0.3 GO:0004623 phospholipase A2 activity(GO:0004623)
0.0 0.0 GO:0034237 protein kinase A regulatory subunit binding(GO:0034237)
0.0 0.0 GO:0034584 piRNA binding(GO:0034584)
0.0 0.0 GO:0051400 BH domain binding(GO:0051400)
0.0 0.0 GO:0032450 maltose alpha-glucosidase activity(GO:0032450)
0.0 0.2 GO:0015125 bile acid transmembrane transporter activity(GO:0015125)
0.0 0.2 GO:0070330 aromatase activity(GO:0070330)
0.0 0.0 GO:0034190 apolipoprotein receptor binding(GO:0034190)
0.0 0.0 GO:0004616 phosphogluconate dehydrogenase (decarboxylating) activity(GO:0004616)
0.0 0.1 GO:0004385 guanylate kinase activity(GO:0004385)
0.0 0.1 GO:0017069 snRNA binding(GO:0017069)
0.0 0.1 GO:0004522 ribonuclease A activity(GO:0004522)
0.0 0.0 GO:0008266 poly(U) RNA binding(GO:0008266)
0.0 0.0 GO:0070696 transmembrane receptor protein serine/threonine kinase binding(GO:0070696)
0.0 0.0 GO:0005384 manganese ion transmembrane transporter activity(GO:0005384)
0.0 0.0 GO:0016886 ligase activity, forming phosphoric ester bonds(GO:0016886)
0.0 0.0 GO:0015562 efflux transmembrane transporter activity(GO:0015562)
0.0 0.1 GO:0004526 ribonuclease P activity(GO:0004526)
0.0 0.0 GO:0004523 RNA-DNA hybrid ribonuclease activity(GO:0004523)
0.0 0.2 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 0.2 GO:0004004 ATP-dependent RNA helicase activity(GO:0004004)
0.0 0.1 GO:0070567 cytidylyltransferase activity(GO:0070567)
0.0 0.1 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.0 0.0 GO:0031701 angiotensin receptor binding(GO:0031701)
0.0 0.1 GO:0051721 protein phosphatase 2A binding(GO:0051721)
0.0 0.0 GO:0005229 intracellular calcium activated chloride channel activity(GO:0005229)
0.0 0.1 GO:0004703 G-protein coupled receptor kinase activity(GO:0004703)
0.0 0.0 GO:0000403 Y-form DNA binding(GO:0000403)
0.0 0.1 GO:0015101 organic cation transmembrane transporter activity(GO:0015101)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.9 PID FAK PATHWAY Signaling events mediated by focal adhesion kinase
0.1 1.1 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.1 1.4 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.1 1.7 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.1 0.3 PID ANGIOPOIETIN RECEPTOR PATHWAY Angiopoietin receptor Tie2-mediated signaling
0.1 0.1 PID VEGFR1 PATHWAY VEGFR1 specific signals
0.1 0.2 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.1 0.1 SA FAS SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.1 3.5 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.1 0.3 ST INTEGRIN SIGNALING PATHWAY Integrin Signaling Pathway
0.1 0.4 PID AJDISS 2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.1 0.9 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.1 0.4 PID NETRIN PATHWAY Netrin-mediated signaling events
0.1 1.7 PID PI3KCI AKT PATHWAY Class I PI3K signaling events mediated by Akt
0.1 2.1 PID INTEGRIN3 PATHWAY Beta3 integrin cell surface interactions
0.1 0.1 PID GLYPICAN 1PATHWAY Glypican 1 network
0.0 0.2 PID EPHA2 FWD PATHWAY EPHA2 forward signaling
0.0 1.8 PID HNF3A PATHWAY FOXA1 transcription factor network
0.0 1.2 PID WNT SIGNALING PATHWAY Wnt signaling network
0.0 1.4 PID P38 ALPHA BETA DOWNSTREAM PATHWAY Signaling mediated by p38-alpha and p38-beta
0.0 0.0 SIG PIP3 SIGNALING IN B LYMPHOCYTES Genes related to PIP3 signaling in B lymphocytes
0.0 0.9 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.0 0.1 PID AR NONGENOMIC PATHWAY Nongenotropic Androgen signaling
0.0 1.4 PID ECADHERIN STABILIZATION PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.0 0.4 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.0 0.4 PID NECTIN PATHWAY Nectin adhesion pathway
0.0 0.6 PID ERBB2 ERBB3 PATHWAY ErbB2/ErbB3 signaling events
0.0 0.1 PID AMB2 NEUTROPHILS PATHWAY amb2 Integrin signaling
0.0 0.1 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.0 0.8 PID PS1 PATHWAY Presenilin action in Notch and Wnt signaling
0.0 0.3 PID ARF6 DOWNSTREAM PATHWAY Arf6 downstream pathway
0.0 0.4 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.0 0.3 PID ALK1 PATHWAY ALK1 signaling events
0.0 0.6 PID BMP PATHWAY BMP receptor signaling
0.0 0.4 PID S1P S1P2 PATHWAY S1P2 pathway
0.0 0.1 PID FOXO PATHWAY FoxO family signaling
0.0 0.1 PID IFNG PATHWAY IFN-gamma pathway
0.0 0.1 PID WNT CANONICAL PATHWAY Canonical Wnt signaling pathway
0.0 1.1 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.0 0.1 ST IL 13 PATHWAY Interleukin 13 (IL-13) Pathway
0.0 0.6 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.0 0.0 ST GRANULE CELL SURVIVAL PATHWAY Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway.
0.0 0.8 PID AVB3 INTEGRIN PATHWAY Integrins in angiogenesis
0.0 0.1 SA B CELL RECEPTOR COMPLEXES Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.0 0.7 PID REG GR PATHWAY Glucocorticoid receptor regulatory network
0.0 0.1 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.0 0.4 SIG PIP3 SIGNALING IN CARDIAC MYOCTES Genes related to PIP3 signaling in cardiac myocytes
0.0 0.0 ST INTERLEUKIN 4 PATHWAY Interleukin 4 (IL-4) Pathway
0.0 0.1 SA G1 AND S PHASES Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition.
0.0 0.1 PID NEPHRIN NEPH1 PATHWAY Nephrin/Neph1 signaling in the kidney podocyte
0.0 0.1 PID ECADHERIN NASCENT AJ PATHWAY E-cadherin signaling in the nascent adherens junction
0.0 0.7 PID TGFBR PATHWAY TGF-beta receptor signaling
0.0 0.6 PID RHOA REG PATHWAY Regulation of RhoA activity
0.0 0.7 PID AR PATHWAY Coregulation of Androgen receptor activity
0.0 0.1 PID SYNDECAN 4 PATHWAY Syndecan-4-mediated signaling events
0.0 0.4 PID IL1 PATHWAY IL1-mediated signaling events
0.0 0.1 PID THROMBIN PAR1 PATHWAY PAR1-mediated thrombin signaling events
0.0 2.9 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 0.1 PID HIF2PATHWAY HIF-2-alpha transcription factor network
0.0 0.1 PID HEDGEHOG GLI PATHWAY Hedgehog signaling events mediated by Gli proteins
0.0 0.0 SA TRKA RECEPTOR The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth.
0.0 0.4 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.0 0.2 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.0 0.2 PID FAS PATHWAY FAS (CD95) signaling pathway
0.0 0.2 PID RHODOPSIN PATHWAY Visual signal transduction: Rods
0.0 0.1 PID HIF1A PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.0 0.2 PID ARF 3PATHWAY Arf1 pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.3 REACTOME PI3K EVENTS IN ERBB2 SIGNALING Genes involved in PI3K events in ERBB2 signaling
0.2 1.6 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.1 0.1 REACTOME SHC1 EVENTS IN EGFR SIGNALING Genes involved in SHC1 events in EGFR signaling
0.1 0.1 REACTOME PLC BETA MEDIATED EVENTS Genes involved in PLC beta mediated events
0.1 2.2 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.1 1.9 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.1 1.0 REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.1 1.9 REACTOME PIP3 ACTIVATES AKT SIGNALING Genes involved in PIP3 activates AKT signaling
0.1 1.1 REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
0.1 0.9 REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING Genes involved in Advanced glycosylation endproduct receptor signaling
0.1 0.7 REACTOME PURINE CATABOLISM Genes involved in Purine catabolism
0.1 0.1 REACTOME REGULATION OF APOPTOSIS Genes involved in Regulation of Apoptosis
0.1 0.7 REACTOME SIGNALING BY NOTCH2 Genes involved in Signaling by NOTCH2
0.1 0.1 REACTOME PROSTACYCLIN SIGNALLING THROUGH PROSTACYCLIN RECEPTOR Genes involved in Prostacyclin signalling through prostacyclin receptor
0.1 0.6 REACTOME GAP JUNCTION DEGRADATION Genes involved in Gap junction degradation
0.1 1.5 REACTOME MYOGENESIS Genes involved in Myogenesis
0.1 0.1 REACTOME PROSTANOID LIGAND RECEPTORS Genes involved in Prostanoid ligand receptors
0.1 1.0 REACTOME HS GAG DEGRADATION Genes involved in HS-GAG degradation
0.1 0.9 REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE Genes involved in Synthesis of PIPs at the Golgi membrane
0.1 0.1 REACTOME APC CDC20 MEDIATED DEGRADATION OF NEK2A Genes involved in APC-Cdc20 mediated degradation of Nek2A
0.1 0.5 REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.0 1.3 REACTOME STEROID HORMONES Genes involved in Steroid hormones
0.0 0.4 REACTOME P75NTR RECRUITS SIGNALLING COMPLEXES Genes involved in p75NTR recruits signalling complexes
0.0 0.2 REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the late endosome membrane
0.0 0.2 REACTOME IL 3 5 AND GM CSF SIGNALING Genes involved in Interleukin-3, 5 and GM-CSF signaling
0.0 0.5 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.0 0.5 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.0 0.6 REACTOME DESTABILIZATION OF MRNA BY KSRP Genes involved in Destabilization of mRNA by KSRP
0.0 0.5 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
0.0 0.0 REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.0 0.5 REACTOME SIGNALING BY ACTIVATED POINT MUTANTS OF FGFR1 Genes involved in Signaling by activated point mutants of FGFR1
0.0 0.5 REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.0 0.6 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport
0.0 0.1 REACTOME REGULATION OF KIT SIGNALING Genes involved in Regulation of KIT signaling
0.0 0.2 REACTOME ADP SIGNALLING THROUGH P2RY12 Genes involved in ADP signalling through P2Y purinoceptor 12
0.0 0.3 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0 0.1 REACTOME TRANSPORT OF RIBONUCLEOPROTEINS INTO THE HOST NUCLEUS Genes involved in Transport of Ribonucleoproteins into the Host Nucleus
0.0 1.1 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 0.3 REACTOME ADP SIGNALLING THROUGH P2RY1 Genes involved in ADP signalling through P2Y purinoceptor 1
0.0 0.6 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0 0.5 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.0 0.1 REACTOME OPIOID SIGNALLING Genes involved in Opioid Signalling
0.0 0.5 REACTOME GRB2 EVENTS IN ERBB2 SIGNALING Genes involved in GRB2 events in ERBB2 signaling
0.0 0.8 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.0 0.3 REACTOME ACTIVATION OF GENES BY ATF4 Genes involved in Activation of Genes by ATF4
0.0 0.0 REACTOME AUTODEGRADATION OF THE E3 UBIQUITIN LIGASE COP1 Genes involved in Autodegradation of the E3 ubiquitin ligase COP1
0.0 0.2 REACTOME CELL CELL COMMUNICATION Genes involved in Cell-Cell communication
0.0 0.5 REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Glutamate Neurotransmitter Release Cycle
0.0 0.4 REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.0 0.4 REACTOME GRB2 SOS PROVIDES LINKAGE TO MAPK SIGNALING FOR INTERGRINS Genes involved in GRB2:SOS provides linkage to MAPK signaling for Intergrins
0.0 0.3 REACTOME MTORC1 MEDIATED SIGNALLING Genes involved in mTORC1-mediated signalling
0.0 0.0 REACTOME DESTABILIZATION OF MRNA BY AUF1 HNRNP D0 Genes involved in Destabilization of mRNA by AUF1 (hnRNP D0)
0.0 0.4 REACTOME PHOSPHORYLATION OF THE APC C Genes involved in Phosphorylation of the APC/C
0.0 0.6 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.0 0.1 REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.0 0.3 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.0 0.7 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor
0.0 0.3 REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.0 0.3 REACTOME PEPTIDE HORMONE BIOSYNTHESIS Genes involved in Peptide hormone biosynthesis
0.0 0.3 REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING Genes involved in Downregulation of TGF-beta receptor signaling
0.0 0.1 REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.0 0.3 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.0 0.4 REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.0 0.2 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.0 0.6 REACTOME KERATAN SULFATE KERATIN METABOLISM Genes involved in Keratan sulfate/keratin metabolism
0.0 0.0 REACTOME SOS MEDIATED SIGNALLING Genes involved in SOS-mediated signalling
0.0 0.2 REACTOME TIE2 SIGNALING Genes involved in Tie2 Signaling
0.0 0.3 REACTOME PROCESSIVE SYNTHESIS ON THE LAGGING STRAND Genes involved in Processive synthesis on the lagging strand
0.0 0.1 REACTOME CROSS PRESENTATION OF SOLUBLE EXOGENOUS ANTIGENS ENDOSOMES Genes involved in Cross-presentation of soluble exogenous antigens (endosomes)
0.0 0.0 REACTOME PERK REGULATED GENE EXPRESSION Genes involved in PERK regulated gene expression
0.0 0.4 REACTOME RNA POL III TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase III Transcription Termination
0.0 0.1 REACTOME G2 M DNA DAMAGE CHECKPOINT Genes involved in G2/M DNA damage checkpoint
0.0 0.6 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.0 0.4 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.0 1.1 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.0 0.3 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines
0.0 0.1 REACTOME INFLUENZA VIRAL RNA TRANSCRIPTION AND REPLICATION Genes involved in Influenza Viral RNA Transcription and Replication
0.0 0.3 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.0 0.5 REACTOME GLUCONEOGENESIS Genes involved in Gluconeogenesis
0.0 0.1 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts
0.0 0.4 REACTOME AMINE COMPOUND SLC TRANSPORTERS Genes involved in Amine compound SLC transporters
0.0 0.2 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.0 0.7 REACTOME L1CAM INTERACTIONS Genes involved in L1CAM interactions
0.0 0.1 REACTOME PD1 SIGNALING Genes involved in PD-1 signaling
0.0 0.1 REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK Genes involved in Regulation of Rheb GTPase activity by AMPK
0.0 0.2 REACTOME SEROTONIN RECEPTORS Genes involved in Serotonin receptors
0.0 0.2 REACTOME PEROXISOMAL LIPID METABOLISM Genes involved in Peroxisomal lipid metabolism
0.0 0.1 REACTOME ABACAVIR TRANSPORT AND METABOLISM Genes involved in Abacavir transport and metabolism
0.0 0.1 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.0 0.1 REACTOME DESTABILIZATION OF MRNA BY TRISTETRAPROLIN TTP Genes involved in Destabilization of mRNA by Tristetraprolin (TTP)
0.0 0.2 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.0 0.6 REACTOME GLUCOSE TRANSPORT Genes involved in Glucose transport
0.0 0.1 REACTOME HORMONE LIGAND BINDING RECEPTORS Genes involved in Hormone ligand-binding receptors
0.0 0.0 REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.0 0.2 REACTOME MEIOTIC RECOMBINATION Genes involved in Meiotic Recombination
0.0 0.1 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS Genes involved in Synthesis of bile acids and bile salts
0.0 0.2 REACTOME FRS2 MEDIATED CASCADE Genes involved in FRS2-mediated cascade
0.0 0.2 REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT Genes involved in Organic cation/anion/zwitterion transport
0.0 0.1 REACTOME SIGNAL ATTENUATION Genes involved in Signal attenuation
0.0 0.7 REACTOME ACTIVATION OF THE MRNA UPON BINDING OF THE CAP BINDING COMPLEX AND EIFS AND SUBSEQUENT BINDING TO 43S Genes involved in Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S
0.0 0.2 REACTOME FORMATION OF INCISION COMPLEX IN GG NER Genes involved in Formation of incision complex in GG-NER
0.0 0.3 REACTOME ACYL CHAIN REMODELLING OF PC Genes involved in Acyl chain remodelling of PC
0.0 0.1 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.0 0.2 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
0.0 0.2 REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS Genes involved in Tandem pore domain potassium channels
0.0 0.0 REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.0 0.0 REACTOME P130CAS LINKAGE TO MAPK SIGNALING FOR INTEGRINS Genes involved in p130Cas linkage to MAPK signaling for integrins
0.0 0.5 REACTOME INTEGRIN CELL SURFACE INTERACTIONS Genes involved in Integrin cell surface interactions
0.0 0.0 REACTOME ACETYLCHOLINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Acetylcholine Neurotransmitter Release Cycle
0.0 0.0 REACTOME NEP NS2 INTERACTS WITH THE CELLULAR EXPORT MACHINERY Genes involved in NEP/NS2 Interacts with the Cellular Export Machinery
0.0 0.0 REACTOME ALPHA LINOLENIC ACID ALA METABOLISM Genes involved in alpha-linolenic acid (ALA) metabolism
0.0 0.6 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins
0.0 0.1 REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.0 0.1 REACTOME PRE NOTCH TRANSCRIPTION AND TRANSLATION Genes involved in Pre-NOTCH Transcription and Translation
0.0 0.1 REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 2 PROMOTER Genes involved in RNA Polymerase III Transcription Initiation From Type 2 Promoter
0.0 0.1 REACTOME ROLE OF DCC IN REGULATING APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.0 0.2 REACTOME PLATELET CALCIUM HOMEOSTASIS Genes involved in Platelet calcium homeostasis
0.0 0.4 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 0.3 REACTOME FORMATION OF FIBRIN CLOT CLOTTING CASCADE Genes involved in Formation of Fibrin Clot (Clotting Cascade)
0.0 0.1 REACTOME A TETRASACCHARIDE LINKER SEQUENCE IS REQUIRED FOR GAG SYNTHESIS Genes involved in A tetrasaccharide linker sequence is required for GAG synthesis
0.0 0.2 REACTOME EXTRACELLULAR MATRIX ORGANIZATION Genes involved in Extracellular matrix organization