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ENCODE: H3K4me1 ChIP-Seq of primary human cells

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Results for RAD21_SMC3

Z-value: 2.88

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Transcription factors associated with RAD21_SMC3

Gene Symbol	Gene ID	Gene Info
RAD21 Ensembl NCBI GeneCards UniProt	ENSG00000164754.8	RAD21 cohesin complex component
SMC3 Ensembl NCBI GeneCards UniProt	ENSG00000108055.9	structural maintenance of chromosomes 3

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE	Gene	Distance	Association probability	Pearson corr. coef.	P-value	Plot
chr8_117862192_117862343	RAD21	545	0.758154	-0.63	6.9e-02	Click!
chr8_117861772_117861984	RAD21	156	0.952859	-0.58	9.8e-02	Click!
chr8_117877264_117877482	RAD21	9226	0.163313	0.57	1.1e-01	Click!
chr8_117887499_117887668	RAD21	478	0.434877	0.53	1.5e-01	Click!
chr8_117862032_117862183	RAD21	385	0.850524	-0.50	1.7e-01	Click!
chr10_112293168_112293319	SMC3	34206	0.125425	-0.76	1.8e-02	Click!
chr10_112292973_112293124	SMC3	34401	0.125004	-0.71	3.2e-02	Click!
chr10_112296172_112296422	SMC3	31152	0.131982	-0.59	9.6e-02	Click!
chr10_112296467_112296618	SMC3	30907	0.132503	-0.58	1.0e-01	Click!
chr10_112294383_112294534	SMC3	32991	0.128046	-0.57	1.1e-01	Click!

Activity of the RAD21_SMC3 motif across conditions

Conditions sorted by the z-value of the RAD21_SMC3 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE)	Target Score	Top associated gene	Gene Info	Distance of CRE to TSS	CRE/Gene association probability
chr2_219033507_219033793	1.31	CXCR1	chemokine (C-X-C motif) receptor 1	1932	0.25
chr3_51709792_51710106	1.24	TEX264	testis expressed 264	4038	0.18
chr9_95731156_95731601	1.21	FGD3	FYVE, RhoGEF and PH domain containing 3	5135	0.24
chr20_5549871_5550022	1.18	GPCPD1	glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae)	6208	0.26
chrX_73770256_73770407	1.15	SLC16A2	solute carrier family 16, member 2 (thyroid hormone transporter)	29376	0.19
chr19_41847706_41847892	1.07	TGFB1	transforming growth factor, beta 1	136	0.92
chr14_88480135_88480311	1.03	RP11-300J18.2		1732	0.33
chr1_182054151_182054410	0.98	ZNF648	zinc finger protein 648	23433	0.27
chrX_68505919_68506070	0.98	PJA1	praja ring finger 1, E3 ubiquitin protein ligase	120358	0.06
chr15_22462348_22462499	0.97	IGHV1OR15-3	immunoglobulin heavy variable 1/OR15-3 (pseudogene)	4070	0.14
chr11_68730135_68730286	0.97	MRGPRD	MAS-related GPR, member D	18245	0.12
chr17_471285_471436	0.97	RP5-1029F21.2		15554	0.18
chr10_43844065_43844216	0.94	ENSG00000221468	.	6906	0.19
chr20_30090993_30091144	0.93	HM13	histocompatibility (minor) 13	11163	0.12
chr2_43397687_43397838	0.93	ZFP36L2	ZFP36 ring finger protein-like 2	55986	0.13
chr14_22328339_22328490	0.92	ENSG00000222776	.	79629	0.1
chr4_120971093_120971244	0.92	RP11-679C8.2		16945	0.21
chr22_24836794_24837005	0.91	ADORA2A	adenosine A2a receptor	8091	0.18
chr6_41159448_41159599	0.90	TREML2	triggering receptor expressed on myeloid cells-like 2	9409	0.13
chr3_48586231_48586382	0.89	PFKFB4	6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4	7950	0.1
chr11_2320673_2321045	0.88	C11orf21	chromosome 11 open reading frame 21	2284	0.19
chrX_123345247_123345413	0.85	ENSG00000252693	.	13737	0.27
chr10_4857655_4857812	0.85	AKR1E2	aldo-keto reductase family 1, member E2	10713	0.26
chr5_139348441_139348592	0.85	ENSG00000207317	.	50561	0.12
chr15_91814858_91815009	0.84	SV2B	synaptic vesicle glycoprotein 2B	45833	0.18
chr1_192988705_192988856	0.84	UCHL5	ubiquitin carboxyl-terminal hydrolase L5	4272	0.22
chr6_36461129_36461297	0.84	ENSG00000264878	.	17162	0.13
chrX_78142186_78142337	0.83	P2RY10	purinergic receptor P2Y, G-protein coupled, 10	58568	0.16
chr1_65528662_65528934	0.83	ENSG00000199135	.	4607	0.21
chr17_76133393_76133675	0.82	TMC6	transmembrane channel-like 6	5046	0.12
chr19_46521204_46521355	0.82	ENSG00000211580	.	911	0.45
chrX_78206013_78206346	0.81	P2RY10	purinergic receptor P2Y, G-protein coupled, 10	5261	0.35
chr4_126234674_126234825	0.81	FAT4	FAT atypical cadherin 4	2805	0.38
chrX_12919691_12919842	0.80	TLR8	toll-like receptor 8	4973	0.21
chr14_81930928_81931079	0.80	STON2	stonin 2	28194	0.24
chr7_99949544_99949873	0.79	PILRB	paired immunoglobin-like type 2 receptor beta	91	0.72
chr16_88764542_88764951	0.79	RNF166	ring finger protein 166	1368	0.18
chr12_50190891_50191042	0.79	NCKAP5L	NCK-associated protein 5-like	181	0.94
chr22_36844473_36844624	0.78	ENSG00000252225	.	7533	0.15
chr5_66452974_66453257	0.77	MAST4	microtubule associated serine/threonine kinase family member 4	14853	0.25
chr12_57977152_57977303	0.77	PIP4K2C	phosphatidylinositol-5-phosphate 4-kinase, type II, gamma	7730	0.08
chr10_119256113_119256389	0.77	EMX2OS	EMX2 opposite strand/antisense RNA	2052	0.4
chr14_98073650_98073890	0.77	ENSG00000240730	.	77260	0.12
chr8_37413073_37413627	0.76	RP11-150O12.6		38811	0.17
chr15_89199438_89199630	0.75	ISG20	interferon stimulated exonuclease gene 20kDa	17350	0.16
chr11_61665278_61665429	0.75	RAB3IL1	RAB3A interacting protein (rabin3)-like 1	1457	0.29
chr9_99704616_99704767	0.75	NUTM2G	NUT family member 2G	13405	0.23
chr12_52414675_52414826	0.75	NR4A1	nuclear receptor subfamily 4, group A, member 1	1866	0.24
chr8_15235853_15236004	0.75	SGCZ	sarcoglycan, zeta	140080	0.05
chr1_62054460_62054611	0.74	ENSG00000264551	.	40168	0.2
chr17_32992455_32992677	0.74	TMEM132E	transmembrane protein 132E	84798	0.09
chr17_55675279_55675493	0.74	RP11-118E18.4		10387	0.2
chr14_90755753_90755904	0.74	NRDE2	NRDE-2, necessary for RNA interference, domain containing	13353	0.21
chrX_128889671_128889975	0.74	XPNPEP2	X-prolyl aminopeptidase (aminopeptidase P) 2, membrane-bound	16825	0.18
chr10_32236618_32236769	0.74	ARHGAP12	Rho GTPase activating protein 12	18951	0.22
chr3_52254502_52254766	0.74	TLR9	toll-like receptor 9	5545	0.11
chr22_35546679_35546830	0.73	RP1-272J12.1		78495	0.09
chr5_177236219_177236370	0.73	FAM153A	family with sequence similarity 153, member A	25895	0.14
chr8_38578951_38579216	0.73	TACC1	transforming, acidic coiled-coil containing protein 1	6621	0.22
chr10_28682947_28683098	0.72	ENSG00000222666	.	14158	0.21
chr9_94537879_94538030	0.72	ENSG00000266855	.	139421	0.05
chr13_41927332_41927587	0.72	ENSG00000223280	.	1336	0.45
chr19_13094464_13094615	0.72	NFIX	nuclear factor I/X (CCAAT-binding transcription factor)	11883	0.07
chr19_45303755_45303938	0.72	BCAM	basal cell adhesion molecule (Lutheran blood group)	8482	0.12
chr22_37635708_37636125	0.72	RAC2	ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2)	4372	0.17
chr19_9958893_9959044	0.72	ENSG00000266247	.	3136	0.12
chr14_103160895_103161103	0.71	ENSG00000202459	.	726	0.72
chr20_35548263_35548529	0.71	SAMHD1	SAM domain and HD domain 1	31715	0.14
chr19_1035998_1036167	0.71	AC011558.5		2981	0.1
chr22_24822979_24823130	0.71	ADORA2A	adenosine A2a receptor	476	0.81
chr4_3882373_3882524	0.71	AC226119.4		43553	0.17
chr20_13768978_13769129	0.70	NDUFAF5	NADH dehydrogenase (ubiquinone) complex I, assembly factor 5	3357	0.27
chr1_207085195_207085346	0.70	FAIM3	Fas apoptotic inhibitory molecule 3	9942	0.14
chr3_196336211_196336362	0.70	LINC01063	long intergenic non-protein coding RNA 1063	23172	0.11
chr1_26864411_26864784	0.69	RPS6KA1	ribosomal protein S6 kinase, 90kDa, polypeptide 1	5006	0.16
chr6_81048075_81048226	0.69	BCKDHB	branched chain keto acid dehydrogenase E1, beta polypeptide	231767	0.02
chr19_50060873_50061024	0.69	NOSIP	nitric oxide synthase interacting protein	2939	0.1
chr10_112653462_112653613	0.68	ENSG00000265827	.	4311	0.15
chr15_22511132_22511399	0.68	ENSG00000221641	.	2015	0.27
chr7_72385645_72385796	0.68	POM121	POM121 transmembrane nucleoporin	9940	0.12
chr19_16358576_16358749	0.68	AP1M1	adaptor-related protein complex 1, mu 1 subunit	20246	0.14
chr3_37254643_37254794	0.68	ENSG00000238929	.	16486	0.14
chr3_138830722_138830873	0.68	MRPS22	mitochondrial ribosomal protein S22	1551	0.47
chr14_24559849_24560138	0.68	PCK2	phosphoenolpyruvate carboxykinase 2 (mitochondrial)	3269	0.1
chr3_181966234_181966385	0.68	ENSG00000252257	.	280062	0.01
chr5_164885022_164885173	0.67	ENSG00000252794	.	151349	0.05
chr20_33862742_33863095	0.67	MMP24-AS1	MMP24 antisense RNA 1	2912	0.13
chr20_31490432_31490747	0.66	EFCAB8	EF-hand calcium binding domain 8	8870	0.2
chr19_51425673_51425824	0.66	KLK4	kallikrein-related peptidase 4	11754	0.08
chr16_68738331_68738482	0.66	CDH3	cadherin 3, type 1, P-cadherin (placental)	8678	0.15
chr15_90686478_90686715	0.66	ENSG00000263714	.	12947	0.12
chr10_4858075_4858226	0.66	AKR1E2	aldo-keto reductase family 1, member E2	10296	0.26
chr8_25946315_25946466	0.66	EBF2	early B-cell factor 2	43477	0.17
chr3_42578042_42578193	0.66	VIPR1-AS1	VIPR1 antisense RNA 1	3367	0.19
chr9_97077448_97077599	0.65	NUTM2F	NUT family member 2F	13403	0.18
chr8_96260916_96261159	0.65	C8orf37	chromosome 8 open reading frame 37	20392	0.24
chr20_54975146_54975297	0.65	CSTF1	cleavage stimulation factor, 3' pre-RNA, subunit 1, 50kDa	7514	0.14
chr6_36997175_36997385	0.65	COX6A1P2	cytochrome c oxidase subunit VIa polypeptide 1 pseudogene 2	15327	0.17
chr10_28658229_28658562	0.65	MPP7	membrane protein, palmitoylated 7 (MAGUK p55 subfamily member 7)	34980	0.15
chr11_119561542_119562348	0.65	ENSG00000199217	.	34924	0.14
chr17_74270345_74270531	0.64	QRICH2	glutamine rich 2	6000	0.13
chr8_55078889_55079040	0.64	ENSG00000251835	.	13522	0.21
chr6_109791197_109791348	0.64	MICAL1	microtubule associated monooxygenase, calponin and LIM domain containing 1	4101	0.13
chr3_155577775_155577926	0.64	SLC33A1	solute carrier family 33 (acetyl-CoA transporter), member 1	5632	0.22
chr9_95890203_95890354	0.64	NINJ1	ninjurin 1	6292	0.18
chr10_85974471_85974622	0.63	LRIT2	leucine-rich repeat, immunoglobulin-like and transmembrane domains 2	10736	0.14
chr3_172077152_172077303	0.63	AC092964.1	Uncharacterized protein	43009	0.15
chr10_64441374_64441558	0.63	ENSG00000263920	.	23521	0.21
chr19_42439130_42439281	0.63	ARHGEF1	Rho guanine nucleotide exchange factor (GEF) 1	11959	0.12
chr2_1554615_1554766	0.63	TPO	thyroid peroxidase	47141	0.17
chr10_73506481_73506632	0.63	C10orf105	chromosome 10 open reading frame 105	8975	0.2
chr12_54793232_54793383	0.62	ITGA5	integrin, alpha 5 (fibronectin receptor, alpha polypeptide)	390	0.75
chr19_21492009_21492160	0.62	ZNF708	zinc finger protein 708	20054	0.21
chr14_105525570_105525755	0.62	GPR132	G protein-coupled receptor 132	1843	0.34
chr17_46962186_46962337	0.62	ENSG00000212565	.	4059	0.13
chr1_32421709_32421860	0.62	PTP4A2	protein tyrosine phosphatase type IVA, member 2	13607	0.17
chr2_233924263_233924811	0.62	INPP5D	inositol polyphosphate-5-phosphatase, 145kDa	140	0.96
chr20_62701141_62701292	0.61	TCEA2	transcription elongation factor A (SII), 2	3652	0.11
chr14_53773006_53773157	0.61	RP11-547D23.1		153009	0.04
chr16_68624461_68624612	0.61	RP11-615I2.1		1121	0.41
chr6_166814464_166814615	0.60	RP1-168L15.5		17862	0.16
chr7_38262255_38262771	0.60	STARD3NL	STARD3 N-terminal like	44516	0.2
chr9_134466441_134466779	0.60	RAPGEF1	Rap guanine nucleotide exchange factor (GEF) 1	30615	0.15
chr19_40256275_40256426	0.60	LEUTX	leucine twenty homeobox	10885	0.14
chr14_68026411_68026562	0.60	PLEKHH1	pleckstrin homology domain containing, family H (with MyTH4 domain) member 1	18794	0.13
chr1_150436979_150437219	0.60	TARS2	threonyl-tRNA synthetase 2, mitochondrial (putative)	22788	0.12
chr7_142153280_142153613	0.60	PRSS3P3	protease, serine, 3 pseudogene 3	163837	0.03
chr9_100652159_100652434	0.60	C9orf156	chromosome 9 open reading frame 156	22457	0.14
chr14_102650737_102650931	0.60	WDR20	WD repeat domain 20	10449	0.19
chr12_56390067_56390218	0.59	SUOX	sulfite oxidase	822	0.39
chr10_517089_517240	0.59	RP11-490E15.2		33663	0.17
chr3_141022380_141022531	0.59	ZBTB38	zinc finger and BTB domain containing 38	20600	0.2
chr7_39559652_39559803	0.59	AC011290.4		46111	0.14
chr13_41351757_41352104	0.59	MRPS31	mitochondrial ribosomal protein S31	6621	0.18
chr17_65383117_65383336	0.59	PITPNC1	phosphatidylinositol transfer protein, cytoplasmic 1	8144	0.14
chr11_68065271_68065422	0.59	LRP5	low density lipoprotein receptor-related protein 5	14731	0.19
chr14_22320430_22320581	0.59	ENSG00000222776	.	71720	0.11
chr11_271383_271534	0.59	NLRP6	NLR family, pyrin domain containing 6	6907	0.08
chr19_44270748_44270899	0.58	KCNN4	potassium intermediate/small conductance calcium-activated channel, subfamily N, member 4	2306	0.2
chr22_23096107_23096258	0.58	IGLV3-15	immunoglobulin lambda variable 3-15 (pseudogene)	1861	0.09
chr3_52481099_52481277	0.58	SEMA3G	sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3G	2087	0.18
chr5_132446977_132447128	0.58	CTB-49A3.2		49078	0.12
chr19_7918237_7918388	0.58	EVI5L	ecotropic viral integration site 5-like	3405	0.12
chr16_629127_629313	0.58	PIGQ	phosphatidylinositol glycan anchor biosynthesis, class Q	129	0.89
chr3_51703216_51703504	0.58	TEX264	testis expressed 264	1862	0.29
chr8_21763538_21763697	0.58	DOK2	docking protein 2, 56kDa	7557	0.2
chr22_38749183_38749334	0.58	RP3-449O17.1		30843	0.11
chr2_85091739_85091919	0.58	TRABD2A	TraB domain containing 2A	16377	0.19
chr8_10450393_10450544	0.57	PRSS51	protease, serine, 51	45373	0.11
chr15_71407620_71407771	0.57	CT62	cancer/testis antigen 62	111	0.97
chr16_11665341_11665682	0.57	LITAF	lipopolysaccharide-induced TNF factor	14718	0.18
chr1_161179737_161179888	0.57	FCER1G	Fc fragment of IgE, high affinity I, receptor for; gamma polypeptide	5257	0.07
chr2_137180913_137181244	0.57	ENSG00000251976	.	33176	0.23
chr11_128354141_128354347	0.57	ETS1	v-ets avian erythroblastosis virus E26 oncogene homolog 1	21045	0.23
chr9_112945663_112945814	0.57	C9orf152	chromosome 9 open reading frame 152	24731	0.21
chr1_185528909_185529229	0.57	ENSG00000207108	.	70591	0.11
chr5_141339545_141339774	0.56	PCDH12	protocadherin 12	1032	0.38
chr14_107287584_107287735	0.56	IGHVIII-82	immunoglobulin heavy variable (III)-82 (pseudogene)	360	0.68
chr1_236267080_236267342	0.56	GPR137B	G protein-coupled receptor 137B	38621	0.14
chr19_4809653_4809804	0.56	AC005523.2		14157	0.1
chr5_9361958_9362109	0.56	CTD-2201E9.4		1354	0.52
chr6_36727105_36727256	0.56	CPNE5	copine V	1994	0.33
chr11_15238304_15238455	0.56	INSC	inscuteable homolog (Drosophila)	67725	0.14
chr22_37635436_37635704	0.56	RAC2	ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2)	4718	0.16
chr16_50699390_50699541	0.55	RP11-401P9.5		657	0.62
chr10_483191_483342	0.55	RP11-490E15.2		235	0.93
chr17_42997475_42997626	0.55	GFAP	glial fibrillary acidic protein	3245	0.13
chr3_31592350_31592501	0.55	STT3B	STT3B, subunit of the oligosaccharyltransferase complex (catalytic)	18143	0.28
chr14_64236964_64237115	0.55	ENSG00000252749	.	33877	0.15
chrX_153089650_153089801	0.55	PDZD4	PDZ domain containing 4	5626	0.1
chr1_211526157_211526486	0.55	TRAF5	TNF receptor-associated factor 5	6615	0.27
chr10_45504201_45504352	0.54	C10orf25	chromosome 10 open reading frame 25	7940	0.14
chr1_155149147_155149298	0.54	TRIM46	tripartite motif containing 46	2779	0.08
chr13_24827210_24827496	0.54	SPATA13-AS1	SPATA13 antisense RNA 1	1224	0.37
chr14_55556326_55556477	0.54	LGALS3	lectin, galactoside-binding, soluble, 3	34427	0.15
chr11_1876820_1877006	0.54	LSP1	lymphocyte-specific protein 1	2713	0.14
chr17_62384310_62384461	0.54	TEX2	testis expressed 2	43724	0.13
chr7_128021290_128021441	0.54	PRRT4	proline-rich transmembrane protein 4	19626	0.12
chr6_160955325_160955476	0.54	LPAL2	lipoprotein, Lp(a)-like 2, pseudogene	23361	0.25
chr3_178154623_178154774	0.54	ENSG00000252336	.	7620	0.25
chr3_186757562_186757727	0.54	ST6GAL1	ST6 beta-galactosamide alpha-2,6-sialyltranferase 1	3887	0.29
chr22_23583322_23583546	0.54	BCR	breakpoint cluster region	12713	0.16
chr1_168391373_168391682	0.54	ENSG00000207974	.	46765	0.16
chr4_154564728_154564879	0.54	RP11-153M7.3		34608	0.16
chr15_56788888_56789039	0.54	MNS1	meiosis-specific nuclear structural 1	31628	0.22
chr10_82296121_82296521	0.54	RP11-137H2.4		623	0.66
chr3_53730913_53731064	0.53	CACNA1D	calcium channel, voltage-dependent, L type, alpha 1D subunit	30560	0.19
chr16_87814053_87814528	0.53	KLHDC4	kelch domain containing 4	14708	0.17
chr3_11102557_11102708	0.53	SLC6A1-AS1	SLC6A1 antisense RNA 1	41722	0.16
chr11_124706901_124707078	0.53	ENSG00000215942	.	6054	0.12
chr12_122226099_122226875	0.53	RHOF	ras homolog family member F (in filopodia)	4779	0.18
chr21_30165513_30165664	0.53	ENSG00000251894	.	50058	0.16
chr16_88810116_88810391	0.53	RP5-1142A6.8		1024	0.28
chrX_152201123_152201274	0.53	PNMA3	paraneoplastic Ma antigen 3	23568	0.12
chr1_93324618_93324769	0.53	ENSG00000207022	.	13077	0.12
chr16_85004202_85004353	0.53	ZDHHC7	zinc finger, DHHC-type containing 7	11446	0.23
chr3_57023054_57023235	0.53	ARHGEF3	Rho guanine nucleotide exchange factor (GEF) 3	11741	0.22
chr9_88040207_88040358	0.53	AGTPBP1	ATP/GTP binding protein 1	255919	0.02
chr14_105994810_105994961	0.52	TMEM121	transmembrane protein 121	76	0.96
chr3_30810280_30810431	0.52	RP11-1024P17.1		71202	0.13

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of RAD21_SMC3

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.4	1.1	GO:0052251	induction by organism of defense response of other organism involved in symbiotic interaction(GO:0052251)
0.3	0.8	GO:0014056	acetylcholine secretion, neurotransmission(GO:0014055) regulation of acetylcholine secretion, neurotransmission(GO:0014056) acetylcholine secretion(GO:0061526)
0.2	0.7	GO:0030223	neutrophil differentiation(GO:0030223)
0.1	0.6	GO:0007171	activation of transmembrane receptor protein tyrosine kinase activity(GO:0007171)
0.1	0.3	GO:0010766	negative regulation of sodium ion transport(GO:0010766)
0.1	0.3	GO:0072162	mesenchymal cell differentiation involved in kidney development(GO:0072161) metanephric mesenchymal cell differentiation(GO:0072162) mesenchymal cell differentiation involved in renal system development(GO:2001012)
0.1	0.3	GO:0042271	susceptibility to natural killer cell mediated cytotoxicity(GO:0042271)
0.1	0.4	GO:0045356	positive regulation of interferon-alpha biosynthetic process(GO:0045356)
0.1	0.3	GO:0031536	positive regulation of exit from mitosis(GO:0031536)
0.1	0.4	GO:0032237	activation of store-operated calcium channel activity(GO:0032237) regulation of store-operated calcium channel activity(GO:1901339) positive regulation of store-operated calcium channel activity(GO:1901341)
0.1	0.3	GO:0045048	protein insertion into ER membrane(GO:0045048) tail-anchored membrane protein insertion into ER membrane(GO:0071816)
0.1	0.2	GO:0043117	positive regulation of vascular permeability(GO:0043117)
0.1	0.2	GO:0001821	histamine secretion(GO:0001821)
0.1	0.6	GO:0051927	obsolete negative regulation of calcium ion transport via voltage-gated calcium channel activity(GO:0051927)
0.1	0.3	GO:0051497	negative regulation of stress fiber assembly(GO:0051497)
0.1	0.2	GO:0010980	regulation of vitamin D 24-hydroxylase activity(GO:0010979) positive regulation of vitamin D 24-hydroxylase activity(GO:0010980)
0.1	0.1	GO:0060340	positive regulation of type I interferon-mediated signaling pathway(GO:0060340)
0.1	0.2	GO:1903504	positive regulation of spindle checkpoint(GO:0090232) regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090266) positive regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090267) positive regulation of cell cycle checkpoint(GO:1901978) regulation of mitotic spindle checkpoint(GO:1903504)
0.1	0.2	GO:0021542	dentate gyrus development(GO:0021542)
0.1	0.3	GO:0048172	regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.1	0.5	GO:0035313	wound healing, spreading of epidermal cells(GO:0035313) wound healing, spreading of cells(GO:0044319) epiboly(GO:0090504) epiboly involved in wound healing(GO:0090505)
0.1	0.3	GO:0002726	positive regulation of T cell cytokine production(GO:0002726)
0.1	0.2	GO:0002072	optic cup morphogenesis involved in camera-type eye development(GO:0002072)
0.1	0.7	GO:0042273	ribosomal large subunit biogenesis(GO:0042273)
0.1	0.5	GO:0006553	lysine metabolic process(GO:0006553) lysine catabolic process(GO:0006554)
0.1	0.2	GO:0010447	response to acidic pH(GO:0010447)
0.1	0.4	GO:0006516	glycoprotein catabolic process(GO:0006516)
0.1	0.1	GO:0030970	retrograde protein transport, ER to cytosol(GO:0030970)
0.1	0.1	GO:0046137	negative regulation of calcidiol 1-monooxygenase activity(GO:0010956) negative regulation of vitamin D biosynthetic process(GO:0010957) negative regulation of vitamin metabolic process(GO:0046137)
0.1	0.4	GO:0032494	response to peptidoglycan(GO:0032494)
0.1	0.2	GO:2000300	regulation of synaptic vesicle transport(GO:1902803) regulation of synaptic vesicle exocytosis(GO:2000300)
0.1	0.2	GO:0006189	'de novo' IMP biosynthetic process(GO:0006189)
0.1	0.2	GO:0051182	coenzyme transport(GO:0051182)
0.0	0.2	GO:0007008	outer mitochondrial membrane organization(GO:0007008) protein import into mitochondrial outer membrane(GO:0045040)
0.0	0.3	GO:0033005	positive regulation of mast cell activation(GO:0033005)
0.0	0.2	GO:0042989	sequestering of actin monomers(GO:0042989)
0.0	0.1	GO:0061299	retina vasculature development in camera-type eye(GO:0061298) retina vasculature morphogenesis in camera-type eye(GO:0061299)
0.0	0.5	GO:0034446	substrate adhesion-dependent cell spreading(GO:0034446)
0.0	0.1	GO:0007221	positive regulation of transcription of Notch receptor target(GO:0007221)
0.0	0.1	GO:0072131	kidney mesenchyme morphogenesis(GO:0072131) metanephric mesenchyme morphogenesis(GO:0072133)
0.0	0.1	GO:0060398	regulation of growth hormone receptor signaling pathway(GO:0060398)
0.0	0.2	GO:0032486	Rap protein signal transduction(GO:0032486)
0.0	0.2	GO:0021631	optic nerve morphogenesis(GO:0021631)
0.0	0.2	GO:0060605	tube lumen cavitation(GO:0060605) salivary gland cavitation(GO:0060662)
0.0	0.1	GO:0090231	regulation of spindle checkpoint(GO:0090231)
0.0	0.1	GO:0042536	negative regulation of tumor necrosis factor biosynthetic process(GO:0042536)
0.0	0.6	GO:0016254	preassembly of GPI anchor in ER membrane(GO:0016254)
0.0	0.1	GO:0060242	contact inhibition(GO:0060242)
0.0	0.1	GO:0006384	transcription initiation from RNA polymerase III promoter(GO:0006384)
0.0	0.2	GO:0043045	DNA methylation involved in embryo development(GO:0043045) changes to DNA methylation involved in embryo development(GO:1901538)
0.0	0.1	GO:0009048	dosage compensation by inactivation of X chromosome(GO:0009048)
0.0	0.5	GO:0045576	mast cell activation(GO:0045576)
0.0	0.0	GO:0090075	relaxation of muscle(GO:0090075)
0.0	0.5	GO:0001782	B cell homeostasis(GO:0001782)
0.0	0.1	GO:0035405	histone-threonine phosphorylation(GO:0035405)
0.0	0.2	GO:0043951	negative regulation of cAMP-mediated signaling(GO:0043951)
0.0	0.1	GO:1902305	regulation of sodium:proton antiporter activity(GO:0032415) regulation of sodium ion transmembrane transport(GO:1902305) regulation of sodium ion transmembrane transporter activity(GO:2000649)
0.0	0.1	GO:0061154	endothelial tube morphogenesis(GO:0061154)
0.0	0.2	GO:0060251	regulation of glial cell proliferation(GO:0060251)
0.0	0.0	GO:0002513	tolerance induction to self antigen(GO:0002513)
0.0	0.1	GO:0043457	regulation of cellular respiration(GO:0043457)
0.0	0.2	GO:0006177	GMP biosynthetic process(GO:0006177)
0.0	0.1	GO:0051459	corticotropin secretion(GO:0051458) regulation of corticotropin secretion(GO:0051459) positive regulation of corticotropin secretion(GO:0051461)
0.0	0.1	GO:0034204	lipid translocation(GO:0034204) phospholipid translocation(GO:0045332)
0.0	0.2	GO:0050687	negative regulation of defense response to virus(GO:0050687)
0.0	0.2	GO:0060263	regulation of respiratory burst(GO:0060263)
0.0	0.3	GO:0010872	regulation of cholesterol esterification(GO:0010872)
0.0	0.1	GO:0032811	negative regulation of epinephrine secretion(GO:0032811)
0.0	0.1	GO:0030187	melatonin metabolic process(GO:0030186) melatonin biosynthetic process(GO:0030187)
0.0	0.1	GO:0071698	olfactory placode formation(GO:0030910) olfactory placode development(GO:0071698) olfactory placode morphogenesis(GO:0071699)
0.0	0.1	GO:0008628	hormone-mediated apoptotic signaling pathway(GO:0008628)
0.0	0.1	GO:0051447	negative regulation of meiotic cell cycle(GO:0051447)
0.0	0.2	GO:1903672	positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050) positive regulation of sprouting angiogenesis(GO:1903672)
0.0	0.1	GO:0006667	sphinganine metabolic process(GO:0006667)
0.0	0.1	GO:0018343	protein farnesylation(GO:0018343)
0.0	0.1	GO:0048488	synaptic vesicle recycling(GO:0036465) synaptic vesicle endocytosis(GO:0048488) clathrin-mediated endocytosis(GO:0072583)
0.0	0.1	GO:0032959	inositol trisphosphate biosynthetic process(GO:0032959)
0.0	0.1	GO:0018101	protein citrullination(GO:0018101)
0.0	0.1	GO:0035025	positive regulation of Rho protein signal transduction(GO:0035025)
0.0	0.1	GO:0015919	peroxisomal membrane transport(GO:0015919)
0.0	0.1	GO:0060528	secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development(GO:0060528)
0.0	0.1	GO:0060836	lymphatic endothelial cell differentiation(GO:0060836)
0.0	0.1	GO:0002903	negative regulation of B cell apoptotic process(GO:0002903)
0.0	0.1	GO:0003100	regulation of systemic arterial blood pressure by endothelin(GO:0003100)
0.0	0.1	GO:0006432	phenylalanyl-tRNA aminoacylation(GO:0006432)
0.0	0.1	GO:0009414	response to water deprivation(GO:0009414) response to water(GO:0009415)
0.0	0.1	GO:0006102	isocitrate metabolic process(GO:0006102)
0.0	0.1	GO:0019987	obsolete negative regulation of anti-apoptosis(GO:0019987)
0.0	0.1	GO:0072531	pyrimidine-containing compound transmembrane transport(GO:0072531)
0.0	0.1	GO:0061004	pattern specification involved in kidney development(GO:0061004) renal system pattern specification(GO:0072048)
0.0	0.1	GO:0022605	oogenesis stage(GO:0022605)
0.0	0.3	GO:0006386	transcription elongation from RNA polymerase III promoter(GO:0006385) termination of RNA polymerase III transcription(GO:0006386)
0.0	0.1	GO:0006435	threonyl-tRNA aminoacylation(GO:0006435)
0.0	0.1	GO:0043369	alpha-beta T cell lineage commitment(GO:0002363) CD4-positive or CD8-positive, alpha-beta T cell lineage commitment(GO:0043369)
0.0	0.1	GO:0006686	sphingomyelin biosynthetic process(GO:0006686)
0.0	0.1	GO:0010459	negative regulation of heart rate(GO:0010459)
0.0	0.3	GO:0071514	genetic imprinting(GO:0071514)
0.0	0.1	GO:0010831	positive regulation of myotube differentiation(GO:0010831)
0.0	0.1	GO:0007181	transforming growth factor beta receptor complex assembly(GO:0007181)
0.0	0.1	GO:0016080	synaptic vesicle targeting(GO:0016080)
0.0	0.3	GO:0000303	response to superoxide(GO:0000303)
0.0	0.1	GO:0045722	positive regulation of gluconeogenesis(GO:0045722)
0.0	0.1	GO:0045988	negative regulation of striated muscle contraction(GO:0045988)
0.0	0.1	GO:0045618	positive regulation of keratinocyte differentiation(GO:0045618)
0.0	0.1	GO:0006003	fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.0	0.1	GO:0072393	microtubule anchoring at microtubule organizing center(GO:0072393)
0.0	0.1	GO:0070682	proteasome regulatory particle assembly(GO:0070682)
0.0	0.1	GO:0001672	regulation of chromatin assembly or disassembly(GO:0001672)
0.0	0.1	GO:0009299	mRNA transcription(GO:0009299)
0.0	0.1	GO:0006308	DNA catabolic process(GO:0006308)
0.0	0.0	GO:0046548	retinal rod cell development(GO:0046548)
0.0	0.2	GO:0002089	lens morphogenesis in camera-type eye(GO:0002089)
0.0	0.1	GO:0019441	tryptophan catabolic process to kynurenine(GO:0019441)
0.0	0.1	GO:0032506	cytokinetic process(GO:0032506)
0.0	0.2	GO:0000183	chromatin silencing at rDNA(GO:0000183)
0.0	0.1	GO:0051290	protein heterotetramerization(GO:0051290)
0.0	0.0	GO:0030538	embryonic genitalia morphogenesis(GO:0030538)
0.0	0.1	GO:0010508	positive regulation of autophagy(GO:0010508)
0.0	0.0	GO:0051136	NK T cell differentiation(GO:0001865) regulation of NK T cell differentiation(GO:0051136) positive regulation of NK T cell differentiation(GO:0051138)
0.0	0.1	GO:0046149	porphyrin-containing compound catabolic process(GO:0006787) tetrapyrrole catabolic process(GO:0033015) heme catabolic process(GO:0042167) pigment catabolic process(GO:0046149)
0.0	0.3	GO:0007176	regulation of epidermal growth factor-activated receptor activity(GO:0007176)
0.0	0.0	GO:0001705	ectoderm formation(GO:0001705)
0.0	0.0	GO:0010715	regulation of extracellular matrix disassembly(GO:0010715) negative regulation of extracellular matrix disassembly(GO:0010716) regulation of extracellular matrix organization(GO:1903053) negative regulation of extracellular matrix organization(GO:1903054)
0.0	0.0	GO:0061030	epithelial cell differentiation involved in mammary gland alveolus development(GO:0061030)
0.0	0.0	GO:0071692	sequestering of extracellular ligand from receptor(GO:0035581) sequestering of TGFbeta in extracellular matrix(GO:0035583) protein localization to extracellular region(GO:0071692) maintenance of protein location in extracellular region(GO:0071694) extracellular regulation of signal transduction(GO:1900115) extracellular negative regulation of signal transduction(GO:1900116)
0.0	0.1	GO:0001675	acrosome assembly(GO:0001675)
0.0	0.2	GO:0045116	protein neddylation(GO:0045116)
0.0	0.1	GO:0002281	macrophage activation involved in immune response(GO:0002281)
0.0	0.0	GO:0070561	vitamin D receptor signaling pathway(GO:0070561)
0.0	0.1	GO:0046185	aldehyde catabolic process(GO:0046185)
0.0	0.1	GO:0061430	bone trabecula formation(GO:0060346) bone trabecula morphogenesis(GO:0061430)
0.0	0.1	GO:0006528	asparagine metabolic process(GO:0006528)
0.0	0.1	GO:0034625	fatty acid elongation, monounsaturated fatty acid(GO:0034625)
0.0	0.1	GO:0042483	negative regulation of odontogenesis(GO:0042483)
0.0	0.1	GO:0032715	negative regulation of interleukin-6 production(GO:0032715)
0.0	0.1	GO:0002430	complement receptor mediated signaling pathway(GO:0002430)
0.0	0.0	GO:0001661	conditioned taste aversion(GO:0001661)
0.0	0.3	GO:0034605	cellular response to heat(GO:0034605)
0.0	0.1	GO:0051016	barbed-end actin filament capping(GO:0051016)
0.0	0.0	GO:0002693	positive regulation of cellular extravasation(GO:0002693)
0.0	0.0	GO:0043096	adenine salvage(GO:0006168) purine nucleobase salvage(GO:0043096) adenine metabolic process(GO:0046083) adenine biosynthetic process(GO:0046084)
0.0	0.2	GO:0090181	regulation of cholesterol metabolic process(GO:0090181)
0.0	0.0	GO:0021938	smoothened signaling pathway involved in regulation of cerebellar granule cell precursor cell proliferation(GO:0021938)
0.0	0.1	GO:0009972	cytidine catabolic process(GO:0006216) cytidine deamination(GO:0009972) cytidine metabolic process(GO:0046087)
0.0	0.1	GO:0071318	cellular response to ATP(GO:0071318)
0.0	0.2	GO:0010324	phagocytosis, engulfment(GO:0006911) membrane invagination(GO:0010324)
0.0	0.1	GO:0048087	positive regulation of developmental pigmentation(GO:0048087)
0.0	0.1	GO:0007216	G-protein coupled glutamate receptor signaling pathway(GO:0007216)
0.0	0.1	GO:0036230	granulocyte activation(GO:0036230) neutrophil activation(GO:0042119)
0.0	0.1	GO:0071731	response to nitric oxide(GO:0071731)
0.0	0.3	GO:0032012	regulation of ARF protein signal transduction(GO:0032012)
0.0	0.1	GO:0021520	spinal cord motor neuron cell fate specification(GO:0021520)
0.0	0.0	GO:0017014	protein nitrosylation(GO:0017014) peptidyl-cysteine S-nitrosylation(GO:0018119)
0.0	0.0	GO:0003402	planar cell polarity pathway involved in axis elongation(GO:0003402)
0.0	0.0	GO:0061047	regulation of branching involved in lung morphogenesis(GO:0061046) positive regulation of branching involved in lung morphogenesis(GO:0061047)
0.0	0.1	GO:0045071	negative regulation of viral genome replication(GO:0045071)
0.0	0.1	GO:0042535	positive regulation of tumor necrosis factor biosynthetic process(GO:0042535)
0.0	0.1	GO:0002097	tRNA wobble base modification(GO:0002097) tRNA wobble uridine modification(GO:0002098) tRNA thio-modification(GO:0034227)
0.0	0.1	GO:0022614	membrane to membrane docking(GO:0022614)
0.0	0.1	GO:0048548	regulation of pinocytosis(GO:0048548)
0.0	0.1	GO:0060219	camera-type eye photoreceptor cell differentiation(GO:0060219)
0.0	0.0	GO:0045940	positive regulation of steroid metabolic process(GO:0045940)
0.0	0.0	GO:0007195	adenylate cyclase-inhibiting dopamine receptor signaling pathway(GO:0007195)
0.0	0.1	GO:0016540	protein autoprocessing(GO:0016540)
0.0	0.2	GO:0000381	regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.0	0.0	GO:0021529	spinal cord oligodendrocyte cell differentiation(GO:0021529) spinal cord oligodendrocyte cell fate specification(GO:0021530) oligodendrocyte cell fate specification(GO:0021778) glial cell fate specification(GO:0021780)
0.0	0.0	GO:0051775	response to redox state(GO:0051775)
0.0	0.1	GO:0032328	alanine transport(GO:0032328)
0.0	0.4	GO:2000117	negative regulation of cysteine-type endopeptidase activity(GO:2000117)
0.0	0.0	GO:0060586	multicellular organismal iron ion homeostasis(GO:0060586)
0.0	0.1	GO:0008588	release of cytoplasmic sequestered NF-kappaB(GO:0008588)
0.0	0.0	GO:0072678	T cell migration(GO:0072678)
0.0	0.0	GO:0070874	negative regulation of glycogen metabolic process(GO:0070874)
0.0	0.1	GO:0007256	activation of JNKK activity(GO:0007256)
0.0	0.1	GO:1903556	negative regulation of tumor necrosis factor production(GO:0032720) negative regulation of tumor necrosis factor superfamily cytokine production(GO:1903556)
0.0	0.1	GO:0032876	regulation of DNA endoreduplication(GO:0032875) negative regulation of DNA endoreduplication(GO:0032876) DNA endoreduplication(GO:0042023)
0.0	0.1	GO:0046719	intracellular transport of viral protein in host cell(GO:0019060) symbiont intracellular protein transport in host(GO:0030581) regulation by virus of viral protein levels in host cell(GO:0046719) intracellular protein transport in other organism involved in symbiotic interaction(GO:0051708)
0.0	0.0	GO:0001831	trophectodermal cellular morphogenesis(GO:0001831)
0.0	0.1	GO:0043984	histone H4-K16 acetylation(GO:0043984)
0.0	0.2	GO:0043278	response to isoquinoline alkaloid(GO:0014072) response to morphine(GO:0043278)
0.0	0.1	GO:0046826	negative regulation of protein export from nucleus(GO:0046826)
0.0	0.1	GO:0002438	acute inflammatory response to antigenic stimulus(GO:0002438)
0.0	0.1	GO:0045348	positive regulation of MHC class II biosynthetic process(GO:0045348)
0.0	0.0	GO:0010916	regulation of very-low-density lipoprotein particle clearance(GO:0010915) negative regulation of very-low-density lipoprotein particle clearance(GO:0010916)
0.0	0.1	GO:0006670	sphingosine metabolic process(GO:0006670)
0.0	0.0	GO:0070230	positive regulation of lymphocyte apoptotic process(GO:0070230)
0.0	0.1	GO:1901072	amino sugar catabolic process(GO:0046348) glucosamine-containing compound catabolic process(GO:1901072)
0.0	0.1	GO:0006065	UDP-glucuronate biosynthetic process(GO:0006065)
0.0	0.1	GO:0051489	regulation of filopodium assembly(GO:0051489)
0.0	0.1	GO:0006269	DNA replication, synthesis of RNA primer(GO:0006269)
0.0	0.1	GO:0009804	phenylpropanoid metabolic process(GO:0009698) coumarin metabolic process(GO:0009804)
0.0	0.1	GO:0030263	apoptotic chromosome condensation(GO:0030263)
0.0	0.1	GO:0010288	response to lead ion(GO:0010288)
0.0	0.3	GO:0006611	protein export from nucleus(GO:0006611)
0.0	0.1	GO:0051001	negative regulation of nitric-oxide synthase activity(GO:0051001)
0.0	0.1	GO:0006684	sphingomyelin metabolic process(GO:0006684)
0.0	0.2	GO:0048489	synaptic vesicle transport(GO:0048489) synaptic vesicle localization(GO:0097479) establishment of synaptic vesicle localization(GO:0097480)
0.0	0.1	GO:0043171	peptide catabolic process(GO:0043171)
0.0	0.1	GO:0045767	obsolete regulation of anti-apoptosis(GO:0045767)
0.0	0.2	GO:0070536	protein K63-linked deubiquitination(GO:0070536)
0.0	0.1	GO:0031442	regulation of mRNA 3'-end processing(GO:0031440) positive regulation of mRNA 3'-end processing(GO:0031442) positive regulation of mRNA processing(GO:0050685) positive regulation of mRNA metabolic process(GO:1903313)
0.0	0.1	GO:0060317	cardiac epithelial to mesenchymal transition(GO:0060317)
0.0	0.3	GO:0018298	protein-chromophore linkage(GO:0018298)
0.0	0.1	GO:0060351	cartilage development involved in endochondral bone morphogenesis(GO:0060351)
0.0	0.4	GO:0046677	response to antibiotic(GO:0046677)
0.0	0.0	GO:0034371	chylomicron remodeling(GO:0034371)
0.0	0.0	GO:0019605	butyrate metabolic process(GO:0019605)
0.0	0.1	GO:0019885	antigen processing and presentation of endogenous peptide antigen(GO:0002483) antigen processing and presentation of endogenous peptide antigen via MHC class I(GO:0019885)
0.0	0.1	GO:0030259	lipid glycosylation(GO:0030259)
0.0	0.0	GO:1902624	positive regulation of neutrophil chemotaxis(GO:0090023) positive regulation of neutrophil migration(GO:1902624)
0.0	0.3	GO:0030010	establishment of cell polarity(GO:0030010)
0.0	0.3	GO:0030968	endoplasmic reticulum unfolded protein response(GO:0030968) cellular response to unfolded protein(GO:0034620)
0.0	0.0	GO:0032418	lysosome localization(GO:0032418)
0.0	1.2	GO:0035023	regulation of Rho protein signal transduction(GO:0035023)
0.0	0.0	GO:0031645	negative regulation of neurological system process(GO:0031645)
0.0	0.0	GO:1903115	regulation of muscle filament sliding(GO:0032971) regulation of actin filament-based movement(GO:1903115)
0.0	0.1	GO:0043353	enucleate erythrocyte differentiation(GO:0043353)
0.0	0.2	GO:0015721	bile acid and bile salt transport(GO:0015721)
0.0	0.1	GO:0007158	neuron cell-cell adhesion(GO:0007158)
0.0	0.1	GO:0005984	disaccharide metabolic process(GO:0005984)
0.0	0.1	GO:0015886	heme transport(GO:0015886)
0.0	0.0	GO:0003323	type B pancreatic cell development(GO:0003323)
0.0	0.0	GO:0022601	menstrual cycle phase(GO:0022601)
0.0	0.1	GO:0043518	negative regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043518) negative regulation of signal transduction by p53 class mediator(GO:1901797)
0.0	0.2	GO:0006359	regulation of transcription from RNA polymerase III promoter(GO:0006359)
0.0	0.0	GO:0045581	negative regulation of T cell differentiation(GO:0045581)
0.0	0.1	GO:0010890	positive regulation of sequestering of triglyceride(GO:0010890)
0.0	0.1	GO:0032733	positive regulation of interleukin-10 production(GO:0032733)
0.0	0.0	GO:0006701	progesterone biosynthetic process(GO:0006701)
0.0	0.0	GO:0032525	somite rostral/caudal axis specification(GO:0032525)
0.0	0.8	GO:0006921	cellular component disassembly involved in execution phase of apoptosis(GO:0006921) execution phase of apoptosis(GO:0097194)
0.0	0.1	GO:0045743	positive regulation of fibroblast growth factor receptor signaling pathway(GO:0045743)
0.0	0.4	GO:0043487	regulation of RNA stability(GO:0043487)
0.0	0.1	GO:0046716	muscle cell cellular homeostasis(GO:0046716)
0.0	0.0	GO:0031223	auditory behavior(GO:0031223)
0.0	0.1	GO:0045671	negative regulation of osteoclast differentiation(GO:0045671)
0.0	0.0	GO:0033505	floor plate morphogenesis(GO:0033505)
0.0	0.0	GO:0006998	nuclear envelope organization(GO:0006998)
0.0	0.9	GO:1904667	negative regulation of ubiquitin protein ligase activity(GO:1904667)
0.0	0.0	GO:0007638	mechanosensory behavior(GO:0007638)
0.0	0.1	GO:0050802	circadian sleep/wake cycle process(GO:0022410) circadian sleep/wake cycle, sleep(GO:0050802)
0.0	0.1	GO:0045730	respiratory burst(GO:0045730)
0.0	0.1	GO:0008356	asymmetric cell division(GO:0008356)
0.0	0.1	GO:0045737	positive regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045737) positive regulation of cyclin-dependent protein kinase activity(GO:1904031)
0.0	0.1	GO:0035092	sperm chromatin condensation(GO:0035092)
0.0	0.1	GO:0045006	DNA deamination(GO:0045006)
0.0	0.0	GO:0015742	alpha-ketoglutarate transport(GO:0015742)
0.0	0.1	GO:0000266	mitochondrial fission(GO:0000266)
0.0	0.1	GO:0051549	regulation of keratinocyte migration(GO:0051547) positive regulation of keratinocyte migration(GO:0051549)
0.0	0.0	GO:0032898	neurotrophin production(GO:0032898)
0.0	0.0	GO:0044320	cellular response to leptin stimulus(GO:0044320) response to leptin(GO:0044321)
0.0	0.0	GO:0002478	antigen processing and presentation of exogenous peptide antigen(GO:0002478)
0.0	0.0	GO:0032957	inositol trisphosphate metabolic process(GO:0032957)
0.0	0.0	GO:0032878	regulation of establishment or maintenance of cell polarity(GO:0032878)
0.0	0.1	GO:0010614	negative regulation of cardiac muscle hypertrophy(GO:0010614)
0.0	0.0	GO:0008631	intrinsic apoptotic signaling pathway in response to oxidative stress(GO:0008631) cell death in response to oxidative stress(GO:0036473)
0.0	0.1	GO:0032648	regulation of interferon-beta production(GO:0032648)
0.0	0.0	GO:0042118	endothelial cell activation(GO:0042118)
0.0	0.1	GO:0046487	glyoxylate metabolic process(GO:0046487)
0.0	0.0	GO:0019805	quinolinate biosynthetic process(GO:0019805)
0.0	0.0	GO:0035725	sodium ion transmembrane transport(GO:0035725) sodium ion export(GO:0071436)
0.0	0.0	GO:0042416	dopamine biosynthetic process(GO:0042416)
0.0	0.0	GO:0072677	eosinophil chemotaxis(GO:0048245) eosinophil migration(GO:0072677)
0.0	0.1	GO:0006107	oxaloacetate metabolic process(GO:0006107)
0.0	0.1	GO:0045885	obsolete positive regulation of survival gene product expression(GO:0045885)
0.0	0.0	GO:0060426	lung vasculature development(GO:0060426)
0.0	0.1	GO:0015884	folic acid transport(GO:0015884)
0.0	0.0	GO:0006166	purine ribonucleoside salvage(GO:0006166)
0.0	0.1	GO:0006422	aspartyl-tRNA aminoacylation(GO:0006422)
0.0	0.3	GO:0006071	glycerol metabolic process(GO:0006071)
0.0	0.0	GO:0006883	cellular sodium ion homeostasis(GO:0006883)
0.0	0.2	GO:0009226	nucleotide-sugar biosynthetic process(GO:0009226)
0.0	0.1	GO:0016572	histone phosphorylation(GO:0016572)
0.0	0.0	GO:0046639	negative regulation of alpha-beta T cell differentiation(GO:0046639)
0.0	0.1	GO:0015074	DNA integration(GO:0015074)
0.0	0.1	GO:0034370	triglyceride-rich lipoprotein particle remodeling(GO:0034370) very-low-density lipoprotein particle remodeling(GO:0034372)
0.0	0.1	GO:0046831	regulation of RNA export from nucleus(GO:0046831)
0.0	0.1	GO:0000076	DNA replication checkpoint(GO:0000076)
0.0	0.0	GO:0042726	flavin-containing compound metabolic process(GO:0042726)
0.0	0.1	GO:0051568	histone H3-K4 methylation(GO:0051568)
0.0	0.0	GO:0033119	negative regulation of RNA splicing(GO:0033119)
0.0	0.0	GO:0002313	mature B cell differentiation involved in immune response(GO:0002313)
0.0	0.0	GO:0042149	cellular response to glucose starvation(GO:0042149)
0.0	0.1	GO:0031648	protein destabilization(GO:0031648)
0.0	0.0	GO:0048537	mucosal-associated lymphoid tissue development(GO:0048537)
0.0	0.0	GO:0035284	central nervous system segmentation(GO:0035283) brain segmentation(GO:0035284)
0.0	0.1	GO:0043252	sodium-independent organic anion transport(GO:0043252)
0.0	0.0	GO:0045836	positive regulation of meiotic nuclear division(GO:0045836) positive regulation of meiotic cell cycle(GO:0051446)
0.0	0.1	GO:0043949	regulation of cAMP-mediated signaling(GO:0043949)
0.0	0.0	GO:0061054	dermatome development(GO:0061054)
0.0	0.0	GO:1901021	positive regulation of calcium ion transmembrane transporter activity(GO:1901021) positive regulation of cation channel activity(GO:2001259)
0.0	0.1	GO:0009435	NAD biosynthetic process(GO:0009435)
0.0	0.2	GO:0006957	complement activation, alternative pathway(GO:0006957)
0.0	0.0	GO:0045715	negative regulation of low-density lipoprotein particle receptor biosynthetic process(GO:0045715)
0.0	0.2	GO:0043124	negative regulation of I-kappaB kinase/NF-kappaB signaling(GO:0043124)
0.0	0.0	GO:0022617	extracellular matrix disassembly(GO:0022617)
0.0	0.1	GO:0000038	very long-chain fatty acid metabolic process(GO:0000038)
0.0	0.0	GO:0071801	regulation of podosome assembly(GO:0071801) positive regulation of podosome assembly(GO:0071803)
0.0	0.0	GO:0015670	carbon dioxide transport(GO:0015670)
0.0	0.0	GO:0070779	D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
0.0	0.1	GO:0032988	ribonucleoprotein complex disassembly(GO:0032988)
0.0	0.0	GO:0016265	obsolete death(GO:0016265)
0.0	0.0	GO:0045070	positive regulation of viral genome replication(GO:0045070)
0.0	0.0	GO:0060972	left/right pattern formation(GO:0060972)
0.0	0.0	GO:0006106	fumarate metabolic process(GO:0006106)
0.0	0.0	GO:0035520	monoubiquitinated protein deubiquitination(GO:0035520)
0.0	0.0	GO:0071636	positive regulation of transforming growth factor beta production(GO:0071636)
0.0	0.1	GO:0030851	granulocyte differentiation(GO:0030851)
0.0	0.5	GO:0016579	protein deubiquitination(GO:0016579)
0.0	0.3	GO:0006626	protein targeting to mitochondrion(GO:0006626)
0.0	0.0	GO:0006828	manganese ion transport(GO:0006828)
0.0	0.0	GO:0046689	response to mercury ion(GO:0046689)
0.0	0.0	GO:0048240	sperm capacitation(GO:0048240)
0.0	0.2	GO:0007076	mitotic chromosome condensation(GO:0007076)
0.0	0.0	GO:2000188	regulation of cholesterol homeostasis(GO:2000188) positive regulation of cholesterol homeostasis(GO:2000189)
0.0	0.1	GO:0040023	establishment of nucleus localization(GO:0040023)
0.0	0.1	GO:0043508	negative regulation of JUN kinase activity(GO:0043508)
0.0	0.0	GO:0031125	rRNA 3'-end processing(GO:0031125)
0.0	0.0	GO:0046968	peptide antigen transport(GO:0046968)
0.0	0.1	GO:0070493	thrombin receptor signaling pathway(GO:0070493)
0.0	0.1	GO:0031293	membrane protein intracellular domain proteolysis(GO:0031293)
0.0	0.0	GO:2000344	positive regulation of acrosome reaction(GO:2000344)
0.0	0.0	GO:0031580	membrane raft polarization(GO:0001766) membrane raft distribution(GO:0031580) membrane raft localization(GO:0051665)
0.0	0.0	GO:0010591	regulation of lamellipodium assembly(GO:0010591)
0.0	0.1	GO:0045880	positive regulation of smoothened signaling pathway(GO:0045880)
0.0	0.1	GO:0006607	NLS-bearing protein import into nucleus(GO:0006607)
0.0	0.0	GO:0017085	response to insecticide(GO:0017085)
0.0	0.1	GO:0006378	mRNA polyadenylation(GO:0006378)
0.0	0.0	GO:0043268	positive regulation of potassium ion transport(GO:0043268)
0.0	0.0	GO:0060397	JAK-STAT cascade involved in growth hormone signaling pathway(GO:0060397)
0.0	0.2	GO:0016339	calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.0	0.0	GO:0050930	induction of positive chemotaxis(GO:0050930)
0.0	0.1	GO:0071331	cellular response to monosaccharide stimulus(GO:0071326) cellular response to hexose stimulus(GO:0071331) cellular response to glucose stimulus(GO:0071333)
0.0	0.0	GO:0050849	negative regulation of calcium-mediated signaling(GO:0050849)
0.0	0.0	GO:0048147	negative regulation of fibroblast proliferation(GO:0048147)
0.0	0.0	GO:1904063	negative regulation of cation transmembrane transport(GO:1904063)
0.0	0.0	GO:0042448	progesterone metabolic process(GO:0042448)
0.0	0.0	GO:0007144	female meiosis I(GO:0007144)
0.0	0.0	GO:0043092	L-amino acid import(GO:0043092) L-glutamate import(GO:0051938)
0.0	0.1	GO:0031272	pseudopodium assembly(GO:0031269) regulation of pseudopodium assembly(GO:0031272) positive regulation of pseudopodium assembly(GO:0031274)
0.0	0.0	GO:0046398	UDP-glucuronate metabolic process(GO:0046398)
0.0	0.0	GO:0006498	N-terminal protein lipidation(GO:0006498)
0.0	0.0	GO:0032048	phosphatidylglycerol biosynthetic process(GO:0006655) cardiolipin metabolic process(GO:0032048) cardiolipin biosynthetic process(GO:0032049) phosphatidylglycerol metabolic process(GO:0046471)
0.0	0.0	GO:0033522	histone H2A ubiquitination(GO:0033522)
0.0	0.1	GO:0030206	chondroitin sulfate biosynthetic process(GO:0030206)
0.0	0.1	GO:0007157	heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)
0.0	0.0	GO:0003077	obsolete negative regulation of diuresis(GO:0003077)
0.0	0.0	GO:0045943	positive regulation of transcription from RNA polymerase I promoter(GO:0045943)
0.0	0.0	GO:0035054	embryonic heart tube anterior/posterior pattern specification(GO:0035054)
0.0	0.1	GO:0006895	Golgi to endosome transport(GO:0006895) Golgi to vacuole transport(GO:0006896)
0.0	0.0	GO:0032509	endosome transport via multivesicular body sorting pathway(GO:0032509)
0.0	0.1	GO:0033687	osteoblast proliferation(GO:0033687)
0.0	0.0	GO:0002507	tolerance induction(GO:0002507)
0.0	0.0	GO:0014826	vein smooth muscle contraction(GO:0014826)
0.0	0.1	GO:0033619	membrane protein proteolysis(GO:0033619)
0.0	0.0	GO:0014009	glial cell proliferation(GO:0014009)
0.0	0.2	GO:0007405	neuroblast proliferation(GO:0007405)
0.0	0.1	GO:0045745	positive regulation of G-protein coupled receptor protein signaling pathway(GO:0045745)
0.0	0.0	GO:0007000	nucleolus organization(GO:0007000)
0.0	0.0	GO:0032647	interferon-alpha production(GO:0032607) regulation of interferon-alpha production(GO:0032647)
0.0	0.0	GO:0030903	notochord development(GO:0030903)
0.0	0.1	GO:0019317	fucose catabolic process(GO:0019317) L-fucose metabolic process(GO:0042354) L-fucose catabolic process(GO:0042355)
0.0	0.0	GO:0045964	positive regulation of catecholamine metabolic process(GO:0045915) positive regulation of dopamine metabolic process(GO:0045964)
0.0	0.0	GO:0032847	regulation of cellular pH reduction(GO:0032847) positive regulation of cellular pH reduction(GO:0032849)
0.0	0.1	GO:0048753	melanosome organization(GO:0032438) pigment granule organization(GO:0048753)
0.0	0.0	GO:0045723	positive regulation of fatty acid biosynthetic process(GO:0045723)
0.0	0.1	GO:0035121	obsolete tail morphogenesis(GO:0035121)
0.0	0.1	GO:0010039	response to iron ion(GO:0010039)
0.0	0.4	GO:0006968	cellular defense response(GO:0006968)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	0.5	GO:0071062	alphav-beta3 integrin-vitronectin complex(GO:0071062)
0.1	0.8	GO:0030673	axolemma(GO:0030673)
0.1	0.3	GO:0071818	BAT3 complex(GO:0071818) ER membrane insertion complex(GO:0072379)
0.1	0.2	GO:0032009	early phagosome(GO:0032009)
0.1	0.4	GO:0031527	filopodium membrane(GO:0031527)
0.1	0.3	GO:0016327	apicolateral plasma membrane(GO:0016327)
0.1	0.2	GO:0060200	clathrin-sculpted acetylcholine transport vesicle(GO:0060200) clathrin-sculpted acetylcholine transport vesicle membrane(GO:0060201)
0.0	0.2	GO:0070776	H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.0	0.6	GO:0005942	phosphatidylinositol 3-kinase complex(GO:0005942)
0.0	0.3	GO:0030677	nucleolar ribonuclease P complex(GO:0005655) ribonuclease P complex(GO:0030677) multimeric ribonuclease P complex(GO:0030681)
0.0	0.3	GO:0005915	zonula adherens(GO:0005915)
0.0	1.0	GO:0005796	Golgi lumen(GO:0005796)
0.0	0.1	GO:0072487	MSL complex(GO:0072487)
0.0	0.2	GO:0016342	catenin complex(GO:0016342)
0.0	0.2	GO:0033256	I-kappaB/NF-kappaB complex(GO:0033256)
0.0	0.2	GO:0044224	juxtaparanode region of axon(GO:0044224)
0.0	0.1	GO:0033553	rDNA heterochromatin(GO:0033553)
0.0	0.2	GO:0034451	centriolar satellite(GO:0034451)
0.0	0.1	GO:0005639	integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229) nuclear membrane part(GO:0044453)
0.0	0.1	GO:0042629	mast cell granule(GO:0042629)
0.0	0.2	GO:0005666	DNA-directed RNA polymerase III complex(GO:0005666)
0.0	0.1	GO:0043260	laminin-11 complex(GO:0043260)
0.0	1.2	GO:0022625	cytosolic large ribosomal subunit(GO:0022625)
0.0	0.4	GO:0001772	immunological synapse(GO:0001772)
0.0	0.1	GO:0045323	interleukin-1 receptor complex(GO:0045323)
0.0	0.1	GO:0000791	euchromatin(GO:0000791)
0.0	0.2	GO:0000796	condensin complex(GO:0000796)
0.0	0.2	GO:0001891	phagocytic cup(GO:0001891)
0.0	0.2	GO:0000931	gamma-tubulin large complex(GO:0000931) gamma-tubulin ring complex(GO:0008274)
0.0	0.1	GO:0043083	synaptic cleft(GO:0043083)
0.0	0.1	GO:0030061	mitochondrial crista(GO:0030061)
0.0	0.2	GO:0031616	spindle pole centrosome(GO:0031616)
0.0	0.1	GO:0030008	TRAPP complex(GO:0030008)
0.0	0.1	GO:0001527	microfibril(GO:0001527)
0.0	0.0	GO:0042105	alpha-beta T cell receptor complex(GO:0042105)
0.0	0.5	GO:0019005	SCF ubiquitin ligase complex(GO:0019005)
0.0	0.1	GO:0008540	proteasome regulatory particle, base subcomplex(GO:0008540)
0.0	0.1	GO:0000138	Golgi trans cisterna(GO:0000138)
0.0	0.1	GO:0036126	outer dense fiber(GO:0001520) sperm flagellum(GO:0036126)
0.0	0.1	GO:0031045	dense core granule(GO:0031045)
0.0	0.1	GO:0005784	Sec61 translocon complex(GO:0005784) translocon complex(GO:0071256)
0.0	0.1	GO:0005826	actomyosin contractile ring(GO:0005826)
0.0	0.1	GO:0072357	PTW/PP1 phosphatase complex(GO:0072357)
0.0	0.1	GO:0005838	proteasome regulatory particle(GO:0005838)
0.0	0.1	GO:0031205	endoplasmic reticulum Sec complex(GO:0031205)
0.0	0.2	GO:0008250	oligosaccharyltransferase complex(GO:0008250)
0.0	0.3	GO:0000314	organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.0	0.5	GO:0005680	anaphase-promoting complex(GO:0005680)
0.0	0.1	GO:0031306	intrinsic component of mitochondrial outer membrane(GO:0031306)
0.0	0.1	GO:0000300	obsolete peripheral to membrane of membrane fraction(GO:0000300)
0.0	0.1	GO:0031264	death-inducing signaling complex(GO:0031264)
0.0	0.1	GO:0044462	external encapsulating structure(GO:0030312) external encapsulating structure part(GO:0044462)
0.0	0.1	GO:0031235	intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.0	0.1	GO:0043190	ATP-binding cassette (ABC) transporter complex(GO:0043190)
0.0	0.1	GO:0008537	proteasome activator complex(GO:0008537)
0.0	0.5	GO:0030131	clathrin adaptor complex(GO:0030131)
0.0	0.2	GO:0035631	CD40 receptor complex(GO:0035631)
0.0	0.3	GO:0005871	kinesin complex(GO:0005871)
0.0	0.0	GO:0030934	anchoring collagen complex(GO:0030934)
0.0	0.0	GO:0032045	guanyl-nucleotide exchange factor complex(GO:0032045)
0.0	0.1	GO:0016589	NURF complex(GO:0016589)
0.0	0.0	GO:0000152	nuclear ubiquitin ligase complex(GO:0000152)
0.0	0.1	GO:0042589	zymogen granule membrane(GO:0042589)
0.0	0.1	GO:0005885	Arp2/3 protein complex(GO:0005885)
0.0	0.1	GO:0070695	FHF complex(GO:0070695)
0.0	0.0	GO:0071438	invadopodium membrane(GO:0071438)
0.0	0.3	GO:0005913	cell-cell adherens junction(GO:0005913)
0.0	0.3	GO:0080008	Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.0	0.2	GO:0005858	axonemal dynein complex(GO:0005858)
0.0	0.0	GO:0014731	spectrin-associated cytoskeleton(GO:0014731)
0.0	0.1	GO:0043218	compact myelin(GO:0043218)
0.0	0.1	GO:0000242	pericentriolar material(GO:0000242)
0.0	0.1	GO:0005890	sodium:potassium-exchanging ATPase complex(GO:0005890)
0.0	0.1	GO:0016442	RISC complex(GO:0016442) RNAi effector complex(GO:0031332)
0.0	0.0	GO:0005594	collagen type IX trimer(GO:0005594)
0.0	0.1	GO:0034363	intermediate-density lipoprotein particle(GO:0034363)
0.0	0.0	GO:0016533	cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533)
0.0	0.7	GO:0000502	proteasome complex(GO:0000502)
0.0	0.0	GO:0005863	striated muscle myosin thick filament(GO:0005863)
0.0	0.1	GO:0001931	uropod(GO:0001931) cell trailing edge(GO:0031254)
0.0	0.2	GO:0005744	mitochondrial inner membrane presequence translocase complex(GO:0005744)
0.0	0.6	GO:0055037	recycling endosome(GO:0055037)
0.0	0.2	GO:0005665	DNA-directed RNA polymerase II, core complex(GO:0005665)
0.0	0.1	GO:0031092	platelet alpha granule membrane(GO:0031092)
0.0	0.0	GO:0032809	neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.0	0.1	GO:0005779	integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231)
0.0	0.1	GO:0031528	microvillus membrane(GO:0031528)
0.0	0.1	GO:0042382	paraspeckles(GO:0042382)
0.0	0.0	GO:0005797	Golgi medial cisterna(GO:0005797)
0.0	0.0	GO:0005686	U2 snRNP(GO:0005686)
0.0	1.6	GO:0031225	anchored component of membrane(GO:0031225)
0.0	0.0	GO:0060199	clathrin-sculpted glutamate transport vesicle(GO:0060199) clathrin-sculpted glutamate transport vesicle membrane(GO:0060203)
0.0	0.1	GO:0042599	lamellar body(GO:0042599)
0.0	0.0	GO:0005947	mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947)
0.0	0.1	GO:0005658	alpha DNA polymerase:primase complex(GO:0005658)
0.0	0.0	GO:0035327	transcriptionally active chromatin(GO:0035327)
0.0	0.1	GO:0048188	Set1C/COMPASS complex(GO:0048188)
0.0	0.0	GO:0031932	TORC2 complex(GO:0031932)
0.0	0.7	GO:0005643	nuclear pore(GO:0005643)
0.0	0.0	GO:0032133	chromosome passenger complex(GO:0032133)
0.0	0.2	GO:0016514	SWI/SNF complex(GO:0016514)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	0.7	GO:0016312	inositol bisphosphate phosphatase activity(GO:0016312)
0.2	0.7	GO:0043184	vascular endothelial growth factor receptor 2 binding(GO:0043184)
0.2	0.9	GO:0001609	G-protein coupled adenosine receptor activity(GO:0001609)
0.1	1.0	GO:0005114	type II transforming growth factor beta receptor binding(GO:0005114)
0.1	0.4	GO:0019958	C-X-C chemokine binding(GO:0019958) interleukin-8 binding(GO:0019959)
0.1	0.6	GO:0017176	phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.1	0.4	GO:0070492	oligosaccharide binding(GO:0070492)
0.1	0.5	GO:0052813	phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) phosphatidylinositol bisphosphate kinase activity(GO:0052813)
0.1	0.3	GO:0004911	interleukin-2 receptor activity(GO:0004911)
0.1	0.4	GO:0050815	phosphoserine binding(GO:0050815)
0.1	0.3	GO:0030151	molybdenum ion binding(GO:0030151)
0.1	0.3	GO:0033829	O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.1	0.2	GO:0050253	retinyl-palmitate esterase activity(GO:0050253)
0.1	0.2	GO:0035197	siRNA binding(GO:0035197)
0.1	0.2	GO:0008321	Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.1	0.4	GO:0043208	glycosphingolipid binding(GO:0043208)
0.1	0.2	GO:0032794	GTPase activating protein binding(GO:0032794)
0.1	0.2	GO:0004938	alpha2-adrenergic receptor activity(GO:0004938)
0.1	0.3	GO:0008296	3'-5'-exodeoxyribonuclease activity(GO:0008296)
0.1	0.3	GO:0030676	Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.1	0.2	GO:0070324	thyroid hormone binding(GO:0070324)
0.1	0.2	GO:0017112	Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.1	0.2	GO:0016882	cyclo-ligase activity(GO:0016882)
0.1	0.2	GO:0043141	ATP-dependent 5'-3' DNA helicase activity(GO:0043141)
0.1	0.2	GO:0033130	acetylcholine receptor binding(GO:0033130)
0.0	0.3	GO:0016290	palmitoyl-CoA hydrolase activity(GO:0016290)
0.0	0.2	GO:0015349	thyroid hormone transmembrane transporter activity(GO:0015349)
0.0	0.4	GO:0008889	glycerophosphodiester phosphodiesterase activity(GO:0008889)
0.0	0.1	GO:0019863	IgE binding(GO:0019863)
0.0	0.1	GO:0016309	1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
0.0	0.2	GO:0019911	structural constituent of myelin sheath(GO:0019911)
0.0	0.1	GO:0004886	9-cis retinoic acid receptor activity(GO:0004886)
0.0	0.2	GO:0009374	biotin binding(GO:0009374)
0.0	0.4	GO:0004029	aldehyde dehydrogenase (NAD) activity(GO:0004029)
0.0	0.2	GO:0004849	uridine kinase activity(GO:0004849)
0.0	0.1	GO:0005049	nuclear export signal receptor activity(GO:0005049)
0.0	0.1	GO:0035184	histone threonine kinase activity(GO:0035184)
0.0	0.1	GO:0004946	bombesin receptor activity(GO:0004946)
0.0	0.2	GO:0047023	androsterone dehydrogenase activity(GO:0047023)
0.0	0.1	GO:0052659	inositol-1,4,5-trisphosphate 5-phosphatase activity(GO:0052658) inositol-1,3,4,5-tetrakisphosphate 5-phosphatase activity(GO:0052659)
0.0	0.2	GO:0008526	phosphatidylinositol transporter activity(GO:0008526)
0.0	0.1	GO:0019788	NEDD8 transferase activity(GO:0019788)
0.0	0.2	GO:0030306	ADP-ribosylation factor binding(GO:0030306)
0.0	0.2	GO:0004969	histamine receptor activity(GO:0004969)
0.0	0.1	GO:0003886	DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.0	0.0	GO:0033691	sialic acid binding(GO:0033691)
0.0	0.2	GO:0005499	vitamin D binding(GO:0005499)
0.0	0.2	GO:0008020	G-protein coupled photoreceptor activity(GO:0008020)
0.0	0.1	GO:0035198	miRNA binding(GO:0035198)
0.0	0.1	GO:0016623	oxidoreductase activity, acting on the aldehyde or oxo group of donors, oxygen as acceptor(GO:0016623)
0.0	0.1	GO:0004663	Rab geranylgeranyltransferase activity(GO:0004663)
0.0	0.1	GO:0016286	small conductance calcium-activated potassium channel activity(GO:0016286)
0.0	0.1	GO:0042808	obsolete neuronal Cdc2-like kinase binding(GO:0042808)
0.0	0.2	GO:0001671	ATPase activator activity(GO:0001671)
0.0	0.2	GO:0004985	opioid receptor activity(GO:0004985)
0.0	0.1	GO:0004668	protein-arginine deiminase activity(GO:0004668)
0.0	0.3	GO:0016884	carbon-nitrogen ligase activity, with glutamine as amido-N-donor(GO:0016884)
0.0	0.1	GO:0004965	G-protein coupled GABA receptor activity(GO:0004965)
0.0	0.1	GO:0031782	melanocortin receptor binding(GO:0031779) type 3 melanocortin receptor binding(GO:0031781) type 4 melanocortin receptor binding(GO:0031782)
0.0	0.1	GO:0035252	UDP-xylosyltransferase activity(GO:0035252) xylosyltransferase activity(GO:0042285)
0.0	0.1	GO:0004994	somatostatin receptor activity(GO:0004994)
0.0	0.1	GO:0004448	isocitrate dehydrogenase activity(GO:0004448)
0.0	0.1	GO:0003836	beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.0	0.1	GO:0015037	peptide disulfide oxidoreductase activity(GO:0015037)
0.0	0.0	GO:0032036	myosin heavy chain binding(GO:0032036)
0.0	0.1	GO:0032296	ribonuclease III activity(GO:0004525) double-stranded RNA-specific ribonuclease activity(GO:0032296)
0.0	0.2	GO:0046790	virion binding(GO:0046790)
0.0	0.1	GO:0015925	galactosidase activity(GO:0015925)
0.0	0.1	GO:0008474	palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.0	0.1	GO:0000064	L-ornithine transmembrane transporter activity(GO:0000064)
0.0	0.1	GO:0004829	threonine-tRNA ligase activity(GO:0004829)
0.0	0.1	GO:0070097	delta-catenin binding(GO:0070097)
0.0	0.1	GO:0017081	chloride channel regulator activity(GO:0017081)
0.0	0.3	GO:0005031	tumor necrosis factor-activated receptor activity(GO:0005031)
0.0	0.1	GO:0004013	adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.0	0.2	GO:0004908	interleukin-1 receptor activity(GO:0004908)
0.0	0.1	GO:0043274	phospholipase binding(GO:0043274)
0.0	0.1	GO:0005332	gamma-aminobutyric acid:sodium symporter activity(GO:0005332)
0.0	0.1	GO:0070891	lipoteichoic acid binding(GO:0070891)
0.0	0.4	GO:0001540	beta-amyloid binding(GO:0001540)
0.0	0.1	GO:0008518	reduced folate carrier activity(GO:0008518)
0.0	0.4	GO:0005003	ephrin receptor activity(GO:0005003)
0.0	0.1	GO:0003873	6-phosphofructo-2-kinase activity(GO:0003873)
0.0	0.1	GO:0004826	phenylalanine-tRNA ligase activity(GO:0004826)
0.0	0.1	GO:0060228	phosphatidylcholine-sterol O-acyltransferase activator activity(GO:0060228)
0.0	0.1	GO:0001727	lipid kinase activity(GO:0001727)
0.0	0.2	GO:0043560	insulin receptor substrate binding(GO:0043560)
0.0	0.2	GO:0004526	ribonuclease P activity(GO:0004526)
0.0	0.0	GO:0008853	exodeoxyribonuclease III activity(GO:0008853)
0.0	0.1	GO:0015347	sodium-independent organic anion transmembrane transporter activity(GO:0015347)
0.0	0.4	GO:0043027	cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.0	0.1	GO:0015165	pyrimidine nucleotide-sugar transmembrane transporter activity(GO:0015165)
0.0	0.3	GO:0005095	GTPase inhibitor activity(GO:0005095)
0.0	0.1	GO:0016174	NAD(P)H oxidase activity(GO:0016174)
0.0	0.1	GO:0045545	syndecan binding(GO:0045545)
0.0	0.2	GO:0008242	omega peptidase activity(GO:0008242)
0.0	0.3	GO:0005251	delayed rectifier potassium channel activity(GO:0005251)
0.0	0.6	GO:0019843	rRNA binding(GO:0019843)
0.0	0.1	GO:0030197	extracellular matrix constituent, lubricant activity(GO:0030197)
0.0	0.1	GO:0004032	alditol:NADP+ 1-oxidoreductase activity(GO:0004032)
0.0	0.3	GO:0019534	toxin transporter activity(GO:0019534)
0.0	0.3	GO:0004708	MAP kinase kinase activity(GO:0004708)
0.0	0.3	GO:0051184	cofactor transporter activity(GO:0051184)
0.0	0.1	GO:0031705	bombesin receptor binding(GO:0031705) endothelin B receptor binding(GO:0031708)
0.0	0.1	GO:0004875	complement receptor activity(GO:0004875)
0.0	0.2	GO:0004622	lysophospholipase activity(GO:0004622)
0.0	0.2	GO:0016861	intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861)
0.0	0.0	GO:0003956	NAD(P)+-protein-arginine ADP-ribosyltransferase activity(GO:0003956)
0.0	0.1	GO:0043495	protein anchor(GO:0043495)
0.0	0.3	GO:0051537	2 iron, 2 sulfur cluster binding(GO:0051537)
0.0	0.0	GO:0000247	C-8 sterol isomerase activity(GO:0000247)
0.0	0.1	GO:0070577	lysine-acetylated histone binding(GO:0070577)
0.0	0.1	GO:0042153	obsolete RPTP-like protein binding(GO:0042153)
0.0	0.1	GO:0016717	oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water(GO:0016717)
0.0	0.2	GO:0003993	acid phosphatase activity(GO:0003993)
0.0	0.1	GO:0004126	cytidine deaminase activity(GO:0004126)
0.0	0.1	GO:0008199	ferric iron binding(GO:0008199)
0.0	0.1	GO:0004945	angiotensin receptor activity(GO:0001595) angiotensin type II receptor activity(GO:0004945)
0.0	0.0	GO:0005134	interleukin-2 receptor binding(GO:0005134)
0.0	0.1	GO:0004703	G-protein coupled receptor kinase activity(GO:0004703)
0.0	0.3	GO:0005086	ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0	0.2	GO:0008198	ferrous iron binding(GO:0008198)
0.0	0.0	GO:0004607	phosphatidylcholine-sterol O-acyltransferase activity(GO:0004607)
0.0	0.1	GO:0008504	monoamine transmembrane transporter activity(GO:0008504)
0.0	0.2	GO:0005522	profilin binding(GO:0005522)
0.0	0.1	GO:0008745	N-acetylmuramoyl-L-alanine amidase activity(GO:0008745) peptidoglycan receptor activity(GO:0016019)
0.0	0.1	GO:0017060	3-galactosyl-N-acetylglucosaminide 4-alpha-L-fucosyltransferase activity(GO:0017060)
0.0	0.1	GO:0005402	sugar:proton symporter activity(GO:0005351) cation:sugar symporter activity(GO:0005402)
0.0	0.1	GO:0042800	histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.0	0.0	GO:0005384	manganese ion transmembrane transporter activity(GO:0005384)
0.0	0.1	GO:0070064	proline-rich region binding(GO:0070064)
0.0	0.1	GO:0003726	double-stranded RNA adenosine deaminase activity(GO:0003726)
0.0	0.0	GO:0070326	very-low-density lipoprotein particle receptor binding(GO:0070326)
0.0	0.1	GO:0008327	methyl-CpG binding(GO:0008327)
0.0	0.1	GO:0016624	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor(GO:0016624)
0.0	0.1	GO:0015142	citrate transmembrane transporter activity(GO:0015137) tricarboxylic acid transmembrane transporter activity(GO:0015142)
0.0	0.4	GO:0001608	G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.0	0.1	GO:0015018	galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity(GO:0015018)
0.0	0.1	GO:0005521	lamin binding(GO:0005521)
0.0	0.2	GO:0005388	calcium-transporting ATPase activity(GO:0005388)
0.0	0.1	GO:0060590	ATPase regulator activity(GO:0060590)
0.0	0.1	GO:0019237	centromeric DNA binding(GO:0019237)
0.0	0.2	GO:0005487	nucleocytoplasmic transporter activity(GO:0005487)
0.0	0.1	GO:0008093	cytoskeletal adaptor activity(GO:0008093)
0.0	0.3	GO:0005164	tumor necrosis factor receptor binding(GO:0005164)
0.0	0.2	GO:0004579	dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.0	0.1	GO:0042392	sphingosine-1-phosphate phosphatase activity(GO:0042392)
0.0	0.1	GO:0031434	mitogen-activated protein kinase kinase binding(GO:0031434)
0.0	0.4	GO:0003950	NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.0	0.1	GO:0046870	cadmium ion binding(GO:0046870)
0.0	0.1	GO:0004697	protein kinase C activity(GO:0004697)
0.0	0.1	GO:0016417	S-acyltransferase activity(GO:0016417)
0.0	0.0	GO:0016748	succinyltransferase activity(GO:0016748)
0.0	0.1	GO:0004767	sphingomyelin phosphodiesterase activity(GO:0004767)
0.0	0.0	GO:0031849	olfactory receptor binding(GO:0031849)
0.0	0.1	GO:0008420	CTD phosphatase activity(GO:0008420)
0.0	0.0	GO:0042834	peptidoglycan binding(GO:0042834)
0.0	0.0	GO:0042799	histone methyltransferase activity (H4-K20 specific)(GO:0042799)
0.0	0.1	GO:0008131	primary amine oxidase activity(GO:0008131)
0.0	0.3	GO:0015459	potassium channel regulator activity(GO:0015459)
0.0	0.1	GO:0008140	cAMP response element binding protein binding(GO:0008140)
0.0	0.1	GO:0036041	long-chain fatty acid binding(GO:0036041)
0.0	0.1	GO:0008508	bile acid:sodium symporter activity(GO:0008508)
0.0	0.0	GO:0070576	vitamin D 24-hydroxylase activity(GO:0070576)
0.0	0.2	GO:0019865	immunoglobulin binding(GO:0019865)
0.0	0.5	GO:0004177	aminopeptidase activity(GO:0004177)
0.0	0.0	GO:0016728	ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
0.0	0.1	GO:0050700	CARD domain binding(GO:0050700)
0.0	1.0	GO:0005089	Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.0	0.2	GO:0008320	protein transmembrane transporter activity(GO:0008320)
0.0	0.0	GO:0046625	sphingolipid binding(GO:0046625)
0.0	0.1	GO:0008073	ornithine decarboxylase inhibitor activity(GO:0008073)
0.0	0.1	GO:0017080	sodium channel regulator activity(GO:0017080)
0.0	0.1	GO:0001517	N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517)
0.0	0.2	GO:0005246	calcium channel regulator activity(GO:0005246)
0.0	0.6	GO:0004722	protein serine/threonine phosphatase activity(GO:0004722)
0.0	0.0	GO:0043175	RNA polymerase core enzyme binding(GO:0043175)
0.0	0.1	GO:0034593	phosphatidylinositol bisphosphate phosphatase activity(GO:0034593)
0.0	0.2	GO:0004190	aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001)
0.0	0.1	GO:0004815	aspartate-tRNA ligase activity(GO:0004815)
0.0	0.0	GO:0015185	gamma-aminobutyric acid transmembrane transporter activity(GO:0015185)
0.0	0.1	GO:0005068	transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.0	0.1	GO:0005432	calcium:sodium antiporter activity(GO:0005432)
0.0	0.1	GO:0044390	ubiquitin conjugating enzyme binding(GO:0031624) ubiquitin-like protein conjugating enzyme binding(GO:0044390)
0.0	0.1	GO:0030296	protein tyrosine kinase activator activity(GO:0030296)
0.0	0.4	GO:0002039	p53 binding(GO:0002039)
0.0	0.0	GO:0033743	peptide-methionine (R)-S-oxide reductase activity(GO:0033743)
0.0	0.1	GO:0004630	phospholipase D activity(GO:0004630)
0.0	0.1	GO:0070008	serine-type exopeptidase activity(GO:0070008)
0.0	0.0	GO:0004082	bisphosphoglycerate mutase activity(GO:0004082) bisphosphoglycerate 2-phosphatase activity(GO:0004083) phosphoglycerate mutase activity(GO:0004619) bisphosphoglycerate phosphatase activity(GO:0034416)
0.0	0.1	GO:0003711	obsolete transcription elongation regulator activity(GO:0003711)
0.0	0.1	GO:0000339	RNA cap binding(GO:0000339)
0.0	0.1	GO:0004749	ribose phosphate diphosphokinase activity(GO:0004749)
0.0	0.1	GO:0005391	sodium:potassium-exchanging ATPase activity(GO:0005391)
0.0	0.1	GO:0034979	NAD-dependent histone deacetylase activity(GO:0017136) NAD-dependent protein deacetylase activity(GO:0034979)
0.0	0.2	GO:0016628	oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor(GO:0016628)
0.0	0.1	GO:0008440	inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440) inositol trisphosphate kinase activity(GO:0051766)
0.0	0.1	GO:0005219	ryanodine-sensitive calcium-release channel activity(GO:0005219)
0.0	0.1	GO:0050733	RS domain binding(GO:0050733)
0.0	0.0	GO:0016997	exo-alpha-sialidase activity(GO:0004308) alpha-sialidase activity(GO:0016997)
0.0	0.1	GO:0016813	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
0.0	0.1	GO:0004568	chitinase activity(GO:0004568)
0.0	0.1	GO:0070402	NADPH binding(GO:0070402)
0.0	0.0	GO:0015252	hydrogen ion channel activity(GO:0015252)
0.0	0.0	GO:0030911	TPR domain binding(GO:0030911)
0.0	0.0	GO:0045159	myosin II binding(GO:0045159)
0.0	0.0	GO:0005497	androgen binding(GO:0005497)
0.0	0.0	GO:0017150	tRNA dihydrouridine synthase activity(GO:0017150)
0.0	0.1	GO:0046920	alpha-(1->3)-fucosyltransferase activity(GO:0046920)
0.0	0.2	GO:0031683	G-protein beta/gamma-subunit complex binding(GO:0031683)
0.0	0.1	GO:0016653	oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor(GO:0016653)
0.0	0.1	GO:0016520	growth hormone-releasing hormone receptor activity(GO:0016520)
0.0	0.1	GO:0030020	extracellular matrix structural constituent conferring tensile strength(GO:0030020)
0.0	0.0	GO:0035173	histone kinase activity(GO:0035173)
0.0	0.0	GO:0015194	L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.0	0.1	GO:0017025	TBP-class protein binding(GO:0017025)
0.0	0.0	GO:0046974	histone methyltransferase activity (H3-K9 specific)(GO:0046974)
0.0	0.0	GO:0004339	glucan 1,4-alpha-glucosidase activity(GO:0004339)
0.0	0.1	GO:0043395	heparan sulfate proteoglycan binding(GO:0043395)
0.0	0.2	GO:0004683	calmodulin-dependent protein kinase activity(GO:0004683)
0.0	0.1	GO:0015377	cation:chloride symporter activity(GO:0015377)
0.0	0.0	GO:0008510	sodium:bicarbonate symporter activity(GO:0008510)
0.0	0.0	GO:0008332	low voltage-gated calcium channel activity(GO:0008332)
0.0	0.0	GO:0004999	vasoactive intestinal polypeptide receptor activity(GO:0004999)
0.0	0.1	GO:0000062	fatty-acyl-CoA binding(GO:0000062)
0.0	1.0	GO:0017124	SH3 domain binding(GO:0017124)
0.0	0.1	GO:0031210	phosphatidylcholine binding(GO:0031210)
0.0	0.1	GO:0004726	non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.0	0.1	GO:0050664	oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor(GO:0050664)
0.0	0.0	GO:0048020	CCR chemokine receptor binding(GO:0048020)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	1.5	SA MMP CYTOKINE CONNECTION	Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0	0.0	SIG BCR SIGNALING PATHWAY	Members of the BCR signaling pathway
0.0	0.5	PID IL8 CXCR2 PATHWAY	IL8- and CXCR2-mediated signaling events
0.0	2.2	PID PI3KCI PATHWAY	Class I PI3K signaling events
0.0	0.6	PID ANTHRAX PATHWAY	Cellular roles of Anthrax toxin
0.0	1.7	PID RHOA REG PATHWAY	Regulation of RhoA activity
0.0	0.8	PID LYMPH ANGIOGENESIS PATHWAY	VEGFR3 signaling in lymphatic endothelium
0.0	0.6	PID IL8 CXCR1 PATHWAY	IL8- and CXCR1-mediated signaling events
0.0	0.8	PID IL2 PI3K PATHWAY	IL2 signaling events mediated by PI3K
0.0	1.1	PID HIF2PATHWAY	HIF-2-alpha transcription factor network
0.0	0.2	ST IL 13 PATHWAY	Interleukin 13 (IL-13) Pathway
0.0	0.7	PID NECTIN PATHWAY	Nectin adhesion pathway
0.0	0.5	PID EPHRINB REV PATHWAY	Ephrin B reverse signaling
0.0	0.7	PID RAS PATHWAY	Regulation of Ras family activation
0.0	0.1	PID TCR RAS PATHWAY	Ras signaling in the CD4+ TCR pathway
0.0	0.9	PID VEGFR1 2 PATHWAY	Signaling events mediated by VEGFR1 and VEGFR2
0.0	0.0	ST PAC1 RECEPTOR PATHWAY	PAC1 Receptor Pathway
0.0	0.4	PID P38 MK2 PATHWAY	p38 signaling mediated by MAPKAP kinases
0.0	0.1	PID IL5 PATHWAY	IL5-mediated signaling events
0.0	0.1	PID RETINOIC ACID PATHWAY	Retinoic acid receptors-mediated signaling
0.0	0.3	ST ERK1 ERK2 MAPK PATHWAY	ERK1/ERK2 MAPK Pathway
0.0	0.0	PID IGF1 PATHWAY	IGF1 pathway
0.0	0.6	PID NFAT 3PATHWAY	Role of Calcineurin-dependent NFAT signaling in lymphocytes
0.0	0.1	PID P38 GAMMA DELTA PATHWAY	Signaling mediated by p38-gamma and p38-delta
0.0	0.1	PID ER NONGENOMIC PATHWAY	Plasma membrane estrogen receptor signaling
0.0	0.1	PID TCR JNK PATHWAY	JNK signaling in the CD4+ TCR pathway
0.0	0.1	PID NFKAPPAB ATYPICAL PATHWAY	Atypical NF-kappaB pathway
0.0	0.2	PID ERBB2 ERBB3 PATHWAY	ErbB2/ErbB3 signaling events
0.0	0.2	PID SYNDECAN 3 PATHWAY	Syndecan-3-mediated signaling events
0.0	0.3	PID INSULIN GLUCOSE PATHWAY	Insulin-mediated glucose transport
0.0	0.1	PID AVB3 OPN PATHWAY	Osteopontin-mediated events
0.0	0.1	PID IL27 PATHWAY	IL27-mediated signaling events
0.0	0.2	PID ECADHERIN NASCENT AJ PATHWAY	E-cadherin signaling in the nascent adherens junction
0.0	0.5	PID IL4 2PATHWAY	IL4-mediated signaling events
0.0	0.2	PID ALPHA SYNUCLEIN PATHWAY	Alpha-synuclein signaling
0.0	0.1	SIG CD40PATHWAYMAP	Genes related to CD40 signaling
0.0	0.4	PID TGFBR PATHWAY	TGF-beta receptor signaling
0.0	0.2	PID INTEGRIN A9B1 PATHWAY	Alpha9 beta1 integrin signaling events
0.0	0.1	ST TUMOR NECROSIS FACTOR PATHWAY	Tumor Necrosis Factor Pathway.
0.0	0.4	PID AR TF PATHWAY	Regulation of Androgen receptor activity
0.0	0.1	PID THROMBIN PAR4 PATHWAY	PAR4-mediated thrombin signaling events
0.0	0.2	ST T CELL SIGNAL TRANSDUCTION	T Cell Signal Transduction
0.0	0.2	PID PRL SIGNALING EVENTS PATHWAY	Signaling events mediated by PRL
0.0	0.2	PID ANGIOPOIETIN RECEPTOR PATHWAY	Angiopoietin receptor Tie2-mediated signaling
0.0	0.2	PID FAS PATHWAY	FAS (CD95) signaling pathway
0.0	0.0	PID TCR CALCIUM PATHWAY	Calcium signaling in the CD4+ TCR pathway
0.0	0.5	PID ERBB1 DOWNSTREAM PATHWAY	ErbB1 downstream signaling
0.0	0.1	PID PI3K PLC TRK PATHWAY	Trk receptor signaling mediated by PI3K and PLC-gamma
0.0	0.1	ST GRANULE CELL SURVIVAL PATHWAY	Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway.
0.0	0.2	PID WNT CANONICAL PATHWAY	Canonical Wnt signaling pathway
0.0	0.0	SIG PIP3 SIGNALING IN B LYMPHOCYTES	Genes related to PIP3 signaling in B lymphocytes
0.0	0.1	PID CD40 PATHWAY	CD40/CD40L signaling
0.0	0.1	PID AMB2 NEUTROPHILS PATHWAY	amb2 Integrin signaling
0.0	0.3	PID P75 NTR PATHWAY	p75(NTR)-mediated signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	1.2	REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION	Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.1	0.1	REACTOME SIGNALING BY ERBB2	Genes involved in Signaling by ERBB2
0.1	1.2	REACTOME NUCLEOTIDE LIKE PURINERGIC RECEPTORS	Genes involved in Nucleotide-like (purinergic) receptors
0.1	0.1	REACTOME CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE	Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
0.0	1.3	REACTOME IL RECEPTOR SHC SIGNALING	Genes involved in Interleukin receptor SHC signaling
0.0	1.0	REACTOME GPVI MEDIATED ACTIVATION CASCADE	Genes involved in GPVI-mediated activation cascade
0.0	0.4	REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING	Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
0.0	0.6	REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI	Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.0	0.7	REACTOME INHIBITION OF THE PROTEOLYTIC ACTIVITY OF APC C REQUIRED FOR THE ONSET OF ANAPHASE BY MITOTIC SPINDLE CHECKPOINT COMPONENTS	Genes involved in Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components
0.0	0.0	REACTOME SIGNALING BY FGFR IN DISEASE	Genes involved in Signaling by FGFR in disease
0.0	0.4	REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS	Genes involved in Apoptotic cleavage of cell adhesion proteins
0.0	0.0	REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS	Genes involved in Membrane binding and targetting of GAG proteins
0.0	0.0	REACTOME SCFSKP2 MEDIATED DEGRADATION OF P27 P21	Genes involved in SCF(Skp2)-mediated degradation of p27/p21
0.0	0.5	REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING	Genes involved in Downregulation of TGF-beta receptor signaling
0.0	0.3	REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS	Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.0	0.3	REACTOME P38MAPK EVENTS	Genes involved in p38MAPK events
0.0	0.2	REACTOME REGULATION OF SIGNALING BY CBL	Genes involved in Regulation of signaling by CBL
0.0	0.5	REACTOME ENOS ACTIVATION AND REGULATION	Genes involved in eNOS activation and regulation
0.0	0.0	REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN	Genes involved in Platelet Adhesion to exposed collagen
0.0	0.2	REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS	Genes involved in Facilitative Na+-independent glucose transporters
0.0	0.2	REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA	Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.0	0.1	REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING	Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.0	0.2	REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE	Genes involved in Norepinephrine Neurotransmitter Release Cycle
0.0	0.4	REACTOME THE ROLE OF NEF IN HIV1 REPLICATION AND DISEASE PATHOGENESIS	Genes involved in The role of Nef in HIV-1 replication and disease pathogenesis
0.0	0.4	REACTOME REGULATION OF HYPOXIA INDUCIBLE FACTOR HIF BY OXYGEN	Genes involved in Regulation of Hypoxia-inducible Factor (HIF) by Oxygen
0.0	0.0	REACTOME CDK MEDIATED PHOSPHORYLATION AND REMOVAL OF CDC6	Genes involved in CDK-mediated phosphorylation and removal of Cdc6
0.0	0.7	REACTOME SIGNAL TRANSDUCTION BY L1	Genes involved in Signal transduction by L1
0.0	0.2	REACTOME ACTIVATION OF RAC	Genes involved in Activation of Rac
0.0	0.4	REACTOME RNA POL III CHAIN ELONGATION	Genes involved in RNA Polymerase III Chain Elongation
0.0	0.4	REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS	Genes involved in Termination of O-glycan biosynthesis
0.0	0.1	REACTOME CS DS DEGRADATION	Genes involved in CS/DS degradation
0.0	0.3	REACTOME PRE NOTCH PROCESSING IN GOLGI	Genes involved in Pre-NOTCH Processing in Golgi
0.0	0.2	REACTOME EGFR DOWNREGULATION	Genes involved in EGFR downregulation
0.0	0.1	REACTOME RECYCLING PATHWAY OF L1	Genes involved in Recycling pathway of L1
0.0	0.0	REACTOME APC CDC20 MEDIATED DEGRADATION OF NEK2A	Genes involved in APC-Cdc20 mediated degradation of Nek2A
0.0	0.2	REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS	Genes involved in Tandem pore domain potassium channels
0.0	0.1	REACTOME NFKB ACTIVATION THROUGH FADD RIP1 PATHWAY MEDIATED BY CASPASE 8 AND10	Genes involved in NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10
0.0	0.5	REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING	Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.0	0.4	REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE	Genes involved in Sema4D induced cell migration and growth-cone collapse
0.0	0.3	REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS	Genes involved in ABCA transporters in lipid homeostasis
0.0	0.4	REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS	Genes involved in Apoptotic cleavage of cellular proteins
0.0	0.7	REACTOME AUTODEGRADATION OF CDH1 BY CDH1 APC C	Genes involved in Autodegradation of Cdh1 by Cdh1:APC/C
0.0	0.1	REACTOME RIP MEDIATED NFKB ACTIVATION VIA DAI	Genes involved in RIP-mediated NFkB activation via DAI
0.0	0.2	REACTOME METABOLISM OF PORPHYRINS	Genes involved in Metabolism of porphyrins
0.0	0.2	REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS	Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.0	0.2	REACTOME OPSINS	Genes involved in Opsins
0.0	0.8	REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES	Genes involved in Chemokine receptors bind chemokines
0.0	0.4	REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS	Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.0	0.6	REACTOME CELL DEATH SIGNALLING VIA NRAGE NRIF AND NADE	Genes involved in Cell death signalling via NRAGE, NRIF and NADE
0.0	0.1	REACTOME GENERATION OF SECOND MESSENGER MOLECULES	Genes involved in Generation of second messenger molecules
0.0	0.7	REACTOME MITOCHONDRIAL PROTEIN IMPORT	Genes involved in Mitochondrial Protein Import
0.0	0.4	REACTOME ADHERENS JUNCTIONS INTERACTIONS	Genes involved in Adherens junctions interactions
0.0	0.2	REACTOME ADENYLATE CYCLASE INHIBITORY PATHWAY	Genes involved in Adenylate cyclase inhibitory pathway
0.0	0.1	REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS	Genes involved in Signal regulatory protein (SIRP) family interactions
0.0	0.3	REACTOME TRAFFICKING OF AMPA RECEPTORS	Genes involved in Trafficking of AMPA receptors
0.0	0.1	REACTOME ROLE OF DCC IN REGULATING APOPTOSIS	Genes involved in Role of DCC in regulating apoptosis
0.0	0.1	REACTOME DSCAM INTERACTIONS	Genes involved in DSCAM interactions
0.0	0.1	REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION	Genes involved in activated TAK1 mediates p38 MAPK activation
0.0	0.1	REACTOME TIE2 SIGNALING	Genes involved in Tie2 Signaling
0.0	0.1	REACTOME HYALURONAN UPTAKE AND DEGRADATION	Genes involved in Hyaluronan uptake and degradation
0.0	0.6	REACTOME VOLTAGE GATED POTASSIUM CHANNELS	Genes involved in Voltage gated Potassium channels
0.0	0.1	REACTOME RECYCLING OF BILE ACIDS AND SALTS	Genes involved in Recycling of bile acids and salts
0.0	0.3	REACTOME CHOLESTEROL BIOSYNTHESIS	Genes involved in Cholesterol biosynthesis
0.0	0.7	REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES	Genes involved in Antiviral mechanism by IFN-stimulated genes
0.0	0.1	REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION	Genes involved in GABA synthesis, release, reuptake and degradation
0.0	0.0	REACTOME SIGNALING BY EGFR IN CANCER	Genes involved in Signaling by EGFR in Cancer
0.0	0.0	REACTOME G1 S TRANSITION	Genes involved in G1/S Transition
0.0	0.2	REACTOME SIGNALING BY FGFR1 FUSION MUTANTS	Genes involved in Signaling by FGFR1 fusion mutants
0.0	0.1	REACTOME TRANSPORT OF ORGANIC ANIONS	Genes involved in Transport of organic anions
0.0	0.6	REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY	Genes involved in Nuclear Receptor transcription pathway
0.0	0.1	REACTOME CELL CYCLE	Genes involved in Cell Cycle
0.0	0.1	REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING	Genes involved in Advanced glycosylation endproduct receptor signaling
0.0	0.2	REACTOME PEPTIDE HORMONE BIOSYNTHESIS	Genes involved in Peptide hormone biosynthesis
0.0	0.9	REACTOME PEPTIDE CHAIN ELONGATION	Genes involved in Peptide chain elongation
0.0	0.0	REACTOME ACETYLCHOLINE NEUROTRANSMITTER RELEASE CYCLE	Genes involved in Acetylcholine Neurotransmitter Release Cycle
0.0	0.0	REACTOME TRAF6 MEDIATED IRF7 ACTIVATION	Genes involved in TRAF6 mediated IRF7 activation
0.0	0.3	REACTOME KINESINS	Genes involved in Kinesins
0.0	0.5	REACTOME POTASSIUM CHANNELS	Genes involved in Potassium Channels
0.0	0.1	REACTOME CTNNB1 PHOSPHORYLATION CASCADE	Genes involved in Beta-catenin phosphorylation cascade
0.0	0.1	REACTOME SIGNAL ATTENUATION	Genes involved in Signal attenuation
0.0	0.1	REACTOME HIGHLY CALCIUM PERMEABLE POSTSYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS	Genes involved in Highly calcium permeable postsynaptic nicotinic acetylcholine receptors
0.0	0.5	REACTOME DEFENSINS	Genes involved in Defensins
0.0	0.1	REACTOME TRYPTOPHAN CATABOLISM	Genes involved in Tryptophan catabolism
0.0	0.0	REACTOME REGULATION OF GLUCOKINASE BY GLUCOKINASE REGULATORY PROTEIN	Genes involved in Regulation of Glucokinase by Glucokinase Regulatory Protein
0.0	0.5	REACTOME INTERFERON ALPHA BETA SIGNALING	Genes involved in Interferon alpha/beta signaling

Results for RAD21_SMC3

Z-value: 2.88

Motif logo

Transcription factors associated with RAD21_SMC3

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

Activity of the RAD21_SMC3 motif across conditions

Conditions sorted by the z-value of the RAD21_SMC3 motif activity

Top target CREs of the motif:

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of RAD21_SMC3

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category:

Gene overrepresentation in curated gene sets: canonical pathways category:

Gene overrepresentation in curated gene sets: REACTOME pathways category: