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ENCODE: H3K4me1 ChIP-Seq of primary human cells
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Results for RARB

Z-value: 1.29

Motif logo

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Transcription factors associated with RARB

Gene Symbol Gene ID Gene Info
RARB
ENSG00000077092.14 retinoic acid receptor beta

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE Gene Distance Association probability Pearson corr. coef. P-value Plot
chr3_25467445_25467596RARB22340.4148660.732.7e-02Click!
chr3_25469317_25469468RARB3620.918895-0.684.2e-02Click!
chr3_25468973_25469183RARB6760.795176-0.571.1e-01Click!
chr3_25502672_25502823RARB29460.361574-0.541.4e-01Click!
chr3_25515462_25515613RARB157360.2542920.491.8e-01Click!

Activity of the RARB motif across conditions

Conditions sorted by the z-value of the RARB motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE) Target Score Top associated gene Gene Info Distance of CRE to TSS CRE/Gene association probability
chr1_2201758_2202172 0.76 SKI
 v-ski avian sarcoma viral oncogene homolog
 41831
 0.09
chr1_51713251_51713402 0.51 RNF11
 ring finger protein 11
 11383
 0.14
chr17_37930387_37930595 0.37 IKZF3
 IKAROS family zinc finger 3 (Aiolos)
 3987
 0.16
chr6_149586290_149586441 0.37 RP1-111D6.2
21228
 0.17
chr9_111673666_111673817 0.35 IKBKAP
 inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase complex-associated protein
 22492
 0.14
chr12_92773237_92773489 0.35 RP11-693J15.4
41944
 0.15
chr16_84588398_84588684 0.34 TLDC1
 TBC/LysM-associated domain containing 1
 902
 0.58
chr6_106554306_106554551 0.34 RP1-134E15.3
6413
 0.24
chr3_112210012_112210199 0.34 BTLA
 B and T lymphocyte associated
 8100
 0.24
chr15_60856843_60856994 0.34 RORA
 RAR-related orphan receptor A
 27822
 0.16
chr2_231604805_231604956 0.33 ENSG00000201044
 .
 11976
 0.21
chr10_73843245_73843541 0.32 SPOCK2
 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2
 4693
 0.26
chr12_48547567_48547718 0.32 ASB8
 ankyrin repeat and SOCS box containing 8
 66
 0.96
chr9_136015803_136015954 0.32 RALGDS
 ral guanine nucleotide dissociation stimulator
 8843
 0.14
chr7_86831934_86832092 0.30 DMTF1
 cyclin D binding myb-like transcription factor 1
 8972
 0.18
chr16_57161336_57161487 0.30 CPNE2
 copine II
 8300
 0.15
chr2_98334024_98334251 0.30 ZAP70
 zeta-chain (TCR) associated protein kinase 70kDa
 4114
 0.2
chrX_78513523_78513700 0.30 GPR174
 G protein-coupled receptor 174
 87142
 0.1
chr11_68247646_68247864 0.30 PPP6R3
 protein phosphatase 6, regulatory subunit 3
 19474
 0.15
chrX_153541527_153541705 0.30 TKTL1
 transketolase-like 1
 8207
 0.1
chrX_153668216_153668410 0.30 GDI1
 GDP dissociation inhibitor 1
 3047
 0.09
chr1_116867881_116868032 0.30 ENSG00000221040
 .
 46728
 0.12
chr1_2203497_2203648 0.29 SKI
 v-ski avian sarcoma viral oncogene homolog
 43438
 0.08
chr6_138120638_138120789 0.29 ENSG00000207300
 .
 15202
 0.21
chr10_127673598_127673749 0.29 FANK1
 fibronectin type III and ankyrin repeat domains 1
 10209
 0.19
chr6_12115020_12115171 0.29 HIVEP1
 human immunodeficiency virus type I enhancer binding protein 1
 10884
 0.3
chr5_171340865_171341087 0.29 FBXW11
 F-box and WD repeat domain containing 11
 63784
 0.12
chr8_128222716_128223004 0.28 POU5F1B
 POU class 5 homeobox 1B
 203675
 0.03
chr6_35278431_35279308 0.28 DEF6
 differentially expressed in FDCP 6 homolog (mouse)
 1354
 0.42
chr16_89796408_89796559 0.28 ZNF276
 zinc finger protein 276
 8531
 0.1
chr22_30693496_30693647 0.28 RP1-130H16.18
 Uncharacterized protein
 1900
 0.19
chr6_126142988_126143327 0.28 NCOA7-AS1
 NCOA7 antisense RNA 1
 3153
 0.24
chrX_46471596_46471846 0.28 CHST7
 carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 7
 38502
 0.17
chr20_39387092_39387243 0.28 MAFB
 v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B
 69287
 0.13
chr19_45755493_45756253 0.28 MARK4
 MAP/microtubule affinity-regulating kinase 4
 1323
 0.34
chr10_32596747_32596901 0.28 RP11-166N17.3
26210
 0.12
chr6_112069480_112069631 0.28 FYN
 FYN oncogene related to SRC, FGR, YES
 10762
 0.26
chr9_100857599_100857750 0.28 TRIM14
 tripartite motif containing 14
 2831
 0.26
chr4_143502954_143503105 0.28 INPP4B
 inositol polyphosphate-4-phosphatase, type II, 105kDa
 21207
 0.3
chr1_10367885_10368145 0.28 ENSG00000264501
 .
 1492
 0.35
chr22_40327971_40328220 0.28 GRAP2
 GRB2-related adaptor protein 2
 5454
 0.19
chr2_10932773_10932924 0.27 PDIA6
 protein disulfide isomerase family A, member 6
 20032
 0.15
chrX_100085546_100085697 0.27 ENSG00000202231
 .
 7880
 0.17
chr6_138057394_138057545 0.27 ENSG00000216097
 .
 19384
 0.22
chr11_10043116_10043373 0.27 SBF2
 SET binding factor 2
 28593
 0.22
chr9_4596090_4596285 0.27 SLC1A1
 solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1
 23852
 0.19
chr1_32732695_32732890 0.27 LCK
 lymphocyte-specific protein tyrosine kinase
 6922
 0.09
chr1_111414550_111414730 0.27 CD53
 CD53 molecule
 1135
 0.52
chr5_169687872_169688139 0.26 LCP2
 lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa)
 6295
 0.24
chr1_192547343_192547494 0.26 RGS1
 regulator of G-protein signaling 1
 2515
 0.31
chr13_41186364_41186802 0.26 FOXO1
 forkhead box O1
 54151
 0.14
chr7_157419627_157419968 0.26 AC005481.5
 Uncharacterized protein
 13082
 0.23
chr7_130663484_130663779 0.26 LINC-PINT
 long intergenic non-protein coding RNA, p53 induced transcript
 5237
 0.29
chr4_110484863_110485014 0.26 CCDC109B
 coiled-coil domain containing 109B
 2792
 0.32
chr6_53101407_53101558 0.26 ENSG00000206908
 .
 17423
 0.17
chr2_175465978_175466202 0.26 WIPF1
 WAS/WASL interacting protein family, member 1
 3151
 0.24
chr2_114662697_114662848 0.26 ACTR3
 ARP3 actin-related protein 3 homolog (yeast)
 14597
 0.22
chr20_16715430_16715581 0.26 RP4-705D16.3
3912
 0.21
chr11_94667034_94667212 0.26 RP11-856F16.2
8437
 0.21
chr19_3094776_3095602 0.26 GNA11
 guanine nucleotide binding protein (G protein), alpha 11 (Gq class)
 781
 0.49
chr12_46918323_46918580 0.25 SLC38A2
 solute carrier family 38, member 2
 151801
 0.04
chr13_99967235_99967386 0.25 GPR183
 G protein-coupled receptor 183
 7651
 0.21
chr2_106356849_106357027 0.25 NCK2
 NCK adaptor protein 2
 4416
 0.34
chrX_48771847_48772324 0.25 PIM2
 pim-2 oncogene
 927
 0.37
chr2_162926034_162926185 0.25 AC008063.2
3657
 0.25
chr15_78398369_78398538 0.25 SH2D7
 SH2 domain containing 7
 13526
 0.12
chr3_125150854_125151005 0.25 ENSG00000238992
 .
 13976
 0.18
chr6_112088301_112088505 0.25 FYN
 FYN oncogene related to SRC, FGR, YES
 7283
 0.29
chr7_44486512_44486663 0.25 NUDCD3
 NudC domain containing 3
 43892
 0.13
chr6_146186713_146187159 0.25 SHPRH
 SNF2 histone linker PHD RING helicase, E3 ubiquitin protein ligase
 27554
 0.19
chr11_76863429_76863625 0.25 MYO7A
 myosin VIIA
 24179
 0.18
chr5_53821237_53821474 0.25 SNX18
 sorting nexin 18
 7762
 0.29
chr17_40552596_40552747 0.25 ENSG00000221020
 .
 1644
 0.25
chr17_37930930_37931081 0.25 IKZF3
 IKAROS family zinc finger 3 (Aiolos)
 3473
 0.17
chr6_128214587_128214749 0.25 THEMIS
 thymocyte selection associated
 7435
 0.31
chr6_119165676_119165988 0.25 MCM9
 minichromosome maintenance complex component 9
 15416
 0.23
chr2_46532768_46532919 0.25 EPAS1
 endothelial PAS domain protein 1
 8302
 0.28
chr5_49698412_49698563 0.25 EMB
 embigin
 26074
 0.28
chr7_30777555_30777817 0.25 INMT
 indolethylamine N-methyltransferase
 14065
 0.18
chr1_40857259_40857445 0.25 SMAP2
 small ArfGAP2
 5155
 0.19
chr19_19176974_19177125 0.25 SLC25A42
 solute carrier family 25, member 42
 2241
 0.21
chr9_92686685_92686836 0.25 ENSG00000263967
 .
 99057
 0.09
chr2_238338144_238338295 0.25 AC112721.1
 Uncharacterized protein
 4300
 0.23
chr18_60880832_60881273 0.24 ENSG00000238988
 .
 19154
 0.21
chr6_35336958_35337109 0.24 PPARD
 peroxisome proliferator-activated receptor delta
 26631
 0.16
chr13_50072819_50073075 0.24 PHF11
 PHD finger protein 11
 1698
 0.37
chr8_67523160_67523372 0.24 MYBL1
 v-myb avian myeloblastosis viral oncogene homolog-like 1
 1876
 0.32
chr21_16002379_16002642 0.24 AF165138.7
 Protein LOC388813
 12944
 0.23
chr2_69842302_69842453 0.24 AAK1
 AP2 associated kinase 1
 28409
 0.18
chrX_19845470_19845697 0.24 SH3KBP1
 SH3-domain kinase binding protein 1
 27714
 0.24
chr4_122836640_122836791 0.24 TRPC3
 transient receptor potential cation channel, subfamily C, member 3
 17478
 0.21
chr5_56189234_56189385 0.24 SETD9
 SET domain containing 9
 15778
 0.12
chr20_5574571_5574794 0.24 GPCPD1
 glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae)
 16990
 0.24
chrX_123475859_123476089 0.24 SH2D1A
 SH2 domain containing 1A
 4220
 0.35
chr17_6325348_6325536 0.24 AIPL1
 aryl hydrocarbon receptor interacting protein-like 1
 12957
 0.19
chrX_101914217_101914428 0.24 RP4-769N13.7
318
 0.86
chr12_66703636_66703787 0.24 HELB
 helicase (DNA) B
 7386
 0.18
chr4_80989302_80989469 0.24 ANTXR2
 anthrax toxin receptor 2
 4332
 0.33
chr15_60822091_60822265 0.24 CTD-2501E16.2
6
 0.98
chr11_64539683_64539961 0.24 SF1
 splicing factor 1
 3279
 0.15
chr1_12230247_12230657 0.24 TNFRSF1B
 tumor necrosis factor receptor superfamily, member 1B
 3392
 0.2
chr8_12965062_12965213 0.24 DLC1
 deleted in liver cancer 1
 8616
 0.24
chr19_47473846_47473997 0.24 ENSG00000252071
 .
 22375
 0.15
chr5_174944747_174945027 0.24 SFXN1
 sideroflexin 1
 39292
 0.16
chr4_1198020_1198171 0.24 SPON2
 spondin 2, extracellular matrix protein
 781
 0.55
chr6_10695659_10695903 0.24 C6orf52
 chromosome 6 open reading frame 52
 751
 0.4
chr12_96782141_96782351 0.23 CDK17
 cyclin-dependent kinase 17
 10896
 0.2
chr18_67557274_67557425 0.23 CD226
 CD226 molecule
 57306
 0.16
chrX_30843390_30843541 0.23 TAB3-AS1
 TAB3 antisense RNA 1
 9275
 0.19
chr6_156721216_156721434 0.23 ENSG00000212295
 .
 21441
 0.29
chr4_99585928_99586079 0.23 RP11-1299A16.3
5948
 0.24
chr11_73717862_73718013 0.23 UCP3
 uncoupling protein 3 (mitochondrial, proton carrier)
 412
 0.81
chr2_204979653_204979829 0.23 ICOS
 inducible T-cell co-stimulator
 178238
 0.03
chr11_82671868_82672034 0.23 PRCP
 prolylcarboxypeptidase (angiotensinase C)
 9675
 0.19
chr3_66665999_66666150 0.23 LRIG1
 leucine-rich repeats and immunoglobulin-like domains 1
 114639
 0.07
chr6_130541447_130541598 0.23 SAMD3
 sterile alpha motif domain containing 3
 2436
 0.4
chr14_33232017_33232168 0.23 AKAP6
 A kinase (PRKA) anchor protein 6
 27035
 0.27
chr17_14115019_14115299 0.23 AC005224.2
1354
 0.46
chr7_106512561_106512750 0.23 PIK3CG
 phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma
 6731
 0.28
chr6_128298731_128298882 0.23 PTPRK
 protein tyrosine phosphatase, receptor type, K
 30416
 0.19
chr12_21829208_21829359 0.23 RP11-59N23.3
14036
 0.18
chr8_29259777_29260051 0.23 RP4-676L2.1
49227
 0.13
chr8_100646172_100646444 0.23 ENSG00000243254
 .
 20002
 0.22
chr14_61909696_61909971 0.23 PRKCH
 protein kinase C, eta
 557
 0.83
chr11_68233574_68233725 0.23 PPP6R3
 protein phosphatase 6, regulatory subunit 3
 5368
 0.2
chr6_44889547_44889698 0.23 SUPT3H
 suppressor of Ty 3 homolog (S. cerevisiae)
 33625
 0.24
chr14_99699047_99699313 0.23 AL109767.1
30105
 0.18
chr17_62138720_62138871 0.23 ICAM2
 intercellular adhesion molecule 2
 40801
 0.11
chr2_176029341_176029492 0.23 ENSG00000215973
 .
 3021
 0.17
chr18_45413878_45414029 0.23 RP11-380M21.4
5138
 0.26
chr15_38979889_38980109 0.23 C15orf53
 chromosome 15 open reading frame 53
 8800
 0.29
chr1_184944092_184944619 0.22 FAM129A
 family with sequence similarity 129, member A
 673
 0.75
chr10_116570599_116570815 0.22 FAM160B1
 family with sequence similarity 160, member B1
 10796
 0.28
chr2_225803106_225803510 0.22 DOCK10
 dedicator of cytokinesis 10
 8474
 0.3
chr20_37462273_37462424 0.22 PPP1R16B
 protein phosphatase 1, regulatory subunit 16B
 27981
 0.15
chr22_40719217_40719484 0.22 ADSL
 adenylosuccinate lyase
 23157
 0.17
chrX_56827923_56828117 0.22 ENSG00000204272
 .
 72328
 0.12
chr10_131967234_131967385 0.22 GLRX3
 glutaredoxin 3
 32646
 0.25
chr16_29712936_29713097 0.22 QPRT
 quinolinate phosphoribosyltransferase
 22513
 0.09
chr13_110936382_110936533 0.22 COL4A2
 collagen, type IV, alpha 2
 21702
 0.2
chr2_230739960_230740111 0.22 TRIP12
 thyroid hormone receptor interactor 12
 16037
 0.16
chr2_171937490_171937641 0.22 TLK1
 tousled-like kinase 1
 14082
 0.25
chr12_1689271_1689422 0.22 WNT5B
 wingless-type MMTV integration site family, member 5B
 5523
 0.23
chrX_122350771_122350922 0.22 GRIA3
 glutamate receptor, ionotropic, AMPA 3
 32081
 0.25
chr1_18980317_18980468 0.22 PAX7
 paired box 7
 22374
 0.26
chr19_42398087_42398358 0.22 ARHGEF1
 Rho guanine nucleotide exchange factor (GEF) 1
 143
 0.93
chr9_134454368_134454603 0.22 RAPGEF1
 Rap guanine nucleotide exchange factor (GEF) 1
 42740
 0.12
chr18_60958641_60958792 0.22 RP11-28F1.2
22599
 0.16
chr1_24839011_24839397 0.22 RCAN3
 RCAN family member 3
 1606
 0.35
chr13_74604155_74604306 0.22 KLF12
 Kruppel-like factor 12
 35044
 0.24
chr20_62489450_62490189 0.22 ABHD16B
 abhydrolase domain containing 16B
 2747
 0.11
chr11_128326646_128326797 0.22 ETS1
 v-ets avian erythroblastosis virus E26 oncogene homolog 1
 48568
 0.17
chr6_112135135_112135400 0.22 FYN
 FYN oncogene related to SRC, FGR, YES
 6014
 0.3
chr6_144976657_144976808 0.22 UTRN
 utrophin
 4248
 0.37
chr8_134574791_134574942 0.22 ST3GAL1
 ST3 beta-galactoside alpha-2,3-sialyltransferase 1
 9226
 0.3
chr15_38854255_38854406 0.22 RASGRP1
 RAS guanyl releasing protein 1 (calcium and DAG-regulated)
 1850
 0.35
chr1_66814646_66814936 0.22 PDE4B
 phosphodiesterase 4B, cAMP-specific
 5274
 0.33
chr3_33058315_33058653 0.22 CCR4
 chemokine (C-C motif) receptor 4
 65418
 0.1
chr17_64362083_64362234 0.22 ENSG00000244044
 .
 2011
 0.37
chr11_33194949_33195100 0.21 ENSG00000206808
 .
 1988
 0.27
chr18_20945112_20945263 0.21 TMEM241
 transmembrane protein 241
 72630
 0.09
chr2_175484770_175484921 0.21 WIPF1
 WAS/WASL interacting protein family, member 1
 14462
 0.2
chr15_68361569_68361757 0.21 PIAS1
 protein inhibitor of activated STAT, 1
 14749
 0.26
chr15_63503410_63503647 0.21 RAB8B
 RAB8B, member RAS oncogene family
 21723
 0.19
chr11_116727307_116727533 0.21 SIK3
 SIK family kinase 3
 7566
 0.11
chr17_70112070_70112221 0.21 SOX9
 SRY (sex determining region Y)-box 9
 5016
 0.33
chr6_24873270_24873525 0.21 FAM65B
 family with sequence similarity 65, member B
 4144
 0.24
chr1_111176210_111176587 0.21 KCNA2
 potassium voltage-gated channel, shaker-related subfamily, member 2
 2302
 0.29
chr9_92061960_92062158 0.21 SEMA4D
 sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D
 8809
 0.25
chr9_114668432_114668747 0.21 UGCG
 UDP-glucose ceramide glucosyltransferase
 9543
 0.2
chr10_127411515_127411666 0.21 EDRF1
 erythroid differentiation regulatory factor 1
 3318
 0.18
chr17_44272799_44272950 0.21 KANSL1-AS1
 KANSL1 antisense RNA 1
 550
 0.67
chr4_129783038_129783517 0.21 JADE1
 jade family PHD finger 1
 30689
 0.24
chr1_6187085_6187236 0.21 CHD5
 chromodomain helicase DNA binding protein 5
 20328
 0.15
chr12_3860944_3861232 0.21 EFCAB4B
 EF-hand calcium binding domain 4B
 1175
 0.56
chr11_96012400_96012646 0.21 ENSG00000266192
 .
 62079
 0.12
chr10_106063927_106064078 0.21 RP11-127L20.5
7897
 0.13
chr21_47309838_47310139 0.21 PCBP3
 poly(rC) binding protein 3
 3803
 0.25
chr8_27935829_27935980 0.21 NUGGC
 nuclear GTPase, germinal center associated
 5463
 0.23
chr3_108551517_108551700 0.21 TRAT1
 T cell receptor associated transmembrane adaptor 1
 9989
 0.26
chr20_47784334_47784563 0.21 STAU1
 staufen double-stranded RNA binding protein 1
 6352
 0.22
chr19_1254241_1254773 0.21 MIDN
 midnolin
 2886
 0.11
chr1_160596062_160596341 0.21 SLAMF1
 signaling lymphocytic activation molecule family member 1
 20610
 0.14
chr11_118743555_118743710 0.21 CXCR5
 chemokine (C-X-C motif) receptor 5
 10843
 0.1
chr1_110041227_110041612 0.21 CYB561D1
 cytochrome b561 family, member D1
 4682
 0.12
chr4_122102125_122102631 0.21 ENSG00000252183
 .
 11680
 0.22
chr5_156778212_156778363 0.21 FNDC9
 fibronectin type III domain containing 9
 5558
 0.17
chr4_109067326_109067500 0.21 LEF1
 lymphoid enhancer-binding factor 1
 20044
 0.21
chr13_114149540_114149691 0.21 TMCO3
 transmembrane and coiled-coil domains 3
 4257
 0.16
chr3_29426463_29426614 0.21 ENSG00000216169
 .
 15626
 0.27
chr1_22407717_22407868 0.21 CDC42-IT1
 CDC42 intronic transcript 1 (non-protein coding)
 22102
 0.13
chr11_122605525_122605776 0.21 ENSG00000239079
 .
 8631
 0.25
chr9_131997515_131997814 0.21 ENSG00000220992
 .
 4668
 0.19
chr17_74265724_74266071 0.21 UBALD2
 UBA-like domain containing 2
 4113
 0.15
chr2_204741991_204742239 0.21 CTLA4
 cytotoxic T-lymphocyte-associated protein 4
 7160
 0.27
chr18_68340696_68340847 0.21 GTSCR1
 Gilles de la Tourette syndrome chromosome region, candidate 1
 22791
 0.28
chr2_28990698_28991000 0.21 PPP1CB
 protein phosphatase 1, catalytic subunit, beta isozyme
 11017
 0.17
chr1_100138406_100138684 0.21 PALMD
 palmdelphin
 26796
 0.21
chr13_40670767_40671082 0.21 ENSG00000207458
 .
 130040
 0.06
chr1_117917956_117918139 0.21 MAN1A2
 mannosidase, alpha, class 1A, member 2
 7976
 0.3

Histogram of CRE-TSS distances for CREs targeted by :

Histogram of

Rank distribution of CRE target scores:

Histogram of target CRE score.

Distribution of target CREs across different genomic regions:

Weighted Piechart of Weighted Piechart of Weighted Piechart of

Network of associatons between targets according to the STRING database.

First level regulatory network of RARB

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.1 GO:0002326 B cell lineage commitment(GO:0002326)
0.1 0.3 GO:0046642 negative regulation of alpha-beta T cell proliferation(GO:0046642)
0.1 0.2 GO:0045589 regulation of regulatory T cell differentiation(GO:0045589)
0.1 0.2 GO:0033152 immunoglobulin V(D)J recombination(GO:0033152)
0.1 0.2 GO:0001831 trophectodermal cellular morphogenesis(GO:0001831)
0.1 0.2 GO:0030223 neutrophil differentiation(GO:0030223)
0.0 0.2 GO:0045091 regulation of single stranded viral RNA replication via double stranded DNA intermediate(GO:0045091)
0.0 0.3 GO:0006198 cAMP catabolic process(GO:0006198)
0.0 0.1 GO:0045722 positive regulation of gluconeogenesis(GO:0045722)
0.0 0.2 GO:0050857 positive regulation of antigen receptor-mediated signaling pathway(GO:0050857)
0.0 0.1 GO:0006007 glucose catabolic process(GO:0006007)
0.0 0.1 GO:0035405 histone-threonine phosphorylation(GO:0035405)
0.0 0.1 GO:0001672 regulation of chromatin assembly or disassembly(GO:0001672)
0.0 0.1 GO:0045066 regulatory T cell differentiation(GO:0045066)
0.0 0.1 GO:0034392 negative regulation of smooth muscle cell apoptotic process(GO:0034392)
0.0 0.1 GO:0048807 female genitalia morphogenesis(GO:0048807)
0.0 0.1 GO:0030854 positive regulation of granulocyte differentiation(GO:0030854)
0.0 0.1 GO:0002677 negative regulation of chronic inflammatory response(GO:0002677)
0.0 0.1 GO:0010592 positive regulation of lamellipodium assembly(GO:0010592) positive regulation of lamellipodium organization(GO:1902745)
0.0 0.1 GO:0010956 negative regulation of calcidiol 1-monooxygenase activity(GO:0010956) negative regulation of vitamin D biosynthetic process(GO:0010957) negative regulation of vitamin metabolic process(GO:0046137)
0.0 0.2 GO:0046827 positive regulation of protein export from nucleus(GO:0046827)
0.0 0.3 GO:0002839 regulation of response to tumor cell(GO:0002834) positive regulation of response to tumor cell(GO:0002836) regulation of immune response to tumor cell(GO:0002837) positive regulation of immune response to tumor cell(GO:0002839)
0.0 0.1 GO:1901339 activation of store-operated calcium channel activity(GO:0032237) regulation of store-operated calcium channel activity(GO:1901339) positive regulation of store-operated calcium channel activity(GO:1901341)
0.0 0.1 GO:0010837 regulation of keratinocyte proliferation(GO:0010837)
0.0 0.1 GO:0032071 regulation of endodeoxyribonuclease activity(GO:0032071)
0.0 0.1 GO:0060737 prostate gland morphogenetic growth(GO:0060737)
0.0 0.3 GO:0043368 positive T cell selection(GO:0043368)
0.0 0.1 GO:0002093 auditory receptor cell morphogenesis(GO:0002093) auditory receptor cell stereocilium organization(GO:0060088)
0.0 0.1 GO:0070266 necroptotic process(GO:0070266) programmed necrotic cell death(GO:0097300)
0.0 0.4 GO:0000303 response to superoxide(GO:0000303)
0.0 0.1 GO:0002313 mature B cell differentiation involved in immune response(GO:0002313)
0.0 0.2 GO:0048934 peripheral nervous system neuron differentiation(GO:0048934)
0.0 0.3 GO:0060325 face morphogenesis(GO:0060325)
0.0 0.0 GO:0071803 regulation of podosome assembly(GO:0071801) positive regulation of podosome assembly(GO:0071803)
0.0 0.1 GO:0043518 negative regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043518) negative regulation of signal transduction by p53 class mediator(GO:1901797)
0.0 0.1 GO:0045906 negative regulation of vasoconstriction(GO:0045906)
0.0 0.0 GO:0019730 antimicrobial humoral response(GO:0019730) antibacterial humoral response(GO:0019731)
0.0 0.3 GO:0045648 positive regulation of erythrocyte differentiation(GO:0045648)
0.0 0.1 GO:0010040 response to iron(II) ion(GO:0010040)
0.0 0.1 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
0.0 0.1 GO:0006290 pyrimidine dimer repair(GO:0006290)
0.0 0.1 GO:0009299 mRNA transcription(GO:0009299)
0.0 0.1 GO:0071569 protein ufmylation(GO:0071569)
0.0 0.1 GO:0034626 fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.0 0.1 GO:0060670 branching involved in labyrinthine layer morphogenesis(GO:0060670)
0.0 0.1 GO:0018343 protein farnesylation(GO:0018343)
0.0 0.1 GO:0046476 glycosylceramide biosynthetic process(GO:0046476)
0.0 0.1 GO:0045634 regulation of melanocyte differentiation(GO:0045634) regulation of pigment cell differentiation(GO:0050932)
0.0 0.0 GO:0021860 pyramidal neuron differentiation(GO:0021859) pyramidal neuron development(GO:0021860)
0.0 0.1 GO:0070933 histone H3 deacetylation(GO:0070932) histone H4 deacetylation(GO:0070933)
0.0 0.2 GO:0006491 N-glycan processing(GO:0006491)
0.0 0.1 GO:0032232 negative regulation of actin filament bundle assembly(GO:0032232)
0.0 0.1 GO:0031946 regulation of glucocorticoid biosynthetic process(GO:0031946)
0.0 0.0 GO:0006772 thiamine metabolic process(GO:0006772)
0.0 0.1 GO:0007132 meiotic metaphase I(GO:0007132)
0.0 0.1 GO:0000491 small nucleolar ribonucleoprotein complex assembly(GO:0000491) box C/D snoRNP assembly(GO:0000492)
0.0 0.1 GO:0033632 regulation of cell-cell adhesion mediated by integrin(GO:0033632)
0.0 0.0 GO:0031935 regulation of chromatin silencing(GO:0031935) negative regulation of chromatin silencing(GO:0031936)
0.0 0.1 GO:0031053 primary miRNA processing(GO:0031053)
0.0 0.1 GO:0032354 response to follicle-stimulating hormone(GO:0032354)
0.0 0.1 GO:0060049 regulation of protein glycosylation(GO:0060049)
0.0 0.0 GO:0046877 regulation of saliva secretion(GO:0046877)
0.0 0.2 GO:0034453 microtubule anchoring(GO:0034453)
0.0 0.2 GO:0046579 positive regulation of Ras protein signal transduction(GO:0046579)
0.0 0.0 GO:0002833 positive regulation of response to biotic stimulus(GO:0002833)
0.0 0.1 GO:0010508 positive regulation of autophagy(GO:0010508)
0.0 0.0 GO:0072161 mesenchymal cell differentiation involved in kidney development(GO:0072161) metanephric mesenchymal cell differentiation(GO:0072162) mesenchymal cell differentiation involved in renal system development(GO:2001012)
0.0 0.0 GO:0060397 JAK-STAT cascade involved in growth hormone signaling pathway(GO:0060397)
0.0 0.1 GO:0010533 regulation of activation of Janus kinase activity(GO:0010533) positive regulation of activation of Janus kinase activity(GO:0010536)
0.0 0.1 GO:0032876 regulation of DNA endoreduplication(GO:0032875) negative regulation of DNA endoreduplication(GO:0032876) DNA endoreduplication(GO:0042023)
0.0 0.1 GO:0042989 sequestering of actin monomers(GO:0042989)
0.0 0.0 GO:0016242 regulation of macroautophagy(GO:0016241) negative regulation of macroautophagy(GO:0016242)
0.0 0.1 GO:0048625 myoblast fate commitment(GO:0048625)
0.0 0.1 GO:0022614 membrane to membrane docking(GO:0022614)
0.0 0.1 GO:0006089 lactate metabolic process(GO:0006089)
0.0 0.0 GO:0006003 fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.0 0.1 GO:0051182 coenzyme transport(GO:0051182)
0.0 0.1 GO:0007195 adenylate cyclase-inhibiting dopamine receptor signaling pathway(GO:0007195)
0.0 0.1 GO:0006924 activation-induced cell death of T cells(GO:0006924)
0.0 0.1 GO:0042510 regulation of tyrosine phosphorylation of Stat1 protein(GO:0042510) positive regulation of tyrosine phosphorylation of Stat1 protein(GO:0042511)
0.0 0.1 GO:0048496 maintenance of organ identity(GO:0048496)
0.0 0.1 GO:0046835 carbohydrate phosphorylation(GO:0046835)
0.0 0.0 GO:0002890 negative regulation of B cell mediated immunity(GO:0002713) negative regulation of immunoglobulin mediated immune response(GO:0002890)
0.0 0.0 GO:0060676 ureteric bud formation(GO:0060676)
0.0 0.1 GO:0090224 regulation of spindle organization(GO:0090224)
0.0 0.1 GO:0042119 neutrophil activation(GO:0042119)
0.0 0.1 GO:0032486 Rap protein signal transduction(GO:0032486)
0.0 0.1 GO:0033235 positive regulation of protein sumoylation(GO:0033235)
0.0 0.0 GO:2001259 positive regulation of calcium ion transmembrane transporter activity(GO:1901021) positive regulation of cation channel activity(GO:2001259)
0.0 0.1 GO:0034139 regulation of toll-like receptor 3 signaling pathway(GO:0034139)
0.0 0.1 GO:0035434 copper ion transmembrane transport(GO:0035434)
0.0 0.1 GO:0018076 N-terminal peptidyl-lysine acetylation(GO:0018076)
0.0 0.0 GO:0042118 endothelial cell activation(GO:0042118)
0.0 0.1 GO:0060677 ureteric bud elongation(GO:0060677)
0.0 0.1 GO:0034629 cellular protein complex localization(GO:0034629)
0.0 0.1 GO:0000019 regulation of mitotic recombination(GO:0000019)
0.0 0.1 GO:0010815 bradykinin catabolic process(GO:0010815)
0.0 0.0 GO:0045112 integrin biosynthetic process(GO:0045112)
0.0 0.1 GO:0010867 positive regulation of triglyceride biosynthetic process(GO:0010867)
0.0 0.1 GO:0070672 response to interleukin-15(GO:0070672)
0.0 0.0 GO:0001766 membrane raft polarization(GO:0001766) membrane raft distribution(GO:0031580)
0.0 0.1 GO:0048312 intracellular distribution of mitochondria(GO:0048312)
0.0 0.0 GO:0060235 lens induction in camera-type eye(GO:0060235)
0.0 0.1 GO:0046607 positive regulation of centrosome cycle(GO:0046607)
0.0 0.1 GO:0090244 Wnt signaling pathway involved in somitogenesis(GO:0090244)
0.0 0.1 GO:0010989 negative regulation of low-density lipoprotein particle clearance(GO:0010989)
0.0 0.0 GO:0048293 isotype switching to IgE isotypes(GO:0048289) regulation of isotype switching to IgE isotypes(GO:0048293)
0.0 0.1 GO:0008535 respiratory chain complex IV assembly(GO:0008535)
0.0 0.1 GO:0032733 positive regulation of interleukin-10 production(GO:0032733)
0.0 0.0 GO:0042362 fat-soluble vitamin biosynthetic process(GO:0042362)
0.0 0.0 GO:0001866 NK T cell proliferation(GO:0001866) NK T cell activation(GO:0051132)
0.0 0.1 GO:0032456 endocytic recycling(GO:0032456)
0.0 0.0 GO:0051934 dopamine uptake involved in synaptic transmission(GO:0051583) catecholamine uptake involved in synaptic transmission(GO:0051934) catecholamine uptake(GO:0090493) dopamine uptake(GO:0090494)
0.0 0.1 GO:0034644 cellular response to UV(GO:0034644)
0.0 0.1 GO:0033631 cell-cell adhesion mediated by integrin(GO:0033631)
0.0 0.4 GO:0050690 regulation of defense response to virus by virus(GO:0050690)
0.0 0.1 GO:0043984 histone H4-K16 acetylation(GO:0043984)
0.0 0.0 GO:0042523 positive regulation of tyrosine phosphorylation of Stat5 protein(GO:0042523)
0.0 0.1 GO:0005981 regulation of glycogen catabolic process(GO:0005981)
0.0 0.0 GO:0034219 carbohydrate transmembrane transport(GO:0034219)
0.0 0.0 GO:0048537 mucosal-associated lymphoid tissue development(GO:0048537)
0.0 0.0 GO:0071354 cellular response to interleukin-6(GO:0071354)
0.0 0.1 GO:0006269 DNA replication, synthesis of RNA primer(GO:0006269)
0.0 0.1 GO:0031954 positive regulation of protein autophosphorylation(GO:0031954)
0.0 0.1 GO:0045793 positive regulation of cell size(GO:0045793)
0.0 0.1 GO:0030206 chondroitin sulfate biosynthetic process(GO:0030206)
0.0 0.0 GO:0070092 regulation of glucagon secretion(GO:0070092)
0.0 0.2 GO:0001954 positive regulation of cell-matrix adhesion(GO:0001954)
0.0 0.1 GO:0015705 iodide transport(GO:0015705)
0.0 0.0 GO:0052555 positive regulation by organism of immune response of other organism involved in symbiotic interaction(GO:0052555) positive regulation by symbiont of host immune response(GO:0052556)
0.0 0.0 GO:0002606 positive regulation of dendritic cell antigen processing and presentation(GO:0002606)
0.0 0.0 GO:0008298 intracellular mRNA localization(GO:0008298)
0.0 0.1 GO:0002707 negative regulation of lymphocyte mediated immunity(GO:0002707)
0.0 0.0 GO:0051531 NFAT protein import into nucleus(GO:0051531) regulation of NFAT protein import into nucleus(GO:0051532)
0.0 0.0 GO:0001574 ganglioside biosynthetic process(GO:0001574)
0.0 0.0 GO:0072216 positive regulation of metanephros development(GO:0072216)
0.0 0.0 GO:0097502 protein mannosylation(GO:0035268) protein O-linked mannosylation(GO:0035269) mannosylation(GO:0097502)
0.0 0.1 GO:0002483 antigen processing and presentation of endogenous peptide antigen(GO:0002483) antigen processing and presentation of endogenous peptide antigen via MHC class I(GO:0019885)
0.0 0.0 GO:0051461 corticotropin secretion(GO:0051458) regulation of corticotropin secretion(GO:0051459) positive regulation of corticotropin secretion(GO:0051461)
0.0 0.0 GO:0001547 antral ovarian follicle growth(GO:0001547)
0.0 0.0 GO:0002282 microglial cell activation involved in immune response(GO:0002282)
0.0 0.0 GO:0070669 response to interleukin-2(GO:0070669)
0.0 0.0 GO:0007100 mitotic centrosome separation(GO:0007100)
0.0 0.1 GO:0051489 regulation of filopodium assembly(GO:0051489)
0.0 0.1 GO:0090286 cytoskeletal anchoring at nuclear membrane(GO:0090286)
0.0 0.1 GO:0000389 mRNA 3'-splice site recognition(GO:0000389)
0.0 0.1 GO:0048535 lymph node development(GO:0048535)
0.0 0.1 GO:0016553 base conversion or substitution editing(GO:0016553)
0.0 0.0 GO:0000733 DNA strand renaturation(GO:0000733)
0.0 0.1 GO:0006600 creatine metabolic process(GO:0006600)
0.0 0.1 GO:0033169 histone H3-K9 demethylation(GO:0033169)
0.0 0.0 GO:0015015 heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.0 0.0 GO:0035066 positive regulation of histone acetylation(GO:0035066) positive regulation of protein acetylation(GO:1901985) positive regulation of peptidyl-lysine acetylation(GO:2000758)
0.0 0.1 GO:0043666 regulation of phosphoprotein phosphatase activity(GO:0043666)
0.0 0.0 GO:0032814 regulation of natural killer cell activation(GO:0032814)
0.0 0.0 GO:0007095 mitotic G2 DNA damage checkpoint(GO:0007095)
0.0 0.0 GO:0032106 positive regulation of response to food(GO:0032097) positive regulation of appetite(GO:0032100) positive regulation of response to extracellular stimulus(GO:0032106) positive regulation of response to nutrient levels(GO:0032109)
0.0 0.0 GO:0030505 inorganic diphosphate transport(GO:0030505)
0.0 0.0 GO:0002063 chondrocyte development(GO:0002063)
0.0 0.0 GO:0032914 positive regulation of transforming growth factor beta1 production(GO:0032914)
0.0 0.1 GO:0030252 growth hormone secretion(GO:0030252)
0.0 0.0 GO:0051798 positive regulation of hair cycle(GO:0042635) positive regulation of hair follicle development(GO:0051798)
0.0 0.0 GO:0006930 substrate-dependent cell migration, cell extension(GO:0006930)
0.0 0.1 GO:0006379 mRNA cleavage(GO:0006379)
0.0 0.1 GO:0019228 neuronal action potential(GO:0019228)
0.0 0.0 GO:0002740 negative regulation of cytokine secretion involved in immune response(GO:0002740)
0.0 0.1 GO:0002920 regulation of humoral immune response(GO:0002920)
0.0 0.0 GO:0032926 negative regulation of activin receptor signaling pathway(GO:0032926)
0.0 0.1 GO:0001578 microtubule bundle formation(GO:0001578)
0.0 0.0 GO:0032776 DNA methylation on cytosine(GO:0032776) C-5 methylation of cytosine(GO:0090116)
0.0 0.0 GO:0022038 corpus callosum development(GO:0022038)
0.0 0.0 GO:0060287 epithelial cilium movement(GO:0003351) epithelial cilium movement involved in determination of left/right asymmetry(GO:0060287)
0.0 0.1 GO:0045003 DNA recombinase assembly(GO:0000730) double-strand break repair via synthesis-dependent strand annealing(GO:0045003)
0.0 0.1 GO:0051085 chaperone mediated protein folding requiring cofactor(GO:0051085)
0.0 0.0 GO:0046541 saliva secretion(GO:0046541)
0.0 0.1 GO:0035303 regulation of dephosphorylation(GO:0035303)
0.0 0.0 GO:0042508 tyrosine phosphorylation of Stat1 protein(GO:0042508)
0.0 0.1 GO:0051016 barbed-end actin filament capping(GO:0051016)
0.0 0.0 GO:0060712 spongiotrophoblast layer development(GO:0060712)
0.0 0.0 GO:0046952 ketone body catabolic process(GO:0046952)
0.0 0.0 GO:0045875 negative regulation of sister chromatid cohesion(GO:0045875)
0.0 0.0 GO:0006498 N-terminal protein lipidation(GO:0006498)
0.0 0.6 GO:0008360 regulation of cell shape(GO:0008360)
0.0 0.1 GO:0051693 actin filament capping(GO:0051693)
0.0 0.0 GO:0033173 calcineurin-NFAT signaling cascade(GO:0033173)
0.0 0.1 GO:0045070 positive regulation of viral genome replication(GO:0045070)
0.0 0.1 GO:0002717 positive regulation of natural killer cell mediated immunity(GO:0002717) positive regulation of natural killer cell mediated cytotoxicity(GO:0045954)
0.0 0.0 GO:0003100 regulation of systemic arterial blood pressure by endothelin(GO:0003100)
0.0 0.2 GO:0016578 histone deubiquitination(GO:0016578)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0030895 apolipoprotein B mRNA editing enzyme complex(GO:0030895)
0.1 0.3 GO:0044224 juxtaparanode region of axon(GO:0044224)
0.0 0.1 GO:0033270 paranode region of axon(GO:0033270)
0.0 0.1 GO:0071438 invadopodium membrane(GO:0071438)
0.0 0.1 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.0 0.1 GO:0005827 polar microtubule(GO:0005827)
0.0 0.1 GO:0043218 compact myelin(GO:0043218)
0.0 0.1 GO:0005797 Golgi medial cisterna(GO:0005797)
0.0 0.1 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.0 0.1 GO:0005900 oncostatin-M receptor complex(GO:0005900)
0.0 0.1 GO:0098647 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.0 0.1 GO:0072487 MSL complex(GO:0072487)
0.0 0.1 GO:0030934 anchoring collagen complex(GO:0030934)
0.0 0.1 GO:0034673 inhibin-betaglycan-ActRII complex(GO:0034673)
0.0 0.1 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)
0.0 0.1 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.0 0.2 GO:0001891 phagocytic cup(GO:0001891)
0.0 0.1 GO:0032591 dendritic spine membrane(GO:0032591)
0.0 0.1 GO:0005828 kinetochore microtubule(GO:0005828)
0.0 0.1 GO:0032444 activin responsive factor complex(GO:0032444)
0.0 0.1 GO:0030121 AP-1 adaptor complex(GO:0030121)
0.0 0.1 GO:0002142 stereocilia coupling link(GO:0002139) stereocilia ankle link(GO:0002141) stereocilia ankle link complex(GO:0002142)
0.0 0.1 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
0.0 0.1 GO:0034464 BBSome(GO:0034464)
0.0 0.1 GO:1990316 ATG1/ULK1 kinase complex(GO:1990316)
0.0 0.1 GO:0000124 SAGA complex(GO:0000124)
0.0 0.1 GO:0033256 I-kappaB/NF-kappaB complex(GO:0033256)
0.0 0.1 GO:0005847 mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.0 0.1 GO:0005826 actomyosin contractile ring(GO:0005826)
0.0 0.1 GO:0034451 centriolar satellite(GO:0034451)
0.0 0.1 GO:0042101 T cell receptor complex(GO:0042101)
0.0 0.1 GO:0030056 hemidesmosome(GO:0030056)
0.0 0.0 GO:0005896 interleukin-6 receptor complex(GO:0005896)
0.0 0.1 GO:0005587 collagen type IV trimer(GO:0005587)
0.0 0.2 GO:0031105 septin complex(GO:0031105) septin cytoskeleton(GO:0032156)
0.0 0.0 GO:0000306 extrinsic component of vacuolar membrane(GO:0000306) extrinsic component of endosome membrane(GO:0031313)
0.0 0.0 GO:0031501 mannosyltransferase complex(GO:0031501) dolichol-phosphate-mannose synthase complex(GO:0033185)
0.0 0.0 GO:0033150 cytoskeletal calyx(GO:0033150)
0.0 0.1 GO:0034992 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.0 0.1 GO:0042598 obsolete vesicular fraction(GO:0042598)
0.0 0.2 GO:0071203 WASH complex(GO:0071203)
0.0 0.1 GO:0016942 insulin-like growth factor binding protein complex(GO:0016942) growth factor complex(GO:0036454)
0.0 0.1 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.0 0.0 GO:0071437 invadopodium(GO:0071437)
0.0 0.0 GO:0097526 U4/U6 x U5 tri-snRNP complex(GO:0046540) spliceosomal tri-snRNP complex(GO:0097526)
0.0 0.1 GO:0043209 myelin sheath(GO:0043209)
0.0 0.0 GO:0098645 network-forming collagen trimer(GO:0098642) collagen network(GO:0098645)
0.0 0.4 GO:0030175 filopodium(GO:0030175)
0.0 0.0 GO:0001740 Barr body(GO:0001740)
0.0 0.1 GO:0070761 pre-snoRNP complex(GO:0070761)
0.0 0.0 GO:0016939 kinesin II complex(GO:0016939)
0.0 0.1 GO:0043190 ATP-binding cassette (ABC) transporter complex(GO:0043190)
0.0 0.1 GO:0070776 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.0 0.1 GO:0000242 pericentriolar material(GO:0000242)
0.0 0.0 GO:0005686 U2 snRNP(GO:0005686)
0.0 0.0 GO:0031931 TORC1 complex(GO:0031931)
0.0 0.0 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0035184 histone threonine kinase activity(GO:0035184)
0.0 0.0 GO:0019959 C-X-C chemokine binding(GO:0019958) interleukin-8 binding(GO:0019959)
0.0 0.1 GO:0016309 1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
0.0 0.5 GO:0004697 protein kinase C activity(GO:0004697)
0.0 0.1 GO:0003836 beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.0 0.2 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.0 0.1 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454)
0.0 0.1 GO:0003986 acetyl-CoA hydrolase activity(GO:0003986)
0.0 0.1 GO:0043125 ErbB-3 class receptor binding(GO:0043125)
0.0 0.1 GO:0004111 creatine kinase activity(GO:0004111)
0.0 0.1 GO:0031127 galactoside 2-alpha-L-fucosyltransferase activity(GO:0008107) alpha-(1,2)-fucosyltransferase activity(GO:0031127)
0.0 0.2 GO:0016494 C-X-C chemokine receptor activity(GO:0016494)
0.0 0.1 GO:0050321 tau-protein kinase activity(GO:0050321)
0.0 0.1 GO:0004949 cannabinoid receptor activity(GO:0004949)
0.0 0.2 GO:0004126 cytidine deaminase activity(GO:0004126)
0.0 0.1 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.0 0.1 GO:0004311 farnesyltranstransferase activity(GO:0004311)
0.0 0.1 GO:0004911 interleukin-2 receptor activity(GO:0004911)
0.0 0.2 GO:0030332 cyclin binding(GO:0030332)
0.0 0.1 GO:0004897 ciliary neurotrophic factor receptor activity(GO:0004897)
0.0 0.1 GO:0052813 phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) phosphatidylinositol bisphosphate kinase activity(GO:0052813)
0.0 0.2 GO:0070087 chromo shadow domain binding(GO:0070087)
0.0 0.1 GO:0030284 estrogen receptor activity(GO:0030284)
0.0 0.1 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.0 0.1 GO:0004946 bombesin receptor activity(GO:0004946)
0.0 0.1 GO:0004924 oncostatin-M receptor activity(GO:0004924)
0.0 0.1 GO:0043141 ATP-dependent 5'-3' DNA helicase activity(GO:0043141)
0.0 0.1 GO:0005087 Ran guanyl-nucleotide exchange factor activity(GO:0005087)
0.0 0.1 GO:0016312 inositol bisphosphate phosphatase activity(GO:0016312)
0.0 0.1 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.0 0.1 GO:0030235 nitric-oxide synthase regulator activity(GO:0030235)
0.0 0.2 GO:0015271 outward rectifier potassium channel activity(GO:0015271)
0.0 0.1 GO:0003726 double-stranded RNA adenosine deaminase activity(GO:0003726)
0.0 0.1 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
0.0 0.2 GO:0016493 C-C chemokine receptor activity(GO:0016493)
0.0 0.1 GO:0030020 extracellular matrix structural constituent conferring tensile strength(GO:0030020)
0.0 0.1 GO:0001784 phosphotyrosine binding(GO:0001784)
0.0 0.1 GO:0015204 urea transmembrane transporter activity(GO:0015204)
0.0 0.1 GO:0004351 glutamate decarboxylase activity(GO:0004351)
0.0 0.1 GO:0015925 galactosidase activity(GO:0015925)
0.0 0.1 GO:0005522 profilin binding(GO:0005522)
0.0 0.1 GO:0030618 transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity(GO:0030618)
0.0 0.1 GO:0042808 obsolete neuronal Cdc2-like kinase binding(GO:0042808)
0.0 0.2 GO:0005283 sodium:amino acid symporter activity(GO:0005283)
0.0 0.1 GO:0005315 inorganic phosphate transmembrane transporter activity(GO:0005315)
0.0 0.1 GO:1990939 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574) ATP-dependent microtubule motor activity(GO:1990939)
0.0 0.1 GO:0043274 phospholipase binding(GO:0043274)
0.0 0.1 GO:0031013 troponin I binding(GO:0031013)
0.0 0.1 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.0 0.1 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.0 0.1 GO:0016842 amidine-lyase activity(GO:0016842)
0.0 0.1 GO:0034481 chondroitin sulfotransferase activity(GO:0034481)
0.0 0.0 GO:0001098 basal transcription machinery binding(GO:0001098) basal RNA polymerase II transcription machinery binding(GO:0001099)
0.0 0.1 GO:0004300 enoyl-CoA hydratase activity(GO:0004300)
0.0 0.1 GO:0016417 S-acyltransferase activity(GO:0016417)
0.0 0.3 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0 0.1 GO:0034593 phosphatidylinositol bisphosphate phosphatase activity(GO:0034593)
0.0 0.1 GO:0005114 type II transforming growth factor beta receptor binding(GO:0005114)
0.0 0.0 GO:0004802 transketolase activity(GO:0004802)
0.0 0.0 GO:0050265 RNA uridylyltransferase activity(GO:0050265)
0.0 0.0 GO:0098518 polynucleotide phosphatase activity(GO:0098518)
0.0 0.1 GO:0004706 JUN kinase kinase kinase activity(GO:0004706)
0.0 0.1 GO:0001637 G-protein coupled chemoattractant receptor activity(GO:0001637) chemokine receptor activity(GO:0004950)
0.0 0.1 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.0 0.1 GO:0008195 phosphatidate phosphatase activity(GO:0008195)
0.0 0.0 GO:0070653 high-density lipoprotein particle receptor binding(GO:0070653)
0.0 0.1 GO:0004459 L-lactate dehydrogenase activity(GO:0004459)
0.0 0.1 GO:0015252 hydrogen ion channel activity(GO:0015252)
0.0 0.0 GO:0042156 obsolete zinc-mediated transcriptional activator activity(GO:0042156)
0.0 0.1 GO:0043495 protein anchor(GO:0043495)
0.0 0.0 GO:0004582 dolichyl-phosphate beta-D-mannosyltransferase activity(GO:0004582)
0.0 0.1 GO:0051010 microtubule plus-end binding(GO:0051010)
0.0 0.0 GO:0030911 TPR domain binding(GO:0030911)
0.0 0.1 GO:0005072 transforming growth factor beta receptor, cytoplasmic mediator activity(GO:0005072)
0.0 0.2 GO:0042162 telomeric DNA binding(GO:0042162)
0.0 0.1 GO:0051879 Hsp90 protein binding(GO:0051879)
0.0 0.1 GO:0051018 protein kinase A binding(GO:0051018)
0.0 0.1 GO:0031545 procollagen-proline 4-dioxygenase activity(GO:0004656) peptidyl-proline 4-dioxygenase activity(GO:0031545)
0.0 0.0 GO:0030899 calcium-dependent ATPase activity(GO:0030899)
0.0 0.0 GO:0047499 calcium-independent phospholipase A2 activity(GO:0047499)
0.0 0.0 GO:0035252 UDP-xylosyltransferase activity(GO:0035252) xylosyltransferase activity(GO:0042285)
0.0 0.0 GO:0035197 siRNA binding(GO:0035197)
0.0 0.0 GO:0016715 dopamine beta-monooxygenase activity(GO:0004500) oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen(GO:0016715)
0.0 0.1 GO:0005375 copper ion transmembrane transporter activity(GO:0005375)
0.0 0.0 GO:0008109 N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109)
0.0 0.1 GO:0016944 obsolete RNA polymerase II transcription elongation factor activity(GO:0016944)
0.0 0.0 GO:0010485 H4 histone acetyltransferase activity(GO:0010485)
0.0 0.0 GO:0004514 nicotinate-nucleotide diphosphorylase (carboxylating) activity(GO:0004514)
0.0 0.2 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.0 0.2 GO:0019198 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.0 0.1 GO:0016778 diphosphotransferase activity(GO:0016778)
0.0 0.1 GO:0031432 titin binding(GO:0031432)
0.0 0.0 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.0 0.1 GO:0004952 dopamine neurotransmitter receptor activity(GO:0004952)
0.0 0.0 GO:0043008 ATP-dependent protein binding(GO:0043008)
0.0 0.1 GO:0005031 tumor necrosis factor-activated receptor activity(GO:0005031)
0.0 0.1 GO:0016670 oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor(GO:0016670)
0.0 0.1 GO:0043138 3'-5' DNA helicase activity(GO:0043138)
0.0 0.0 GO:0003910 DNA ligase activity(GO:0003909) DNA ligase (ATP) activity(GO:0003910)
0.0 0.1 GO:0050700 CARD domain binding(GO:0050700)
0.0 0.1 GO:0070513 death domain binding(GO:0070513)
0.0 0.2 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.0 0.0 GO:0034452 dynactin binding(GO:0034452)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.9 PID CD8 TCR PATHWAY TCR signaling in naïve CD8+ T cells
0.0 0.0 ST GRANULE CELL SURVIVAL PATHWAY Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway.
0.0 0.4 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0 0.2 SA FAS SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.0 0.2 PID BCR 5PATHWAY BCR signaling pathway
0.0 0.0 PID EPHRINB REV PATHWAY Ephrin B reverse signaling
0.0 0.7 PID TXA2PATHWAY Thromboxane A2 receptor signaling
0.0 0.3 PID RAC1 REG PATHWAY Regulation of RAC1 activity
0.0 0.0 PID TCR RAS PATHWAY Ras signaling in the CD4+ TCR pathway
0.0 0.5 PID ERBB1 INTERNALIZATION PATHWAY Internalization of ErbB1
0.0 0.1 ST JAK STAT PATHWAY Jak-STAT Pathway
0.0 0.2 PID IL2 PI3K PATHWAY IL2 signaling events mediated by PI3K
0.0 0.8 PID IL4 2PATHWAY IL4-mediated signaling events
0.0 0.0 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.0 0.4 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.0 0.0 ST DIFFERENTIATION PATHWAY IN PC12 CELLS Differentiation Pathway in PC12 Cells; this is a specific case of PAC1 Receptor Pathway.
0.0 0.3 PID FCER1 PATHWAY Fc-epsilon receptor I signaling in mast cells
0.0 0.1 PID LYMPH ANGIOGENESIS PATHWAY VEGFR3 signaling in lymphatic endothelium
0.0 0.1 ST INTERFERON GAMMA PATHWAY Interferon gamma pathway.
0.0 0.1 PID P38 ALPHA BETA PATHWAY Regulation of p38-alpha and p38-beta
0.0 0.1 PID PI3K PLC TRK PATHWAY Trk receptor signaling mediated by PI3K and PLC-gamma
0.0 0.2 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.1 REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE Genes involved in Translocation of ZAP-70 to Immunological synapse
0.1 0.5 REACTOME PECAM1 INTERACTIONS Genes involved in PECAM1 interactions
0.0 0.0 REACTOME CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
0.0 0.0 REACTOME HIV INFECTION Genes involved in HIV Infection
0.0 0.1 REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
0.0 0.2 REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.0 0.7 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.0 0.1 REACTOME BINDING AND ENTRY OF HIV VIRION Genes involved in Binding and entry of HIV virion
0.0 0.0 REACTOME DOWNSTREAM SIGNALING EVENTS OF B CELL RECEPTOR BCR Genes involved in Downstream Signaling Events Of B Cell Receptor (BCR)
0.0 0.3 REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.0 0.1 REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX UPON TLR7 8 OR 9 STIMULATION Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
0.0 0.4 REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.0 0.2 REACTOME GENERATION OF SECOND MESSENGER MOLECULES Genes involved in Generation of second messenger molecules
0.0 0.2 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.0 0.2 REACTOME GPVI MEDIATED ACTIVATION CASCADE Genes involved in GPVI-mediated activation cascade
0.0 0.3 REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.0 0.0 REACTOME P53 DEPENDENT G1 DNA DAMAGE RESPONSE Genes involved in p53-Dependent G1 DNA Damage Response
0.0 0.1 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.0 0.2 REACTOME ALPHA LINOLENIC ACID ALA METABOLISM Genes involved in alpha-linolenic acid (ALA) metabolism
0.0 0.1 REACTOME UNBLOCKING OF NMDA RECEPTOR GLUTAMATE BINDING AND ACTIVATION Genes involved in Unblocking of NMDA receptor, glutamate binding and activation
0.0 0.1 REACTOME REGULATION OF SIGNALING BY CBL Genes involved in Regulation of signaling by CBL
0.0 0.1 REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.0 0.2 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.0 0.2 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.0 0.3 REACTOME SEMA4D IN SEMAPHORIN SIGNALING Genes involved in Sema4D in semaphorin signaling
0.0 0.0 REACTOME SOS MEDIATED SIGNALLING Genes involved in SOS-mediated signalling
0.0 0.0 REACTOME APC C CDC20 MEDIATED DEGRADATION OF MITOTIC PROTEINS Genes involved in APC/C:Cdc20 mediated degradation of mitotic proteins
0.0 0.1 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.0 0.0 REACTOME SCF BETA TRCP MEDIATED DEGRADATION OF EMI1 Genes involved in SCF-beta-TrCP mediated degradation of Emi1
0.0 0.1 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.0 0.2 REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.0 0.2 REACTOME PRE NOTCH TRANSCRIPTION AND TRANSLATION Genes involved in Pre-NOTCH Transcription and Translation
0.0 0.4 REACTOME COSTIMULATION BY THE CD28 FAMILY Genes involved in Costimulation by the CD28 family