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ENCODE: H3K4me1 ChIP-Seq of primary human cells
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Results for RBPJ

Z-value: 0.44

Motif logo

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Transcription factors associated with RBPJ

Gene Symbol Gene ID Gene Info
RBPJ
ENSG00000168214.16 recombination signal binding protein for immunoglobulin kappa J region

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE Gene Distance Association probability Pearson corr. coef. P-value Plot
chr4_26454784_26454935RBPJ245170.2156970.917.4e-04Click!
chr4_26198232_26198383RBPJ332300.242958-0.801.0e-02Click!
chr4_26459444_26459886RBPJ293230.1979820.801.0e-02Click!
chr4_26387680_26387953RBPJ236640.257737-0.771.5e-02Click!
chr4_26300891_26301042RBPJ203180.282335-0.752.0e-02Click!

Activity of the RBPJ motif across conditions

Conditions sorted by the z-value of the RBPJ motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE) Target Score Top associated gene Gene Info Distance of CRE to TSS CRE/Gene association probability
chr7_140542463_140542763 0.09 ENSG00000271932
 .
 41259
 0.15
chr3_112115394_112115545 0.08 CD200
 CD200 molecule
 63444
 0.12
chr3_71585804_71586230 0.08 ENSG00000221264
 .
 5223
 0.23
chr2_66706378_66706529 0.08 MEIS1
 Meis homeobox 1
 29606
 0.16
chr4_55684754_55684905 0.08 KIT
 v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
 160744
 0.04
chr2_46067140_46067427 0.08 PRKCE
 protein kinase C, epsilon
 160758
 0.04
chr5_149524173_149524324 0.07 PDGFRB
 platelet-derived growth factor receptor, beta polypeptide
 7248
 0.15
chr3_184503248_184503626 0.07 VPS8
 vacuolar protein sorting 8 homolog (S. cerevisiae)
 26494
 0.22
chr9_127520364_127520515 0.07 RP11-175D17.3
11963
 0.14
chr2_20795415_20795848 0.07 HS1BP3-IT1
 HS1BP3 intronic transcript 1 (non-protein coding)
 3323
 0.28
chr18_7116494_7116699 0.07 LAMA1
 laminin, alpha 1
 1217
 0.55
chr15_65010591_65010969 0.07 OAZ2
 ornithine decarboxylase antizyme 2
 15300
 0.11
chr21_46677673_46677824 0.06 POFUT2
 protein O-fucosyltransferase 2
 27858
 0.16
chr12_5310016_5310167 0.06 KCNA5
 potassium voltage-gated channel, shaker-related subfamily, member 5
 157006
 0.04
chr2_68499522_68499673 0.06 ENSG00000221443
 .
 639
 0.65
chr15_89565634_89565983 0.06 ENSG00000265866
 .
 50125
 0.12
chr19_41857694_41857871 0.06 TMEM91
 transmembrane protein 91
 966
 0.33
chr5_10401090_10401251 0.06 MARCH6
 membrane-associated ring finger (C3HC4) 6, E3 ubiquitin protein ligase
 799
 0.58
chr8_20400144_20400295 0.06 ENSG00000251944
 .
 72218
 0.13
chr13_44999768_45000008 0.06 TSC22D1
 TSC22 domain family, member 1
 11093
 0.27
chr6_7202982_7203133 0.06 ENSG00000201483
 .
 15138
 0.18
chr10_82181954_82182105 0.06 FAM213A
 family with sequence similarity 213, member A
 2275
 0.31
chr15_89973751_89973944 0.06 RHCG
 Rh family, C glycoprotein
 48814
 0.11
chr12_70222735_70222886 0.06 MYRFL
 myelin regulatory factor-like
 3714
 0.27
chr3_169028756_169028966 0.06 MECOM
 MDS1 and EVI1 complex locus
 41835
 0.2
chr22_45095245_45095396 0.05 PRR5
 proline rich 5 (renal)
 2758
 0.23
chr4_118904844_118905063 0.05 NDST3
 N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 3
 50547
 0.19
chr1_61870079_61870321 0.05 NFIA
 nuclear factor I/A
 452
 0.9
chr1_160681135_160681490 0.05 CD48
 CD48 molecule
 281
 0.89
chr16_85596439_85597190 0.05 GSE1
 Gse1 coiled-coil protein
 48201
 0.14
chr11_9182138_9182467 0.05 DENND5A
 DENN/MADD domain containing 5A
 8348
 0.2
chr1_226234793_226235057 0.05 H3F3A
 H3 histone, family 3A
 14627
 0.16
chr3_64672491_64672773 0.05 ADAMTS9
 ADAM metallopeptidase with thrombospondin type 1 motif, 9
 723
 0.66
chr8_67344451_67344602 0.05 ADHFE1
 alcohol dehydrogenase, iron containing, 1
 192
 0.94
chr1_159870702_159871247 0.05 CCDC19
 coiled-coil domain containing 19
 1021
 0.28
chr12_94503240_94503391 0.05 PLXNC1
 plexin C1
 39184
 0.17
chr1_207244763_207244987 0.05 PFKFB2
 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2
 6526
 0.14
chr2_74277135_74277286 0.05 TET3
 tet methylcytosine dioxygenase 3
 3760
 0.22
chr1_64091668_64091877 0.05 PGM1
 phosphoglucomutase 1
 3008
 0.26
chr5_159107_159571 0.05 ENSG00000199540
 .
 15027
 0.14
chr5_75671808_75671959 0.05 IQGAP2
 IQ motif containing GTPase activating protein 2
 27191
 0.22
chr12_122418604_122418840 0.05 BCL7A
 B-cell CLL/lymphoma 7A
 38606
 0.14
chr2_129396287_129396587 0.05 ENSG00000238379
 .
 193665
 0.03
chr3_52534556_52534707 0.05 STAB1
 stabilin 1
 5277
 0.12
chr3_120154150_120154396 0.05 FSTL1
 follistatin-like 1
 15565
 0.24
chr1_224518195_224518346 0.05 NVL
 nuclear VCP-like
 181
 0.93
chr19_51642798_51642949 0.05 SIGLEC7
 sialic acid binding Ig-like lectin 7
 2683
 0.13
chr9_8718709_8718860 0.05 PTPRD
 protein tyrosine phosphatase, receptor type, D
 15110
 0.22
chr3_151066989_151067140 0.05 P2RY13
 purinergic receptor P2Y, G-protein coupled, 13
 19728
 0.16
chr10_114612004_114612375 0.05 RP11-57H14.4
28940
 0.19
chr1_230294761_230294912 0.05 GALNT2
 UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 2 (GalNAc-T2)
 91818
 0.08
chr11_303734_303885 0.05 IFITM2
 interferon induced transmembrane protein 2
 3822
 0.08
chr13_27556748_27557003 0.05 USP12-AS1
 USP12 antisense RNA 1
 180117
 0.03
chr18_24294487_24294638 0.05 ENSG00000265369
 .
 25069
 0.2
chr13_51905768_51905919 0.05 SERPINE3
 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 3
 4066
 0.18
chr7_2775422_2775573 0.05 GNA12
 guanine nucleotide binding protein (G protein) alpha 12
 27277
 0.18
chr15_82232869_82233020 0.05 ENSG00000222521
 .
 103691
 0.07
chr7_102552878_102553029 0.05 LRRC17
 leucine rich repeat containing 17
 485
 0.81
chr3_16127076_16127227 0.05 GALNT15
 UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 15
 89005
 0.09
chr2_109275037_109275317 0.05 LIMS1
 LIM and senescent cell antigen-like domains 1
 3668
 0.26
chr12_109248280_109248431 0.05 SSH1
 slingshot protein phosphatase 1
 3004
 0.2
chr2_29769435_29769586 0.05 ENSG00000266310
 .
 42651
 0.2
chr13_32691092_32691282 0.05 FRY
 furry homolog (Drosophila)
 56186
 0.14
chr9_129094506_129094657 0.05 MVB12B
 multivesicular body subunit 12B
 2917
 0.35
chr20_40138790_40139006 0.04 CHD6
 chromodomain helicase DNA binding protein 6
 10941
 0.28
chr2_60640689_60640976 0.04 ENSG00000266078
 .
 26252
 0.19
chr12_106695790_106695941 0.04 TCP11L2
 t-complex 11, testis-specific-like 2
 158
 0.94
chrX_30671018_30671169 0.04 GK
 glycerol kinase
 383
 0.86
chr3_193857613_193857764 0.04 HES1
 hes family bHLH transcription factor 1
 3754
 0.23
chr3_138581340_138581807 0.04 PIK3CB
 phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta
 27793
 0.2
chr3_186790709_186790860 0.04 ST6GAL1
 ST6 beta-galactosamide alpha-2,6-sialyltranferase 1
 29253
 0.19
chr22_23933989_23934140 0.04 IGLL1
 immunoglobulin lambda-like polypeptide 1
 11569
 0.15
chr12_107486536_107486701 0.04 RP11-797M17.1
458
 0.71
chr19_52006625_52006805 0.04 SIGLEC12
 sialic acid binding Ig-like lectin 12 (gene/pseudogene)
 1672
 0.22
chr10_35640492_35640744 0.04 CCNY
 cyclin Y
 14816
 0.2
chr5_81144030_81144509 0.04 SSBP2
 single-stranded DNA binding protein 2
 97197
 0.08
chr15_57441064_57441218 0.04 TCF12
 transcription factor 12
 70487
 0.12
chr4_57980142_57980293 0.04 IGFBP7
 insulin-like growth factor binding protein 7
 3666
 0.21
chr6_43968341_43968530 0.04 C6orf223
 chromosome 6 open reading frame 223
 81
 0.97
chr13_108102387_108102666 0.04 ENSG00000221650
 .
 81070
 0.11
chr8_61245272_61245534 0.04 CA8
 carbonic anhydrase VIII
 51432
 0.18
chr8_62672510_62672919 0.04 ENSG00000264408
 .
 45367
 0.17
chr3_119265682_119265833 0.04 CD80
 CD80 molecule
 10818
 0.15
chr9_125810997_125811288 0.04 GPR21
 G protein-coupled receptor 21
 14336
 0.17
chr2_124782496_124782647 0.04 AC079154.1
179
 0.65
chr11_62165677_62166025 0.04 CTD-2531D15.5
5007
 0.13
chr18_10059619_10060204 0.04 ENSG00000263630
 .
 54717
 0.15
chr1_183573322_183573539 0.04 NCF2
 neutrophil cytosolic factor 2
 13419
 0.17
chr4_11100801_11100971 0.04 ENSG00000207716
 .
 269565
 0.02
chr5_172266910_172267216 0.04 ERGIC1
 endoplasmic reticulum-golgi intermediate compartment (ERGIC) 1
 5649
 0.2
chr17_40109541_40109731 0.04 CNP
 2',3'-cyclic nucleotide 3' phosphodiesterase
 9123
 0.12
chr2_37016528_37016679 0.04 VIT
 vitrin
 15648
 0.22
chr3_46263444_46263746 0.04 CCR1
 chemokine (C-C motif) receptor 1
 13708
 0.2
chr3_133710084_133710385 0.04 SLCO2A1
 solute carrier organic anion transporter family, member 2A1
 38524
 0.17
chr9_7081128_7081335 0.04 KDM4C
 lysine (K)-specific demethylase 4C
 67443
 0.14
chr10_72500668_72500819 0.04 TBATA
 thymus, brain and testes associated
 41645
 0.15
chr5_160145_160296 0.04 ENSG00000199540
 .
 15908
 0.14
chr1_246349977_246350128 0.04 ENSG00000202184
 .
 2368
 0.32
chr8_108510907_108511284 0.04 ANGPT1
 angiopoietin 1
 812
 0.78
chr4_8274597_8274776 0.04 HTRA3
 HtrA serine peptidase 3
 3182
 0.29
chr14_85786368_85786640 0.04 ENSG00000252529
 .
 48228
 0.2
chr1_201501281_201501432 0.04 CSRP1
 cysteine and glycine-rich protein 1
 22772
 0.15
chr20_33291227_33291378 0.04 TP53INP2
 tumor protein p53 inducible nuclear protein 2
 792
 0.67
chr11_9731889_9732040 0.04 SWAP70
 SWAP switching B-cell complex 70kDa subunit
 9649
 0.18
chr1_223351560_223351778 0.04 TLR5
 toll-like receptor 5
 35045
 0.22
chr17_45020470_45020621 0.04 GOSR2
 golgi SNAP receptor complex member 2
 4580
 0.17
chr4_176922781_176923153 0.04 GPM6A
 glycoprotein M6A
 516
 0.83
chr2_8678901_8679157 0.04 AC011747.7
136867
 0.05
chr2_122465053_122465293 0.04 ENSG00000238341
 .
 1540
 0.37
chr6_21832322_21832575 0.04 SOX4
 SRY (sex determining region Y)-box 4
 238377
 0.02
chr2_48475922_48476221 0.04 ENSG00000201010
 .
 31357
 0.2
chr6_34865245_34865499 0.04 ANKS1A
 ankyrin repeat and sterile alpha motif domain containing 1A
 8292
 0.2
chr1_111098007_111098158 0.04 KCNA10
 potassium voltage-gated channel, shaker-related subfamily, member 10
 36285
 0.13
chr1_10125719_10125870 0.04 UBE4B
 ubiquitination factor E4B
 32140
 0.14
chr2_152191078_152191290 0.04 TNFAIP6
 tumor necrosis factor, alpha-induced protein 6
 22922
 0.15
chr3_124378361_124378512 0.04 KALRN
 kalirin, RhoGEF kinase
 17751
 0.18
chr15_79615080_79615231 0.04 TMED3
 transmembrane emp24 protein transport domain containing 3
 11657
 0.19
chr2_74994703_74994854 0.04 HK2
 hexokinase 2
 66330
 0.1
chr9_133769634_133769785 0.04 QRFP
 pyroglutamylated RFamide peptide
 484
 0.8
chr1_192139874_192140185 0.04 RGS18
 regulator of G-protein signaling 18
 12442
 0.31
chr3_194973552_194973874 0.04 XXYLT1
 xyloside xylosyltransferase 1
 5064
 0.19
chr2_220325041_220325196 0.04 SPEG
 SPEG complex locus
 370
 0.75
chr12_3861332_3861486 0.04 EFCAB4B
 EF-hand calcium binding domain 4B
 854
 0.68
chr1_150337439_150337590 0.04 RPRD2
 regulation of nuclear pre-mRNA domain containing 2
 327
 0.86
chr18_12596233_12596512 0.04 SPIRE1
 spire-type actin nucleation factor 1
 56712
 0.09
chr12_96388567_96388718 0.04 HAL
 histidine ammonia-lyase
 336
 0.81
chr9_80997377_80997562 0.04 PSAT1
 phosphoserine aminotransferase 1
 85410
 0.1
chr17_76238005_76238295 0.04 TMEM235
 transmembrane protein 235
 10028
 0.13
chr21_46530039_46530452 0.04 PRED58
4628
 0.17
chr8_37773430_37773841 0.04 ENSG00000241032
 .
 7376
 0.14
chr1_199151279_199151430 0.04 ENSG00000239006
 .
 14958
 0.31
chr11_19221194_19221345 0.04 CSRP3
 cysteine and glycine-rich protein 3 (cardiac LIM protein)
 2320
 0.27
chr22_30753251_30753448 0.04 CCDC157
 coiled-coil domain containing 157
 353
 0.48
chr1_66859382_66859614 0.04 PDE4B
 phosphodiesterase 4B, cAMP-specific
 39433
 0.21
chr1_221271721_221272131 0.04 HLX
 H2.0-like homeobox
 217342
 0.02
chr12_76937660_76937890 0.04 OSBPL8
 oxysterol binding protein-like 8
 15509
 0.29
chr16_72870979_72871130 0.04 ENSG00000251868
 .
 15163
 0.18
chr12_124252156_124252428 0.04 DNAH10
 dynein, axonemal, heavy chain 10
 5250
 0.19
chr1_201526153_201526357 0.04 CSRP1
 cysteine and glycine-rich protein 1
 47671
 0.1
chr12_4000260_4000425 0.04 RP11-664D1.1
7877
 0.24
chr5_122227048_122227199 0.04 SNX24
 sorting nexin 24
 45802
 0.13
chr18_74333332_74333853 0.04 LINC00908
 long intergenic non-protein coding RNA 908
 92718
 0.08
chr13_107571963_107572200 0.04 ENSG00000239050
 .
 55293
 0.17
chr1_229165049_229165220 0.04 RP5-1061H20.5
198175
 0.02
chr1_90377108_90377305 0.04 LRRC8D
 leucine rich repeat containing 8 family, member D
 65067
 0.11
chr3_190252277_190252428 0.03 IL1RAP
 interleukin 1 receptor accessory protein
 20461
 0.24
chr6_89855370_89855671 0.03 PM20D2
 peptidase M20 domain containing 2
 249
 0.91
chr6_86388179_86388330 0.03 ENSG00000203875
 .
 878
 0.62
chr11_131928609_131928889 0.03 RP11-697E14.2
74194
 0.12
chr20_2260711_2261046 0.03 TGM3
 transglutaminase 3
 15769
 0.23
chr3_179182596_179182747 0.03 GNB4
 guanine nucleotide binding protein (G protein), beta polypeptide 4
 13293
 0.18
chr9_140162312_140162640 0.03 TOR4A
 torsin family 4, member A
 9725
 0.07
chr1_201523227_201523378 0.03 CSRP1
 cysteine and glycine-rich protein 1
 44718
 0.11
chr18_47813563_47813872 0.03 CXXC1
 CXXC finger protein 1
 223
 0.92
chr12_20557465_20557616 0.03 RP11-284H19.1
34344
 0.2
chr2_47500188_47500420 0.03 EPCAM
 epithelial cell adhesion molecule
 71993
 0.09
chr5_167248531_167248682 0.03 ENSG00000221741
 .
 49064
 0.14
chr1_28919373_28919559 0.03 RAB42
 RAB42, member RAS oncogene family
 754
 0.51
chr19_51231309_51231608 0.03 CLEC11A
 C-type lectin domain family 11, member A
 4678
 0.12
chr19_41329835_41330195 0.03 EGLN2
 egl-9 family hypoxia-inducible factor 2
 16867
 0.11
chr1_204158879_204159072 0.03 KISS1
 KiSS-1 metastasis-suppressor
 6639
 0.15
chr3_148585148_148585299 0.03 CPA3
 carboxypeptidase A3 (mast cell)
 2180
 0.36
chr8_13115208_13115359 0.03 DLC1
 deleted in liver cancer 1
 18772
 0.25
chr11_11610992_11611143 0.03 RP11-483L5.1
19436
 0.21
chr7_6474403_6474587 0.03 DAGLB
 diacylglycerol lipase, beta
 13068
 0.16
chr5_54867827_54868108 0.03 PPAP2A
 phosphatidic acid phosphatase type 2A
 37089
 0.17
chr10_111751358_111751641 0.03 ENSG00000263706
 .
 12513
 0.18
chr2_173139735_173139887 0.03 ENSG00000238572
 .
 118963
 0.05
chr2_43233940_43234091 0.03 ENSG00000207087
 .
 84617
 0.1
chr11_103774710_103774942 0.03 RP11-617B3.2
41450
 0.18
chr10_131681520_131681924 0.03 ENSG00000266676
 .
 40084
 0.18
chr14_39335871_39336022 0.03 ENSG00000199285
 .
 120539
 0.06
chr4_139156204_139156442 0.03 SLC7A11
 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
 7180
 0.31
chr2_232571942_232572093 0.03 PTMA
 prothymosin, alpha
 377
 0.48
chr6_146285006_146285157 0.03 SHPRH
 SNF2 histone linker PHD RING helicase, E3 ubiquitin protein ligase
 152
 0.97
chr19_12809158_12809309 0.03 FBXW9
 F-box and WD repeat domain containing 9
 1776
 0.14
chr11_78021684_78021846 0.03 RP11-452H21.1
14039
 0.18
chr8_107299673_107299824 0.03 OXR1
 oxidation resistance 1
 17275
 0.3
chr10_114747236_114747430 0.03 RP11-57H14.2
35699
 0.18
chr2_27110278_27110603 0.03 DPYSL5
 dihydropyrimidinase-like 5
 39064
 0.12
chr15_58160193_58160344 0.03 ALDH1A2
 aldehyde dehydrogenase 1 family, member A2
 146031
 0.04
chr6_27143884_27144131 0.03 ENSG00000265565
 .
 28602
 0.1
chr16_12096454_12096617 0.03 RP11-166B2.7
24828
 0.11
chr1_45940556_45940894 0.03 TESK2
 testis-specific kinase 2
 16090
 0.14
chr1_95007732_95008585 0.03 F3
 coagulation factor III (thromboplastin, tissue factor)
 802
 0.76
chr20_35903692_35903888 0.03 GHRH
 growth hormone releasing hormone
 13552
 0.18
chr7_40337996_40338297 0.03 SUGCT
 succinylCoA:glutarate-CoA transferase
 163527
 0.04
chr14_93651677_93652183 0.03 TMEM251
 transmembrane protein 251
 572
 0.33
chr19_51748907_51749058 0.03 SIGLECL1
 SIGLEC family like 1
 621
 0.55
chr7_129710940_129711854 0.03 KLHDC10
 kelch domain containing 10
 785
 0.58
chr11_120822754_120822905 0.03 RP11-640N11.2
57323
 0.15
chr9_73170403_73170554 0.03 ENSG00000272232
 .
 23899
 0.25
chr2_105593697_105593939 0.03 ENSG00000263685
 .
 15620
 0.19
chr14_74981270_74981555 0.03 LTBP2
 latent transforming growth factor beta binding protein 2
 4902
 0.17
chr5_34864010_34864161 0.03 CTD-2517O10.6
24702
 0.15
chr22_35767629_35767792 0.03 HMOX1
 heme oxygenase (decycling) 1
 8644
 0.18
chr14_35874255_35874406 0.03 NFKBIA
 nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
 378
 0.91
chr2_114132740_114132924 0.03 IGKV1OR2-108
 immunoglobulin kappa variable 1/OR2-108 (non-functional)
 31141
 0.14
chr14_62063396_62063547 0.03 RP11-47I22.3
 Uncharacterized protein
 26157
 0.19
chr13_21593056_21593207 0.03 LATS2-AS1
 LATS2 antisense RNA 1
 13835
 0.14

Histogram of CRE-TSS distances for CREs targeted by :

Histogram of

Rank distribution of CRE target scores:

Histogram of target CRE score.

Distribution of target CREs across different genomic regions:

Weighted Piechart of Weighted Piechart of Weighted Piechart of

Network of associatons between targets according to the STRING database.

First level regulatory network of RBPJ

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.0 GO:0030210 heparin biosynthetic process(GO:0030210)
0.0 0.0 GO:0019276 UDP-N-acetylgalactosamine metabolic process(GO:0019276)
0.0 0.0 GO:0070427 nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070427)
0.0 0.0 GO:0045198 establishment of epithelial cell apical/basal polarity(GO:0045198)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.0 GO:0004370 glycerol kinase activity(GO:0004370)