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ENCODE: H3K4me1 ChIP-Seq of primary human cells
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CREMA is a free online tool that recognizes most important transcription factors that change the chromatin state across different samples.

Results for RUNX3_BCL11A

Z-value: 1.73

Motif logo

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Transcription factors associated with RUNX3_BCL11A

Gene Symbol Gene ID Gene Info
RUNX3
ENSG00000020633.14 RUNX3
BCL11A
ENSG00000119866.16 BCL11A

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE Gene Distance Association probability Pearson corr. coef. P-value Plot
BCL11Achr2_60774385_6077453660800.2586680.742.2e-02Click!
BCL11Achr2_60774040_6077419164250.2560530.684.4e-02Click!
BCL11Achr2_60797427_60797578168000.2262250.665.1e-02Click!
BCL11Achr2_60763897_60764048165680.2200010.655.9e-02Click!
BCL11Achr2_60758783_60758934216820.2048200.656.0e-02Click!
RUNX3chr1_25298793_2529894473670.2077640.752.1e-02Click!
RUNX3chr1_25201814_25201965537230.1283080.722.9e-02Click!
RUNX3chr1_25223736_25223887318010.1823780.693.9e-02Click!
RUNX3chr1_25191762_25191913637750.1070950.674.8e-02Click!
RUNX3chr1_25190782_25190933647550.1051920.675.0e-02Click!

Activity of the RUNX3_BCL11A motif across conditions

Conditions sorted by the z-value of the RUNX3_BCL11A motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE) Target Score Top associated gene Gene Info Distance of CRE to TSS CRE/Gene association probability
chr7_101584838_101585234 0.71 CTB-181H17.1
18360
 0.23
chr2_113637342_113637493 0.46 IL37
 interleukin 37
 33131
 0.13
chr16_66300908_66301202 0.44 ENSG00000201999
 .
 34657
 0.2
chr17_6580827_6580978 0.43 SLC13A5
 solute carrier family 13 (sodium-dependent citrate transporter), member 5
 13301
 0.1
chr2_173991432_173991997 0.39 MLTK
 Mitogen-activated protein kinase kinase kinase MLT
 36367
 0.18
chr2_207423126_207423634 0.38 ADAM23
 ADAM metallopeptidase domain 23
 36179
 0.16
chr13_110492993_110493226 0.38 IRS2
 insulin receptor substrate 2
 54194
 0.15
chr3_183563662_183564003 0.37 PARL
 presenilin associated, rhomboid-like
 1770
 0.27
chr2_64899791_64900044 0.36 SERTAD2
 SERTA domain containing 2
 18870
 0.22
chr1_88109761_88109982 0.36 ENSG00000199318
 .
 190815
 0.03
chr8_98944366_98944517 0.35 MATN2
 matrilin 2
 788
 0.7
chr3_151554111_151554262 0.35 AADAC
 arylacetamide deacetylase
 22325
 0.19
chr6_34922417_34922568 0.34 ANKS1A
 ankyrin repeat and sterile alpha motif domain containing 1A
 65412
 0.1
chr5_157482209_157482360 0.34 ENSG00000222626
 .
 78320
 0.11
chr1_33846410_33846642 0.34 PHC2
 polyhomeotic homolog 2 (Drosophila)
 5332
 0.17
chr2_159047547_159047790 0.33 CCDC148-AS1
 CCDC148 antisense RNA 1
 24506
 0.21
chr1_48048565_48048716 0.33 ENSG00000221447
 .
 38209
 0.18
chr7_131186057_131186496 0.33 RP11-180C16.1
3823
 0.33
chr13_107152902_107153053 0.33 EFNB2
 ephrin-B2
 34485
 0.22
chr13_95898832_95898983 0.32 ENSG00000238463
 .
 36309
 0.17
chr3_167659356_167659607 0.32 SERPINI1
 serpin peptidase inhibitor, clade I (neuroserpin), member 1
 134455
 0.05
chr21_16787960_16788111 0.32 ENSG00000212564
 .
 198567
 0.03
chr2_206637831_206637982 0.32 AC007362.3
9176
 0.27
chr20_4322540_4322691 0.31 ADRA1D
 adrenoceptor alpha 1D
 92894
 0.08
chr9_111249608_111249759 0.31 ENSG00000222512
 .
 128474
 0.06
chr5_99606053_99606204 0.31 ENSG00000207077
 .
 116752
 0.07
chr3_159600901_159601361 0.31 SCHIP1
 schwannomin interacting protein 1
 30403
 0.17
chr10_60420713_60420913 0.31 BICC1
 bicaudal C homolog 1 (Drosophila)
 132482
 0.05
chr10_30046717_30046886 0.31 SVIL
 supervillin
 22068
 0.23
chr5_53075823_53075974 0.31 ENSG00000263710
 .
 2630
 0.4
chr12_7176639_7176790 0.30 C1S
 complement component 1, s subcomponent
 6827
 0.12
chr8_60190503_60190654 0.30 ENSG00000206853
 .
 140517
 0.05
chr2_145128325_145128476 0.30 GTDC1
 glycosyltransferase-like domain containing 1
 38317
 0.2
chr15_78715775_78715926 0.30 IREB2
 iron-responsive element binding protein 2
 13923
 0.17
chr9_82288636_82288787 0.29 TLE4
 transducin-like enhancer of split 4 (E(sp1) homolog, Drosophila)
 21203
 0.3
chr12_1023092_1023252 0.29 WNK1
 WNK lysine deficient protein kinase 1
 13408
 0.19
chr10_30736210_30736361 0.29 MAP3K8
 mitogen-activated protein kinase kinase kinase 8
 8534
 0.23
chr15_82354959_82355110 0.29 MEX3B
 mex-3 RNA binding family member B
 16552
 0.18
chr4_83702562_83702713 0.29 SCD5
 stearoyl-CoA desaturase 5
 17272
 0.18
chr10_116285982_116286133 0.29 ABLIM1
 actin binding LIM protein 1
 537
 0.85
chr2_159902692_159902978 0.29 ENSG00000202029
 .
 19181
 0.24
chr10_126284250_126284401 0.29 FAM53B-AS1
 FAM53B antisense RNA 1
 107869
 0.06
chr2_20406865_20407016 0.29 SDC1
 syndecan 1
 17101
 0.16
chr2_95941109_95941447 0.28 PROM2
 prominin 2
 1033
 0.58
chr6_69361419_69361570 0.28 BAI3
 brain-specific angiogenesis inhibitor 3
 16235
 0.23
chr11_3021564_3021715 0.28 NAP1L4
 nucleosome assembly protein 1-like 4
 8032
 0.13
chr1_214618510_214618915 0.28 PTPN14
 protein tyrosine phosphatase, non-receptor type 14
 19434
 0.26
chr5_146603074_146603225 0.28 CTC-255N20.1
11273
 0.23
chr9_78642353_78642708 0.28 PCSK5
 proprotein convertase subtilisin/kexin type 5
 68363
 0.13
chr12_122811262_122811462 0.28 CLIP1
 CAP-GLY domain containing linker protein 1
 37202
 0.15
chr17_36611263_36611448 0.28 ARHGAP23
 Rho GTPase activating protein 23
 2289
 0.24
chr4_21770969_21771255 0.28 KCNIP4
 Kv channel interacting protein 4
 71715
 0.12
chr1_116213540_116213691 0.28 VANGL1
 VANGL planar cell polarity protein 1
 19592
 0.2
chr17_79689455_79689606 0.28 SLC25A10
 solute carrier family 25 (mitochondrial carrier; dicarboxylate transporter), member 10
 9058
 0.08
chr1_23782598_23782924 0.28 ASAP3
 ArfGAP with SH3 domain, ankyrin repeat and PH domain 3
 19591
 0.15
chr9_87324377_87324528 0.28 NTRK2
 neurotrophic tyrosine kinase, receptor, type 2
 37450
 0.24
chr6_34307108_34307266 0.28 NUDT3
 nudix (nucleoside diphosphate linked moiety X)-type motif 3
 53264
 0.11
chr8_22780218_22780369 0.28 PEBP4
 phosphatidylethanolamine-binding protein 4
 5128
 0.17
chr3_30333675_30334003 0.28 ENSG00000199927
 .
 12188
 0.3
chr17_68134107_68134311 0.27 AC002539.1
9209
 0.19
chr20_39640397_39640672 0.27 ENSG00000222612
 .
 12311
 0.22
chr4_36325181_36325757 0.27 DTHD1
 death domain containing 1
 39825
 0.17
chr19_16994459_16994610 0.27 F2RL3
 coagulation factor II (thrombin) receptor-like 3
 5137
 0.13
chr11_120214974_120215806 0.27 ARHGEF12
 Rho guanine nucleotide exchange factor (GEF) 12
 7444
 0.19
chr10_75297187_75297406 0.27 ENSG00000207327
 .
 8381
 0.13
chr8_37638673_37638989 0.27 GPR124
 G protein-coupled receptor 124
 2878
 0.2
chr4_169680615_169680766 0.27 PALLD
 palladin, cytoskeletal associated protein
 47380
 0.14
chr5_52004754_52004905 0.27 ITGA1
 integrin, alpha 1
 78901
 0.1
chr2_25601668_25601819 0.26 DNMT3A
 DNA (cytosine-5-)-methyltransferase 3 alpha
 36284
 0.16
chr2_21478794_21478945 0.26 TDRD15
 tudor domain containing 15
 132080
 0.06
chr11_37581903_37582191 0.26 ENSG00000251838
 .
 141723
 0.05
chr11_9778103_9778254 0.26 SBF2-AS1
 SBF2 antisense RNA 1
 1661
 0.36
chr17_77669704_77669855 0.26 ENSG00000266665
 .
 11279
 0.16
chr1_211806198_211806349 0.26 ENSG00000222080
 .
 20618
 0.15
chr8_97717767_97718055 0.26 CPQ
 carboxypeptidase Q
 55291
 0.16
chr13_43948647_43949015 0.26 ENOX1
 ecto-NOX disulfide-thiol exchanger 1
 13618
 0.31
chr8_78478320_78478688 0.26 ENSG00000222334
 .
 279452
 0.02
chr6_132238156_132238426 0.26 RP11-69I8.3
33795
 0.16
chr5_138280070_138280221 0.26 CTNNA1
 catenin (cadherin-associated protein), alpha 1, 102kDa
 13818
 0.2
chr9_33117236_33117610 0.26 B4GALT1
 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1
 10774
 0.16
chr1_7028963_7029357 0.26 RP11-334N17.1
45179
 0.18
chr11_36383085_36383430 0.26 PRR5L
 proline rich 5 like
 401
 0.87
chr20_10286775_10287859 0.26 ENSG00000211588
 .
 55561
 0.13
chr16_68969001_68969152 0.26 RP11-521L9.2
1353
 0.45
chr7_116712956_116713196 0.26 ST7-AS2
 ST7 antisense RNA 2
 1702
 0.37
chr1_42342644_42342801 0.26 HIVEP3
 human immunodeficiency virus type I enhancer binding protein 3
 41447
 0.2
chr21_44092560_44092754 0.25 PDE9A
 phosphodiesterase 9A
 18734
 0.17
chr7_73671010_73671161 0.25 ENSG00000252538
 .
 1861
 0.27
chr5_42675830_42675981 0.25 CCDC152
 coiled-coil domain containing 152
 80998
 0.1
chr1_248017319_248017470 0.25 TRIM58
 tripartite motif containing 58
 3107
 0.16
chr2_39858801_39859100 0.25 TMEM178A
 transmembrane protein 178A
 34109
 0.21
chr8_1450263_1450414 0.25 DLGAP2
 discs, large (Drosophila) homolog-associated protein 2
 806
 0.77
chr12_71054642_71054987 0.25 PTPRB
 protein tyrosine phosphatase, receptor type, B
 23594
 0.24
chr3_13106568_13106852 0.25 IQSEC1
 IQ motif and Sec7 domain 1
 7907
 0.3
chr6_74404500_74404761 0.25 CD109
 CD109 molecule
 878
 0.48
chr4_23946972_23947800 0.25 PPARGC1A
 peroxisome proliferator-activated receptor gamma, coactivator 1 alpha
 55686
 0.17
chr7_142008246_142008397 0.25 PRSS3P3
 protease, serine, 3 pseudogene 3
 18712
 0.21
chr4_94735703_94735854 0.25 ENSG00000252342
 .
 5544
 0.27
chr12_2754603_2754754 0.25 CACNA1C-AS2
 CACNA1C antisense RNA 2
 26708
 0.16
chr6_149081739_149081986 0.25 UST
 uronyl-2-sulfotransferase
 13398
 0.3
chr4_116196577_116196808 0.25 NDST4
 N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 4
 161660
 0.04
chr4_47521566_47521717 0.25 ATP10D
 ATPase, class V, type 10D
 34325
 0.16
chr1_25353713_25354006 0.25 ENSG00000264371
 .
 3865
 0.28
chr12_104249181_104249332 0.25 RP11-650K20.3
 Uncharacterized protein
 14027
 0.14
chr8_121016842_121017083 0.25 COL14A1
 collagen, type XIV, alpha 1
 100854
 0.07
chr2_60443628_60443779 0.25 ENSG00000200807
 .
 168037
 0.04
chr2_103104222_103104645 0.25 SLC9A4
 solute carrier family 9, subfamily A (NHE4, cation proton antiporter 4), member 4
 14671
 0.18
chr9_94137166_94137359 0.25 AUH
 AU RNA binding protein/enoyl-CoA hydratase
 13067
 0.27
chr8_117721319_117721699 0.25 EIF3H
 eukaryotic translation initiation factor 3, subunit H
 46514
 0.16
chr2_111499279_111499430 0.24 ACOXL
 acyl-CoA oxidase-like
 8922
 0.27
chr15_67094989_67095410 0.24 SMAD6
 SMAD family member 6
 91164
 0.08
chr15_98606703_98606854 0.24 ENSG00000222361
 .
 11214
 0.25
chr1_216792141_216792292 0.24 ESRRG
 estrogen-related receptor gamma
 104458
 0.08
chr3_119946202_119946353 0.24 GPR156
 G protein-coupled receptor 156
 16686
 0.19
chr3_140830382_140830533 0.24 RP11-231L11.1
12567
 0.25
chr17_63126923_63127074 0.24 RGS9
 regulator of G-protein signaling 9
 6568
 0.25
chr2_161522640_161522806 0.24 RBMS1
 RNA binding motif, single stranded interacting protein 1
 172418
 0.03
chr2_25704806_25704957 0.24 AC104699.1
60895
 0.13
chr11_36035573_36035724 0.24 ENSG00000263389
 .
 4000
 0.27
chr2_217087681_217088112 0.24 AC012513.6
36422
 0.16
chr3_190154042_190154396 0.24 TMEM207
 transmembrane protein 207
 13446
 0.23
chr5_75586743_75586894 0.24 RP11-466P24.6
20469
 0.26
chr12_25517561_25518178 0.24 ENSG00000201439
 .
 39493
 0.18
chr14_34521466_34521617 0.24 EGLN3-AS1
 EGLN3 antisense RNA 1
 12238
 0.27
chr14_25519992_25520181 0.24 STXBP6
 syntaxin binding protein 6 (amisyn)
 583
 0.86
chr7_143093219_143093370 0.24 EPHA1-AS1
 EPHA1 antisense RNA 1
 11612
 0.1
chr1_208709695_208709846 0.24 PLXNA2
 plexin A2
 292105
 0.01
chr15_40013019_40013170 0.24 RP11-37C7.3
61678
 0.1
chr1_71465412_71465563 0.24 RP3-333A15.2
6698
 0.19
chr15_66799880_66800031 0.23 ZWILCH
 zwilch kinetochore protein
 2317
 0.12
chr18_3346083_3346234 0.23 TGIF1
 TGFB-induced factor homeobox 1
 65448
 0.09
chr9_113940688_113940998 0.23 ENSG00000212409
 .
 81150
 0.1
chr11_72204731_72205079 0.23 CLPB
 ClpB caseinolytic peptidase B homolog (E. coli)
 59213
 0.09
chr1_204428957_204429108 0.23 PIK3C2B
 phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta
 7442
 0.2
chr22_28063445_28063735 0.23 RP11-375H17.1
48878
 0.18
chr1_27921837_27922130 0.23 AHDC1
 AT hook, DNA binding motif, containing 1
 8119
 0.16
chr16_16116227_16116413 0.23 ABCC1
 ATP-binding cassette, sub-family C (CFTR/MRP), member 1
 12607
 0.24
chr5_56738054_56738205 0.23 ENSG00000264748
 .
 39601
 0.15
chr16_9142329_9142480 0.23 C16orf72
 chromosome 16 open reading frame 72
 43101
 0.12
chr13_114563717_114564199 0.23 GAS6
 growth arrest-specific 6
 3082
 0.32
chr10_128777765_128777916 0.23 RP11-223P11.3
46846
 0.16
chr3_102766582_102766733 0.23 ENSG00000201922
 .
 112147
 0.08
chr14_49976614_49976898 0.23 ENSG00000252424
 .
 42595
 0.11
chr6_21065242_21065393 0.23 ENSG00000252046
 .
 71518
 0.14
chr1_16470966_16471152 0.23 RP11-276H7.2
10647
 0.12
chr5_145427169_145427320 0.23 RP11-118M9.3
51725
 0.13
chr11_77181730_77181925 0.23 DKFZP434E1119
2589
 0.26
chr1_95205288_95205439 0.23 ENSG00000263526
 .
 6093
 0.28
chr18_52474420_52474571 0.23 RAB27B
 RAB27B, member RAS oncogene family
 20935
 0.25
chr3_140955174_140955431 0.23 ACPL2
 acid phosphatase-like 2
 4584
 0.3
chr2_113643237_113643388 0.23 IL37
 interleukin 37
 27236
 0.14
chr8_118682053_118682204 0.23 MED30
 mediator complex subunit 30
 149056
 0.05
chr2_166659633_166659784 0.23 GALNT3
 UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 3 (GalNAc-T3)
 8516
 0.22
chr7_26100411_26100562 0.22 ENSG00000266430
 .
 527
 0.85
chr1_172872813_172873091 0.22 TNFSF18
 tumor necrosis factor (ligand) superfamily, member 18
 147104
 0.04
chr10_45218615_45218841 0.22 TMEM72
 transmembrane protein 72
 187920
 0.03
chr21_16507556_16507707 0.22 NRIP1
 nuclear receptor interacting protein 1
 70310
 0.13
chr15_67343283_67343434 0.22 SMAD3
 SMAD family member 3
 12743
 0.28
chr4_103463142_103463346 0.22 ENSG00000238553
 .
 23880
 0.18
chr2_233250511_233250662 0.22 ECEL1P2
 endothelin converting enzyme-like 1, pseudogene 2
 1581
 0.28
chr21_44782917_44783256 0.22 SIK1
 salt-inducible kinase 1
 63922
 0.13
chr15_42912214_42912365 0.22 STARD9
 StAR-related lipid transfer (START) domain containing 9
 44432
 0.11
chr1_208299622_208299773 0.22 PLXNA2
 plexin A2
 117968
 0.07
chr7_79780258_79780623 0.22 GNAI1
 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1
 15369
 0.27
chr2_27984512_27984663 0.22 MRPL33
 mitochondrial ribosomal protein L33
 9997
 0.16
chr8_94601215_94601366 0.22 FAM92A1
 family with sequence similarity 92, member A1
 109499
 0.05
chr8_23154100_23154303 0.22 R3HCC1
 R3H domain and coiled-coil containing 1
 6275
 0.16
chr6_157118574_157118845 0.22 RP11-230C9.3
17120
 0.19
chr8_103768541_103768692 0.22 ENSG00000266799
 .
 22669
 0.2
chr3_142379819_142379970 0.22 PLS1
 plastin 1
 4155
 0.18
chr6_168273368_168273519 0.22 MLLT4
 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 4
 7718
 0.27
chr17_53361051_53361202 0.22 RP11-515O17.2
10112
 0.24
chr4_57695109_57695260 0.22 SPINK2
 serine peptidase inhibitor, Kazal type 2 (acrosin-trypsin inhibitor)
 7276
 0.16
chr5_61878347_61878498 0.22 LRRC70
 leucine rich repeat containing 70
 3720
 0.25
chr4_106816060_106816236 0.22 NPNT
 nephronectin
 216
 0.88
chr2_173260528_173260712 0.22 ITGA6
 integrin, alpha 6
 31462
 0.17
chr3_193306986_193307190 0.22 OPA1
 optic atrophy 1 (autosomal dominant)
 3845
 0.21
chr1_41823496_41823929 0.22 FOXO6
 forkhead box O6
 3882
 0.26
chr5_1316470_1316621 0.22 ENSG00000263670
 .
 7053
 0.18
chr8_81242826_81242977 0.22 ENSG00000206649
 .
 13597
 0.23
chr7_18874739_18874890 0.22 ENSG00000222164
 .
 26912
 0.23
chr15_70620232_70620383 0.22 ENSG00000200216
 .
 134732
 0.05
chr17_16300220_16300371 0.21 RP11-138I1.4
14312
 0.12
chr14_75511240_75511466 0.21 MLH3
 mutL homolog 3
 1990
 0.22
chr4_110917795_110917946 0.21 ENSG00000207260
 .
 4389
 0.29
chr20_17582646_17582797 0.21 ENSG00000202260
 .
 25566
 0.15
chr3_124770418_124770881 0.21 HEG1
 heart development protein with EGF-like domains 1
 4153
 0.22
chr2_62521235_62521386 0.21 ENSG00000238809
 .
 29180
 0.17
chr4_73185358_73185600 0.21 RP11-373J21.1
3266
 0.4
chr12_18712270_18712421 0.21 PLCZ1
 phospholipase C, zeta 1
 135626
 0.05
chr1_155295454_155295745 0.21 RUSC1
 RUN and SH3 domain containing 1
 1231
 0.22
chr5_148131083_148131267 0.21 ADRB2
 adrenoceptor beta 2, surface
 74981
 0.1
chr10_2928332_2928483 0.21 PFKP
 phosphofructokinase, platelet
 180118
 0.03
chr2_166022390_166022679 0.21 ENSG00000264047
 .
 16551
 0.21
chr5_58950145_58950296 0.21 ENSG00000202601
 .
 49309
 0.18
chr11_14786895_14787046 0.21 PDE3B
 phosphodiesterase 3B, cGMP-inhibited
 121593
 0.05
chr3_167594407_167594558 0.21 SERPINI1
 serpin peptidase inhibitor, clade I (neuroserpin), member 1
 69456
 0.13
chr15_84033971_84034404 0.21 BNC1
 basonuclin 1
 80721
 0.09
chr6_14275779_14275930 0.21 ENSG00000238987
 .
 119161
 0.06
chr10_13924410_13924760 0.21 FRMD4A
 FERM domain containing 4A
 23673
 0.22

Histogram of CRE-TSS distances for CREs targeted by :

Histogram of

Rank distribution of CRE target scores:

Histogram of target CRE score.

Distribution of target CREs across different genomic regions:

Weighted Piechart of Weighted Piechart of Weighted Piechart of

Network of associatons between targets according to the STRING database.

StringDB image

First level regulatory network of RUNX3_BCL11A

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0060666 dichotomous subdivision of terminal units involved in salivary gland branching(GO:0060666)
0.1 0.2 GO:0001574 ganglioside biosynthetic process(GO:0001574)
0.1 0.2 GO:0051834 evasion or tolerance of host defenses by virus(GO:0019049) avoidance of host defenses(GO:0044413) evasion or tolerance of host defenses(GO:0044415) avoidance of defenses of other organism involved in symbiotic interaction(GO:0051832) evasion or tolerance of defenses of other organism involved in symbiotic interaction(GO:0051834)
0.1 0.2 GO:0006565 L-serine catabolic process(GO:0006565)
0.1 0.2 GO:0002331 pre-B cell allelic exclusion(GO:0002331)
0.0 0.1 GO:0001543 ovarian follicle rupture(GO:0001543)
0.0 0.2 GO:0018027 peptidyl-lysine dimethylation(GO:0018027)
0.0 0.1 GO:0010193 response to ozone(GO:0010193)
0.0 0.1 GO:0060686 negative regulation of prostatic bud formation(GO:0060686)
0.0 0.1 GO:0007221 positive regulation of transcription of Notch receptor target(GO:0007221)
0.0 0.2 GO:0070296 sarcoplasmic reticulum calcium ion transport(GO:0070296)
0.0 0.2 GO:0009136 ADP biosynthetic process(GO:0006172) purine nucleoside diphosphate biosynthetic process(GO:0009136) purine ribonucleoside diphosphate biosynthetic process(GO:0009180) ribonucleoside diphosphate biosynthetic process(GO:0009188)
0.0 0.1 GO:0018242 protein O-linked glycosylation via serine(GO:0018242) protein O-linked glycosylation via threonine(GO:0018243)
0.0 0.0 GO:0002677 negative regulation of chronic inflammatory response(GO:0002677)
0.0 0.1 GO:0045916 negative regulation of complement activation(GO:0045916) negative regulation of protein activation cascade(GO:2000258)
0.0 0.1 GO:0042668 auditory receptor cell fate determination(GO:0042668)
0.0 0.0 GO:0061154 endothelial tube morphogenesis(GO:0061154)
0.0 0.1 GO:0003099 positive regulation of the force of heart contraction by chemical signal(GO:0003099)
0.0 0.1 GO:0018343 protein farnesylation(GO:0018343)
0.0 0.1 GO:0045989 positive regulation of striated muscle contraction(GO:0045989)
0.0 0.1 GO:0003010 voluntary skeletal muscle contraction(GO:0003010) twitch skeletal muscle contraction(GO:0014721)
0.0 0.1 GO:0019367 fatty acid elongation, saturated fatty acid(GO:0019367)
0.0 0.2 GO:0060534 trachea cartilage development(GO:0060534)
0.0 0.1 GO:0033522 histone H2A ubiquitination(GO:0033522)
0.0 0.1 GO:0010957 negative regulation of calcidiol 1-monooxygenase activity(GO:0010956) negative regulation of vitamin D biosynthetic process(GO:0010957) negative regulation of vitamin metabolic process(GO:0046137)
0.0 0.1 GO:1903960 negative regulation of plasma membrane long-chain fatty acid transport(GO:0010748) negative regulation of anion transmembrane transport(GO:1903960) negative regulation of fatty acid transport(GO:2000192)
0.0 0.2 GO:0090050 positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050) positive regulation of sprouting angiogenesis(GO:1903672)
0.0 0.1 GO:0046813 receptor-mediated virion attachment to host cell(GO:0046813)
0.0 0.2 GO:0006610 ribosomal protein import into nucleus(GO:0006610)
0.0 0.0 GO:0071830 chylomicron remnant clearance(GO:0034382) triglyceride-rich lipoprotein particle clearance(GO:0071830)
0.0 0.2 GO:0007185 transmembrane receptor protein tyrosine phosphatase signaling pathway(GO:0007185)
0.0 0.1 GO:0006975 DNA damage induced protein phosphorylation(GO:0006975)
0.0 0.1 GO:0060039 pericardium development(GO:0060039)
0.0 0.1 GO:0048496 maintenance of organ identity(GO:0048496)
0.0 0.1 GO:0051024 positive regulation of immunoglobulin secretion(GO:0051024)
0.0 0.1 GO:0039656 modulation by virus of host gene expression(GO:0039656)
0.0 0.1 GO:0046085 adenosine metabolic process(GO:0046085)
0.0 0.1 GO:0030505 inorganic diphosphate transport(GO:0030505)
0.0 0.1 GO:0032060 bleb assembly(GO:0032060)
0.0 0.1 GO:0015801 aromatic amino acid transport(GO:0015801)
0.0 0.1 GO:0045077 negative regulation of interferon-gamma biosynthetic process(GO:0045077)
0.0 0.2 GO:0042487 regulation of odontogenesis of dentin-containing tooth(GO:0042487)
0.0 0.1 GO:0051570 regulation of histone H3-K9 methylation(GO:0051570)
0.0 0.1 GO:0055022 negative regulation of cardiac muscle tissue growth(GO:0055022) negative regulation of cardiac muscle tissue development(GO:0055026) negative regulation of cardiac muscle cell proliferation(GO:0060044) negative regulation of heart growth(GO:0061117)
0.0 0.1 GO:2000143 negative regulation of transcription initiation from RNA polymerase II promoter(GO:0060633) negative regulation of DNA-templated transcription, initiation(GO:2000143)
0.0 0.1 GO:0070634 transepithelial ammonium transport(GO:0070634)
0.0 0.1 GO:0045662 negative regulation of myoblast differentiation(GO:0045662)
0.0 0.1 GO:0046882 negative regulation of follicle-stimulating hormone secretion(GO:0046882)
0.0 0.1 GO:0010757 negative regulation of plasminogen activation(GO:0010757)
0.0 0.0 GO:1903670 regulation of cell migration involved in sprouting angiogenesis(GO:0090049) regulation of sprouting angiogenesis(GO:1903670)
0.0 0.1 GO:0045162 clustering of voltage-gated sodium channels(GO:0045162)
0.0 0.2 GO:0043537 negative regulation of blood vessel endothelial cell migration(GO:0043537)
0.0 0.1 GO:0071364 cellular response to epidermal growth factor stimulus(GO:0071364)
0.0 0.0 GO:0032278 positive regulation of gonadotropin secretion(GO:0032278) positive regulation of follicle-stimulating hormone secretion(GO:0046881)
0.0 0.1 GO:0010511 regulation of phosphatidylinositol biosynthetic process(GO:0010511)
0.0 0.1 GO:0031223 response to auditory stimulus(GO:0010996) auditory behavior(GO:0031223)
0.0 0.1 GO:0002420 natural killer cell mediated cytotoxicity directed against tumor cell target(GO:0002420) natural killer cell mediated immune response to tumor cell(GO:0002423) regulation of natural killer cell mediated immune response to tumor cell(GO:0002855) positive regulation of natural killer cell mediated immune response to tumor cell(GO:0002857) regulation of natural killer cell mediated cytotoxicity directed against tumor cell target(GO:0002858) positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target(GO:0002860)
0.0 0.0 GO:0002043 blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:0002043)
0.0 0.1 GO:0060762 regulation of branching involved in mammary gland duct morphogenesis(GO:0060762)
0.0 0.0 GO:0051387 negative regulation of neurotrophin TRK receptor signaling pathway(GO:0051387)
0.0 0.1 GO:0046501 protoporphyrinogen IX metabolic process(GO:0046501)
0.0 0.1 GO:0043457 regulation of cellular respiration(GO:0043457)
0.0 0.1 GO:0034638 phosphatidylcholine catabolic process(GO:0034638)
0.0 0.1 GO:0045425 positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process(GO:0045425)
0.0 0.0 GO:0032277 negative regulation of gonadotropin secretion(GO:0032277)
0.0 0.0 GO:0002693 positive regulation of cellular extravasation(GO:0002693)
0.0 0.1 GO:0032455 nerve growth factor processing(GO:0032455)
0.0 0.1 GO:0045654 positive regulation of megakaryocyte differentiation(GO:0045654) positive regulation of hematopoietic progenitor cell differentiation(GO:1901534)
0.0 0.1 GO:0018101 protein citrullination(GO:0018101)
0.0 0.1 GO:0009804 phenylpropanoid metabolic process(GO:0009698) coumarin metabolic process(GO:0009804)
0.0 0.0 GO:0051176 positive regulation of sulfur metabolic process(GO:0051176)
0.0 0.2 GO:0002040 sprouting angiogenesis(GO:0002040)
0.0 0.0 GO:0033622 integrin activation(GO:0033622)
0.0 0.0 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.0 0.2 GO:0033631 cell-cell adhesion mediated by integrin(GO:0033631)
0.0 0.1 GO:0071168 protein localization to chromatin(GO:0071168)
0.0 0.0 GO:0035588 adenosine receptor signaling pathway(GO:0001973) G-protein coupled purinergic receptor signaling pathway(GO:0035588)
0.0 0.1 GO:0071681 response to indole-3-methanol(GO:0071680) cellular response to indole-3-methanol(GO:0071681)
0.0 0.1 GO:0009414 response to water deprivation(GO:0009414)
0.0 0.1 GO:0006106 fumarate metabolic process(GO:0006106)
0.0 0.1 GO:0048289 isotype switching to IgE isotypes(GO:0048289) regulation of isotype switching to IgE isotypes(GO:0048293)
0.0 0.0 GO:0009111 vitamin catabolic process(GO:0009111) fat-soluble vitamin catabolic process(GO:0042363)
0.0 0.0 GO:0014045 establishment of endothelial blood-brain barrier(GO:0014045) central nervous system vasculogenesis(GO:0022009)
0.0 0.1 GO:0032020 ISG15-protein conjugation(GO:0032020)
0.0 0.1 GO:0033169 histone H3-K9 demethylation(GO:0033169)
0.0 0.1 GO:0032310 regulation of icosanoid secretion(GO:0032303) positive regulation of icosanoid secretion(GO:0032305) regulation of prostaglandin secretion(GO:0032306) positive regulation of prostaglandin secretion(GO:0032308) prostaglandin secretion(GO:0032310)
0.0 0.1 GO:0035610 C-terminal protein deglutamylation(GO:0035609) protein side chain deglutamylation(GO:0035610)
0.0 0.1 GO:0019886 antigen processing and presentation of exogenous peptide antigen via MHC class II(GO:0019886)
0.0 0.2 GO:0009312 oligosaccharide biosynthetic process(GO:0009312)
0.0 0.1 GO:0002328 pro-B cell differentiation(GO:0002328)
0.0 0.1 GO:0060009 Sertoli cell development(GO:0060009)
0.0 0.1 GO:0047484 regulation of response to osmotic stress(GO:0047484)
0.0 0.0 GO:0046121 deoxyribonucleoside catabolic process(GO:0046121)
0.0 0.1 GO:0034214 protein hexamerization(GO:0034214)
0.0 0.0 GO:0032776 DNA methylation on cytosine(GO:0032776) C-5 methylation of cytosine(GO:0090116)
0.0 0.1 GO:0016559 peroxisome fission(GO:0016559)
0.0 0.1 GO:0022617 extracellular matrix disassembly(GO:0022617)
0.0 0.1 GO:0005981 regulation of glycogen catabolic process(GO:0005981)
0.0 0.1 GO:0006729 tetrahydrobiopterin biosynthetic process(GO:0006729)
0.0 0.0 GO:0042268 regulation of cytolysis(GO:0042268)
0.0 0.1 GO:0001945 lymph vessel development(GO:0001945)
0.0 0.0 GO:0006531 aspartate metabolic process(GO:0006531) aspartate catabolic process(GO:0006533)
0.0 0.1 GO:0046113 nucleobase catabolic process(GO:0046113)
0.0 0.1 GO:0008300 isoprenoid catabolic process(GO:0008300)
0.0 0.1 GO:0090162 establishment of epithelial cell polarity(GO:0090162)
0.0 0.0 GO:0010891 negative regulation of sequestering of triglyceride(GO:0010891)
0.0 0.0 GO:0051124 synaptic growth at neuromuscular junction(GO:0051124)
0.0 0.1 GO:0048268 clathrin coat assembly(GO:0048268)
0.0 0.0 GO:0006222 UMP biosynthetic process(GO:0006222) pyrimidine ribonucleoside monophosphate metabolic process(GO:0009173) pyrimidine ribonucleoside monophosphate biosynthetic process(GO:0009174) UMP metabolic process(GO:0046049)
0.0 0.0 GO:0006883 cellular sodium ion homeostasis(GO:0006883)
0.0 0.0 GO:0007621 negative regulation of female receptivity(GO:0007621)
0.0 0.2 GO:0015701 bicarbonate transport(GO:0015701)
0.0 0.0 GO:0044240 multicellular organism lipid catabolic process(GO:0044240)
0.0 0.0 GO:0048368 lateral mesoderm development(GO:0048368)
0.0 0.1 GO:0010898 positive regulation of triglyceride catabolic process(GO:0010898)
0.0 0.0 GO:0032516 positive regulation of phosphoprotein phosphatase activity(GO:0032516)
0.0 0.1 GO:0032232 negative regulation of actin filament bundle assembly(GO:0032232)
0.0 0.0 GO:0032641 lymphotoxin A production(GO:0032641) lymphotoxin A biosynthetic process(GO:0042109)
0.0 0.0 GO:0006667 sphinganine metabolic process(GO:0006667)
0.0 0.3 GO:0042744 hydrogen peroxide catabolic process(GO:0042744)
0.0 0.0 GO:0032849 positive regulation of cellular pH reduction(GO:0032849)
0.0 0.0 GO:0060433 bronchus development(GO:0060433)
0.0 0.0 GO:0021555 midbrain-hindbrain boundary morphogenesis(GO:0021555)
0.0 0.2 GO:0017187 peptidyl-glutamic acid carboxylation(GO:0017187) protein carboxylation(GO:0018214)
0.0 0.1 GO:0010658 striated muscle cell apoptotic process(GO:0010658) cardiac muscle cell apoptotic process(GO:0010659) regulation of striated muscle cell apoptotic process(GO:0010662) negative regulation of striated muscle cell apoptotic process(GO:0010664) regulation of cardiac muscle cell apoptotic process(GO:0010665) negative regulation of cardiac muscle cell apoptotic process(GO:0010667)
0.0 0.1 GO:0051382 kinetochore assembly(GO:0051382)
0.0 0.0 GO:0010700 negative regulation of norepinephrine secretion(GO:0010700)
0.0 0.0 GO:0070669 response to interleukin-2(GO:0070669)
0.0 0.1 GO:0090400 stress-induced premature senescence(GO:0090400)
0.0 0.1 GO:0000301 retrograde transport, vesicle recycling within Golgi(GO:0000301)
0.0 0.1 GO:0000729 DNA double-strand break processing(GO:0000729)
0.0 0.2 GO:0034605 cellular response to heat(GO:0034605)
0.0 0.0 GO:1903332 regulation of protein folding(GO:1903332)
0.0 0.0 GO:2000008 regulation of protein localization to cell surface(GO:2000008)
0.0 0.1 GO:0006572 tyrosine catabolic process(GO:0006572)
0.0 0.1 GO:0035162 embryonic hemopoiesis(GO:0035162)
0.0 0.1 GO:0043097 pyrimidine-containing compound salvage(GO:0008655) pyrimidine nucleoside salvage(GO:0043097)
0.0 0.0 GO:0007352 zygotic specification of dorsal/ventral axis(GO:0007352)
0.0 0.0 GO:0006922 obsolete cleavage of lamin involved in execution phase of apoptosis(GO:0006922)
0.0 0.0 GO:0021819 layer formation in cerebral cortex(GO:0021819)
0.0 0.1 GO:0090103 cochlea morphogenesis(GO:0090103)
0.0 0.1 GO:1901976 regulation of cell cycle checkpoint(GO:1901976)
0.0 0.1 GO:0045725 positive regulation of glycogen biosynthetic process(GO:0045725) positive regulation of glycogen metabolic process(GO:0070875)
0.0 0.0 GO:0046618 drug export(GO:0046618)
0.0 0.0 GO:0051045 negative regulation of membrane protein ectodomain proteolysis(GO:0051045)
0.0 0.0 GO:0032927 positive regulation of activin receptor signaling pathway(GO:0032927)
0.0 0.0 GO:0033262 regulation of nuclear cell cycle DNA replication(GO:0033262)
0.0 0.0 GO:0035624 receptor transactivation(GO:0035624) epidermal growth factor-activated receptor transactivation by G-protein coupled receptor signaling pathway(GO:0035625)
0.0 0.0 GO:0007440 foregut morphogenesis(GO:0007440) embryonic foregut morphogenesis(GO:0048617)
0.0 0.0 GO:0014850 response to muscle activity(GO:0014850)
0.0 0.0 GO:0032148 activation of protein kinase B activity(GO:0032148)
0.0 0.1 GO:0050435 beta-amyloid metabolic process(GO:0050435)
0.0 0.0 GO:0001675 acrosome assembly(GO:0001675)
0.0 0.1 GO:0048339 paraxial mesoderm development(GO:0048339)
0.0 0.1 GO:0001569 patterning of blood vessels(GO:0001569)
0.0 0.0 GO:0007638 mechanosensory behavior(GO:0007638)
0.0 0.0 GO:0043438 acetoacetic acid metabolic process(GO:0043438)
0.0 0.2 GO:0019433 triglyceride catabolic process(GO:0019433)
0.0 0.1 GO:0051151 negative regulation of smooth muscle cell differentiation(GO:0051151)
0.0 0.0 GO:0071502 cellular response to temperature stimulus(GO:0071502)
0.0 0.0 GO:0010701 positive regulation of norepinephrine secretion(GO:0010701)
0.0 0.1 GO:0061384 heart trabecula formation(GO:0060347) heart trabecula morphogenesis(GO:0061384)
0.0 0.1 GO:0045879 negative regulation of smoothened signaling pathway(GO:0045879)
0.0 0.0 GO:0031340 positive regulation of vesicle fusion(GO:0031340)
0.0 0.0 GO:0045618 positive regulation of keratinocyte differentiation(GO:0045618)
0.0 0.0 GO:0016188 synaptic vesicle maturation(GO:0016188)
0.0 0.0 GO:0006552 leucine catabolic process(GO:0006552)
0.0 0.1 GO:0060023 soft palate development(GO:0060023)
0.0 0.0 GO:0019805 quinolinate biosynthetic process(GO:0019805)
0.0 0.1 GO:0000266 mitochondrial fission(GO:0000266)
0.0 0.0 GO:0033173 calcineurin-NFAT signaling cascade(GO:0033173)
0.0 0.0 GO:0006295 nucleotide-excision repair, DNA incision, 3'-to lesion(GO:0006295)
0.0 0.0 GO:0002903 negative regulation of B cell apoptotic process(GO:0002903)
0.0 0.0 GO:0031063 regulation of histone deacetylation(GO:0031063)
0.0 0.1 GO:0016255 attachment of GPI anchor to protein(GO:0016255)
0.0 0.0 GO:0071277 cellular response to calcium ion(GO:0071277)
0.0 0.0 GO:0010457 centriole-centriole cohesion(GO:0010457)
0.0 0.1 GO:0032459 regulation of protein oligomerization(GO:0032459)
0.0 0.1 GO:0045070 positive regulation of viral genome replication(GO:0045070)
0.0 0.2 GO:0045103 intermediate filament-based process(GO:0045103)
0.0 0.1 GO:0007379 segment specification(GO:0007379)
0.0 0.0 GO:0044803 multi-organism membrane organization(GO:0044803)
0.0 0.1 GO:0006477 protein sulfation(GO:0006477)
0.0 0.0 GO:0007000 nucleolus organization(GO:0007000)
0.0 0.0 GO:0002326 B cell lineage commitment(GO:0002326)
0.0 0.0 GO:0048388 endosomal lumen acidification(GO:0048388)
0.0 0.1 GO:0055057 neuronal stem cell division(GO:0036445) neuroblast division(GO:0055057)
0.0 0.1 GO:0000012 single strand break repair(GO:0000012)
0.0 0.3 GO:0000188 inactivation of MAPK activity(GO:0000188)
0.0 0.0 GO:0007258 JUN phosphorylation(GO:0007258)
0.0 0.4 GO:0017157 regulation of exocytosis(GO:0017157)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.0 GO:0071664 catenin-TCF7L2 complex(GO:0071664)
0.0 0.1 GO:0071942 XPC complex(GO:0071942)
0.0 0.1 GO:0002139 stereocilia coupling link(GO:0002139) stereocilia ankle link(GO:0002141) stereocilia ankle link complex(GO:0002142)
0.0 0.2 GO:0005915 zonula adherens(GO:0005915)
0.0 0.1 GO:0048179 activin receptor complex(GO:0048179)
0.0 0.2 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.0 0.1 GO:0030061 mitochondrial crista(GO:0030061)
0.0 0.1 GO:0005883 neurofilament(GO:0005883)
0.0 0.1 GO:0005663 DNA replication factor C complex(GO:0005663)
0.0 0.1 GO:0016589 NURF complex(GO:0016589)
0.0 0.2 GO:0042589 zymogen granule membrane(GO:0042589)
0.0 0.1 GO:0032593 insulin-responsive compartment(GO:0032593)
0.0 0.1 GO:0071437 invadopodium(GO:0071437)
0.0 0.1 GO:0043259 laminin-10 complex(GO:0043259)
0.0 0.1 GO:0046581 intercellular canaliculus(GO:0046581)
0.0 0.1 GO:0005652 nuclear lamina(GO:0005652)
0.0 0.1 GO:0000275 mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275)
0.0 0.1 GO:0000138 Golgi trans cisterna(GO:0000138)
0.0 0.1 GO:0032449 CBM complex(GO:0032449)
0.0 0.1 GO:0005945 6-phosphofructokinase complex(GO:0005945)
0.0 0.1 GO:0033162 melanosome membrane(GO:0033162) chitosome(GO:0045009)
0.0 0.4 GO:0005796 Golgi lumen(GO:0005796)
0.0 0.2 GO:0017119 Golgi transport complex(GO:0017119)
0.0 0.1 GO:0045273 mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)(GO:0005749) succinate dehydrogenase complex (ubiquinone)(GO:0045257) respiratory chain complex II(GO:0045273) succinate dehydrogenase complex(GO:0045281) fumarate reductase complex(GO:0045283)
0.0 0.1 GO:0042765 GPI-anchor transamidase complex(GO:0042765)
0.0 0.2 GO:0008278 cohesin complex(GO:0008278)
0.0 0.0 GO:0000306 extrinsic component of vacuolar membrane(GO:0000306) extrinsic component of endosome membrane(GO:0031313)
0.0 0.1 GO:0030056 hemidesmosome(GO:0030056)
0.0 0.1 GO:0031254 uropod(GO:0001931) cell trailing edge(GO:0031254)
0.0 0.1 GO:0005862 muscle thin filament tropomyosin(GO:0005862)
0.0 0.1 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.0 0.2 GO:0031528 microvillus membrane(GO:0031528)
0.0 0.1 GO:0005614 interstitial matrix(GO:0005614)
0.0 0.2 GO:0005852 eukaryotic translation initiation factor 3 complex(GO:0005852)
0.0 0.1 GO:0031095 platelet dense tubular network membrane(GO:0031095)
0.0 0.0 GO:0045254 pyruvate dehydrogenase complex(GO:0045254)
0.0 0.1 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.0 0.0 GO:0032444 activin responsive factor complex(GO:0032444)
0.0 0.0 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
0.0 0.1 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.0 0.0 GO:0042587 glycogen granule(GO:0042587)
0.0 0.1 GO:0002080 acrosomal membrane(GO:0002080)
0.0 0.1 GO:0005655 nucleolar ribonuclease P complex(GO:0005655) ribonuclease P complex(GO:0030677) multimeric ribonuclease P complex(GO:0030681)
0.0 0.3 GO:0098636 integrin complex(GO:0008305) protein complex involved in cell adhesion(GO:0098636)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0001098 basal transcription machinery binding(GO:0001098) basal RNA polymerase II transcription machinery binding(GO:0001099)
0.1 0.2 GO:0003941 L-serine ammonia-lyase activity(GO:0003941)
0.1 0.2 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 0.2 GO:0030618 transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity(GO:0030618)
0.0 0.1 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
0.0 0.2 GO:0030172 troponin C binding(GO:0030172)
0.0 0.2 GO:0048018 receptor agonist activity(GO:0048018)
0.0 0.1 GO:0004117 calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117)
0.0 0.1 GO:0030297 transmembrane receptor protein tyrosine kinase activator activity(GO:0030297)
0.0 0.1 GO:0005432 calcium:sodium antiporter activity(GO:0005432)
0.0 0.1 GO:0015204 urea transmembrane transporter activity(GO:0015204)
0.0 0.2 GO:0017154 semaphorin receptor activity(GO:0017154)
0.0 0.1 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.0 0.1 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.0 0.1 GO:0031685 adenosine receptor binding(GO:0031685)
0.0 0.1 GO:0005030 neurotrophin receptor activity(GO:0005030)
0.0 0.1 GO:0033170 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.0 0.1 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.0 0.1 GO:0016361 activin receptor activity, type I(GO:0016361)
0.0 0.1 GO:0000900 translation repressor activity, nucleic acid binding(GO:0000900)
0.0 0.2 GO:0030506 ankyrin binding(GO:0030506)
0.0 0.1 GO:0008559 xenobiotic-transporting ATPase activity(GO:0008559) xenobiotic transporter activity(GO:0042910)
0.0 0.1 GO:0016715 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen(GO:0016715)
0.0 0.1 GO:0015142 citrate transmembrane transporter activity(GO:0015137) tricarboxylic acid transmembrane transporter activity(GO:0015142)
0.0 0.1 GO:0051733 ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity(GO:0046404) polydeoxyribonucleotide kinase activity(GO:0051733) ATP-dependent polynucleotide kinase activity(GO:0051734)
0.0 0.2 GO:0005021 vascular endothelial growth factor-activated receptor activity(GO:0005021)
0.0 0.1 GO:0004849 uridine kinase activity(GO:0004849)
0.0 0.1 GO:0005152 interleukin-1 receptor antagonist activity(GO:0005152)
0.0 0.1 GO:0055077 gap junction hemi-channel activity(GO:0055077)
0.0 0.1 GO:0004032 alditol:NADP+ 1-oxidoreductase activity(GO:0004032)
0.0 0.1 GO:0002162 dystroglycan binding(GO:0002162)
0.0 0.1 GO:0004528 phosphodiesterase I activity(GO:0004528)
0.0 0.1 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.0 0.1 GO:0048027 mRNA 5'-UTR binding(GO:0048027)
0.0 0.1 GO:0004668 protein-arginine deiminase activity(GO:0004668)
0.0 0.1 GO:0050682 AF-2 domain binding(GO:0050682)
0.0 0.1 GO:0004523 RNA-DNA hybrid ribonuclease activity(GO:0004523)
0.0 0.1 GO:0043422 protein kinase B binding(GO:0043422)
0.0 0.1 GO:0008321 Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.0 0.1 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454)
0.0 0.1 GO:0016308 1-phosphatidylinositol-4-phosphate 5-kinase activity(GO:0016308)
0.0 0.1 GO:0004948 calcitonin receptor activity(GO:0004948)
0.0 0.1 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
0.0 0.3 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.0 0.1 GO:0004185 serine-type carboxypeptidase activity(GO:0004185)
0.0 0.1 GO:0050544 arachidonic acid binding(GO:0050544)
0.0 0.1 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.0 0.1 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.0 0.2 GO:0005391 sodium:potassium-exchanging ATPase activity(GO:0005391)
0.0 0.1 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.0 0.1 GO:0005315 inorganic phosphate transmembrane transporter activity(GO:0005315)
0.0 0.1 GO:0009922 fatty acid elongase activity(GO:0009922)
0.0 0.0 GO:0042799 histone methyltransferase activity (H4-K20 specific)(GO:0042799)
0.0 0.1 GO:0003872 6-phosphofructokinase activity(GO:0003872)
0.0 0.1 GO:0043398 HLH domain binding(GO:0043398)
0.0 0.1 GO:0051380 norepinephrine binding(GO:0051380)
0.0 0.1 GO:0003918 DNA topoisomerase type II (ATP-hydrolyzing) activity(GO:0003918) DNA topoisomerase II activity(GO:0061505)
0.0 0.0 GO:0070643 vitamin D3 25-hydroxylase activity(GO:0030343) vitamin D 25-hydroxylase activity(GO:0070643)
0.0 0.3 GO:0008373 sialyltransferase activity(GO:0008373)
0.0 0.1 GO:0008266 poly(U) RNA binding(GO:0008266)
0.0 0.0 GO:0016909 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.0 0.0 GO:0008934 inositol monophosphate 1-phosphatase activity(GO:0008934) inositol monophosphate phosphatase activity(GO:0052834)
0.0 0.2 GO:0001619 obsolete lysosphingolipid and lysophosphatidic acid receptor activity(GO:0001619)
0.0 0.1 GO:0008526 phosphatidylinositol transporter activity(GO:0008526)
0.0 0.0 GO:0016215 stearoyl-CoA 9-desaturase activity(GO:0004768) acyl-CoA desaturase activity(GO:0016215)
0.0 0.0 GO:0004967 glucagon receptor activity(GO:0004967)
0.0 0.1 GO:0016635 oxidoreductase activity, acting on the CH-CH group of donors, quinone or related compound as acceptor(GO:0016635)
0.0 0.0 GO:0005275 amine transmembrane transporter activity(GO:0005275)
0.0 0.0 GO:0070644 vitamin D response element binding(GO:0070644)
0.0 0.0 GO:0050542 icosanoid binding(GO:0050542) fatty acid derivative binding(GO:1901567)
0.0 0.3 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.0 0.1 GO:0005010 insulin-like growth factor-activated receptor activity(GO:0005010)
0.0 0.1 GO:0005384 manganese ion transmembrane transporter activity(GO:0005384)
0.0 0.2 GO:0042288 MHC class I protein binding(GO:0042288)
0.0 0.1 GO:0016668 oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor(GO:0016668)
0.0 0.1 GO:0003923 GPI-anchor transamidase activity(GO:0003923)
0.0 0.1 GO:0046965 retinoid X receptor binding(GO:0046965)
0.0 0.1 GO:0044390 ubiquitin conjugating enzyme binding(GO:0031624) ubiquitin-like protein conjugating enzyme binding(GO:0044390)
0.0 0.1 GO:0031821 G-protein coupled serotonin receptor binding(GO:0031821)
0.0 0.1 GO:0045499 chemorepellent activity(GO:0045499)
0.0 0.0 GO:0035673 oligopeptide transmembrane transporter activity(GO:0035673)
0.0 0.1 GO:0015280 ligand-gated sodium channel activity(GO:0015280)
0.0 0.1 GO:0004331 fructose-2,6-bisphosphate 2-phosphatase activity(GO:0004331)
0.0 0.1 GO:0008499 UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity(GO:0008499)
0.0 0.0 GO:0008179 adenylate cyclase binding(GO:0008179)
0.0 0.1 GO:0004596 peptide alpha-N-acetyltransferase activity(GO:0004596)
0.0 0.0 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.0 0.1 GO:0008420 CTD phosphatase activity(GO:0008420)
0.0 0.0 GO:0008900 hydrogen:potassium-exchanging ATPase activity(GO:0008900)
0.0 0.2 GO:0051018 protein kinase A binding(GO:0051018)
0.0 0.0 GO:0016647 oxidoreductase activity, acting on the CH-NH group of donors, oxygen as acceptor(GO:0016647)
0.0 0.2 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding(GO:0005546)
0.0 0.0 GO:0097642 calcitonin family receptor activity(GO:0097642)
0.0 0.1 GO:0044548 S100 protein binding(GO:0044548)
0.0 0.0 GO:0004430 1-phosphatidylinositol 4-kinase activity(GO:0004430)
0.0 0.0 GO:0042808 obsolete neuronal Cdc2-like kinase binding(GO:0042808)
0.0 0.1 GO:0042153 obsolete RPTP-like protein binding(GO:0042153)
0.0 0.0 GO:0004103 choline kinase activity(GO:0004103)
0.0 0.0 GO:0033829 O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.0 0.0 GO:0070576 vitamin D 24-hydroxylase activity(GO:0070576)
0.0 0.1 GO:0004661 protein geranylgeranyltransferase activity(GO:0004661)
0.0 0.1 GO:0008143 poly(A) binding(GO:0008143)
0.0 0.0 GO:0004937 alpha1-adrenergic receptor activity(GO:0004937)
0.0 0.2 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.0 0.0 GO:0005148 prolactin receptor binding(GO:0005148)
0.0 0.1 GO:0050811 GABA receptor binding(GO:0050811)
0.0 0.0 GO:0015254 glycerol channel activity(GO:0015254)
0.0 0.2 GO:0008603 cAMP-dependent protein kinase regulator activity(GO:0008603)
0.0 0.0 GO:0048406 nerve growth factor binding(GO:0048406)
0.0 0.1 GO:0010853 cyclase activator activity(GO:0010853) guanylate cyclase activator activity(GO:0030250)
0.0 0.1 GO:0017166 vinculin binding(GO:0017166)
0.0 0.1 GO:0031593 polyubiquitin binding(GO:0031593)
0.0 0.0 GO:0004470 malic enzyme activity(GO:0004470)
0.0 0.1 GO:0046875 ephrin receptor binding(GO:0046875)
0.0 0.0 GO:0000033 alpha-1,3-mannosyltransferase activity(GO:0000033)
0.0 0.1 GO:0004035 alkaline phosphatase activity(GO:0004035)
0.0 0.1 GO:0043395 heparan sulfate proteoglycan binding(GO:0043395)
0.0 0.1 GO:0016725 oxidoreductase activity, acting on CH or CH2 groups(GO:0016725)
0.0 0.0 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.0 0.0 GO:0032558 purine deoxyribonucleotide binding(GO:0032554) adenyl deoxyribonucleotide binding(GO:0032558)
0.0 0.6 GO:0005178 integrin binding(GO:0005178)
0.0 0.0 GO:0015216 adenine nucleotide transmembrane transporter activity(GO:0000295) purine nucleotide transmembrane transporter activity(GO:0015216)
0.0 0.1 GO:0008294 calcium- and calmodulin-responsive adenylate cyclase activity(GO:0008294)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.0 PID GLYPICAN 1PATHWAY Glypican 1 network
0.0 0.1 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.0 0.0 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.0 0.0 PID ER NONGENOMIC PATHWAY Plasma membrane estrogen receptor signaling
0.0 0.2 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.0 0.2 PID S1P S1P1 PATHWAY S1P1 pathway
0.0 0.0 PID CXCR3 PATHWAY CXCR3-mediated signaling events
0.0 0.3 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0 0.0 PID IL5 PATHWAY IL5-mediated signaling events
0.0 0.4 PID INTEGRIN CS PATHWAY Integrin family cell surface interactions
0.0 0.0 PID S1P S1P2 PATHWAY S1P2 pathway
0.0 0.2 PID ARF6 DOWNSTREAM PATHWAY Arf6 downstream pathway
0.0 0.0 SA TRKA RECEPTOR The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth.
0.0 0.1 PID INTEGRIN1 PATHWAY Beta1 integrin cell surface interactions
0.0 0.1 PID ANGIOPOIETIN RECEPTOR PATHWAY Angiopoietin receptor Tie2-mediated signaling
0.0 0.1 PID INTEGRIN3 PATHWAY Beta3 integrin cell surface interactions
0.0 0.0 PID TRAIL PATHWAY TRAIL signaling pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 REACTOME SOS MEDIATED SIGNALLING Genes involved in SOS-mediated signalling
0.0 0.0 REACTOME DOWNSTREAM SIGNALING EVENTS OF B CELL RECEPTOR BCR Genes involved in Downstream Signaling Events Of B Cell Receptor (BCR)
0.0 0.4 REACTOME DCC MEDIATED ATTRACTIVE SIGNALING Genes involved in DCC mediated attractive signaling
0.0 0.0 REACTOME ACYL CHAIN REMODELLING OF PC Genes involved in Acyl chain remodelling of PC
0.0 0.3 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.0 0.2 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.0 0.6 REACTOME MYOGENESIS Genes involved in Myogenesis
0.0 0.0 REACTOME ENDOGENOUS STEROLS Genes involved in Endogenous sterols
0.0 0.0 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION Genes involved in TRAF6 mediated IRF7 activation
0.0 0.1 REACTOME ROLE OF SECOND MESSENGERS IN NETRIN1 SIGNALING Genes involved in Role of second messengers in netrin-1 signaling
0.0 0.2 REACTOME TRAF6 MEDIATED INDUCTION OF TAK1 COMPLEX Genes involved in TRAF6 mediated induction of TAK1 complex
0.0 0.1 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
0.0 0.2 REACTOME PRE NOTCH PROCESSING IN GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.0 0.3 REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.0 0.2 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0 0.0 REACTOME SIGNALING BY CONSTITUTIVELY ACTIVE EGFR Genes involved in Signaling by constitutively active EGFR
0.0 0.0 REACTOME DOWNSTREAM TCR SIGNALING Genes involved in Downstream TCR signaling
0.0 0.3 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.0 0.1 REACTOME PURINE CATABOLISM Genes involved in Purine catabolism
0.0 0.1 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.0 0.1 REACTOME CREATION OF C4 AND C2 ACTIVATORS Genes involved in Creation of C4 and C2 activators
0.0 0.0 REACTOME PLATELET SENSITIZATION BY LDL Genes involved in Platelet sensitization by LDL
0.0 0.1 REACTOME NEPHRIN INTERACTIONS Genes involved in Nephrin interactions
0.0 0.2 REACTOME REGULATION OF INSULIN SECRETION BY GLUCAGON LIKE PEPTIDE1 Genes involved in Regulation of Insulin Secretion by Glucagon-like Peptide-1
0.0 0.0 REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.0 0.1 REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the early endosome membrane
0.0 0.1 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
0.0 0.1 REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.0 0.1 REACTOME REGULATED PROTEOLYSIS OF P75NTR Genes involved in Regulated proteolysis of p75NTR
0.0 0.1 REACTOME GLYCOLYSIS Genes involved in Glycolysis