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ENCODE: H3K4me1 ChIP-Seq of primary human cells
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Results for RXRG

Z-value: 0.82

Motif logo

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Transcription factors associated with RXRG

Gene Symbol Gene ID Gene Info
RXRG
ENSG00000143171.8 retinoid X receptor gamma

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE Gene Distance Association probability Pearson corr. coef. P-value Plot
chr1_165393859_165394115RXRG204460.2123680.713.0e-02Click!
chr1_165393302_165393453RXRG210560.2108580.665.5e-02Click!
chr1_165414517_165414668RXRG1590.966147-0.481.9e-01Click!
chr1_165414132_165414400RXRG1670.964415-0.255.1e-01Click!
chr1_165394165_165394316RXRG201930.2129890.206.0e-01Click!

Activity of the RXRG motif across conditions

Conditions sorted by the z-value of the RXRG motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE) Target Score Top associated gene Gene Info Distance of CRE to TSS CRE/Gene association probability
chr22_50360662_50360813 0.48 PIM3
 pim-3 oncogene
 6576
 0.19
chr19_51627416_51627752 0.36 SIGLEC9
 sialic acid binding Ig-like lectin 9
 581
 0.56
chr5_133457481_133458118 0.34 TCF7
 transcription factor 7 (T-cell specific, HMG-box)
 1510
 0.45
chr11_67173722_67173982 0.29 TBC1D10C
 TBC1 domain family, member 10C
 2192
 0.12
chr10_72083897_72084209 0.28 NPFFR1
 neuropeptide FF receptor 1
 40621
 0.14
chr19_5952060_5952229 0.27 RANBP3
 RAN binding protein 3
 25946
 0.08
chr8_130696046_130696267 0.27 GSDMC
 gasdermin C
 102978
 0.06
chr17_81011696_81011877 0.26 B3GNTL1
 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase-like 1
 2100
 0.35
chr1_77513564_77513779 0.26 RP4-564M11.2
19934
 0.23
chr5_169695577_169695892 0.25 LCP2
 lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa)
 1403
 0.48
chr17_45779984_45780199 0.25 TBKBP1
 TBK1 binding protein 1
 7461
 0.14
chr4_2418867_2419018 0.25 ZFYVE28
 zinc finger, FYVE domain containing 28
 1394
 0.4
chr6_167460456_167460849 0.25 FGFR1OP
 FGFR1 oncogene partner
 47756
 0.1
chr19_42382114_42382373 0.25 CD79A
 CD79a molecule, immunoglobulin-associated alpha
 868
 0.44
chr2_43439781_43440131 0.24 ZFP36L2
 ZFP36 ring finger protein-like 2
 13792
 0.22
chr14_69290800_69290951 0.24 ENSG00000263694
 .
 21644
 0.18
chr19_7607962_7608247 0.24 PNPLA6
 patatin-like phospholipase domain containing 6
 3180
 0.13
chr20_47401167_47401399 0.24 PREX1
 phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 1
 43137
 0.17
chr8_87355273_87355424 0.23 WWP1
 WW domain containing E3 ubiquitin protein ligase 1
 381
 0.91
chr5_543677_544187 0.23 ENSG00000264233
 .
 7935
 0.14
chr2_8618267_8618671 0.23 AC011747.7
197427
 0.03
chr3_44558841_44559128 0.22 ENSG00000264774
 .
 2191
 0.23
chr11_47416662_47417076 0.22 RP11-750H9.5
322
 0.77
chr19_7795290_7795492 0.22 CLEC4G
 C-type lectin domain family 4, member G
 1666
 0.22
chr17_81010368_81010641 0.22 B3GNTL1
 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase-like 1
 818
 0.67
chr11_64257656_64257906 0.22 AP003774.4
 HCG1652096, isoform CRA_a; Uncharacterized protein; cDNA FLJ37045 fis, clone BRACE2012185
 41235
 0.11
chr6_110796846_110797132 0.22 SLC22A16
 solute carrier family 22 (organic cation/carnitine transporter), member 16
 610
 0.69
chr19_13205558_13205827 0.21 LYL1
 lymphoblastic leukemia derived sequence 1
 7989
 0.1
chr19_13212572_13212806 0.21 LYL1
 lymphoblastic leukemia derived sequence 1
 992
 0.37
chr6_37924307_37924458 0.21 ZFAND3
 zinc finger, AN1-type domain 3
 26647
 0.2
chr17_55485159_55485393 0.21 ENSG00000263902
 .
 4286
 0.31
chr20_2731303_2731547 0.21 EBF4
 early B-cell factor 4
 44538
 0.08
chr12_113531682_113531833 0.21 DTX1
 deltex homolog 1 (Drosophila)
 36262
 0.1
chr9_92723584_92723735 0.21 ENSG00000263967
 .
 62158
 0.16
chr5_55984183_55984556 0.21 AC022431.2
 Homo sapiens uncharacterized LOC101928448 (LOC101928448), mRNA.
 82310
 0.09
chr14_104928302_104928602 0.20 ENSG00000222761
 .
 61067
 0.12
chr4_1237782_1238175 0.20 CTBP1
 C-terminal binding protein 1
 2267
 0.22
chr1_151025492_151025717 0.20 MLLT11
 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
 4630
 0.09
chr17_78756379_78756543 0.20 RP11-28G8.1
22971
 0.22
chr7_143060122_143060387 0.20 FAM131B
 family with sequence similarity 131, member B
 409
 0.74
chr11_64492185_64492449 0.20 NRXN2
 neurexin 2
 1657
 0.28
chr1_230322984_230323135 0.20 RP5-956O18.2
81170
 0.09
chr3_195529321_195529533 0.20 MUC4
 mucin 4, cell surface associated
 9301
 0.2
chr1_845118_845307 0.20 SAMD11
 sterile alpha motif domain containing 11
 15048
 0.11
chr9_92096814_92097125 0.19 SEMA4D
 sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D
 2164
 0.36
chr1_156251979_156252130 0.19 SMG5
 SMG5 nonsense mediated mRNA decay factor
 562
 0.43
chr2_10677292_10677443 0.19 AC092687.5
51925
 0.13
chr3_52325077_52325228 0.19 GLYCTK
 glycerate kinase
 822
 0.39
chr10_129718614_129719007 0.19 PTPRE
 protein tyrosine phosphatase, receptor type, E
 13394
 0.2
chr4_6945535_6945709 0.19 ENSG00000265953
 .
 9394
 0.15
chr7_100798039_100798250 0.19 AP1S1
 adaptor-related protein complex 1, sigma 1 subunit
 338
 0.77
chr17_37796865_37797043 0.19 STARD3
 StAR-related lipid transfer (START) domain containing 3
 3331
 0.14
chr15_81586884_81587161 0.19 IL16
 interleukin 16
 2232
 0.32
chr17_76253152_76253544 0.19 TMEM235
 transmembrane protein 235
 25226
 0.12
chr16_23869581_23869825 0.19 PRKCB
 protein kinase C, beta
 21159
 0.22
chr15_67358635_67358896 0.19 SMAD3
 SMAD family member 3
 582
 0.84
chr14_102818626_102818777 0.19 ENSG00000239061
 .
 6538
 0.13
chrX_128920075_128920364 0.18 SASH3
 SAM and SH3 domain containing 3
 6259
 0.21
chr12_1906232_1906409 0.18 CACNA2D4
 calcium channel, voltage-dependent, alpha 2/delta subunit 4
 14566
 0.2
chr12_12013969_12014120 0.18 ETV6
 ets variant 6
 24827
 0.26
chr20_4795714_4796665 0.18 RASSF2
 Ras association (RalGDS/AF-6) domain family member 2
 420
 0.85
chr11_85912300_85912516 0.18 EED
 embryonic ectoderm development
 43178
 0.14
chr18_55710965_55711289 0.18 NEDD4L
 neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase
 472
 0.86
chr19_8676750_8676918 0.18 ADAMTS10
 ADAM metallopeptidase with thrombospondin type 1 motif, 10
 1249
 0.4
chr15_75337787_75338089 0.18 PPCDC
 phosphopantothenoylcysteine decarboxylase
 2322
 0.25
chr19_1471924_1472075 0.18 C19orf25
 chromosome 19 open reading frame 25
 6897
 0.07
chr1_155936937_155937092 0.18 ARHGEF2
 Rho/Rac guanine nucleotide exchange factor (GEF) 2
 2506
 0.14
chr1_68151351_68151556 0.18 GADD45A
 growth arrest and DNA-damage-inducible, alpha
 569
 0.8
chr10_73127227_73127403 0.18 CDH23
 cadherin-related 23
 29376
 0.17
chr6_157160099_157160284 0.18 RP11-230C9.3
58602
 0.13
chr10_104517058_104517275 0.18 WBP1L
 WW domain binding protein 1-like
 13439
 0.14
chr11_328111_328341 0.17 IFITM3
 interferon induced transmembrane protein 3
 689
 0.43
chr17_79420586_79420890 0.17 ENSG00000266189
 .
 2524
 0.16
chr7_50247596_50247947 0.17 AC020743.2
65352
 0.12
chr12_111216861_111217180 0.17 PPP1CC
 protein phosphatase 1, catalytic subunit, gamma isozyme
 36276
 0.16
chr1_109642870_109643021 0.17 ENSG00000270066
 .
 130
 0.93
chr11_2468048_2468289 0.17 KCNQ1
 potassium voltage-gated channel, KQT-like subfamily, member 1
 1947
 0.26
chr1_36945879_36946111 0.17 CSF3R
 colony stimulating factor 3 receptor (granulocyte)
 898
 0.54
chr17_37618451_37618639 0.17 CDK12
 cyclin-dependent kinase 12
 253
 0.9
chr21_46902705_46902925 0.17 COL18A1
 collagen, type XVIII, alpha 1
 7374
 0.21
chr4_54569449_54569737 0.17 LNX1
 ligand of numb-protein X 1, E3 ubiquitin protein ligase
 2021
 0.37
chr6_91004978_91005129 0.17 BACH2
 BTB and CNC homology 1, basic leucine zipper transcription factor 2
 1408
 0.5
chr2_62430640_62430961 0.17 ENSG00000266097
 .
 2161
 0.29
chr19_49920997_49921157 0.17 PTH2
 parathyroid hormone 2
 5621
 0.07
chr17_32964273_32964569 0.17 TMEM132E
 transmembrane protein 132E
 56653
 0.13
chr19_7402652_7402854 0.17 CTB-133G6.1
11095
 0.16
chr1_12200334_12200485 0.17 TNFRSF8
 tumor necrosis factor receptor superfamily, member 8
 14453
 0.15
chr2_231527868_231528072 0.17 CAB39
 calcium binding protein 39
 49590
 0.13
chr3_188010595_188010746 0.17 LPP
 LIM domain containing preferred translocation partner in lipoma
 53018
 0.17
chr19_41224754_41224952 0.17 ADCK4
 aarF domain containing kinase 4
 741
 0.46
chr12_96599777_96599928 0.17 ELK3
 ELK3, ETS-domain protein (SRF accessory protein 2)
 11460
 0.2
chr17_7240555_7240902 0.17 ACAP1
 ArfGAP with coiled-coil, ankyrin repeat and PH domains 1
 819
 0.31
chr9_120588985_120589386 0.17 ENSG00000251847
 .
 95436
 0.08
chr7_962089_962318 0.17 ADAP1
 ArfGAP with dual PH domains 1
 1677
 0.3
chr6_161621899_161622078 0.17 AGPAT4
 1-acylglycerol-3-phosphate O-acyltransferase 4
 51667
 0.18
chr17_42392949_42393100 0.17 AC003102.3
341
 0.73
chr17_38720722_38720873 0.17 CCR7
 chemokine (C-C motif) receptor 7
 914
 0.56
chr1_160617137_160617535 0.17 SLAMF1
 signaling lymphocytic activation molecule family member 1
 251
 0.91
chr3_111838750_111839161 0.17 ENSG00000207940
 .
 7307
 0.16
chr17_9924432_9924619 0.17 GAS7
 growth arrest-specific 7
 1066
 0.59
chr19_16228343_16228511 0.16 RAB8A
 RAB8A, member RAS oncogene family
 5720
 0.14
chr17_45911855_45912006 0.16 LRRC46
 leucine rich repeat containing 46
 2937
 0.14
chr11_64401610_64401843 0.16 NRXN2
 neurexin 2
 8432
 0.15
chr16_17568308_17568782 0.16 XYLT1
 xylosyltransferase I
 3807
 0.39
chr17_71736626_71736794 0.16 SDK2
 sidekick cell adhesion molecule 2
 96482
 0.08
chr11_64568441_64568592 0.16 MAP4K2
 mitogen-activated protein kinase kinase kinase kinase 2
 2131
 0.19
chr15_92023442_92023593 0.16 SV2B
 synaptic vesicle glycoprotein 2B
 254417
 0.02
chr2_220075581_220075882 0.16 ZFAND2B
 zinc finger, AN1-type domain 2B
 2551
 0.11
chr11_63305751_63305902 0.16 RARRES3
 retinoic acid receptor responder (tazarotene induced) 3
 42
 0.97
chr19_16395394_16395593 0.16 CTD-2562J15.6
8893
 0.16
chr1_9797259_9797436 0.16 CLSTN1
 calsyntenin 1
 14292
 0.17
chr12_69166647_69166888 0.16 AC124890.1
 HCG1774533, isoform CRA_a; PRO2268; Uncharacterized protein
 19358
 0.14
chr19_50063674_50064142 0.16 NOSIP
 nitric oxide synthase interacting protein
 21
 0.93
chr11_44117733_44117933 0.16 EXT2
 exostosin glycosyltransferase 2
 60
 0.97
chr19_13067455_13067695 0.16 GADD45GIP1
 growth arrest and DNA-damage-inducible, gamma interacting protein 1
 475
 0.54
chr2_46502581_46502732 0.16 EPAS1
 endothelial PAS domain protein 1
 21091
 0.24
chr17_79478415_79478566 0.16 ENSG00000266077
 .
 355
 0.7
chr19_3671752_3672026 0.16 AC004637.1
691
 0.55
chr14_102063212_102063453 0.16 DIO3
 deiodinase, iodothyronine, type III
 35644
 0.15
chr2_128242825_128243074 0.16 ENSG00000202429
 .
 13139
 0.14
chr10_100202612_100202763 0.16 HPS1
 Hermansky-Pudlak syndrome 1
 3980
 0.22
chr13_113438175_113438326 0.16 ATP11A
 ATPase, class VI, type 11A
 1236
 0.5
chr19_6767196_6767347 0.16 SH2D3A
 SH2 domain containing 3A
 175
 0.92
chr1_31234795_31234983 0.16 LAPTM5
 lysosomal protein transmembrane 5
 4222
 0.2
chr19_16369309_16369616 0.16 AP1M1
 adaptor-related protein complex 1, mu 1 subunit
 31046
 0.12
chr16_88706951_88707212 0.16 IL17C
 interleukin 17C
 2080
 0.17
chr22_32596610_32596827 0.16 RFPL2
 ret finger protein-like 2
 2746
 0.21
chr1_235096750_235097092 0.16 ENSG00000239690
 .
 56988
 0.14
chr18_2848147_2848503 0.16 EMILIN2
 elastin microfibril interfacer 2
 1297
 0.4
chr2_110962298_110962466 0.16 NPHP1
 nephronophthisis 1 (juvenile)
 167
 0.96
chr15_81616223_81616414 0.16 STARD5
 StAR-related lipid transfer (START) domain containing 5
 148
 0.78
chr16_79308560_79308711 0.16 ENSG00000222244
 .
 10284
 0.3
chr6_90984611_90985132 0.16 BACH2
 BTB and CNC homology 1, basic leucine zipper transcription factor 2
 21590
 0.23
chr7_73117969_73118147 0.16 ENSG00000265724
 .
 7589
 0.1
chr11_4004733_4004995 0.16 STIM1
 stromal interaction molecule 1
 36291
 0.14
chr7_127292633_127293077 0.16 SND1
 staphylococcal nuclease and tudor domain containing 1
 621
 0.5
chr2_38512547_38512698 0.16 ATL2
 atlastin GTPase 2
 90744
 0.08
chr3_38415523_38415797 0.16 XYLB
 xylulokinase homolog (H. influenzae)
 27314
 0.16
chr17_7747631_7748159 0.16 KDM6B
 lysine (K)-specific demethylase 6B
 338
 0.77
chr19_15385020_15385239 0.16 BRD4
 bromodomain containing 4
 6133
 0.19
chr15_78395791_78396151 0.16 SH2D7
 SH2 domain containing 7
 11044
 0.13
chr15_55549033_55549184 0.16 RAB27A
 RAB27A, member RAS oncogene family
 7875
 0.22
chrX_48973868_48974136 0.16 GPKOW
 G patch domain and KOW motifs
 6149
 0.09
chr17_74268830_74269044 0.16 UBALD2
 UBA-like domain containing 2
 7153
 0.13
chr16_27410389_27410773 0.15 IL21R
 interleukin 21 receptor
 2902
 0.28
chr14_102664211_102664362 0.15 WDR20
 WD repeat domain 20
 3003
 0.26
chr15_91380724_91380980 0.15 CTD-3094K11.1
2102
 0.22
chr8_134079341_134079492 0.15 SLA
 Src-like-adaptor
 6813
 0.26
chr14_101875137_101875288 0.15 ENSG00000258498
 .
 151547
 0.02
chr17_19037709_19038128 0.15 GRAPL
 GRB2-related adaptor protein-like
 1886
 0.17
chr8_68881201_68881427 0.15 PREX2
 phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2
 16961
 0.28
chr1_15650780_15650931 0.15 RP3-467K16.7
11105
 0.16
chr20_32030445_32030661 0.15 SNTA1
 syntrophin, alpha 1
 1145
 0.46
chr13_40533809_40533960 0.15 ENSG00000212553
 .
 102520
 0.08
chr6_35277451_35277713 0.15 DEF6
 differentially expressed in FDCP 6 homolog (mouse)
 67
 0.97
chrX_129306523_129306726 0.15 RAB33A
 RAB33A, member RAS oncogene family
 1001
 0.56
chr22_35729612_35729777 0.15 ENSG00000266320
 .
 1939
 0.29
chr1_161015258_161015409 0.15 USF1
 upstream transcription factor 1
 330
 0.76
chr5_75637588_75637859 0.15 RP11-466P24.6
30436
 0.21
chr22_30679087_30679350 0.15 GATSL3
 GATS protein-like 3
 6378
 0.1
chr11_67050388_67050683 0.15 ANKRD13D
 ankyrin repeat domain 13 family, member D
 5483
 0.12
chr14_93203173_93203394 0.15 LGMN
 legumain
 11632
 0.25
chr15_63570030_63570181 0.15 APH1B
 APH1B gamma secretase subunit
 288
 0.93
chr5_139928576_139928727 0.15 EIF4EBP3
 eukaryotic translation initiation factor 4E binding protein 3
 1400
 0.21
chr1_223351560_223351778 0.15 TLR5
 toll-like receptor 5
 35045
 0.22
chrX_135865687_135865855 0.15 ARHGEF6
 Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6
 1524
 0.38
chr19_18980510_18980983 0.15 AC005197.2
11743
 0.11
chr7_30068456_30068607 0.15 PLEKHA8
 pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 8
 230
 0.9
chr1_9305121_9305314 0.15 H6PD
 hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase)
 5314
 0.21
chrX_48792186_48792645 0.15 PIM2
 pim-2 oncogene
 16114
 0.08
chr3_111032298_111032588 0.15 CD96
 CD96 molecule
 20877
 0.27
chr10_14577268_14577434 0.15 FAM107B
 family with sequence similarity 107, member B
 2642
 0.34
chrX_2747833_2747984 0.15 GYG2
 glycogenin 2
 595
 0.71
chr1_54764314_54764483 0.15 RP5-997D24.3
13320
 0.18
chr17_18943047_18943488 0.15 GRAP
 GRB2-related adaptor protein
 2531
 0.17
chr7_150132614_150132825 0.15 GIMAP8
 GTPase, IMAP family member 8
 14999
 0.15
chr17_7035953_7036156 0.15 ASGR2
 asialoglycoprotein receptor 2
 17035
 0.1
chr14_89825766_89826160 0.15 RP11-356K23.2
4559
 0.2
chr3_18768057_18768243 0.15 ENSG00000228956
 .
 19086
 0.29
chr2_238649424_238649774 0.15 LRRFIP1
 leucine rich repeat (in FLII) interacting protein 1
 48617
 0.13
chr3_52880668_52880966 0.15 TMEM110-MUSTN1
 TMEM110-MUSTN1 readthrough
 3854
 0.13
chr17_4881765_4881941 0.15 RP5-1050D4.2
5707
 0.06
chr9_36150617_36150840 0.15 GLIPR2
 GLI pathogenesis-related 2
 13986
 0.17
chr1_22788372_22788560 0.15 ZBTB40
 zinc finger and BTB domain containing 40
 9994
 0.23
chr14_23495394_23495545 0.15 ENSG00000207765
 .
 7378
 0.08
chr1_161160490_161160641 0.15 ADAMTS4
 ADAM metallopeptidase with thrombospondin type 1 motif, 4
 8278
 0.06
chr6_159540709_159540860 0.14 RP11-13P5.2
47601
 0.13
chr17_72984009_72984428 0.14 CDR2L
 cerebellar degeneration-related protein 2-like
 491
 0.63
chr2_19560748_19560899 0.14 OSR1
 odd-skipped related transciption factor 1
 2409
 0.37
chr22_24828899_24829111 0.14 ADORA2A
 adenosine A2a receptor
 197
 0.94
chr2_239068958_239069217 0.14 FAM132B
 family with sequence similarity 132, member B
 1438
 0.32
chr2_113993602_113993853 0.14 ENSG00000189223
 .
 87
 0.91
chr9_136925319_136925470 0.14 BRD3
 bromodomain containing 3
 4260
 0.19
chr10_73830371_73830560 0.14 SPOCK2
 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2
 17621
 0.22
chr6_2516451_2516602 0.14 ENSG00000266252
 .
 106657
 0.07
chr5_150600157_150600636 0.14 CCDC69
 coiled-coil domain containing 69
 3310
 0.24
chr2_113944916_113945243 0.14 PSD4
 pleckstrin and Sec7 domain containing 4
 8778
 0.14
chr16_50728117_50728492 0.14 NOD2
 nucleotide-binding oligomerization domain containing 2
 767
 0.52
chr19_39616574_39617021 0.14 PAK4
 p21 protein (Cdc42/Rac)-activated kinase 4
 323
 0.84
chr1_226839780_226839931 0.14 ITPKB-IT1
 ITPKB intronic transcript 1 (non-protein coding)
 7516
 0.22

Histogram of CRE-TSS distances for CREs targeted by :

Histogram of

Rank distribution of CRE target scores:

Histogram of target CRE score.

Distribution of target CREs across different genomic regions:

Weighted Piechart of Weighted Piechart of Weighted Piechart of

Network of associatons between targets according to the STRING database.

First level regulatory network of RXRG

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.1 GO:0002448 mast cell mediated immunity(GO:0002448)
0.1 0.2 GO:0014056 acetylcholine secretion, neurotransmission(GO:0014055) regulation of acetylcholine secretion, neurotransmission(GO:0014056) acetylcholine secretion(GO:0061526)
0.1 0.2 GO:0015014 heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.1 0.2 GO:0030223 neutrophil differentiation(GO:0030223)
0.1 0.2 GO:0006883 cellular sodium ion homeostasis(GO:0006883)
0.1 0.2 GO:0035405 histone-threonine phosphorylation(GO:0035405)
0.0 0.1 GO:0016242 negative regulation of macroautophagy(GO:0016242)
0.0 0.1 GO:0019049 evasion or tolerance of host defenses by virus(GO:0019049) avoidance of host defenses(GO:0044413) evasion or tolerance of host defenses(GO:0044415) avoidance of defenses of other organism involved in symbiotic interaction(GO:0051832) evasion or tolerance of defenses of other organism involved in symbiotic interaction(GO:0051834)
0.0 0.1 GO:0045990 carbon catabolite regulation of transcription(GO:0045990) regulation of transcription by glucose(GO:0046015)
0.0 0.1 GO:0006651 diacylglycerol biosynthetic process(GO:0006651)
0.0 0.1 GO:0001865 NK T cell differentiation(GO:0001865) regulation of NK T cell differentiation(GO:0051136) positive regulation of NK T cell differentiation(GO:0051138)
0.0 0.1 GO:0072239 metanephric glomerulus development(GO:0072224) metanephric glomerulus vasculature development(GO:0072239)
0.0 0.2 GO:0070670 response to interleukin-4(GO:0070670)
0.0 0.1 GO:0015917 aminophospholipid transport(GO:0015917)
0.0 0.0 GO:0002513 tolerance induction to self antigen(GO:0002513)
0.0 0.1 GO:0045943 positive regulation of transcription from RNA polymerase I promoter(GO:0045943)
0.0 0.1 GO:0043320 natural killer cell activation involved in immune response(GO:0002323) natural killer cell degranulation(GO:0043320)
0.0 0.1 GO:0010572 positive regulation of platelet activation(GO:0010572)
0.0 0.1 GO:0048548 regulation of pinocytosis(GO:0048548)
0.0 0.1 GO:0032020 ISG15-protein conjugation(GO:0032020)
0.0 0.1 GO:0031061 negative regulation of histone methylation(GO:0031061)
0.0 0.1 GO:0052169 pathogen-associated molecular pattern dependent induction by symbiont of host innate immune response(GO:0052033) positive regulation by symbiont of host innate immune response(GO:0052166) modulation by symbiont of host innate immune response(GO:0052167) pathogen-associated molecular pattern dependent modulation by symbiont of host innate immune response(GO:0052169) pathogen-associated molecular pattern dependent induction by organism of innate immune response of other organism involved in symbiotic interaction(GO:0052257) positive regulation by organism of innate immune response in other organism involved in symbiotic interaction(GO:0052305) modulation by organism of innate immune response in other organism involved in symbiotic interaction(GO:0052306) pathogen-associated molecular pattern dependent modulation by organism of innate immune response in other organism involved in symbiotic interaction(GO:0052308)
0.0 0.1 GO:0046501 protoporphyrinogen IX metabolic process(GO:0046501)
0.0 0.1 GO:1901534 positive regulation of megakaryocyte differentiation(GO:0045654) positive regulation of hematopoietic progenitor cell differentiation(GO:1901534)
0.0 0.0 GO:0002888 positive regulation of myeloid leukocyte mediated immunity(GO:0002888)
0.0 0.1 GO:0007500 mesodermal cell fate determination(GO:0007500)
0.0 0.1 GO:0001778 plasma membrane repair(GO:0001778)
0.0 0.1 GO:0001911 negative regulation of leukocyte mediated cytotoxicity(GO:0001911)
0.0 0.1 GO:0002227 innate immune response in mucosa(GO:0002227) mucosal immune response(GO:0002385)
0.0 0.0 GO:0060242 contact inhibition(GO:0060242)
0.0 0.1 GO:0007195 adenylate cyclase-inhibiting dopamine receptor signaling pathway(GO:0007195)
0.0 0.1 GO:0045349 interferon-alpha biosynthetic process(GO:0045349) regulation of interferon-alpha biosynthetic process(GO:0045354)
0.0 0.1 GO:0034501 protein localization to kinetochore(GO:0034501)
0.0 0.1 GO:0042732 D-xylose metabolic process(GO:0042732)
0.0 0.1 GO:0070874 negative regulation of glycogen metabolic process(GO:0070874)
0.0 0.1 GO:0060391 positive regulation of SMAD protein import into nucleus(GO:0060391)
0.0 0.1 GO:0045722 positive regulation of gluconeogenesis(GO:0045722)
0.0 0.1 GO:0045056 transcytosis(GO:0045056)
0.0 0.1 GO:0046968 peptide antigen transport(GO:0046968)
0.0 0.1 GO:0006689 ganglioside catabolic process(GO:0006689)
0.0 0.1 GO:0009051 pentose-phosphate shunt, oxidative branch(GO:0009051)
0.0 0.0 GO:0003197 endocardial cushion development(GO:0003197)
0.0 0.0 GO:0033004 negative regulation of mast cell activation(GO:0033004)
0.0 0.1 GO:0032914 positive regulation of transforming growth factor beta1 production(GO:0032914)
0.0 0.3 GO:0032011 ARF protein signal transduction(GO:0032011)
0.0 0.0 GO:0032415 regulation of sodium:proton antiporter activity(GO:0032415) regulation of sodium ion transmembrane transport(GO:1902305) regulation of sodium ion transmembrane transporter activity(GO:2000649)
0.0 0.1 GO:0051001 negative regulation of nitric-oxide synthase activity(GO:0051001)
0.0 0.0 GO:2001012 mesenchymal cell differentiation involved in kidney development(GO:0072161) metanephric mesenchymal cell differentiation(GO:0072162) mesenchymal cell differentiation involved in renal system development(GO:2001012)
0.0 0.3 GO:0071479 cellular response to ionizing radiation(GO:0071479)
0.0 0.0 GO:1903429 regulation of neuron maturation(GO:0014041) regulation of cell maturation(GO:1903429)
0.0 0.1 GO:0046322 negative regulation of fatty acid oxidation(GO:0046322)
0.0 0.1 GO:0009186 deoxyribonucleoside diphosphate metabolic process(GO:0009186)
0.0 0.1 GO:0090281 negative regulation of calcium ion import(GO:0090281)
0.0 0.0 GO:0046101 hypoxanthine biosynthetic process(GO:0046101)
0.0 0.1 GO:0090073 positive regulation of protein homodimerization activity(GO:0090073)
0.0 0.1 GO:0006154 adenosine catabolic process(GO:0006154)
0.0 0.1 GO:0003181 atrioventricular valve development(GO:0003171) atrioventricular valve morphogenesis(GO:0003181)
0.0 0.1 GO:0042761 very long-chain fatty acid biosynthetic process(GO:0042761)
0.0 0.0 GO:0030210 heparin metabolic process(GO:0030202) heparin biosynthetic process(GO:0030210)
0.0 0.1 GO:0045059 positive thymic T cell selection(GO:0045059)
0.0 0.2 GO:0015695 organic cation transport(GO:0015695)
0.0 0.1 GO:0018094 protein polyglycylation(GO:0018094)
0.0 0.1 GO:0043615 astrocyte cell migration(GO:0043615)
0.0 0.1 GO:0006198 cAMP catabolic process(GO:0006198)
0.0 0.0 GO:0045603 positive regulation of endothelial cell differentiation(GO:0045603)
0.0 0.0 GO:0010523 negative regulation of calcium ion transport into cytosol(GO:0010523)
0.0 0.2 GO:0045648 positive regulation of erythrocyte differentiation(GO:0045648)
0.0 0.0 GO:0051712 positive regulation of killing of cells of other organism(GO:0051712)
0.0 0.1 GO:0060080 inhibitory postsynaptic potential(GO:0060080)
0.0 0.0 GO:0048807 female genitalia morphogenesis(GO:0048807)
0.0 0.1 GO:0006002 fructose 6-phosphate metabolic process(GO:0006002)
0.0 0.0 GO:0018076 N-terminal peptidyl-lysine acetylation(GO:0018076)
0.0 0.0 GO:0060235 lens induction in camera-type eye(GO:0060235)
0.0 0.0 GO:0002478 antigen processing and presentation of exogenous peptide antigen(GO:0002478)
0.0 0.1 GO:0006600 creatine metabolic process(GO:0006600)
0.0 0.1 GO:0032957 inositol trisphosphate metabolic process(GO:0032957)
0.0 0.0 GO:0033629 negative regulation of cell adhesion mediated by integrin(GO:0033629)
0.0 0.1 GO:0001955 blood vessel maturation(GO:0001955)
0.0 0.0 GO:0045343 MHC class I biosynthetic process(GO:0045341) regulation of MHC class I biosynthetic process(GO:0045343)
0.0 0.1 GO:0045577 regulation of B cell differentiation(GO:0045577)
0.0 0.1 GO:0043049 otic placode formation(GO:0043049)
0.0 0.0 GO:0046931 pore complex assembly(GO:0046931)
0.0 0.1 GO:0002726 positive regulation of T cell cytokine production(GO:0002726)
0.0 0.1 GO:0046718 viral entry into host cell(GO:0046718)
0.0 0.0 GO:0090218 positive regulation of phosphatidylinositol 3-kinase activity(GO:0043552) positive regulation of lipid kinase activity(GO:0090218)
0.0 0.0 GO:0002085 inhibition of neuroepithelial cell differentiation(GO:0002085)
0.0 0.0 GO:0043951 negative regulation of cAMP-mediated signaling(GO:0043951)
0.0 0.0 GO:0014874 response to stimulus involved in regulation of muscle adaptation(GO:0014874)
0.0 0.0 GO:0055078 sodium ion homeostasis(GO:0055078)
0.0 0.0 GO:0006106 fumarate metabolic process(GO:0006106)
0.0 0.2 GO:0006349 regulation of gene expression by genetic imprinting(GO:0006349)
0.0 0.1 GO:0007210 serotonin receptor signaling pathway(GO:0007210)
0.0 0.1 GO:0042535 positive regulation of tumor necrosis factor biosynthetic process(GO:0042535)
0.0 0.1 GO:0006003 fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.0 0.0 GO:0051590 positive regulation of neurotransmitter transport(GO:0051590)
0.0 0.1 GO:0031282 regulation of guanylate cyclase activity(GO:0031282)
0.0 0.0 GO:0046668 regulation of retinal cell programmed cell death(GO:0046668)
0.0 0.0 GO:0002125 maternal aggressive behavior(GO:0002125)
0.0 0.0 GO:0055075 potassium ion homeostasis(GO:0055075)
0.0 0.1 GO:0090286 cytoskeletal anchoring at nuclear membrane(GO:0090286)
0.0 0.0 GO:0033688 regulation of osteoblast proliferation(GO:0033688)
0.0 0.0 GO:0002679 respiratory burst involved in defense response(GO:0002679)
0.0 0.0 GO:0045162 clustering of voltage-gated sodium channels(GO:0045162)
0.0 0.1 GO:0042354 fucose catabolic process(GO:0019317) L-fucose metabolic process(GO:0042354) L-fucose catabolic process(GO:0042355)
0.0 0.0 GO:0071921 establishment of sister chromatid cohesion(GO:0034085) cohesin loading(GO:0071921) regulation of cohesin loading(GO:0071922)
0.0 0.1 GO:0007023 post-chaperonin tubulin folding pathway(GO:0007023)
0.0 0.1 GO:0006700 C21-steroid hormone biosynthetic process(GO:0006700)
0.0 0.0 GO:0006189 'de novo' IMP biosynthetic process(GO:0006189)
0.0 0.1 GO:0010508 positive regulation of autophagy(GO:0010508)
0.0 0.1 GO:0051491 positive regulation of filopodium assembly(GO:0051491)
0.0 0.1 GO:0042989 sequestering of actin monomers(GO:0042989)
0.0 0.0 GO:0009415 response to water deprivation(GO:0009414) response to water(GO:0009415)
0.0 0.1 GO:0043388 positive regulation of DNA binding(GO:0043388)
0.0 0.0 GO:0046881 positive regulation of gonadotropin secretion(GO:0032278) positive regulation of follicle-stimulating hormone secretion(GO:0046881)
0.0 0.0 GO:0002282 microglial cell activation involved in immune response(GO:0002282)
0.0 0.1 GO:0022617 extracellular matrix disassembly(GO:0022617)
0.0 0.1 GO:0031274 pseudopodium assembly(GO:0031269) regulation of pseudopodium assembly(GO:0031272) positive regulation of pseudopodium assembly(GO:0031274)
0.0 0.0 GO:0010966 regulation of phosphate transport(GO:0010966)
0.0 0.1 GO:0050930 induction of positive chemotaxis(GO:0050930)
0.0 0.0 GO:0044650 virion attachment to host cell(GO:0019062) adhesion of symbiont to host cell(GO:0044650)
0.0 0.0 GO:0032714 negative regulation of interleukin-5 production(GO:0032714)
0.0 0.0 GO:0060708 spongiotrophoblast differentiation(GO:0060708)
0.0 0.2 GO:0010226 response to lithium ion(GO:0010226)
0.0 0.0 GO:0033152 immunoglobulin V(D)J recombination(GO:0033152)
0.0 0.0 GO:0060218 hematopoietic stem cell differentiation(GO:0060218)
0.0 0.0 GO:0009151 purine deoxyribonucleotide metabolic process(GO:0009151) purine deoxyribonucleoside triphosphate metabolic process(GO:0009215)
0.0 0.2 GO:0045576 mast cell activation(GO:0045576)
0.0 0.0 GO:0006434 seryl-tRNA aminoacylation(GO:0006434)
0.0 0.0 GO:0034219 carbohydrate transmembrane transport(GO:0034219)
0.0 0.0 GO:0001574 ganglioside biosynthetic process(GO:0001574)
0.0 0.0 GO:2000095 regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000095)
0.0 0.0 GO:0061687 detoxification of inorganic compound(GO:0061687) stress response to metal ion(GO:0097501)
0.0 0.1 GO:0048679 regulation of axon regeneration(GO:0048679) regulation of neuron projection regeneration(GO:0070570)
0.0 0.0 GO:0042518 negative regulation of tyrosine phosphorylation of Stat3 protein(GO:0042518)
0.0 0.0 GO:0045821 positive regulation of nucleotide catabolic process(GO:0030813) positive regulation of glycolytic process(GO:0045821) positive regulation of nucleoside metabolic process(GO:0045979) positive regulation of cofactor metabolic process(GO:0051194) positive regulation of coenzyme metabolic process(GO:0051197) positive regulation of ATP metabolic process(GO:1903580)
0.0 0.0 GO:0045425 positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process(GO:0045425)
0.0 0.0 GO:0070779 D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
0.0 0.1 GO:0002634 regulation of germinal center formation(GO:0002634)
0.0 0.0 GO:0009299 mRNA transcription(GO:0009299)
0.0 0.0 GO:0070857 regulation of bile acid biosynthetic process(GO:0070857) regulation of bile acid metabolic process(GO:1904251)
0.0 0.3 GO:0050690 regulation of defense response to virus by virus(GO:0050690)
0.0 0.0 GO:0006089 lactate metabolic process(GO:0006089)
0.0 0.0 GO:0032495 response to muramyl dipeptide(GO:0032495)
0.0 0.0 GO:0021860 pyramidal neuron differentiation(GO:0021859) pyramidal neuron development(GO:0021860)
0.0 0.0 GO:0071318 cellular response to ATP(GO:0071318)
0.0 0.1 GO:0006991 response to sterol depletion(GO:0006991)
0.0 0.0 GO:0071392 cellular response to estradiol stimulus(GO:0071392)
0.0 0.0 GO:0014029 neural crest formation(GO:0014029) neural crest cell fate commitment(GO:0014034)
0.0 0.0 GO:0031057 negative regulation of histone modification(GO:0031057)
0.0 0.0 GO:0010614 negative regulation of cardiac muscle hypertrophy(GO:0010614)
0.0 0.1 GO:2000272 negative regulation of receptor activity(GO:2000272)
0.0 0.2 GO:0005980 glycogen catabolic process(GO:0005980)
0.0 0.0 GO:0045650 negative regulation of macrophage differentiation(GO:0045650)
0.0 0.0 GO:0030260 entry into host cell(GO:0030260) entry into host(GO:0044409) entry into cell of other organism involved in symbiotic interaction(GO:0051806) entry into other organism involved in symbiotic interaction(GO:0051828)
0.0 0.0 GO:0060913 cardiac cell fate determination(GO:0060913)
0.0 0.1 GO:0016577 histone demethylation(GO:0016577)
0.0 0.0 GO:0060004 reflex(GO:0060004)
0.0 0.0 GO:0043490 malate-aspartate shuttle(GO:0043490)
0.0 0.0 GO:0002032 desensitization of G-protein coupled receptor protein signaling pathway by arrestin(GO:0002032)
0.0 0.0 GO:0002025 vasodilation by norepinephrine-epinephrine involved in regulation of systemic arterial blood pressure(GO:0002025)
0.0 0.0 GO:0031536 positive regulation of exit from mitosis(GO:0031536)
0.0 0.0 GO:1903332 regulation of protein folding(GO:1903332)
0.0 0.0 GO:0030854 positive regulation of granulocyte differentiation(GO:0030854)
0.0 0.0 GO:0051451 myoblast migration(GO:0051451)
0.0 0.0 GO:0010739 positive regulation of protein kinase A signaling(GO:0010739)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0070022 transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.0 0.1 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.0 0.2 GO:0001891 phagocytic cup(GO:0001891)
0.0 0.1 GO:0043259 laminin-10 complex(GO:0043259)
0.0 0.2 GO:0098984 asymmetric synapse(GO:0032279) neuron to neuron synapse(GO:0098984)
0.0 0.1 GO:0031088 platelet dense granule membrane(GO:0031088)
0.0 0.2 GO:0042101 T cell receptor complex(GO:0042101)
0.0 0.2 GO:0032391 photoreceptor connecting cilium(GO:0032391)
0.0 0.1 GO:0030121 AP-1 adaptor complex(GO:0030121)
0.0 0.0 GO:0031931 TORC1 complex(GO:0031931)
0.0 0.1 GO:0034045 pre-autophagosomal structure membrane(GO:0034045)
0.0 0.0 GO:0033150 cytoskeletal calyx(GO:0033150)
0.0 0.1 GO:0031362 anchored component of external side of plasma membrane(GO:0031362)
0.0 0.0 GO:0000214 tRNA-intron endonuclease complex(GO:0000214)
0.0 0.1 GO:0090533 cation-transporting ATPase complex(GO:0090533)
0.0 0.1 GO:0034993 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.0 0.0 GO:0032133 chromosome passenger complex(GO:0032133)
0.0 0.0 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
0.0 0.1 GO:0034451 centriolar satellite(GO:0034451)
0.0 0.1 GO:0000300 obsolete peripheral to membrane of membrane fraction(GO:0000300)
0.0 0.1 GO:0005797 Golgi medial cisterna(GO:0005797)
0.0 0.0 GO:0005954 calcium- and calmodulin-dependent protein kinase complex(GO:0005954)
0.0 0.2 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)
0.0 0.1 GO:0019908 nuclear cyclin-dependent protein kinase holoenzyme complex(GO:0019908)
0.0 0.2 GO:0005669 transcription factor TFIID complex(GO:0005669)
0.0 0.0 GO:0005827 polar microtubule(GO:0005827)
0.0 0.0 GO:0005638 lamin filament(GO:0005638)
0.0 0.0 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.0 0.1 GO:0044224 juxtaparanode region of axon(GO:0044224)
0.0 0.1 GO:0072357 PTW/PP1 phosphatase complex(GO:0072357)
0.0 0.1 GO:0008290 F-actin capping protein complex(GO:0008290)
0.0 0.1 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.0 0.1 GO:0000805 X chromosome(GO:0000805)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0005275 amine transmembrane transporter activity(GO:0005275)
0.1 0.2 GO:0004999 vasoactive intestinal polypeptide receptor activity(GO:0004999)
0.1 0.2 GO:0016312 inositol bisphosphate phosphatase activity(GO:0016312)
0.1 0.2 GO:0035184 histone threonine kinase activity(GO:0035184)
0.0 0.2 GO:0004111 creatine kinase activity(GO:0004111)
0.0 0.1 GO:0008474 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.0 0.1 GO:0052834 inositol monophosphate 1-phosphatase activity(GO:0008934) inositol monophosphate phosphatase activity(GO:0052834)
0.0 0.1 GO:0008184 glycogen phosphorylase activity(GO:0008184)
0.0 0.1 GO:0050508 glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0050508)
0.0 0.2 GO:0004706 JUN kinase kinase kinase activity(GO:0004706)
0.0 0.2 GO:0030618 transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity(GO:0030618)
0.0 0.1 GO:0033691 sialic acid binding(GO:0033691)
0.0 0.1 GO:0047238 glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity(GO:0047238)
0.0 0.2 GO:0001609 G-protein coupled adenosine receptor activity(GO:0001609)
0.0 0.1 GO:0003701 obsolete RNA polymerase I transcription factor activity(GO:0003701)
0.0 0.1 GO:0000268 peroxisome targeting sequence binding(GO:0000268)
0.0 0.1 GO:0061731 ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
0.0 0.1 GO:0017089 glycolipid transporter activity(GO:0017089)
0.0 0.2 GO:0050700 CARD domain binding(GO:0050700)
0.0 0.1 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity(GO:0004694)
0.0 0.1 GO:0030023 extracellular matrix constituent conferring elasticity(GO:0030023) structural molecule activity conferring elasticity(GO:0097493)
0.0 0.1 GO:0004616 phosphogluconate dehydrogenase (decarboxylating) activity(GO:0004616)
0.0 0.2 GO:0035251 UDP-glucosyltransferase activity(GO:0035251)
0.0 0.0 GO:0032139 dinucleotide insertion or deletion binding(GO:0032139)
0.0 0.2 GO:0017080 sodium channel regulator activity(GO:0017080)
0.0 0.1 GO:0030368 interleukin-17 receptor activity(GO:0030368)
0.0 0.1 GO:0004911 interleukin-2 receptor activity(GO:0004911)
0.0 0.1 GO:0004465 lipoprotein lipase activity(GO:0004465)
0.0 0.1 GO:0030306 ADP-ribosylation factor binding(GO:0030306)
0.0 0.1 GO:0004117 calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117)
0.0 0.1 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.0 0.1 GO:0004331 fructose-2,6-bisphosphate 2-phosphatase activity(GO:0004331)
0.0 0.2 GO:0016493 C-C chemokine receptor activity(GO:0016493)
0.0 0.1 GO:0004563 beta-N-acetylhexosaminidase activity(GO:0004563)
0.0 0.1 GO:0005025 transforming growth factor beta receptor activity, type I(GO:0005025)
0.0 0.1 GO:0047894 flavonol 3-sulfotransferase activity(GO:0047894)
0.0 0.1 GO:0050431 transforming growth factor beta binding(GO:0050431)
0.0 0.3 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0 0.2 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.0 0.3 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.0 0.1 GO:0004719 protein-L-isoaspartate (D-aspartate) O-methyltransferase activity(GO:0004719)
0.0 0.1 GO:0046920 alpha-(1->3)-fucosyltransferase activity(GO:0046920)
0.0 0.1 GO:0070735 protein-glycine ligase activity(GO:0070735)
0.0 0.0 GO:0005220 inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.0 0.0 GO:0004052 arachidonate 12-lipoxygenase activity(GO:0004052)
0.0 0.0 GO:0043533 inositol 1,3,4,5 tetrakisphosphate binding(GO:0043533)
0.0 0.2 GO:0008353 RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.0 0.1 GO:0031821 G-protein coupled serotonin receptor binding(GO:0031821)
0.0 0.1 GO:0070053 thrombospondin receptor activity(GO:0070053)
0.0 0.0 GO:0045159 myosin II binding(GO:0045159)
0.0 0.1 GO:0008020 G-protein coupled photoreceptor activity(GO:0008020)
0.0 0.0 GO:0004873 asialoglycoprotein receptor activity(GO:0004873)
0.0 0.0 GO:0032137 guanine/thymine mispair binding(GO:0032137)
0.0 0.1 GO:0015421 oligopeptide-transporting ATPase activity(GO:0015421)
0.0 0.0 GO:0008821 crossover junction endodeoxyribonuclease activity(GO:0008821)
0.0 0.1 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.0 0.4 GO:0003823 antigen binding(GO:0003823)
0.0 0.1 GO:0043425 bHLH transcription factor binding(GO:0043425)
0.0 0.0 GO:0000400 four-way junction DNA binding(GO:0000400)
0.0 0.1 GO:0001085 RNA polymerase II transcription factor binding(GO:0001085)
0.0 0.0 GO:0004449 isocitrate dehydrogenase (NAD+) activity(GO:0004449)
0.0 0.0 GO:0019863 IgE binding(GO:0019863)
0.0 0.0 GO:0019870 potassium channel inhibitor activity(GO:0019870)
0.0 0.0 GO:0004142 diacylglycerol cholinephosphotransferase activity(GO:0004142)
0.0 0.0 GO:0043398 HLH domain binding(GO:0043398)
0.0 0.1 GO:0005087 Ran guanyl-nucleotide exchange factor activity(GO:0005087)
0.0 0.0 GO:0004505 phenylalanine 4-monooxygenase activity(GO:0004505)
0.0 0.0 GO:0004966 galanin receptor activity(GO:0004966)
0.0 0.1 GO:0004957 prostaglandin E receptor activity(GO:0004957)
0.0 0.2 GO:0005527 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.0 0.1 GO:0099604 calcium-release channel activity(GO:0015278) ligand-gated calcium channel activity(GO:0099604)
0.0 0.0 GO:0015183 L-aspartate transmembrane transporter activity(GO:0015183)
0.0 0.1 GO:0008273 calcium, potassium:sodium antiporter activity(GO:0008273)
0.0 0.1 GO:0016986 obsolete transcription initiation factor activity(GO:0016986)
0.0 0.0 GO:0004965 G-protein coupled GABA receptor activity(GO:0004965)
0.0 0.0 GO:0004828 serine-tRNA ligase activity(GO:0004828)
0.0 0.2 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.0 0.0 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.0 0.1 GO:0004969 histamine receptor activity(GO:0004969)
0.0 0.0 GO:0032036 myosin heavy chain binding(GO:0032036)
0.0 0.0 GO:0015252 hydrogen ion channel activity(GO:0015252)
0.0 0.2 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.0 0.1 GO:0004791 thioredoxin-disulfide reductase activity(GO:0004791)
0.0 0.0 GO:0017159 pantetheine hydrolase activity(GO:0017159)
0.0 0.0 GO:0016361 activin receptor activity, type I(GO:0016361)
0.0 0.0 GO:0004800 thyroxine 5'-deiodinase activity(GO:0004800)
0.0 0.1 GO:0015165 pyrimidine nucleotide-sugar transmembrane transporter activity(GO:0015165)
0.0 0.1 GO:0009008 DNA-methyltransferase activity(GO:0009008)
0.0 0.1 GO:0004703 G-protein coupled receptor kinase activity(GO:0004703)
0.0 0.0 GO:0051733 ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity(GO:0046404) polydeoxyribonucleotide kinase activity(GO:0051733) ATP-dependent polynucleotide kinase activity(GO:0051734)
0.0 0.1 GO:0005031 tumor necrosis factor-activated receptor activity(GO:0005031)
0.0 0.0 GO:0016309 1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
0.0 0.1 GO:0008499 UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity(GO:0008499)
0.0 0.1 GO:0008266 poly(U) RNA binding(GO:0008266)
0.0 0.0 GO:0030197 extracellular matrix constituent, lubricant activity(GO:0030197)
0.0 0.1 GO:0001786 phosphatidylserine binding(GO:0001786)
0.0 0.0 GO:0030292 protein tyrosine kinase inhibitor activity(GO:0030292)
0.0 0.0 GO:0031957 very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.0 0.0 GO:0019788 NEDD8 transferase activity(GO:0019788)
0.0 0.0 GO:0019855 calcium channel inhibitor activity(GO:0019855)
0.0 0.0 GO:0004939 beta-adrenergic receptor activity(GO:0004939)
0.0 0.1 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.0 0.1 GO:0046934 phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) phosphatidylinositol bisphosphate kinase activity(GO:0052813)
0.0 0.5 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.0 0.1 GO:0031701 angiotensin receptor binding(GO:0031701)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.0 PID CD8 TCR PATHWAY TCR signaling in naïve CD8+ T cells
0.0 0.4 PID TCR PATHWAY TCR signaling in naïve CD4+ T cells
0.0 0.0 PID PDGFRA PATHWAY PDGFR-alpha signaling pathway
0.0 0.0 SA B CELL RECEPTOR COMPLEXES Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.0 0.1 PID S1P S1P4 PATHWAY S1P4 pathway
0.0 0.6 PID TGFBR PATHWAY TGF-beta receptor signaling
0.0 0.4 ST JNK MAPK PATHWAY JNK MAPK Pathway
0.0 0.2 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0 0.1 PID TCR RAS PATHWAY Ras signaling in the CD4+ TCR pathway
0.0 0.3 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.0 0.3 SIG PIP3 SIGNALING IN B LYMPHOCYTES Genes related to PIP3 signaling in B lymphocytes

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.0 REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE Genes involved in Translocation of ZAP-70 to Immunological synapse
0.0 0.2 REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.0 0.3 REACTOME ENOS ACTIVATION AND REGULATION Genes involved in eNOS activation and regulation
0.0 0.3 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.0 0.0 REACTOME TRAF6 MEDIATED NFKB ACTIVATION Genes involved in TRAF6 mediated NF-kB activation
0.0 0.5 REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.0 0.2 REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.0 0.0 REACTOME SIGNALING BY NOTCH4 Genes involved in Signaling by NOTCH4
0.0 0.2 REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.0 0.1 REACTOME PROSTANOID LIGAND RECEPTORS Genes involved in Prostanoid ligand receptors
0.0 0.1 REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES Genes involved in Recruitment of NuMA to mitotic centrosomes
0.0 0.3 REACTOME GPVI MEDIATED ACTIVATION CASCADE Genes involved in GPVI-mediated activation cascade
0.0 0.0 REACTOME REGULATION OF MITOTIC CELL CYCLE Genes involved in Regulation of mitotic cell cycle
0.0 0.2 REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT Genes involved in Organic cation/anion/zwitterion transport
0.0 0.2 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.0 0.1 REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the late endosome membrane
0.0 0.0 REACTOME IMMUNE SYSTEM Genes involved in Immune System
0.0 0.2 REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.0 0.0 REACTOME DSCAM INTERACTIONS Genes involved in DSCAM interactions
0.0 0.1 REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR Genes involved in Trafficking and processing of endosomal TLR
0.0 0.0 REACTOME BINDING AND ENTRY OF HIV VIRION Genes involved in Binding and entry of HIV virion
0.0 0.5 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0 0.1 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
0.0 0.0 REACTOME ENDOSOMAL VACUOLAR PATHWAY Genes involved in Endosomal/Vacuolar pathway