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ENCODE: H3K4me1 ChIP-Seq of primary human cells

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CREMA is a free online tool that recognizes most important transcription factors that change the chromatin state across different samples.

Results for SHOX

Z-value: 0.82

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Transcription factors associated with SHOX

Gene Symbol	Gene ID	Gene Info
SHOX Ensembl NCBI GeneCards UniProt	ENSG00000185960.8	SHOX
SHOX Ensembl NCBI GeneCards UniProt	ENSGR0000185960.8	SHOX

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE	Gene	Distance	Association probability	Pearson corr. coef.	P-value	Plot
SHOX	chrX_950254_950405	358787	0.008658	-0.94	2.1e-04	Click!
SHOX	chrX_598998_599149	7531	0.322550	-0.60	8.7e-02	Click!
SHOX	chrX_598763_598914	7296	0.323860	-0.54	1.4e-01	Click!
SHOX	chrX_822680_822831	231213	0.020430	-0.37	3.2e-01	Click!
SHOX	chrX_766443_766594	174976	0.034074	0.32	4.1e-01	Click!

Activity of the SHOX motif across conditions

Conditions sorted by the z-value of the SHOX motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE)	Target Score	Top associated gene	Gene Info	Distance of CRE to TSS	CRE/Gene association probability
chr1_178102702_178103151	0.84	RASAL2	RAS protein activator like 2	39650	0.22
chr11_126515519_126515813	0.58	RP11-115C10.1		7081	0.29
chr1_31870163_31870721	0.54	SERINC2	serine incorporator 2	11970	0.15
chr6_17906953_17907342	0.48	KIF13A	kinesin family member 13A	80547	0.1
chr4_22515546_22516022	0.46	GPR125	G protein-coupled receptor 125	1836	0.52
chr14_101308246_101309004	0.45	ENSG00000214548	.	7020	0.04
chr17_28275117_28275440	0.45	EFCAB5	EF-hand calcium binding domain 5	6655	0.17
chr16_24742094_24743166	0.44	TNRC6A	trinucleotide repeat containing 6A	1596	0.5
chr6_22026198_22026944	0.44	ENSG00000222515	.	59202	0.17
chr13_31774982_31775836	0.44	B3GALTL	beta 1,3-galactosyltransferase-like	1336	0.55
chr7_115994446_115994930	0.44	ENSG00000216076	.	8690	0.21
chr12_89339824_89340184	0.44	ENSG00000238302	.	336058	0.01
chrX_24073482_24074722	0.43	EIF2S3	eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa	1014	0.57
chr13_110651559_110651710	0.43	ENSG00000201161	.	84191	0.1
chr1_87801300_87801913	0.42	LMO4	LIM domain only 4	4255	0.35
chr20_39919427_39919896	0.41	ENSG00000263989	.	444	0.84
chr5_39072103_39073220	0.41	RICTOR	RPTOR independent companion of MTOR, complex 2	1830	0.43
chr5_136899227_136899378	0.41	ENSG00000221612	.	30159	0.2
chr2_60758944_60759403	0.41	BCL11A	B-cell CLL/lymphoma 11A (zinc finger protein)	21367	0.21
chr17_60074998_60075962	0.41	ENSG00000242398	.	7868	0.17
chr6_139912713_139913098	0.40	CITED2	Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2	217148	0.02
chr5_139626504_139626769	0.40	CTB-131B5.2		46888	0.09
chr10_65024052_65024675	0.39	JMJD1C	jumonji domain containing 1C	4463	0.31
chr3_131121908_131122099	0.39	NUDT16	nudix (nucleoside diphosphate linked moiety X)-type motif 16	21374	0.15
chr15_101668768_101669069	0.39	RP11-505E24.2		42647	0.16
chr9_14205951_14206102	0.39	NFIB	nuclear factor I/B	25229	0.27
chr3_188995375_188995558	0.38	TPRG1-AS2	TPRG1 antisense RNA 2	37083	0.21
chr3_149160630_149160781	0.38	TM4SF4	transmembrane 4 L six family member 4	31056	0.16
chr6_51167339_51167725	0.37	ENSG00000212532	.	161956	0.04
chr6_17972496_17972680	0.36	KIF13A	kinesin family member 13A	15106	0.27
chr7_46949633_46949784	0.36	AC011294.3	Uncharacterized protein	212988	0.03
chr9_81321983_81322311	0.35	PSAT1	phosphoserine aminotransferase 1	410088	0.01
chr7_137276747_137277035	0.35	PTN	pleiotrophin	248280	0.02
chr18_32353571_32353898	0.35	RP11-138H11.1		6107	0.24
chr5_81460698_81461288	0.34	ENSG00000265684	.	86747	0.08
chr18_22012413_22012586	0.34	RP11-178F10.1		2829	0.18
chr3_98481605_98482039	0.34	ST3GAL6	ST3 beta-galactoside alpha-2,3-sialyltransferase 6	339	0.89
chr11_33934050_33934291	0.34	LMO2	LIM domain only 2 (rhombotin-like 1)	20334	0.2
chr13_24782132_24782457	0.33	SPATA13	spermatogenesis associated 13	43538	0.13
chr17_31210230_31210381	0.33	MYO1D	myosin ID	6110	0.19
chr7_115872460_115873536	0.33	AC073130.3		6307	0.23
chr1_43151129_43151715	0.33	YBX1	Y box binding protein 1	2764	0.23
chr10_74472843_74472994	0.33	MCU	mitochondrial calcium uniporter	856	0.58
chr9_4137653_4137928	0.33	GLIS3	GLIS family zinc finger 3	7403	0.28
chr7_33973779_33973930	0.33	BMPER	BMP binding endothelial regulator	28709	0.26
chr22_24798801_24798960	0.32	ADORA2A	adenosine A2a receptor	20685	0.18
chr18_456798_457125	0.32	RP11-720L2.2		32545	0.16
chr12_10344371_10344522	0.32	TMEM52B	transmembrane protein 52B	12333	0.12
chr4_140958813_140959347	0.32	RP11-392B6.1		90089	0.09
chr3_47203435_47204414	0.32	SETD2	SET domain containing 2	1142	0.44
chr5_158267521_158267691	0.32	CTD-2363C16.1		142408	0.05
chr10_68595409_68595560	0.32	LRRTM3	leucine rich repeat transmembrane neuronal 3	90280	0.1
chr3_177443249_177443545	0.32	ENSG00000200288	.	101200	0.08
chr6_2103859_2104525	0.31	GMDS	GDP-mannose 4,6-dehydratase	72033	0.13
chr16_50059665_50060650	0.31	CNEP1R1	CTD nuclear envelope phosphatase 1 regulatory subunit 1	86	0.97
chr9_90215657_90216062	0.31	DAPK1-IT1	DAPK1 intronic transcript 1 (non-protein coding)	47490	0.16
chr9_130302299_130302610	0.31	FAM129B	family with sequence similarity 129, member B	28913	0.13
chr9_75764547_75765336	0.31	ANXA1	annexin A1	1732	0.5
chr1_61401333_61401664	0.31	RP4-668G5.1		17023	0.26
chr3_156478754_156479058	0.31	LEKR1	leucine, glutamate and lysine rich 1	65183	0.12
chr1_68823989_68824140	0.31	RPE65	retinal pigment epithelium-specific protein 65kDa	91578	0.08
chr8_110304919_110305151	0.31	RP11-122A21.2		5792	0.23
chr6_17933009_17933323	0.31	KIF13A	kinesin family member 13A	54528	0.15
chr1_200333826_200333977	0.30	ZNF281	zinc finger protein 281	45219	0.19
chr3_197098695_197098846	0.30	ENSG00000238491	.	32348	0.17
chr6_144587139_144587431	0.30	UTRN	utrophin	19552	0.24
chr5_40608102_40608403	0.30	ENSG00000199552	.	46813	0.16
chr15_78594610_78594888	0.30	WDR61	WD repeat domain 61	2613	0.18
chr4_75072940_75073180	0.30	AC093677.1	Uncharacterized protein	48975	0.12
chr8_143757168_143757384	0.29	PSCA	prostate stem cell antigen	4598	0.13
chr22_38795449_38796163	0.29	CSNK1E	casein kinase 1, epsilon	1279	0.34
chr17_65372251_65373170	0.29	PITPNC1	phosphatidylinositol transfer protein, cytoplasmic 1	865	0.53
chr6_114196551_114196945	0.29	MARCKS	myristoylated alanine-rich protein kinase C substrate	18207	0.17
chr12_65369994_65370192	0.29	ENSG00000221564	.	37290	0.18
chr7_92393722_92393991	0.29	ENSG00000206763	.	62728	0.11
chr4_48951442_48951593	0.29	ENSG00000252913	.	16646	0.19
chr4_85891142_85891293	0.29	WDFY3	WD repeat and FYVE domain containing 3	3673	0.34
chr1_109934550_109935130	0.29	SORT1	sortilin 1	1139	0.45
chr14_61720277_61720459	0.29	ENSG00000252380	.	9382	0.2
chr4_86849951_86850102	0.29	ARHGAP24	Rho GTPase activating protein 24	1400	0.47
chr13_77713051_77713202	0.28	MYCBP2	MYC binding protein 2, E3 ubiquitin protein ligase	51477	0.13
chr5_110849348_110849548	0.28	STARD4	StAR-related lipid transfer (START) domain containing 4	1160	0.42
chr1_202545395_202545546	0.28	RP11-569A11.1		27926	0.17
chr10_22014116_22014329	0.28	MLLT10	myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10	51715	0.13
chr14_103480838_103481545	0.28	CDC42BPB	CDC42 binding protein kinase beta (DMPK-like)	42608	0.12
chr2_172251255_172251518	0.28	METTL8	methyltransferase like 8	39114	0.17
chr2_67877898_67878049	0.28	ETAA1	Ewing tumor-associated antigen 1	253522	0.02
chr2_148804260_148804811	0.28	ORC4	origin recognition complex, subunit 4	25388	0.19
chr1_83043773_83044235	0.28	LPHN2	latrophilin 2	598431	0.0
chrX_45617210_45617605	0.28	ENSG00000207725	.	10877	0.24
chr1_33853388_33853681	0.28	PHC2	polyhomeotic homolog 2 (Drosophila)	12340	0.15
chr20_44601777_44602076	0.28	ZNF335	zinc finger protein 335	1093	0.38
chr7_80350905_80351077	0.28	CD36	CD36 molecule (thrombospondin receptor)	48299	0.19
chr3_101659041_101659481	0.28	ENSG00000202177	.	14660	0.24
chr9_83650488_83650760	0.28	ENSG00000221581	.	301380	0.01
chr5_129440440_129440591	0.28	ENSG00000199455	.	9587	0.3
chr17_29906221_29906372	0.28	ENSG00000199187	.	3866	0.14
chr1_210550900_210551051	0.28	ENSG00000200972	.	3364	0.3
chr6_25005285_25005494	0.28	ENSG00000244618	.	26121	0.17
chr6_160150691_160151658	0.28	WTAP	Wilms tumor 1 associated protein	2554	0.18
chr14_50317979_50318647	0.28	NEMF	nuclear export mediator factor	1185	0.29
chr22_26717807_26718076	0.28	SEZ6L	seizure related 6 homolog (mouse)-like	25740	0.18
chr8_108235226_108235555	0.28	ENSG00000211995	.	31336	0.25
chr15_101143578_101144308	0.28	ASB7	ankyrin repeat and SOCS box containing 7	1129	0.36
chr4_24553435_24554115	0.27	ENSG00000243005	.	11309	0.21
chr12_52348007_52348213	0.27	ACVR1B	activin A receptor, type IB	946	0.5
chr21_39723989_39724317	0.27	KCNJ15	potassium inwardly-rectifying channel, subfamily J, member 15	55305	0.16
chr4_141446173_141446497	0.27	ELMOD2	ELMO/CED-12 domain containing 2	745	0.66
chr4_40623166_40623743	0.27	RBM47	RNA binding motif protein 47	8427	0.27
chr4_170165351_170165677	0.27	SH3RF1	SH3 domain containing ring finger 1	25594	0.22
chr6_56591218_56591369	0.27	DST	dystonin	59384	0.15
chr9_94178983_94179134	0.27	NFIL3	nuclear factor, interleukin 3 regulated	7086	0.3
chr6_15349427_15349643	0.27	ENSG00000201519	.	24832	0.19
chr4_86683324_86683672	0.27	ARHGAP24	Rho GTPase activating protein 24	16361	0.24
chr3_111431650_111431801	0.27	PHLDB2	pleckstrin homology-like domain, family B, member 2	19619	0.18
chr3_114082824_114082975	0.27	ZBTB20-AS1	ZBTB20 antisense RNA 1	2665	0.28
chr18_72443447_72443598	0.27	ZNF407	zinc finger protein 407	100546	0.08
chr19_11454879_11455424	0.27	CCDC159	coiled-coil domain containing 159	826	0.33
chr11_69084536_69085027	0.27	MYEOV	myeloma overexpressed	23156	0.25
chr1_50589510_50589806	0.27	ELAVL4	ELAV like neuron-specific RNA binding protein 4	14280	0.23
chr4_169526190_169526341	0.27	PALLD	palladin, cytoskeletal associated protein	26501	0.19
chr6_138820271_138821054	0.27	NHSL1	NHS-like 1	31	0.98
chr1_201425767_201426025	0.27	PHLDA3	pleckstrin homology-like domain, family A, member 3	12416	0.15
chr2_153441109_153441260	0.27	FMNL2	formin-like 2	34908	0.22
chr3_37114880_37115172	0.26	LRRFIP2	leucine rich repeat (in FLII) interacting protein 2	10215	0.17
chr1_214721687_214721838	0.26	PTPN14	protein tyrosine phosphatase, non-receptor type 14	2804	0.37
chr18_10213675_10214158	0.26	ENSG00000239031	.	176081	0.03
chr16_70734339_70734664	0.26	VAC14	Vac14 homolog (S. cerevisiae)	353	0.84
chr1_85873119_85873270	0.26	DDAH1	dimethylarginine dimethylaminohydrolase 1	3014	0.28
chr5_66255925_66256427	0.26	MAST4	microtubule associated serine/threonine kinase family member 4	1360	0.56
chr11_96059054_96059205	0.26	ENSG00000266192	.	15473	0.19
chr6_82477389_82477689	0.26	ENSG00000206886	.	3798	0.25
chr15_34392588_34393242	0.26	EMC7	ER membrane protein complex subunit 7	1093	0.39
chr3_81777841_81778131	0.26	GBE1	glucan (1,4-alpha-), branching enzyme 1	14794	0.31
chr5_53387008_53387159	0.26	ENSG00000265421	.	15670	0.24
chr1_109938801_109939938	0.26	SORT1	sortilin 1	1204	0.42
chr18_70676877_70677028	0.26	NETO1	neuropilin (NRP) and tolloid (TLL)-like 1	141768	0.05
chr1_76191648_76191845	0.26	ACADM	acyl-CoA dehydrogenase, C-4 to C-12 straight chain	1281	0.36
chr8_38264429_38264741	0.26	RP11-350N15.6		1675	0.23
chr1_227379724_227379875	0.26	RP11-1B20.1		13765	0.27
chr9_19119177_19119410	0.26	PLIN2	perilipin 2	8181	0.13
chr2_97187296_97187447	0.26	RP11-363D14.1		10672	0.17
chr12_98834191_98834342	0.26	ENSG00000201296	.	22450	0.18
chr9_125766060_125766211	0.26	RABGAP1	RAB GTPase activating protein 1	29653	0.12
chr4_95470032_95470452	0.26	PDLIM5	PDZ and LIM domain 5	25366	0.27
chr3_128914264_128914631	0.26	CNBP	CCHC-type zinc finger, nucleic acid binding protein	11682	0.14
chr3_123476973_123477366	0.26	MYLK	myosin light chain kinase	35519	0.15
chr11_111794482_111794633	0.26	CRYAB	crystallin, alpha B	111	0.93
chr1_28797868_28798297	0.26	ENSG00000221216	.	9792	0.12
chr3_159600901_159601361	0.26	SCHIP1	schwannomin interacting protein 1	30403	0.17
chr21_34696241_34696651	0.26	IFNAR1	interferon (alpha, beta and omega) receptor 1	288	0.9
chr8_142158040_142158331	0.26	DENND3	DENN/MADD domain containing 3	6883	0.21
chr18_8662206_8662357	0.25	RP11-661O13.1		25936	0.15
chr1_173159483_173159962	0.25	TNFSF4	tumor necrosis factor (ligand) superfamily, member 4	14975	0.26
chr3_58044055_58044466	0.25	FLNB	filamin B, beta	19796	0.24
chr4_77067380_77067910	0.25	NUP54	nucleoporin 54kDa	1905	0.31
chr7_1462493_1462644	0.25	MICALL2	MICAL-like 2	36394	0.13
chr16_72928505_72928656	0.25	ENSG00000251868	.	72689	0.09
chr7_17412244_17412395	0.25	ENSG00000199473	.	631	0.81
chr6_17962920_17963120	0.25	KIF13A	kinesin family member 13A	24674	0.24
chr5_14154020_14154339	0.25	TRIO	trio Rho guanine nucleotide exchange factor	10350	0.32
chr7_127410389_127410540	0.25	SND1	staphylococcal nuclease and tudor domain containing 1	117501	0.05
chr15_36043717_36043868	0.25	ENSG00000265098	.	175265	0.03
chr1_178027486_178027784	0.25	RASAL2	RAS protein activator like 2	35229	0.22
chr14_74724538_74725207	0.25	VSX2	visual system homeobox 2	18697	0.14
chr9_117877775_117877926	0.25	TNC	tenascin C	2628	0.36
chr15_59641636_59642058	0.25	ENSG00000199512	.	8231	0.13
chr13_98867933_98868084	0.25	ENSG00000263399	.	7230	0.16
chr2_174862628_174862955	0.25	SP3	Sp3 transcription factor	32361	0.24
chr1_200865216_200865405	0.25	C1orf106	chromosome 1 open reading frame 106	1361	0.42
chr20_52352229_52352983	0.25	ENSG00000238468	.	67309	0.12
chr9_111235960_111236111	0.25	ENSG00000222512	.	114826	0.07
chr20_46413000_46413151	0.25	SULF2	sulfatase 2	1158	0.56
chr5_149679633_149679784	0.25	ARSI	arylsulfatase family, member I	2808	0.25
chr3_152019223_152020002	0.25	MBNL1	muscleblind-like splicing regulator 1	1625	0.43
chr8_91783068_91783219	0.25	NECAB1	N-terminal EF-hand calcium binding protein 1	20635	0.19
chr1_44966238_44966535	0.25	ENSG00000263381	.	44779	0.13
chr6_91247685_91248060	0.25	MAP3K7	mitogen-activated protein kinase kinase kinase 7	15311	0.28
chr10_95236478_95236629	0.25	MYOF	myoferlin	5398	0.21
chr3_101944186_101944337	0.25	ZPLD1	zona pellucida-like domain containing 1	126173	0.06
chr16_69510453_69510859	0.25	CYB5B	cytochrome b5 type B (outer mitochondrial membrane)	51970	0.1
chr3_174159594_174160082	0.25	NAALADL2	N-acetylated alpha-linked acidic dipeptidase-like 2	1061	0.7
chr12_85859290_85859441	0.25	ENSG00000263449	.	181733	0.03
chr4_16034494_16034749	0.25	ENSG00000251758	.	24211	0.19
chr18_52933640_52933791	0.25	TCF4	transcription factor 4	9187	0.3
chr5_148365723_148365874	0.25	RP11-44B19.1		15895	0.18
chr5_139968834_139969062	0.25	ENSG00000200235	.	9696	0.08
chr15_96102794_96102945	0.25	ENSG00000222076	.	186164	0.03
chr11_60686848_60686999	0.24	TMEM109	transmembrane protein 109	227	0.84
chr6_147224333_147224539	0.24	STXBP5-AS1	STXBP5 antisense RNA 1	8306	0.31
chr22_40574959_40575808	0.24	TNRC6B	trinucleotide repeat containing 6B	1437	0.53
chr6_71958596_71958951	0.24	RP11-154D6.1		35862	0.16
chr8_38266802_38267077	0.24	RP11-350N15.6		679	0.57
chr3_177463007_177463158	0.24	ENSG00000200288	.	120885	0.06
chr20_45987046_45987328	0.24	ZMYND8	zinc finger, MYND-type containing 8	1620	0.29
chr10_101431369_101431801	0.24	ENTPD7	ectonucleoside triphosphate diphosphohydrolase 7	12322	0.15
chr12_32268914_32269294	0.24	RP11-843B15.2		8642	0.23
chr7_1443816_1444071	0.24	MICALL2	MICAL-like 2	55019	0.11
chr20_8413517_8413855	0.24	ENSG00000221201	.	176141	0.03
chr4_85836939_85837233	0.24	ENSG00000252062	.	29447	0.21

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of SHOX

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View png image

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.4	GO:0032509	endosome transport via multivesicular body sorting pathway(GO:0032509)
0.1	0.5	GO:0072383	plus-end-directed vesicle transport along microtubule(GO:0072383) plus-end-directed organelle transport along microtubule(GO:0072386)
0.1	0.2	GO:2000095	regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000095)
0.1	0.7	GO:0007185	transmembrane receptor protein tyrosine phosphatase signaling pathway(GO:0007185)
0.1	0.3	GO:0021825	cerebral cortex tangential migration using cell-cell interactions(GO:0021823) substrate-dependent cerebral cortex tangential migration(GO:0021825) postnatal olfactory bulb interneuron migration(GO:0021827)
0.1	0.3	GO:0031340	positive regulation of vesicle fusion(GO:0031340)
0.1	0.3	GO:0070141	response to UV-A(GO:0070141)
0.1	0.3	GO:0071692	sequestering of extracellular ligand from receptor(GO:0035581) sequestering of TGFbeta in extracellular matrix(GO:0035583) protein localization to extracellular region(GO:0071692) maintenance of protein location in extracellular region(GO:0071694) extracellular regulation of signal transduction(GO:1900115) extracellular negative regulation of signal transduction(GO:1900116)
0.1	0.3	GO:0072010	renal filtration cell differentiation(GO:0061318) glomerular epithelium development(GO:0072010) glomerular visceral epithelial cell differentiation(GO:0072112) glomerular epithelial cell differentiation(GO:0072311)
0.1	0.5	GO:0007171	activation of transmembrane receptor protein tyrosine kinase activity(GO:0007171)
0.1	0.5	GO:0007442	hindgut morphogenesis(GO:0007442) hindgut development(GO:0061525)
0.1	0.2	GO:0071436	sodium ion export(GO:0071436)
0.1	0.2	GO:0032467	positive regulation of cytokinesis(GO:0032467)
0.1	0.2	GO:0045578	negative regulation of B cell differentiation(GO:0045578)
0.1	0.2	GO:0030948	negative regulation of vascular endothelial growth factor receptor signaling pathway(GO:0030948)
0.1	0.3	GO:0019934	cGMP-mediated signaling(GO:0019934)
0.1	0.3	GO:0071731	response to nitric oxide(GO:0071731)
0.1	0.2	GO:0001543	ovarian follicle rupture(GO:0001543)
0.1	0.2	GO:0007221	positive regulation of transcription of Notch receptor target(GO:0007221)
0.1	0.3	GO:0007386	compartment pattern specification(GO:0007386)
0.1	0.1	GO:0002043	blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:0002043)
0.1	0.1	GO:0010193	response to ozone(GO:0010193)
0.1	0.1	GO:0019372	lipoxygenase pathway(GO:0019372)
0.1	0.4	GO:0061001	dendritic spine morphogenesis(GO:0060997) regulation of dendritic spine morphogenesis(GO:0061001) dendritic spine organization(GO:0097061)
0.1	0.2	GO:0018242	protein O-linked glycosylation via serine(GO:0018242) protein O-linked glycosylation via threonine(GO:0018243)
0.1	0.1	GO:2000192	negative regulation of plasma membrane long-chain fatty acid transport(GO:0010748) negative regulation of anion transmembrane transport(GO:1903960) negative regulation of fatty acid transport(GO:2000192)
0.1	0.3	GO:0009249	protein lipoylation(GO:0009249)
0.1	0.1	GO:0071379	cellular response to prostaglandin stimulus(GO:0071379)
0.1	0.2	GO:0043589	skin morphogenesis(GO:0043589)
0.1	0.3	GO:0060638	mesenchymal-epithelial cell signaling(GO:0060638)
0.1	0.2	GO:0015889	cobalamin transport(GO:0015889)
0.1	0.3	GO:0035414	negative regulation of catenin import into nucleus(GO:0035414)
0.1	0.2	GO:0055098	response to low-density lipoprotein particle(GO:0055098)
0.1	0.2	GO:0032632	interleukin-3 production(GO:0032632)
0.1	0.1	GO:0006883	cellular sodium ion homeostasis(GO:0006883)
0.1	0.3	GO:0016322	neuron remodeling(GO:0016322)
0.1	0.2	GO:0060083	smooth muscle contraction involved in micturition(GO:0060083)
0.1	0.2	GO:0048808	male genitalia morphogenesis(GO:0048808) male anatomical structure morphogenesis(GO:0090598)
0.1	0.2	GO:0017121	phospholipid scrambling(GO:0017121)
0.0	0.0	GO:0048631	regulation of skeletal muscle tissue growth(GO:0048631)
0.0	0.1	GO:0022605	oogenesis stage(GO:0022605)
0.0	0.2	GO:0006654	phosphatidic acid biosynthetic process(GO:0006654)
0.0	0.2	GO:0060028	convergent extension involved in axis elongation(GO:0060028)
0.0	0.1	GO:0003308	negative regulation of Wnt signaling pathway involved in heart development(GO:0003308)
0.0	0.1	GO:0060129	thyroid-stimulating hormone-secreting cell differentiation(GO:0060129)
0.0	0.1	GO:0001778	plasma membrane repair(GO:0001778)
0.0	0.1	GO:0072201	negative regulation of mesenchymal cell proliferation(GO:0072201)
0.0	0.3	GO:0015871	choline transport(GO:0015871)
0.0	0.1	GO:0032927	positive regulation of activin receptor signaling pathway(GO:0032927)
0.0	0.2	GO:0051497	negative regulation of stress fiber assembly(GO:0051497)
0.0	0.1	GO:0010815	bradykinin catabolic process(GO:0010815)
0.0	0.1	GO:0035234	ectopic germ cell programmed cell death(GO:0035234)
0.0	0.0	GO:0003032	detection of oxygen(GO:0003032)
0.0	0.1	GO:0051124	synaptic growth at neuromuscular junction(GO:0051124)
0.0	0.1	GO:0031659	regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition of mitotic cell cycle(GO:0031657) positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition of mitotic cell cycle(GO:0031659)
0.0	0.4	GO:0019369	arachidonic acid metabolic process(GO:0019369)
0.0	0.1	GO:0051280	negative regulation of release of sequestered calcium ion into cytosol(GO:0051280) positive regulation of sequestering of calcium ion(GO:0051284) negative regulation of calcium ion transmembrane transport(GO:1903170)
0.0	0.2	GO:0045091	regulation of single stranded viral RNA replication via double stranded DNA intermediate(GO:0045091)
0.0	0.3	GO:0040037	negative regulation of fibroblast growth factor receptor signaling pathway(GO:0040037)
0.0	0.1	GO:0070672	response to interleukin-15(GO:0070672)
0.0	0.2	GO:0048853	forebrain morphogenesis(GO:0048853)
0.0	0.1	GO:0006166	purine ribonucleoside salvage(GO:0006166)
0.0	0.2	GO:0002283	neutrophil activation involved in immune response(GO:0002283) neutrophil degranulation(GO:0043312)
0.0	0.1	GO:0000089	mitotic metaphase(GO:0000089)
0.0	0.1	GO:0043490	malate-aspartate shuttle(GO:0043490)
0.0	0.1	GO:0010757	negative regulation of plasminogen activation(GO:0010757)
0.0	0.1	GO:0001996	positive regulation of heart rate by epinephrine-norepinephrine(GO:0001996)
0.0	0.1	GO:0048149	behavioral response to ethanol(GO:0048149)
0.0	0.0	GO:0007621	negative regulation of female receptivity(GO:0007621)
0.0	0.2	GO:0045793	positive regulation of cell size(GO:0045793)
0.0	0.1	GO:0048143	astrocyte activation(GO:0048143)
0.0	0.1	GO:0060839	endothelial cell fate commitment(GO:0060839)
0.0	0.1	GO:0010837	regulation of keratinocyte proliferation(GO:0010837)
0.0	0.1	GO:0009756	carbohydrate mediated signaling(GO:0009756)
0.0	0.1	GO:0010842	retina layer formation(GO:0010842)
0.0	0.1	GO:0009169	purine nucleoside monophosphate catabolic process(GO:0009128) ribonucleoside monophosphate catabolic process(GO:0009158) purine ribonucleoside monophosphate catabolic process(GO:0009169)
0.0	0.1	GO:0045162	clustering of voltage-gated sodium channels(GO:0045162)
0.0	0.1	GO:0034063	stress granule assembly(GO:0034063)
0.0	0.1	GO:0033262	regulation of nuclear cell cycle DNA replication(GO:0033262)
0.0	0.2	GO:0045652	regulation of megakaryocyte differentiation(GO:0045652) regulation of hematopoietic progenitor cell differentiation(GO:1901532)
0.0	0.3	GO:0007184	SMAD protein import into nucleus(GO:0007184)
0.0	0.4	GO:0034605	cellular response to heat(GO:0034605)
0.0	0.1	GO:0002495	antigen processing and presentation of peptide antigen via MHC class II(GO:0002495)
0.0	0.2	GO:0010452	histone H3-K36 methylation(GO:0010452)
0.0	0.1	GO:0060762	regulation of branching involved in mammary gland duct morphogenesis(GO:0060762)
0.0	0.1	GO:0048539	bone marrow development(GO:0048539)
0.0	0.1	GO:2000980	regulation of auditory receptor cell differentiation(GO:0045607) regulation of mechanoreceptor differentiation(GO:0045631) regulation of inner ear receptor cell differentiation(GO:2000980)
0.0	0.1	GO:0060841	venous blood vessel development(GO:0060841)
0.0	0.1	GO:0071421	manganese ion transmembrane transport(GO:0071421)
0.0	0.1	GO:0060754	mast cell chemotaxis(GO:0002551) regulation of mast cell chemotaxis(GO:0060753) positive regulation of mast cell chemotaxis(GO:0060754) mast cell migration(GO:0097531)
0.0	0.1	GO:0048003	antigen processing and presentation of lipid antigen via MHC class Ib(GO:0048003)
0.0	0.0	GO:0048791	calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.0	0.1	GO:0051570	regulation of histone H3-K9 methylation(GO:0051570)
0.0	0.0	GO:0070254	mucus secretion(GO:0070254)
0.0	0.1	GO:0007412	axon target recognition(GO:0007412)
0.0	0.1	GO:0033860	regulation of NAD(P)H oxidase activity(GO:0033860)
0.0	0.1	GO:0006564	L-serine biosynthetic process(GO:0006564)
0.0	0.4	GO:0035329	hippo signaling(GO:0035329)
0.0	0.1	GO:0046940	nucleoside monophosphate phosphorylation(GO:0046940)
0.0	0.1	GO:0061302	smooth muscle cell-matrix adhesion(GO:0061302)
0.0	0.1	GO:0006065	UDP-glucuronate biosynthetic process(GO:0006065)
0.0	0.1	GO:0021799	cerebral cortex radially oriented cell migration(GO:0021799)
0.0	0.1	GO:0034135	regulation of toll-like receptor 2 signaling pathway(GO:0034135)
0.0	0.2	GO:0009629	response to gravity(GO:0009629)
0.0	0.1	GO:0009649	entrainment of circadian clock(GO:0009649)
0.0	0.1	GO:0060040	retinal bipolar neuron differentiation(GO:0060040)
0.0	0.1	GO:0042637	catagen(GO:0042637)
0.0	0.1	GO:0002220	innate immune response activating cell surface receptor signaling pathway(GO:0002220)
0.0	0.1	GO:0002072	optic cup morphogenesis involved in camera-type eye development(GO:0002072)
0.0	0.1	GO:0090050	positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050) positive regulation of sprouting angiogenesis(GO:1903672)
0.0	0.1	GO:0005981	regulation of glycogen catabolic process(GO:0005981)
0.0	0.1	GO:0003356	regulation of cilium movement(GO:0003352) regulation of cilium beat frequency(GO:0003356) cilium movement involved in cell motility(GO:0060294) regulation of cilium movement involved in cell motility(GO:0060295) regulation of cilium beat frequency involved in ciliary motility(GO:0060296) regulation of cilium-dependent cell motility(GO:1902019)
0.0	0.1	GO:0045647	negative regulation of erythrocyte differentiation(GO:0045647)
0.0	0.1	GO:0009786	regulation of asymmetric cell division(GO:0009786)
0.0	0.1	GO:0010765	positive regulation of sodium ion transport(GO:0010765)
0.0	0.2	GO:0010269	response to selenium ion(GO:0010269)
0.0	0.0	GO:0031050	dsRNA fragmentation(GO:0031050) production of small RNA involved in gene silencing by RNA(GO:0070918)
0.0	0.0	GO:0010966	regulation of phosphate transport(GO:0010966)
0.0	0.1	GO:0008300	isoprenoid catabolic process(GO:0008300)
0.0	0.3	GO:0045600	positive regulation of fat cell differentiation(GO:0045600)
0.0	0.1	GO:0045747	positive regulation of Notch signaling pathway(GO:0045747)
0.0	0.1	GO:0030091	protein repair(GO:0030091)
0.0	0.1	GO:0051014	actin filament severing(GO:0051014)
0.0	0.1	GO:0008356	asymmetric cell division(GO:0008356)
0.0	0.1	GO:0060039	pericardium development(GO:0060039)
0.0	0.1	GO:0007144	female meiosis I(GO:0007144)
0.0	0.0	GO:0043552	positive regulation of phosphatidylinositol 3-kinase activity(GO:0043552)
0.0	0.1	GO:0060164	regulation of timing of neuron differentiation(GO:0060164)
0.0	0.2	GO:0048844	artery morphogenesis(GO:0048844) artery development(GO:0060840)
0.0	0.1	GO:0006776	vitamin A metabolic process(GO:0006776)
0.0	0.0	GO:0048541	Peyer's patch development(GO:0048541)
0.0	0.0	GO:0043653	mitochondrial fragmentation involved in apoptotic process(GO:0043653)
0.0	0.1	GO:0046835	carbohydrate phosphorylation(GO:0046835)
0.0	0.1	GO:0008295	spermidine biosynthetic process(GO:0008295)
0.0	0.0	GO:0061298	retina vasculature development in camera-type eye(GO:0061298) retina vasculature morphogenesis in camera-type eye(GO:0061299)
0.0	0.1	GO:0014912	negative regulation of smooth muscle cell migration(GO:0014912)
0.0	0.1	GO:0030579	ubiquitin-dependent SMAD protein catabolic process(GO:0030579)
0.0	0.6	GO:0010811	positive regulation of cell-substrate adhesion(GO:0010811)
0.0	0.1	GO:0009200	deoxyribonucleoside triphosphate metabolic process(GO:0009200)
0.0	0.1	GO:0032898	neurotrophin production(GO:0032898)
0.0	0.1	GO:0061081	positive regulation of myeloid leukocyte cytokine production involved in immune response(GO:0061081)
0.0	0.0	GO:0036072	intramembranous ossification(GO:0001957) direct ossification(GO:0036072)
0.0	0.0	GO:0022038	corpus callosum development(GO:0022038)
0.0	0.0	GO:0002328	pro-B cell differentiation(GO:0002328)
0.0	0.1	GO:0043457	regulation of cellular respiration(GO:0043457)
0.0	0.2	GO:0060216	definitive hemopoiesis(GO:0060216)
0.0	0.1	GO:0051323	metaphase(GO:0051323)
0.0	0.1	GO:0046121	deoxyribonucleoside catabolic process(GO:0046121)
0.0	0.4	GO:0030032	lamellipodium assembly(GO:0030032)
0.0	0.0	GO:0031558	obsolete induction of apoptosis in response to chemical stimulus(GO:0031558)
0.0	0.6	GO:0048813	dendrite morphogenesis(GO:0048813)
0.0	0.1	GO:0032020	ISG15-protein conjugation(GO:0032020)
0.0	0.0	GO:0002407	dendritic cell chemotaxis(GO:0002407) dendritic cell migration(GO:0036336)
0.0	0.1	GO:0034204	lipid translocation(GO:0034204) phospholipid translocation(GO:0045332)
0.0	0.1	GO:0042640	anagen(GO:0042640)
0.0	0.2	GO:0006527	arginine catabolic process(GO:0006527)
0.0	0.0	GO:0033197	response to vitamin E(GO:0033197)
0.0	0.1	GO:0097094	cranial suture morphogenesis(GO:0060363) craniofacial suture morphogenesis(GO:0097094)
0.0	0.1	GO:0051967	negative regulation of synaptic transmission, glutamatergic(GO:0051967)
0.0	0.1	GO:0000712	resolution of meiotic recombination intermediates(GO:0000712) meiotic chromosome separation(GO:0051307)
0.0	0.1	GO:0010886	positive regulation of cholesterol storage(GO:0010886)
0.0	0.1	GO:0048702	embryonic neurocranium morphogenesis(GO:0048702)
0.0	0.3	GO:0030199	collagen fibril organization(GO:0030199)
0.0	0.1	GO:0007598	blood coagulation, extrinsic pathway(GO:0007598)
0.0	0.1	GO:0009886	post-embryonic morphogenesis(GO:0009886)
0.0	0.0	GO:0060437	lung growth(GO:0060437)
0.0	0.7	GO:0060606	tube closure(GO:0060606)
0.0	0.1	GO:0030490	maturation of SSU-rRNA(GO:0030490)
0.0	0.1	GO:0033539	fatty acid beta-oxidation using acyl-CoA dehydrogenase(GO:0033539)
0.0	0.2	GO:0007603	phototransduction, visible light(GO:0007603)
0.0	0.1	GO:0001866	NK T cell proliferation(GO:0001866)
0.0	0.1	GO:0001547	antral ovarian follicle growth(GO:0001547)
0.0	0.1	GO:0048245	eosinophil chemotaxis(GO:0048245) eosinophil migration(GO:0072677)
0.0	0.1	GO:0021952	central nervous system projection neuron axonogenesis(GO:0021952)
0.0	0.1	GO:0032780	negative regulation of ATPase activity(GO:0032780)
0.0	0.1	GO:0016999	antibiotic metabolic process(GO:0016999) antibiotic biosynthetic process(GO:0017000)
0.0	0.1	GO:0061037	negative regulation of chondrocyte differentiation(GO:0032331) negative regulation of cartilage development(GO:0061037)
0.0	0.4	GO:0009250	glycogen biosynthetic process(GO:0005978) glucan biosynthetic process(GO:0009250)
0.0	0.1	GO:0018345	protein palmitoylation(GO:0018345)
0.0	0.1	GO:0070634	transepithelial ammonium transport(GO:0070634)
0.0	0.1	GO:0001841	neural tube formation(GO:0001841)
0.0	0.3	GO:0035195	gene silencing by miRNA(GO:0035195)
0.0	0.1	GO:0015722	canalicular bile acid transport(GO:0015722)
0.0	0.1	GO:0055093	response to increased oxygen levels(GO:0036296) response to hyperoxia(GO:0055093)
0.0	0.0	GO:0051132	NK T cell activation(GO:0051132) regulation of NK T cell activation(GO:0051133) positive regulation of NK T cell activation(GO:0051135)
0.0	0.1	GO:0046520	sphingoid biosynthetic process(GO:0046520)
0.0	0.0	GO:0072189	ureter development(GO:0072189)
0.0	0.0	GO:0043438	acetoacetic acid metabolic process(GO:0043438)
0.0	0.0	GO:0046826	negative regulation of protein export from nucleus(GO:0046826)
0.0	0.1	GO:0014049	positive regulation of glutamate secretion(GO:0014049)
0.0	0.3	GO:0006004	fucose metabolic process(GO:0006004)
0.0	0.3	GO:0016998	cell wall macromolecule catabolic process(GO:0016998)
0.0	0.1	GO:0008053	mitochondrial fusion(GO:0008053)
0.0	0.1	GO:0034505	tooth mineralization(GO:0034505)
0.0	0.1	GO:0006108	malate metabolic process(GO:0006108)
0.0	0.0	GO:0021563	glossopharyngeal nerve development(GO:0021563) glossopharyngeal nerve morphogenesis(GO:0021615)
0.0	0.0	GO:0032525	somite rostral/caudal axis specification(GO:0032525)
0.0	0.1	GO:0043569	negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569)
0.0	0.1	GO:0046498	S-adenosylhomocysteine metabolic process(GO:0046498)
0.0	0.1	GO:0060395	SMAD protein signal transduction(GO:0060395)
0.0	0.1	GO:0048170	positive regulation of long-term neuronal synaptic plasticity(GO:0048170)
0.0	0.0	GO:0070244	negative regulation of thymocyte apoptotic process(GO:0070244)
0.0	0.1	GO:0060612	adipose tissue development(GO:0060612)
0.0	0.1	GO:0060236	regulation of mitotic spindle organization(GO:0060236)
0.0	0.1	GO:2000757	negative regulation of histone acetylation(GO:0035067) negative regulation of protein acetylation(GO:1901984) negative regulation of peptidyl-lysine acetylation(GO:2000757)
0.0	0.0	GO:0060119	inner ear receptor cell development(GO:0060119)
0.0	0.0	GO:0033147	negative regulation of intracellular estrogen receptor signaling pathway(GO:0033147)
0.0	0.0	GO:1904251	regulation of bile acid biosynthetic process(GO:0070857) regulation of bile acid metabolic process(GO:1904251)
0.0	0.1	GO:0034638	phosphatidylcholine catabolic process(GO:0034638)
0.0	0.0	GO:0032292	myelination in peripheral nervous system(GO:0022011) peripheral nervous system axon ensheathment(GO:0032292)
0.0	0.1	GO:0000103	sulfate assimilation(GO:0000103)
0.0	0.0	GO:0001757	somite specification(GO:0001757)
0.0	0.1	GO:0032330	regulation of chondrocyte differentiation(GO:0032330)
0.0	0.1	GO:0002069	columnar/cuboidal epithelial cell maturation(GO:0002069)
0.0	0.0	GO:0002238	response to molecule of fungal origin(GO:0002238)
0.0	0.1	GO:0010544	negative regulation of platelet activation(GO:0010544)
0.0	0.1	GO:0001561	fatty acid alpha-oxidation(GO:0001561)
0.0	0.1	GO:0090083	regulation of inclusion body assembly(GO:0090083)
0.0	0.0	GO:2000114	regulation of establishment of cell polarity(GO:2000114)
0.0	0.3	GO:0030835	negative regulation of actin filament depolymerization(GO:0030835)
0.0	0.1	GO:0010225	response to UV-C(GO:0010225)
0.0	0.2	GO:0032964	collagen biosynthetic process(GO:0032964)
0.0	0.2	GO:0045104	intermediate filament cytoskeleton organization(GO:0045104)
0.0	0.1	GO:0008228	opsonization(GO:0008228)
0.0	0.1	GO:0045039	protein import into mitochondrial inner membrane(GO:0045039)
0.0	0.0	GO:0032226	positive regulation of synaptic transmission, dopaminergic(GO:0032226)
0.0	0.0	GO:0006663	platelet activating factor biosynthetic process(GO:0006663)
0.0	0.1	GO:0050957	equilibrioception(GO:0050957)
0.0	0.1	GO:0006264	mitochondrial DNA replication(GO:0006264)
0.0	0.0	GO:0014012	peripheral nervous system axon regeneration(GO:0014012)
0.0	0.0	GO:0046449	allantoin metabolic process(GO:0000255) creatinine metabolic process(GO:0046449) cellular lactam metabolic process(GO:0072338)
0.0	0.1	GO:0043276	anoikis(GO:0043276)
0.0	0.1	GO:0018101	protein citrullination(GO:0018101)
0.0	0.0	GO:0007000	nucleolus organization(GO:0007000)
0.0	0.0	GO:0019800	peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.0	0.1	GO:0060644	mammary gland epithelial cell differentiation(GO:0060644)
0.0	0.0	GO:1900006	positive regulation of dendrite development(GO:1900006)
0.0	0.1	GO:0051883	disruption of cells of other organism involved in symbiotic interaction(GO:0051818) killing of cells in other organism involved in symbiotic interaction(GO:0051883)
0.0	0.1	GO:0009650	UV protection(GO:0009650)
0.0	0.0	GO:0003197	endocardial cushion development(GO:0003197)
0.0	0.1	GO:0030174	regulation of DNA-dependent DNA replication initiation(GO:0030174)
0.0	0.0	GO:0033314	mitotic DNA replication checkpoint(GO:0033314)
0.0	0.0	GO:0070584	mitochondrion morphogenesis(GO:0070584)
0.0	0.0	GO:0000491	small nucleolar ribonucleoprotein complex assembly(GO:0000491) box C/D snoRNP assembly(GO:0000492)
0.0	0.1	GO:0006515	misfolded or incompletely synthesized protein catabolic process(GO:0006515)
0.0	0.0	GO:0060044	negative regulation of cardiac muscle tissue growth(GO:0055022) negative regulation of cardiac muscle tissue development(GO:0055026) negative regulation of cardiac muscle cell proliferation(GO:0060044) negative regulation of heart growth(GO:0061117)
0.0	0.0	GO:0051790	short-chain fatty acid biosynthetic process(GO:0051790)
0.0	0.0	GO:0042118	endothelial cell activation(GO:0042118)
0.0	0.1	GO:0042753	positive regulation of circadian rhythm(GO:0042753)
0.0	0.1	GO:0006516	glycoprotein catabolic process(GO:0006516)
0.0	0.0	GO:0034720	histone H3-K4 demethylation(GO:0034720)
0.0	0.0	GO:0060684	epithelial-mesenchymal cell signaling(GO:0060684)
0.0	0.0	GO:0032776	DNA methylation on cytosine(GO:0032776) C-5 methylation of cytosine(GO:0090116)
0.0	0.2	GO:0000045	autophagosome assembly(GO:0000045) autophagosome organization(GO:1905037)
0.0	0.0	GO:0021535	cell migration in hindbrain(GO:0021535)
0.0	0.1	GO:0033144	negative regulation of intracellular steroid hormone receptor signaling pathway(GO:0033144)
0.0	0.0	GO:0002604	dendritic cell antigen processing and presentation(GO:0002468) regulation of dendritic cell antigen processing and presentation(GO:0002604)
0.0	0.0	GO:0060534	trachea cartilage development(GO:0060534)
0.0	0.2	GO:0035315	hair cell differentiation(GO:0035315)
0.0	0.1	GO:0060009	Sertoli cell differentiation(GO:0060008) Sertoli cell development(GO:0060009)
0.0	0.1	GO:0015884	folic acid transport(GO:0015884)
0.0	0.0	GO:0070098	chemokine-mediated signaling pathway(GO:0070098)
0.0	0.0	GO:0060996	dendritic spine development(GO:0060996)
0.0	0.0	GO:0042487	regulation of odontogenesis of dentin-containing tooth(GO:0042487)
0.0	0.0	GO:0060457	negative regulation of digestive system process(GO:0060457)
0.0	0.0	GO:0030488	tRNA methylation(GO:0030488)
0.0	0.1	GO:0042693	muscle cell fate commitment(GO:0042693)
0.0	0.1	GO:0051897	positive regulation of protein kinase B signaling(GO:0051897)
0.0	0.0	GO:0055089	fatty acid homeostasis(GO:0055089)
0.0	0.1	GO:0034644	cellular response to UV(GO:0034644)
0.0	0.0	GO:0016080	synaptic vesicle targeting(GO:0016080)
0.0	0.0	GO:0016048	detection of temperature stimulus(GO:0016048) detection of temperature stimulus involved in sensory perception(GO:0050961) detection of temperature stimulus involved in sensory perception of pain(GO:0050965)
0.0	0.1	GO:0002070	epithelial cell maturation(GO:0002070)
0.0	0.0	GO:0033137	negative regulation of peptidyl-serine phosphorylation(GO:0033137)
0.0	0.0	GO:0019919	peptidyl-arginine methylation, to asymmetrical-dimethyl arginine(GO:0019919)
0.0	0.0	GO:0045792	negative regulation of cell size(GO:0045792)
0.0	0.0	GO:0033133	regulation of glucokinase activity(GO:0033131) positive regulation of glucokinase activity(GO:0033133) regulation of hexokinase activity(GO:1903299) positive regulation of hexokinase activity(GO:1903301)
0.0	0.0	GO:0060155	platelet dense granule organization(GO:0060155)
0.0	0.0	GO:0070296	sarcoplasmic reticulum calcium ion transport(GO:0070296)
0.0	0.1	GO:0007016	cytoskeletal anchoring at plasma membrane(GO:0007016)
0.0	0.1	GO:0050926	regulation of positive chemotaxis(GO:0050926)
0.0	0.1	GO:0001893	maternal placenta development(GO:0001893)
0.0	0.1	GO:1901880	negative regulation of protein depolymerization(GO:1901880)
0.0	0.0	GO:0042574	retinal metabolic process(GO:0042574)
0.0	0.0	GO:0032236	obsolete positive regulation of calcium ion transport via store-operated calcium channel activity(GO:0032236)
0.0	0.0	GO:0035434	copper ion transmembrane transport(GO:0035434)
0.0	0.1	GO:0007320	insemination(GO:0007320)
0.0	0.0	GO:0016265	obsolete death(GO:0016265)
0.0	0.0	GO:0070208	protein heterotrimerization(GO:0070208)
0.0	0.1	GO:0018342	protein prenylation(GO:0018342) prenylation(GO:0097354)
0.0	0.0	GO:0009111	vitamin catabolic process(GO:0009111) fat-soluble vitamin catabolic process(GO:0042363)
0.0	0.1	GO:0046784	viral mRNA export from host cell nucleus(GO:0046784)
0.0	0.2	GO:0048146	positive regulation of fibroblast proliferation(GO:0048146)
0.0	0.1	GO:0006477	protein sulfation(GO:0006477)
0.0	0.0	GO:0033240	positive regulation of cellular amine metabolic process(GO:0033240)
0.0	0.0	GO:0010891	negative regulation of sequestering of triglyceride(GO:0010891)
0.0	0.0	GO:0008218	bioluminescence(GO:0008218)
0.0	0.1	GO:0046457	prostaglandin biosynthetic process(GO:0001516) prostanoid biosynthetic process(GO:0046457)
0.0	0.1	GO:0051597	response to methylmercury(GO:0051597)
0.0	0.0	GO:0007501	mesodermal cell fate specification(GO:0007501)
0.0	0.0	GO:0050872	white fat cell differentiation(GO:0050872)
0.0	0.1	GO:0030539	male genitalia development(GO:0030539)
0.0	0.0	GO:0045662	negative regulation of myoblast differentiation(GO:0045662)
0.0	0.1	GO:0019673	GDP-mannose metabolic process(GO:0019673)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.5	GO:0032588	trans-Golgi network membrane(GO:0032588)
0.1	0.3	GO:0016327	apicolateral plasma membrane(GO:0016327)
0.1	0.2	GO:0030056	hemidesmosome(GO:0030056)
0.1	0.2	GO:0031618	nuclear pericentric heterochromatin(GO:0031618)
0.0	0.3	GO:0098645	network-forming collagen trimer(GO:0098642) collagen network(GO:0098645)
0.0	0.2	GO:0042405	nuclear inclusion body(GO:0042405)
0.0	0.1	GO:0033270	paranode region of axon(GO:0033270)
0.0	0.1	GO:0005588	collagen type V trimer(GO:0005588)
0.0	0.2	GO:0031232	extrinsic component of external side of plasma membrane(GO:0031232)
0.0	0.1	GO:0048179	activin receptor complex(GO:0048179)
0.0	0.1	GO:0044216	host(GO:0018995) host cell part(GO:0033643) host intracellular part(GO:0033646) intracellular region of host(GO:0043656) host cell(GO:0043657) other organism(GO:0044215) other organism cell(GO:0044216) other organism part(GO:0044217)
0.0	0.3	GO:0005614	interstitial matrix(GO:0005614)
0.0	0.0	GO:0008282	ATP-sensitive potassium channel complex(GO:0008282)
0.0	1.0	GO:0097517	stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.0	0.3	GO:0005583	fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.0	0.0	GO:0043083	synaptic cleft(GO:0043083)
0.0	0.1	GO:0001950	obsolete plasma membrane enriched fraction(GO:0001950)
0.0	0.2	GO:0005828	kinetochore microtubule(GO:0005828)
0.0	0.1	GO:0032432	actin filament bundle(GO:0032432)
0.0	0.2	GO:0002102	podosome(GO:0002102)
0.0	0.2	GO:0005885	Arp2/3 protein complex(GO:0005885)
0.0	0.1	GO:0030061	mitochondrial crista(GO:0030061)
0.0	0.1	GO:0016942	insulin-like growth factor binding protein complex(GO:0016942) growth factor complex(GO:0036454)
0.0	0.1	GO:0005899	insulin receptor complex(GO:0005899)
0.0	0.5	GO:0005811	lipid particle(GO:0005811)
0.0	0.1	GO:0098647	collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.0	0.2	GO:0005577	fibrinogen complex(GO:0005577)
0.0	0.3	GO:0030315	T-tubule(GO:0030315)
0.0	0.1	GO:0046696	lipopolysaccharide receptor complex(GO:0046696)
0.0	0.1	GO:0042587	glycogen granule(GO:0042587)
0.0	0.1	GO:0002139	stereocilia coupling link(GO:0002139) stereocilia ankle link(GO:0002141) stereocilia ankle link complex(GO:0002142)
0.0	0.1	GO:0034673	inhibin-betaglycan-ActRII complex(GO:0034673)
0.0	0.2	GO:0042581	specific granule(GO:0042581)
0.0	0.1	GO:0031083	BLOC complex(GO:0031082) BLOC-1 complex(GO:0031083)
0.0	0.1	GO:0032809	neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.0	0.2	GO:0030128	AP-2 adaptor complex(GO:0030122) clathrin coat of endocytic vesicle(GO:0030128)
0.0	0.1	GO:0001527	microfibril(GO:0001527)
0.0	0.1	GO:0005945	6-phosphofructokinase complex(GO:0005945)
0.0	0.1	GO:0008290	F-actin capping protein complex(GO:0008290)
0.0	0.2	GO:0008328	ionotropic glutamate receptor complex(GO:0008328) neurotransmitter receptor complex(GO:0098878)
0.0	0.2	GO:0031233	intrinsic component of external side of plasma membrane(GO:0031233)
0.0	0.1	GO:0071778	obsolete WINAC complex(GO:0071778)
0.0	0.1	GO:0000347	THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.0	0.1	GO:0043260	laminin-11 complex(GO:0043260)
0.0	0.1	GO:0030870	Mre11 complex(GO:0030870)
0.0	0.1	GO:0030132	clathrin coat of coated pit(GO:0030132)
0.0	0.1	GO:0031092	platelet alpha granule membrane(GO:0031092)
0.0	0.1	GO:0033268	node of Ranvier(GO:0033268)
0.0	0.1	GO:0031143	pseudopodium(GO:0031143)
0.0	0.1	GO:0016442	RISC complex(GO:0016442) RNAi effector complex(GO:0031332)
0.0	0.0	GO:0071001	U4/U6 snRNP(GO:0071001)
0.0	0.1	GO:0031430	M band(GO:0031430)
0.0	0.1	GO:0045281	mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)(GO:0005749) succinate dehydrogenase complex (ubiquinone)(GO:0045257) respiratory chain complex II(GO:0045273) succinate dehydrogenase complex(GO:0045281) fumarate reductase complex(GO:0045283)
0.0	0.1	GO:0001520	outer dense fiber(GO:0001520) sperm flagellum(GO:0036126)
0.0	0.1	GO:0042719	mitochondrial intermembrane space protein transporter complex(GO:0042719)
0.0	0.0	GO:0030934	anchoring collagen complex(GO:0030934)
0.0	0.0	GO:0005862	muscle thin filament tropomyosin(GO:0005862)
0.0	0.1	GO:0005916	fascia adherens(GO:0005916)
0.0	0.0	GO:0005826	actomyosin contractile ring(GO:0005826)
0.0	0.6	GO:0000118	histone deacetylase complex(GO:0000118)
0.0	0.1	GO:0005865	striated muscle thin filament(GO:0005865)
0.0	0.1	GO:0000015	phosphopyruvate hydratase complex(GO:0000015)
0.0	0.0	GO:0071664	catenin-TCF7L2 complex(GO:0071664)
0.0	0.0	GO:0031045	dense core granule(GO:0031045)
0.0	0.0	GO:0071062	alphav-beta3 integrin-vitronectin complex(GO:0071062)
0.0	1.1	GO:0030016	myofibril(GO:0030016)
0.0	0.2	GO:0005581	collagen trimer(GO:0005581)
0.0	0.1	GO:0032389	MutLalpha complex(GO:0032389)
0.0	0.1	GO:0000800	lateral element(GO:0000800)
0.0	0.5	GO:0005905	clathrin-coated pit(GO:0005905)
0.0	0.1	GO:0008385	IkappaB kinase complex(GO:0008385)
0.0	0.3	GO:0017053	transcriptional repressor complex(GO:0017053)
0.0	0.0	GO:0043240	Fanconi anaemia nuclear complex(GO:0043240)
0.0	0.1	GO:0031312	extrinsic component of organelle membrane(GO:0031312)
0.0	0.0	GO:0030904	retromer complex(GO:0030904)
0.0	0.1	GO:0033017	sarcoplasmic reticulum membrane(GO:0033017)
0.0	0.1	GO:0001739	sex chromatin(GO:0001739)
0.0	0.2	GO:0030057	desmosome(GO:0030057)
0.0	0.1	GO:0002080	acrosomal membrane(GO:0002080)
0.0	0.0	GO:0071547	piP-body(GO:0071547)
0.0	0.3	GO:0008305	integrin complex(GO:0008305) protein complex involved in cell adhesion(GO:0098636)
0.0	0.0	GO:0000124	SAGA complex(GO:0000124)
0.0	0.2	GO:0001750	photoreceptor outer segment(GO:0001750)
0.0	0.1	GO:0042599	lamellar body(GO:0042599)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	0.5	GO:0051371	muscle alpha-actinin binding(GO:0051371)
0.1	0.5	GO:0005010	insulin-like growth factor-activated receptor activity(GO:0005010)
0.1	0.4	GO:0000978	RNA polymerase II core promoter proximal region sequence-specific DNA binding(GO:0000978) core promoter proximal region sequence-specific DNA binding(GO:0000987) core promoter proximal region DNA binding(GO:0001159)
0.1	0.3	GO:0005173	stem cell factor receptor binding(GO:0005173)
0.1	0.3	GO:0019834	phospholipase A2 inhibitor activity(GO:0019834)
0.1	0.3	GO:0005006	epidermal growth factor-activated receptor activity(GO:0005006)
0.1	0.3	GO:0030297	transmembrane receptor protein tyrosine kinase activator activity(GO:0030297)
0.1	0.2	GO:0045236	CXCR chemokine receptor binding(GO:0045236)
0.1	0.2	GO:0004948	calcitonin receptor activity(GO:0004948)
0.1	0.3	GO:0048406	nerve growth factor binding(GO:0048406)
0.1	0.3	GO:0042805	actinin binding(GO:0042805)
0.1	0.2	GO:0050508	glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0050508)
0.1	0.2	GO:0005432	calcium:sodium antiporter activity(GO:0005432)
0.1	0.4	GO:0005110	frizzled-2 binding(GO:0005110)
0.1	0.3	GO:0051637	obsolete Gram-positive bacterial cell surface binding(GO:0051637)
0.1	0.2	GO:0017128	phospholipid scramblase activity(GO:0017128)
0.0	0.2	GO:0004597	peptide-aspartate beta-dioxygenase activity(GO:0004597)
0.0	0.1	GO:0008321	Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.0	0.1	GO:0002162	dystroglycan binding(GO:0002162)
0.0	0.1	GO:0050682	AF-2 domain binding(GO:0050682)
0.0	0.1	GO:0005017	platelet-derived growth factor-activated receptor activity(GO:0005017)
0.0	0.1	GO:0004142	diacylglycerol cholinephosphotransferase activity(GO:0004142)
0.0	0.2	GO:0005078	MAP-kinase scaffold activity(GO:0005078)
0.0	0.3	GO:0008046	axon guidance receptor activity(GO:0008046)
0.0	0.1	GO:0042799	histone methyltransferase activity (H4-K20 specific)(GO:0042799)
0.0	0.1	GO:0043515	kinetochore binding(GO:0043515)
0.0	0.3	GO:0017166	vinculin binding(GO:0017166)
0.0	0.1	GO:0015183	L-aspartate transmembrane transporter activity(GO:0015183)
0.0	0.1	GO:0001758	retinal dehydrogenase activity(GO:0001758)
0.0	0.3	GO:0015220	choline transmembrane transporter activity(GO:0015220)
0.0	0.2	GO:0048027	mRNA 5'-UTR binding(GO:0048027)
0.0	0.4	GO:0015245	fatty acid transporter activity(GO:0015245)
0.0	0.1	GO:0070644	vitamin D response element binding(GO:0070644)
0.0	0.3	GO:0004908	interleukin-1 receptor activity(GO:0004908)
0.0	0.4	GO:0048407	platelet-derived growth factor binding(GO:0048407)
0.0	0.1	GO:0004768	stearoyl-CoA 9-desaturase activity(GO:0004768) acyl-CoA desaturase activity(GO:0016215)
0.0	0.6	GO:0005523	tropomyosin binding(GO:0005523)
0.0	0.2	GO:0008266	poly(U) RNA binding(GO:0008266)
0.0	0.2	GO:0004862	cAMP-dependent protein kinase inhibitor activity(GO:0004862)
0.0	0.2	GO:0000293	ferric-chelate reductase activity(GO:0000293)
0.0	0.1	GO:0003680	AT DNA binding(GO:0003680)
0.0	0.1	GO:0004157	dihydropyrimidinase activity(GO:0004157)
0.0	0.1	GO:0030215	semaphorin receptor binding(GO:0030215)
0.0	0.1	GO:0004470	malic enzyme activity(GO:0004470)
0.0	0.1	GO:0031995	insulin-like growth factor II binding(GO:0031995)
0.0	0.0	GO:0070273	phosphatidylinositol-4-phosphate binding(GO:0070273)
0.0	0.1	GO:0005294	neutral L-amino acid secondary active transmembrane transporter activity(GO:0005294)
0.0	0.3	GO:0046965	retinoid X receptor binding(GO:0046965)
0.0	0.1	GO:0048495	Roundabout binding(GO:0048495)
0.0	0.3	GO:0047372	acylglycerol lipase activity(GO:0047372)
0.0	0.2	GO:0009374	biotin binding(GO:0009374)
0.0	0.1	GO:0033130	acetylcholine receptor binding(GO:0033130)
0.0	0.1	GO:0045545	syndecan binding(GO:0045545)
0.0	0.2	GO:0031435	mitogen-activated protein kinase kinase kinase binding(GO:0031435)
0.0	0.1	GO:0016361	activin receptor activity, type I(GO:0016361)
0.0	0.2	GO:0017080	sodium channel regulator activity(GO:0017080)
0.0	0.4	GO:0004065	arylsulfatase activity(GO:0004065)
0.0	0.1	GO:0070052	collagen V binding(GO:0070052)
0.0	0.1	GO:0004117	calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117)
0.0	0.1	GO:0016717	oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water(GO:0016717)
0.0	0.1	GO:0042056	chemoattractant activity(GO:0042056)
0.0	0.2	GO:0004716	receptor signaling protein tyrosine kinase activity(GO:0004716)
0.0	0.2	GO:0050656	3'-phosphoadenosine 5'-phosphosulfate binding(GO:0050656)
0.0	0.3	GO:0051010	microtubule plus-end binding(GO:0051010)
0.0	0.1	GO:0015016	[heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
0.0	0.0	GO:0031957	very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.0	0.2	GO:0030492	hemoglobin binding(GO:0030492)
0.0	0.1	GO:0042808	obsolete neuronal Cdc2-like kinase binding(GO:0042808)
0.0	0.1	GO:0050501	hyaluronan synthase activity(GO:0050501)
0.0	0.1	GO:0004720	protein-lysine 6-oxidase activity(GO:0004720)
0.0	0.6	GO:0050840	extracellular matrix binding(GO:0050840)
0.0	0.1	GO:0008190	eukaryotic initiation factor 4E binding(GO:0008190)
0.0	0.2	GO:0005112	Notch binding(GO:0005112)
0.0	0.1	GO:0004758	serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
0.0	0.1	GO:0010314	phosphatidylinositol-5-phosphate binding(GO:0010314)
0.0	0.2	GO:0005172	vascular endothelial growth factor receptor binding(GO:0005172)
0.0	0.1	GO:0016715	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen(GO:0016715)
0.0	0.1	GO:0005275	amine transmembrane transporter activity(GO:0005275)
0.0	0.1	GO:0005534	galactose binding(GO:0005534)
0.0	0.1	GO:0034186	apolipoprotein A-I binding(GO:0034186)
0.0	0.1	GO:0070290	N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.0	0.1	GO:0032052	bile acid binding(GO:0032052)
0.0	0.1	GO:0046975	histone methyltransferase activity (H3-K36 specific)(GO:0046975)
0.0	0.2	GO:0019992	diacylglycerol binding(GO:0019992)
0.0	0.1	GO:0033743	peptide-methionine (R)-S-oxide reductase activity(GO:0033743)
0.0	0.1	GO:0004045	aminoacyl-tRNA hydrolase activity(GO:0004045)
0.0	0.1	GO:0004321	fatty-acyl-CoA synthase activity(GO:0004321)
0.0	0.1	GO:0016509	long-chain-3-hydroxyacyl-CoA dehydrogenase activity(GO:0016509)
0.0	0.3	GO:0043498	obsolete cell surface binding(GO:0043498)
0.0	0.5	GO:0031683	G-protein beta/gamma-subunit complex binding(GO:0031683)
0.0	0.1	GO:0017162	aryl hydrocarbon receptor binding(GO:0017162)
0.0	0.0	GO:0004075	biotin carboxylase activity(GO:0004075)
0.0	0.1	GO:0005499	vitamin D binding(GO:0005499)
0.0	0.1	GO:0048039	ubiquinone binding(GO:0048039)
0.0	0.2	GO:0030506	ankyrin binding(GO:0030506)
0.0	0.1	GO:0015174	basic amino acid transmembrane transporter activity(GO:0015174)
0.0	0.1	GO:0070700	BMP receptor binding(GO:0070700)
0.0	0.3	GO:0004143	diacylglycerol kinase activity(GO:0004143)
0.0	0.1	GO:0004791	thioredoxin-disulfide reductase activity(GO:0004791)
0.0	0.2	GO:0003706	obsolete ligand-regulated transcription factor activity(GO:0003706)
0.0	0.3	GO:0004653	polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.0	0.1	GO:0004937	alpha1-adrenergic receptor activity(GO:0004937)
0.0	0.1	GO:0044548	S100 protein binding(GO:0044548)
0.0	0.1	GO:0032190	acrosin binding(GO:0032190)
0.0	0.2	GO:0016641	oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor(GO:0016641)
0.0	0.1	GO:0016623	oxidoreductase activity, acting on the aldehyde or oxo group of donors, oxygen as acceptor(GO:0016623)
0.0	0.1	GO:0004969	histamine receptor activity(GO:0004969)
0.0	0.1	GO:0003956	NAD(P)+-protein-arginine ADP-ribosyltransferase activity(GO:0003956)
0.0	0.1	GO:0003872	6-phosphofructokinase activity(GO:0003872)
0.0	0.2	GO:0016813	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
0.0	0.1	GO:0045499	chemorepellent activity(GO:0045499)
0.0	0.1	GO:0004515	nicotinamide-nucleotide adenylyltransferase activity(GO:0000309) nicotinate-nucleotide adenylyltransferase activity(GO:0004515)
0.0	0.1	GO:0004430	1-phosphatidylinositol 4-kinase activity(GO:0004430)
0.0	0.1	GO:0004370	glycerol kinase activity(GO:0004370)
0.0	0.1	GO:0008401	retinoic acid 4-hydroxylase activity(GO:0008401)
0.0	0.1	GO:0030898	actin-dependent ATPase activity(GO:0030898)
0.0	0.1	GO:0050998	nitric-oxide synthase binding(GO:0050998)
0.0	0.1	GO:0008898	S-adenosylmethionine-homocysteine S-methyltransferase activity(GO:0008898)
0.0	0.1	GO:0004300	enoyl-CoA hydratase activity(GO:0004300)
0.0	0.1	GO:0003886	DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.0	0.3	GO:0004012	phospholipid-translocating ATPase activity(GO:0004012)
0.0	0.0	GO:0032450	maltose alpha-glucosidase activity(GO:0032450)
0.0	0.1	GO:0045569	TRAIL binding(GO:0045569)
0.0	0.1	GO:0005148	prolactin receptor binding(GO:0005148)
0.0	0.0	GO:0001849	complement component C1q binding(GO:0001849)
0.0	0.1	GO:0048038	quinone binding(GO:0048038)
0.0	0.1	GO:0046912	transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
0.0	0.0	GO:0016972	thiol oxidase activity(GO:0016972)
0.0	0.1	GO:0017112	Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0	0.1	GO:0015277	kainate selective glutamate receptor activity(GO:0015277)
0.0	0.1	GO:0016565	obsolete general transcriptional repressor activity(GO:0016565)
0.0	0.0	GO:0042289	MHC class II protein binding(GO:0042289)
0.0	0.0	GO:0004167	dopachrome isomerase activity(GO:0004167)
0.0	0.1	GO:0032407	MutSalpha complex binding(GO:0032407)
0.0	0.1	GO:0003691	double-stranded telomeric DNA binding(GO:0003691)
0.0	0.1	GO:0071617	1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841) lysophosphatidic acid acyltransferase activity(GO:0042171) lysophospholipid acyltransferase activity(GO:0071617)
0.0	0.1	GO:0004128	cytochrome-b5 reductase activity, acting on NAD(P)H(GO:0004128)
0.0	0.1	GO:0005143	interleukin-12 receptor binding(GO:0005143)
0.0	0.0	GO:0034584	piRNA binding(GO:0034584)
0.0	0.1	GO:0005315	inorganic phosphate transmembrane transporter activity(GO:0005315)
0.0	0.1	GO:0047961	glycine N-acyltransferase activity(GO:0047961)
0.0	0.1	GO:0051380	norepinephrine binding(GO:0051380)
0.0	0.0	GO:0030548	acetylcholine receptor regulator activity(GO:0030548) neurotransmitter receptor regulator activity(GO:0099602)
0.0	0.0	GO:0016653	oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor(GO:0016653)
0.0	0.0	GO:0032554	purine deoxyribonucleotide binding(GO:0032554) adenyl deoxyribonucleotide binding(GO:0032558)
0.0	0.1	GO:0046790	virion binding(GO:0046790)
0.0	0.1	GO:0004185	serine-type carboxypeptidase activity(GO:0004185)
0.0	0.0	GO:0031994	insulin-like growth factor I binding(GO:0031994)
0.0	0.1	GO:0004634	phosphopyruvate hydratase activity(GO:0004634)
0.0	0.0	GO:0042978	ornithine decarboxylase activator activity(GO:0042978)
0.0	0.2	GO:0005104	fibroblast growth factor receptor binding(GO:0005104)
0.0	0.1	GO:0004859	phospholipase inhibitor activity(GO:0004859)
0.0	0.1	GO:0035252	UDP-xylosyltransferase activity(GO:0035252) xylosyltransferase activity(GO:0042285)
0.0	0.1	GO:0008242	omega peptidase activity(GO:0008242)
0.0	0.1	GO:0008159	obsolete positive transcription elongation factor activity(GO:0008159)
0.0	0.1	GO:0032452	histone demethylase activity(GO:0032452)
0.0	0.0	GO:0070576	vitamin D 24-hydroxylase activity(GO:0070576)
0.0	0.0	GO:0051636	obsolete Gram-negative bacterial cell surface binding(GO:0051636)
0.0	0.1	GO:0015368	calcium, potassium:sodium antiporter activity(GO:0008273) calcium:cation antiporter activity(GO:0015368)
0.0	0.6	GO:0008009	chemokine activity(GO:0008009)
0.0	0.1	GO:0047498	calcium-dependent phospholipase A2 activity(GO:0047498)
0.0	0.1	GO:0030515	snoRNA binding(GO:0030515)
0.0	0.1	GO:0008253	5'-nucleotidase activity(GO:0008253)
0.0	0.0	GO:0001875	lipopolysaccharide receptor activity(GO:0001875)
0.0	0.1	GO:0008318	protein prenyltransferase activity(GO:0008318)
0.0	0.3	GO:0004181	metallocarboxypeptidase activity(GO:0004181)
0.0	0.0	GO:0004322	ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.0	0.2	GO:0005242	inward rectifier potassium channel activity(GO:0005242)
0.0	0.0	GO:0031544	procollagen-proline 3-dioxygenase activity(GO:0019797) peptidyl-proline 3-dioxygenase activity(GO:0031544)
0.0	0.0	GO:0008113	peptide-methionine (S)-S-oxide reductase activity(GO:0008113)
0.0	0.0	GO:0019763	immunoglobulin receptor activity(GO:0019763)
0.0	0.0	GO:0001515	opioid peptide activity(GO:0001515)
0.0	0.1	GO:0004035	alkaline phosphatase activity(GO:0004035)
0.0	0.6	GO:0051015	actin filament binding(GO:0051015)
0.0	0.1	GO:0004030	aldehyde dehydrogenase [NAD(P)+] activity(GO:0004030)
0.0	0.0	GO:0004144	diacylglycerol O-acyltransferase activity(GO:0004144)
0.0	0.0	GO:0004687	myosin light chain kinase activity(GO:0004687)
0.0	0.1	GO:0016944	obsolete RNA polymerase II transcription elongation factor activity(GO:0016944)
0.0	0.0	GO:0004516	nicotinate phosphoribosyltransferase activity(GO:0004516)
0.0	0.1	GO:0047429	nucleoside-triphosphate diphosphatase activity(GO:0047429)
0.0	0.2	GO:0005247	voltage-gated chloride channel activity(GO:0005247)
0.0	0.0	GO:0004849	uridine kinase activity(GO:0004849)
0.0	0.0	GO:0003846	2-acylglycerol O-acyltransferase activity(GO:0003846)
0.0	0.0	GO:0050253	retinyl-palmitate esterase activity(GO:0050253)
0.0	0.0	GO:0001846	opsonin binding(GO:0001846)
0.0	0.1	GO:0042605	peptide antigen binding(GO:0042605)
0.0	0.0	GO:0033765	steroid dehydrogenase activity, acting on the CH-CH group of donors(GO:0033765)
0.0	0.0	GO:0042577	lipid phosphatase activity(GO:0042577)
0.0	0.0	GO:0047184	1-acylglycerophosphocholine O-acyltransferase activity(GO:0047184)
0.0	0.0	GO:0070579	methylcytosine dioxygenase activity(GO:0070579)
0.0	0.1	GO:0050780	dopamine receptor binding(GO:0050780)
0.0	0.2	GO:0005212	structural constituent of eye lens(GO:0005212)
0.0	0.0	GO:0070891	lipoteichoic acid binding(GO:0070891)
0.0	0.1	GO:0005536	glucose binding(GO:0005536)
0.0	0.0	GO:0016909	JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.0	0.0	GO:0004525	ribonuclease III activity(GO:0004525) double-stranded RNA-specific ribonuclease activity(GO:0032296)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.3	PID FAK PATHWAY	Signaling events mediated by focal adhesion kinase
0.0	0.1	PID NEPHRIN NEPH1 PATHWAY	Nephrin/Neph1 signaling in the kidney podocyte
0.0	0.6	PID INTEGRIN5 PATHWAY	Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.0	0.2	ST TYPE I INTERFERON PATHWAY	Type I Interferon (alpha/beta IFN) Pathway
0.0	0.5	PID ERBB NETWORK PATHWAY	ErbB receptor signaling network
0.0	0.3	SA G2 AND M PHASES	Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.0	0.1	PID P38 MK2 PATHWAY	p38 signaling mediated by MAPKAP kinases
0.0	0.2	PID AJDISS 2PATHWAY	Posttranslational regulation of adherens junction stability and dissassembly
0.0	1.0	NABA COLLAGENS	Genes encoding collagen proteins
0.0	0.5	ST GA12 PATHWAY	G alpha 12 Pathway
0.0	0.0	PID ANGIOPOIETIN RECEPTOR PATHWAY	Angiopoietin receptor Tie2-mediated signaling
0.0	0.5	PID INTEGRIN A9B1 PATHWAY	Alpha9 beta1 integrin signaling events
0.0	0.4	PID S1P S1P2 PATHWAY	S1P2 pathway
0.0	0.3	PID CIRCADIAN PATHWAY	Circadian rhythm pathway
0.0	0.0	ST T CELL SIGNAL TRANSDUCTION	T Cell Signal Transduction
0.0	0.1	PID NETRIN PATHWAY	Netrin-mediated signaling events
0.0	0.2	PID IFNG PATHWAY	IFN-gamma pathway
0.0	0.1	PID PDGFRA PATHWAY	PDGFR-alpha signaling pathway
0.0	0.1	PID SMAD2 3PATHWAY	Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0	0.0	PID SHP2 PATHWAY	SHP2 signaling
0.0	0.1	PID PTP1B PATHWAY	Signaling events mediated by PTP1B
0.0	0.4	PID P38 ALPHA BETA DOWNSTREAM PATHWAY	Signaling mediated by p38-alpha and p38-beta
0.0	0.6	PID TAP63 PATHWAY	Validated transcriptional targets of TAp63 isoforms
0.0	0.2	PID SYNDECAN 4 PATHWAY	Syndecan-4-mediated signaling events
0.0	0.1	PID NECTIN PATHWAY	Nectin adhesion pathway
0.0	0.3	PID UPA UPAR PATHWAY	Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.1	REACTOME PLC BETA MEDIATED EVENTS	Genes involved in PLC beta mediated events
0.1	0.1	REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE	Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.0	0.4	REACTOME ROLE OF DCC IN REGULATING APOPTOSIS	Genes involved in Role of DCC in regulating apoptosis
0.0	0.9	REACTOME SMOOTH MUSCLE CONTRACTION	Genes involved in Smooth Muscle Contraction
0.0	0.1	REACTOME THROMBOXANE SIGNALLING THROUGH TP RECEPTOR	Genes involved in Thromboxane signalling through TP receptor
0.0	0.4	REACTOME GAP JUNCTION DEGRADATION	Genes involved in Gap junction degradation
0.0	0.3	REACTOME VEGF LIGAND RECEPTOR INTERACTIONS	Genes involved in VEGF ligand-receptor interactions
0.0	0.2	REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK	Genes involved in Negative regulation of the PI3K/AKT network
0.0	0.0	REACTOME CYTOKINE SIGNALING IN IMMUNE SYSTEM	Genes involved in Cytokine Signaling in Immune system
0.0	0.2	REACTOME ADP SIGNALLING THROUGH P2RY12	Genes involved in ADP signalling through P2Y purinoceptor 12
0.0	0.4	REACTOME OTHER SEMAPHORIN INTERACTIONS	Genes involved in Other semaphorin interactions
0.0	0.3	REACTOME SIGNALING BY ACTIVATED POINT MUTANTS OF FGFR1	Genes involved in Signaling by activated point mutants of FGFR1
0.0	0.4	REACTOME PRE NOTCH PROCESSING IN GOLGI	Genes involved in Pre-NOTCH Processing in Golgi
0.0	0.2	REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR	Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.0	0.0	REACTOME ALPHA LINOLENIC ACID ALA METABOLISM	Genes involved in alpha-linolenic acid (ALA) metabolism
0.0	0.2	REACTOME PI3K AKT ACTIVATION	Genes involved in PI3K/AKT activation
0.0	0.1	REACTOME PD1 SIGNALING	Genes involved in PD-1 signaling
0.0	0.2	REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE	Genes involved in Synthesis of PIPs at the late endosome membrane
0.0	0.2	REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING	Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.0	0.2	REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS	Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0	0.3	REACTOME THE ACTIVATION OF ARYLSULFATASES	Genes involved in The activation of arylsulfatases
0.0	0.2	REACTOME PURINE CATABOLISM	Genes involved in Purine catabolism
0.0	0.2	REACTOME CRMPS IN SEMA3A SIGNALING	Genes involved in CRMPs in Sema3A signaling
0.0	0.0	REACTOME DESTABILIZATION OF MRNA BY TRISTETRAPROLIN TTP	Genes involved in Destabilization of mRNA by Tristetraprolin (TTP)
0.0	0.4	REACTOME INTERACTION BETWEEN L1 AND ANKYRINS	Genes involved in Interaction between L1 and Ankyrins
0.0	0.6	REACTOME PI3K EVENTS IN ERBB2 SIGNALING	Genes involved in PI3K events in ERBB2 signaling
0.0	1.0	REACTOME COLLAGEN FORMATION	Genes involved in Collagen formation
0.0	0.5	REACTOME MYOGENESIS	Genes involved in Myogenesis
0.0	0.1	REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS	Genes involved in Ionotropic activity of Kainate Receptors
0.0	0.0	REACTOME DESTABILIZATION OF MRNA BY BRF1	Genes involved in Destabilization of mRNA by Butyrate Response Factor 1 (BRF1)
0.0	0.0	REACTOME BILE ACID AND BILE SALT METABOLISM	Genes involved in Bile acid and bile salt metabolism
0.0	0.3	REACTOME SYNTHESIS OF PC	Genes involved in Synthesis of PC
0.0	0.0	REACTOME DESTABILIZATION OF MRNA BY AUF1 HNRNP D0	Genes involved in Destabilization of mRNA by AUF1 (hnRNP D0)
0.0	0.3	REACTOME PRE NOTCH TRANSCRIPTION AND TRANSLATION	Genes involved in Pre-NOTCH Transcription and Translation
0.0	0.2	REACTOME REGULATION OF KIT SIGNALING	Genes involved in Regulation of KIT signaling
0.0	0.3	REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS	Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0	0.2	REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION	Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.0	0.4	REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS	Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.0	0.1	REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE	Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.0	0.2	REACTOME DCC MEDIATED ATTRACTIVE SIGNALING	Genes involved in DCC mediated attractive signaling
0.0	0.2	REACTOME HDL MEDIATED LIPID TRANSPORT	Genes involved in HDL-mediated lipid transport
0.0	0.0	REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE	Genes involved in Translocation of ZAP-70 to Immunological synapse
0.0	0.0	REACTOME REMOVAL OF THE FLAP INTERMEDIATE FROM THE C STRAND	Genes involved in Removal of the Flap Intermediate from the C-strand
0.0	0.0	REACTOME PROSTACYCLIN SIGNALLING THROUGH PROSTACYCLIN RECEPTOR	Genes involved in Prostacyclin signalling through prostacyclin receptor
0.0	0.0	REACTOME TRAF6 MEDIATED NFKB ACTIVATION	Genes involved in TRAF6 mediated NF-kB activation
0.0	0.1	REACTOME ANDROGEN BIOSYNTHESIS	Genes involved in Androgen biosynthesis
0.0	0.2	REACTOME PLATELET CALCIUM HOMEOSTASIS	Genes involved in Platelet calcium homeostasis
0.0	0.2	REACTOME RNA POL III TRANSCRIPTION TERMINATION	Genes involved in RNA Polymerase III Transcription Termination
0.0	0.2	REACTOME ADHERENS JUNCTIONS INTERACTIONS	Genes involved in Adherens junctions interactions
0.0	0.2	REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS	Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.0	0.2	REACTOME SYNTHESIS OF PA	Genes involved in Synthesis of PA