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ENCODE: H3K4me1 ChIP-Seq of primary human cells
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Results for SIN3A_CHD1

Z-value: 1.02

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Transcription factors associated with SIN3A_CHD1

Gene Symbol Gene ID Gene Info
SIN3A
ENSG00000169375.11 SIN3 transcription regulator family member A
CHD1
ENSG00000153922.6 chromodomain helicase DNA binding protein 1

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE Gene Distance Association probability Pearson corr. coef. P-value Plot
chr5_98251278_98251429CHD1108870.2022990.742.4e-02Click!
chr5_98254524_98254675CHD176410.2126080.674.8e-02Click!
chr5_98262951_98263102CHD17860.672821-0.655.9e-02Click!
chr5_98247552_98247756CHD1145860.1936430.608.4e-02Click!
chr5_98250243_98250394CHD1119220.1997490.541.4e-01Click!
chr15_75761109_75761260SIN3A130010.1734500.781.2e-02Click!
chr15_75744674_75744875SIN3A6870.684485-0.617.9e-02Click!
chr15_75724560_75724777SIN3A192580.1522480.618.3e-02Click!
chr15_75719269_75719420SIN3A245820.138895-0.561.2e-01Click!
chr15_75761353_75761612SIN3A132990.1728450.531.4e-01Click!

Activity of the SIN3A_CHD1 motif across conditions

Conditions sorted by the z-value of the SIN3A_CHD1 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE) Target Score Top associated gene Gene Info Distance of CRE to TSS CRE/Gene association probability
chr9_69786015_69786709 1.34 IGKV1OR-2
 immunoglobulin kappa variable 1/OR-2 (pseudogene)
 8409
 0.25
chr17_1132183_1132576 0.55 ABR
 active BCR-related
 81
 0.97
chr1_220863452_220864325 0.50 C1orf115
 chromosome 1 open reading frame 115
 701
 0.71
chr16_49315668_49315968 0.50 CBLN1
 cerebellin 1 precursor
 76
 0.98
chr8_140716343_140716851 0.47 KCNK9
 potassium channel, subfamily K, member 9
 1298
 0.63
chr6_1611321_1611696 0.47 FOXC1
 forkhead box C1
 827
 0.76
chr4_170192393_170192771 0.46 SH3RF1
 SH3 domain containing ring finger 1
 326
 0.93
chr1_1475615_1475901 0.46 TMEM240
 transmembrane protein 240
 21
 0.96
chrX_68724102_68724531 0.42 ENSG00000264604
 .
 232
 0.85
chrX_153095505_153095958 0.41 PDZD4
 PDZ domain containing 4
 82
 0.94
chr19_14168091_14168390 0.40 PALM3
 paralemmin 3
 171
 0.89
chr2_42795325_42795726 0.39 MTA3
 metastasis associated 1 family, member 3
 132
 0.97
chr5_175299080_175299718 0.39 CPLX2
 complexin 2
 414
 0.87
chr2_176972649_176972909 0.39 ENSG00000216193
 .
 592
 0.39
chr1_38511967_38512267 0.38 POU3F1
 POU class 3 homeobox 1
 333
 0.86
chr7_128431078_128431544 0.37 CCDC136
 coiled-coil domain containing 136
 153
 0.93
chr7_145812958_145813349 0.37 CNTNAP2
 contactin associated protein-like 2
 300
 0.93
chr8_81477973_81478412 0.37 ENSG00000223327
 .
 19816
 0.2
chr19_52192320_52192671 0.36 ENSG00000207550
 .
 3370
 0.12
chr7_129419053_129419592 0.36 ENSG00000207691
 .
 4468
 0.17
chr19_1513130_1513873 0.35 ADAMTSL5
 ADAMTS-like 5
 313
 0.73
chr1_41130861_41131209 0.35 RIMS3
 regulating synaptic membrane exocytosis 3
 82
 0.97
chr17_71641352_71641596 0.35 SDK2
 sidekick cell adhesion molecule 2
 1246
 0.51
chr6_1611903_1612454 0.35 FOXC1
 forkhead box C1
 1497
 0.56
chr19_1164693_1164844 0.34 SBNO2
 strawberry notch homolog 2 (Drosophila)
 4174
 0.14
chr19_15491045_15491543 0.34 AKAP8
 A kinase (PRKA) anchor protein 8
 691
 0.51
chr10_81206187_81206604 0.34 ZCCHC24
 zinc finger, CCHC domain containing 24
 1012
 0.58
chr12_662501_663191 0.32 B4GALNT3
 beta-1,4-N-acetyl-galactosaminyl transferase 3
 10547
 0.16
chr9_103235830_103236309 0.32 TMEFF1
 transmembrane protein with EGF-like and two follistatin-like domains 1
 674
 0.71
chr7_1704828_1705261 0.31 ELFN1
 extracellular leucine-rich repeat and fibronectin type III domain containing 1
 22711
 0.17
chr8_145012318_145012709 0.30 PLEC
 plectin
 1245
 0.31
chr17_37729625_37730222 0.30 ENSG00000222777
 .
 27426
 0.12
chr9_14315059_14315375 0.29 NFIB
 nuclear factor I/B
 636
 0.73
chr14_24837858_24838637 0.29 NFATC4
 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4
 41
 0.94
chr19_8260319_8260582 0.29 CERS4
 ceramide synthase 4
 11170
 0.16
chr1_895413_895840 0.29 KLHL17
 kelch-like family member 17
 341
 0.68
chr6_41993885_41994069 0.29 ENSG00000206875
 .
 7725
 0.16
chr17_33787552_33787703 0.29 SLFN13
 schlafen family member 13
 11771
 0.12
chr19_7989733_7990535 0.27 CTD-3193O13.8
752
 0.29
chr8_144955877_144956171 0.27 EPPK1
 epiplakin 1
 3392
 0.13
chr17_76875045_76875748 0.27 TIMP2
 TIMP metallopeptidase inhibitor 2
 5164
 0.16
chr14_56683953_56684174 0.27 PELI2
 pellino E3 ubiquitin protein ligase family member 2
 98236
 0.08
chr12_80083776_80084245 0.27 PAWR
 PRKC, apoptosis, WT1, regulator
 150
 0.97
chr2_43361384_43361969 0.26 ENSG00000207087
 .
 43044
 0.18
chr3_137490047_137490281 0.26 SOX14
 SRY (sex determining region Y)-box 14
 6585
 0.32
chr6_35181746_35182466 0.26 SCUBE3
 signal peptide, CUB domain, EGF-like 3
 84
 0.97
chr22_39417441_39417875 0.26 APOBEC3D
 apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3D
 201
 0.89
chr18_76740387_76741175 0.26 SALL3
 spalt-like transcription factor 3
 506
 0.87
chr5_79365725_79365962 0.26 CTD-2201I18.1
12384
 0.2
chr17_80398931_80399097 0.26 C17orf62
 chromosome 17 open reading frame 62
 3390
 0.11
chr14_103986978_103987655 0.26 CKB
 creatine kinase, brain
 122
 0.92
chrX_135849318_135849469 0.25 ARHGEF6
 Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6
 109
 0.97
chr6_43738525_43738880 0.25 VEGFA
 vascular endothelial growth factor A
 118
 0.78
chr2_219846310_219846631 0.25 FEV
 FEV (ETS oncogene family)
 3909
 0.11
chr19_709223_709862 0.25 PALM
 paralemmin
 441
 0.7
chr21_37502666_37502817 0.25 AP000688.14
3803
 0.15
chr17_1613463_1614162 0.25 TLCD2
 TLC domain containing 2
 80
 0.94
chr4_2061713_2062092 0.25 NAT8L
 N-acetyltransferase 8-like (GCN5-related, putative)
 363
 0.84
chr2_135018956_135019266 0.24 MGAT5
 mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase
 7281
 0.27
chr2_63281096_63281304 0.24 OTX1
 orthodenticle homeobox 1
 3263
 0.29
chr14_65213142_65213375 0.24 PLEKHG3
 pleckstrin homology domain containing, family G (with RhoGef domain) member 3
 8505
 0.21
chrX_53349333_53349573 0.24 IQSEC2
 IQ motif and Sec7 domain 2
 1069
 0.48
chr11_48002134_48002405 0.24 PTPRJ
 protein tyrosine phosphatase, receptor type, J
 10
 0.98
chr1_9303878_9304029 0.24 H6PD
 hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase)
 4050
 0.23
chr1_47904813_47905194 0.24 FOXD2
 forkhead box D2
 3314
 0.19
chr1_2986226_2986879 0.23 PRDM16
 PR domain containing 16
 777
 0.57
chr16_87022731_87022882 0.23 RP11-899L11.3
226715
 0.02
chr2_175869706_175870142 0.23 CHN1
 chimerin 1
 30
 0.97
chr6_138752539_138752911 0.23 ENSG00000266555
 .
 3706
 0.25
chr7_139960445_139960596 0.23 ENSG00000199283
 .
 18850
 0.17
chr2_239139883_239140304 0.23 AC016757.3
 Protein LOC151174
 21
 0.75
chr1_148854904_148855383 0.23 ENSG00000222854
 .
 58239
 0.13
chr2_25143411_25143810 0.23 ADCY3
 adenylate cyclase 3
 902
 0.57
chr11_118016566_118017132 0.23 SCN4B
 sodium channel, voltage-gated, type IV, beta subunit
 6686
 0.16
chr20_821989_822287 0.23 FAM110A
 family with sequence similarity 110, member A
 3147
 0.3
chr5_76925321_76925875 0.23 WDR41
 WD repeat domain 41
 9162
 0.23
chr3_13045853_13046441 0.22 IQSEC1
 IQ motif and Sec7 domain 1
 17611
 0.25
chr11_118767424_118768222 0.22 RP11-158I9.5
9372
 0.09
chr1_9790555_9790706 0.22 PIK3CD
 phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta
 12503
 0.17
chr17_77788487_77789261 0.22 ENSG00000238331
 .
 4396
 0.16
chr2_10417901_10418493 0.22 ENSG00000264030
 .
 2560
 0.25
chr2_241375193_241375732 0.22 GPC1
 glypican 1
 374
 0.85
chr2_179059335_179059702 0.22 OSBPL6
 oxysterol binding protein-like 6
 142
 0.97
chr16_4366412_4367009 0.22 GLIS2
 GLIS family zinc finger 2
 1948
 0.24
chr12_1640143_1640389 0.21 WNT5B
 wingless-type MMTV integration site family, member 5B
 281
 0.93
chr1_147072101_147072252 0.21 ACP6
 acid phosphatase 6, lysophosphatidic
 58940
 0.12
chr2_148602775_148603076 0.21 ACVR2A
 activin A receptor, type IIA
 740
 0.7
chr17_42198349_42198622 0.21 HDAC5
 histone deacetylase 5
 2158
 0.16
chrX_57021806_57021957 0.21 SPIN3
 spindlin family, member 3
 88
 0.98
chr15_65067250_65067549 0.21 RBPMS2
 RNA binding protein with multiple splicing 2
 387
 0.8
chr10_134755869_134756456 0.21 TTC40
 tetratricopeptide repeat domain 40
 73
 0.98
chr18_10454407_10454669 0.21 APCDD1
 adenomatosis polyposis coli down-regulated 1
 87
 0.98
chr8_95653134_95653505 0.21 ESRP1
 epithelial splicing regulatory protein 1
 17
 0.97
chr17_1388316_1388880 0.21 MYO1C
 myosin IC
 63
 0.96
chr15_56035205_56035434 0.21 PRTG
 protogenin
 31
 0.98
chr16_54319563_54320025 0.20 IRX3
 iroquois homeobox 3
 27
 0.98
chr13_114898126_114898522 0.20 RASA3
 RAS p21 protein activator 3
 238
 0.94
chr3_133614378_133614535 0.20 RAB6B
 RAB6B, member RAS oncogene family
 17
 0.98
chr2_112896432_112896734 0.20 FBLN7
 fibulin 7
 423
 0.88
chr19_3950919_3951410 0.20 DAPK3
 death-associated protein kinase 3
 9993
 0.1
chr7_64786949_64787100 0.20 ENSG00000252102
 .
 4608
 0.21
chr16_89149708_89149925 0.20 ACSF3
 acyl-CoA synthetase family member 3
 4967
 0.19
chr16_28073787_28074211 0.20 GSG1L
 GSG1-like
 823
 0.66
chr10_135043950_135044439 0.20 UTF1
 undifferentiated embryonic cell transcription factor 1
 416
 0.76
chr8_23260829_23261542 0.20 LOXL2
 lysyl oxidase-like 2
 404
 0.85
chr6_43243469_43244256 0.20 SLC22A7
 solute carrier family 22 (organic anion transporter), member 7
 21874
 0.11
chr8_144976584_144976776 0.20 EPPK1
 epiplakin 1
 24048
 0.09
chr16_14396181_14396446 0.19 ENSG00000207639
 .
 1511
 0.39
chr19_7723026_7723421 0.19 RETN
 resistin
 10707
 0.07
chr19_49250260_49250724 0.19 IZUMO1
 izumo sperm-egg fusion 1
 326
 0.76
chr8_144513420_144513883 0.19 MAFA
 v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog A
 1075
 0.37
chr16_70719204_70719725 0.19 MTSS1L
 metastasis suppressor 1-like
 505
 0.73
chr16_23877021_23877290 0.19 PRKCB
 protein kinase C, beta
 28611
 0.21
chr4_7049798_7050097 0.19 RP11-367J11.2
1989
 0.21
chr4_186131098_186131398 0.19 SNX25
 sorting nexin 25
 15
 0.92
chr7_6661507_6661658 0.19 ZNF853
 zinc finger protein 853
 6334
 0.13
chr6_150921076_150921438 0.19 PLEKHG1
 pleckstrin homology domain containing, family G (with RhoGef domain) member 1
 238
 0.82
chr11_46326677_46326971 0.19 CREB3L1
 cAMP responsive element binding protein 3-like 1
 5884
 0.18
chr19_7734010_7734283 0.19 RETN
 resistin
 67
 0.93
chr11_279490_280193 0.18 NLRP6
 NLR family, pyrin domain containing 6
 1271
 0.22
chr22_39323300_39323451 0.18 APOBEC3A
 apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3A
 25381
 0.12
chr2_121100177_121100328 0.18 INHBB
 inhibin, beta B
 3467
 0.32
chr17_36508561_36508839 0.18 SOCS7
 suppressor of cytokine signaling 7
 126
 0.95
chr19_42828405_42828656 0.18 MEGF8
 multiple EGF-like-domains 8
 1231
 0.29
chr10_83633826_83633977 0.18 NRG3
 neuregulin 3
 1169
 0.66
chr19_42419984_42420278 0.18 CTD-2575K13.6
5882
 0.13
chr12_113623598_113623967 0.18 RITA1
 RBPJ interacting and tubulin associated 1
 435
 0.46
chr8_101803753_101803904 0.18 ENSG00000202001
 .
 36405
 0.12
chr8_136683849_136684000 0.18 ENSG00000199652
 .
 70814
 0.13
chr7_2672947_2673687 0.18 TTYH3
 tweety family member 3
 1527
 0.39
chr19_1651787_1652144 0.18 TCF3
 transcription factor 3
 361
 0.81
chr11_70049554_70049852 0.18 FADD
 Fas (TNFRSF6)-associated via death domain
 434
 0.77
chr15_100881699_100882205 0.18 ADAMTS17
 ADAM metallopeptidase with thrombospondin type 1 motif, 17
 258
 0.94
chr19_13050056_13050207 0.18 CALR
 calreticulin
 672
 0.39
chr1_53528255_53528820 0.18 PODN
 podocan
 652
 0.65
chr15_65204064_65204408 0.18 ANKDD1A
 ankyrin repeat and death domain containing 1A
 116
 0.96
chr18_53954362_53954513 0.18 ENSG00000201816
 .
 207612
 0.03
chr21_34863671_34863822 0.18 DNAJC28
 DnaJ (Hsp40) homolog, subfamily C, member 28
 34
 0.96
chr3_69246534_69246770 0.18 FRMD4B
 FERM domain containing 4B
 1769
 0.44
chr3_159481915_159482604 0.18 IQCJ-SCHIP1
 IQCJ-SCHIP1 readthrough
 254
 0.92
chr19_30334052_30334510 0.18 CCNE1
 cyclin E1
 26171
 0.23
chr2_176995253_176995433 0.18 HOXD8
 homeobox D8
 258
 0.79
chr2_109827837_109827988 0.18 ENSG00000264934
 .
 69868
 0.11
chr1_63788558_63788978 0.18 FOXD3
 forkhead box D3
 38
 0.89
chr10_21785246_21785539 0.18 ENSG00000222071
 .
 178
 0.86
chr16_31094623_31094782 0.18 PRSS53
 protease, serine, 53
 5582
 0.07
chr8_145115066_145115529 0.17 OPLAH
 5-oxoprolinase (ATP-hydrolysing)
 287
 0.77
chr2_287605_287899 0.17 FAM150B
 family with sequence similarity 150, member B
 65
 0.95
chr5_14144859_14145160 0.17 TRIO
 trio Rho guanine nucleotide exchange factor
 1180
 0.66
chr7_104987897_104988048 0.17 ENSG00000201179
 .
 14735
 0.21
chr8_61689037_61689188 0.17 RP11-33I11.2
33053
 0.2
chr1_17922092_17922243 0.17 ARHGEF10L
 Rho guanine nucleotide exchange factor (GEF) 10-like
 7256
 0.28
chr10_73514684_73515259 0.17 C10orf54
 chromosome 10 open reading frame 54
 2416
 0.29
chr17_20435355_20435506 0.17 AC015818.3
8370
 0.16
chr5_141017161_141017642 0.17 RELL2
 RELT-like 2
 392
 0.67
chr2_240170929_240171080 0.17 ENSG00000265215
 .
 56153
 0.1
chr10_72647360_72647920 0.17 PCBD1
 pterin-4 alpha-carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha
 901
 0.61
chr19_53971416_53971567 0.17 ZNF813
 zinc finger protein 813
 491
 0.73
chr8_144479919_144480248 0.17 RP11-909N17.2
14836
 0.09
chr20_3062971_3063207 0.17 AVP
 arginine vasopressin
 2281
 0.19
chr1_955590_955924 0.17 AGRN
 agrin
 254
 0.82
chr19_1408158_1408394 0.17 DAZAP1
 DAZ associated protein 1
 542
 0.53
chr11_1593630_1593781 0.17 KRTAP5-AS1
 KRTAP5-1/KRTAP5-2 antisense RNA 1
 266
 0.69
chr19_1757452_1757848 0.17 ONECUT3
 one cut homeobox 3
 5278
 0.14
chr19_34286590_34286927 0.17 KCTD15
 potassium channel tetramerization domain containing 15
 80
 0.98
chr15_101676818_101676969 0.17 RP11-505E24.2
50622
 0.14
chr2_174127618_174127769 0.17 MLK7-AS1
 MLK7 antisense RNA 1
 8655
 0.3
chr10_134441856_134442007 0.17 INPP5A
 inositol polyphosphate-5-phosphatase, 40kDa
 20501
 0.24
chr7_156400190_156400570 0.17 ENSG00000182648
 .
 1922
 0.35
chr5_72742553_72742920 0.17 FOXD1
 forkhead box D1
 1616
 0.4
chr2_36583944_36584246 0.17 CRIM1
 cysteine rich transmembrane BMP regulator 1 (chordin-like)
 481
 0.89
chr22_50616510_50616763 0.17 PANX2
 pannexin 2
 7476
 0.09
chrX_153824799_153824991 0.17 CTAG1A
 cancer/testis antigen 1A
 11477
 0.11
chr9_129232305_129232865 0.17 ENSG00000252985
 .
 43413
 0.14
chr19_41329835_41330195 0.17 EGLN2
 egl-9 family hypoxia-inducible factor 2
 16867
 0.11
chr17_58216738_58217239 0.17 CA4
 carbonic anhydrase IV
 10309
 0.17
chr5_139026736_139026950 0.17 CXXC5
 CXXC finger protein 5
 41
 0.98
chr16_88759405_88759694 0.17 RP5-1142A6.5
3360
 0.09
chr8_126518150_126518406 0.17 ENSG00000266452
 .
 61471
 0.13
chr9_130601372_130601801 0.16 ENSG00000222455
 .
 1915
 0.15
chr11_3164459_3164610 0.16 OSBPL5
 oxysterol binding protein-like 5
 13975
 0.15
chr22_42679390_42679541 0.16 TCF20
 transcription factor 20 (AR1)
 60157
 0.11
chr11_64059326_64060001 0.16 KCNK4
 potassium channel, subfamily K, member 4
 181
 0.83
chr21_15588417_15588693 0.16 RBM11
 RNA binding motif protein 11
 56
 0.98
chr3_85009901_85010052 0.16 CADM2
 cell adhesion molecule 2
 1279
 0.6
chr19_497502_497658 0.16 MADCAM1
 mucosal vascular addressin cell adhesion molecule 1
 1080
 0.32
chrX_139846898_139847148 0.16 CDR1
 cerebellar degeneration-related protein 1, 34kDa
 19700
 0.22
chr2_27303559_27303835 0.16 EMILIN1
 elastin microfibril interfacer 1
 2262
 0.12
chr10_104436480_104437015 0.16 TRIM8
 tripartite motif containing 8
 32103
 0.12
chr17_76408680_76409216 0.16 PGS1
 phosphatidylglycerophosphate synthase 1
 8903
 0.14
chr19_1154320_1154471 0.16 SBNO2
 strawberry notch homolog 2 (Drosophila)
 740
 0.54
chr19_3428790_3429002 0.16 C19orf77
 chromosome 19 open reading frame 77
 49590
 0.08
chr16_23859758_23859996 0.16 PRKCB
 protein kinase C, beta
 11333
 0.24
chr19_51842265_51842416 0.16 CTD-2616J11.16
1609
 0.17
chr8_98656994_98657282 0.16 MTDH
 metadherin
 117
 0.98
chr7_149156298_149156814 0.16 ZNF777
 zinc finger protein 777
 1658
 0.41
chr3_128568896_128569192 0.16 RP11-723O4.2
15403
 0.17
chr6_43739183_43739466 0.16 VEGFA
 vascular endothelial growth factor A
 340
 0.78
chr1_205012234_205012598 0.16 CNTN2
 contactin 2 (axonal)
 91
 0.97
chr2_10425893_10426393 0.16 ENSG00000264030
 .
 5386
 0.18

Histogram of CRE-TSS distances for CREs targeted by :

Histogram of

Rank distribution of CRE target scores:

Histogram of target CRE score.

Distribution of target CREs across different genomic regions:

Weighted Piechart of Weighted Piechart of Weighted Piechart of

Network of associatons between targets according to the STRING database.

First level regulatory network of SIN3A_CHD1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.5 GO:0045163 clustering of voltage-gated potassium channels(GO:0045163)
0.1 0.6 GO:0032808 lacrimal gland development(GO:0032808)
0.1 0.5 GO:0060754 mast cell chemotaxis(GO:0002551) regulation of mast cell chemotaxis(GO:0060753) positive regulation of mast cell chemotaxis(GO:0060754) mast cell migration(GO:0097531)
0.1 0.3 GO:0032927 positive regulation of activin receptor signaling pathway(GO:0032927)
0.1 0.3 GO:0060242 contact inhibition(GO:0060242)
0.1 0.4 GO:0060028 convergent extension involved in axis elongation(GO:0060028)
0.1 0.2 GO:0033622 integrin activation(GO:0033622)
0.1 0.4 GO:0022011 myelination in peripheral nervous system(GO:0022011) peripheral nervous system axon ensheathment(GO:0032292)
0.1 0.2 GO:0030644 cellular chloride ion homeostasis(GO:0030644) chloride ion homeostasis(GO:0055064)
0.1 0.2 GO:0021780 spinal cord oligodendrocyte cell differentiation(GO:0021529) spinal cord oligodendrocyte cell fate specification(GO:0021530) oligodendrocyte cell fate specification(GO:0021778) glial cell fate specification(GO:0021780)
0.1 0.1 GO:0035405 histone-threonine phosphorylation(GO:0035405)
0.1 0.2 GO:0060235 lens induction in camera-type eye(GO:0060235)
0.0 0.2 GO:0048935 peripheral nervous system neuron development(GO:0048935)
0.0 0.1 GO:0002025 vasodilation by norepinephrine-epinephrine involved in regulation of systemic arterial blood pressure(GO:0002025)
0.0 0.1 GO:0044321 cellular response to leptin stimulus(GO:0044320) response to leptin(GO:0044321)
0.0 0.1 GO:0015825 L-serine transport(GO:0015825)
0.0 0.1 GO:0010842 retina layer formation(GO:0010842)
0.0 0.1 GO:0018125 peptidyl-cysteine methylation(GO:0018125)
0.0 0.1 GO:0060394 negative regulation of pathway-restricted SMAD protein phosphorylation(GO:0060394)
0.0 0.0 GO:2000300 regulation of synaptic vesicle transport(GO:1902803) regulation of synaptic vesicle exocytosis(GO:2000300)
0.0 0.1 GO:0032730 regulation of interleukin-1 alpha production(GO:0032650) positive regulation of interleukin-1 alpha production(GO:0032730)
0.0 0.1 GO:0045110 intermediate filament bundle assembly(GO:0045110)
0.0 0.0 GO:0002032 desensitization of G-protein coupled receptor protein signaling pathway by arrestin(GO:0002032)
0.0 0.2 GO:0016102 retinoic acid biosynthetic process(GO:0002138) diterpenoid biosynthetic process(GO:0016102)
0.0 0.1 GO:0061072 iris morphogenesis(GO:0061072)
0.0 0.3 GO:0010560 positive regulation of glycoprotein biosynthetic process(GO:0010560) positive regulation of glycoprotein metabolic process(GO:1903020)
0.0 0.2 GO:0055026 negative regulation of cardiac muscle tissue growth(GO:0055022) negative regulation of cardiac muscle tissue development(GO:0055026) negative regulation of cardiac muscle cell proliferation(GO:0060044) negative regulation of heart growth(GO:0061117)
0.0 0.2 GO:0090049 regulation of cell migration involved in sprouting angiogenesis(GO:0090049) regulation of sprouting angiogenesis(GO:1903670)
0.0 0.2 GO:0010508 positive regulation of autophagy(GO:0010508)
0.0 0.2 GO:0045662 negative regulation of myoblast differentiation(GO:0045662)
0.0 0.2 GO:0019987 obsolete negative regulation of anti-apoptosis(GO:0019987)
0.0 0.1 GO:0072217 negative regulation of metanephros development(GO:0072217)
0.0 0.1 GO:0001574 ganglioside biosynthetic process(GO:0001574)
0.0 0.1 GO:0032926 negative regulation of activin receptor signaling pathway(GO:0032926)
0.0 0.2 GO:0031061 negative regulation of histone methylation(GO:0031061)
0.0 0.1 GO:0006435 threonyl-tRNA aminoacylation(GO:0006435)
0.0 0.1 GO:0001711 endodermal cell fate commitment(GO:0001711) endodermal cell fate specification(GO:0001714) endodermal cell differentiation(GO:0035987) regulation of endodermal cell fate specification(GO:0042663) regulation of endodermal cell differentiation(GO:1903224)
0.0 0.4 GO:0031581 hemidesmosome assembly(GO:0031581)
0.0 0.3 GO:0033144 negative regulation of intracellular steroid hormone receptor signaling pathway(GO:0033144)
0.0 0.1 GO:0051124 synaptic growth at neuromuscular junction(GO:0051124)
0.0 0.1 GO:0019276 UDP-N-acetylgalactosamine metabolic process(GO:0019276)
0.0 0.1 GO:0016241 regulation of macroautophagy(GO:0016241) negative regulation of macroautophagy(GO:0016242)
0.0 0.2 GO:0002313 mature B cell differentiation involved in immune response(GO:0002313)
0.0 0.1 GO:0006556 S-adenosylmethionine biosynthetic process(GO:0006556)
0.0 0.1 GO:0070932 histone H3 deacetylation(GO:0070932) histone H4 deacetylation(GO:0070933)
0.0 0.2 GO:0032717 negative regulation of interleukin-8 production(GO:0032717)
0.0 0.2 GO:0050930 induction of positive chemotaxis(GO:0050930)
0.0 0.1 GO:0034723 DNA replication-dependent nucleosome organization(GO:0034723)
0.0 0.1 GO:0033152 immunoglobulin V(D)J recombination(GO:0033152)
0.0 0.1 GO:0060023 soft palate development(GO:0060023)
0.0 0.1 GO:0071731 response to nitric oxide(GO:0071731)
0.0 0.1 GO:0021913 regulation of transcription from RNA polymerase II promoter involved in ventral spinal cord interneuron specification(GO:0021913)
0.0 0.2 GO:0048895 sensory system development(GO:0048880) lateral line nerve development(GO:0048892) lateral line nerve glial cell differentiation(GO:0048895) lateral line system development(GO:0048925) lateral line nerve glial cell development(GO:0048937) iridophore differentiation(GO:0050935)
0.0 0.2 GO:0030853 negative regulation of granulocyte differentiation(GO:0030853)
0.0 0.1 GO:0051001 negative regulation of nitric-oxide synthase activity(GO:0051001)
0.0 0.1 GO:0032227 negative regulation of synaptic transmission, dopaminergic(GO:0032227)
0.0 0.1 GO:2000095 regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000095)
0.0 0.1 GO:0010614 negative regulation of cardiac muscle hypertrophy(GO:0010614)
0.0 0.0 GO:0043380 T-helper cell lineage commitment(GO:0002295) CD4-positive, alpha-beta T cell lineage commitment(GO:0043373) memory T cell differentiation(GO:0043379) regulation of memory T cell differentiation(GO:0043380) positive regulation of memory T cell differentiation(GO:0043382) T-helper 17 type immune response(GO:0072538) T-helper 17 cell differentiation(GO:0072539) T-helper 17 cell lineage commitment(GO:0072540) regulation of T-helper 17 type immune response(GO:2000316) positive regulation of T-helper 17 type immune response(GO:2000318) regulation of T-helper 17 cell differentiation(GO:2000319) positive regulation of T-helper 17 cell differentiation(GO:2000321) regulation of T-helper 17 cell lineage commitment(GO:2000328) positive regulation of T-helper 17 cell lineage commitment(GO:2000330)
0.0 0.1 GO:0031558 obsolete induction of apoptosis in response to chemical stimulus(GO:0031558)
0.0 0.1 GO:0003056 regulation of vascular smooth muscle contraction(GO:0003056)
0.0 0.1 GO:0035054 embryonic heart tube anterior/posterior pattern specification(GO:0035054)
0.0 0.1 GO:0003077 obsolete negative regulation of diuresis(GO:0003077)
0.0 0.2 GO:0007172 signal complex assembly(GO:0007172)
0.0 0.1 GO:0008615 pyridoxine metabolic process(GO:0008614) pyridoxine biosynthetic process(GO:0008615) vitamin B6 metabolic process(GO:0042816) vitamin B6 biosynthetic process(GO:0042819)
0.0 0.0 GO:0070141 response to UV-A(GO:0070141)
0.0 0.0 GO:0002328 pro-B cell differentiation(GO:0002328)
0.0 0.2 GO:0070265 necrotic cell death(GO:0070265)
0.0 0.0 GO:0060648 mammary gland bud morphogenesis(GO:0060648)
0.0 0.1 GO:0000089 mitotic metaphase(GO:0000089)
0.0 0.1 GO:0010592 positive regulation of lamellipodium assembly(GO:0010592) positive regulation of lamellipodium organization(GO:1902745)
0.0 0.1 GO:0045924 regulation of female receptivity(GO:0045924) female mating behavior(GO:0060180)
0.0 0.1 GO:0016188 synaptic vesicle maturation(GO:0016188)
0.0 0.4 GO:0032012 regulation of ARF protein signal transduction(GO:0032012)
0.0 0.0 GO:0022009 establishment of endothelial blood-brain barrier(GO:0014045) central nervous system vasculogenesis(GO:0022009)
0.0 0.1 GO:0090136 epithelial cell-cell adhesion(GO:0090136)
0.0 0.1 GO:0045343 MHC class I biosynthetic process(GO:0045341) regulation of MHC class I biosynthetic process(GO:0045343)
0.0 0.1 GO:0046827 positive regulation of protein export from nucleus(GO:0046827)
0.0 0.0 GO:0048934 peripheral nervous system neuron differentiation(GO:0048934)
0.0 0.1 GO:0040015 negative regulation of multicellular organism growth(GO:0040015)
0.0 0.1 GO:0055098 response to low-density lipoprotein particle(GO:0055098)
0.0 0.1 GO:0007000 nucleolus organization(GO:0007000)
0.0 0.2 GO:0000085 mitotic G2 phase(GO:0000085) G2 phase(GO:0051319)
0.0 0.0 GO:0051154 negative regulation of striated muscle cell differentiation(GO:0051154)
0.0 0.1 GO:0048702 embryonic neurocranium morphogenesis(GO:0048702)
0.0 0.0 GO:0030538 embryonic genitalia morphogenesis(GO:0030538)
0.0 0.1 GO:0009804 phenylpropanoid metabolic process(GO:0009698) coumarin metabolic process(GO:0009804)
0.0 0.1 GO:0016322 neuron remodeling(GO:0016322)
0.0 0.3 GO:0034199 activation of protein kinase A activity(GO:0034199)
0.0 0.1 GO:0051873 disruption by host of symbiont cells(GO:0051852) killing by host of symbiont cells(GO:0051873)
0.0 0.1 GO:0033197 response to vitamin E(GO:0033197)
0.0 0.1 GO:0032898 neurotrophin production(GO:0032898)
0.0 0.1 GO:0006729 tetrahydrobiopterin biosynthetic process(GO:0006729)
0.0 0.1 GO:0045767 obsolete regulation of anti-apoptosis(GO:0045767)
0.0 0.2 GO:0032733 positive regulation of interleukin-10 production(GO:0032733)
0.0 0.1 GO:0002282 microglial cell activation involved in immune response(GO:0002282)
0.0 0.0 GO:0003402 planar cell polarity pathway involved in axis elongation(GO:0003402)
0.0 0.0 GO:0007500 mesodermal cell fate determination(GO:0007500)
0.0 0.1 GO:0017000 antibiotic metabolic process(GO:0016999) antibiotic biosynthetic process(GO:0017000)
0.0 0.1 GO:0010447 response to acidic pH(GO:0010447)
0.0 0.1 GO:0046655 folic acid metabolic process(GO:0046655)
0.0 0.1 GO:0010586 miRNA metabolic process(GO:0010586) miRNA catabolic process(GO:0010587)
0.0 0.0 GO:0051971 positive regulation of transmission of nerve impulse(GO:0051971)
0.0 0.1 GO:0045071 negative regulation of viral genome replication(GO:0045071)
0.0 0.2 GO:0007076 mitotic chromosome condensation(GO:0007076)
0.0 0.2 GO:0032332 positive regulation of chondrocyte differentiation(GO:0032332)
0.0 0.0 GO:0001921 positive regulation of receptor recycling(GO:0001921)
0.0 0.1 GO:0030033 microvillus assembly(GO:0030033) microvillus organization(GO:0032528)
0.0 0.4 GO:0006904 vesicle docking involved in exocytosis(GO:0006904)
0.0 0.0 GO:0034983 peptidyl-lysine deacetylation(GO:0034983)
0.0 0.1 GO:0006020 inositol metabolic process(GO:0006020)
0.0 0.1 GO:0040019 positive regulation of embryonic development(GO:0040019)
0.0 0.1 GO:0032968 positive regulation of transcription elongation from RNA polymerase II promoter(GO:0032968)
0.0 0.1 GO:0016093 polyprenol metabolic process(GO:0016093) dolichol metabolic process(GO:0019348)
0.0 0.1 GO:0060836 lymphatic endothelial cell differentiation(GO:0060836)
0.0 0.1 GO:0045085 negative regulation of interleukin-2 biosynthetic process(GO:0045085)
0.0 0.0 GO:0006295 nucleotide-excision repair, DNA incision, 3'-to lesion(GO:0006295)
0.0 0.1 GO:0006538 glutamate catabolic process(GO:0006538)
0.0 0.1 GO:0006685 sphingomyelin catabolic process(GO:0006685)
0.0 0.1 GO:0051973 positive regulation of telomerase activity(GO:0051973)
0.0 0.0 GO:2000757 negative regulation of histone acetylation(GO:0035067) negative regulation of protein acetylation(GO:1901984) negative regulation of peptidyl-lysine acetylation(GO:2000757)
0.0 0.0 GO:0031659 regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition of mitotic cell cycle(GO:0031657) positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition of mitotic cell cycle(GO:0031659)
0.0 0.1 GO:0042117 monocyte activation(GO:0042117)
0.0 0.0 GO:0030091 protein repair(GO:0030091)
0.0 0.1 GO:0090231 regulation of spindle checkpoint(GO:0090231)
0.0 0.1 GO:0050435 beta-amyloid metabolic process(GO:0050435)
0.0 0.1 GO:0045625 regulation of T-helper 1 cell differentiation(GO:0045625)
0.0 0.0 GO:0018076 N-terminal peptidyl-lysine acetylation(GO:0018076)
0.0 0.0 GO:0051709 regulation of killing of cells of other organism(GO:0051709) positive regulation of killing of cells of other organism(GO:0051712)
0.0 0.0 GO:0045079 negative regulation of chemokine production(GO:0032682) negative regulation of chemokine biosynthetic process(GO:0045079)
0.0 0.1 GO:0015919 peroxisomal membrane transport(GO:0015919)
0.0 0.1 GO:0055015 ventricular cardiac muscle cell development(GO:0055015)
0.0 0.0 GO:0034135 regulation of toll-like receptor 2 signaling pathway(GO:0034135)
0.0 0.2 GO:0007342 fusion of sperm to egg plasma membrane(GO:0007342)
0.0 0.0 GO:0042219 cellular modified amino acid catabolic process(GO:0042219)
0.0 0.1 GO:0003310 pancreatic A cell differentiation(GO:0003310)
0.0 0.0 GO:0002281 macrophage activation involved in immune response(GO:0002281)
0.0 0.1 GO:0090023 positive regulation of neutrophil chemotaxis(GO:0090023) positive regulation of neutrophil migration(GO:1902624)
0.0 0.0 GO:0010882 regulation of cardiac muscle contraction by calcium ion signaling(GO:0010882)
0.0 0.1 GO:0050957 equilibrioception(GO:0050957)
0.0 0.0 GO:0014051 gamma-aminobutyric acid secretion(GO:0014051) regulation of gamma-aminobutyric acid secretion(GO:0014052)
0.0 0.1 GO:0009109 coenzyme catabolic process(GO:0009109)
0.0 0.0 GO:0010457 centriole-centriole cohesion(GO:0010457)
0.0 0.0 GO:0009180 ADP biosynthetic process(GO:0006172) purine nucleoside diphosphate biosynthetic process(GO:0009136) purine ribonucleoside diphosphate biosynthetic process(GO:0009180) ribonucleoside diphosphate biosynthetic process(GO:0009188)
0.0 0.1 GO:0051972 regulation of telomerase activity(GO:0051972)
0.0 0.0 GO:0030187 melatonin metabolic process(GO:0030186) melatonin biosynthetic process(GO:0030187)
0.0 0.1 GO:0002089 lens morphogenesis in camera-type eye(GO:0002089)
0.0 0.0 GO:0006384 transcription initiation from RNA polymerase III promoter(GO:0006384)
0.0 0.1 GO:0042119 neutrophil activation(GO:0042119)
0.0 0.1 GO:0060527 prostate glandular acinus morphogenesis(GO:0060526) prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis(GO:0060527)
0.0 0.0 GO:0043276 anoikis(GO:0043276)
0.0 0.0 GO:0000733 DNA strand renaturation(GO:0000733)
0.0 0.0 GO:0010459 negative regulation of heart rate(GO:0010459)
0.0 0.0 GO:0048478 replication fork protection(GO:0048478)
0.0 0.1 GO:0002478 antigen processing and presentation of exogenous peptide antigen(GO:0002478)
0.0 0.1 GO:0060456 positive regulation of digestive system process(GO:0060456)
0.0 0.1 GO:0060391 positive regulation of SMAD protein import into nucleus(GO:0060391)
0.0 0.1 GO:0015871 choline transport(GO:0015871)
0.0 0.0 GO:0071436 sodium ion export(GO:0071436)
0.0 0.1 GO:0007549 dosage compensation(GO:0007549)
0.0 0.0 GO:0009189 deoxyribonucleoside diphosphate biosynthetic process(GO:0009189)
0.0 0.0 GO:0043983 histone H4-K12 acetylation(GO:0043983)
0.0 0.0 GO:0046931 pore complex assembly(GO:0046931)
0.0 0.1 GO:0016558 protein import into peroxisome matrix(GO:0016558)
0.0 0.0 GO:0010815 bradykinin catabolic process(GO:0010815)
0.0 0.0 GO:0032237 activation of store-operated calcium channel activity(GO:0032237) regulation of store-operated calcium channel activity(GO:1901339) positive regulation of store-operated calcium channel activity(GO:1901341)
0.0 0.1 GO:0040023 establishment of nucleus localization(GO:0040023)
0.0 0.1 GO:0006689 ganglioside catabolic process(GO:0006689)
0.0 0.1 GO:0007185 transmembrane receptor protein tyrosine phosphatase signaling pathway(GO:0007185)
0.0 0.0 GO:0045603 positive regulation of endothelial cell differentiation(GO:0045603)
0.0 0.0 GO:0002513 tolerance induction to self antigen(GO:0002513)
0.0 0.0 GO:0002361 CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation(GO:0002361)
0.0 0.1 GO:0006978 DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:0006978)
0.0 0.0 GO:0032011 ARF protein signal transduction(GO:0032011)
0.0 0.0 GO:0051386 regulation of neurotrophin TRK receptor signaling pathway(GO:0051386)
0.0 0.0 GO:0006208 pyrimidine nucleobase catabolic process(GO:0006208) thymine catabolic process(GO:0006210) thymine metabolic process(GO:0019859)
0.0 0.0 GO:0009756 carbohydrate mediated signaling(GO:0009756)
0.0 0.0 GO:0006772 thiamine metabolic process(GO:0006772)
0.0 0.1 GO:0048630 skeletal muscle tissue growth(GO:0048630)
0.0 0.1 GO:0015671 oxygen transport(GO:0015671)
0.0 0.0 GO:0006498 N-terminal protein lipidation(GO:0006498)
0.0 0.0 GO:0001911 negative regulation of leukocyte mediated cytotoxicity(GO:0001911)
0.0 0.1 GO:0015911 plasma membrane long-chain fatty acid transport(GO:0015911)
0.0 0.0 GO:0046968 peptide antigen transport(GO:0046968)
0.0 0.3 GO:0003333 amino acid transmembrane transport(GO:0003333)
0.0 0.1 GO:0043954 cell junction maintenance(GO:0034331) cellular component maintenance(GO:0043954) cell-cell junction maintenance(GO:0045217)
0.0 0.1 GO:0030511 positive regulation of transforming growth factor beta receptor signaling pathway(GO:0030511) positive regulation of cellular response to transforming growth factor beta stimulus(GO:1903846)
0.0 0.1 GO:0070570 regulation of axon regeneration(GO:0048679) regulation of neuron projection regeneration(GO:0070570)
0.0 0.1 GO:0055078 sodium ion homeostasis(GO:0055078)
0.0 0.0 GO:0070172 positive regulation of tooth mineralization(GO:0070172)
0.0 0.0 GO:0001845 phagolysosome assembly(GO:0001845) phagosome maturation(GO:0090382)
0.0 0.0 GO:0009301 snRNA transcription(GO:0009301)
0.0 0.0 GO:0032613 interleukin-10 production(GO:0032613)
0.0 0.0 GO:0045006 DNA deamination(GO:0045006)
0.0 0.1 GO:0050832 defense response to fungus(GO:0050832)
0.0 0.0 GO:0050689 negative regulation of defense response to virus by host(GO:0050689)
0.0 0.0 GO:0032971 regulation of muscle filament sliding(GO:0032971) regulation of actin filament-based movement(GO:1903115)
0.0 0.0 GO:0061318 renal filtration cell differentiation(GO:0061318) glomerular epithelium development(GO:0072010) glomerular visceral epithelial cell differentiation(GO:0072112) glomerular epithelial cell differentiation(GO:0072311)
0.0 0.0 GO:0060008 Sertoli cell differentiation(GO:0060008) Sertoli cell development(GO:0060009)
0.0 0.0 GO:0006591 ornithine metabolic process(GO:0006591)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.1 0.2 GO:0070852 cell body fiber(GO:0070852)
0.1 0.2 GO:0034673 inhibin-betaglycan-ActRII complex(GO:0034673)
0.1 0.3 GO:0033268 node of Ranvier(GO:0033268)
0.0 0.2 GO:0005638 lamin filament(GO:0005638)
0.0 0.3 GO:0016461 unconventional myosin complex(GO:0016461)
0.0 0.2 GO:0001939 female pronucleus(GO:0001939)
0.0 0.3 GO:0032839 dendrite cytoplasm(GO:0032839)
0.0 0.6 GO:0005720 nuclear heterochromatin(GO:0005720)
0.0 0.1 GO:0071986 Ragulator complex(GO:0071986)
0.0 0.1 GO:0000800 lateral element(GO:0000800)
0.0 0.1 GO:0005594 collagen type IX trimer(GO:0005594)
0.0 0.1 GO:0000137 Golgi cis cisterna(GO:0000137)
0.0 0.1 GO:0070776 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.0 0.1 GO:0048179 activin receptor complex(GO:0048179)
0.0 0.3 GO:0001772 immunological synapse(GO:0001772)
0.0 0.1 GO:0032009 early phagosome(GO:0032009)
0.0 0.1 GO:0071664 catenin-TCF7L2 complex(GO:0071664)
0.0 0.1 GO:0016533 cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533)
0.0 0.1 GO:0046581 intercellular canaliculus(GO:0046581)
0.0 0.1 GO:0000300 obsolete peripheral to membrane of membrane fraction(GO:0000300)
0.0 0.1 GO:0031254 uropod(GO:0001931) cell trailing edge(GO:0031254)
0.0 0.1 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
0.0 0.1 GO:0070022 transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.0 0.1 GO:0042824 MHC class I peptide loading complex(GO:0042824)
0.0 0.1 GO:0030056 hemidesmosome(GO:0030056)
0.0 0.3 GO:0030867 rough endoplasmic reticulum membrane(GO:0030867)
0.0 0.1 GO:0005678 obsolete chromatin assembly complex(GO:0005678)
0.0 0.1 GO:0030893 meiotic cohesin complex(GO:0030893)
0.0 0.2 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.0 0.1 GO:0005845 mRNA cap binding complex(GO:0005845) RNA cap binding complex(GO:0034518)
0.0 0.0 GO:0044462 external encapsulating structure part(GO:0044462)
0.0 0.2 GO:0031258 lamellipodium membrane(GO:0031258)
0.0 0.2 GO:0031519 PcG protein complex(GO:0031519)
0.0 0.1 GO:0016589 NURF complex(GO:0016589)
0.0 0.2 GO:0031105 septin complex(GO:0031105) septin cytoskeleton(GO:0032156)
0.0 0.1 GO:0030673 axolemma(GO:0030673)
0.0 0.0 GO:0030895 apolipoprotein B mRNA editing enzyme complex(GO:0030895)
0.0 0.0 GO:0000124 SAGA complex(GO:0000124)
0.0 0.1 GO:0001740 Barr body(GO:0001740)
0.0 0.0 GO:1990316 ATG1/ULK1 kinase complex(GO:1990316)
0.0 0.1 GO:0008278 cohesin complex(GO:0008278)
0.0 0.4 GO:0005884 actin filament(GO:0005884)
0.0 0.1 GO:0033179 proton-transporting V-type ATPase, V0 domain(GO:0033179)
0.0 0.1 GO:0035189 Rb-E2F complex(GO:0035189)
0.0 0.0 GO:0070820 tertiary granule(GO:0070820)
0.0 0.1 GO:0001527 microfibril(GO:0001527)
0.0 0.0 GO:0045323 interleukin-1 receptor complex(GO:0045323)
0.0 0.1 GO:0042382 paraspeckles(GO:0042382)
0.0 0.0 GO:0031527 filopodium membrane(GO:0031527)
0.0 0.2 GO:0043198 dendritic shaft(GO:0043198)
0.0 0.0 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)
0.0 0.1 GO:0031264 death-inducing signaling complex(GO:0031264)
0.0 0.1 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)
0.0 0.0 GO:0031045 dense core granule(GO:0031045)
0.0 0.1 GO:0005833 hemoglobin complex(GO:0005833)
0.0 0.0 GO:0071437 invadopodium(GO:0071437)
0.0 0.0 GO:0032449 CBM complex(GO:0032449)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.5 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
0.1 0.3 GO:0043184 vascular endothelial growth factor receptor 2 binding(GO:0043184)
0.1 0.3 GO:0016362 activin receptor activity, type II(GO:0016362)
0.1 0.2 GO:0003680 AT DNA binding(GO:0003680)
0.1 0.2 GO:0070324 thyroid hormone binding(GO:0070324)
0.1 0.4 GO:0043522 leucine zipper domain binding(GO:0043522)
0.1 0.3 GO:0004111 creatine kinase activity(GO:0004111)
0.1 0.2 GO:0005172 vascular endothelial growth factor receptor binding(GO:0005172)
0.1 0.3 GO:0034237 protein kinase A regulatory subunit binding(GO:0034237)
0.1 0.2 GO:0070097 delta-catenin binding(GO:0070097)
0.1 0.8 GO:0031490 chromatin DNA binding(GO:0031490)
0.0 0.1 GO:0004939 beta-adrenergic receptor activity(GO:0004939)
0.0 0.1 GO:0015194 L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.0 0.1 GO:0008332 low voltage-gated calcium channel activity(GO:0008332)
0.0 0.2 GO:0005010 insulin-like growth factor-activated receptor activity(GO:0005010)
0.0 0.2 GO:0008504 monoamine transmembrane transporter activity(GO:0008504)
0.0 0.1 GO:0000268 peroxisome targeting sequence binding(GO:0000268)
0.0 0.1 GO:0004829 threonine-tRNA ligase activity(GO:0004829)
0.0 0.3 GO:0017075 syntaxin-1 binding(GO:0017075)
0.0 0.1 GO:0001849 complement component C1q binding(GO:0001849)
0.0 0.1 GO:0048027 mRNA 5'-UTR binding(GO:0048027)
0.0 0.1 GO:0070644 vitamin D response element binding(GO:0070644)
0.0 0.1 GO:0004768 stearoyl-CoA 9-desaturase activity(GO:0004768) acyl-CoA desaturase activity(GO:0016215)
0.0 0.1 GO:0004427 inorganic diphosphatase activity(GO:0004427)
0.0 0.1 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.0 0.3 GO:0031078 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041) histone deacetylase activity (H4-K16 specific)(GO:0034739) NAD-dependent histone deacetylase activity (H4-K16 specific)(GO:0046970)
0.0 0.1 GO:0035184 histone threonine kinase activity(GO:0035184)
0.0 0.1 GO:0047631 ADP-ribose diphosphatase activity(GO:0047631)
0.0 0.1 GO:0035197 siRNA binding(GO:0035197)
0.0 0.2 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0 0.2 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.0 0.2 GO:0001085 RNA polymerase II transcription factor binding(GO:0001085)
0.0 0.1 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.0 0.1 GO:0042289 MHC class II protein binding(GO:0042289)
0.0 0.1 GO:0000982 transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0000982) transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077) transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.0 0.1 GO:0004911 interleukin-2 receptor activity(GO:0004911)
0.0 0.1 GO:0004792 thiosulfate sulfurtransferase activity(GO:0004792)
0.0 0.1 GO:0035014 phosphatidylinositol 3-kinase regulator activity(GO:0035014)
0.0 0.1 GO:0052659 inositol-1,4,5-trisphosphate 5-phosphatase activity(GO:0052658) inositol-1,3,4,5-tetrakisphosphate 5-phosphatase activity(GO:0052659)
0.0 0.1 GO:0016509 long-chain-3-hydroxyacyl-CoA dehydrogenase activity(GO:0016509)
0.0 0.1 GO:0005148 prolactin receptor binding(GO:0005148)
0.0 0.1 GO:0004090 carbonyl reductase (NADPH) activity(GO:0004090)
0.0 0.4 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0 0.0 GO:0008179 adenylate cyclase binding(GO:0008179)
0.0 0.1 GO:0070696 transmembrane receptor protein serine/threonine kinase binding(GO:0070696)
0.0 0.1 GO:0000977 RNA polymerase II regulatory region sequence-specific DNA binding(GO:0000977) RNA polymerase II regulatory region DNA binding(GO:0001012)
0.0 0.1 GO:0005250 A-type (transient outward) potassium channel activity(GO:0005250)
0.0 0.1 GO:0008294 calcium- and calmodulin-responsive adenylate cyclase activity(GO:0008294)
0.0 0.1 GO:0004563 beta-N-acetylhexosaminidase activity(GO:0004563)
0.0 0.1 GO:0033743 peptide-methionine (R)-S-oxide reductase activity(GO:0033743)
0.0 0.1 GO:0031177 phosphopantetheine binding(GO:0031177)
0.0 0.1 GO:0010521 telomerase inhibitor activity(GO:0010521)
0.0 0.2 GO:0033613 activating transcription factor binding(GO:0033613)
0.0 0.1 GO:0016941 natriuretic peptide receptor activity(GO:0016941)
0.0 0.0 GO:0005025 transforming growth factor beta receptor activity, type I(GO:0005025)
0.0 0.1 GO:0047184 1-acylglycerophosphocholine O-acyltransferase activity(GO:0047184)
0.0 0.1 GO:0004596 peptide alpha-N-acetyltransferase activity(GO:0004596)
0.0 0.1 GO:0005346 purine ribonucleotide transmembrane transporter activity(GO:0005346)
0.0 0.1 GO:0004703 G-protein coupled receptor kinase activity(GO:0004703)
0.0 0.1 GO:0010485 H4 histone acetyltransferase activity(GO:0010485)
0.0 0.1 GO:0030306 ADP-ribosylation factor binding(GO:0030306)
0.0 0.1 GO:0032450 maltose alpha-glucosidase activity(GO:0032450)
0.0 0.1 GO:0004791 thioredoxin-disulfide reductase activity(GO:0004791)
0.0 0.0 GO:0004999 vasoactive intestinal polypeptide receptor activity(GO:0004999)
0.0 0.1 GO:0016812 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides(GO:0016812)
0.0 0.2 GO:0048185 activin binding(GO:0048185)
0.0 0.1 GO:0032794 GTPase activating protein binding(GO:0032794)
0.0 0.1 GO:0004505 phenylalanine 4-monooxygenase activity(GO:0004505)
0.0 0.1 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.0 0.1 GO:0031491 nucleosome binding(GO:0031491)
0.0 0.1 GO:0008273 calcium, potassium:sodium antiporter activity(GO:0008273)
0.0 0.0 GO:0008321 Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.0 0.1 GO:0004035 alkaline phosphatase activity(GO:0004035)
0.0 0.2 GO:0005527 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.0 0.1 GO:0015385 sodium:proton antiporter activity(GO:0015385)
0.0 0.0 GO:0019863 IgE binding(GO:0019863)
0.0 0.2 GO:0019841 retinol binding(GO:0019841)
0.0 0.1 GO:0061133 endopeptidase activator activity(GO:0061133)
0.0 0.1 GO:0016416 carnitine O-palmitoyltransferase activity(GO:0004095) O-palmitoyltransferase activity(GO:0016416)
0.0 0.0 GO:0004351 glutamate decarboxylase activity(GO:0004351)
0.0 0.0 GO:0047623 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.0 0.1 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.0 0.2 GO:0042605 peptide antigen binding(GO:0042605)
0.0 0.1 GO:0004994 somatostatin receptor activity(GO:0004994)
0.0 0.0 GO:0005152 interleukin-1 receptor antagonist activity(GO:0005152)
0.0 0.1 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.0 0.0 GO:0070548 L-glutamine aminotransferase activity(GO:0070548)
0.0 0.1 GO:0004704 NF-kappaB-inducing kinase activity(GO:0004704)
0.0 0.1 GO:0008508 bile acid:sodium symporter activity(GO:0008508)
0.0 0.1 GO:0005315 inorganic phosphate transmembrane transporter activity(GO:0005315)
0.0 0.0 GO:0016748 succinyltransferase activity(GO:0016748)
0.0 0.0 GO:0047894 flavonol 3-sulfotransferase activity(GO:0047894)
0.0 0.0 GO:0004873 asialoglycoprotein receptor activity(GO:0004873)
0.0 0.0 GO:0070576 vitamin D 24-hydroxylase activity(GO:0070576)
0.0 0.0 GO:0046923 ER retention sequence binding(GO:0046923)
0.0 0.1 GO:0045499 chemorepellent activity(GO:0045499)
0.0 0.1 GO:0004016 adenylate cyclase activity(GO:0004016)
0.0 0.0 GO:0002162 dystroglycan binding(GO:0002162)
0.0 0.1 GO:0015220 choline transmembrane transporter activity(GO:0015220)
0.0 0.0 GO:0003910 DNA ligase activity(GO:0003909) DNA ligase (ATP) activity(GO:0003910)
0.0 0.1 GO:0046934 phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) phosphatidylinositol bisphosphate kinase activity(GO:0052813)
0.0 0.0 GO:0017162 aryl hydrocarbon receptor binding(GO:0017162)
0.0 0.1 GO:0001609 G-protein coupled adenosine receptor activity(GO:0001609)
0.0 0.1 GO:0043140 ATP-dependent 3'-5' DNA helicase activity(GO:0043140)
0.0 0.0 GO:0019797 procollagen-proline 3-dioxygenase activity(GO:0019797) peptidyl-proline 3-dioxygenase activity(GO:0031544)
0.0 0.0 GO:0004311 farnesyltranstransferase activity(GO:0004311)
0.0 0.2 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.0 0.1 GO:0016175 superoxide-generating NADPH oxidase activity(GO:0016175)
0.0 0.0 GO:0031014 troponin T binding(GO:0031014)
0.0 0.0 GO:0031821 G-protein coupled serotonin receptor binding(GO:0031821)
0.0 0.7 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.0 0.1 GO:0004652 polynucleotide adenylyltransferase activity(GO:0004652)
0.0 0.0 GO:0050265 RNA uridylyltransferase activity(GO:0050265)
0.0 0.0 GO:0016909 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.0 0.1 GO:0070290 N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.0 0.1 GO:0042043 neurexin family protein binding(GO:0042043)
0.0 0.1 GO:0043395 heparan sulfate proteoglycan binding(GO:0043395)
0.0 0.1 GO:0051636 obsolete Gram-negative bacterial cell surface binding(GO:0051636)
0.0 0.0 GO:0043024 ribosomal small subunit binding(GO:0043024)
0.0 0.1 GO:0019864 IgG binding(GO:0019864)
0.0 0.0 GO:0044020 histone methyltransferase activity (H4-R3 specific)(GO:0044020)
0.0 0.1 GO:0005110 frizzled-2 binding(GO:0005110)
0.0 0.0 GO:0008061 chitin binding(GO:0008061)
0.0 0.0 GO:0005113 patched binding(GO:0005113)
0.0 0.0 GO:0042156 obsolete zinc-mediated transcriptional activator activity(GO:0042156)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.4 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.0 1.0 PID RAC1 REG PATHWAY Regulation of RAC1 activity
0.0 0.2 ST PAC1 RECEPTOR PATHWAY PAC1 Receptor Pathway
0.0 0.0 PID ERBB4 PATHWAY ErbB4 signaling events
0.0 0.2 SA PTEN PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.0 0.3 PID TCR JNK PATHWAY JNK signaling in the CD4+ TCR pathway
0.0 0.1 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0 0.3 ST GA12 PATHWAY G alpha 12 Pathway
0.0 0.1 PID SYNDECAN 2 PATHWAY Syndecan-2-mediated signaling events
0.0 0.4 PID ALK1 PATHWAY ALK1 signaling events
0.0 0.1 PID EPO PATHWAY EPO signaling pathway
0.0 0.6 PID CERAMIDE PATHWAY Ceramide signaling pathway
0.0 0.1 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events
0.0 0.2 PID LPA4 PATHWAY LPA4-mediated signaling events
0.0 0.0 PID S1P S1P2 PATHWAY S1P2 pathway
0.0 0.0 PID MET PATHWAY Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)
0.0 0.1 PID PDGFRA PATHWAY PDGFR-alpha signaling pathway
0.0 0.1 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.4 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.0 0.4 REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS Genes involved in Tandem pore domain potassium channels
0.0 0.4 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.0 0.3 REACTOME DCC MEDIATED ATTRACTIVE SIGNALING Genes involved in DCC mediated attractive signaling
0.0 0.3 REACTOME ADENYLATE CYCLASE INHIBITORY PATHWAY Genes involved in Adenylate cyclase inhibitory pathway
0.0 0.2 REACTOME PKA MEDIATED PHOSPHORYLATION OF CREB Genes involved in PKA-mediated phosphorylation of CREB
0.0 0.0 REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.0 0.1 REACTOME THE ROLE OF NEF IN HIV1 REPLICATION AND DISEASE PATHOGENESIS Genes involved in The role of Nef in HIV-1 replication and disease pathogenesis
0.0 0.1 REACTOME G PROTEIN BETA GAMMA SIGNALLING Genes involved in G-protein beta:gamma signalling
0.0 0.2 REACTOME ASSOCIATION OF LICENSING FACTORS WITH THE PRE REPLICATIVE COMPLEX Genes involved in Association of licensing factors with the pre-replicative complex
0.0 0.2 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
0.0 0.2 REACTOME NFKB ACTIVATION THROUGH FADD RIP1 PATHWAY MEDIATED BY CASPASE 8 AND10 Genes involved in NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10
0.0 0.2 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.0 0.3 REACTOME CYTOSOLIC TRNA AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation
0.0 0.2 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.0 0.1 REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.0 0.1 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.0 0.4 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.0 0.4 REACTOME RNA POL III TRANSCRIPTION Genes involved in RNA Polymerase III Transcription
0.0 0.1 REACTOME FORMATION OF TRANSCRIPTION COUPLED NER TC NER REPAIR COMPLEX Genes involved in Formation of transcription-coupled NER (TC-NER) repair complex
0.0 0.0 REACTOME SPRY REGULATION OF FGF SIGNALING Genes involved in Spry regulation of FGF signaling
0.0 0.1 REACTOME VIRAL MESSENGER RNA SYNTHESIS Genes involved in Viral Messenger RNA Synthesis
0.0 0.0 REACTOME NEP NS2 INTERACTS WITH THE CELLULAR EXPORT MACHINERY Genes involved in NEP/NS2 Interacts with the Cellular Export Machinery
0.0 0.2 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.0 0.2 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.0 0.3 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.0 0.1 REACTOME REGULATION OF KIT SIGNALING Genes involved in Regulation of KIT signaling
0.0 0.2 REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.0 0.0 REACTOME PEPTIDE CHAIN ELONGATION Genes involved in Peptide chain elongation
0.0 0.0 REACTOME G PROTEIN ACTIVATION Genes involved in G-protein activation
0.0 0.1 REACTOME THROMBIN SIGNALLING THROUGH PROTEINASE ACTIVATED RECEPTORS PARS Genes involved in Thrombin signalling through proteinase activated receptors (PARs)
0.0 0.2 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.0 0.2 REACTOME REGULATION OF SIGNALING BY CBL Genes involved in Regulation of signaling by CBL