Project

ENCODE: H3K4me1 ChIP-Seq of primary human cells

Navigation

Downloads

Results for SIX1_SIX3_SIX2

Z-value: 3.50

Motif logo

Transcription factors associated with SIX1_SIX3_SIX2

Gene Symbol	Gene ID	Gene Info
SIX1 Ensembl NCBI GeneCards UniProt	ENSG00000126778.7	SIX homeobox 1
SIX3 Ensembl NCBI GeneCards UniProt	ENSG00000138083.3	SIX homeobox 3
SIX2 Ensembl NCBI GeneCards UniProt	ENSG00000170577.7	SIX homeobox 2

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE	Gene	Distance	Association probability	Pearson corr. coef.	P-value	Plot
chr14_61115792_61115951	SIX1	309	0.913545	-0.76	1.8e-02	Click!
chr14_61104001_61104152	SIX1	12104	0.204564	-0.71	3.1e-02	Click!
chr14_61115485_61115674	SIX1	601	0.774534	-0.67	4.9e-02	Click!
chr14_61123493_61123679	SIX1	1391	0.473380	-0.66	5.5e-02	Click!
chr14_61115062_61115213	SIX1	1043	0.576889	0.58	1.0e-01	Click!
chr2_45417634_45417785	SIX2	181140	0.031642	-0.89	1.3e-03	Click!
chr2_45396414_45396565	SIX2	159920	0.039282	-0.85	3.5e-03	Click!
chr2_45465055_45465238	SIX2	228577	0.020761	-0.84	4.7e-03	Click!
chr2_45465707_45466004	SIX2	229286	0.020641	-0.83	5.9e-03	Click!
chr2_45359902_45360053	SIX2	123408	0.059882	-0.82	6.5e-03	Click!
chr2_45168640_45168903	SIX3	131	0.505796	0.02	9.6e-01	Click!

Activity of the SIX1_SIX3_SIX2 motif across conditions

Conditions sorted by the z-value of the SIX1_SIX3_SIX2 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE)	Target Score	Top associated gene	Gene Info	Distance of CRE to TSS	CRE/Gene association probability
chr4_109044873_109045024	1.36	LEF1	lymphoid enhancer-binding factor 1	42509	0.16
chr10_11273304_11273484	1.31	RP3-323N1.2		60055	0.12
chr2_162059217_162059368	1.21	TANK	TRAF family member-associated NFKB activator	21134	0.19
chr2_12656490_12656641	1.21	ENSG00000207183	.	104938	0.08
chr16_84802159_84802310	1.20	USP10	ubiquitin specific peptidase 10	361	0.89
chr7_115362895_115363046	1.16	ENSG00000199224	.	110457	0.07
chr17_55677929_55678185	1.15	RP11-118E18.4		7716	0.21
chr14_98871416_98871598	1.14	ENSG00000241757	.	53506	0.16
chr6_143865508_143865659	1.12	PHACTR2	phosphatase and actin regulator 2	7601	0.17
chr1_226869309_226869761	1.09	ITPKB-IT1	ITPKB intronic transcript 1 (non-protein coding)	6767	0.22
chr12_918477_918628	1.09	ENSG00000221439	.	28253	0.18
chr8_129557413_129557564	1.08	ENSG00000221351	.	274552	0.01
chr2_173361835_173362001	1.06	ITGA6	integrin, alpha 6	9228	0.17
chr14_61888399_61888550	1.00	PRKCH	protein kinase C, eta	20802	0.23
chr1_183621325_183621544	0.97	APOBEC4	apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 4 (putative)	1014	0.52
chr12_46114202_46114485	0.95	ARID2	AT rich interactive domain 2 (ARID, RFX-like)	9105	0.31
chr14_50448105_50448256	0.95	C14orf182	chromosome 14 open reading frame 182	26058	0.15
chr1_110100337_110100521	0.95	GNAI3	guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3	9196	0.09
chr6_70524527_70524678	0.95	LMBRD1	LMBR1 domain containing 1	17599	0.26
chr11_63309933_63310090	0.95	RARRES3	retinoic acid receptor responder (tazarotene induced) 3	4143	0.18
chr14_61799545_61799696	0.95	PRKCH	protein kinase C, eta	5989	0.21
chr5_61582999_61583341	0.94	KIF2A	kinesin heavy chain member 2A	18819	0.25
chr12_12591963_12592114	0.93	LOH12CR1	loss of heterozygosity, 12, chromosomal region 1	81686	0.07
chr20_32592265_32592477	0.92	RALY	RALY heterogeneous nuclear ribonucleoprotein	10612	0.21
chr6_138271737_138271889	0.92	RP11-356I2.4		82443	0.09
chr8_97838422_97838573	0.92	CPQ	carboxypeptidase Q	65029	0.15
chr10_26738518_26738691	0.91	APBB1IP	amyloid beta (A4) precursor protein-binding, family B, member 1 interacting protein	11250	0.27
chr13_74288455_74288993	0.91	KLF12	Kruppel-like factor 12	280462	0.01
chr14_61847122_61847471	0.91	PRKCH	protein kinase C, eta	10116	0.24
chr17_40289887_40290120	0.90	RAB5C	RAB5C, member RAS oncogene family	1501	0.23
chr8_29958239_29958543	0.89	LEPROTL1	leptin receptor overlapping transcript-like 1	1065	0.45
chr13_30512291_30512563	0.89	LINC00572	long intergenic non-protein coding RNA 572	11639	0.29
chr3_67786694_67786845	0.89	SUCLG2	succinate-CoA ligase, GDP-forming, beta subunit	81731	0.11
chr1_224001140_224001345	0.88	TP53BP2	tumor protein p53 binding protein, 2	788	0.74
chr16_68103973_68104124	0.88	ENSG00000221789	.	14261	0.09
chr16_68165701_68165963	0.88	NFATC3	nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3	8899	0.12
chr10_33405886_33406153	0.88	ENSG00000263576	.	18455	0.22
chr1_89731774_89731925	0.88	GBP5	guanylate binding protein 5	4697	0.21
chr3_42680360_42680700	0.88	ZBTB47	zinc finger and BTB domain containing 47	14646	0.1
chr3_32498389_32498575	0.87	CMTM6	CKLF-like MARVEL transmembrane domain containing 6	46418	0.14
chrX_128901533_128901839	0.87	SASH3	SAM and SH3 domain containing 3	12274	0.19
chr7_130637518_130637669	0.86	LINC-PINT	long intergenic non-protein coding RNA, p53 induced transcript	31275	0.2
chr16_68113187_68113581	0.86	NFATC3	nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3	5863	0.11
chr6_40756517_40756668	0.85	LRFN2	leucine rich repeat and fibronectin type III domain containing 2	201388	0.02
chr4_109059391_109059542	0.85	LEF1	lymphoid enhancer-binding factor 1	27991	0.19
chr5_100189680_100189848	0.85	ENSG00000221263	.	37495	0.19
chr17_71719154_71719371	0.85	SDK2	sidekick cell adhesion molecule 2	79034	0.1
chr2_30478275_30478623	0.84	LBH	limb bud and heart development	23403	0.22
chr6_159603530_159603681	0.83	RP11-13P5.2		12566	0.2
chr22_30671598_30671900	0.83	OSM	oncostatin M	8920	0.1
chr2_158287576_158287811	0.83	CYTIP	cytohesin 1 interacting protein	8233	0.23
chr6_106097038_106097311	0.82	PREP	prolyl endopeptidase	246215	0.02
chr1_89775651_89775949	0.81	GBP5	guanylate binding protein 5	37256	0.14
chr17_33370278_33370429	0.81	RFFL	ring finger and FYVE-like domain containing E3 ubiquitin protein ligase	983	0.42
chr2_68994725_68994973	0.81	ARHGAP25	Rho GTPase activating protein 25	7084	0.26
chr5_130730727_130730878	0.81	CDC42SE2	CDC42 small effector 2	9503	0.3
chr17_10606742_10606929	0.81	ADPRM	ADP-ribose/CDP-alcohol diphosphatase, manganese-dependent	1382	0.32
chr17_40859849_40860000	0.80	CTD-3193K9.3		8440	0.09
chr6_159338798_159338949	0.80	ENSG00000223191	.	8730	0.2
chr11_118267832_118267983	0.80	ATP5L	ATP synthase, H+ transporting, mitochondrial Fo complex, subunit G	3962	0.12
chr18_2644828_2644979	0.80	ENSG00000200875	.	4963	0.17
chr3_151926614_151926765	0.80	MBNL1	muscleblind-like splicing regulator 1	59140	0.13
chr2_106390945_106391331	0.79	NCK2	NCK adaptor protein 2	28950	0.23
chr8_128189492_128189643	0.79	POU5F1B	POU class 5 homeobox 1B	236968	0.02
chr5_55898794_55898945	0.79	AC022431.2	Homo sapiens uncharacterized LOC101928448 (LOC101928448), mRNA.	3190	0.32
chr1_198588112_198588263	0.79	PTPRC	protein tyrosine phosphatase, receptor type, C	19614	0.23
chr5_80299716_80299867	0.79	CTC-459I6.1		43065	0.16
chr15_77158378_77158529	0.79	SCAPER	S-phase cyclin A-associated protein in the ER	4168	0.29
chr12_92796090_92796306	0.79	RP11-693J15.4		19109	0.18
chr10_73988301_73988452	0.78	ENSG00000200170	.	7866	0.14
chr1_151026641_151026888	0.78	MLLT11	myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11	3470	0.1
chr21_34699167_34699460	0.78	IFNAR1	interferon (alpha, beta and omega) receptor 1	2035	0.31
chr16_47002248_47002399	0.78	DNAJA2	DnaJ (Hsp40) homolog, subfamily A, member 2	4531	0.23
chr9_77767149_77767402	0.78	ENSG00000200041	.	29262	0.16
chr4_185150814_185151001	0.78	ENPP6	ectonucleotide pyrophosphatase/phosphodiesterase 6	8524	0.22
chr9_112713247_112713398	0.77	PALM2	paralemmin 2	84011	0.09
chr11_109973829_109973980	0.77	ZC3H12C	zinc finger CCCH-type containing 12C	9817	0.32
chr6_143132803_143132984	0.77	HIVEP2	human immunodeficiency virus type I enhancer binding protein 2	25291	0.23
chr1_159016145_159016303	0.77	ENSG00000265589	.	12815	0.17
chr6_36077167_36077664	0.77	MAPK13	mitogen-activated protein kinase 13	20683	0.16
chr9_130792035_130792335	0.77	RP11-379C10.1		27456	0.09
chr16_56972600_56972821	0.76	HERPUD1	homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1	451	0.65
chr12_123712025_123712176	0.76	MPHOSPH9	M-phase phosphoprotein 9	2893	0.18
chr15_63967258_63967409	0.76	RP11-317G6.1		12	0.98
chr3_48968098_48968249	0.76	ARIH2OS	ariadne homolog 2 opposite strand	11355	0.1
chr4_40216724_40216947	0.76	RHOH	ras homolog family member H	14871	0.21
chr9_134142900_134143064	0.76	FAM78A	family with sequence similarity 78, member A	2898	0.24
chr2_136447668_136447819	0.75	R3HDM1	R3H domain containing 1	14775	0.17
chr3_197573971_197574122	0.75	LRCH3	leucine-rich repeats and calponin homology (CH) domain containing 3	784	0.62
chr6_4819217_4819368	0.75	CDYL	chromodomain protein, Y-like	17040	0.24
chrX_57317675_57317826	0.75	FAAH2	fatty acid amide hydrolase 2	4611	0.34
chr16_53471043_53471490	0.75	RBL2	retinoblastoma-like 2 (p130)	1735	0.31
chr4_114824606_114824763	0.75	RP11-26P13.2		39728	0.2
chr6_130531289_130531440	0.75	SAMD3	sterile alpha motif domain containing 3	5071	0.3
chr2_38817165_38817316	0.74	HNRNPLL	heterogeneous nuclear ribonucleoprotein L-like	9928	0.2
chr17_66345557_66345739	0.74	ARSG	arylsulfatase G	57989	0.1
chrX_13756263_13756416	0.74	OFD1	oral-facial-digital syndrome 1	3475	0.21
chr7_65361163_65361314	0.74	VKORC1L1	vitamin K epoxide reductase complex, subunit 1-like 1	22882	0.17
chr3_4537749_4538010	0.74	ITPR1	inositol 1,4,5-trisphosphate receptor, type 1	2645	0.27
chr12_68570081_68570404	0.73	IFNG	interferon, gamma	16715	0.23
chr6_138196538_138196689	0.73	RP11-356I2.4		7243	0.23
chr2_208390268_208390490	0.73	CREB1	cAMP responsive element binding protein 1	4082	0.24
chr13_50667366_50667517	0.73	DLEU1	deleted in lymphocytic leukemia 1 (non-protein coding)	11134	0.19
chr14_92331009_92331160	0.73	TC2N	tandem C2 domains, nuclear	2789	0.28
chr17_63042983_63043134	0.72	RP11-583F2.5		4969	0.2
chr4_108994694_108994845	0.72	HADH	hydroxyacyl-CoA dehydrogenase	68978	0.1
chr17_37931145_37931296	0.72	IKZF3	IKAROS family zinc finger 3 (Aiolos)	3258	0.18
chr11_85771046_85771289	0.72	PICALM	phosphatidylinositol binding clathrin assembly protein	8655	0.23
chrY_16455920_16456071	0.72	ENSG00000266220	.	91824	0.1
chr2_202102817_202103075	0.72	CASP8	caspase 8, apoptosis-related cysteine peptidase	4717	0.21
chr12_29255913_29256179	0.72	ENSG00000222481	.	17769	0.25
chr7_6659621_6659772	0.72	ZNF853	zinc finger protein 853	4448	0.14
chr1_155511274_155511512	0.71	ENSG00000235919	.	20471	0.14
chr1_73100299_73100450	0.71	ENSG00000212366	.	83078	0.12
chr19_47694730_47694881	0.71	ENSG00000265134	.	35394	0.11
chr7_50415751_50415902	0.71	IKZF1	IKAROS family zinc finger 1 (Ikaros)	48581	0.16
chr3_152018760_152019009	0.71	MBNL1	muscleblind-like splicing regulator 1	897	0.64
chr9_77719485_77719636	0.71	OSTF1	osteoclast stimulating factor 1	16101	0.17
chr21_30667296_30667447	0.71	BACH1	BTB and CNC homology 1, basic leucine zipper transcription factor 1	3821	0.24
chr9_75537255_75537406	0.71	ALDH1A1	aldehyde dehydrogenase 1 family, member A1	30641	0.25
chr18_2985570_2985736	0.71	LPIN2	lipin 2	2782	0.22
chr2_143943022_143943284	0.71	RP11-190J23.1		13412	0.27
chr6_106635819_106636032	0.70	RP1-134E15.3		87910	0.07
chr1_101399727_101399878	0.70	SLC30A7	solute carrier family 30 (zinc transporter), member 7	27582	0.13
chr17_7295984_7296153	0.70	TMEM256-PLSCR3	TMEM256-PLSCR3 readthrough (NMD candidate)	733	0.35
chr3_45047220_45047371	0.70	CLEC3B	C-type lectin domain family 3, member B	20380	0.14
chr1_154199766_154199917	0.70	UBAP2L	ubiquitin associated protein 2-like	2283	0.14
chr16_53494132_53494295	0.70	RBL2	retinoblastoma-like 2 (p130)	10225	0.16
chr1_226871894_226872507	0.70	ITPKB-IT1	ITPKB intronic transcript 1 (non-protein coding)	9432	0.21
chr16_84547230_84547512	0.70	TLDC1	TBC/LysM-associated domain containing 1	9007	0.18
chr4_106123977_106124128	0.70	TET2-AS1	TET2 antisense RNA 1	24832	0.2
chr1_54810117_54810268	0.70	RP5-997D24.3		59114	0.1
chr5_38453264_38453467	0.69	EGFLAM	EGF-like, fibronectin type III and laminin G domains	5007	0.18
chr18_43268903_43269487	0.69	SLC14A2	solute carrier family 14 (urea transporter), member 2	23088	0.16
chr9_117498735_117498886	0.69	TNFSF15	tumor necrosis factor (ligand) superfamily, member 15	55578	0.12
chr6_2892378_2892529	0.69	SERPINB9	serpin peptidase inhibitor, clade B (ovalbumin), member 9	11061	0.17
chr1_27945115_27945319	0.69	FGR	feline Gardner-Rasheed sarcoma viral oncogene homolog	5356	0.15
chr1_39717174_39717325	0.69	RP11-420K8.1		6072	0.2
chr12_92756626_92757039	0.69	RP11-693J15.4		58475	0.12
chr17_37950798_37951120	0.69	IKZF3	IKAROS family zinc finger 3 (Aiolos)	16481	0.14
chr2_144015517_144015791	0.68	RP11-190J23.1		85913	0.1
chr2_198034211_198034367	0.68	ANKRD44	ankyrin repeat domain 44	17544	0.21
chr12_49959554_49959705	0.68	MCRS1	microspherule protein 1	593	0.62
chr6_45462917_45463095	0.68	RUNX2	runt-related transcription factor 2	72784	0.11
chr1_62249723_62249899	0.68	ENSG00000200575	.	32280	0.16
chrX_135715704_135715855	0.68	ENSG00000233093	.	5923	0.18
chr7_148960727_148960905	0.68	ZNF783	zinc finger family member 783	1554	0.32
chr1_206556159_206556344	0.67	SRGAP2	SLIT-ROBO Rho GTPase activating protein 2	1115	0.4
chr1_168500435_168500586	0.67	XCL2	chemokine (C motif) ligand 2	12725	0.24
chr1_84630315_84630544	0.67	PRKACB	protein kinase, cAMP-dependent, catalytic, beta	51	0.99
chr5_130637450_130637601	0.67	CDC42SE2	CDC42 small effector 2	37732	0.21
chr10_124300753_124301107	0.67	DMBT1	deleted in malignant brain tumors 1	19251	0.2
chr14_98086565_98086821	0.67	ENSG00000240730	.	90183	0.1
chr14_23013063_23013415	0.67	AE000662.92	Uncharacterized protein	12295	0.1
chr20_35258679_35258929	0.67	SLA2	Src-like-adaptor 2	15480	0.12
chr2_37844931_37845082	0.66	AC006369.2		17727	0.22
chr1_100895855_100896006	0.66	ENSG00000216067	.	51599	0.12
chr17_27270891_27271054	0.66	RP11-20B24.6		842	0.4
chr6_53718701_53718852	0.66	LRRC1	leucine rich repeat containing 1	58888	0.11
chr19_42658756_42658907	0.66	CTC-378H22.2		2110	0.17
chr2_205898730_205898881	0.66	PARD3B	par-3 family cell polarity regulator beta	488082	0.01
chr1_98501171_98501322	0.66	ENSG00000225206	.	9661	0.31
chr5_75838190_75838590	0.66	IQGAP2	IQ motif containing GTPase activating protein 2	4844	0.28
chr3_12685707_12685858	0.65	ENSG00000239140	.	11549	0.18
chr7_50366365_50366566	0.65	IKZF1	IKAROS family zinc finger 1 (Ikaros)	780	0.76
chr17_47316141_47316292	0.65	PHOSPHO1	phosphatase, orphan 1	8088	0.15
chr2_169605729_169605880	0.65	CERS6-AS1	CERS6 antisense RNA 1	35494	0.17
chr9_21025987_21026269	0.65	PTPLAD2	protein tyrosine phosphatase-like A domain containing 2	5480	0.23
chrX_20238834_20238985	0.65	RPS6KA3	ribosomal protein S6 kinase, 90kDa, polypeptide 3	1832	0.4
chr6_160435877_160436181	0.65	AIRN	antisense of IGF2R non-protein coding RNA	7333	0.24
chr19_46294986_46295331	0.65	DMWD	dystrophia myotonica, WD repeat containing	537	0.56
chr20_49152431_49152666	0.65	ENSG00000239742	.	21987	0.13
chr10_103603860_103604193	0.65	KCNIP2	Kv channel interacting protein 2	349	0.86
chr14_61885871_61886022	0.64	PRKCH	protein kinase C, eta	23330	0.22
chr7_50453136_50453287	0.64	ENSG00000200815	.	49867	0.14
chr17_65384222_65384373	0.64	PITPNC1	phosphatidylinositol transfer protein, cytoplasmic 1	9215	0.14
chr2_48567395_48567695	0.64	ENSG00000251889	.	420	0.87
chr7_116646128_116646279	0.64	ST7	suppression of tumorigenicity 7	8739	0.17
chr11_70244973_70245417	0.63	CTTN	cortactin	548	0.45
chr10_126345903_126346068	0.63	FAM53B-AS1	FAM53B antisense RNA 1	46209	0.15
chr5_139502789_139502959	0.63	IGIP	IgA-inducing protein	2647	0.21
chr17_15490936_15491230	0.63	CDRT1	CMT1A duplicated region transcript 1	5639	0.14
chr5_75770925_75771240	0.63	IQGAP2	IQ motif containing GTPase activating protein 2	70833	0.11
chr4_36312605_36313014	0.63	DTHD1	death domain containing 1	27165	0.2
chrX_13268049_13268200	0.63	GS1-600G8.3		60647	0.13
chr2_149410654_149410805	0.63	EPC2	enhancer of polycomb homolog 2 (Drosophila)	7740	0.31
chr9_77707709_77707978	0.63	OSTF1	osteoclast stimulating factor 1	4384	0.21
chr10_93006478_93006693	0.63	PCGF5	polycomb group ring finger 5	26040	0.26
chr1_65408789_65408940	0.63	JAK1	Janus kinase 1	23323	0.22
chr11_66884631_66884782	0.63	KDM2A	lysine (K)-specific demethylase 2A	2034	0.3
chr2_136809392_136809630	0.63	AC093391.2		39476	0.17
chr12_106622335_106622486	0.62	RP11-651L5.2		18324	0.17
chr5_133415412_133415563	0.62	TCF7	transcription factor 7 (T-cell specific, HMG-box)	34915	0.17
chr5_79491656_79491902	0.62	ENSG00000239159	.	43629	0.13
chr1_112213429_112213580	0.62	ENSG00000201028	.	20345	0.16
chr4_154423555_154423706	0.62	KIAA0922	KIAA0922	36129	0.19
chr1_223422495_223422646	0.62	TLR5	toll-like receptor 5	105946	0.07
chr13_46741274_46741762	0.61	LCP1	lymphocyte cytosolic protein 1 (L-plastin)	1136	0.43
chr5_75769465_75769791	0.61	IQGAP2	IQ motif containing GTPase activating protein 2	69379	0.12
chr8_71052566_71052771	0.61	NCOA2	nuclear receptor coactivator 2	7953	0.25

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of SIX1_SIX3_SIX2

View svg image
View png image

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.3	1.0	GO:0010459	negative regulation of heart rate(GO:0010459)
0.3	0.9	GO:0030223	neutrophil differentiation(GO:0030223)
0.3	0.3	GO:0002513	tolerance induction to self antigen(GO:0002513)
0.3	0.8	GO:0035405	histone-threonine phosphorylation(GO:0035405)
0.3	0.5	GO:0002713	negative regulation of B cell mediated immunity(GO:0002713) negative regulation of immunoglobulin mediated immune response(GO:0002890)
0.2	0.9	GO:0032237	activation of store-operated calcium channel activity(GO:0032237) regulation of store-operated calcium channel activity(GO:1901339) positive regulation of store-operated calcium channel activity(GO:1901341)
0.2	0.7	GO:0034139	regulation of toll-like receptor 3 signaling pathway(GO:0034139)
0.2	0.9	GO:0045589	regulation of regulatory T cell differentiation(GO:0045589)
0.2	1.1	GO:0050857	positive regulation of antigen receptor-mediated signaling pathway(GO:0050857)
0.2	0.6	GO:0045066	regulatory T cell differentiation(GO:0045066)
0.2	0.2	GO:0002326	B cell lineage commitment(GO:0002326)
0.2	1.3	GO:0007172	signal complex assembly(GO:0007172)
0.2	0.7	GO:0046642	negative regulation of alpha-beta T cell proliferation(GO:0046642)
0.2	0.5	GO:0070601	centromeric sister chromatid cohesion(GO:0070601) regulation of centromeric sister chromatid cohesion(GO:0070602)
0.2	0.8	GO:0019987	obsolete negative regulation of anti-apoptosis(GO:0019987)
0.1	0.4	GO:0007571	age-dependent response to oxidative stress(GO:0001306) age-dependent general metabolic decline(GO:0007571)
0.1	0.4	GO:0070777	D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
0.1	0.7	GO:0002726	positive regulation of T cell cytokine production(GO:0002726)
0.1	0.3	GO:0001766	membrane raft polarization(GO:0001766) membrane raft distribution(GO:0031580)
0.1	0.4	GO:0003339	regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis(GO:0003339)
0.1	1.1	GO:0006491	N-glycan processing(GO:0006491)
0.1	0.4	GO:1904035	endothelial cell apoptotic process(GO:0072577) epithelial cell apoptotic process(GO:1904019) regulation of epithelial cell apoptotic process(GO:1904035) regulation of endothelial cell apoptotic process(GO:2000351)
0.1	0.4	GO:0030854	positive regulation of granulocyte differentiation(GO:0030854)
0.1	0.6	GO:0070670	response to interleukin-4(GO:0070670)
0.1	0.6	GO:0032876	regulation of DNA endoreduplication(GO:0032875) negative regulation of DNA endoreduplication(GO:0032876) DNA endoreduplication(GO:0042023)
0.1	0.4	GO:0045722	positive regulation of gluconeogenesis(GO:0045722)
0.1	1.1	GO:0000381	regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.1	0.5	GO:0090286	cytoskeletal anchoring at nuclear membrane(GO:0090286)
0.1	0.7	GO:0045059	positive thymic T cell selection(GO:0045059)
0.1	0.4	GO:0045341	MHC class I biosynthetic process(GO:0045341) regulation of MHC class I biosynthetic process(GO:0045343)
0.1	0.5	GO:0033152	immunoglobulin V(D)J recombination(GO:0033152)
0.1	0.3	GO:0048859	formation of anatomical boundary(GO:0048859)
0.1	0.3	GO:0045163	clustering of voltage-gated potassium channels(GO:0045163)
0.1	0.3	GO:0007352	zygotic specification of dorsal/ventral axis(GO:0007352)
0.1	0.5	GO:0042989	sequestering of actin monomers(GO:0042989)
0.1	0.1	GO:0030859	polarized epithelial cell differentiation(GO:0030859)
0.1	0.5	GO:0045898	regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045898)
0.1	0.3	GO:0009048	dosage compensation by inactivation of X chromosome(GO:0009048)
0.1	0.2	GO:2000114	regulation of establishment of cell polarity(GO:2000114)
0.1	0.2	GO:0002313	mature B cell differentiation involved in immune response(GO:0002313)
0.1	0.3	GO:0006296	nucleotide-excision repair, DNA incision, 5'-to lesion(GO:0006296)
0.1	0.4	GO:0017182	peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183)
0.1	0.3	GO:0032506	cytokinetic process(GO:0032506)
0.1	0.3	GO:0014889	muscle atrophy(GO:0014889)
0.1	0.8	GO:0030206	chondroitin sulfate biosynthetic process(GO:0030206)
0.1	0.3	GO:0071481	cellular response to X-ray(GO:0071481)
0.1	0.3	GO:0001743	optic placode formation(GO:0001743)
0.1	0.2	GO:0019049	evasion or tolerance of host defenses by virus(GO:0019049) avoidance of host defenses(GO:0044413) evasion or tolerance of host defenses(GO:0044415) avoidance of defenses of other organism involved in symbiotic interaction(GO:0051832) evasion or tolerance of defenses of other organism involved in symbiotic interaction(GO:0051834)
0.1	0.4	GO:0048096	chromatin-mediated maintenance of transcription(GO:0048096)
0.1	0.3	GO:0019731	antibacterial humoral response(GO:0019731)
0.1	0.3	GO:0060287	epithelial cilium movement(GO:0003351) epithelial cilium movement involved in determination of left/right asymmetry(GO:0060287)
0.1	0.3	GO:0015917	aminophospholipid transport(GO:0015917)
0.1	0.2	GO:0051220	cytoplasmic sequestering of protein(GO:0051220)
0.1	0.2	GO:0042091	interleukin-10 biosynthetic process(GO:0042091) regulation of interleukin-10 biosynthetic process(GO:0045074)
0.1	0.7	GO:0001782	B cell homeostasis(GO:0001782)
0.1	0.2	GO:0051461	corticotropin secretion(GO:0051458) regulation of corticotropin secretion(GO:0051459) positive regulation of corticotropin secretion(GO:0051461)
0.1	2.0	GO:0050690	regulation of defense response to virus by virus(GO:0050690)
0.1	0.3	GO:0034501	protein localization to kinetochore(GO:0034501)
0.1	0.8	GO:0051806	entry into host cell(GO:0030260) entry into host(GO:0044409) entry into cell of other organism involved in symbiotic interaction(GO:0051806) entry into other organism involved in symbiotic interaction(GO:0051828)
0.1	0.6	GO:0035246	peptidyl-arginine N-methylation(GO:0035246)
0.1	0.1	GO:0002282	microglial cell activation involved in immune response(GO:0002282)
0.1	0.2	GO:0034625	fatty acid elongation, monounsaturated fatty acid(GO:0034625)
0.1	0.2	GO:0090322	regulation of superoxide metabolic process(GO:0090322)
0.1	0.3	GO:0006104	succinyl-CoA metabolic process(GO:0006104)
0.1	0.2	GO:0030505	inorganic diphosphate transport(GO:0030505)
0.1	0.1	GO:0002507	tolerance induction(GO:0002507)
0.1	0.4	GO:0010832	negative regulation of myotube differentiation(GO:0010832)
0.1	0.4	GO:0002855	natural killer cell mediated cytotoxicity directed against tumor cell target(GO:0002420) natural killer cell mediated immune response to tumor cell(GO:0002423) regulation of natural killer cell mediated immune response to tumor cell(GO:0002855) positive regulation of natural killer cell mediated immune response to tumor cell(GO:0002857) regulation of natural killer cell mediated cytotoxicity directed against tumor cell target(GO:0002858) positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target(GO:0002860)
0.1	0.6	GO:0043550	regulation of lipid kinase activity(GO:0043550)
0.1	0.4	GO:0000132	establishment of mitotic spindle orientation(GO:0000132) establishment of spindle orientation(GO:0051294)
0.1	0.2	GO:0043320	natural killer cell activation involved in immune response(GO:0002323) natural killer cell degranulation(GO:0043320)
0.1	0.6	GO:0071391	cellular response to estrogen stimulus(GO:0071391)
0.1	0.4	GO:0006857	oligopeptide transport(GO:0006857)
0.1	0.3	GO:0022614	membrane to membrane docking(GO:0022614)
0.1	0.1	GO:0002839	positive regulation of response to biotic stimulus(GO:0002833) regulation of response to tumor cell(GO:0002834) positive regulation of response to tumor cell(GO:0002836) regulation of immune response to tumor cell(GO:0002837) positive regulation of immune response to tumor cell(GO:0002839)
0.1	1.0	GO:0016578	histone deubiquitination(GO:0016578)
0.1	0.1	GO:0048541	Peyer's patch development(GO:0048541)
0.1	0.2	GO:0016137	glycoside metabolic process(GO:0016137) glycoside catabolic process(GO:0016139)
0.1	0.3	GO:0002691	regulation of cellular extravasation(GO:0002691)
0.1	0.1	GO:0034122	negative regulation of toll-like receptor signaling pathway(GO:0034122)
0.1	0.3	GO:0006564	L-serine biosynthetic process(GO:0006564)
0.1	0.1	GO:0021938	ventral midline development(GO:0007418) smoothened signaling pathway involved in regulation of cerebellar granule cell precursor cell proliferation(GO:0021938)
0.1	0.2	GO:0007100	mitotic centrosome separation(GO:0007100)
0.1	0.2	GO:0002430	complement receptor mediated signaling pathway(GO:0002430)
0.1	0.2	GO:0006924	activation-induced cell death of T cells(GO:0006924)
0.1	0.1	GO:0002523	leukocyte migration involved in inflammatory response(GO:0002523)
0.1	0.3	GO:0006998	nuclear envelope organization(GO:0006998)
0.1	1.1	GO:0060330	regulation of response to interferon-gamma(GO:0060330) regulation of interferon-gamma-mediated signaling pathway(GO:0060334)
0.1	0.2	GO:0032075	positive regulation of nuclease activity(GO:0032075)
0.1	0.1	GO:0051549	regulation of keratinocyte migration(GO:0051547) positive regulation of keratinocyte migration(GO:0051549)
0.1	0.1	GO:0030252	growth hormone secretion(GO:0030252)
0.1	0.3	GO:0031936	negative regulation of chromatin silencing(GO:0031936)
0.1	0.2	GO:0006978	DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:0006978)
0.1	0.2	GO:0010447	response to acidic pH(GO:0010447)
0.1	0.1	GO:0071698	olfactory placode formation(GO:0030910) olfactory placode development(GO:0071698) olfactory placode morphogenesis(GO:0071699)
0.1	0.2	GO:0045916	negative regulation of humoral immune response(GO:0002921) negative regulation of complement activation(GO:0045916) negative regulation of protein activation cascade(GO:2000258)
0.1	0.3	GO:0043267	negative regulation of potassium ion transport(GO:0043267)
0.1	0.1	GO:0048537	mucosal-associated lymphoid tissue development(GO:0048537)
0.1	0.2	GO:0046476	glycosylceramide biosynthetic process(GO:0046476)
0.1	0.2	GO:0039656	modulation by virus of host gene expression(GO:0039656)
0.1	0.2	GO:0043518	negative regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043518) negative regulation of signal transduction by p53 class mediator(GO:1901797)
0.1	0.2	GO:0030970	retrograde protein transport, ER to cytosol(GO:0030970)
0.1	0.2	GO:0006167	AMP biosynthetic process(GO:0006167)
0.1	0.1	GO:0045064	T-helper 2 cell differentiation(GO:0045064)
0.1	0.2	GO:0045349	interferon-alpha biosynthetic process(GO:0045349) regulation of interferon-alpha biosynthetic process(GO:0045354)
0.1	0.2	GO:0072224	metanephric glomerulus development(GO:0072224) metanephric glomerulus vasculature development(GO:0072239)
0.1	0.1	GO:0060218	hematopoietic stem cell differentiation(GO:0060218)
0.1	0.2	GO:0035455	response to interferon-alpha(GO:0035455)
0.1	0.6	GO:0098927	early endosome to late endosome transport(GO:0045022) vesicle-mediated transport between endosomal compartments(GO:0098927)
0.1	0.1	GO:0048548	regulation of pinocytosis(GO:0048548)
0.1	0.3	GO:0015904	tetracycline transport(GO:0015904)
0.1	0.2	GO:0034661	ncRNA catabolic process(GO:0034661)
0.1	0.1	GO:0034638	phosphatidylcholine catabolic process(GO:0034638)
0.1	0.2	GO:0002002	regulation of angiotensin levels in blood(GO:0002002)
0.1	0.2	GO:0060159	regulation of dopamine receptor signaling pathway(GO:0060159)
0.1	0.3	GO:0060123	regulation of growth hormone secretion(GO:0060123)
0.1	0.2	GO:0007095	mitotic G2 DNA damage checkpoint(GO:0007095)
0.1	0.1	GO:0001831	trophectodermal cellular morphogenesis(GO:0001831)
0.1	0.1	GO:0071801	regulation of podosome assembly(GO:0071801) positive regulation of podosome assembly(GO:0071803)
0.1	0.2	GO:0010867	positive regulation of triglyceride biosynthetic process(GO:0010867)
0.1	0.1	GO:0002862	negative regulation of inflammatory response to antigenic stimulus(GO:0002862)
0.1	0.2	GO:0032695	negative regulation of interleukin-12 production(GO:0032695)
0.1	0.4	GO:0003084	positive regulation of systemic arterial blood pressure(GO:0003084)
0.1	0.2	GO:0071636	positive regulation of transforming growth factor beta production(GO:0071636)
0.1	0.3	GO:0019885	antigen processing and presentation of endogenous peptide antigen(GO:0002483) antigen processing and presentation of endogenous peptide antigen via MHC class I(GO:0019885)
0.0	0.1	GO:0001911	negative regulation of leukocyte mediated cytotoxicity(GO:0001911)
0.0	0.0	GO:0033622	integrin activation(GO:0033622)
0.0	0.2	GO:0007256	activation of JNKK activity(GO:0007256)
0.0	0.1	GO:0009414	response to water deprivation(GO:0009414) response to water(GO:0009415)
0.0	0.2	GO:0006498	N-terminal protein lipidation(GO:0006498)
0.0	0.5	GO:0002286	T cell activation involved in immune response(GO:0002286)
0.0	0.1	GO:0018076	N-terminal peptidyl-lysine acetylation(GO:0018076)
0.0	0.8	GO:0034199	activation of protein kinase A activity(GO:0034199)
0.0	1.8	GO:0016579	protein deubiquitination(GO:0016579)
0.0	0.2	GO:0060437	lung growth(GO:0060437)
0.0	0.1	GO:0042996	regulation of Golgi to plasma membrane protein transport(GO:0042996)
0.0	0.1	GO:0043368	positive T cell selection(GO:0043368)
0.0	0.2	GO:0010642	negative regulation of platelet-derived growth factor receptor signaling pathway(GO:0010642)
0.0	0.3	GO:0071157	negative regulation of cell cycle arrest(GO:0071157)
0.0	0.2	GO:2001234	negative regulation of mitochondrion organization(GO:0010823) negative regulation of release of cytochrome c from mitochondria(GO:0090201) negative regulation of apoptotic signaling pathway(GO:2001234)
0.0	0.1	GO:0010626	regulation of Schwann cell proliferation(GO:0010624) negative regulation of Schwann cell proliferation(GO:0010626)
0.0	0.1	GO:0090400	stress-induced premature senescence(GO:0090400)
0.0	0.0	GO:0046477	glycosylceramide catabolic process(GO:0046477)
0.0	0.3	GO:0033504	floor plate development(GO:0033504)
0.0	0.3	GO:1901976	regulation of cell cycle checkpoint(GO:1901976)
0.0	0.4	GO:0033631	cell-cell adhesion mediated by integrin(GO:0033631)
0.0	0.1	GO:0046940	nucleoside monophosphate phosphorylation(GO:0046940)
0.0	0.1	GO:0010761	fibroblast migration(GO:0010761)
0.0	0.1	GO:0010592	positive regulation of lamellipodium assembly(GO:0010592) positive regulation of lamellipodium organization(GO:1902745)
0.0	0.2	GO:0000098	sulfur amino acid catabolic process(GO:0000098)
0.0	0.3	GO:0016556	mRNA modification(GO:0016556)
0.0	0.1	GO:0048143	astrocyte activation(GO:0048143)
0.0	0.0	GO:0000375	RNA splicing, via transesterification reactions(GO:0000375)
0.0	0.4	GO:0048208	vesicle targeting, rough ER to cis-Golgi(GO:0048207) COPII vesicle coating(GO:0048208) COPII-coated vesicle budding(GO:0090114)
0.0	0.2	GO:0032926	negative regulation of activin receptor signaling pathway(GO:0032926)
0.0	0.2	GO:0048261	negative regulation of receptor-mediated endocytosis(GO:0048261)
0.0	0.3	GO:0032464	positive regulation of protein homooligomerization(GO:0032464)
0.0	0.2	GO:0018202	peptidyl-histidine phosphorylation(GO:0018106) peptidyl-histidine modification(GO:0018202)
0.0	0.2	GO:0032966	negative regulation of collagen biosynthetic process(GO:0032966)
0.0	0.1	GO:0002903	negative regulation of B cell apoptotic process(GO:0002903)
0.0	0.4	GO:0045197	establishment or maintenance of epithelial cell apical/basal polarity(GO:0045197)
0.0	0.0	GO:0006927	obsolete transformed cell apoptotic process(GO:0006927)
0.0	0.3	GO:0070198	protein localization to chromosome, telomeric region(GO:0070198)
0.0	0.1	GO:0010457	centriole-centriole cohesion(GO:0010457)
0.0	0.1	GO:0045603	positive regulation of endothelial cell differentiation(GO:0045603)
0.0	0.7	GO:0045730	respiratory burst(GO:0045730)
0.0	0.1	GO:0032641	lymphotoxin A production(GO:0032641) lymphotoxin A biosynthetic process(GO:0042109)
0.0	0.6	GO:0007052	mitotic spindle organization(GO:0007052)
0.0	0.2	GO:0003056	regulation of vascular smooth muscle contraction(GO:0003056)
0.0	0.2	GO:0045040	outer mitochondrial membrane organization(GO:0007008) protein import into mitochondrial outer membrane(GO:0045040)
0.0	0.2	GO:0010507	negative regulation of autophagy(GO:0010507)
0.0	0.1	GO:0032232	negative regulation of actin filament bundle assembly(GO:0032232) negative regulation of stress fiber assembly(GO:0051497)
0.0	0.2	GO:0050869	negative regulation of B cell activation(GO:0050869)
0.0	0.2	GO:0031340	positive regulation of vesicle fusion(GO:0031340)
0.0	0.4	GO:0007413	axonal fasciculation(GO:0007413)
0.0	0.4	GO:0010390	histone monoubiquitination(GO:0010390)
0.0	0.3	GO:0007253	cytoplasmic sequestering of NF-kappaB(GO:0007253)
0.0	0.1	GO:1901522	positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus(GO:1901522)
0.0	0.2	GO:0042508	tyrosine phosphorylation of Stat1 protein(GO:0042508)
0.0	0.2	GO:0043628	ncRNA 3'-end processing(GO:0043628)
0.0	0.1	GO:0015801	aromatic amino acid transport(GO:0015801)
0.0	0.0	GO:0031274	pseudopodium assembly(GO:0031269) regulation of pseudopodium assembly(GO:0031272) positive regulation of pseudopodium assembly(GO:0031274)
0.0	0.1	GO:0035269	protein mannosylation(GO:0035268) protein O-linked mannosylation(GO:0035269) mannosylation(GO:0097502)
0.0	0.1	GO:0043983	histone H4-K12 acetylation(GO:0043983)
0.0	0.1	GO:0001672	regulation of chromatin assembly or disassembly(GO:0001672)
0.0	0.2	GO:0051775	response to redox state(GO:0051775)
0.0	0.0	GO:0006642	triglyceride mobilization(GO:0006642)
0.0	0.1	GO:0032494	response to peptidoglycan(GO:0032494)
0.0	0.1	GO:0034392	negative regulation of smooth muscle cell apoptotic process(GO:0034392)
0.0	0.1	GO:0042535	positive regulation of tumor necrosis factor biosynthetic process(GO:0042535)
0.0	0.1	GO:0032071	regulation of endodeoxyribonuclease activity(GO:0032071)
0.0	0.1	GO:0070266	necroptotic process(GO:0070266) programmed necrotic cell death(GO:0097300)
0.0	2.2	GO:0050852	T cell receptor signaling pathway(GO:0050852)
0.0	0.1	GO:0043268	positive regulation of potassium ion transport(GO:0043268)
0.0	0.4	GO:0045648	positive regulation of erythrocyte differentiation(GO:0045648)
0.0	0.1	GO:0048304	positive regulation of isotype switching to IgG isotypes(GO:0048304)
0.0	0.2	GO:0019695	choline metabolic process(GO:0019695)
0.0	0.1	GO:0071379	cellular response to prostaglandin stimulus(GO:0071379)
0.0	0.2	GO:0006269	DNA replication, synthesis of RNA primer(GO:0006269)
0.0	0.0	GO:0048631	regulation of skeletal muscle tissue growth(GO:0048631)
0.0	0.3	GO:0043124	negative regulation of I-kappaB kinase/NF-kappaB signaling(GO:0043124)
0.0	0.1	GO:0010989	negative regulation of low-density lipoprotein particle clearance(GO:0010989)
0.0	0.1	GO:0045943	positive regulation of transcription from RNA polymerase I promoter(GO:0045943)
0.0	0.1	GO:0046121	deoxyribonucleoside catabolic process(GO:0046121)
0.0	0.4	GO:0018107	peptidyl-threonine phosphorylation(GO:0018107)
0.0	0.2	GO:0007035	vacuolar acidification(GO:0007035)
0.0	0.3	GO:0043508	negative regulation of JUN kinase activity(GO:0043508)
0.0	0.3	GO:0006198	cAMP catabolic process(GO:0006198)
0.0	0.4	GO:0031146	SCF-dependent proteasomal ubiquitin-dependent protein catabolic process(GO:0031146)
0.0	0.2	GO:0051290	protein heterotetramerization(GO:0051290)
0.0	0.2	GO:0060292	long term synaptic depression(GO:0060292)
0.0	0.1	GO:0033262	regulation of nuclear cell cycle DNA replication(GO:0033262)
0.0	0.1	GO:0031282	regulation of guanylate cyclase activity(GO:0031282)
0.0	0.2	GO:0048069	eye pigmentation(GO:0048069)
0.0	0.1	GO:0018206	peptidyl-methionine modification(GO:0018206)
0.0	0.1	GO:0034121	regulation of toll-like receptor signaling pathway(GO:0034121)
0.0	0.1	GO:0007262	STAT protein import into nucleus(GO:0007262)
0.0	0.0	GO:0072161	mesenchymal cell differentiation involved in kidney development(GO:0072161) metanephric mesenchymal cell differentiation(GO:0072162) mesenchymal cell differentiation involved in renal system development(GO:2001012)
0.0	0.1	GO:0003010	voluntary skeletal muscle contraction(GO:0003010) twitch skeletal muscle contraction(GO:0014721)
0.0	0.2	GO:0045351	type I interferon biosynthetic process(GO:0045351)
0.0	0.1	GO:0090199	regulation of release of cytochrome c from mitochondria(GO:0090199) regulation of apoptotic signaling pathway(GO:2001233)
0.0	0.8	GO:0030835	negative regulation of actin filament depolymerization(GO:0030835)
0.0	0.1	GO:0035020	regulation of Rac protein signal transduction(GO:0035020)
0.0	0.3	GO:0045069	regulation of viral genome replication(GO:0045069)
0.0	0.1	GO:0035066	positive regulation of histone acetylation(GO:0035066) positive regulation of protein acetylation(GO:1901985) positive regulation of peptidyl-lysine acetylation(GO:2000758)
0.0	0.1	GO:0034379	very-low-density lipoprotein particle assembly(GO:0034379)
0.0	0.0	GO:0000281	mitotic cytokinesis(GO:0000281)
0.0	0.1	GO:0032715	negative regulation of interleukin-6 production(GO:0032715)
0.0	0.1	GO:0009822	alkaloid catabolic process(GO:0009822)
0.0	0.0	GO:0033089	positive regulation of T cell differentiation in thymus(GO:0033089) positive regulation of thymocyte aggregation(GO:2000400)
0.0	0.1	GO:0042983	amyloid precursor protein biosynthetic process(GO:0042983) regulation of amyloid precursor protein biosynthetic process(GO:0042984)
0.0	0.0	GO:0090023	positive regulation of neutrophil chemotaxis(GO:0090023) positive regulation of neutrophil migration(GO:1902624)
0.0	0.2	GO:0016601	Rac protein signal transduction(GO:0016601)
0.0	0.3	GO:0035437	protein retention in ER lumen(GO:0006621) maintenance of protein localization in endoplasmic reticulum(GO:0035437)
0.0	0.2	GO:0006546	glycine catabolic process(GO:0006546)
0.0	0.2	GO:0032367	intracellular sterol transport(GO:0032366) intracellular cholesterol transport(GO:0032367)
0.0	0.1	GO:0043951	negative regulation of cAMP-mediated signaling(GO:0043951)
0.0	0.1	GO:0014041	regulation of neuron maturation(GO:0014041) regulation of cell maturation(GO:1903429)
0.0	0.2	GO:0060023	soft palate development(GO:0060023)
0.0	0.3	GO:1901072	amino sugar catabolic process(GO:0046348) glucosamine-containing compound catabolic process(GO:1901072)
0.0	0.1	GO:0046884	follicle-stimulating hormone secretion(GO:0046884)
0.0	0.1	GO:0070493	thrombin receptor signaling pathway(GO:0070493)
0.0	0.1	GO:0006432	phenylalanyl-tRNA aminoacylation(GO:0006432)
0.0	0.1	GO:0035426	extracellular matrix-cell signaling(GO:0035426)
0.0	0.1	GO:0005981	regulation of glycogen catabolic process(GO:0005981)
0.0	0.4	GO:0042771	intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator(GO:0042771)
0.0	0.1	GO:0060136	embryonic process involved in female pregnancy(GO:0060136)
0.0	0.1	GO:0002923	regulation of humoral immune response mediated by circulating immunoglobulin(GO:0002923) positive regulation of humoral immune response mediated by circulating immunoglobulin(GO:0002925)
0.0	0.0	GO:0051088	PMA-inducible membrane protein ectodomain proteolysis(GO:0051088)
0.0	0.0	GO:0000154	rRNA modification(GO:0000154)
0.0	0.1	GO:0034243	positive regulation of transcription elongation from RNA polymerase II promoter(GO:0032968) regulation of transcription elongation from RNA polymerase II promoter(GO:0034243)
0.0	0.0	GO:0048520	positive regulation of behavior(GO:0048520)
0.0	0.1	GO:0031442	positive regulation of mRNA 3'-end processing(GO:0031442) positive regulation of mRNA processing(GO:0050685) positive regulation of mRNA metabolic process(GO:1903313)
0.0	0.1	GO:1901419	regulation of response to alcohol(GO:1901419)
0.0	0.1	GO:0001574	ganglioside biosynthetic process(GO:0001574)
0.0	0.0	GO:0009188	ADP biosynthetic process(GO:0006172) purine nucleoside diphosphate biosynthetic process(GO:0009136) purine ribonucleoside diphosphate biosynthetic process(GO:0009180) ribonucleoside diphosphate biosynthetic process(GO:0009188)
0.0	0.2	GO:0030890	positive regulation of B cell proliferation(GO:0030890)
0.0	0.4	GO:0046676	negative regulation of insulin secretion(GO:0046676)
0.0	0.1	GO:0006772	thiamine metabolic process(GO:0006772)
0.0	0.2	GO:0031122	cytoplasmic microtubule organization(GO:0031122)
0.0	0.2	GO:0046339	diacylglycerol metabolic process(GO:0046339)
0.0	0.1	GO:0046885	regulation of hormone biosynthetic process(GO:0046885)
0.0	0.0	GO:0052173	modulation by symbiont of host defense response(GO:0052031) response to defenses of other organism involved in symbiotic interaction(GO:0052173) response to host defenses(GO:0052200) modulation by organism of defense response of other organism involved in symbiotic interaction(GO:0052255) positive regulation by symbiont of host defense response(GO:0052509) positive regulation by organism of defense response of other organism involved in symbiotic interaction(GO:0052510) modulation by organism of immune response of other organism involved in symbiotic interaction(GO:0052552) modulation by symbiont of host immune response(GO:0052553) response to immune response of other organism involved in symbiotic interaction(GO:0052564) response to host immune response(GO:0052572) response to host(GO:0075136)
0.0	0.1	GO:0070682	proteasome regulatory particle assembly(GO:0070682)
0.0	0.1	GO:0060057	apoptotic process involved in mammary gland involution(GO:0060057) positive regulation of apoptotic process involved in mammary gland involution(GO:0060058) positive regulation of apoptotic process involved in morphogenesis(GO:1902339) regulation of mammary gland involution(GO:1903519) positive regulation of mammary gland involution(GO:1903521) positive regulation of apoptotic process involved in development(GO:1904747)
0.0	0.0	GO:0002281	macrophage activation involved in immune response(GO:0002281)
0.0	0.0	GO:0070934	CRD-mediated mRNA stabilization(GO:0070934)
0.0	0.1	GO:0044273	sulfur compound catabolic process(GO:0044273)
0.0	0.8	GO:0042059	negative regulation of epidermal growth factor receptor signaling pathway(GO:0042059) negative regulation of ERBB signaling pathway(GO:1901185)
0.0	0.4	GO:0046427	positive regulation of JAK-STAT cascade(GO:0046427) positive regulation of STAT cascade(GO:1904894)
0.0	0.0	GO:0034629	cellular protein complex localization(GO:0034629)
0.0	0.5	GO:1900181	negative regulation of protein import into nucleus(GO:0042308) negative regulation of protein localization to nucleus(GO:1900181) negative regulation of protein import(GO:1904590)
0.0	0.3	GO:0046579	positive regulation of Ras protein signal transduction(GO:0046579)
0.0	1.7	GO:0008360	regulation of cell shape(GO:0008360)
0.0	0.1	GO:0070172	positive regulation of tooth mineralization(GO:0070172)
0.0	0.2	GO:0018026	peptidyl-lysine monomethylation(GO:0018026)
0.0	0.0	GO:0070669	response to interleukin-2(GO:0070669)
0.0	0.0	GO:0060206	estrous cycle phase(GO:0060206)
0.0	0.1	GO:0055015	ventricular cardiac muscle cell development(GO:0055015)
0.0	0.2	GO:0034370	triglyceride-rich lipoprotein particle remodeling(GO:0034370) very-low-density lipoprotein particle remodeling(GO:0034372)
0.0	0.1	GO:0000389	mRNA 3'-splice site recognition(GO:0000389)
0.0	0.1	GO:0045723	positive regulation of fatty acid biosynthetic process(GO:0045723)
0.0	0.3	GO:0031581	hemidesmosome assembly(GO:0031581)
0.0	0.1	GO:0042518	negative regulation of tyrosine phosphorylation of Stat3 protein(GO:0042518)
0.0	0.2	GO:0050930	induction of positive chemotaxis(GO:0050930)
0.0	0.1	GO:0030187	melatonin metabolic process(GO:0030186) melatonin biosynthetic process(GO:0030187)
0.0	0.1	GO:0032922	circadian regulation of gene expression(GO:0032922)
0.0	0.1	GO:0016572	histone phosphorylation(GO:0016572)
0.0	0.1	GO:0006855	drug transmembrane transport(GO:0006855)
0.0	0.4	GO:0042776	mitochondrial ATP synthesis coupled proton transport(GO:0042776)
0.0	0.6	GO:0000289	nuclear-transcribed mRNA poly(A) tail shortening(GO:0000289)
0.0	0.1	GO:0009313	oligosaccharide catabolic process(GO:0009313)
0.0	0.2	GO:0007250	activation of NF-kappaB-inducing kinase activity(GO:0007250) NIK/NF-kappaB signaling(GO:0038061) regulation of NIK/NF-kappaB signaling(GO:1901222) positive regulation of NIK/NF-kappaB signaling(GO:1901224)
0.0	0.2	GO:0000303	response to superoxide(GO:0000303)
0.0	0.0	GO:0010831	positive regulation of myotube differentiation(GO:0010831)
0.0	0.4	GO:0016254	preassembly of GPI anchor in ER membrane(GO:0016254)
0.0	0.2	GO:0006983	ER overload response(GO:0006983)
0.0	0.1	GO:0019228	neuronal action potential(GO:0019228)
0.0	0.1	GO:0072531	pyrimidine-containing compound transmembrane transport(GO:0072531)
0.0	0.1	GO:0007021	tubulin complex assembly(GO:0007021)
0.0	0.1	GO:0061099	negative regulation of protein tyrosine kinase activity(GO:0061099)
0.0	0.1	GO:0045601	regulation of endothelial cell differentiation(GO:0045601)
0.0	0.0	GO:0090206	negative regulation of cholesterol biosynthetic process(GO:0045541) negative regulation of cholesterol metabolic process(GO:0090206)
0.0	0.3	GO:0001510	RNA methylation(GO:0001510)
0.0	0.1	GO:0009296	obsolete flagellum assembly(GO:0009296)
0.0	0.1	GO:0006379	mRNA cleavage(GO:0006379)
0.0	0.1	GO:0060712	spongiotrophoblast layer development(GO:0060712)
0.0	0.1	GO:0060662	tube lumen cavitation(GO:0060605) salivary gland cavitation(GO:0060662)
0.0	0.1	GO:0071816	protein insertion into ER membrane(GO:0045048) tail-anchored membrane protein insertion into ER membrane(GO:0071816)
0.0	0.0	GO:0006369	termination of RNA polymerase II transcription(GO:0006369)
0.0	0.2	GO:0016558	protein import into peroxisome matrix(GO:0016558)
0.0	0.2	GO:0050688	regulation of defense response to virus(GO:0050688)
0.0	0.1	GO:0015919	peroxisomal membrane transport(GO:0015919)
0.0	0.1	GO:0009133	nucleoside diphosphate biosynthetic process(GO:0009133)
0.0	0.0	GO:0043501	skeletal muscle adaptation(GO:0043501)
0.0	0.4	GO:2000117	negative regulation of cysteine-type endopeptidase activity(GO:2000117)
0.0	0.7	GO:0006888	ER to Golgi vesicle-mediated transport(GO:0006888)
0.0	0.1	GO:0032364	oxygen homeostasis(GO:0032364)
0.0	0.1	GO:0031115	negative regulation of microtubule polymerization(GO:0031115)
0.0	0.0	GO:0039694	single stranded viral RNA replication via double stranded DNA intermediate(GO:0039692) viral RNA genome replication(GO:0039694) RNA replication(GO:0039703)
0.0	0.1	GO:0035095	behavioral response to nicotine(GO:0035095)
0.0	0.0	GO:0034088	maintenance of sister chromatid cohesion(GO:0034086) maintenance of mitotic sister chromatid cohesion(GO:0034088)
0.0	0.1	GO:0060088	auditory receptor cell morphogenesis(GO:0002093) auditory receptor cell stereocilium organization(GO:0060088)
0.0	0.0	GO:0090224	regulation of spindle organization(GO:0090224)
0.0	0.0	GO:0045618	positive regulation of keratinocyte differentiation(GO:0045618)
0.0	0.1	GO:0006530	asparagine catabolic process(GO:0006530) asparagine catabolic process via L-aspartate(GO:0033345)
0.0	0.2	GO:0006704	glucocorticoid biosynthetic process(GO:0006704)
0.0	0.1	GO:0021854	hypothalamus development(GO:0021854)
0.0	0.0	GO:0044650	virion attachment to host cell(GO:0019062) adhesion of symbiont to host cell(GO:0044650) peptide antigen transport(GO:0046968)
0.0	0.0	GO:0006089	lactate metabolic process(GO:0006089)
0.0	0.1	GO:0050847	progesterone receptor signaling pathway(GO:0050847)
0.0	0.1	GO:0048670	regulation of collateral sprouting(GO:0048670)
0.0	0.9	GO:0006968	cellular defense response(GO:0006968)
0.0	0.2	GO:0046784	viral mRNA export from host cell nucleus(GO:0046784)
0.0	0.1	GO:0000239	pachytene(GO:0000239)
0.0	0.0	GO:0032925	regulation of activin receptor signaling pathway(GO:0032925)
0.0	1.1	GO:0071427	mRNA export from nucleus(GO:0006406) mRNA-containing ribonucleoprotein complex export from nucleus(GO:0071427)
0.0	0.1	GO:0007029	endoplasmic reticulum organization(GO:0007029)
0.0	0.2	GO:0006378	mRNA polyadenylation(GO:0006378)
0.0	0.1	GO:0006422	aspartyl-tRNA aminoacylation(GO:0006422)
0.0	0.0	GO:0060972	left/right pattern formation(GO:0060972)
0.0	0.1	GO:0032703	negative regulation of interleukin-2 production(GO:0032703)
0.0	0.1	GO:0006420	arginyl-tRNA aminoacylation(GO:0006420)
0.0	0.1	GO:0045945	positive regulation of transcription from RNA polymerase III promoter(GO:0045945)
0.0	0.1	GO:0042447	hormone catabolic process(GO:0042447)
0.0	0.1	GO:0033522	histone H2A ubiquitination(GO:0033522)
0.0	0.1	GO:0031641	regulation of myelination(GO:0031641)
0.0	0.1	GO:0006614	SRP-dependent cotranslational protein targeting to membrane(GO:0006614)
0.0	0.1	GO:0033687	osteoblast proliferation(GO:0033687)
0.0	0.0	GO:0002125	maternal aggressive behavior(GO:0002125)
0.0	0.2	GO:0000050	urea cycle(GO:0000050)
0.0	0.1	GO:0031507	heterochromatin assembly(GO:0031507) heterochromatin organization(GO:0070828)
0.0	0.1	GO:0008625	extrinsic apoptotic signaling pathway via death domain receptors(GO:0008625) extrinsic apoptotic signaling pathway(GO:0097191)
0.0	0.0	GO:0034695	response to prostaglandin E(GO:0034695)
0.0	0.2	GO:1904031	positive regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045737) positive regulation of cyclin-dependent protein kinase activity(GO:1904031)
0.0	0.1	GO:0031293	membrane protein intracellular domain proteolysis(GO:0031293)
0.0	0.1	GO:0048617	embryonic foregut morphogenesis(GO:0048617)
0.0	0.2	GO:0048873	homeostasis of number of cells within a tissue(GO:0048873)
0.0	0.1	GO:0046688	response to copper ion(GO:0046688)
0.0	0.1	GO:0019255	glucose 1-phosphate metabolic process(GO:0019255)
0.0	0.5	GO:0000387	spliceosomal snRNP assembly(GO:0000387)
0.0	0.3	GO:0008633	obsolete activation of pro-apoptotic gene products(GO:0008633)
0.0	0.0	GO:0016199	axon midline choice point recognition(GO:0016199)
0.0	0.0	GO:0051123	RNA polymerase II transcriptional preinitiation complex assembly(GO:0051123) DNA-templated transcriptional preinitiation complex assembly(GO:0070897)
0.0	0.2	GO:0043968	histone H2A acetylation(GO:0043968)
0.0	0.0	GO:0000733	DNA strand renaturation(GO:0000733)
0.0	0.3	GO:0000045	autophagosome assembly(GO:0000045) autophagosome organization(GO:1905037)
0.0	0.1	GO:0006013	mannose metabolic process(GO:0006013)
0.0	0.2	GO:0043242	negative regulation of protein complex disassembly(GO:0043242) negative regulation of protein depolymerization(GO:1901880)
0.0	0.0	GO:0022030	cerebral cortex radial glia guided migration(GO:0021801) layer formation in cerebral cortex(GO:0021819) telencephalon glial cell migration(GO:0022030)
0.0	0.1	GO:0016236	macroautophagy(GO:0016236)
0.0	0.1	GO:0006122	mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122)
0.0	0.1	GO:0008218	bioluminescence(GO:0008218)
0.0	0.1	GO:0001662	behavioral fear response(GO:0001662)
0.0	0.0	GO:0010759	positive regulation of macrophage chemotaxis(GO:0010759)
0.0	0.1	GO:0031648	protein destabilization(GO:0031648)
0.0	0.0	GO:0014888	striated muscle adaptation(GO:0014888)
0.0	0.1	GO:0072170	metanephric tubule development(GO:0072170) metanephric epithelium development(GO:0072207)
0.0	0.1	GO:0043967	histone H4 acetylation(GO:0043967)
0.0	0.0	GO:0032747	positive regulation of interleukin-23 production(GO:0032747)
0.0	0.1	GO:0051965	positive regulation of synapse assembly(GO:0051965)
0.0	0.0	GO:0046877	regulation of saliva secretion(GO:0046877)
0.0	0.0	GO:0051451	myoblast migration(GO:0051451)
0.0	0.1	GO:0015893	drug transport(GO:0015893)
0.0	0.0	GO:0045875	negative regulation of sister chromatid cohesion(GO:0045875)
0.0	0.1	GO:0006658	phosphatidylserine metabolic process(GO:0006658)
0.0	0.1	GO:0006991	response to sterol depletion(GO:0006991)
0.0	0.1	GO:0045007	depurination(GO:0045007)
0.0	0.1	GO:0006391	transcription initiation from mitochondrial promoter(GO:0006391)
0.0	0.0	GO:0031297	replication fork processing(GO:0031297)
0.0	0.1	GO:0006999	nuclear pore organization(GO:0006999)
0.0	0.0	GO:0042516	regulation of tyrosine phosphorylation of Stat3 protein(GO:0042516)
0.0	0.0	GO:0006047	UDP-N-acetylglucosamine metabolic process(GO:0006047)
0.0	0.1	GO:0046513	ceramide biosynthetic process(GO:0046513)
0.0	0.2	GO:0006268	DNA unwinding involved in DNA replication(GO:0006268)
0.0	0.0	GO:0002704	negative regulation of leukocyte mediated immunity(GO:0002704)
0.0	0.0	GO:0007063	regulation of sister chromatid cohesion(GO:0007063)
0.0	0.1	GO:0046149	porphyrin-containing compound catabolic process(GO:0006787) tetrapyrrole catabolic process(GO:0033015) heme catabolic process(GO:0042167) pigment catabolic process(GO:0046149)
0.0	0.1	GO:0018410	C-terminal protein amino acid modification(GO:0018410)
0.0	0.1	GO:0045187	regulation of circadian sleep/wake cycle(GO:0042749) regulation of circadian sleep/wake cycle, sleep(GO:0045187)
0.0	0.1	GO:0018343	protein farnesylation(GO:0018343)
0.0	0.0	GO:2000008	regulation of protein localization to cell surface(GO:2000008)
0.0	0.1	GO:0006685	sphingomyelin catabolic process(GO:0006685)
0.0	0.0	GO:0006105	succinate metabolic process(GO:0006105)
0.0	0.0	GO:0046321	positive regulation of fatty acid oxidation(GO:0046321)
0.0	0.0	GO:0042534	tumor necrosis factor biosynthetic process(GO:0042533) regulation of tumor necrosis factor biosynthetic process(GO:0042534)
0.0	0.0	GO:0000019	regulation of mitotic recombination(GO:0000019)
0.0	0.1	GO:0046655	folic acid metabolic process(GO:0046655)
0.0	0.1	GO:0070059	intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress(GO:0070059)
0.0	0.4	GO:0021549	cerebellum development(GO:0021549)
0.0	0.1	GO:0009253	peptidoglycan metabolic process(GO:0000270) peptidoglycan catabolic process(GO:0009253)
0.0	0.1	GO:0030259	lipid glycosylation(GO:0030259)
0.0	0.1	GO:0043249	erythrocyte maturation(GO:0043249)
0.0	0.1	GO:0006544	glycine metabolic process(GO:0006544)
0.0	0.1	GO:0000301	retrograde transport, vesicle recycling within Golgi(GO:0000301)
0.0	0.0	GO:0071372	cellular response to follicle-stimulating hormone stimulus(GO:0071372)
0.0	0.2	GO:0031280	negative regulation of adenylate cyclase activity(GO:0007194) negative regulation of cyclase activity(GO:0031280) negative regulation of lyase activity(GO:0051350)
0.0	0.1	GO:0006285	base-excision repair, AP site formation(GO:0006285)
0.0	0.0	GO:0034421	post-translational protein acetylation(GO:0034421)
0.0	0.1	GO:0031163	iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163)
0.0	0.0	GO:0009214	cyclic nucleotide catabolic process(GO:0009214)
0.0	0.3	GO:0032012	regulation of ARF protein signal transduction(GO:0032012)
0.0	0.1	GO:0001832	blastocyst growth(GO:0001832)
0.0	0.0	GO:0042435	indole-containing compound biosynthetic process(GO:0042435)
0.0	0.1	GO:0031033	myosin filament organization(GO:0031033)
0.0	0.0	GO:0022417	protein maturation by protein folding(GO:0022417)
0.0	0.0	GO:0040009	regulation of growth rate(GO:0040009)
0.0	0.0	GO:0000089	mitotic metaphase(GO:0000089)
0.0	0.2	GO:0033540	fatty acid beta-oxidation using acyl-CoA oxidase(GO:0033540)
0.0	0.2	GO:0007190	activation of adenylate cyclase activity(GO:0007190)
0.0	0.1	GO:0045948	positive regulation of translational initiation(GO:0045948)
0.0	0.2	GO:0006004	fucose metabolic process(GO:0006004)
0.0	0.3	GO:0009083	branched-chain amino acid catabolic process(GO:0009083)
0.0	0.1	GO:0005513	detection of calcium ion(GO:0005513)
0.0	0.0	GO:0031268	pseudopodium organization(GO:0031268)
0.0	0.2	GO:0000245	spliceosomal complex assembly(GO:0000245)
0.0	0.1	GO:0015693	magnesium ion transport(GO:0015693)
0.0	0.0	GO:0043631	RNA polyadenylation(GO:0043631)
0.0	0.1	GO:0051788	response to misfolded protein(GO:0051788)
0.0	0.0	GO:0070102	interleukin-6-mediated signaling pathway(GO:0070102)
0.0	0.0	GO:0001916	positive regulation of T cell mediated cytotoxicity(GO:0001916)
0.0	0.1	GO:0035235	ionotropic glutamate receptor signaling pathway(GO:0035235)
0.0	0.1	GO:0051131	chaperone-mediated protein complex assembly(GO:0051131)
0.0	0.0	GO:0046502	uroporphyrinogen III metabolic process(GO:0046502)
0.0	0.1	GO:0008354	germ cell migration(GO:0008354)
0.0	0.1	GO:0006449	regulation of translational termination(GO:0006449)
0.0	0.1	GO:0070389	chaperone cofactor-dependent protein refolding(GO:0070389)
0.0	0.0	GO:0043568	positive regulation of insulin-like growth factor receptor signaling pathway(GO:0043568)
0.0	0.0	GO:0060396	growth hormone receptor signaling pathway(GO:0060396) cellular response to growth hormone stimulus(GO:0071378)
0.0	0.0	GO:0098870	neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870)
0.0	0.1	GO:0006020	inositol metabolic process(GO:0006020)
0.0	0.0	GO:2000144	positive regulation of transcription initiation from RNA polymerase II promoter(GO:0060261) positive regulation of DNA-templated transcription, initiation(GO:2000144)
0.0	0.0	GO:0000463	maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000463) maturation of LSU-rRNA(GO:0000470)
0.0	0.0	GO:0045989	positive regulation of striated muscle contraction(GO:0045989)
0.0	0.0	GO:1901890	positive regulation of focal adhesion assembly(GO:0051894) positive regulation of cell junction assembly(GO:1901890) positive regulation of adherens junction organization(GO:1903393)
0.0	0.1	GO:0007089	traversing start control point of mitotic cell cycle(GO:0007089) positive regulation of G1/S transition of mitotic cell cycle(GO:1900087) positive regulation of cell cycle G1/S phase transition(GO:1902808)
0.0	0.0	GO:0043931	ossification involved in bone maturation(GO:0043931)
0.0	1.1	GO:0022904	respiratory electron transport chain(GO:0022904)
0.0	0.0	GO:0071166	ribonucleoprotein complex localization(GO:0071166)
0.0	0.0	GO:0032000	positive regulation of fatty acid beta-oxidation(GO:0032000)
0.0	0.6	GO:0050434	positive regulation of viral transcription(GO:0050434)
0.0	0.0	GO:0007144	female meiosis I(GO:0007144)
0.0	0.1	GO:0043666	regulation of phosphoprotein phosphatase activity(GO:0043666)
0.0	0.0	GO:0045110	intermediate filament bundle assembly(GO:0045110)
0.0	3.0	GO:0006397	mRNA processing(GO:0006397)
0.0	0.0	GO:0051657	maintenance of organelle location(GO:0051657)
0.0	0.0	GO:0040020	regulation of meiotic nuclear division(GO:0040020)
0.0	0.1	GO:0045744	negative regulation of G-protein coupled receptor protein signaling pathway(GO:0045744)
0.0	0.1	GO:0051926	negative regulation of calcium ion transport(GO:0051926)
0.0	0.3	GO:0007051	spindle organization(GO:0007051)
0.0	0.1	GO:0021781	glial cell fate commitment(GO:0021781)
0.0	0.1	GO:0046501	protoporphyrinogen IX metabolic process(GO:0046501)
0.0	0.0	GO:0001302	replicative cell aging(GO:0001302)
0.0	0.2	GO:0050832	defense response to fungus(GO:0050832)
0.0	0.1	GO:0006003	fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.0	0.1	GO:0008291	acetylcholine metabolic process(GO:0008291) acetate ester metabolic process(GO:1900619)
0.0	0.1	GO:0034314	Arp2/3 complex-mediated actin nucleation(GO:0034314)
0.0	0.4	GO:0060333	interferon-gamma-mediated signaling pathway(GO:0060333)
0.0	0.1	GO:0007020	microtubule nucleation(GO:0007020)
0.0	0.1	GO:0000291	nuclear-transcribed mRNA catabolic process, exonucleolytic(GO:0000291) exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay(GO:0043928)
0.0	0.0	GO:0010623	programmed cell death involved in cell development(GO:0010623) regulation of retinal cell programmed cell death(GO:0046668)
0.0	0.0	GO:0042178	xenobiotic catabolic process(GO:0042178)
0.0	0.1	GO:0000085	mitotic G2 phase(GO:0000085) G2 phase(GO:0051319)
0.0	0.0	GO:0032392	DNA geometric change(GO:0032392)
0.0	0.0	GO:0031573	intra-S DNA damage checkpoint(GO:0031573)
0.0	0.2	GO:0030317	sperm motility(GO:0030317)
0.0	0.2	GO:0000083	regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083)
0.0	0.0	GO:0051573	negative regulation of histone H3-K9 methylation(GO:0051573)
0.0	0.0	GO:0042940	D-amino acid transport(GO:0042940)
0.0	0.0	GO:0001921	positive regulation of receptor recycling(GO:0001921)
0.0	0.0	GO:0018344	protein geranylgeranylation(GO:0018344)
0.0	0.1	GO:0007271	synaptic transmission, cholinergic(GO:0007271)
0.0	0.1	GO:0048532	anatomical structure arrangement(GO:0048532)
0.0	0.0	GO:0015781	pyrimidine nucleotide-sugar transport(GO:0015781)
0.0	0.0	GO:0032543	mitochondrial translation(GO:0032543)
0.0	0.0	GO:0007638	mechanosensory behavior(GO:0007638)
0.0	0.1	GO:0007217	tachykinin receptor signaling pathway(GO:0007217)
0.0	0.1	GO:0048496	maintenance of organ identity(GO:0048496)
0.0	0.1	GO:0098930	axonal transport(GO:0098930)
0.0	0.1	GO:1901661	quinone metabolic process(GO:1901661)
0.0	0.1	GO:0006783	heme biosynthetic process(GO:0006783)
0.0	0.1	GO:0032784	regulation of DNA-templated transcription, elongation(GO:0032784)
0.0	0.1	GO:0043558	regulation of translational initiation in response to stress(GO:0043558)
0.0	0.1	GO:0001514	selenocysteine incorporation(GO:0001514) translational readthrough(GO:0006451)
0.0	0.0	GO:0046543	development of secondary female sexual characteristics(GO:0046543)
0.0	0.0	GO:0042921	corticosteroid receptor signaling pathway(GO:0031958) glucocorticoid receptor signaling pathway(GO:0042921)
0.0	0.0	GO:0034653	diterpenoid catabolic process(GO:0016103) terpenoid catabolic process(GO:0016115) retinoic acid catabolic process(GO:0034653)
0.0	0.1	GO:0015840	urea transport(GO:0015840)
0.0	0.0	GO:0045979	positive regulation of nucleotide catabolic process(GO:0030813) positive regulation of glycolytic process(GO:0045821) positive regulation of nucleoside metabolic process(GO:0045979) positive regulation of cofactor metabolic process(GO:0051194) positive regulation of coenzyme metabolic process(GO:0051197) positive regulation of ATP metabolic process(GO:1903580)
0.0	0.1	GO:0098534	centriole replication(GO:0007099) centriole assembly(GO:0098534)
0.0	0.0	GO:0010890	positive regulation of sequestering of triglyceride(GO:0010890)
0.0	0.1	GO:0071044	histone mRNA catabolic process(GO:0071044)
0.0	0.0	GO:0002068	glandular epithelial cell development(GO:0002068)
0.0	0.1	GO:0051607	defense response to virus(GO:0051607)
0.0	0.0	GO:0070672	response to interleukin-15(GO:0070672)
0.0	0.1	GO:0007032	endosome organization(GO:0007032)
0.0	0.0	GO:0007097	nuclear migration(GO:0007097)
0.0	0.1	GO:0006012	galactose metabolic process(GO:0006012)
0.0	0.0	GO:0045654	positive regulation of megakaryocyte differentiation(GO:0045654) positive regulation of hematopoietic progenitor cell differentiation(GO:1901534)
0.0	0.0	GO:0014044	Schwann cell development(GO:0014044)
0.0	0.0	GO:0007341	penetration of zona pellucida(GO:0007341)
0.0	0.4	GO:0035966	response to topologically incorrect protein(GO:0035966)
0.0	0.0	GO:0031943	regulation of glucocorticoid metabolic process(GO:0031943)
0.0	0.2	GO:0001539	cilium or flagellum-dependent cell motility(GO:0001539)
0.0	0.3	GO:0050772	positive regulation of axonogenesis(GO:0050772)
0.0	0.4	GO:0051084	'de novo' posttranslational protein folding(GO:0051084)
0.0	0.0	GO:1901970	positive regulation of mitotic metaphase/anaphase transition(GO:0045842) positive regulation of mitotic sister chromatid separation(GO:1901970) positive regulation of metaphase/anaphase transition of cell cycle(GO:1902101)
0.0	0.1	GO:0006506	GPI anchor biosynthetic process(GO:0006506)
0.0	0.0	GO:0045672	positive regulation of osteoclast differentiation(GO:0045672)
0.0	0.0	GO:0048387	negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.0	0.0	GO:0032527	protein exit from endoplasmic reticulum(GO:0032527)
0.0	0.1	GO:1902591	vesicle coating(GO:0006901) single-organism membrane budding(GO:1902591)
0.0	0.0	GO:0015015	heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.0	0.1	GO:0019933	cAMP-mediated signaling(GO:0019933)
0.0	0.0	GO:0071569	protein ufmylation(GO:0071569)
0.0	0.1	GO:0046849	bone remodeling(GO:0046849)
0.0	0.8	GO:0006364	rRNA processing(GO:0006364)
0.0	0.0	GO:0043045	DNA methylation involved in embryo development(GO:0043045) changes to DNA methylation involved in embryo development(GO:1901538)
0.0	0.3	GO:0042254	ribosome biogenesis(GO:0042254)
0.0	0.0	GO:0044818	mitotic G2/M transition checkpoint(GO:0044818)
0.0	0.1	GO:0001867	complement activation, lectin pathway(GO:0001867)
0.0	0.1	GO:0043101	purine-containing compound salvage(GO:0043101)
0.0	0.2	GO:0006904	vesicle docking involved in exocytosis(GO:0006904)
0.0	0.6	GO:0018279	peptidyl-asparagine modification(GO:0018196) protein N-linked glycosylation via asparagine(GO:0018279)
0.0	0.0	GO:0010288	response to lead ion(GO:0010288)
0.0	0.1	GO:0008156	negative regulation of DNA replication(GO:0008156)
0.0	0.1	GO:0007141	male meiosis I(GO:0007141)
0.0	0.1	GO:0006069	ethanol metabolic process(GO:0006067) ethanol oxidation(GO:0006069)
0.0	0.1	GO:0016180	snRNA processing(GO:0016180)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	1.9	GO:0001891	phagocytic cup(GO:0001891)
0.1	0.4	GO:0042105	alpha-beta T cell receptor complex(GO:0042105)
0.1	0.4	GO:0000506	glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.1	1.5	GO:0010494	cytoplasmic stress granule(GO:0010494)
0.1	0.4	GO:0070022	transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.1	0.4	GO:0032444	activin responsive factor complex(GO:0032444)
0.1	0.5	GO:0034993	microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.1	0.3	GO:0048179	activin receptor complex(GO:0048179)
0.1	0.7	GO:0008290	F-actin capping protein complex(GO:0008290)
0.1	0.5	GO:0070695	FHF complex(GO:0070695)
0.1	0.3	GO:0000942	condensed nuclear chromosome outer kinetochore(GO:0000942)
0.1	0.5	GO:0031264	death-inducing signaling complex(GO:0031264)
0.1	0.3	GO:0071664	catenin-TCF7L2 complex(GO:0071664)
0.1	0.5	GO:0042827	platelet dense granule(GO:0042827)
0.1	0.4	GO:0034045	pre-autophagosomal structure membrane(GO:0034045)
0.1	0.4	GO:0005658	alpha DNA polymerase:primase complex(GO:0005658)
0.1	0.8	GO:0005942	phosphatidylinositol 3-kinase complex(GO:0005942)
0.1	0.3	GO:0030870	Mre11 complex(GO:0030870)
0.1	0.1	GO:0032449	CBM complex(GO:0032449)
0.1	0.2	GO:0014731	spectrin-associated cytoskeleton(GO:0014731)
0.1	0.5	GO:0032040	small-subunit processome(GO:0032040)
0.1	0.2	GO:0035189	Rb-E2F complex(GO:0035189)
0.1	0.1	GO:0071564	npBAF complex(GO:0071564)
0.1	0.2	GO:0001740	Barr body(GO:0001740)
0.1	0.2	GO:0031235	intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.1	0.4	GO:0070688	MLL5-L complex(GO:0070688)
0.1	0.2	GO:0000137	Golgi cis cisterna(GO:0000137)
0.1	0.2	GO:0005850	eukaryotic translation initiation factor 2 complex(GO:0005850)
0.1	0.4	GO:0048786	presynaptic active zone(GO:0048786)
0.1	0.2	GO:0000124	SAGA complex(GO:0000124)
0.1	0.1	GO:0016442	RISC complex(GO:0016442) RNAi effector complex(GO:0031332)
0.1	0.3	GO:0030062	mitochondrial tricarboxylic acid cycle enzyme complex(GO:0030062)
0.1	0.1	GO:0005797	Golgi medial cisterna(GO:0005797)
0.0	0.1	GO:0072357	PTW/PP1 phosphatase complex(GO:0072357)
0.0	0.1	GO:1903561	extracellular exosome(GO:0070062) extracellular vesicle(GO:1903561)
0.0	0.1	GO:1990316	ATG1/ULK1 kinase complex(GO:1990316)
0.0	0.2	GO:0005954	calcium- and calmodulin-dependent protein kinase complex(GO:0005954)
0.0	0.2	GO:0070775	H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.0	0.1	GO:0005900	oncostatin-M receptor complex(GO:0005900)
0.0	0.2	GO:0032279	asymmetric synapse(GO:0032279) neuron to neuron synapse(GO:0098984)
0.0	0.2	GO:0071547	piP-body(GO:0071547)
0.0	1.7	GO:0005876	spindle microtubule(GO:0005876)
0.0	0.5	GO:0001772	immunological synapse(GO:0001772)
0.0	0.1	GO:0031092	platelet alpha granule membrane(GO:0031092)
0.0	0.1	GO:0031932	TORC2 complex(GO:0031932)
0.0	0.2	GO:0016593	Cdc73/Paf1 complex(GO:0016593)
0.0	0.4	GO:0000109	nucleotide-excision repair complex(GO:0000109)
0.0	0.3	GO:0000276	mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.0	0.1	GO:0005638	lamin filament(GO:0005638)
0.0	0.1	GO:0044224	juxtaparanode region of axon(GO:0044224)
0.0	0.2	GO:0005766	primary lysosome(GO:0005766) azurophil granule(GO:0042582)
0.0	0.3	GO:0005655	nucleolar ribonuclease P complex(GO:0005655) ribonuclease P complex(GO:0030677) multimeric ribonuclease P complex(GO:0030681)
0.0	0.2	GO:0017071	intracellular cyclic nucleotide activated cation channel complex(GO:0017071)
0.0	1.4	GO:0030175	filopodium(GO:0030175)
0.0	0.3	GO:0030127	COPII vesicle coat(GO:0030127)
0.0	0.1	GO:0030891	VCB complex(GO:0030891)
0.0	0.5	GO:0005852	eukaryotic translation initiation factor 3 complex(GO:0005852)
0.0	0.1	GO:0000164	protein phosphatase type 1 complex(GO:0000164)
0.0	0.4	GO:0005849	mRNA cleavage factor complex(GO:0005849)
0.0	0.4	GO:0035631	CD40 receptor complex(GO:0035631)
0.0	0.2	GO:0005869	dynactin complex(GO:0005869)
0.0	0.2	GO:0000242	pericentriolar material(GO:0000242)
0.0	0.5	GO:0008023	transcription elongation factor complex(GO:0008023)
0.0	0.1	GO:0032133	chromosome passenger complex(GO:0032133)
0.0	0.3	GO:0016471	vacuolar proton-transporting V-type ATPase complex(GO:0016471)
0.0	0.5	GO:0045334	clathrin-coated endocytic vesicle(GO:0045334)
0.0	0.2	GO:0000275	mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275)
0.0	0.1	GO:0031371	ubiquitin conjugating enzyme complex(GO:0031371)
0.0	0.0	GO:0005896	interleukin-6 receptor complex(GO:0005896)
0.0	0.1	GO:0072669	tRNA-splicing ligase complex(GO:0072669)
0.0	0.4	GO:0031105	septin complex(GO:0031105) septin cytoskeleton(GO:0032156)
0.0	1.0	GO:0042645	mitochondrial nucleoid(GO:0042645)
0.0	0.1	GO:0002080	acrosomal membrane(GO:0002080)
0.0	0.1	GO:0031082	BLOC complex(GO:0031082) BLOC-1 complex(GO:0031083)
0.0	0.1	GO:0001652	granular component(GO:0001652)
0.0	0.1	GO:0000153	cytoplasmic ubiquitin ligase complex(GO:0000153)
0.0	0.3	GO:0042101	T cell receptor complex(GO:0042101)
0.0	0.2	GO:0005662	DNA replication factor A complex(GO:0005662)
0.0	0.7	GO:0019005	SCF ubiquitin ligase complex(GO:0019005)
0.0	0.1	GO:0071986	Ragulator complex(GO:0071986)
0.0	0.1	GO:0016533	cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533)
0.0	0.1	GO:0035267	NuA4 histone acetyltransferase complex(GO:0035267)
0.0	0.1	GO:0030008	TRAPP complex(GO:0030008)
0.0	0.1	GO:0044462	external encapsulating structure part(GO:0044462)
0.0	0.0	GO:0030312	external encapsulating structure(GO:0030312)
0.0	0.1	GO:0000347	THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.0	0.1	GO:0005639	integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229) nuclear membrane part(GO:0044453)
0.0	0.3	GO:0005952	cAMP-dependent protein kinase complex(GO:0005952)
0.0	0.1	GO:0071204	histone pre-mRNA 3'end processing complex(GO:0071204)
0.0	0.2	GO:0031463	Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0	0.3	GO:0008250	oligosaccharyltransferase complex(GO:0008250)
0.0	0.4	GO:0031672	A band(GO:0031672)
0.0	0.2	GO:0030877	beta-catenin destruction complex(GO:0030877)
0.0	0.2	GO:0005890	sodium:potassium-exchanging ATPase complex(GO:0005890)
0.0	0.1	GO:0090533	cation-transporting ATPase complex(GO:0090533)
0.0	0.1	GO:0042598	obsolete vesicular fraction(GO:0042598)
0.0	0.2	GO:0005786	signal recognition particle, endoplasmic reticulum targeting(GO:0005786) signal recognition particle(GO:0048500)
0.0	0.2	GO:0000791	euchromatin(GO:0000791)
0.0	0.3	GO:0032039	integrator complex(GO:0032039)
0.0	0.1	GO:0051233	spindle midzone(GO:0051233)
0.0	0.1	GO:0005862	muscle thin filament tropomyosin(GO:0005862)
0.0	0.1	GO:0031464	Cul4A-RING E3 ubiquitin ligase complex(GO:0031464)
0.0	0.2	GO:0000782	telomere cap complex(GO:0000782) nuclear telomere cap complex(GO:0000783)
0.0	0.1	GO:0032009	early phagosome(GO:0032009)
0.0	0.2	GO:0098533	ATPase dependent transmembrane transport complex(GO:0098533) ATPase complex(GO:1904949)
0.0	1.5	GO:0032580	Golgi cisterna membrane(GO:0032580)
0.0	0.1	GO:0005750	mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
0.0	0.9	GO:0005905	clathrin-coated pit(GO:0005905)
0.0	1.1	GO:0055037	recycling endosome(GO:0055037)
0.0	0.3	GO:0016514	SWI/SNF complex(GO:0016514)
0.0	0.1	GO:0005883	neurofilament(GO:0005883)
0.0	0.1	GO:0030686	90S preribosome(GO:0030686)
0.0	0.1	GO:0001739	sex chromatin(GO:0001739)
0.0	0.3	GO:0098636	integrin complex(GO:0008305) protein complex involved in cell adhesion(GO:0098636)
0.0	0.4	GO:0005637	nuclear inner membrane(GO:0005637)
0.0	0.1	GO:0042629	mast cell granule(GO:0042629)
0.0	0.2	GO:0031010	ISWI-type complex(GO:0031010)
0.0	0.5	GO:0034364	high-density lipoprotein particle(GO:0034364)
0.0	0.2	GO:0045120	pronucleus(GO:0045120)
0.0	0.5	GO:0071339	MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339)
0.0	0.1	GO:0042583	chromaffin granule(GO:0042583) chromaffin granule membrane(GO:0042584)
0.0	0.4	GO:0000932	cytoplasmic mRNA processing body(GO:0000932)
0.0	0.5	GO:0005689	U12-type spliceosomal complex(GO:0005689)
0.0	0.0	GO:0071817	MMXD complex(GO:0071817)
0.0	0.1	GO:0034673	inhibin-betaglycan-ActRII complex(GO:0034673)
0.0	0.2	GO:0016272	prefoldin complex(GO:0016272)
0.0	1.1	GO:0034399	nuclear periphery(GO:0034399)
0.0	0.1	GO:0008540	proteasome regulatory particle, base subcomplex(GO:0008540)
0.0	0.1	GO:0042825	TAP complex(GO:0042825)
0.0	0.0	GO:0043625	delta DNA polymerase complex(GO:0043625)
0.0	1.5	GO:0048770	melanosome(GO:0042470) pigment granule(GO:0048770)
0.0	0.8	GO:0000794	condensed nuclear chromosome(GO:0000794)
0.0	0.1	GO:0033179	proton-transporting V-type ATPase, V0 domain(GO:0033179)
0.0	0.2	GO:0043020	NADPH oxidase complex(GO:0043020)
0.0	0.0	GO:0032809	neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.0	0.1	GO:0000300	obsolete peripheral to membrane of membrane fraction(GO:0000300)
0.0	0.1	GO:0042765	GPI-anchor transamidase complex(GO:0042765)
0.0	0.1	GO:0071818	BAT3 complex(GO:0071818) ER membrane insertion complex(GO:0072379)
0.0	0.1	GO:0016602	CCAAT-binding factor complex(GO:0016602)
0.0	0.3	GO:0000159	protein phosphatase type 2A complex(GO:0000159)
0.0	0.1	GO:0030895	apolipoprotein B mRNA editing enzyme complex(GO:0030895)
0.0	2.1	GO:0009897	external side of plasma membrane(GO:0009897)
0.0	0.2	GO:0005732	small nucleolar ribonucleoprotein complex(GO:0005732)
0.0	0.1	GO:0030125	clathrin vesicle coat(GO:0030125) clathrin coat of trans-Golgi network vesicle(GO:0030130)
0.0	0.1	GO:0034451	centriolar satellite(GO:0034451)
0.0	0.1	GO:0033011	perinuclear theca(GO:0033011)
0.0	0.2	GO:0046658	anchored component of plasma membrane(GO:0046658)
0.0	0.5	GO:0016592	mediator complex(GO:0016592)
0.0	0.2	GO:0005892	acetylcholine-gated channel complex(GO:0005892)
0.0	0.2	GO:0043209	myelin sheath(GO:0043209)
0.0	0.6	GO:0015030	Cajal body(GO:0015030)
0.0	1.4	GO:0008076	voltage-gated potassium channel complex(GO:0008076)
0.0	0.3	GO:0031201	SNARE complex(GO:0031201)
0.0	0.0	GO:0005641	nuclear envelope lumen(GO:0005641)
0.0	0.1	GO:0000796	condensin complex(GO:0000796)
0.0	0.1	GO:0031616	spindle pole centrosome(GO:0031616)
0.0	0.1	GO:0000444	MIS12/MIND type complex(GO:0000444)
0.0	0.0	GO:0005697	telomerase holoenzyme complex(GO:0005697)
0.0	0.2	GO:0032391	photoreceptor connecting cilium(GO:0032391)
0.0	0.0	GO:0061200	clathrin-sculpted gamma-aminobutyric acid transport vesicle(GO:0061200) clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane(GO:0061202)
0.0	1.3	GO:0019717	obsolete synaptosome(GO:0019717)
0.0	0.1	GO:0031080	nuclear pore outer ring(GO:0031080)
0.0	0.1	GO:0005838	proteasome regulatory particle(GO:0005838)
0.0	0.2	GO:0042613	MHC class II protein complex(GO:0042613)
0.0	0.0	GO:0032777	Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.0	0.0	GO:0072487	MSL complex(GO:0072487)
0.0	0.1	GO:0030056	hemidesmosome(GO:0030056)
0.0	0.0	GO:0070188	obsolete Stn1-Ten1 complex(GO:0070188)
0.0	0.0	GO:0045323	interleukin-1 receptor complex(GO:0045323)
0.0	0.1	GO:0005678	obsolete chromatin assembly complex(GO:0005678)
0.0	0.0	GO:0033185	mannosyltransferase complex(GO:0031501) dolichol-phosphate-mannose synthase complex(GO:0033185)
0.0	0.3	GO:0005626	obsolete insoluble fraction(GO:0005626)
0.0	0.0	GO:0002139	stereocilia coupling link(GO:0002139) stereocilia ankle link(GO:0002141) stereocilia ankle link complex(GO:0002142)
0.0	0.1	GO:0042597	outer membrane-bounded periplasmic space(GO:0030288) periplasmic space(GO:0042597)
0.0	0.3	GO:0032587	ruffle membrane(GO:0032587)
0.0	0.1	GO:0000784	nuclear chromosome, telomeric region(GO:0000784)
0.0	0.5	GO:0005747	mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0	1.2	GO:0000151	ubiquitin ligase complex(GO:0000151)
0.0	0.0	GO:0031933	telomeric heterochromatin(GO:0031933)
0.0	0.0	GO:0070938	contractile ring(GO:0070938)
0.0	0.0	GO:0001931	uropod(GO:0001931) cell trailing edge(GO:0031254)
0.0	0.2	GO:0032982	myosin filament(GO:0032982)
0.0	0.0	GO:0042587	glycogen granule(GO:0042587)
0.0	0.0	GO:0030868	smooth endoplasmic reticulum membrane(GO:0030868) smooth endoplasmic reticulum part(GO:0097425)
0.0	0.4	GO:0030173	integral component of Golgi membrane(GO:0030173)
0.0	0.0	GO:0005594	collagen type IX trimer(GO:0005594)
0.0	0.1	GO:0035253	ciliary rootlet(GO:0035253)
0.0	0.1	GO:0005868	cytoplasmic dynein complex(GO:0005868)
0.0	0.2	GO:0000307	cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.0	0.2	GO:0005858	axonemal dynein complex(GO:0005858)
0.0	0.0	GO:0046696	lipopolysaccharide receptor complex(GO:0046696)
0.0	0.0	GO:0016600	flotillin complex(GO:0016600)
0.0	1.0	GO:0031965	nuclear membrane(GO:0031965)
0.0	0.2	GO:0030530	obsolete heterogeneous nuclear ribonucleoprotein complex(GO:0030530)
0.0	0.1	GO:0000781	chromosome, telomeric region(GO:0000781)
0.0	2.4	GO:0005667	transcription factor complex(GO:0005667)
0.0	0.0	GO:0071438	invadopodium membrane(GO:0071438)
0.0	0.0	GO:0031228	intrinsic component of Golgi membrane(GO:0031228)
0.0	3.0	GO:0005768	endosome(GO:0005768)
0.0	0.0	GO:0043240	Fanconi anaemia nuclear complex(GO:0043240)
0.0	0.2	GO:0019861	obsolete flagellum(GO:0019861)
0.0	0.0	GO:0034385	very-low-density lipoprotein particle(GO:0034361) triglyceride-rich lipoprotein particle(GO:0034385)
0.0	0.0	GO:0030684	preribosome(GO:0030684)
0.0	0.1	GO:0090568	NuRD complex(GO:0016581) CHD-type complex(GO:0090545) nuclear transcriptional repressor complex(GO:0090568)
0.0	0.2	GO:0016010	dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.0	0.0	GO:0034362	low-density lipoprotein particle(GO:0034362)
0.0	0.1	GO:0016235	aggresome(GO:0016235)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.3	0.9	GO:0046935	1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.3	0.8	GO:0035184	histone threonine kinase activity(GO:0035184)
0.2	0.6	GO:0005250	A-type (transient outward) potassium channel activity(GO:0005250)
0.2	0.5	GO:0031628	opioid receptor binding(GO:0031628)
0.2	2.7	GO:0043027	cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.2	1.6	GO:0016493	C-C chemokine receptor activity(GO:0016493)
0.2	0.5	GO:0004911	interleukin-2 receptor activity(GO:0004911)
0.1	1.7	GO:0004697	protein kinase C activity(GO:0004697)
0.1	0.4	GO:0017162	aryl hydrocarbon receptor binding(GO:0017162)
0.1	0.4	GO:0005094	Rho GDP-dissociation inhibitor activity(GO:0005094)
0.1	0.4	GO:0030375	thyroid hormone receptor coactivator activity(GO:0030375)
0.1	0.4	GO:0016309	1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
0.1	0.4	GO:0003836	beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.1	0.5	GO:0004784	superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
0.1	0.8	GO:0004691	cAMP-dependent protein kinase activity(GO:0004691)
0.1	0.5	GO:0070410	co-SMAD binding(GO:0070410)
0.1	0.5	GO:0004904	interferon receptor activity(GO:0004904)
0.1	0.5	GO:0052813	phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) phosphatidylinositol bisphosphate kinase activity(GO:0052813)
0.1	0.3	GO:0008454	alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.1	0.6	GO:0016494	C-X-C chemokine receptor activity(GO:0016494)
0.1	0.5	GO:0005131	growth hormone receptor binding(GO:0005131)
0.1	0.4	GO:0004974	leukotriene receptor activity(GO:0004974)
0.1	0.4	GO:0008607	phosphorylase kinase regulator activity(GO:0008607)
0.1	0.7	GO:0034713	type I transforming growth factor beta receptor binding(GO:0034713)
0.1	0.3	GO:0033691	sialic acid binding(GO:0033691)
0.1	0.4	GO:0004774	succinate-CoA ligase activity(GO:0004774)
0.1	0.3	GO:0015204	urea transmembrane transporter activity(GO:0015204)
0.1	0.4	GO:0005314	high-affinity glutamate transmembrane transporter activity(GO:0005314)
0.1	0.1	GO:0010485	H4 histone acetyltransferase activity(GO:0010485)
0.1	0.2	GO:0005176	ErbB-2 class receptor binding(GO:0005176)
0.1	3.0	GO:0101005	thiol-dependent ubiquitin-specific protease activity(GO:0004843) thiol-dependent ubiquitinyl hydrolase activity(GO:0036459) ubiquitinyl hydrolase activity(GO:0101005)
0.1	0.7	GO:0070411	I-SMAD binding(GO:0070411)
0.1	0.3	GO:0022897	peptide:proton symporter activity(GO:0015333) proton-dependent peptide secondary active transmembrane transporter activity(GO:0022897)
0.1	0.5	GO:0070087	chromo shadow domain binding(GO:0070087)
0.1	0.3	GO:0015925	galactosidase activity(GO:0015925)
0.1	0.1	GO:0019958	C-X-C chemokine binding(GO:0019958) interleukin-8 binding(GO:0019959)
0.1	0.2	GO:0005025	transforming growth factor beta receptor activity, type I(GO:0005025)
0.1	0.4	GO:0015271	outward rectifier potassium channel activity(GO:0015271)
0.1	0.2	GO:0004311	farnesyltranstransferase activity(GO:0004311)
0.1	0.5	GO:0043539	protein serine/threonine kinase activator activity(GO:0043539)
0.1	0.2	GO:0016312	inositol bisphosphate phosphatase activity(GO:0016312)
0.1	0.2	GO:0042156	obsolete zinc-mediated transcriptional activator activity(GO:0042156)
0.1	0.6	GO:0016273	arginine N-methyltransferase activity(GO:0016273) protein-arginine N-methyltransferase activity(GO:0016274)
0.1	1.0	GO:0030159	receptor signaling complex scaffold activity(GO:0030159)
0.1	0.2	GO:0003953	NAD+ nucleosidase activity(GO:0003953)
0.1	0.1	GO:0016361	activin receptor activity, type I(GO:0016361)
0.1	0.9	GO:0005095	GTPase inhibitor activity(GO:0005095)
0.1	0.6	GO:0015385	sodium:proton antiporter activity(GO:0015385)
0.1	0.2	GO:0004875	complement receptor activity(GO:0004875)
0.1	0.3	GO:0030911	TPR domain binding(GO:0030911)
0.1	0.2	GO:0043141	ATP-dependent 5'-3' DNA helicase activity(GO:0043141)
0.1	0.2	GO:0016149	translation release factor activity, codon specific(GO:0016149)
0.1	0.2	GO:0001758	retinal dehydrogenase activity(GO:0001758)
0.1	2.3	GO:0004715	non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.1	0.5	GO:0030332	cyclin binding(GO:0030332)
0.1	0.2	GO:0004740	pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.1	0.2	GO:0005087	Ran guanyl-nucleotide exchange factor activity(GO:0005087)
0.1	0.5	GO:0005388	calcium-transporting ATPase activity(GO:0005388)
0.1	0.2	GO:0004321	fatty-acyl-CoA synthase activity(GO:0004321)
0.1	0.3	GO:0015520	tetracycline:proton antiporter activity(GO:0015520)
0.1	0.4	GO:0042043	neurexin family protein binding(GO:0042043)
0.1	0.2	GO:0046975	histone methyltransferase activity (H3-K36 specific)(GO:0046975)
0.1	0.2	GO:0005092	GDP-dissociation inhibitor activity(GO:0005092)
0.1	1.8	GO:0003725	double-stranded RNA binding(GO:0003725)
0.1	0.2	GO:0003747	translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079)
0.1	0.2	GO:0034237	protein kinase A regulatory subunit binding(GO:0034237)
0.1	0.1	GO:0000268	peroxisome targeting sequence binding(GO:0000268)
0.1	0.2	GO:0015379	potassium:chloride symporter activity(GO:0015379)
0.1	0.4	GO:0016832	aldehyde-lyase activity(GO:0016832)
0.1	0.2	GO:1990939	ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574) ATP-dependent microtubule motor activity(GO:1990939)
0.1	1.0	GO:0005164	tumor necrosis factor receptor binding(GO:0005164)
0.1	0.4	GO:0051766	inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440) inositol trisphosphate kinase activity(GO:0051766)
0.1	0.2	GO:0005220	inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.1	0.5	GO:0046625	sphingolipid binding(GO:0046625)
0.1	0.7	GO:0008417	fucosyltransferase activity(GO:0008417)
0.1	0.2	GO:0008420	CTD phosphatase activity(GO:0008420)
0.1	0.3	GO:0003691	double-stranded telomeric DNA binding(GO:0003691)
0.0	0.0	GO:0051880	G-quadruplex DNA binding(GO:0051880)
0.0	0.2	GO:0015198	oligopeptide transporter activity(GO:0015198) oligopeptide transmembrane transporter activity(GO:0035673)
0.0	0.2	GO:0051864	histone demethylase activity (H3-K36 specific)(GO:0051864)
0.0	1.2	GO:0003950	NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.0	0.2	GO:0010340	carboxyl-O-methyltransferase activity(GO:0010340) protein carboxyl O-methyltransferase activity(GO:0051998)
0.0	0.1	GO:0017159	pantetheine hydrolase activity(GO:0017159)
0.0	0.3	GO:0031996	thioesterase binding(GO:0031996)
0.0	0.2	GO:0099604	calcium-release channel activity(GO:0015278) ligand-gated calcium channel activity(GO:0099604)
0.0	0.1	GO:0000828	inositol hexakisphosphate kinase activity(GO:0000828) inositol hexakisphosphate 5-kinase activity(GO:0000832)
0.0	0.2	GO:0008140	cAMP response element binding protein binding(GO:0008140)
0.0	0.2	GO:0051637	obsolete Gram-positive bacterial cell surface binding(GO:0051637)
0.0	0.1	GO:0004607	phosphatidylcholine-sterol O-acyltransferase activity(GO:0004607)
0.0	0.1	GO:0034236	protein kinase A catalytic subunit binding(GO:0034236)
0.0	0.0	GO:0035197	siRNA binding(GO:0035197)
0.0	0.3	GO:0051400	BH domain binding(GO:0051400)
0.0	0.3	GO:0030676	Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0	0.1	GO:0004517	nitric-oxide synthase activity(GO:0004517)
0.0	0.1	GO:0042895	antibiotic transporter activity(GO:0042895)
0.0	0.1	GO:0032794	GTPase activating protein binding(GO:0032794)
0.0	0.3	GO:0004126	cytidine deaminase activity(GO:0004126)
0.0	0.5	GO:0043015	gamma-tubulin binding(GO:0043015)
0.0	0.1	GO:0003829	beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity(GO:0003829)
0.0	0.4	GO:0034593	phosphatidylinositol bisphosphate phosphatase activity(GO:0034593)
0.0	0.4	GO:0030742	GTP-dependent protein binding(GO:0030742)
0.0	0.1	GO:0008174	mRNA methyltransferase activity(GO:0008174)
0.0	0.3	GO:0000014	single-stranded DNA endodeoxyribonuclease activity(GO:0000014)
0.0	0.4	GO:0008195	phosphatidate phosphatase activity(GO:0008195)
0.0	0.1	GO:0005049	nuclear export signal receptor activity(GO:0005049)
0.0	0.2	GO:0005521	lamin binding(GO:0005521)
0.0	0.1	GO:0031434	mitogen-activated protein kinase kinase binding(GO:0031434)
0.0	0.5	GO:0031593	polyubiquitin binding(GO:0031593)
0.0	0.3	GO:0042288	MHC class I protein binding(GO:0042288)
0.0	0.1	GO:0004582	dolichyl-phosphate beta-D-mannosyltransferase activity(GO:0004582)
0.0	0.2	GO:0004046	aminoacylase activity(GO:0004046)
0.0	0.2	GO:0008510	sodium:bicarbonate symporter activity(GO:0008510)
0.0	0.8	GO:0051059	NF-kappaB binding(GO:0051059)
0.0	0.2	GO:0005315	inorganic phosphate transmembrane transporter activity(GO:0005315)
0.0	0.1	GO:0043008	ATP-dependent protein binding(GO:0043008)
0.0	0.3	GO:0030507	spectrin binding(GO:0030507)
0.0	0.2	GO:0017176	phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.0	0.3	GO:0008553	hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.0	0.3	GO:0004726	non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.0	0.2	GO:0031702	type 1 angiotensin receptor binding(GO:0031702)
0.0	0.0	GO:0008179	adenylate cyclase binding(GO:0008179)
0.0	0.1	GO:0061731	ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
0.0	0.2	GO:0031013	troponin I binding(GO:0031013)
0.0	0.2	GO:0001637	G-protein coupled chemoattractant receptor activity(GO:0001637) chemokine receptor activity(GO:0004950)
0.0	0.1	GO:0019239	deaminase activity(GO:0019239)
0.0	0.3	GO:0008494	translation activator activity(GO:0008494)
0.0	0.2	GO:0017070	U6 snRNA binding(GO:0017070)
0.0	0.1	GO:0016882	cyclo-ligase activity(GO:0016882)
0.0	0.2	GO:0004528	phosphodiesterase I activity(GO:0004528)
0.0	0.3	GO:0030276	clathrin binding(GO:0030276)
0.0	0.1	GO:0070492	oligosaccharide binding(GO:0070492)
0.0	0.2	GO:0004047	aminomethyltransferase activity(GO:0004047)
0.0	0.5	GO:0015026	coreceptor activity(GO:0015026)
0.0	0.1	GO:0030548	acetylcholine receptor regulator activity(GO:0030548) neurotransmitter receptor regulator activity(GO:0099602)
0.0	0.5	GO:0005246	calcium channel regulator activity(GO:0005246)
0.0	0.2	GO:0009922	fatty acid elongase activity(GO:0009922)
0.0	0.1	GO:0003985	acetyl-CoA C-acetyltransferase activity(GO:0003985)
0.0	0.2	GO:0000405	bubble DNA binding(GO:0000405)
0.0	0.2	GO:0001609	G-protein coupled adenosine receptor activity(GO:0001609)
0.0	0.1	GO:0005229	intracellular calcium activated chloride channel activity(GO:0005229)
0.0	0.7	GO:0016814	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines(GO:0016814)
0.0	0.1	GO:0001591	dopamine neurotransmitter receptor activity, coupled via Gi/Go(GO:0001591)
0.0	0.7	GO:0001608	G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.0	0.2	GO:0060229	lipase activator activity(GO:0060229)
0.0	0.2	GO:0015166	polyol transmembrane transporter activity(GO:0015166)
0.0	0.2	GO:0015355	secondary active monocarboxylate transmembrane transporter activity(GO:0015355)
0.0	0.1	GO:0047756	chondroitin 4-sulfotransferase activity(GO:0047756)
0.0	0.2	GO:0004568	chitinase activity(GO:0004568)
0.0	0.2	GO:0016520	growth hormone-releasing hormone receptor activity(GO:0016520)
0.0	0.1	GO:0004677	DNA-dependent protein kinase activity(GO:0004677)
0.0	0.0	GO:0043140	ATP-dependent 3'-5' DNA helicase activity(GO:0043140)
0.0	0.2	GO:0015057	thrombin receptor activity(GO:0015057)
0.0	0.1	GO:0035198	miRNA binding(GO:0035198)
0.0	0.7	GO:0002039	p53 binding(GO:0002039)
0.0	0.1	GO:0030292	protein tyrosine kinase inhibitor activity(GO:0030292)
0.0	0.1	GO:0004999	vasoactive intestinal polypeptide receptor activity(GO:0004999)
0.0	0.1	GO:0070579	methylcytosine dioxygenase activity(GO:0070579)
0.0	0.4	GO:0005487	nucleocytoplasmic transporter activity(GO:0005487)
0.0	0.1	GO:0004045	aminoacyl-tRNA hydrolase activity(GO:0004045)
0.0	0.1	GO:0004739	pyruvate dehydrogenase activity(GO:0004738) pyruvate dehydrogenase (acetyl-transferring) activity(GO:0004739)
0.0	0.1	GO:0015038	glutathione disulfide oxidoreductase activity(GO:0015038)
0.0	0.1	GO:0008327	methyl-CpG binding(GO:0008327)
0.0	0.3	GO:0004579	dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.0	0.1	GO:0004844	uracil DNA N-glycosylase activity(GO:0004844) deaminated base DNA N-glycosylase activity(GO:0097506)
0.0	0.1	GO:0061133	endopeptidase activator activity(GO:0061133)
0.0	0.1	GO:0008568	microtubule-severing ATPase activity(GO:0008568)
0.0	0.1	GO:0004144	diacylglycerol O-acyltransferase activity(GO:0004144)
0.0	0.1	GO:0004566	beta-glucuronidase activity(GO:0004566)
0.0	0.2	GO:0004017	adenylate kinase activity(GO:0004017)
0.0	0.1	GO:0055103	ligase regulator activity(GO:0055103) ubiquitin-protein transferase regulator activity(GO:0055106)
0.0	0.1	GO:0031545	procollagen-proline 4-dioxygenase activity(GO:0004656) peptidyl-proline 4-dioxygenase activity(GO:0031545)
0.0	0.3	GO:0043022	ribosome binding(GO:0043022)
0.0	0.3	GO:0003857	3-hydroxyacyl-CoA dehydrogenase activity(GO:0003857)
0.0	0.0	GO:0004706	JUN kinase kinase kinase activity(GO:0004706)
0.0	0.1	GO:0030955	potassium ion binding(GO:0030955)
0.0	0.3	GO:0042162	telomeric DNA binding(GO:0042162)
0.0	0.1	GO:0005499	vitamin D binding(GO:0005499)
0.0	0.1	GO:0004427	inorganic diphosphatase activity(GO:0004427)
0.0	1.5	GO:0004197	cysteine-type endopeptidase activity(GO:0004197)
0.0	0.1	GO:0031701	angiotensin receptor binding(GO:0031701)
0.0	0.1	GO:0001965	G-protein alpha-subunit binding(GO:0001965)
0.0	0.9	GO:0004177	aminopeptidase activity(GO:0004177)
0.0	0.8	GO:0001104	RNA polymerase II transcription cofactor activity(GO:0001104)
0.0	0.1	GO:0019211	phosphatase activator activity(GO:0019211)
0.0	0.5	GO:0008601	protein phosphatase type 2A regulator activity(GO:0008601)
0.0	0.1	GO:0042978	ornithine decarboxylase activator activity(GO:0042978)
0.0	0.1	GO:0004952	dopamine neurotransmitter receptor activity(GO:0004952)
0.0	0.1	GO:0016748	succinyltransferase activity(GO:0016748)
0.0	0.1	GO:0000064	L-ornithine transmembrane transporter activity(GO:0000064)
0.0	0.1	GO:0004826	phenylalanine-tRNA ligase activity(GO:0004826)
0.0	0.1	GO:0050815	phosphoserine binding(GO:0050815)
0.0	0.2	GO:0008312	7S RNA binding(GO:0008312)
0.0	0.2	GO:0003785	actin monomer binding(GO:0003785)
0.0	0.1	GO:0070053	thrombospondin receptor activity(GO:0070053)
0.0	0.2	GO:0070402	NADPH binding(GO:0070402)
0.0	0.3	GO:0005031	tumor necrosis factor-activated receptor activity(GO:0005031)
0.0	0.3	GO:0004602	glutathione peroxidase activity(GO:0004602)
0.0	0.2	GO:0000155	phosphorelay sensor kinase activity(GO:0000155)
0.0	0.2	GO:0005160	transforming growth factor beta receptor binding(GO:0005160)
0.0	0.3	GO:0005391	sodium:potassium-exchanging ATPase activity(GO:0005391)
0.0	0.2	GO:0050786	RAGE receptor binding(GO:0050786)
0.0	0.7	GO:0016831	carboxy-lyase activity(GO:0016831)
0.0	0.1	GO:0052650	NADP-retinol dehydrogenase activity(GO:0052650)
0.0	0.1	GO:0016175	superoxide-generating NADPH oxidase activity(GO:0016175)
0.0	0.5	GO:0003746	translation elongation factor activity(GO:0003746)
0.0	0.1	GO:0008020	G-protein coupled photoreceptor activity(GO:0008020)
0.0	0.1	GO:0015651	quaternary ammonium group transmembrane transporter activity(GO:0015651)
0.0	0.1	GO:0050220	prostaglandin-E synthase activity(GO:0050220)
0.0	0.1	GO:0051734	ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity(GO:0046404) polydeoxyribonucleotide kinase activity(GO:0051733) ATP-dependent polynucleotide kinase activity(GO:0051734)
0.0	0.5	GO:0005484	SNAP receptor activity(GO:0005484)
0.0	0.1	GO:0030343	vitamin D3 25-hydroxylase activity(GO:0030343) vitamin D 25-hydroxylase activity(GO:0070643)
0.0	2.2	GO:0017124	SH3 domain binding(GO:0017124)
0.0	0.0	GO:0050897	cobalt ion binding(GO:0050897)
0.0	0.2	GO:0008536	Ran GTPase binding(GO:0008536)
0.0	0.2	GO:0048487	beta-tubulin binding(GO:0048487)
0.0	0.0	GO:0050431	transforming growth factor beta binding(GO:0050431)
0.0	0.1	GO:0015174	basic amino acid transmembrane transporter activity(GO:0015174)
0.0	0.1	GO:0003831	beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity(GO:0003831)
0.0	0.1	GO:0008853	exodeoxyribonuclease III activity(GO:0008853)
0.0	0.1	GO:0046923	ER retention sequence binding(GO:0046923)
0.0	0.1	GO:0036002	pre-mRNA binding(GO:0036002)
0.0	0.1	GO:0004814	arginine-tRNA ligase activity(GO:0004814)
0.0	0.1	GO:0047238	glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity(GO:0047238)
0.0	0.1	GO:0016723	oxidoreductase activity, oxidizing metal ions, NAD or NADP as acceptor(GO:0016723)
0.0	0.2	GO:0042166	acetylcholine binding(GO:0042166)
0.0	0.2	GO:0016679	ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors(GO:0016679) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.0	0.1	GO:0015165	pyrimidine nucleotide-sugar transmembrane transporter activity(GO:0015165)
0.0	0.0	GO:0060590	ATPase regulator activity(GO:0060590)
0.0	0.1	GO:0004995	tachykinin receptor activity(GO:0004995)
0.0	0.4	GO:0004435	phosphatidylinositol phospholipase C activity(GO:0004435)
0.0	0.0	GO:0015252	hydrogen ion channel activity(GO:0015252)
0.0	0.3	GO:0005086	ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0	0.4	GO:0004683	calmodulin-dependent protein kinase activity(GO:0004683)
0.0	0.1	GO:0003986	acetyl-CoA hydrolase activity(GO:0003986)
0.0	0.0	GO:0003945	N-acetyllactosamine synthase activity(GO:0003945)
0.0	0.1	GO:0008474	palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.0	0.2	GO:0070491	repressing transcription factor binding(GO:0070491)
0.0	0.5	GO:0003724	RNA helicase activity(GO:0003724)
0.0	0.2	GO:0015464	acetylcholine receptor activity(GO:0015464)
0.0	0.1	GO:0016530	metallochaperone activity(GO:0016530)
0.0	0.4	GO:0016891	endoribonuclease activity, producing 5'-phosphomonoesters(GO:0016891)
0.0	0.1	GO:0004476	mannose-6-phosphate isomerase activity(GO:0004476)
0.0	0.1	GO:0004307	ethanolaminephosphotransferase activity(GO:0004307)
0.0	0.2	GO:0004659	prenyltransferase activity(GO:0004659)
0.0	0.2	GO:0035251	UDP-glucosyltransferase activity(GO:0035251)
0.0	0.1	GO:0031624	ubiquitin conjugating enzyme binding(GO:0031624) ubiquitin-like protein conjugating enzyme binding(GO:0044390)
0.0	0.1	GO:0016416	carnitine O-palmitoyltransferase activity(GO:0004095) O-palmitoyltransferase activity(GO:0016416)
0.0	0.0	GO:0010861	thyroid hormone receptor activator activity(GO:0010861)
0.0	0.1	GO:0005138	interleukin-6 receptor binding(GO:0005138)
0.0	0.2	GO:0003841	1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841) lysophosphatidic acid acyltransferase activity(GO:0042171) lysophospholipid acyltransferase activity(GO:0071617)
0.0	0.1	GO:0016886	ligase activity, forming phosphoric ester bonds(GO:0016886)
0.0	0.0	GO:0017169	CDP-alcohol phosphatidyltransferase activity(GO:0017169)
0.0	0.9	GO:0008301	DNA binding, bending(GO:0008301)
0.0	0.1	GO:0004694	eukaryotic translation initiation factor 2alpha kinase activity(GO:0004694)
0.0	0.1	GO:0031849	olfactory receptor binding(GO:0031849)
0.0	0.0	GO:0034187	obsolete apolipoprotein E binding(GO:0034187)
0.0	0.1	GO:0003701	obsolete RNA polymerase I transcription factor activity(GO:0003701)
0.0	0.1	GO:0016308	1-phosphatidylinositol-4-phosphate 5-kinase activity(GO:0016308)
0.0	0.2	GO:0043014	alpha-tubulin binding(GO:0043014)
0.0	0.8	GO:0042393	histone binding(GO:0042393)
0.0	0.1	GO:0017108	5'-flap endonuclease activity(GO:0017108)
0.0	0.0	GO:0000104	succinate dehydrogenase activity(GO:0000104)
0.0	0.1	GO:0004614	phosphoglucomutase activity(GO:0004614)
0.0	0.1	GO:0008171	O-methyltransferase activity(GO:0008171)
0.0	0.1	GO:0003828	alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.0	0.2	GO:0016884	carbon-nitrogen ligase activity, with glutamine as amido-N-donor(GO:0016884)
0.0	0.1	GO:0004563	beta-N-acetylhexosaminidase activity(GO:0004563)
0.0	0.1	GO:0004300	enoyl-CoA hydratase activity(GO:0004300)
0.0	0.3	GO:0008484	sulfuric ester hydrolase activity(GO:0008484)
0.0	0.2	GO:0017017	MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.0	0.1	GO:0016922	ligand-dependent nuclear receptor binding(GO:0016922)
0.0	0.1	GO:0016774	phosphotransferase activity, carboxyl group as acceptor(GO:0016774)
0.0	0.1	GO:0042979	ornithine decarboxylase inhibitor activity(GO:0008073) ornithine decarboxylase regulator activity(GO:0042979)
0.0	0.0	GO:0016406	carnitine O-acyltransferase activity(GO:0016406)
0.0	0.1	GO:0008745	N-acetylmuramoyl-L-alanine amidase activity(GO:0008745)
0.0	0.1	GO:0005381	iron ion transmembrane transporter activity(GO:0005381)
0.0	0.3	GO:0048306	calcium-dependent protein binding(GO:0048306)
0.0	0.1	GO:0043425	bHLH transcription factor binding(GO:0043425)
0.0	0.1	GO:0004767	sphingomyelin phosphodiesterase activity(GO:0004767)
0.0	0.2	GO:0005123	death receptor binding(GO:0005123)
0.0	0.1	GO:0008649	rRNA methyltransferase activity(GO:0008649)
0.0	0.1	GO:0002060	purine nucleobase binding(GO:0002060)
0.0	0.3	GO:0004708	MAP kinase kinase activity(GO:0004708)
0.0	0.2	GO:0043499	obsolete eukaryotic cell surface binding(GO:0043499)
0.0	0.2	GO:0015248	sterol transporter activity(GO:0015248)
0.0	0.1	GO:0008889	glycerophosphodiester phosphodiesterase activity(GO:0008889)
0.0	0.0	GO:0001537	N-acetylgalactosamine 4-O-sulfotransferase activity(GO:0001537)
0.0	0.1	GO:0016670	oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor(GO:0016670)
0.0	0.4	GO:0004693	cyclin-dependent protein serine/threonine kinase activity(GO:0004693) cyclin-dependent protein kinase activity(GO:0097472)
0.0	0.1	GO:0048531	beta-1,3-galactosyltransferase activity(GO:0048531)
0.0	0.1	GO:0001848	complement binding(GO:0001848)
0.0	0.0	GO:0004938	alpha2-adrenergic receptor activity(GO:0004938)
0.0	0.2	GO:0004016	adenylate cyclase activity(GO:0004016)
0.0	0.1	GO:0008517	folic acid transporter activity(GO:0008517)
0.0	0.1	GO:0016944	obsolete RNA polymerase II transcription elongation factor activity(GO:0016944)
0.0	0.1	GO:0015288	porin activity(GO:0015288)
0.0	0.0	GO:0005113	patched binding(GO:0005113)
0.0	0.1	GO:0051018	protein kinase A binding(GO:0051018)
0.0	0.0	GO:0016362	activin receptor activity, type II(GO:0016362)
0.0	0.1	GO:0003906	DNA-(apurinic or apyrimidinic site) lyase activity(GO:0003906)
0.0	0.3	GO:0015002	cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors(GO:0016675) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0	0.0	GO:0008184	glycogen phosphorylase activity(GO:0008184)
0.0	0.0	GO:0070891	lipoteichoic acid binding(GO:0070891)
0.0	0.1	GO:0016888	endodeoxyribonuclease activity, producing 5'-phosphomonoesters(GO:0016888)
0.0	0.1	GO:0070567	cytidylyltransferase activity(GO:0070567)
0.0	0.3	GO:0003823	antigen binding(GO:0003823)
0.0	0.3	GO:0004864	protein phosphatase inhibitor activity(GO:0004864)
0.0	0.1	GO:0032395	MHC class II receptor activity(GO:0032395)
0.0	0.1	GO:0050780	dopamine receptor binding(GO:0050780)
0.0	0.1	GO:0030274	LIM domain binding(GO:0030274)
0.0	0.1	GO:0003873	6-phosphofructo-2-kinase activity(GO:0003873)
0.0	0.0	GO:0042808	obsolete neuronal Cdc2-like kinase binding(GO:0042808)
0.0	0.0	GO:0033829	O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.0	2.8	GO:0019787	ubiquitin-like protein transferase activity(GO:0019787)
0.0	0.1	GO:0019992	diacylglycerol binding(GO:0019992)
0.0	0.2	GO:0016538	cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.0	0.0	GO:0005047	signal recognition particle binding(GO:0005047)
0.0	0.0	GO:0051425	PTB domain binding(GO:0051425)
0.0	0.0	GO:0004516	nicotinate phosphoribosyltransferase activity(GO:0004516)
0.0	0.1	GO:0015924	mannosyl-oligosaccharide mannosidase activity(GO:0015924)
0.0	0.1	GO:0015187	glycine transmembrane transporter activity(GO:0015187)
0.0	0.1	GO:0004703	G-protein coupled receptor kinase activity(GO:0004703)
0.0	0.5	GO:0008234	cysteine-type peptidase activity(GO:0008234)
0.0	0.1	GO:0008048	calcium sensitive guanylate cyclase activator activity(GO:0008048)
0.0	0.1	GO:0001517	N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517)
0.0	0.1	GO:0005221	intracellular cyclic nucleotide activated cation channel activity(GO:0005221) cyclic nucleotide-gated ion channel activity(GO:0043855)
0.0	0.1	GO:0019966	interleukin-1 binding(GO:0019966)
0.0	0.1	GO:0004032	alditol:NADP+ 1-oxidoreductase activity(GO:0004032)
0.0	0.1	GO:0001640	adenylate cyclase inhibiting G-protein coupled glutamate receptor activity(GO:0001640) G-protein coupled glutamate receptor activity(GO:0098988)
0.0	0.2	GO:0019894	kinesin binding(GO:0019894)
0.0	0.0	GO:0008401	retinoic acid 4-hydroxylase activity(GO:0008401)
0.0	0.0	GO:0017069	snRNA binding(GO:0017069)
0.0	0.3	GO:0051087	chaperone binding(GO:0051087)
0.0	0.0	GO:0004449	isocitrate dehydrogenase (NAD+) activity(GO:0004449)
0.0	0.0	GO:0031491	nucleosome binding(GO:0031491)
0.0	0.3	GO:0019003	GDP binding(GO:0019003)
0.0	0.0	GO:0032407	MutSalpha complex binding(GO:0032407)
0.0	0.0	GO:0019166	trans-2-enoyl-CoA reductase (NADPH) activity(GO:0019166)
0.0	0.1	GO:0050733	RS domain binding(GO:0050733)
0.0	0.0	GO:0031014	troponin T binding(GO:0031014)
0.0	0.2	GO:0000049	tRNA binding(GO:0000049)
0.0	0.0	GO:0017081	chloride channel regulator activity(GO:0017081)
0.0	0.0	GO:0004127	cytidylate kinase activity(GO:0004127)
0.0	0.1	GO:0004983	neuropeptide Y receptor activity(GO:0004983)
0.0	0.0	GO:0019863	IgE binding(GO:0019863)
0.0	0.0	GO:0097493	extracellular matrix constituent conferring elasticity(GO:0030023) structural molecule activity conferring elasticity(GO:0097493)
0.0	0.8	GO:0003777	microtubule motor activity(GO:0003777)
0.0	0.1	GO:0008641	small protein activating enzyme activity(GO:0008641)
0.0	0.0	GO:0003923	GPI-anchor transamidase activity(GO:0003923)
0.0	0.0	GO:0032813	tumor necrosis factor receptor superfamily binding(GO:0032813)
0.0	0.3	GO:0019843	rRNA binding(GO:0019843)
0.0	0.0	GO:0070326	very-low-density lipoprotein particle receptor binding(GO:0070326)
0.0	0.1	GO:0008373	sialyltransferase activity(GO:0008373)
0.0	0.1	GO:0031419	cobalamin binding(GO:0031419)
0.0	1.0	GO:0004386	helicase activity(GO:0004386)
0.0	0.5	GO:0003743	translation initiation factor activity(GO:0003743)
0.0	0.1	GO:0051010	microtubule plus-end binding(GO:0051010)
0.0	1.6	GO:0003924	GTPase activity(GO:0003924)
0.0	0.4	GO:0050136	NADH dehydrogenase activity(GO:0003954) NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0	0.1	GO:0017110	nucleoside-diphosphatase activity(GO:0017110)
0.0	0.1	GO:0031432	titin binding(GO:0031432)
0.0	0.0	GO:0003886	DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.0	0.0	GO:0019212	phosphatase inhibitor activity(GO:0019212)
0.0	0.2	GO:0016866	intramolecular transferase activity(GO:0016866)
0.0	0.1	GO:0008173	RNA methyltransferase activity(GO:0008173)
0.0	0.0	GO:0016635	oxidoreductase activity, acting on the CH-CH group of donors, quinone or related compound as acceptor(GO:0016635)
0.0	0.1	GO:0010181	FMN binding(GO:0010181)
0.0	0.0	GO:0080031	methyl indole-3-acetate esterase activity(GO:0080030) methyl salicylate esterase activity(GO:0080031) methyl jasmonate esterase activity(GO:0080032)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.1	PID MYC PATHWAY	C-MYC pathway
0.1	3.8	PID REELIN PATHWAY	Reelin signaling pathway
0.1	0.1	PID IL8 CXCR1 PATHWAY	IL8- and CXCR1-mediated signaling events
0.1	1.2	PID TCR JNK PATHWAY	JNK signaling in the CD4+ TCR pathway
0.1	0.9	ST TYPE I INTERFERON PATHWAY	Type I Interferon (alpha/beta IFN) Pathway
0.1	4.1	PID NFAT TFPATHWAY	Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.1	0.1	PID NFKAPPAB CANONICAL PATHWAY	Canonical NF-kappaB pathway
0.1	0.6	SA FAS SIGNALING	The TNF-type receptor Fas induces apoptosis on ligand binding.
0.1	1.2	PID IL3 PATHWAY	IL3-mediated signaling events
0.1	0.8	SA PTEN PATHWAY	PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.1	4.0	PID TCR PATHWAY	TCR signaling in naïve CD4+ T cells
0.1	2.6	PID NFAT 3PATHWAY	Role of Calcineurin-dependent NFAT signaling in lymphocytes
0.1	0.1	PID GMCSF PATHWAY	GMCSF-mediated signaling events
0.1	0.7	PID SMAD2 3PATHWAY	Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.1	1.7	PID CDC42 REG PATHWAY	Regulation of CDC42 activity
0.1	0.8	PID BETA CATENIN DEG PATHWAY	Degradation of beta catenin
0.1	0.4	ST PAC1 RECEPTOR PATHWAY	PAC1 Receptor Pathway
0.1	0.5	PID P38 GAMMA DELTA PATHWAY	Signaling mediated by p38-gamma and p38-delta
0.1	0.9	ST PHOSPHOINOSITIDE 3 KINASE PATHWAY	PI3K Pathway
0.1	1.0	ST TUMOR NECROSIS FACTOR PATHWAY	Tumor Necrosis Factor Pathway.
0.0	0.2	PID CD8 TCR PATHWAY	TCR signaling in naïve CD8+ T cells
0.0	0.8	PID IL2 PI3K PATHWAY	IL2 signaling events mediated by PI3K
0.0	0.5	ST G ALPHA S PATHWAY	G alpha s Pathway
0.0	0.0	PID CXCR3 PATHWAY	CXCR3-mediated signaling events
0.0	0.5	PID CIRCADIAN PATHWAY	Circadian rhythm pathway
0.0	0.2	PID PI3KCI PATHWAY	Class I PI3K signaling events
0.0	1.0	PID ERBB1 INTERNALIZATION PATHWAY	Internalization of ErbB1
0.0	2.1	PID BETA CATENIN NUC PATHWAY	Regulation of nuclear beta catenin signaling and target gene transcription
0.0	0.1	ST JAK STAT PATHWAY	Jak-STAT Pathway
0.0	0.4	PID IFNG PATHWAY	IFN-gamma pathway
0.0	0.6	PID ARF6 PATHWAY	Arf6 signaling events
0.0	0.1	PID TXA2PATHWAY	Thromboxane A2 receptor signaling
0.0	0.6	PID HIF1A PATHWAY	Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.0	1.7	PID P53 REGULATION PATHWAY	p53 pathway
0.0	0.6	PID TNF PATHWAY	TNF receptor signaling pathway
0.0	0.4	PID PRL SIGNALING EVENTS PATHWAY	Signaling events mediated by PRL
0.0	0.2	SIG BCR SIGNALING PATHWAY	Members of the BCR signaling pathway
0.0	0.7	PID ECADHERIN NASCENT AJ PATHWAY	E-cadherin signaling in the nascent adherens junction
0.0	0.1	PID S1P S1P4 PATHWAY	S1P4 pathway
0.0	0.4	PID THROMBIN PAR4 PATHWAY	PAR4-mediated thrombin signaling events
0.0	0.1	PID WNT NONCANONICAL PATHWAY	Noncanonical Wnt signaling pathway
0.0	0.5	PID CERAMIDE PATHWAY	Ceramide signaling pathway
0.0	0.3	SA MMP CYTOKINE CONNECTION	Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0	0.2	PID WNT CANONICAL PATHWAY	Canonical Wnt signaling pathway
0.0	1.0	PID CASPASE PATHWAY	Caspase cascade in apoptosis
0.0	0.1	PID CD40 PATHWAY	CD40/CD40L signaling
0.0	0.5	PID P38 ALPHA BETA PATHWAY	Regulation of p38-alpha and p38-beta
0.0	0.1	PID IL2 STAT5 PATHWAY	IL2 signaling events mediated by STAT5
0.0	0.3	PID INTEGRIN4 PATHWAY	Alpha6 beta4 integrin-ligand interactions
0.0	0.1	SIG PIP3 SIGNALING IN B LYMPHOCYTES	Genes related to PIP3 signaling in B lymphocytes
0.0	0.5	PID CD8 TCR DOWNSTREAM PATHWAY	Downstream signaling in naïve CD8+ T cells
0.0	0.0	SIG CD40PATHWAYMAP	Genes related to CD40 signaling
0.0	0.8	PID TELOMERASE PATHWAY	Regulation of Telomerase
0.0	0.4	PID IL8 CXCR2 PATHWAY	IL8- and CXCR2-mediated signaling events
0.0	0.1	PID ALK1 PATHWAY	ALK1 signaling events
0.0	1.1	PID SMAD2 3NUCLEAR PATHWAY	Regulation of nuclear SMAD2/3 signaling
0.0	0.1	SA G2 AND M PHASES	Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.0	0.0	SA CASPASE CASCADE	Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.0	0.3	PID FOXO PATHWAY	FoxO family signaling
0.0	0.6	PID LKB1 PATHWAY	LKB1 signaling events
0.0	0.2	PID RHOA PATHWAY	RhoA signaling pathway
0.0	0.1	PID P38 MK2 PATHWAY	p38 signaling mediated by MAPKAP kinases
0.0	0.0	PID TRAIL PATHWAY	TRAIL signaling pathway
0.0	0.4	PID RAC1 PATHWAY	RAC1 signaling pathway
0.0	0.1	PID ANTHRAX PATHWAY	Cellular roles of Anthrax toxin
0.0	0.2	PID EPHRINB REV PATHWAY	Ephrin B reverse signaling
0.0	0.4	PID INTEGRIN A4B1 PATHWAY	Alpha4 beta1 integrin signaling events
0.0	0.3	PID IL12 2PATHWAY	IL12-mediated signaling events
0.0	0.4	PID CONE PATHWAY	Visual signal transduction: Cones
0.0	0.2	PID DELTA NP63 PATHWAY	Validated transcriptional targets of deltaNp63 isoforms
0.0	0.4	PID TGFBR PATHWAY	TGF-beta receptor signaling
0.0	0.2	ST G ALPHA I PATHWAY	G alpha i Pathway
0.0	0.1	ST P38 MAPK PATHWAY	p38 MAPK Pathway
0.0	0.1	ST DIFFERENTIATION PATHWAY IN PC12 CELLS	Differentiation Pathway in PC12 Cells; this is a specific case of PAC1 Receptor Pathway.
0.0	1.1	PID P53 DOWNSTREAM PATHWAY	Direct p53 effectors
0.0	0.2	PID EPHA FWDPATHWAY	EPHA forward signaling
0.0	0.0	PID LPA4 PATHWAY	LPA4-mediated signaling events
0.0	0.4	PID IL4 2PATHWAY	IL4-mediated signaling events
0.0	0.2	ST FAS SIGNALING PATHWAY	Fas Signaling Pathway
0.0	0.4	PID HNF3B PATHWAY	FOXA2 and FOXA3 transcription factor networks
0.0	0.1	PID INTEGRIN2 PATHWAY	Beta2 integrin cell surface interactions
0.0	0.1	PID SYNDECAN 3 PATHWAY	Syndecan-3-mediated signaling events
0.0	0.1	PID MAPK TRK PATHWAY	Trk receptor signaling mediated by the MAPK pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	0.8	REACTOME BINDING AND ENTRY OF HIV VIRION	Genes involved in Binding and entry of HIV virion
0.2	0.2	REACTOME TRAF6 MEDIATED IRF7 ACTIVATION	Genes involved in TRAF6 mediated IRF7 activation
0.2	1.9	REACTOME CD28 DEPENDENT VAV1 PATHWAY	Genes involved in CD28 dependent Vav1 pathway
0.2	1.8	REACTOME GENERATION OF SECOND MESSENGER MOLECULES	Genes involved in Generation of second messenger molecules
0.1	1.4	REACTOME IL 7 SIGNALING	Genes involved in Interleukin-7 signaling
0.1	1.4	REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS	Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.1	1.6	REACTOME N GLYCAN ANTENNAE ELONGATION IN THE MEDIAL TRANS GOLGI	Genes involved in N-glycan antennae elongation in the medial/trans-Golgi
0.1	1.9	REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA	Genes involved in Circadian Repression of Expression by REV-ERBA
0.1	0.8	REACTOME ACTIVATION OF RAC	Genes involved in Activation of Rac
0.1	0.2	REACTOME DCC MEDIATED ATTRACTIVE SIGNALING	Genes involved in DCC mediated attractive signaling
0.1	1.7	REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS	Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.1	1.2	REACTOME RAP1 SIGNALLING	Genes involved in Rap1 signalling
0.1	1.4	REACTOME EFFECTS OF PIP2 HYDROLYSIS	Genes involved in Effects of PIP2 hydrolysis
0.1	0.8	REACTOME IRAK1 RECRUITS IKK COMPLEX	Genes involved in IRAK1 recruits IKK complex
0.1	0.5	REACTOME CTLA4 INHIBITORY SIGNALING	Genes involved in CTLA4 inhibitory signaling
0.1	1.7	REACTOME G0 AND EARLY G1	Genes involved in G0 and Early G1
0.1	3.3	REACTOME INTERFERON GAMMA SIGNALING	Genes involved in Interferon gamma signaling
0.1	0.7	REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS	Genes involved in Signal regulatory protein (SIRP) family interactions
0.1	0.6	REACTOME NFKB ACTIVATION THROUGH FADD RIP1 PATHWAY MEDIATED BY CASPASE 8 AND10	Genes involved in NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10
0.1	0.2	REACTOME G PROTEIN ACTIVATION	Genes involved in G-protein activation
0.1	0.3	REACTOME SPRY REGULATION OF FGF SIGNALING	Genes involved in Spry regulation of FGF signaling
0.1	0.9	REACTOME CREB PHOSPHORYLATION THROUGH THE ACTIVATION OF RAS	Genes involved in CREB phosphorylation through the activation of Ras
0.1	0.6	REACTOME IL RECEPTOR SHC SIGNALING	Genes involved in Interleukin receptor SHC signaling
0.1	0.6	REACTOME TRAF6 MEDIATED NFKB ACTIVATION	Genes involved in TRAF6 mediated NF-kB activation
0.1	0.3	REACTOME TRAF3 DEPENDENT IRF ACTIVATION PATHWAY	Genes involved in TRAF3-dependent IRF activation pathway
0.1	0.6	REACTOME SYNTHESIS OF PE	Genes involved in Synthesis of PE
0.0	0.5	REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA	Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.0	0.3	REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX UPON TLR7 8 OR 9 STIMULATION	Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
0.0	0.5	REACTOME PROLONGED ERK ACTIVATION EVENTS	Genes involved in Prolonged ERK activation events
0.0	0.7	REACTOME CTNNB1 PHOSPHORYLATION CASCADE	Genes involved in Beta-catenin phosphorylation cascade
0.0	0.4	REACTOME GRB2 SOS PROVIDES LINKAGE TO MAPK SIGNALING FOR INTERGRINS	Genes involved in GRB2:SOS provides linkage to MAPK signaling for Intergrins
0.0	0.8	REACTOME SIGNALING BY NODAL	Genes involved in Signaling by NODAL
0.0	2.1	REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL	Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0	0.8	REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING	Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.0	0.0	REACTOME CIRCADIAN CLOCK	Genes involved in Circadian Clock
0.0	1.0	REACTOME KINESINS	Genes involved in Kinesins
0.0	0.1	REACTOME NGF SIGNALLING VIA TRKA FROM THE PLASMA MEMBRANE	Genes involved in NGF signalling via TRKA from the plasma membrane
0.0	0.2	REACTOME PLATELET SENSITIZATION BY LDL	Genes involved in Platelet sensitization by LDL
0.0	0.1	REACTOME RIG I MDA5 MEDIATED INDUCTION OF IFN ALPHA BETA PATHWAYS	Genes involved in RIG-I/MDA5 mediated induction of IFN-alpha/beta pathways
0.0	0.6	REACTOME EICOSANOID LIGAND BINDING RECEPTORS	Genes involved in Eicosanoid ligand-binding receptors
0.0	0.2	REACTOME POST NMDA RECEPTOR ACTIVATION EVENTS	Genes involved in Post NMDA receptor activation events
0.0	0.0	REACTOME AUTODEGRADATION OF THE E3 UBIQUITIN LIGASE COP1	Genes involved in Autodegradation of the E3 ubiquitin ligase COP1
0.0	0.5	REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS	Genes involved in Trafficking of GluR2-containing AMPA receptors
0.0	0.0	REACTOME VIF MEDIATED DEGRADATION OF APOBEC3G	Genes involved in Vif-mediated degradation of APOBEC3G
0.0	0.2	REACTOME REGULATION OF INSULIN SECRETION BY GLUCAGON LIKE PEPTIDE1	Genes involved in Regulation of Insulin Secretion by Glucagon-like Peptide-1
0.0	0.5	REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC	Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.0	0.4	REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX	Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.0	0.2	REACTOME PYRUVATE METABOLISM	Genes involved in Pyruvate metabolism
0.0	0.2	REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING	Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
0.0	0.6	REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY	Genes involved in Post-chaperonin tubulin folding pathway
0.0	0.3	REACTOME SEMA3A PAK DEPENDENT AXON REPULSION	Genes involved in Sema3A PAK dependent Axon repulsion
0.0	0.3	REACTOME PROLACTIN RECEPTOR SIGNALING	Genes involved in Prolactin receptor signaling
0.0	0.2	REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION	Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.0	0.4	REACTOME MTORC1 MEDIATED SIGNALLING	Genes involved in mTORC1-mediated signalling
0.0	0.0	REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS	Genes involved in Elevation of cytosolic Ca2+ levels
0.0	0.0	REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE	Genes involved in Norepinephrine Neurotransmitter Release Cycle
0.0	0.1	REACTOME PEPTIDE CHAIN ELONGATION	Genes involved in Peptide chain elongation
0.0	0.0	REACTOME CA DEPENDENT EVENTS	Genes involved in Ca-dependent events
0.0	0.4	REACTOME COSTIMULATION BY THE CD28 FAMILY	Genes involved in Costimulation by the CD28 family
0.0	0.0	REACTOME P53 DEPENDENT G1 DNA DAMAGE RESPONSE	Genes involved in p53-Dependent G1 DNA Damage Response
0.0	0.6	REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE	Genes involved in Sema4D induced cell migration and growth-cone collapse
0.0	0.8	REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS	Genes involved in Apoptotic cleavage of cellular proteins
0.0	0.4	REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING	Genes involved in Formation of ATP by chemiosmotic coupling
0.0	0.5	REACTOME REGULATION OF IFNA SIGNALING	Genes involved in Regulation of IFNA signaling
0.0	1.4	REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES	Genes involved in Chemokine receptors bind chemokines
0.0	0.2	REACTOME DOWNSTREAM TCR SIGNALING	Genes involved in Downstream TCR signaling
0.0	0.2	REACTOME SIGNALING BY FGFR1 MUTANTS	Genes involved in Signaling by FGFR1 mutants
0.0	0.0	REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION	Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.0	0.5	REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS	Genes involved in Termination of O-glycan biosynthesis
0.0	0.4	REACTOME INFLAMMASOMES	Genes involved in Inflammasomes
0.0	0.6	REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE	Genes involved in Synthesis of PIPs at the plasma membrane
0.0	0.4	REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI	Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.0	0.4	REACTOME RECYCLING PATHWAY OF L1	Genes involved in Recycling pathway of L1
0.0	0.1	REACTOME ACYL CHAIN REMODELLING OF PG	Genes involved in Acyl chain remodelling of PG
0.0	0.3	REACTOME HORMONE LIGAND BINDING RECEPTORS	Genes involved in Hormone ligand-binding receptors
0.0	0.2	REACTOME PKA MEDIATED PHOSPHORYLATION OF CREB	Genes involved in PKA-mediated phosphorylation of CREB
0.0	0.2	REACTOME REGULATION OF WATER BALANCE BY RENAL AQUAPORINS	Genes involved in Regulation of Water Balance by Renal Aquaporins
0.0	0.3	REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS	Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.0	0.4	REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS	Genes involved in Regulation of gene expression in beta cells
0.0	0.0	REACTOME RNA POL I PROMOTER OPENING	Genes involved in RNA Polymerase I Promoter Opening
0.0	0.3	REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX	Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.0	0.2	REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS	Genes involved in Membrane binding and targetting of GAG proteins
0.0	0.5	REACTOME G1 PHASE	Genes involved in G1 Phase
0.0	0.2	REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA	Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.0	1.1	REACTOME METABOLISM OF NON CODING RNA	Genes involved in Metabolism of non-coding RNA
0.0	0.4	REACTOME ACTIVATED AMPK STIMULATES FATTY ACID OXIDATION IN MUSCLE	Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle
0.0	0.3	REACTOME METABOLISM OF PORPHYRINS	Genes involved in Metabolism of porphyrins
0.0	0.0	REACTOME REGULATION OF AMPK ACTIVITY VIA LKB1	Genes involved in Regulation of AMPK activity via LKB1
0.0	0.4	REACTOME PRE NOTCH TRANSCRIPTION AND TRANSLATION	Genes involved in Pre-NOTCH Transcription and Translation
0.0	0.4	REACTOME PERK REGULATED GENE EXPRESSION	Genes involved in PERK regulated gene expression
0.0	0.3	REACTOME PREFOLDIN MEDIATED TRANSFER OF SUBSTRATE TO CCT TRIC	Genes involved in Prefoldin mediated transfer of substrate to CCT/TriC
0.0	0.0	REACTOME P75NTR RECRUITS SIGNALLING COMPLEXES	Genes involved in p75NTR recruits signalling complexes
0.0	0.3	REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS	Genes involved in Presynaptic nicotinic acetylcholine receptors
0.0	0.3	REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE	Genes involved in Glutamate Neurotransmitter Release Cycle
0.0	0.5	REACTOME CYTOSOLIC TRNA AMINOACYLATION	Genes involved in Cytosolic tRNA aminoacylation
0.0	0.8	REACTOME GLYCOSPHINGOLIPID METABOLISM	Genes involved in Glycosphingolipid metabolism
0.0	1.3	REACTOME RESPIRATORY ELECTRON TRANSPORT ATP SYNTHESIS BY CHEMIOSMOTIC COUPLING AND HEAT PRODUCTION BY UNCOUPLING PROTEINS	Genes involved in Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins.
0.0	0.3	REACTOME TGF BETA RECEPTOR SIGNALING ACTIVATES SMADS	Genes involved in TGF-beta receptor signaling activates SMADs
0.0	0.1	REACTOME SHC RELATED EVENTS	Genes involved in SHC-related events
0.0	0.3	REACTOME INTERFERON ALPHA BETA SIGNALING	Genes involved in Interferon alpha/beta signaling
0.0	0.3	REACTOME CITRIC ACID CYCLE TCA CYCLE	Genes involved in Citric acid cycle (TCA cycle)
0.0	0.0	REACTOME CYCLIN E ASSOCIATED EVENTS DURING G1 S TRANSITION	Genes involved in Cyclin E associated events during G1/S transition
0.0	0.1	REACTOME ALPHA LINOLENIC ACID ALA METABOLISM	Genes involved in alpha-linolenic acid (ALA) metabolism
0.0	0.8	REACTOME VOLTAGE GATED POTASSIUM CHANNELS	Genes involved in Voltage gated Potassium channels
0.0	0.1	REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY	Genes involved in Regulation of the Fanconi anemia pathway
0.0	0.5	REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS	Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.0	0.1	REACTOME REGULATION OF ORNITHINE DECARBOXYLASE ODC	Genes involved in Regulation of ornithine decarboxylase (ODC)
0.0	0.3	REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM	Genes involved in Branched-chain amino acid catabolism
0.0	0.2	REACTOME CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE	Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
0.0	0.1	REACTOME IL 6 SIGNALING	Genes involved in Interleukin-6 signaling
0.0	0.1	REACTOME P38MAPK EVENTS	Genes involved in p38MAPK events
0.0	0.1	REACTOME THE ROLE OF NEF IN HIV1 REPLICATION AND DISEASE PATHOGENESIS	Genes involved in The role of Nef in HIV-1 replication and disease pathogenesis
0.0	0.3	REACTOME FORMATION OF INCISION COMPLEX IN GG NER	Genes involved in Formation of incision complex in GG-NER
0.0	0.2	REACTOME RESOLUTION OF AP SITES VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY	Genes involved in Resolution of AP sites via the single-nucleotide replacement pathway
0.0	0.4	REACTOME FORMATION OF RNA POL II ELONGATION COMPLEX	Genes involved in Formation of RNA Pol II elongation complex
0.0	0.3	REACTOME MRNA SPLICING MINOR PATHWAY	Genes involved in mRNA Splicing - Minor Pathway
0.0	0.0	REACTOME ENDOSOMAL VACUOLAR PATHWAY	Genes involved in Endosomal/Vacuolar pathway
0.0	1.0	REACTOME MEIOTIC SYNAPSIS	Genes involved in Meiotic Synapsis
0.0	0.2	REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES	Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.0	0.2	REACTOME SIGNALING BY ROBO RECEPTOR	Genes involved in Signaling by Robo receptor
0.0	0.1	REACTOME INTEGRATION OF PROVIRUS	Genes involved in Integration of provirus
0.0	0.0	REACTOME TRANSPORT OF MATURE TRANSCRIPT TO CYTOPLASM	Genes involved in Transport of Mature Transcript to Cytoplasm
0.0	0.2	REACTOME MITOCHONDRIAL TRNA AMINOACYLATION	Genes involved in Mitochondrial tRNA aminoacylation
0.0	0.3	REACTOME CHOLESTEROL BIOSYNTHESIS	Genes involved in Cholesterol biosynthesis
0.0	0.2	REACTOME INTRINSIC PATHWAY	Genes involved in Intrinsic Pathway
0.0	0.2	REACTOME PRE NOTCH EXPRESSION AND PROCESSING	Genes involved in Pre-NOTCH Expression and Processing
0.0	0.2	REACTOME CHONDROITIN SULFATE BIOSYNTHESIS	Genes involved in Chondroitin sulfate biosynthesis
0.0	0.1	REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS	Genes involved in Extrinsic Pathway for Apoptosis
0.0	0.0	REACTOME P53 INDEPENDENT G1 S DNA DAMAGE CHECKPOINT	Genes involved in p53-Independent G1/S DNA damage checkpoint
0.0	0.1	REACTOME LYSOSOME VESICLE BIOGENESIS	Genes involved in Lysosome Vesicle Biogenesis
0.0	0.1	REACTOME CREATION OF C4 AND C2 ACTIVATORS	Genes involved in Creation of C4 and C2 activators
0.0	1.9	REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION	Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.0	0.1	REACTOME CS DS DEGRADATION	Genes involved in CS/DS degradation
0.0	0.1	REACTOME DARPP 32 EVENTS	Genes involved in DARPP-32 events
0.0	0.1	REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS	Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.0	0.1	REACTOME ETHANOL OXIDATION	Genes involved in Ethanol oxidation
0.0	0.1	REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE	Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.0	0.1	REACTOME AMINE DERIVED HORMONES	Genes involved in Amine-derived hormones
0.0	0.3	REACTOME MRNA 3 END PROCESSING	Genes involved in mRNA 3'-end processing
0.0	0.0	REACTOME G2 M DNA DAMAGE CHECKPOINT	Genes involved in G2/M DNA damage checkpoint
0.0	0.2	REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT	Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.0	0.2	REACTOME INTRINSIC PATHWAY FOR APOPTOSIS	Genes involved in Intrinsic Pathway for Apoptosis
0.0	0.1	REACTOME FANCONI ANEMIA PATHWAY	Genes involved in Fanconi Anemia pathway
0.0	0.3	REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS	Genes involved in Sphingolipid de novo biosynthesis

Results for SIX1_SIX3_SIX2

Z-value: 3.50

Motif logo

Transcription factors associated with SIX1_SIX3_SIX2

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

Activity of the SIX1_SIX3_SIX2 motif across conditions

Conditions sorted by the z-value of the SIX1_SIX3_SIX2 motif activity

Top target CREs of the motif:

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of SIX1_SIX3_SIX2

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category:

Gene overrepresentation in curated gene sets: canonical pathways category:

Gene overrepresentation in curated gene sets: REACTOME pathways category: