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ENCODE: H3K4me1 ChIP-Seq of primary human cells
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Results for SIX6

Z-value: 2.37

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Transcription factors associated with SIX6

Gene Symbol Gene ID Gene Info
ENSG00000184302.6 SIX homeobox 6

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE Gene Distance Association probability Pearson corr. coef. P-value Plot
chr14_60974329_60974480SIX612650.4431790.771.6e-02Click!
chr14_60977546_60977697SIX619520.2992270.703.6e-02Click!
chr14_60974122_60974273SIX614720.3925470.442.4e-01Click!
chr14_60975919_60976070SIX63250.881368-0.402.8e-01Click!
chr14_60975240_60975503SIX62980.895997-0.314.2e-01Click!

Activity of the SIX6 motif across conditions

Conditions sorted by the z-value of the SIX6 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE) Target Score Top associated gene Gene Info Distance of CRE to TSS CRE/Gene association probability
chr3_195842946_195843347 1.19 TFRC
transferrin receptor
34086
0.13
chr12_106622335_106622486 1.01 RP11-651L5.2

18324
0.17
chr7_50362495_50362678 0.85 IKZF1
IKAROS family zinc finger 1 (Ikaros)
4659
0.32
chr5_74805113_74805264 0.83 COL4A3BP
collagen, type IV, alpha 3 (Goodpasture antigen) binding protein
2266
0.26
chr5_55883015_55883166 0.82 AC022431.2
Homo sapiens uncharacterized LOC101928448 (LOC101928448), mRNA.
18969
0.22
chr19_7744687_7745032 0.73 TRAPPC5
trafficking protein particle complex 5
870
0.32
chrX_48577151_48577508 0.71 ENSG00000206723
.
5637
0.12
chrX_41969111_41969315 0.66 ENSG00000212560
.
29570
0.22
chr10_5339048_5339261 0.66 AKR1C7P
aldo-keto reductase family 1, member C7, pseudogene
8721
0.21
chrX_44106060_44106211 0.63 EFHC2
EF-hand domain (C-terminal) containing 2
96783
0.09
chr6_137674402_137674583 0.63 IFNGR1
interferon gamma receptor 1
133906
0.05
chr18_18683979_18684149 0.62 ROCK1
Rho-associated, coiled-coil containing protein kinase 1
7748
0.22
chr3_68110298_68110449 0.61 FAM19A1
family with sequence similarity 19 (chemokine (C-C motif)-like), member A1
55000
0.18
chr17_46515212_46515468 0.61 SKAP1
src kinase associated phosphoprotein 1
7759
0.15
chr4_109024677_109024828 0.60 LEF1
lymphoid enhancer-binding factor 1
62705
0.11
chr10_50715946_50716218 0.60 ERCC6
excision repair cross-complementing rodent repair deficiency, complementation group 6
5914
0.18
chr2_42526156_42526376 0.60 EML4
echinoderm microtubule associated protein like 4
2127
0.4
chr5_140967335_140967486 0.59 DIAPH1
diaphanous-related formin 1
358
0.8
chr21_32560064_32560407 0.59 TIAM1
T-cell lymphoma invasion and metastasis 1
57696
0.15
chr1_151027090_151027301 0.58 MLLT11
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
3039
0.11
chr10_87354888_87355039 0.58 RP11-93H12.2

10187
0.22
chr20_5071070_5071221 0.58 ENSG00000212536
.
7977
0.13
chr2_48552472_48552623 0.58 FOXN2
forkhead box N2
10698
0.22
chr2_136815642_136816045 0.58 AC093391.2

45808
0.15
chr15_63837464_63837615 0.57 USP3
ubiquitin specific peptidase 3
715
0.7
chr4_81416077_81416298 0.57 C4orf22
chromosome 4 open reading frame 22
159264
0.04
chr10_52431892_52432067 0.56 SGMS1
sphingomyelin synthase 1
47184
0.12
chr14_91534430_91534736 0.56 C14orf159
chromosome 14 open reading frame 159
7407
0.17
chr11_118210971_118211165 0.56 CD3D
CD3d molecule, delta (CD3-TCR complex)
584
0.62
chr5_139792445_139792699 0.56 ANKHD1
ankyrin repeat and KH domain containing 1
11066
0.11
chr14_22548820_22548971 0.56 ENSG00000238634
.
61992
0.14
chr2_32589085_32589236 0.55 BIRC6
baculoviral IAP repeat containing 6
7064
0.21
chr2_204820724_204820875 0.55 ICOS
inducible T-cell co-stimulator
19296
0.26
chr17_48941843_48942031 0.55 TOB1
transducer of ERBB2, 1
1769
0.26
chrX_20463745_20463896 0.55 ENSG00000252978
.
6406
0.33
chr2_144362891_144363042 0.55 RP11-570L15.1

7395
0.21
chr9_134142900_134143064 0.54 FAM78A
family with sequence similarity 78, member A
2898
0.24
chr6_152508296_152508447 0.54 SYNE1
spectrin repeat containing, nuclear envelope 1
18872
0.28
chr11_68294410_68294561 0.54 PPP6R3
protein phosphatase 6, regulatory subunit 3
7511
0.18
chr16_68105212_68105363 0.54 NFATC3
nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3
13960
0.09
chrX_78290821_78291202 0.54 P2RY10
purinergic receptor P2Y, G-protein coupled, 10
90093
0.1
chr1_114324657_114324917 0.53 PHTF1
putative homeodomain transcription factor 1
22689
0.15
chr6_90794400_90794673 0.53 ENSG00000222078
.
83311
0.09
chr5_55910287_55910438 0.53 AC022431.2
Homo sapiens uncharacterized LOC101928448 (LOC101928448), mRNA.
8303
0.26
chr12_76882061_76882212 0.53 OSBPL8
oxysterol binding protein-like 8
2248
0.44
chr15_63774655_63774806 0.52 USP3
ubiquitin specific peptidase 3
22063
0.21
chr2_106395941_106396479 0.52 NCK2
NCK adaptor protein 2
34022
0.21
chr2_128924253_128924404 0.52 UGGT1
UDP-glucose glycoprotein glucosyltransferase 1
13032
0.23
chr4_90165077_90165348 0.52 GPRIN3
GPRIN family member 3
7133
0.3
chr1_32729524_32729675 0.51 LCK
lymphocyte-specific protein tyrosine kinase
10115
0.09
chr1_90122128_90122321 0.51 LRRC8C
leucine rich repeat containing 8 family, member C
23593
0.16
chr21_36411020_36411357 0.51 RUNX1
runt-related transcription factor 1
10274
0.32
chr1_147404055_147404206 0.51 GPR89B
G protein-coupled receptor 89B
3581
0.26
chr1_28582798_28582949 0.51 SESN2
sestrin 2
3165
0.16
chr16_50743011_50743208 0.50 NOD2
nucleotide-binding oligomerization domain containing 2
2996
0.15
chr16_3178604_3178789 0.50 RP11-473M20.14

604
0.42
chr4_123378511_123378864 0.50 IL2
interleukin 2
807
0.73
chr17_33543898_33544185 0.50 RP11-799D4.4

20959
0.11
chr17_46489763_46490057 0.50 SKAP1
src kinase associated phosphoprotein 1
17642
0.13
chr17_33754878_33755029 0.49 SLFN12
schlafen family member 12
4590
0.17
chr14_50447744_50447895 0.49 C14orf182
chromosome 14 open reading frame 182
26419
0.15
chr7_115856238_115856410 0.49 TES
testis derived transcript (3 LIM domains)
5721
0.23
chr4_109080191_109080589 0.49 LEF1
lymphoid enhancer-binding factor 1
7067
0.24
chr17_37925720_37925871 0.49 IKZF3
IKAROS family zinc finger 3 (Aiolos)
8683
0.13
chr3_36920665_36920816 0.49 TRANK1
tetratricopeptide repeat and ankyrin repeat containing 1
20366
0.22
chr6_152503247_152503398 0.49 SYNE1
spectrin repeat containing, nuclear envelope 1
13823
0.29
chr1_39505386_39505552 0.48 NDUFS5
NADH dehydrogenase (ubiquinone) Fe-S protein 5, 15kDa (NADH-coenzyme Q reductase)
13479
0.17
chr2_178174291_178174464 0.48 NFE2L2
nuclear factor, erythroid 2-like 2
1628
0.24
chr5_118715168_118715319 0.48 TNFAIP8
tumor necrosis factor, alpha-induced protein 8
23513
0.18
chr2_198119149_198119485 0.48 ANKRD44-IT1
ANKRD44 intronic transcript 1 (non-protein coding)
47926
0.12
chr12_46617849_46618103 0.48 SLC38A1
solute carrier family 38, member 1
43508
0.2
chr1_167435716_167435867 0.48 RP11-104L21.2

7893
0.22
chr14_106479881_106480119 0.47 IGHV4-4
immunoglobulin heavy variable 4-4
1397
0.14
chr19_6814065_6814233 0.47 VAV1
vav 1 guanine nucleotide exchange factor
30020
0.12
chrX_123475859_123476089 0.47 SH2D1A
SH2 domain containing 1A
4220
0.35
chr16_71914316_71914975 0.47 ZNF821
zinc finger protein 821
677
0.52
chr5_40669552_40669882 0.47 PTGER4
prostaglandin E receptor 4 (subtype EP4)
9883
0.21
chr1_111210638_111210814 0.47 KCNA3
potassium voltage-gated channel, shaker-related subfamily, member 3
6929
0.19
chr14_100559489_100559669 0.47 EVL
Enah/Vasp-like
3705
0.17
chr12_21607370_21607521 0.47 PYROXD1
pyridine nucleotide-disulphide oxidoreductase domain 1
16596
0.16
chr19_18231095_18231250 0.46 IL12RB1
interleukin 12 receptor, beta 1
21418
0.1
chr2_99090359_99090706 0.46 INPP4A
inositol polyphosphate-4-phosphatase, type I, 107kDa
29119
0.2
chr1_18972493_18972644 0.46 PAX7
paired box 7
14550
0.28
chr6_111411364_111411515 0.46 ENSG00000200926
.
1096
0.48
chr2_238977202_238977353 0.46 SCLY
selenocysteine lyase
821
0.6
chr1_193516704_193516855 0.46 ENSG00000252241
.
184295
0.03
chr1_101394347_101394839 0.46 SLC30A7
solute carrier family 30 (zinc transporter), member 7
32783
0.12
chr14_69462402_69462553 0.45 ACTN1-AS1
ACTN1 antisense RNA 1
15719
0.21
chr13_48794009_48794180 0.45 ITM2B
integral membrane protein 2B
13200
0.25
chr12_112437004_112437163 0.45 TMEM116
transmembrane protein 116
6706
0.17
chr2_109647371_109647603 0.45 EDAR
ectodysplasin A receptor
41659
0.19
chr11_35278448_35278680 0.45 SLC1A2
solute carrier family 1 (glial high affinity glutamate transporter), member 2
8728
0.17
chr2_197100668_197101019 0.45 ENSG00000239161
.
20797
0.17
chr6_88224420_88224571 0.45 ENSG00000206715
.
26332
0.16
chr13_20338338_20338714 0.45 PSPC1
paraspeckle component 1
18531
0.16
chr10_63710610_63710761 0.45 ENSG00000221272
.
23908
0.23
chr2_173295612_173295763 0.45 AC078883.4

2356
0.27
chr7_114868701_114868954 0.45 ENSG00000199764
.
20777
0.29
chr2_26059283_26059434 0.45 ASXL2
additional sex combs like 2 (Drosophila)
41977
0.17
chr8_67597458_67597609 0.44 C8orf44
chromosome 8 open reading frame 44
9079
0.14
chr2_69703654_69703809 0.44 NFU1
NFU1 iron-sulfur cluster scaffold homolog (S. cerevisiae)
38971
0.14
chr8_82010683_82011181 0.44 PAG1
phosphoprotein associated with glycosphingolipid microdomains 1
13371
0.28
chr3_71448390_71448541 0.44 FOXP1
forkhead box P1
94554
0.08
chrX_14869226_14869377 0.44 FANCB
Fanconi anemia, complementation group B
21873
0.21
chr8_130928050_130928201 0.44 FAM49B
family with sequence similarity 49, member B
23815
0.18
chr12_979574_979725 0.44 WNK1
WNK lysine deficient protein kinase 1
1915
0.4
chr1_198605746_198606049 0.44 PTPRC
protein tyrosine phosphatase, receptor type, C
1904
0.42
chr17_71582047_71582198 0.43 RP11-277J6.2

55043
0.12
chr11_104902517_104902668 0.43 CASP1
caspase 1, apoptosis-related cysteine peptidase
1362
0.39
chr3_196473291_196473442 0.43 ENSG00000272359
.
829
0.51
chr2_109598027_109598178 0.43 EDAR
ectodysplasin A receptor
7623
0.3
chr3_149671956_149672107 0.43 PFN2
profilin 2
16157
0.16
chr12_88541141_88541292 0.43 TMTC3
transmembrane and tetratricopeptide repeat containing 3
5132
0.24
chr12_131306489_131306640 0.43 ENSG00000238822
.
6666
0.19
chr18_67605078_67605229 0.43 CD226
CD226 molecule
9502
0.29
chr11_73944165_73944334 0.43 PPME1
protein phosphatase methylesterase 1
2419
0.25
chr12_14544534_14544685 0.43 ATF7IP
activating transcription factor 7 interacting protein
3188
0.32
chr3_101240874_101241025 0.43 SENP7
SUMO1/sentrin specific peptidase 7
8864
0.16
chr12_58174546_58174758 0.43 TSFM
Ts translation elongation factor, mitochondrial
1720
0.14
chr11_13321834_13322130 0.43 ARNTL
aryl hydrocarbon receptor nuclear translocator-like
9551
0.26
chr14_71389272_71389432 0.42 PCNX
pecanex homolog (Drosophila)
14896
0.28
chr1_2950991_2951142 0.42 ACTRT2
actin-related protein T2
13020
0.19
chr3_69255669_69255822 0.42 FRMD4B
FERM domain containing 4B
5696
0.28
chr11_35371647_35371798 0.42 SLC1A2
solute carrier family 1 (glial high affinity glutamate transporter), member 2
48647
0.13
chr14_55759378_55759529 0.42 FBXO34
F-box protein 34
20581
0.21
chrX_135950882_135951033 0.42 ENSG00000206979
.
10473
0.18
chr3_52295389_52295673 0.42 ENSG00000199150
.
6848
0.09
chr1_168490081_168490873 0.42 XCL2
chemokine (C motif) ligand 2
22758
0.22
chr2_28846418_28846636 0.42 PLB1
phospholipase B1
6926
0.22
chr8_61733268_61733687 0.42 RP11-33I11.2

11312
0.29
chr11_14601295_14601599 0.42 PSMA1
proteasome (prosome, macropain) subunit, alpha type, 1
59205
0.12
chr1_66751378_66751529 0.42 PDE4B
phosphodiesterase 4B, cAMP-specific
28123
0.25
chr16_50810796_50811006 0.42 CYLD
cylindromatosis (turban tumor syndrome)
16627
0.12
chr5_156739412_156739563 0.42 CYFIP2
cytoplasmic FMR1 interacting protein 2
1442
0.36
chr12_31956393_31956544 0.42 ENSG00000252421
.
444
0.8
chr1_31513861_31514012 0.42 PUM1
pumilio RNA-binding family member 1
20827
0.2
chr5_78539530_78539681 0.42 JMY
junction mediating and regulatory protein, p53 cofactor
7593
0.19
chr19_43942522_43943043 0.42 TEX101
testis expressed 101
23718
0.12
chr1_200986316_200986721 0.42 KIF21B
kinesin family member 21B
6018
0.2
chr14_52360876_52361221 0.42 GNG2
guanine nucleotide binding protein (G protein), gamma 2
16738
0.17
chr2_136872566_136873100 0.42 CXCR4
chemokine (C-X-C motif) receptor 4
980
0.68
chr3_16990436_16990587 0.42 ENSG00000264818
.
15823
0.22
chr2_102356000_102356151 0.42 MAP4K4
mitogen-activated protein kinase kinase kinase kinase 4
41083
0.2
chr2_169964594_169965040 0.42 AC007556.3

7564
0.23
chr1_40650270_40650421 0.42 ENSG00000207508
.
6830
0.17
chr3_195843351_195843535 0.41 TFRC
transferrin receptor
34383
0.13
chr2_153586108_153586259 0.41 PRPF40A
PRP40 pre-mRNA processing factor 40 homolog A (S. cerevisiae)
11688
0.23
chr1_202599145_202599380 0.41 SYT2
synaptotagmin II
13319
0.2
chr22_40319352_40319503 0.41 GRAP2
GRB2-related adaptor protein 2
3168
0.23
chr14_97586844_97587256 0.41 VRK1
vaccinia related kinase 1
244684
0.02
chr15_72778025_72778176 0.41 ARIH1
ariadne RBR E3 ubiquitin protein ligase 1
11114
0.21
chr9_6782531_6782707 0.41 KDM4C
lysine (K)-specific demethylase 4C
24501
0.24
chrX_20277922_20278180 0.41 RPS6KA3
ribosomal protein S6 kinase, 90kDa, polypeptide 3
6709
0.27
chr3_43079279_43079552 0.41 FAM198A
family with sequence similarity 198, member A
58375
0.1
chr17_76709505_76709686 0.41 CYTH1
cytohesin 1
3512
0.24
chr2_106455137_106455288 0.41 NCK2
NCK adaptor protein 2
12992
0.23
chr1_154926882_154927088 0.41 PBXIP1
pre-B-cell leukemia homeobox interacting protein 1
1595
0.18
chr19_6480330_6480491 0.41 DENND1C
DENN/MADD domain containing 1C
1354
0.24
chr5_55396926_55397077 0.41 ANKRD55
ankyrin repeat domain 55
15777
0.17
chr12_14730993_14731364 0.41 PLBD1
phospholipase B domain containing 1
9895
0.15
chr5_49733708_49733999 0.41 EMB
embigin
3331
0.4
chr3_169873473_169873624 0.41 ENSG00000199536
.
5915
0.19
chr2_69790675_69790826 0.41 ENSG00000207016
.
43444
0.14
chr12_56864817_56864968 0.41 SPRYD4
SPRY domain containing 4
2591
0.17
chr5_112046097_112046248 0.40 APC
adenomatous polyposis coli
2953
0.34
chr5_169695577_169695892 0.40 LCP2
lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa)
1403
0.48
chrX_133056294_133056594 0.40 GPC3
glypican 3
63032
0.13
chr14_66416251_66416409 0.40 CTD-2014B16.3
Uncharacterized protein
54911
0.15
chr2_120968332_120968483 0.40 AC012363.4

5713
0.18
chr17_48965132_48965283 0.40 TOB1
transducer of ERBB2, 1
19868
0.15
chr7_36211224_36211417 0.40 EEPD1
endonuclease/exonuclease/phosphatase family domain containing 1
18443
0.21
chr17_76709763_76709949 0.40 CYTH1
cytohesin 1
3251
0.25
chr8_61440352_61440503 0.40 RAB2A
RAB2A, member RAS oncogene family
10687
0.22
chr18_60872119_60872270 0.40 ENSG00000238988
.
10296
0.23
chr3_105730101_105730252 0.40 CBLB
Cbl proto-oncogene B, E3 ubiquitin protein ligase
141780
0.05
chr2_204809703_204809854 0.40 ICOS
inducible T-cell co-stimulator
8275
0.29
chr1_167617183_167617334 0.40 RP3-455J7.4

17347
0.18
chr7_130066201_130066352 0.40 CEP41
centrosomal protein 41kDa
295
0.87
chr10_73458033_73458184 0.40 C10orf105
chromosome 10 open reading frame 105
21470
0.2
chr14_98484334_98484485 0.40 C14orf64
chromosome 14 open reading frame 64
39948
0.23
chr13_22635764_22635982 0.40 ENSG00000244197
.
271197
0.02
chr4_84139507_84139821 0.40 COQ2
coenzyme Q2 4-hydroxybenzoate polyprenyltransferase
66254
0.11
chr6_74155389_74155663 0.40 MB21D1
Mab-21 domain containing 1
6456
0.1
chr7_86831286_86831437 0.40 DMTF1
cyclin D binding myb-like transcription factor 1
8320
0.18
chr2_197014969_197015443 0.40 RP11-347P5.1

781
0.66
chrX_13268049_13268200 0.40 GS1-600G8.3

60647
0.13
chr6_70524527_70524678 0.40 LMBRD1
LMBR1 domain containing 1
17599
0.26
chr6_135425077_135425228 0.40 HBS1L
HBS1-like (S. cerevisiae)
958
0.62
chr13_74545493_74545644 0.40 KLF12
Kruppel-like factor 12
23618
0.29
chr15_63964059_63964210 0.40 RP11-317G6.1

3211
0.25
chr6_24966109_24966329 0.40 FAM65B
family with sequence similarity 65, member B
30031
0.18
chr1_226861460_226861946 0.39 ITPKB-IT1
ITPKB intronic transcript 1 (non-protein coding)
1065
0.54
chr3_137941537_137941872 0.39 ARMC8
armadillo repeat containing 8
774
0.7
chr1_39744299_39744450 0.39 MACF1
microtubule-actin crosslinking factor 1
10175
0.2
chr8_101324350_101324501 0.39 RNF19A
ring finger protein 19A, RBR E3 ubiquitin protein ligase
1870
0.4
chr6_160897671_160897822 0.39 LPAL2
lipoprotein, Lp(a)-like 2, pseudogene
34293
0.22
chr15_70047304_70047503 0.39 ENSG00000238870
.
24242
0.21
chr13_96333210_96333380 0.39 DNAJC3
DnaJ (Hsp40) homolog, subfamily C, member 3
3883
0.26
chr14_99652901_99653521 0.39 AL162151.4

28458
0.21
chr10_111823074_111823225 0.39 ADD3
adducin 3 (gamma)
55427
0.12

Histogram of CRE-TSS distances for CREs targeted by :

Histogram of

Rank distribution of CRE target scores:

Histogram of target CRE score.

Distribution of target CREs across different genomic regions:

Weighted Piechart of Weighted Piechart of Weighted Piechart of

Network of associatons between targets according to the STRING database.

First level regulatory network of SIX6

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.9 GO:0001911 negative regulation of leukocyte mediated cytotoxicity(GO:0001911)
0.2 0.7 GO:0030854 positive regulation of granulocyte differentiation(GO:0030854)
0.2 0.5 GO:0010459 negative regulation of heart rate(GO:0010459)
0.2 0.5 GO:0045591 positive regulation of regulatory T cell differentiation(GO:0045591)
0.2 0.7 GO:0032237 activation of store-operated calcium channel activity(GO:0032237) regulation of store-operated calcium channel activity(GO:1901339) positive regulation of store-operated calcium channel activity(GO:1901341)
0.2 0.5 GO:0015917 aminophospholipid transport(GO:0015917)
0.2 0.5 GO:0019276 UDP-N-acetylgalactosamine metabolic process(GO:0019276)
0.1 0.3 GO:0002513 tolerance induction to self antigen(GO:0002513)
0.1 0.1 GO:0045589 regulation of regulatory T cell differentiation(GO:0045589)
0.1 0.4 GO:0072033 renal vesicle formation(GO:0072033)
0.1 0.4 GO:0010447 response to acidic pH(GO:0010447)
0.1 0.4 GO:0051988 regulation of attachment of spindle microtubules to kinetochore(GO:0051988)
0.1 1.0 GO:0007172 signal complex assembly(GO:0007172)
0.1 0.5 GO:0046642 negative regulation of alpha-beta T cell proliferation(GO:0046642)
0.1 0.4 GO:0010572 positive regulation of platelet activation(GO:0010572)
0.1 0.1 GO:0050862 positive regulation of T cell receptor signaling pathway(GO:0050862)
0.1 0.5 GO:0007042 lysosomal lumen acidification(GO:0007042) regulation of lysosomal lumen pH(GO:0035751)
0.1 0.3 GO:0090292 nuclear matrix organization(GO:0043578) nuclear matrix anchoring at nuclear membrane(GO:0090292)
0.1 0.3 GO:0046137 negative regulation of calcidiol 1-monooxygenase activity(GO:0010956) negative regulation of vitamin D biosynthetic process(GO:0010957) negative regulation of vitamin metabolic process(GO:0046137)
0.1 0.6 GO:0007256 activation of JNKK activity(GO:0007256)
0.1 0.4 GO:0002858 natural killer cell mediated cytotoxicity directed against tumor cell target(GO:0002420) natural killer cell mediated immune response to tumor cell(GO:0002423) regulation of natural killer cell mediated immune response to tumor cell(GO:0002855) positive regulation of natural killer cell mediated immune response to tumor cell(GO:0002857) regulation of natural killer cell mediated cytotoxicity directed against tumor cell target(GO:0002858) positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target(GO:0002860)
0.1 0.4 GO:0010592 positive regulation of lamellipodium assembly(GO:0010592) positive regulation of lamellipodium organization(GO:1902745)
0.1 1.2 GO:0043368 positive T cell selection(GO:0043368)
0.1 0.5 GO:0045898 regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045898)
0.1 0.3 GO:0045056 transcytosis(GO:0045056)
0.1 0.1 GO:0032693 negative regulation of interleukin-10 production(GO:0032693)
0.1 0.3 GO:0045722 positive regulation of gluconeogenesis(GO:0045722)
0.1 0.1 GO:0002677 negative regulation of chronic inflammatory response(GO:0002677)
0.1 0.2 GO:0071481 cellular response to X-ray(GO:0071481)
0.1 0.2 GO:0002032 desensitization of G-protein coupled receptor protein signaling pathway by arrestin(GO:0002032)
0.1 0.3 GO:0060605 tube lumen cavitation(GO:0060605) salivary gland cavitation(GO:0060662)
0.1 0.3 GO:0045341 MHC class I biosynthetic process(GO:0045341) regulation of MHC class I biosynthetic process(GO:0045343)
0.1 0.4 GO:0070584 mitochondrion morphogenesis(GO:0070584)
0.1 1.1 GO:0030260 entry into host cell(GO:0030260) entry into host(GO:0044409) entry into cell of other organism involved in symbiotic interaction(GO:0051806) entry into other organism involved in symbiotic interaction(GO:0051828)
0.1 0.2 GO:0042091 interleukin-10 biosynthetic process(GO:0042091) regulation of interleukin-10 biosynthetic process(GO:0045074)
0.1 0.8 GO:0032653 regulation of interleukin-10 production(GO:0032653)
0.1 0.2 GO:0001831 trophectodermal cellular morphogenesis(GO:0001831)
0.1 0.2 GO:0001766 membrane raft polarization(GO:0001766) membrane raft distribution(GO:0031580)
0.1 0.3 GO:0033688 regulation of osteoblast proliferation(GO:0033688)
0.1 0.1 GO:0002693 regulation of cellular extravasation(GO:0002691) positive regulation of cellular extravasation(GO:0002693)
0.1 1.9 GO:0050690 regulation of defense response to virus by virus(GO:0050690)
0.1 0.2 GO:0009048 dosage compensation by inactivation of X chromosome(GO:0009048)
0.1 0.5 GO:0060123 regulation of growth hormone secretion(GO:0060123)
0.1 0.2 GO:0070777 D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
0.1 0.7 GO:0000381 regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.1 0.3 GO:0007095 mitotic G2 DNA damage checkpoint(GO:0007095)
0.1 0.2 GO:0048388 endosomal lumen acidification(GO:0048388)
0.1 0.1 GO:0006681 galactosylceramide metabolic process(GO:0006681)
0.1 0.4 GO:0019987 obsolete negative regulation of anti-apoptosis(GO:0019987)
0.1 0.1 GO:0042271 susceptibility to natural killer cell mediated cytotoxicity(GO:0042271)
0.1 0.1 GO:0002679 respiratory burst involved in defense response(GO:0002679)
0.1 0.1 GO:0052033 pathogen-associated molecular pattern dependent induction by symbiont of host innate immune response(GO:0052033) positive regulation by symbiont of host innate immune response(GO:0052166) modulation by symbiont of host innate immune response(GO:0052167) pathogen-associated molecular pattern dependent modulation by symbiont of host innate immune response(GO:0052169) pathogen-associated molecular pattern dependent induction by organism of innate immune response of other organism involved in symbiotic interaction(GO:0052257) positive regulation by organism of innate immune response in other organism involved in symbiotic interaction(GO:0052305) modulation by organism of innate immune response in other organism involved in symbiotic interaction(GO:0052306) pathogen-associated molecular pattern dependent modulation by organism of innate immune response in other organism involved in symbiotic interaction(GO:0052308)
0.1 0.3 GO:0022614 membrane to membrane docking(GO:0022614)
0.1 0.2 GO:0002313 mature B cell differentiation involved in immune response(GO:0002313)
0.1 0.2 GO:0035405 histone-threonine phosphorylation(GO:0035405)
0.1 0.1 GO:0034587 piRNA metabolic process(GO:0034587)
0.1 0.3 GO:0007023 post-chaperonin tubulin folding pathway(GO:0007023)
0.1 0.2 GO:0034626 fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.1 0.3 GO:0042023 regulation of DNA endoreduplication(GO:0032875) negative regulation of DNA endoreduplication(GO:0032876) DNA endoreduplication(GO:0042023)
0.1 0.2 GO:0043320 natural killer cell activation involved in immune response(GO:0002323) natural killer cell degranulation(GO:0043320)
0.1 0.2 GO:0002523 leukocyte migration involved in inflammatory response(GO:0002523)
0.1 0.2 GO:1901985 positive regulation of histone acetylation(GO:0035066) positive regulation of protein acetylation(GO:1901985) positive regulation of peptidyl-lysine acetylation(GO:2000758)
0.1 0.1 GO:0002335 mature B cell differentiation(GO:0002335)
0.1 0.9 GO:0016578 histone deubiquitination(GO:0016578)
0.1 0.1 GO:0090286 cytoskeletal anchoring at nuclear membrane(GO:0090286)
0.1 0.4 GO:0045910 negative regulation of DNA recombination(GO:0045910)
0.1 0.1 GO:0052555 positive regulation by organism of immune response of other organism involved in symbiotic interaction(GO:0052555) positive regulation by symbiont of host immune response(GO:0052556)
0.1 0.2 GO:0046476 glycosylceramide biosynthetic process(GO:0046476)
0.1 0.6 GO:0006301 postreplication repair(GO:0006301)
0.1 0.2 GO:0017182 peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183)
0.1 0.4 GO:0051491 positive regulation of filopodium assembly(GO:0051491)
0.1 0.3 GO:0048096 chromatin-mediated maintenance of transcription(GO:0048096)
0.1 0.3 GO:2001021 negative regulation of response to DNA damage stimulus(GO:2001021)
0.1 0.3 GO:0010452 histone H3-K36 methylation(GO:0010452)
0.1 0.1 GO:0007571 age-dependent response to oxidative stress(GO:0001306) age-dependent general metabolic decline(GO:0007571)
0.1 0.2 GO:0006772 thiamine metabolic process(GO:0006772)
0.1 0.3 GO:0002327 immature B cell differentiation(GO:0002327) pre-B cell differentiation(GO:0002329)
0.1 0.2 GO:0018076 N-terminal peptidyl-lysine acetylation(GO:0018076)
0.1 0.2 GO:0000301 retrograde transport, vesicle recycling within Golgi(GO:0000301)
0.1 0.2 GO:0010536 regulation of activation of Janus kinase activity(GO:0010533) positive regulation of activation of Janus kinase activity(GO:0010536)
0.1 0.2 GO:0006422 aspartyl-tRNA aminoacylation(GO:0006422)
0.1 0.2 GO:0051708 intracellular transport of viral protein in host cell(GO:0019060) symbiont intracellular protein transport in host(GO:0030581) regulation by virus of viral protein levels in host cell(GO:0046719) intracellular protein transport in other organism involved in symbiotic interaction(GO:0051708)
0.1 0.4 GO:0015671 oxygen transport(GO:0015671)
0.1 3.3 GO:0050852 T cell receptor signaling pathway(GO:0050852)
0.1 0.2 GO:0072526 pyridine-containing compound catabolic process(GO:0072526)
0.1 0.2 GO:0006167 AMP biosynthetic process(GO:0006167)
0.1 0.4 GO:0008608 attachment of spindle microtubules to kinetochore(GO:0008608)
0.1 0.2 GO:0000733 DNA strand renaturation(GO:0000733)
0.1 0.1 GO:0051489 regulation of filopodium assembly(GO:0051489)
0.0 0.6 GO:0043666 regulation of phosphoprotein phosphatase activity(GO:0043666)
0.0 0.1 GO:0046049 UMP biosynthetic process(GO:0006222) pyrimidine ribonucleoside monophosphate metabolic process(GO:0009173) pyrimidine ribonucleoside monophosphate biosynthetic process(GO:0009174) UMP metabolic process(GO:0046049)
0.0 0.1 GO:0002220 innate immune response activating cell surface receptor signaling pathway(GO:0002220)
0.0 0.1 GO:0001672 regulation of chromatin assembly or disassembly(GO:0001672)
0.0 0.2 GO:0033169 histone H3-K9 demethylation(GO:0033169)
0.0 0.2 GO:0090322 regulation of superoxide metabolic process(GO:0090322)
0.0 0.0 GO:0010310 regulation of hydrogen peroxide metabolic process(GO:0010310)
0.0 1.3 GO:0042059 negative regulation of epidermal growth factor receptor signaling pathway(GO:0042059) negative regulation of ERBB signaling pathway(GO:1901185)
0.0 0.2 GO:0048488 synaptic vesicle recycling(GO:0036465) synaptic vesicle endocytosis(GO:0048488) clathrin-mediated endocytosis(GO:0072583)
0.0 0.0 GO:0033622 integrin activation(GO:0033622)
0.0 0.1 GO:0043951 negative regulation of cAMP-mediated signaling(GO:0043951)
0.0 0.2 GO:0031936 negative regulation of chromatin silencing(GO:0031936)
0.0 0.1 GO:0043653 mitochondrial fragmentation involved in apoptotic process(GO:0043653)
0.0 0.1 GO:0045875 negative regulation of sister chromatid cohesion(GO:0045875)
0.0 0.2 GO:0014742 positive regulation of cardiac muscle hypertrophy(GO:0010613) positive regulation of muscle hypertrophy(GO:0014742)
0.0 0.0 GO:0040009 regulation of growth rate(GO:0040009)
0.0 0.0 GO:0033632 regulation of cell-cell adhesion mediated by integrin(GO:0033632)
0.0 0.1 GO:0006667 sphinganine metabolic process(GO:0006667)
0.0 0.1 GO:0009215 purine deoxyribonucleoside triphosphate metabolic process(GO:0009215)
0.0 0.3 GO:0031529 ruffle organization(GO:0031529)
0.0 0.3 GO:0006491 N-glycan processing(GO:0006491)
0.0 0.2 GO:0000183 chromatin silencing at rDNA(GO:0000183)
0.0 0.1 GO:1901522 positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus(GO:1901522)
0.0 0.2 GO:0030910 olfactory placode formation(GO:0030910) olfactory placode development(GO:0071698) olfactory placode morphogenesis(GO:0071699)
0.0 0.1 GO:0001574 ganglioside biosynthetic process(GO:0001574)
0.0 0.1 GO:0009129 pyrimidine nucleoside monophosphate metabolic process(GO:0009129)
0.0 0.2 GO:0006048 UDP-N-acetylglucosamine biosynthetic process(GO:0006048)
0.0 0.1 GO:0006686 sphingomyelin biosynthetic process(GO:0006686)
0.0 0.1 GO:0043276 anoikis(GO:0043276)
0.0 0.1 GO:0045292 mRNA cis splicing, via spliceosome(GO:0045292)
0.0 0.2 GO:0043353 enucleate erythrocyte differentiation(GO:0043353)
0.0 0.2 GO:0042989 sequestering of actin monomers(GO:0042989)
0.0 0.3 GO:0032703 negative regulation of interleukin-2 production(GO:0032703)
0.0 0.3 GO:0006030 chitin metabolic process(GO:0006030) chitin catabolic process(GO:0006032)
0.0 0.1 GO:0007100 mitotic centrosome separation(GO:0007100)
0.0 0.2 GO:0019883 antigen processing and presentation of endogenous antigen(GO:0019883)
0.0 0.4 GO:0045022 early endosome to late endosome transport(GO:0045022) vesicle-mediated transport between endosomal compartments(GO:0098927)
0.0 0.1 GO:0045793 positive regulation of cell size(GO:0045793)
0.0 0.1 GO:0002902 regulation of B cell apoptotic process(GO:0002902) negative regulation of B cell apoptotic process(GO:0002903)
0.0 0.1 GO:0045603 positive regulation of endothelial cell differentiation(GO:0045603)
0.0 0.1 GO:0002468 dendritic cell antigen processing and presentation(GO:0002468) regulation of dendritic cell antigen processing and presentation(GO:0002604)
0.0 0.2 GO:0045003 DNA recombinase assembly(GO:0000730) double-strand break repair via synthesis-dependent strand annealing(GO:0045003)
0.0 0.2 GO:0045954 positive regulation of natural killer cell mediated immunity(GO:0002717) positive regulation of natural killer cell mediated cytotoxicity(GO:0045954)
0.0 0.0 GO:0051103 DNA ligation involved in DNA repair(GO:0051103)
0.0 0.1 GO:0060287 epithelial cilium movement(GO:0003351) epithelial cilium movement involved in determination of left/right asymmetry(GO:0060287)
0.0 0.2 GO:0048013 ephrin receptor signaling pathway(GO:0048013)
0.0 0.2 GO:0060292 long term synaptic depression(GO:0060292)
0.0 0.1 GO:0043568 positive regulation of insulin-like growth factor receptor signaling pathway(GO:0043568)
0.0 0.2 GO:0043984 histone H4-K16 acetylation(GO:0043984)
0.0 0.1 GO:0018094 protein polyglycylation(GO:0018094)
0.0 0.1 GO:0016572 histone phosphorylation(GO:0016572)
0.0 0.0 GO:0046633 alpha-beta T cell proliferation(GO:0046633)
0.0 0.1 GO:0015801 aromatic amino acid transport(GO:0015801)
0.0 0.2 GO:0006685 sphingomyelin catabolic process(GO:0006685)
0.0 0.1 GO:0006701 progesterone biosynthetic process(GO:0006701)
0.0 0.0 GO:0002507 tolerance induction(GO:0002507)
0.0 0.6 GO:0043124 negative regulation of I-kappaB kinase/NF-kappaB signaling(GO:0043124)
0.0 0.1 GO:0001821 histamine secretion(GO:0001821)
0.0 0.0 GO:0003402 planar cell polarity pathway involved in axis elongation(GO:0003402)
0.0 0.0 GO:0045066 regulatory T cell differentiation(GO:0045066)
0.0 0.2 GO:0010832 negative regulation of myotube differentiation(GO:0010832)
0.0 0.0 GO:0051461 corticotropin secretion(GO:0051458) regulation of corticotropin secretion(GO:0051459) positive regulation of corticotropin secretion(GO:0051461)
0.0 0.1 GO:0002430 complement receptor mediated signaling pathway(GO:0002430)
0.0 0.1 GO:0019509 L-methionine biosynthetic process from methylthioadenosine(GO:0019509)
0.0 0.1 GO:0032926 negative regulation of activin receptor signaling pathway(GO:0032926)
0.0 0.1 GO:0009103 lipopolysaccharide biosynthetic process(GO:0009103)
0.0 0.1 GO:0070934 CRD-mediated mRNA stabilization(GO:0070934)
0.0 0.1 GO:0006922 obsolete cleavage of lamin involved in execution phase of apoptosis(GO:0006922)
0.0 0.2 GO:0043508 negative regulation of JUN kinase activity(GO:0043508)
0.0 0.1 GO:0048240 sperm capacitation(GO:0048240)
0.0 0.1 GO:0060972 left/right pattern formation(GO:0060972)
0.0 0.3 GO:0003084 positive regulation of systemic arterial blood pressure(GO:0003084)
0.0 0.3 GO:0031146 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process(GO:0031146)
0.0 0.0 GO:0042362 fat-soluble vitamin biosynthetic process(GO:0042362)
0.0 0.2 GO:0021692 cerebellar Purkinje cell layer morphogenesis(GO:0021692) cerebellar Purkinje cell layer formation(GO:0021694) cerebellar Purkinje cell differentiation(GO:0021702)
0.0 0.1 GO:0034755 iron ion transmembrane transport(GO:0034755)
0.0 0.1 GO:0006999 nuclear pore organization(GO:0006999)
0.0 0.4 GO:0043489 RNA stabilization(GO:0043489) mRNA stabilization(GO:0048255)
0.0 0.1 GO:0007064 mitotic sister chromatid cohesion(GO:0007064)
0.0 0.1 GO:0009189 deoxyribonucleoside diphosphate biosynthetic process(GO:0009189)
0.0 0.1 GO:0060049 regulation of protein glycosylation(GO:0060049)
0.0 0.1 GO:1901534 positive regulation of megakaryocyte differentiation(GO:0045654) positive regulation of hematopoietic progenitor cell differentiation(GO:1901534)
0.0 0.1 GO:0060586 multicellular organismal iron ion homeostasis(GO:0060586)
0.0 0.1 GO:2000114 regulation of establishment of cell polarity(GO:2000114)
0.0 0.1 GO:0045906 negative regulation of vasoconstriction(GO:0045906)
0.0 0.1 GO:0017014 protein nitrosylation(GO:0017014) peptidyl-cysteine S-nitrosylation(GO:0018119)
0.0 0.1 GO:0010508 positive regulation of autophagy(GO:0010508)
0.0 0.1 GO:0070682 proteasome regulatory particle assembly(GO:0070682)
0.0 0.1 GO:0035588 adenosine receptor signaling pathway(GO:0001973) G-protein coupled purinergic receptor signaling pathway(GO:0035588)
0.0 0.1 GO:0071428 rRNA-containing ribonucleoprotein complex export from nucleus(GO:0071428)
0.0 0.1 GO:0034421 post-translational protein acetylation(GO:0034421)
0.0 0.1 GO:0022030 cerebral cortex radial glia guided migration(GO:0021801) layer formation in cerebral cortex(GO:0021819) telencephalon glial cell migration(GO:0022030)
0.0 0.1 GO:0034139 regulation of toll-like receptor 3 signaling pathway(GO:0034139)
0.0 0.1 GO:0001302 replicative cell aging(GO:0001302)
0.0 0.1 GO:0045618 positive regulation of keratinocyte differentiation(GO:0045618)
0.0 0.1 GO:0006011 UDP-glucose metabolic process(GO:0006011)
0.0 0.0 GO:0032959 inositol trisphosphate biosynthetic process(GO:0032959)
0.0 0.1 GO:0021604 cranial nerve structural organization(GO:0021604) facial nerve morphogenesis(GO:0021610) facial nerve structural organization(GO:0021612)
0.0 0.1 GO:0072531 pyrimidine-containing compound transmembrane transport(GO:0072531)
0.0 0.6 GO:0000289 nuclear-transcribed mRNA poly(A) tail shortening(GO:0000289)
0.0 0.0 GO:0042501 serine phosphorylation of STAT protein(GO:0042501)
0.0 0.1 GO:0060745 mammary gland branching involved in pregnancy(GO:0060745)
0.0 0.1 GO:0032543 mitochondrial translation(GO:0032543)
0.0 0.1 GO:0016556 mRNA modification(GO:0016556)
0.0 0.1 GO:0043137 DNA replication, Okazaki fragment processing(GO:0033567) DNA replication, removal of RNA primer(GO:0043137)
0.0 0.1 GO:0006047 UDP-N-acetylglucosamine metabolic process(GO:0006047)
0.0 0.1 GO:0006556 S-adenosylmethionine biosynthetic process(GO:0006556)
0.0 0.0 GO:0010922 positive regulation of phosphatase activity(GO:0010922)
0.0 0.4 GO:0051865 protein autoubiquitination(GO:0051865)
0.0 0.2 GO:0043487 regulation of RNA stability(GO:0043487)
0.0 0.1 GO:0006515 misfolded or incompletely synthesized protein catabolic process(GO:0006515)
0.0 0.2 GO:0014037 Schwann cell differentiation(GO:0014037)
0.0 0.2 GO:0008635 activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c(GO:0008635)
0.0 0.1 GO:0006474 N-terminal protein amino acid acetylation(GO:0006474)
0.0 0.1 GO:0048318 axial mesoderm development(GO:0048318)
0.0 0.3 GO:0051568 histone H3-K4 methylation(GO:0051568)
0.0 0.1 GO:0015722 canalicular bile acid transport(GO:0015722)
0.0 0.1 GO:1903077 negative regulation of establishment of protein localization to plasma membrane(GO:0090005) negative regulation of protein localization to plasma membrane(GO:1903077) negative regulation of protein localization to cell periphery(GO:1904376)
0.0 0.1 GO:0006269 DNA replication, synthesis of RNA primer(GO:0006269)
0.0 0.1 GO:0032528 microvillus assembly(GO:0030033) microvillus organization(GO:0032528)
0.0 0.9 GO:0070646 protein modification by small protein removal(GO:0070646)
0.0 0.0 GO:0006154 adenosine catabolic process(GO:0006154)
0.0 0.1 GO:0006658 phosphatidylserine metabolic process(GO:0006658)
0.0 0.1 GO:0051593 response to folic acid(GO:0051593)
0.0 0.1 GO:0034314 Arp2/3 complex-mediated actin nucleation(GO:0034314)
0.0 0.1 GO:0000491 small nucleolar ribonucleoprotein complex assembly(GO:0000491) box C/D snoRNP assembly(GO:0000492)
0.0 0.2 GO:0030224 monocyte differentiation(GO:0030224)
0.0 0.0 GO:0070244 negative regulation of thymocyte apoptotic process(GO:0070244)
0.0 0.1 GO:0048268 clathrin coat assembly(GO:0048268)
0.0 0.0 GO:0032494 response to peptidoglycan(GO:0032494)
0.0 0.0 GO:0070664 negative regulation of leukocyte proliferation(GO:0070664)
0.0 0.1 GO:0033079 immature T cell proliferation(GO:0033079) immature T cell proliferation in thymus(GO:0033080)
0.0 0.1 GO:0060023 soft palate development(GO:0060023)
0.0 0.0 GO:0031297 replication fork processing(GO:0031297)
0.0 0.0 GO:0072385 minus-end-directed organelle transport along microtubule(GO:0072385)
0.0 0.1 GO:1904181 positive regulation of mitochondrial depolarization(GO:0051901) positive regulation of membrane depolarization(GO:1904181)
0.0 0.0 GO:0010831 positive regulation of myotube differentiation(GO:0010831)
0.0 0.1 GO:0042098 T cell proliferation(GO:0042098)
0.0 0.1 GO:0032119 sequestering of zinc ion(GO:0032119)
0.0 0.1 GO:0000012 single strand break repair(GO:0000012)
0.0 0.0 GO:0032495 response to muramyl dipeptide(GO:0032495)
0.0 0.1 GO:0048714 positive regulation of oligodendrocyte differentiation(GO:0048714)
0.0 0.0 GO:0042748 circadian sleep/wake cycle, non-REM sleep(GO:0042748) regulation of circadian sleep/wake cycle, non-REM sleep(GO:0045188)
0.0 0.1 GO:0008214 protein demethylation(GO:0006482) protein dealkylation(GO:0008214)
0.0 0.3 GO:0071044 histone mRNA catabolic process(GO:0071044)
0.0 0.1 GO:0060017 parathyroid gland development(GO:0060017)
0.0 0.1 GO:0032506 cytokinetic process(GO:0032506)
0.0 0.1 GO:0008340 determination of adult lifespan(GO:0008340)
0.0 0.0 GO:0045356 positive regulation of interferon-alpha biosynthetic process(GO:0045356)
0.0 0.0 GO:0060433 bronchus development(GO:0060433)
0.0 0.4 GO:0006284 base-excision repair(GO:0006284)
0.0 0.1 GO:0010919 regulation of inositol phosphate biosynthetic process(GO:0010919) positive regulation of inositol phosphate biosynthetic process(GO:0060732)
0.0 0.0 GO:0040016 embryonic cleavage(GO:0040016)
0.0 0.2 GO:0016045 detection of bacterium(GO:0016045)
0.0 0.3 GO:0015893 drug transport(GO:0015893)
0.0 0.2 GO:0006379 mRNA cleavage(GO:0006379)
0.0 0.3 GO:0006297 nucleotide-excision repair, DNA gap filling(GO:0006297)
0.0 0.4 GO:0006997 nucleus organization(GO:0006997)
0.0 0.1 GO:0051451 myoblast migration(GO:0051451)
0.0 0.1 GO:0050710 negative regulation of cytokine secretion(GO:0050710)
0.0 0.2 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.0 0.2 GO:0007020 microtubule nucleation(GO:0007020)
0.0 1.0 GO:0006921 cellular component disassembly involved in execution phase of apoptosis(GO:0006921) execution phase of apoptosis(GO:0097194)
0.0 0.1 GO:0048024 regulation of mRNA splicing, via spliceosome(GO:0048024)
0.0 0.1 GO:0006089 lactate metabolic process(GO:0006089)
0.0 0.1 GO:0009786 regulation of asymmetric cell division(GO:0009786)
0.0 0.1 GO:0090047 obsolete positive regulation of transcription regulator activity(GO:0090047)
0.0 0.1 GO:0042435 indole-containing compound biosynthetic process(GO:0042435)
0.0 0.1 GO:0048625 myoblast fate commitment(GO:0048625)
0.0 0.0 GO:0030889 negative regulation of B cell proliferation(GO:0030889)
0.0 0.5 GO:0000245 spliceosomal complex assembly(GO:0000245)
0.0 0.1 GO:0046831 regulation of RNA export from nucleus(GO:0046831)
0.0 0.1 GO:0007352 zygotic specification of dorsal/ventral axis(GO:0007352)
0.0 0.4 GO:0006071 glycerol metabolic process(GO:0006071)
0.0 0.2 GO:0031163 iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163)
0.0 0.1 GO:0002925 positive regulation of humoral immune response mediated by circulating immunoglobulin(GO:0002925)
0.0 0.4 GO:0006611 protein export from nucleus(GO:0006611)
0.0 0.1 GO:0001782 B cell homeostasis(GO:0001782)
0.0 0.1 GO:0044273 sulfur compound catabolic process(GO:0044273)
0.0 0.1 GO:0033261 obsolete regulation of S phase(GO:0033261)
0.0 0.7 GO:0007193 adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway(GO:0007193)
0.0 0.0 GO:0048304 positive regulation of isotype switching to IgG isotypes(GO:0048304)
0.0 0.6 GO:0006888 ER to Golgi vesicle-mediated transport(GO:0006888)
0.0 0.1 GO:0034453 microtubule anchoring(GO:0034453)
0.0 0.1 GO:0047484 regulation of response to osmotic stress(GO:0047484)
0.0 0.0 GO:0044803 multi-organism membrane organization(GO:0044803)
0.0 0.1 GO:0002063 chondrocyte development(GO:0002063)
0.0 0.5 GO:0001906 cell killing(GO:0001906)
0.0 0.1 GO:0006622 protein targeting to lysosome(GO:0006622) protein targeting to vacuole(GO:0006623) protein localization to lysosome(GO:0061462) protein localization to vacuole(GO:0072665) establishment of protein localization to vacuole(GO:0072666)
0.0 0.1 GO:0006420 arginyl-tRNA aminoacylation(GO:0006420)
0.0 0.1 GO:0009301 snRNA transcription(GO:0009301)
0.0 0.1 GO:0045084 positive regulation of interleukin-12 biosynthetic process(GO:0045084)
0.0 1.3 GO:0018279 peptidyl-asparagine modification(GO:0018196) protein N-linked glycosylation via asparagine(GO:0018279)
0.0 0.0 GO:0061154 endothelial tube morphogenesis(GO:0061154)
0.0 0.2 GO:0021516 dorsal spinal cord development(GO:0021516)
0.0 0.1 GO:0002921 negative regulation of humoral immune response(GO:0002921) negative regulation of complement activation(GO:0045916) negative regulation of protein activation cascade(GO:2000258)
0.0 0.0 GO:0044266 regulation of renal output by angiotensin(GO:0002019) multicellular organismal protein catabolic process(GO:0044254) protein digestion(GO:0044256) multicellular organismal macromolecule catabolic process(GO:0044266) multicellular organismal protein metabolic process(GO:0044268)
0.0 0.0 GO:0031058 positive regulation of histone modification(GO:0031058)
0.0 0.0 GO:0046502 uroporphyrinogen III metabolic process(GO:0046502)
0.0 0.0 GO:0001832 blastocyst growth(GO:0001832)
0.0 0.1 GO:0060040 retinal bipolar neuron differentiation(GO:0060040)
0.0 0.0 GO:0043457 regulation of cellular respiration(GO:0043457)
0.0 0.1 GO:0071501 SREBP signaling pathway(GO:0032933) cellular response to sterol depletion(GO:0071501)
0.0 0.3 GO:0007339 binding of sperm to zona pellucida(GO:0007339)
0.0 0.1 GO:0042994 cytoplasmic sequestering of transcription factor(GO:0042994)
0.0 0.0 GO:0021548 pons development(GO:0021548)
0.0 0.1 GO:0002138 retinoic acid biosynthetic process(GO:0002138) diterpenoid biosynthetic process(GO:0016102)
0.0 0.2 GO:0015804 neutral amino acid transport(GO:0015804)
0.0 0.1 GO:0006303 double-strand break repair via nonhomologous end joining(GO:0006303)
0.0 0.2 GO:0043252 sodium-independent organic anion transport(GO:0043252)
0.0 0.1 GO:0006356 regulation of transcription from RNA polymerase I promoter(GO:0006356)
0.0 0.1 GO:0019255 glucose 1-phosphate metabolic process(GO:0019255)
0.0 0.1 GO:0008295 spermidine biosynthetic process(GO:0008295)
0.0 0.0 GO:0048539 bone marrow development(GO:0048539)
0.0 0.1 GO:0006900 membrane budding(GO:0006900) vesicle coating(GO:0006901) single-organism membrane budding(GO:1902591)
0.0 0.1 GO:0046477 glycoside metabolic process(GO:0016137) glycoside catabolic process(GO:0016139) glycosylceramide catabolic process(GO:0046477)
0.0 0.0 GO:0051938 L-glutamate import(GO:0051938)
0.0 0.0 GO:0033008 positive regulation of myeloid leukocyte mediated immunity(GO:0002888) positive regulation of mast cell activation involved in immune response(GO:0033008) positive regulation of leukocyte degranulation(GO:0043302) positive regulation of mast cell degranulation(GO:0043306)
0.0 0.2 GO:0002286 T cell activation involved in immune response(GO:0002286)
0.0 0.4 GO:0032480 negative regulation of type I interferon production(GO:0032480)
0.0 0.0 GO:0034201 response to oleic acid(GO:0034201)
0.0 0.1 GO:0006465 signal peptide processing(GO:0006465)
0.0 0.1 GO:0046501 protoporphyrinogen IX metabolic process(GO:0046501)
0.0 0.0 GO:0034122 negative regulation of toll-like receptor signaling pathway(GO:0034122)
0.0 0.0 GO:0048199 vesicle targeting, to, from or within Golgi(GO:0048199)
0.0 0.1 GO:0045046 protein import into peroxisome membrane(GO:0045046)
0.0 0.0 GO:0060744 thelarche(GO:0042695) development of secondary sexual characteristics(GO:0045136) development of secondary female sexual characteristics(GO:0046543) mammary gland branching involved in thelarche(GO:0060744)
0.0 0.1 GO:0007021 tubulin complex assembly(GO:0007021)
0.0 0.4 GO:0033572 ferric iron transport(GO:0015682) transferrin transport(GO:0033572) trivalent inorganic cation transport(GO:0072512)
0.0 0.0 GO:1900619 acetylcholine metabolic process(GO:0008291) acetate ester metabolic process(GO:1900619)
0.0 0.2 GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)
0.0 0.4 GO:0046847 filopodium assembly(GO:0046847)
0.0 0.1 GO:0022027 interkinetic nuclear migration(GO:0022027)
0.0 0.0 GO:0072205 collecting duct development(GO:0072044) metanephric collecting duct development(GO:0072205)
0.0 0.1 GO:0045116 protein neddylation(GO:0045116)
0.0 0.0 GO:0031223 auditory behavior(GO:0031223)
0.0 0.0 GO:0072178 nephric duct morphogenesis(GO:0072178)
0.0 0.2 GO:0007052 mitotic spindle organization(GO:0007052)
0.0 0.1 GO:0019043 establishment of viral latency(GO:0019043) establishment of integrated proviral latency(GO:0075713)
0.0 0.1 GO:1903078 positive regulation of establishment of protein localization to plasma membrane(GO:0090004) positive regulation of protein localization to plasma membrane(GO:1903078) positive regulation of protein localization to cell periphery(GO:1904377)
0.0 0.0 GO:0045005 DNA-dependent DNA replication maintenance of fidelity(GO:0045005)
0.0 0.0 GO:0045117 azole transport(GO:0045117)
0.0 0.0 GO:0051386 regulation of neurotrophin TRK receptor signaling pathway(GO:0051386)
0.0 0.1 GO:0006657 CDP-choline pathway(GO:0006657)
0.0 0.0 GO:0032109 positive regulation of response to extracellular stimulus(GO:0032106) positive regulation of response to nutrient levels(GO:0032109)
0.0 0.2 GO:0045730 respiratory burst(GO:0045730)
0.0 0.0 GO:0006007 glucose catabolic process(GO:0006007)
0.0 0.1 GO:0006198 cAMP catabolic process(GO:0006198)
0.0 0.1 GO:0006824 cobalt ion transport(GO:0006824)
0.0 0.2 GO:0016180 snRNA processing(GO:0016180)
0.0 0.1 GO:0006378 mRNA polyadenylation(GO:0006378)
0.0 0.0 GO:0002125 maternal aggressive behavior(GO:0002125)
0.0 0.2 GO:0033138 positive regulation of peptidyl-serine phosphorylation(GO:0033138)
0.0 0.0 GO:0042109 lymphotoxin A production(GO:0032641) lymphotoxin A biosynthetic process(GO:0042109)
0.0 0.1 GO:0070528 protein kinase C signaling(GO:0070528)
0.0 0.0 GO:0045990 carbon catabolite regulation of transcription(GO:0045990) regulation of transcription by glucose(GO:0046015)
0.0 0.0 GO:0001820 serotonin secretion(GO:0001820)
0.0 0.2 GO:0014823 response to activity(GO:0014823)
0.0 0.1 GO:0042403 thyroid hormone metabolic process(GO:0042403)
0.0 0.0 GO:0046607 positive regulation of centrosome cycle(GO:0046607)
0.0 0.0 GO:0042984 amyloid precursor protein biosynthetic process(GO:0042983) regulation of amyloid precursor protein biosynthetic process(GO:0042984)
0.0 0.0 GO:0032667 interleukin-23 production(GO:0032627) regulation of interleukin-23 production(GO:0032667)
0.0 0.2 GO:0060334 regulation of response to interferon-gamma(GO:0060330) regulation of interferon-gamma-mediated signaling pathway(GO:0060334)
0.0 0.0 GO:0002069 columnar/cuboidal epithelial cell maturation(GO:0002069)
0.0 0.0 GO:0048537 mucosal-associated lymphoid tissue development(GO:0048537)
0.0 0.0 GO:0015864 pyrimidine nucleoside transport(GO:0015864)
0.0 0.3 GO:0007257 activation of JUN kinase activity(GO:0007257)
0.0 0.0 GO:0046549 retinal cone cell differentiation(GO:0042670) retinal cone cell development(GO:0046549)
0.0 0.0 GO:0061028 establishment of endothelial barrier(GO:0061028)
0.0 0.1 GO:0018026 peptidyl-lysine monomethylation(GO:0018026)
0.0 0.0 GO:0051573 regulation of histone H3-K9 methylation(GO:0051570) negative regulation of histone H3-K9 methylation(GO:0051573)
0.0 0.3 GO:0021549 cerebellum development(GO:0021549) metencephalon development(GO:0022037)
0.0 0.0 GO:1904358 positive regulation of telomere maintenance via telomerase(GO:0032212) positive regulation of telomere maintenance via telomere lengthening(GO:1904358)
0.0 0.1 GO:0031572 G2 DNA damage checkpoint(GO:0031572)
0.0 0.0 GO:0017121 phospholipid scrambling(GO:0017121)
0.0 0.1 GO:0015851 nucleobase transport(GO:0015851)
0.0 0.0 GO:0045901 translational frameshifting(GO:0006452) positive regulation of translational elongation(GO:0045901) positive regulation of translational termination(GO:0045905)
0.0 0.0 GO:0046101 hypoxanthine biosynthetic process(GO:0046101)
0.0 0.0 GO:0031057 negative regulation of histone modification(GO:0031057) negative regulation of histone acetylation(GO:0035067) negative regulation of protein acetylation(GO:1901984) negative regulation of peptidyl-lysine acetylation(GO:2000757)
0.0 0.3 GO:0034724 DNA replication-independent nucleosome assembly(GO:0006336) CENP-A containing nucleosome assembly(GO:0034080) DNA replication-independent nucleosome organization(GO:0034724) CENP-A containing chromatin organization(GO:0061641)
0.0 0.0 GO:0009822 alkaloid catabolic process(GO:0009822)
0.0 0.1 GO:0006538 glutamate catabolic process(GO:0006538)
0.0 0.0 GO:0002438 acute inflammatory response to antigenic stimulus(GO:0002438)
0.0 0.1 GO:0015074 DNA integration(GO:0015074)
0.0 0.0 GO:0010989 negative regulation of low-density lipoprotein particle clearance(GO:0010989)
0.0 0.5 GO:0034112 positive regulation of homotypic cell-cell adhesion(GO:0034112)
0.0 0.0 GO:0045601 regulation of endothelial cell differentiation(GO:0045601)
0.0 0.0 GO:0008298 intracellular mRNA localization(GO:0008298)
0.0 0.0 GO:0032527 protein exit from endoplasmic reticulum(GO:0032527)
0.0 0.2 GO:0022616 DNA strand elongation(GO:0022616)
0.0 0.2 GO:0090174 organelle membrane fusion(GO:0090174)
0.0 0.1 GO:0000303 response to superoxide(GO:0000303)
0.0 0.0 GO:0046968 peptide antigen transport(GO:0046968)
0.0 0.0 GO:0050832 defense response to fungus(GO:0050832)
0.0 0.0 GO:0043490 malate-aspartate shuttle(GO:0043490)
0.0 0.0 GO:0071569 protein ufmylation(GO:0071569)
0.0 0.1 GO:0000050 urea cycle(GO:0000050)
0.0 0.6 GO:0006959 humoral immune response(GO:0006959)
0.0 0.1 GO:0043249 erythrocyte maturation(GO:0043249)
0.0 0.1 GO:0042987 amyloid precursor protein catabolic process(GO:0042987)
0.0 0.1 GO:0046504 ether lipid biosynthetic process(GO:0008611) glycerol ether biosynthetic process(GO:0046504) ether biosynthetic process(GO:1901503)
0.0 0.0 GO:0033131 regulation of glucokinase activity(GO:0033131) positive regulation of glucokinase activity(GO:0033133) regulation of hexokinase activity(GO:1903299) positive regulation of hexokinase activity(GO:1903301)
0.0 0.0 GO:0072162 mesenchymal cell differentiation involved in kidney development(GO:0072161) metanephric mesenchymal cell differentiation(GO:0072162) mesenchymal cell differentiation involved in renal system development(GO:2001012)
0.0 0.2 GO:2000117 negative regulation of cysteine-type endopeptidase activity involved in apoptotic process(GO:0043154) negative regulation of cysteine-type endopeptidase activity(GO:2000117)
0.0 0.1 GO:0042359 vitamin D metabolic process(GO:0042359)
0.0 0.0 GO:0033483 gas homeostasis(GO:0033483)
0.0 0.2 GO:0006783 heme biosynthetic process(GO:0006783)
0.0 0.3 GO:0071377 cellular response to glucagon stimulus(GO:0071377)
0.0 0.0 GO:0048147 negative regulation of fibroblast proliferation(GO:0048147)
0.0 0.0 GO:0009972 cytidine catabolic process(GO:0006216) cytidine deamination(GO:0009972) cytidine metabolic process(GO:0046087)
0.0 0.2 GO:0007190 activation of adenylate cyclase activity(GO:0007190)
0.0 0.0 GO:0007090 obsolete regulation of S phase of mitotic cell cycle(GO:0007090)
0.0 0.1 GO:0002209 behavioral defense response(GO:0002209)
0.0 0.5 GO:0008360 regulation of cell shape(GO:0008360)
0.0 0.0 GO:0046856 phosphatidylinositol dephosphorylation(GO:0046856)
0.0 0.1 GO:0033540 fatty acid beta-oxidation using acyl-CoA oxidase(GO:0033540)
0.0 0.0 GO:0000239 pachytene(GO:0000239)
0.0 0.0 GO:0048496 maintenance of organ identity(GO:0048496)
0.0 0.0 GO:0002282 microglial cell activation involved in immune response(GO:0002282)
0.0 0.4 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.0 0.0 GO:0031033 myosin filament organization(GO:0031033)
0.0 0.0 GO:0033522 histone H2A ubiquitination(GO:0033522)
0.0 0.1 GO:0045814 negative regulation of gene expression, epigenetic(GO:0045814)
0.0 0.0 GO:0050435 beta-amyloid metabolic process(GO:0050435)
0.0 0.0 GO:0001675 acrosome assembly(GO:0001675)
0.0 0.0 GO:0021798 forebrain dorsal/ventral pattern formation(GO:0021798)
0.0 0.0 GO:0070670 response to interleukin-4(GO:0070670)
0.0 0.0 GO:0070634 transepithelial ammonium transport(GO:0070634)
0.0 0.0 GO:0032042 mitochondrial DNA metabolic process(GO:0032042)
0.0 0.1 GO:0051918 negative regulation of fibrinolysis(GO:0051918)
0.0 0.0 GO:0045824 negative regulation of innate immune response(GO:0045824)
0.0 0.5 GO:0006986 response to unfolded protein(GO:0006986)
0.0 0.0 GO:0071285 cellular response to lithium ion(GO:0071285)
0.0 0.0 GO:0008653 lipopolysaccharide metabolic process(GO:0008653)
0.0 1.2 GO:0043087 regulation of GTPase activity(GO:0043087)
0.0 0.0 GO:0030851 granulocyte differentiation(GO:0030851)
0.0 0.0 GO:0000463 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000463) maturation of LSU-rRNA(GO:0000470)
0.0 0.1 GO:0009312 oligosaccharide biosynthetic process(GO:0009312)
0.0 0.0 GO:0033687 osteoblast proliferation(GO:0033687)
0.0 0.0 GO:0018206 peptidyl-methionine modification(GO:0018206)
0.0 0.1 GO:0051496 positive regulation of stress fiber assembly(GO:0051496)
0.0 0.0 GO:0042532 negative regulation of tyrosine phosphorylation of Stat3 protein(GO:0042518) negative regulation of tyrosine phosphorylation of STAT protein(GO:0042532)
0.0 0.1 GO:0032012 regulation of ARF protein signal transduction(GO:0032012)
0.0 0.1 GO:0007194 negative regulation of adenylate cyclase activity(GO:0007194) negative regulation of cyclase activity(GO:0031280) negative regulation of lyase activity(GO:0051350)
0.0 0.0 GO:1903963 arachidonic acid secretion(GO:0050482) arachidonate transport(GO:1903963)
0.0 0.2 GO:0006306 DNA alkylation(GO:0006305) DNA methylation(GO:0006306)
0.0 0.0 GO:0046337 phosphatidylethanolamine biosynthetic process(GO:0006646) phosphatidylethanolamine metabolic process(GO:0046337)
0.0 0.1 GO:0008299 isoprenoid biosynthetic process(GO:0008299)
0.0 0.0 GO:0072234 metanephric tubule development(GO:0072170) metanephric epithelium development(GO:0072207) metanephric nephron tubule development(GO:0072234) metanephric nephron epithelium development(GO:0072243)
0.0 0.0 GO:0043628 ncRNA 3'-end processing(GO:0043628)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.8 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)
0.1 0.4 GO:0034993 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.1 0.6 GO:0031264 death-inducing signaling complex(GO:0031264)
0.1 0.8 GO:0001891 phagocytic cup(GO:0001891)
0.1 0.2 GO:0070022 transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.1 0.2 GO:0000942 condensed nuclear chromosome outer kinetochore(GO:0000942)
0.1 0.2 GO:0071942 XPC complex(GO:0071942)
0.1 0.8 GO:0030877 beta-catenin destruction complex(GO:0030877)
0.1 0.2 GO:0005896 interleukin-6 receptor complex(GO:0005896)
0.1 0.2 GO:0030008 TRAPP complex(GO:0030008)
0.1 0.2 GO:0031205 endoplasmic reticulum Sec complex(GO:0031205)
0.1 0.2 GO:0005827 polar microtubule(GO:0005827)
0.1 0.7 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.1 0.4 GO:0005885 Arp2/3 protein complex(GO:0005885)
0.1 0.2 GO:0005639 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229) nuclear membrane part(GO:0044453)
0.1 0.2 GO:0000138 Golgi trans cisterna(GO:0000138)
0.1 0.1 GO:0031465 Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
0.1 0.2 GO:0072487 MSL complex(GO:0072487)
0.1 0.2 GO:0032809 neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.1 0.3 GO:0031088 platelet dense granule membrane(GO:0031088)
0.1 0.5 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.0 0.7 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.0 0.1 GO:0032009 early phagosome(GO:0032009)
0.0 0.2 GO:0033553 rDNA heterochromatin(GO:0033553)
0.0 0.2 GO:0042405 nuclear inclusion body(GO:0042405)
0.0 0.5 GO:0001772 immunological synapse(GO:0001772)
0.0 0.5 GO:0035631 CD40 receptor complex(GO:0035631)
0.0 0.1 GO:1903561 extracellular exosome(GO:0070062) extracellular vesicle(GO:1903561)
0.0 0.1 GO:0070937 CRD-mediated mRNA stability complex(GO:0070937)
0.0 0.2 GO:0045240 dihydrolipoyl dehydrogenase complex(GO:0045240)
0.0 0.2 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
0.0 0.5 GO:0031519 PcG protein complex(GO:0031519)
0.0 0.3 GO:0048786 presynaptic active zone(GO:0048786)
0.0 0.1 GO:0032299 ribonuclease H2 complex(GO:0032299)
0.0 0.1 GO:0005850 eukaryotic translation initiation factor 2 complex(GO:0005850)
0.0 0.4 GO:0016471 vacuolar proton-transporting V-type ATPase complex(GO:0016471)
0.0 0.1 GO:0000137 Golgi cis cisterna(GO:0000137)
0.0 0.4 GO:0016585 obsolete chromatin remodeling complex(GO:0016585)
0.0 0.5 GO:0043209 myelin sheath(GO:0043209)
0.0 0.1 GO:0005797 Golgi medial cisterna(GO:0005797)
0.0 0.1 GO:0035189 Rb-E2F complex(GO:0035189)
0.0 0.1 GO:0031371 ubiquitin conjugating enzyme complex(GO:0031371)
0.0 0.3 GO:0042598 obsolete vesicular fraction(GO:0042598)
0.0 0.5 GO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
0.0 0.8 GO:0030131 clathrin adaptor complex(GO:0030131)
0.0 0.2 GO:0005577 fibrinogen complex(GO:0005577)
0.0 0.1 GO:0001931 uropod(GO:0001931) cell trailing edge(GO:0031254)
0.0 0.3 GO:0034518 mRNA cap binding complex(GO:0005845) RNA cap binding complex(GO:0034518)
0.0 0.1 GO:0005594 collagen type IX trimer(GO:0005594)
0.0 0.2 GO:0031464 Cul4A-RING E3 ubiquitin ligase complex(GO:0031464)
0.0 0.1 GO:0070695 FHF complex(GO:0070695)
0.0 0.1 GO:0045334 clathrin-coated endocytic vesicle(GO:0045334)
0.0 0.1 GO:0017071 intracellular cyclic nucleotide activated cation channel complex(GO:0017071)
0.0 0.1 GO:1990316 ATG1/ULK1 kinase complex(GO:1990316)
0.0 0.0 GO:0000800 lateral element(GO:0000800)
0.0 0.5 GO:0005637 nuclear inner membrane(GO:0005637)
0.0 0.0 GO:0060200 clathrin-sculpted acetylcholine transport vesicle(GO:0060200) clathrin-sculpted acetylcholine transport vesicle membrane(GO:0060201)
0.0 0.4 GO:0030530 obsolete heterogeneous nuclear ribonucleoprotein complex(GO:0030530)
0.0 0.3 GO:0042588 zymogen granule(GO:0042588)
0.0 0.1 GO:0070188 obsolete Stn1-Ten1 complex(GO:0070188)
0.0 0.1 GO:0001740 Barr body(GO:0001740)
0.0 0.1 GO:0000407 pre-autophagosomal structure(GO:0000407)
0.0 0.1 GO:0010369 chromocenter(GO:0010369)
0.0 0.2 GO:0005662 DNA replication factor A complex(GO:0005662)
0.0 0.1 GO:0016939 kinesin II complex(GO:0016939)
0.0 0.2 GO:0031080 nuclear pore outer ring(GO:0031080)
0.0 0.2 GO:0034464 BBSome(GO:0034464)
0.0 0.1 GO:0000153 cytoplasmic ubiquitin ligase complex(GO:0000153)
0.0 0.1 GO:0008540 proteasome regulatory particle, base subcomplex(GO:0008540)
0.0 0.0 GO:0000306 extrinsic component of vacuolar membrane(GO:0000306) extrinsic component of endosome membrane(GO:0031313)
0.0 0.0 GO:0044462 external encapsulating structure part(GO:0044462)
0.0 0.1 GO:0001940 male pronucleus(GO:0001940)
0.0 0.1 GO:0030673 axolemma(GO:0030673)
0.0 0.1 GO:0072669 tRNA-splicing ligase complex(GO:0072669)
0.0 0.7 GO:0030175 filopodium(GO:0030175)
0.0 0.1 GO:0070761 pre-snoRNP complex(GO:0070761)
0.0 0.1 GO:0071438 invadopodium membrane(GO:0071438)
0.0 0.1 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.0 0.1 GO:0071986 Ragulator complex(GO:0071986)
0.0 0.1 GO:0030897 HOPS complex(GO:0030897)
0.0 0.1 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.0 0.1 GO:0042788 polysomal ribosome(GO:0042788)
0.0 0.1 GO:0000444 MIS12/MIND type complex(GO:0000444)
0.0 0.1 GO:0005719 nuclear euchromatin(GO:0005719)
0.0 0.1 GO:0042825 TAP complex(GO:0042825)
0.0 0.1 GO:0044224 juxtaparanode region of axon(GO:0044224)
0.0 0.1 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.0 0.3 GO:0005852 eukaryotic translation initiation factor 3 complex(GO:0005852)
0.0 0.1 GO:0048188 Set1C/COMPASS complex(GO:0048188)
0.0 0.1 GO:0008290 F-actin capping protein complex(GO:0008290)
0.0 0.1 GO:0005658 alpha DNA polymerase:primase complex(GO:0005658)
0.0 0.1 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.0 0.2 GO:0008180 COP9 signalosome(GO:0008180)
0.0 0.1 GO:0033276 transcription factor TFTC complex(GO:0033276)
0.0 0.0 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.0 0.1 GO:0005641 nuclear envelope lumen(GO:0005641)
0.0 0.0 GO:0030119 AP-type membrane coat adaptor complex(GO:0030119)
0.0 0.1 GO:0002080 acrosomal membrane(GO:0002080)
0.0 0.4 GO:0044665 MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339)
0.0 0.2 GO:0032039 integrator complex(GO:0032039)
0.0 0.1 GO:0043601 replisome(GO:0030894) nuclear replisome(GO:0043601)
0.0 0.1 GO:0005958 DNA-dependent protein kinase-DNA ligase 4 complex(GO:0005958)
0.0 0.6 GO:0030964 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0 0.0 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
0.0 0.2 GO:0005849 mRNA cleavage factor complex(GO:0005849)
0.0 0.1 GO:0005828 kinetochore microtubule(GO:0005828)
0.0 0.1 GO:0031095 platelet dense tubular network membrane(GO:0031095)
0.0 0.2 GO:0005669 transcription factor TFIID complex(GO:0005669)
0.0 0.1 GO:0030670 phagocytic vesicle membrane(GO:0030670)
0.0 0.0 GO:0001652 granular component(GO:0001652)
0.0 0.8 GO:0016605 PML body(GO:0016605)
0.0 1.0 GO:0000790 nuclear chromatin(GO:0000790)
0.0 0.1 GO:0061202 clathrin-sculpted gamma-aminobutyric acid transport vesicle(GO:0061200) clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane(GO:0061202)
0.0 0.1 GO:0043596 nuclear replication fork(GO:0043596)
0.0 0.1 GO:0008278 cohesin complex(GO:0008278)
0.0 0.1 GO:0042575 DNA polymerase complex(GO:0042575)
0.0 0.1 GO:0033011 perinuclear theca(GO:0033011)
0.0 0.1 GO:0005838 proteasome regulatory particle(GO:0005838)
0.0 0.9 GO:0098562 cytoplasmic side of membrane(GO:0098562)
0.0 0.0 GO:0033185 mannosyltransferase complex(GO:0031501) dolichol-phosphate-mannose synthase complex(GO:0033185)
0.0 0.1 GO:0008274 gamma-tubulin large complex(GO:0000931) gamma-tubulin ring complex(GO:0008274)
0.0 0.1 GO:0005732 small nucleolar ribonucleoprotein complex(GO:0005732)
0.0 0.0 GO:0042584 chromaffin granule(GO:0042583) chromaffin granule membrane(GO:0042584)
0.0 0.1 GO:0032590 dendrite membrane(GO:0032590)
0.0 0.6 GO:0031902 late endosome membrane(GO:0031902)
0.0 0.2 GO:0005763 organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.0 0.0 GO:0045323 interleukin-1 receptor complex(GO:0045323)
0.0 0.1 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.0 0.1 GO:0000801 central element(GO:0000801)
0.0 0.4 GO:0017053 transcriptional repressor complex(GO:0017053)
0.0 0.2 GO:0031201 SNARE complex(GO:0031201)
0.0 0.5 GO:0055037 recycling endosome(GO:0055037)
0.0 0.2 GO:0005801 cis-Golgi network(GO:0005801)
0.0 0.3 GO:0005680 anaphase-promoting complex(GO:0005680)
0.0 0.1 GO:0060293 P granule(GO:0043186) pole plasm(GO:0045495) germ plasm(GO:0060293)
0.0 0.1 GO:0005844 polysome(GO:0005844)
0.0 0.1 GO:0005682 U5 snRNP(GO:0005682)
0.0 0.3 GO:0030863 cortical cytoskeleton(GO:0030863)
0.0 0.0 GO:0000778 condensed nuclear chromosome kinetochore(GO:0000778)
0.0 0.1 GO:0001917 photoreceptor inner segment(GO:0001917)
0.0 0.0 GO:0042599 lamellar body(GO:0042599)
0.0 0.3 GO:0032587 ruffle membrane(GO:0032587)
0.0 0.5 GO:0005770 late endosome(GO:0005770)
0.0 0.1 GO:0034362 low-density lipoprotein particle(GO:0034362)
0.0 0.0 GO:0070545 PeBoW complex(GO:0070545)
0.0 0.0 GO:0000214 tRNA-intron endonuclease complex(GO:0000214)
0.0 0.1 GO:0030137 COPI-coated vesicle(GO:0030137)
0.0 0.0 GO:0016589 NURF complex(GO:0016589)
0.0 0.1 GO:0043190 ATP-binding cassette (ABC) transporter complex(GO:0043190)
0.0 0.3 GO:0005921 gap junction(GO:0005921)
0.0 0.1 GO:0016011 dystroglycan complex(GO:0016011)
0.0 0.2 GO:0032982 myosin filament(GO:0032982)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.6 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.2 0.5 GO:0031628 opioid receptor binding(GO:0031628)
0.1 0.4 GO:0033691 sialic acid binding(GO:0033691)
0.1 0.8 GO:0016494 C-X-C chemokine receptor activity(GO:0016494)
0.1 0.4 GO:0016309 1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
0.1 0.4 GO:0030375 thyroid hormone receptor coactivator activity(GO:0030375)
0.1 0.3 GO:0042608 T cell receptor binding(GO:0042608)
0.1 0.3 GO:0016941 natriuretic peptide receptor activity(GO:0016941)
0.1 0.3 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.1 0.4 GO:0030284 estrogen receptor activity(GO:0030284)
0.1 0.9 GO:0046625 sphingolipid binding(GO:0046625)
0.1 0.2 GO:0032296 ribonuclease III activity(GO:0004525) double-stranded RNA-specific ribonuclease activity(GO:0032296)
0.1 0.2 GO:0003953 NAD+ nucleosidase activity(GO:0003953)
0.1 0.2 GO:0017162 aryl hydrocarbon receptor binding(GO:0017162)
0.1 1.1 GO:0004697 protein kinase C activity(GO:0004697)
0.1 0.3 GO:0047238 glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity(GO:0047238)
0.1 0.6 GO:0034593 phosphatidylinositol bisphosphate phosphatase activity(GO:0034593)
0.1 0.3 GO:0004046 aminoacylase activity(GO:0004046)
0.1 0.1 GO:0015185 gamma-aminobutyric acid transmembrane transporter activity(GO:0015185)
0.1 0.2 GO:0016842 amidine-lyase activity(GO:0016842)
0.1 1.5 GO:0001608 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.1 0.1 GO:0035014 phosphatidylinositol 3-kinase regulator activity(GO:0035014)
0.1 0.2 GO:0005131 growth hormone receptor binding(GO:0005131)
0.1 0.8 GO:0030159 receptor signaling complex scaffold activity(GO:0030159)
0.1 0.2 GO:0008474 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.1 0.4 GO:0070087 chromo shadow domain binding(GO:0070087)
0.1 0.2 GO:0002060 purine nucleobase binding(GO:0002060)
0.1 0.2 GO:0003726 double-stranded RNA adenosine deaminase activity(GO:0003726)
0.1 0.6 GO:0016493 C-C chemokine receptor activity(GO:0016493)
0.1 0.3 GO:0005521 lamin binding(GO:0005521)
0.1 0.2 GO:0070053 thrombospondin receptor activity(GO:0070053)
0.1 0.1 GO:0050253 retinyl-palmitate esterase activity(GO:0050253)
0.1 0.2 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454)
0.1 0.5 GO:0004579 dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.1 0.2 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.1 0.8 GO:0031593 polyubiquitin binding(GO:0031593)
0.1 0.3 GO:0005143 interleukin-12 receptor binding(GO:0005143)
0.1 0.2 GO:0004939 beta-adrenergic receptor activity(GO:0004939)
0.1 0.4 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.1 0.1 GO:0019870 potassium channel inhibitor activity(GO:0019870)
0.1 0.2 GO:0000405 bubble DNA binding(GO:0000405)
0.0 0.3 GO:0001784 phosphotyrosine binding(GO:0001784)
0.0 0.4 GO:0030276 clathrin binding(GO:0030276)
0.0 0.3 GO:0050733 RS domain binding(GO:0050733)
0.0 0.3 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.0 0.2 GO:0004957 prostaglandin E receptor activity(GO:0004957)
0.0 0.1 GO:0070548 L-glutamine aminotransferase activity(GO:0070548)
0.0 0.1 GO:0016748 succinyltransferase activity(GO:0016748)
0.0 1.8 GO:0101005 thiol-dependent ubiquitin-specific protease activity(GO:0004843) thiol-dependent ubiquitinyl hydrolase activity(GO:0036459) ubiquitinyl hydrolase activity(GO:0101005)
0.0 0.2 GO:0004897 ciliary neurotrophic factor receptor activity(GO:0004897)
0.0 0.4 GO:0003785 actin monomer binding(GO:0003785)
0.0 0.3 GO:0070410 co-SMAD binding(GO:0070410)
0.0 0.7 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.0 0.1 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
0.0 0.2 GO:0046934 phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) phosphatidylinositol bisphosphate kinase activity(GO:0052813)
0.0 0.1 GO:0046975 histone methyltransferase activity (H3-K36 specific)(GO:0046975)
0.0 0.4 GO:0005283 sodium:amino acid symporter activity(GO:0005283)
0.0 0.1 GO:0004677 DNA-dependent protein kinase activity(GO:0004677)
0.0 0.1 GO:0004311 farnesyltranstransferase activity(GO:0004311)
0.0 1.1 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.0 0.1 GO:0004911 interleukin-2 receptor activity(GO:0004911)
0.0 0.1 GO:0070643 vitamin D3 25-hydroxylase activity(GO:0030343) vitamin D 25-hydroxylase activity(GO:0070643)
0.0 0.2 GO:0016423 tRNA (guanine) methyltransferase activity(GO:0016423)
0.0 0.5 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.0 0.2 GO:0070403 NAD+ binding(GO:0070403)
0.0 0.2 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.0 0.2 GO:0031996 thioesterase binding(GO:0031996)
0.0 0.1 GO:0000064 L-ornithine transmembrane transporter activity(GO:0000064)
0.0 0.2 GO:0016308 1-phosphatidylinositol-4-phosphate 5-kinase activity(GO:0016308)
0.0 0.2 GO:0046974 histone methyltransferase activity (H3-K9 specific)(GO:0046974)
0.0 1.9 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.0 0.1 GO:0004013 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.0 0.3 GO:0004176 ATP-dependent peptidase activity(GO:0004176)
0.0 0.4 GO:0030742 GTP-dependent protein binding(GO:0030742)
0.0 0.1 GO:0043140 ATP-dependent 3'-5' DNA helicase activity(GO:0043140)
0.0 0.3 GO:0004568 chitinase activity(GO:0004568)
0.0 0.2 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.0 0.2 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0 0.3 GO:0042834 peptidoglycan binding(GO:0042834)
0.0 0.8 GO:0003725 double-stranded RNA binding(GO:0003725)
0.0 0.1 GO:0004784 superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
0.0 0.1 GO:0035197 siRNA binding(GO:0035197)
0.0 0.2 GO:0070567 cytidylyltransferase activity(GO:0070567)
0.0 0.2 GO:0003711 obsolete transcription elongation regulator activity(GO:0003711)
0.0 0.1 GO:0015379 potassium:chloride symporter activity(GO:0015379)
0.0 0.7 GO:0004003 ATP-dependent DNA helicase activity(GO:0004003)
0.0 0.2 GO:0051400 BH domain binding(GO:0051400)
0.0 0.1 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.0 0.7 GO:0003746 translation elongation factor activity(GO:0003746)
0.0 0.1 GO:0005114 type II transforming growth factor beta receptor binding(GO:0005114)
0.0 0.1 GO:0004127 cytidylate kinase activity(GO:0004127)
0.0 0.1 GO:0015333 peptide:proton symporter activity(GO:0015333) proton-dependent peptide secondary active transmembrane transporter activity(GO:0022897)
0.0 0.1 GO:0030881 beta-2-microglobulin binding(GO:0030881)
0.0 0.1 GO:0070735 protein-glycine ligase activity(GO:0070735)
0.0 0.1 GO:0047756 chondroitin 4-sulfotransferase activity(GO:0047756)
0.0 0.3 GO:0035251 UDP-glucosyltransferase activity(GO:0035251)
0.0 0.1 GO:0043141 ATP-dependent 5'-3' DNA helicase activity(GO:0043141)
0.0 0.1 GO:0008420 CTD phosphatase activity(GO:0008420)
0.0 0.2 GO:0016417 S-acyltransferase activity(GO:0016417)
0.0 0.0 GO:0017128 phospholipid scramblase activity(GO:0017128)
0.0 0.4 GO:0005344 oxygen transporter activity(GO:0005344)
0.0 0.1 GO:0003985 acetyl-CoA C-acetyltransferase activity(GO:0003985)
0.0 0.2 GO:0031419 cobalamin binding(GO:0031419)
0.0 0.3 GO:0005402 sugar:proton symporter activity(GO:0005351) cation:sugar symporter activity(GO:0005402)
0.0 0.2 GO:0031702 type 1 angiotensin receptor binding(GO:0031702)
0.0 0.5 GO:0016505 peptidase activator activity involved in apoptotic process(GO:0016505)
0.0 0.1 GO:0004875 complement receptor activity(GO:0004875)
0.0 0.4 GO:0042162 telomeric DNA binding(GO:0042162)
0.0 0.1 GO:0016531 copper chaperone activity(GO:0016531)
0.0 0.1 GO:0000268 peroxisome targeting sequence binding(GO:0000268)
0.0 0.1 GO:0004370 glycerol kinase activity(GO:0004370)
0.0 0.1 GO:0036002 pre-mRNA binding(GO:0036002)
0.0 0.2 GO:0016778 diphosphotransferase activity(GO:0016778)
0.0 0.2 GO:0008889 glycerophosphodiester phosphodiesterase activity(GO:0008889)
0.0 0.1 GO:0048156 tau protein binding(GO:0048156)
0.0 0.3 GO:0016884 carbon-nitrogen ligase activity, with glutamine as amido-N-donor(GO:0016884)
0.0 0.1 GO:0034713 type I transforming growth factor beta receptor binding(GO:0034713)
0.0 0.1 GO:0004886 9-cis retinoic acid receptor activity(GO:0004886)
0.0 0.1 GO:0016520 growth hormone-releasing hormone receptor activity(GO:0016520)
0.0 0.1 GO:0004591 oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591)
0.0 0.2 GO:0070411 I-SMAD binding(GO:0070411)
0.0 0.1 GO:0055103 ligase regulator activity(GO:0055103) ubiquitin-protein transferase regulator activity(GO:0055106)
0.0 0.1 GO:0004719 protein-L-isoaspartate (D-aspartate) O-methyltransferase activity(GO:0004719)
0.0 0.2 GO:0050786 RAGE receptor binding(GO:0050786)
0.0 0.3 GO:0004383 guanylate cyclase activity(GO:0004383)
0.0 0.4 GO:0043022 ribosome binding(GO:0043022)
0.0 0.1 GO:0004614 phosphoglucomutase activity(GO:0004614)
0.0 0.1 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574) ATP-dependent microtubule motor activity(GO:1990939)
0.0 0.1 GO:0015925 galactosidase activity(GO:0015925)
0.0 0.0 GO:0001591 dopamine neurotransmitter receptor activity, coupled via Gi/Go(GO:0001591)
0.0 0.9 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.0 0.1 GO:0016312 inositol bisphosphate phosphatase activity(GO:0016312)
0.0 0.2 GO:0015166 polyol transmembrane transporter activity(GO:0015166)
0.0 0.2 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.0 0.1 GO:0004062 aryl sulfotransferase activity(GO:0004062)
0.0 0.1 GO:0016635 oxidoreductase activity, acting on the CH-CH group of donors, quinone or related compound as acceptor(GO:0016635)
0.0 0.1 GO:0046980 tapasin binding(GO:0046980)
0.0 0.2 GO:0046970 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041) histone deacetylase activity (H4-K16 specific)(GO:0034739) NAD-dependent histone deacetylase activity (H4-K16 specific)(GO:0046970)
0.0 0.3 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.0 0.4 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.0 0.1 GO:0008109 N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109)
0.0 0.1 GO:0004607 phosphatidylcholine-sterol O-acyltransferase activity(GO:0004607)
0.0 0.1 GO:0030492 hemoglobin binding(GO:0030492)
0.0 0.3 GO:0004016 adenylate cyclase activity(GO:0004016)
0.0 0.1 GO:0005087 Ran guanyl-nucleotide exchange factor activity(GO:0005087)
0.0 0.2 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.0 0.0 GO:0019958 C-X-C chemokine binding(GO:0019958) interleukin-8 binding(GO:0019959)
0.0 0.4 GO:0051117 ATPase binding(GO:0051117)
0.0 0.1 GO:0005149 interleukin-1 receptor binding(GO:0005149)
0.0 2.0 GO:0017124 SH3 domain binding(GO:0017124)
0.0 0.1 GO:0004366 glycerol-3-phosphate O-acyltransferase activity(GO:0004366)
0.0 0.2 GO:0051787 misfolded protein binding(GO:0051787)
0.0 0.2 GO:0003906 DNA-(apurinic or apyrimidinic site) lyase activity(GO:0003906)
0.0 0.2 GO:0017025 TBP-class protein binding(GO:0017025)
0.0 0.1 GO:0015520 tetracycline:proton antiporter activity(GO:0015520)
0.0 0.1 GO:0003988 acetyl-CoA C-acyltransferase activity(GO:0003988)
0.0 0.2 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.0 0.2 GO:0015347 sodium-independent organic anion transmembrane transporter activity(GO:0015347)
0.0 0.1 GO:0003857 3-hydroxyacyl-CoA dehydrogenase activity(GO:0003857)
0.0 0.1 GO:0019783 ubiquitin-like protein-specific protease activity(GO:0019783)
0.0 0.1 GO:0016774 phosphotransferase activity, carboxyl group as acceptor(GO:0016774)
0.0 0.1 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.0 0.2 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.0 0.2 GO:0051010 microtubule plus-end binding(GO:0051010)
0.0 0.2 GO:0004022 alcohol dehydrogenase (NAD) activity(GO:0004022)
0.0 0.3 GO:0010181 FMN binding(GO:0010181)
0.0 0.1 GO:0008020 G-protein coupled photoreceptor activity(GO:0008020)
0.0 0.1 GO:0003987 acetate-CoA ligase activity(GO:0003987)
0.0 0.1 GO:0031821 G-protein coupled serotonin receptor binding(GO:0031821)
0.0 0.1 GO:0043855 intracellular cyclic nucleotide activated cation channel activity(GO:0005221) cyclic nucleotide-gated ion channel activity(GO:0043855)
0.0 0.1 GO:0004437 obsolete inositol or phosphatidylinositol phosphatase activity(GO:0004437)
0.0 0.1 GO:0016882 cyclo-ligase activity(GO:0016882)
0.0 0.1 GO:0001609 G-protein coupled adenosine receptor activity(GO:0001609)
0.0 0.1 GO:0032139 dinucleotide insertion or deletion binding(GO:0032139)
0.0 0.1 GO:0030507 spectrin binding(GO:0030507)
0.0 0.2 GO:0003678 DNA helicase activity(GO:0003678)
0.0 0.5 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435)
0.0 0.1 GO:0046912 transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
0.0 0.1 GO:0047623 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.0 0.1 GO:0008494 translation activator activity(GO:0008494)
0.0 0.5 GO:0019003 GDP binding(GO:0019003)
0.0 0.0 GO:0043008 ATP-dependent protein binding(GO:0043008)
0.0 0.1 GO:0008486 diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486)
0.0 0.4 GO:0002039 p53 binding(GO:0002039)
0.0 0.1 GO:0070008 serine-type exopeptidase activity(GO:0070008)
0.0 0.1 GO:0005381 iron ion transmembrane transporter activity(GO:0005381)
0.0 0.1 GO:0004300 enoyl-CoA hydratase activity(GO:0004300)
0.0 0.1 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.0 0.2 GO:0016846 carbon-sulfur lyase activity(GO:0016846)
0.0 0.1 GO:0004814 arginine-tRNA ligase activity(GO:0004814)
0.0 0.1 GO:0004652 polynucleotide adenylyltransferase activity(GO:0004652)
0.0 0.3 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.0 0.0 GO:0031685 adenosine receptor binding(GO:0031685)
0.0 0.0 GO:0015349 thyroid hormone transmembrane transporter activity(GO:0015349)
0.0 0.2 GO:0051721 protein phosphatase 2A binding(GO:0051721)
0.0 0.1 GO:0016362 activin receptor activity, type II(GO:0016362)
0.0 0.0 GO:0005350 pyrimidine nucleobase transmembrane transporter activity(GO:0005350)
0.0 0.2 GO:0005095 GTPase inhibitor activity(GO:0005095)
0.0 0.6 GO:0003755 peptidyl-prolyl cis-trans isomerase activity(GO:0003755)
0.0 0.1 GO:0003997 acyl-CoA oxidase activity(GO:0003997)
0.0 0.1 GO:0016833 oxo-acid-lyase activity(GO:0016833)
0.0 0.2 GO:0015923 mannosidase activity(GO:0015923)
0.0 0.3 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0 0.4 GO:0004177 aminopeptidase activity(GO:0004177)
0.0 0.1 GO:0017049 GTP-Rho binding(GO:0017049)
0.0 0.1 GO:0016857 racemase and epimerase activity, acting on carbohydrates and derivatives(GO:0016857)
0.0 0.0 GO:0070579 methylcytosine dioxygenase activity(GO:0070579)
0.0 0.1 GO:0050811 GABA receptor binding(GO:0050811)
0.0 0.1 GO:0090482 vitamin transmembrane transporter activity(GO:0090482)
0.0 0.0 GO:0042910 xenobiotic-transporting ATPase activity(GO:0008559) xenobiotic transporter activity(GO:0042910)
0.0 0.0 GO:0070492 oligosaccharide binding(GO:0070492)
0.0 0.1 GO:0008526 phosphatidylinositol transporter activity(GO:0008526)
0.0 0.0 GO:0004706 JUN kinase kinase kinase activity(GO:0004706)
0.0 0.1 GO:0001640 adenylate cyclase inhibiting G-protein coupled glutamate receptor activity(GO:0001640) G-protein coupled glutamate receptor activity(GO:0098988)
0.0 0.1 GO:0019788 NEDD8 transferase activity(GO:0019788)
0.0 0.0 GO:0004045 aminoacyl-tRNA hydrolase activity(GO:0004045)
0.0 0.1 GO:0043422 protein kinase B binding(GO:0043422)
0.0 0.2 GO:0046875 ephrin receptor binding(GO:0046875)
0.0 0.2 GO:0016864 protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864)
0.0 0.1 GO:0019206 nucleoside kinase activity(GO:0019206)
0.0 0.0 GO:0031434 mitogen-activated protein kinase kinase binding(GO:0031434)
0.0 0.0 GO:0043175 RNA polymerase core enzyme binding(GO:0043175)
0.0 0.5 GO:0008137 NADH dehydrogenase activity(GO:0003954) NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0 0.1 GO:0034452 dynactin binding(GO:0034452)
0.0 0.0 GO:0030368 interleukin-17 receptor activity(GO:0030368)
0.0 0.0 GO:0000104 succinate dehydrogenase activity(GO:0000104)
0.0 0.1 GO:0019104 DNA N-glycosylase activity(GO:0019104)
0.0 0.0 GO:0004774 succinate-CoA ligase activity(GO:0004774)
0.0 0.3 GO:0030145 manganese ion binding(GO:0030145)
0.0 0.2 GO:0015125 bile acid transmembrane transporter activity(GO:0015125)
0.0 0.1 GO:0008440 inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440) inositol trisphosphate kinase activity(GO:0051766)
0.0 0.0 GO:0008242 omega peptidase activity(GO:0008242)
0.0 1.2 GO:0008234 cysteine-type peptidase activity(GO:0008234)
0.0 0.1 GO:0035255 ionotropic glutamate receptor binding(GO:0035255)
0.0 0.1 GO:0008079 translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079)
0.0 0.2 GO:0005246 calcium channel regulator activity(GO:0005246)
0.0 0.1 GO:0004950 G-protein coupled chemoattractant receptor activity(GO:0001637) chemokine receptor activity(GO:0004950)
0.0 0.1 GO:0015250 water channel activity(GO:0015250)
0.0 0.0 GO:0005176 ErbB-2 class receptor binding(GO:0005176)
0.0 0.1 GO:0034190 apolipoprotein receptor binding(GO:0034190)
0.0 0.2 GO:0001540 beta-amyloid binding(GO:0001540)
0.0 0.7 GO:0008301 DNA binding, bending(GO:0008301)
0.0 0.1 GO:0035252 UDP-xylosyltransferase activity(GO:0035252) xylosyltransferase activity(GO:0042285)
0.0 0.1 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.0 0.0 GO:0000247 C-8 sterol isomerase activity(GO:0000247)
0.0 0.3 GO:0004869 cysteine-type endopeptidase inhibitor activity(GO:0004869)
0.0 0.0 GO:0030292 protein tyrosine kinase inhibitor activity(GO:0030292)
0.0 0.4 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.0 0.0 GO:0004999 vasoactive intestinal polypeptide receptor activity(GO:0004999)
0.0 0.0 GO:0042799 histone methyltransferase activity (H4-K20 specific)(GO:0042799)
0.0 0.0 GO:0004582 dolichyl-phosphate beta-D-mannosyltransferase activity(GO:0004582)
0.0 0.1 GO:0003945 N-acetyllactosamine synthase activity(GO:0003945)
0.0 0.1 GO:0015385 sodium:proton antiporter activity(GO:0015385)
0.0 0.0 GO:0004966 galanin receptor activity(GO:0004966)
0.0 0.1 GO:0015450 P-P-bond-hydrolysis-driven protein transmembrane transporter activity(GO:0015450)
0.0 0.2 GO:0005484 SNAP receptor activity(GO:0005484)
0.0 0.0 GO:0008384 IkappaB kinase activity(GO:0008384)
0.0 0.1 GO:0048531 beta-1,3-galactosyltransferase activity(GO:0048531)
0.0 0.1 GO:0019864 IgG binding(GO:0019864)
0.0 0.1 GO:0008131 primary amine oxidase activity(GO:0008131)
0.0 0.1 GO:0016805 dipeptidase activity(GO:0016805)
0.0 0.0 GO:0004142 diacylglycerol cholinephosphotransferase activity(GO:0004142)
0.0 0.1 GO:0003993 acid phosphatase activity(GO:0003993)
0.0 0.1 GO:0005487 nucleocytoplasmic transporter activity(GO:0005487)
0.0 0.1 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.0 0.0 GO:0008493 tetracycline transporter activity(GO:0008493)
0.0 0.0 GO:0008241 peptidyl-dipeptidase activity(GO:0008241)
0.0 0.0 GO:0031705 bombesin receptor binding(GO:0031705) endothelin B receptor binding(GO:0031708)
0.0 0.2 GO:0050699 WW domain binding(GO:0050699)
0.0 0.1 GO:0001786 phosphatidylserine binding(GO:0001786)
0.0 0.0 GO:0004974 leukotriene receptor activity(GO:0004974)
0.0 0.2 GO:0019212 phosphatase inhibitor activity(GO:0019212)
0.0 0.1 GO:0015355 secondary active monocarboxylate transmembrane transporter activity(GO:0015355)
0.0 0.1 GO:0016861 intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861)
0.0 0.0 GO:0047499 calcium-independent phospholipase A2 activity(GO:0047499)
0.0 0.0 GO:0016634 oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor(GO:0016634)
0.0 0.3 GO:0003724 RNA helicase activity(GO:0003724)
0.0 0.0 GO:0017159 pantetheine hydrolase activity(GO:0017159)
0.0 0.0 GO:0004629 phospholipase C activity(GO:0004629)
0.0 0.0 GO:0017070 U6 snRNA binding(GO:0017070)
0.0 0.1 GO:0016922 ligand-dependent nuclear receptor binding(GO:0016922)
0.0 0.0 GO:0071723 lipopeptide binding(GO:0071723)
0.0 0.0 GO:0003910 DNA ligase activity(GO:0003909) DNA ligase (ATP) activity(GO:0003910)
0.0 0.1 GO:0043130 ubiquitin binding(GO:0043130)
0.0 0.1 GO:0004550 nucleoside diphosphate kinase activity(GO:0004550)
0.0 0.2 GO:0016892 endoribonuclease activity, producing 3'-phosphomonoesters(GO:0016892)
0.0 0.3 GO:0004402 histone acetyltransferase activity(GO:0004402)
0.0 0.1 GO:0043014 alpha-tubulin binding(GO:0043014)
0.0 0.0 GO:0052834 inositol monophosphate 1-phosphatase activity(GO:0008934) inositol monophosphate phosphatase activity(GO:0052834)
0.0 0.2 GO:0016251 obsolete general RNA polymerase II transcription factor activity(GO:0016251)
0.0 0.1 GO:0005537 mannose binding(GO:0005537)
0.0 0.1 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.0 0.0 GO:0032558 purine deoxyribonucleotide binding(GO:0032554) adenyl deoxyribonucleotide binding(GO:0032558)
0.0 0.1 GO:0008536 Ran GTPase binding(GO:0008536)
0.0 0.0 GO:0003701 obsolete RNA polymerase I transcription factor activity(GO:0003701)
0.0 0.0 GO:0022889 L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.0 0.1 GO:0009922 fatty acid elongase activity(GO:0009922)
0.0 0.0 GO:0004305 ethanolamine kinase activity(GO:0004305)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 5.4 PID CD8 TCR PATHWAY TCR signaling in naïve CD8+ T cells
0.1 3.1 PID ERBB1 INTERNALIZATION PATHWAY Internalization of ErbB1
0.1 0.8 SA FAS SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.1 0.8 SA PTEN PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.1 0.1 PID IL5 PATHWAY IL5-mediated signaling events
0.1 1.0 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.1 1.0 PID TCR PATHWAY TCR signaling in naïve CD4+ T cells
0.1 0.1 SIG PIP3 SIGNALING IN B LYMPHOCYTES Genes related to PIP3 signaling in B lymphocytes
0.1 1.4 PID EPHRINB REV PATHWAY Ephrin B reverse signaling
0.1 0.2 PID TCR JNK PATHWAY JNK signaling in the CD4+ TCR pathway
0.1 2.6 PID AR TF PATHWAY Regulation of Androgen receptor activity
0.1 1.2 PID IL27 PATHWAY IL27-mediated signaling events
0.1 0.8 PID THROMBIN PAR4 PATHWAY PAR4-mediated thrombin signaling events
0.0 0.4 PID INTEGRIN3 PATHWAY Beta3 integrin cell surface interactions
0.0 0.3 SA B CELL RECEPTOR COMPLEXES Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.0 0.6 PID NFKAPPAB CANONICAL PATHWAY Canonical NF-kappaB pathway
0.0 0.1 PID HDAC CLASSII PATHWAY Signaling events mediated by HDAC Class II
0.0 0.4 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
0.0 0.8 PID WNT CANONICAL PATHWAY Canonical Wnt signaling pathway
0.0 0.0 ST TUMOR NECROSIS FACTOR PATHWAY Tumor Necrosis Factor Pathway.
0.0 0.1 PID SYNDECAN 1 PATHWAY Syndecan-1-mediated signaling events
0.0 1.1 PID TNF PATHWAY TNF receptor signaling pathway
0.0 0.1 PID BETA CATENIN DEG PATHWAY Degradation of beta catenin
0.0 0.5 PID LPA4 PATHWAY LPA4-mediated signaling events
0.0 0.3 PID ARF6 PATHWAY Arf6 signaling events
0.0 0.4 ST G ALPHA S PATHWAY G alpha s Pathway
0.0 1.2 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0 0.1 ST PAC1 RECEPTOR PATHWAY PAC1 Receptor Pathway
0.0 0.4 PID PI3KCI PATHWAY Class I PI3K signaling events
0.0 0.9 PID ECADHERIN NASCENT AJ PATHWAY E-cadherin signaling in the nascent adherens junction
0.0 0.6 PID IL8 CXCR2 PATHWAY IL8- and CXCR2-mediated signaling events
0.0 1.0 PID NFAT 3PATHWAY Role of Calcineurin-dependent NFAT signaling in lymphocytes
0.0 0.2 PID TRAIL PATHWAY TRAIL signaling pathway
0.0 0.7 PID BCR 5PATHWAY BCR signaling pathway
0.0 0.5 PID IL23 PATHWAY IL23-mediated signaling events
0.0 0.5 PID IL2 1PATHWAY IL2-mediated signaling events
0.0 0.2 PID IL2 PI3K PATHWAY IL2 signaling events mediated by PI3K
0.0 0.1 PID CD40 PATHWAY CD40/CD40L signaling
0.0 0.8 PID ILK PATHWAY Integrin-linked kinase signaling
0.0 0.0 PID LYMPH ANGIOGENESIS PATHWAY VEGFR3 signaling in lymphatic endothelium
0.0 0.2 PID IL2 STAT5 PATHWAY IL2 signaling events mediated by STAT5
0.0 0.3 PID ARF 3PATHWAY Arf1 pathway
0.0 0.3 PID P38 ALPHA BETA PATHWAY Regulation of p38-alpha and p38-beta
0.0 0.7 PID PLK1 PATHWAY PLK1 signaling events
0.0 0.0 ST INTERFERON GAMMA PATHWAY Interferon gamma pathway.
0.0 0.2 PID IL12 2PATHWAY IL12-mediated signaling events
0.0 0.1 SIG PIP3 SIGNALING IN CARDIAC MYOCTES Genes related to PIP3 signaling in cardiac myocytes
0.0 0.4 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.0 0.3 ST P38 MAPK PATHWAY p38 MAPK Pathway
0.0 0.5 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.0 0.4 PID RAC1 PATHWAY RAC1 signaling pathway
0.0 0.0 PID ER NONGENOMIC PATHWAY Plasma membrane estrogen receptor signaling
0.0 0.3 PID RAS PATHWAY Regulation of Ras family activation
0.0 0.2 PID MYC PATHWAY C-MYC pathway
0.0 0.1 PID AR NONGENOMIC PATHWAY Nongenotropic Androgen signaling
0.0 0.1 PID GMCSF PATHWAY GMCSF-mediated signaling events
0.0 0.0 PID ERBB4 PATHWAY ErbB4 signaling events
0.0 0.1 SIG CD40PATHWAYMAP Genes related to CD40 signaling
0.0 0.1 PID FOXO PATHWAY FoxO family signaling
0.0 0.5 PID P53 REGULATION PATHWAY p53 pathway
0.0 0.2 PID IL1 PATHWAY IL1-mediated signaling events
0.0 0.1 PID EPHA2 FWD PATHWAY EPHA2 forward signaling
0.0 0.1 PID SYNDECAN 2 PATHWAY Syndecan-2-mediated signaling events
0.0 0.1 PID FAK PATHWAY Signaling events mediated by focal adhesion kinase
0.0 0.3 PID ATR PATHWAY ATR signaling pathway
0.0 0.1 ST FAS SIGNALING PATHWAY Fas Signaling Pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.9 REACTOME BINDING AND ENTRY OF HIV VIRION Genes involved in Binding and entry of HIV virion
0.2 2.3 REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.1 1.9 REACTOME GENERATION OF SECOND MESSENGER MOLECULES Genes involved in Generation of second messenger molecules
0.1 0.9 REACTOME CD28 DEPENDENT VAV1 PATHWAY Genes involved in CD28 dependent Vav1 pathway
0.1 0.2 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.1 0.8 REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.1 1.8 REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.1 0.1 REACTOME THROMBOXANE SIGNALLING THROUGH TP RECEPTOR Genes involved in Thromboxane signalling through TP receptor
0.1 0.1 REACTOME ANTIGEN PROCESSING CROSS PRESENTATION Genes involved in Antigen processing-Cross presentation
0.1 0.6 REACTOME SPRY REGULATION OF FGF SIGNALING Genes involved in Spry regulation of FGF signaling
0.1 0.9 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.1 0.8 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.1 0.1 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.1 0.5 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
0.1 1.2 REACTOME IL RECEPTOR SHC SIGNALING Genes involved in Interleukin receptor SHC signaling
0.1 1.3 REACTOME RORA ACTIVATES CIRCADIAN EXPRESSION Genes involved in RORA Activates Circadian Expression
0.1 0.6 REACTOME GRB2 SOS PROVIDES LINKAGE TO MAPK SIGNALING FOR INTERGRINS Genes involved in GRB2:SOS provides linkage to MAPK signaling for Intergrins
0.1 1.0 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.1 0.1 REACTOME SCFSKP2 MEDIATED DEGRADATION OF P27 P21 Genes involved in SCF(Skp2)-mediated degradation of p27/p21
0.0 0.6 REACTOME CTNNB1 PHOSPHORYLATION CASCADE Genes involved in Beta-catenin phosphorylation cascade
0.0 1.0 REACTOME THE ROLE OF NEF IN HIV1 REPLICATION AND DISEASE PATHOGENESIS Genes involved in The role of Nef in HIV-1 replication and disease pathogenesis
0.0 1.3 REACTOME NOD1 2 SIGNALING PATHWAY Genes involved in NOD1/2 Signaling Pathway
0.0 0.3 REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY Genes involved in Adenylate cyclase activating pathway
0.0 0.1 REACTOME ENDOSOMAL VACUOLAR PATHWAY Genes involved in Endosomal/Vacuolar pathway
0.0 0.2 REACTOME REGULATION OF SIGNALING BY CBL Genes involved in Regulation of signaling by CBL
0.0 0.5 REACTOME P2Y RECEPTORS Genes involved in P2Y receptors
0.0 0.9 REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE Genes involved in Synthesis of PIPs at the plasma membrane
0.0 0.1 REACTOME CTLA4 INHIBITORY SIGNALING Genes involved in CTLA4 inhibitory signaling
0.0 0.8 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.0 0.0 REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION Genes involved in activated TAK1 mediates p38 MAPK activation
0.0 0.5 REACTOME INFLAMMASOMES Genes involved in Inflammasomes
0.0 0.1 REACTOME DOWNSTREAM TCR SIGNALING Genes involved in Downstream TCR signaling
0.0 0.8 REACTOME POST NMDA RECEPTOR ACTIVATION EVENTS Genes involved in Post NMDA receptor activation events
0.0 0.2 REACTOME ACTIVATION OF NF KAPPAB IN B CELLS Genes involved in Activation of NF-kappaB in B Cells
0.0 0.2 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
0.0 1.6 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0 0.1 REACTOME TRAF3 DEPENDENT IRF ACTIVATION PATHWAY Genes involved in TRAF3-dependent IRF activation pathway
0.0 0.4 REACTOME TRAF6 MEDIATED NFKB ACTIVATION Genes involved in TRAF6 mediated NF-kB activation
0.0 0.4 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.0 0.1 REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.0 0.4 REACTOME PROCESSING OF INTRONLESS PRE MRNAS Genes involved in Processing of Intronless Pre-mRNAs
0.0 0.4 REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.0 0.8 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 0.2 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.0 0.5 REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.0 0.1 REACTOME LYSOSOME VESICLE BIOGENESIS Genes involved in Lysosome Vesicle Biogenesis
0.0 0.3 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
0.0 0.1 REACTOME ADENYLATE CYCLASE INHIBITORY PATHWAY Genes involved in Adenylate cyclase inhibitory pathway
0.0 0.1 REACTOME ACYL CHAIN REMODELLING OF PI Genes involved in Acyl chain remodelling of PI
0.0 0.2 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.0 0.2 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.0 0.0 REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
0.0 0.0 REACTOME PHOSPHORYLATION OF THE APC C Genes involved in Phosphorylation of the APC/C
0.0 0.1 REACTOME NUCLEOTIDE LIKE PURINERGIC RECEPTORS Genes involved in Nucleotide-like (purinergic) receptors
0.0 0.1 REACTOME IRAK1 RECRUITS IKK COMPLEX Genes involved in IRAK1 recruits IKK complex
0.0 0.1 REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS Genes involved in Membrane binding and targetting of GAG proteins
0.0 0.1 REACTOME RAF MAP KINASE CASCADE Genes involved in RAF/MAP kinase cascade
0.0 0.4 REACTOME REGULATORY RNA PATHWAYS Genes involved in Regulatory RNA pathways
0.0 0.5 REACTOME TRANSFERRIN ENDOCYTOSIS AND RECYCLING Genes involved in Transferrin endocytosis and recycling
0.0 0.1 REACTOME INHIBITION OF REPLICATION INITIATION OF DAMAGED DNA BY RB1 E2F1 Genes involved in Inhibition of replication initiation of damaged DNA by RB1/E2F1
0.0 0.2 REACTOME CALNEXIN CALRETICULIN CYCLE Genes involved in Calnexin/calreticulin cycle
0.0 0.0 REACTOME AUTODEGRADATION OF THE E3 UBIQUITIN LIGASE COP1 Genes involved in Autodegradation of the E3 ubiquitin ligase COP1
0.0 0.1 REACTOME DCC MEDIATED ATTRACTIVE SIGNALING Genes involved in DCC mediated attractive signaling
0.0 0.5 REACTOME MEIOTIC SYNAPSIS Genes involved in Meiotic Synapsis
0.0 0.3 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.0 0.1 REACTOME N GLYCAN ANTENNAE ELONGATION IN THE MEDIAL TRANS GOLGI Genes involved in N-glycan antennae elongation in the medial/trans-Golgi
0.0 0.1 REACTOME COPI MEDIATED TRANSPORT Genes involved in COPI Mediated Transport
0.0 0.5 REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS Genes involved in Apoptotic cleavage of cellular proteins
0.0 0.0 REACTOME IL 3 5 AND GM CSF SIGNALING Genes involved in Interleukin-3, 5 and GM-CSF signaling
0.0 0.3 REACTOME BOTULINUM NEUROTOXICITY Genes involved in Botulinum neurotoxicity
0.0 0.2 REACTOME HORMONE LIGAND BINDING RECEPTORS Genes involved in Hormone ligand-binding receptors
0.0 0.2 REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.0 0.2 REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.0 0.4 REACTOME KINESINS Genes involved in Kinesins
0.0 0.2 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.0 0.8 REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES Genes involved in Antiviral mechanism by IFN-stimulated genes
0.0 0.0 REACTOME ACYL CHAIN REMODELLING OF PS Genes involved in Acyl chain remodelling of PS
0.0 0.4 REACTOME CYTOSOLIC TRNA AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation
0.0 0.3 REACTOME HS GAG DEGRADATION Genes involved in HS-GAG degradation
0.0 0.5 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.0 0.1 REACTOME PROSTANOID LIGAND RECEPTORS Genes involved in Prostanoid ligand receptors
0.0 0.3 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.0 0.0 REACTOME GPVI MEDIATED ACTIVATION CASCADE Genes involved in GPVI-mediated activation cascade
0.0 0.1 REACTOME P38MAPK EVENTS Genes involved in p38MAPK events
0.0 0.7 REACTOME DESTABILIZATION OF MRNA BY AUF1 HNRNP D0 Genes involved in Destabilization of mRNA by AUF1 (hnRNP D0)
0.0 0.1 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.0 0.2 REACTOME CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
0.0 0.2 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.0 0.3 REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.0 0.2 REACTOME TRANSPORT OF ORGANIC ANIONS Genes involved in Transport of organic anions
0.0 0.0 REACTOME P75NTR RECRUITS SIGNALLING COMPLEXES Genes involved in p75NTR recruits signalling complexes
0.0 0.2 REACTOME RESOLUTION OF AP SITES VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY Genes involved in Resolution of AP sites via the single-nucleotide replacement pathway
0.0 0.1 REACTOME REGULATION OF ORNITHINE DECARBOXYLASE ODC Genes involved in Regulation of ornithine decarboxylase (ODC)
0.0 0.0 REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR Genes involved in Trafficking and processing of endosomal TLR
0.0 0.2 REACTOME AQUAPORIN MEDIATED TRANSPORT Genes involved in Aquaporin-mediated transport
0.0 0.0 REACTOME RNA POL I PROMOTER OPENING Genes involved in RNA Polymerase I Promoter Opening
0.0 0.3 REACTOME EXTENSION OF TELOMERES Genes involved in Extension of Telomeres
0.0 0.2 REACTOME COSTIMULATION BY THE CD28 FAMILY Genes involved in Costimulation by the CD28 family
0.0 0.2 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION Genes involved in TRAF6 mediated IRF7 activation
0.0 0.0 REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.0 0.5 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.0 0.1 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor
0.0 0.1 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.0 0.2 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.0 0.4 REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
0.0 0.0 REACTOME S PHASE Genes involved in S Phase
0.0 0.0 REACTOME RIP MEDIATED NFKB ACTIVATION VIA DAI Genes involved in RIP-mediated NFkB activation via DAI
0.0 0.2 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.0 0.5 REACTOME DEFENSINS Genes involved in Defensins
0.0 0.8 REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.0 0.1 REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE Genes involved in Synthesis of PIPs at the Golgi membrane
0.0 0.1 REACTOME G1 S SPECIFIC TRANSCRIPTION Genes involved in G1/S-Specific Transcription
0.0 0.1 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts
0.0 0.3 REACTOME SYNTHESIS OF PA Genes involved in Synthesis of PA
0.0 0.9 REACTOME RESPIRATORY ELECTRON TRANSPORT ATP SYNTHESIS BY CHEMIOSMOTIC COUPLING AND HEAT PRODUCTION BY UNCOUPLING PROTEINS Genes involved in Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins.
0.0 0.1 REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.0 0.0 REACTOME NEP NS2 INTERACTS WITH THE CELLULAR EXPORT MACHINERY Genes involved in NEP/NS2 Interacts with the Cellular Export Machinery
0.0 0.2 REACTOME INHIBITION OF INSULIN SECRETION BY ADRENALINE NORADRENALINE Genes involved in Inhibition of Insulin Secretion by Adrenaline/Noradrenaline
0.0 0.4 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 0.2 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.0 0.0 REACTOME ACYL CHAIN REMODELLING OF PG Genes involved in Acyl chain remodelling of PG
0.0 0.3 REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.0 0.6 REACTOME AMYLOIDS Genes involved in Amyloids
0.0 0.2 REACTOME MITOCHONDRIAL TRNA AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation