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ENCODE: H3K4me1 ChIP-Seq of primary human cells

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Results for SMAD4

Z-value: 1.46

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Transcription factors associated with SMAD4

Gene Symbol	Gene ID	Gene Info
SMAD4 Ensembl NCBI GeneCards UniProt	ENSG00000141646.9	SMAD family member 4

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE	Gene	Distance	Association probability	Pearson corr. coef.	P-value	Plot
chr18_48571697_48571848	SMAD4	443	0.867605	0.79	1.1e-02	Click!
chr18_48555568_48555814	SMAD4	293	0.926297	0.65	5.8e-02	Click!
chr18_48567402_48567553	SMAD4	3852	0.282596	-0.62	7.8e-02	Click!
chr18_48594327_48594478	SMAD4	919	0.648332	0.61	8.2e-02	Click!
chr18_48596100_48596251	SMAD4	2692	0.324545	0.60	8.9e-02	Click!

Activity of the SMAD4 motif across conditions

Conditions sorted by the z-value of the SMAD4 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE)	Target Score	Top associated gene	Gene Info	Distance of CRE to TSS	CRE/Gene association probability
chr19_42440645_42440990	0.96	ARHGEF1	Rho guanine nucleotide exchange factor (GEF) 1	13571	0.12
chr6_43081976_43082127	0.54	PTK7	protein tyrosine kinase 7	16278	0.11
chr1_94130651_94130802	0.43	BCAR3	breast cancer anti-estrogen resistance 3	16200	0.23
chr2_9389279_9389534	0.42	ASAP2	ArfGAP with SH3 domain, ankyrin repeat and PH domain 2	42512	0.19
chr19_55998538_55999092	0.41	SSC5D	scavenger receptor cysteine rich domain containing (5 domains)	956	0.27
chr17_6135420_6135694	0.40	ENSG00000206618	.	25074	0.24
chr17_26832783_26832934	0.38	FOXN1	forkhead box N1	403	0.73
chr17_78623105_78623534	0.38	RPTOR	regulatory associated protein of MTOR, complex 1	104051	0.06
chr20_60931015_60931270	0.38	RP11-157P1.5		3073	0.16
chr17_16977412_16977763	0.38	MPRIP-AS1	MPRIP antisense RNA 1	3479	0.23
chr12_116702764_116703198	0.37	ENSG00000263768	.	9188	0.22
chr16_88831505_88831885	0.37	PIEZO1	piezo-type mechanosensitive ion channel component 1	19924	0.07
chr1_6419961_6420398	0.36	ACOT7	acyl-CoA thioesterase 7	587	0.69
chr5_151079092_151079243	0.36	ENSG00000222102	.	4972	0.16
chr12_53626909_53627429	0.36	RARG	retinoic acid receptor, gamma	405	0.74
chr8_36999886_37000356	0.36	KCNU1	potassium channel, subfamily U, member 1	213698	0.02
chr5_156944293_156944560	0.35	ADAM19	ADAM metallopeptidase domain 19	14596	0.16
chr19_41139021_41139172	0.34	LTBP4	latent transforming growth factor beta binding protein 4	19274	0.12
chr6_170501516_170501667	0.34	RP11-302L19.1		23850	0.21
chr6_117870942_117871751	0.34	GOPC	golgi-associated PDZ and coiled-coil motif containing	52181	0.12
chr3_25466068_25466219	0.33	RARB	retinoic acid receptor, beta	3611	0.33
chr2_241391226_241391617	0.33	GPC1	glypican 1	807	0.55
chr1_7028963_7029357	0.33	RP11-334N17.1		45179	0.18
chr22_46502377_46502538	0.32	ENSG00000198986	.	6172	0.1
chr1_162666512_162666663	0.32	DDR2	discoidin domain receptor tyrosine kinase 2	64327	0.1
chr1_32166125_32166752	0.30	COL16A1	collagen, type XVI, alpha 1	3330	0.19
chr17_26832603_26832754	0.30	FOXN1	forkhead box N1	583	0.59
chr1_109796466_109796994	0.30	CELSR2	cadherin, EGF LAG seven-pass G-type receptor 2	4089	0.18
chr22_45949176_45949470	0.30	FBLN1	fibulin 1	34660	0.15
chr17_64670159_64670310	0.30	AC006947.1		2256	0.32
chr10_25351272_25351577	0.30	ENSG00000266069	.	29059	0.17
chr19_10829760_10829951	0.30	DNM2	dynamin 2	618	0.44
chr3_52124926_52125077	0.30	LINC00696	long intergenic non-protein coding RNA 696	27434	0.11
chr18_12403385_12403680	0.29	ENSG00000251937	.	3121	0.2
chr5_133846467_133846815	0.29	ENSG00000240250	.	6860	0.16
chr6_159205058_159205209	0.29	ENSG00000265558	.	19348	0.17
chr1_223406753_223407058	0.29	TLR5	toll-like receptor 5	90281	0.09
chr12_49934137_49934288	0.29	KCNH3	potassium voltage-gated channel, subfamily H (eag-related), member 3	1272	0.37
chr4_7633059_7633347	0.29	SORCS2	sortilin-related VPS10 domain containing receptor 2	102804	0.07
chr12_54412477_54412628	0.29	HOXC4	homeobox C4	1837	0.13
chr3_184434209_184434429	0.29	MAGEF1	melanoma antigen family F, 1	4483	0.3
chr2_219758153_219758511	0.29	WNT10A	wingless-type MMTV integration site family, member 10A	11449	0.11
chr18_72895850_72896001	0.28	ZADH2	zinc binding alcohol dehydrogenase domain containing 2	21543	0.23
chr1_210484845_210485129	0.28	HHAT	hedgehog acyltransferase	16609	0.23
chr16_19019374_19019525	0.28	ENSG00000207167	.	4030	0.19
chr15_67419351_67419566	0.28	SMAD3	SMAD family member 3	983	0.62
chr16_30538935_30539644	0.28	ZNF768	zinc finger protein 768	1147	0.22
chr13_110972322_110972473	0.28	COL4A2	collagen, type IV, alpha 2	12783	0.21
chr21_46719955_46720106	0.28	ENSG00000215447	.	12063	0.18
chr3_99591199_99591697	0.28	FILIP1L	filamin A interacting protein 1-like	3500	0.32
chr12_53272359_53272510	0.28	KRT8	keratin 8	23297	0.11
chr11_61321904_61322055	0.27	SYT7	synaptotagmin VII	26313	0.13
chr22_31479008_31479415	0.27	RP3-412A9.16		340	0.68
chr15_74713092_74713309	0.27	SEMA7A	semaphorin 7A, GPI membrane anchor (John Milton Hagen blood group)	12801	0.14
chr4_10107887_10108195	0.27	ENSG00000223086	.	9467	0.16
chr3_42557311_42557462	0.27	VIPR1	vasoactive intestinal peptide receptor 1	13271	0.15
chr19_42391298_42391529	0.27	ARHGEF1	Rho guanine nucleotide exchange factor (GEF) 1	2898	0.16
chr6_18043310_18043548	0.27	KIF13A	kinesin family member 13A	55575	0.13
chr11_92029038_92029189	0.27	FAT3	FAT atypical cadherin 3	56149	0.17
chr11_64610007_64610178	0.27	CDC42BPG	CDC42 binding protein kinase gamma (DMPK-like)	1949	0.2
chr7_79775488_79775920	0.27	GNAI1	guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1	10633	0.29
chr19_46284301_46284684	0.26	DMPK	dystrophia myotonica-protein kinase	487	0.59
chr1_231524073_231524266	0.26	EGLN1	egl-9 family hypoxia-inducible factor 1	36621	0.14
chr3_97591409_97591725	0.26	CRYBG3	beta-gamma crystallin domain containing 3	4252	0.29
chr16_31482844_31483179	0.26	TGFB1I1	transforming growth factor beta 1 induced transcript 1	105	0.92
chr12_122519590_122520270	0.26	MLXIP	MLX interacting protein	3302	0.29
chr8_143761558_143761709	0.26	PSCA	prostate stem cell antigen	241	0.87
chr15_86329808_86330000	0.26	KLHL25	kelch-like family member 25	8196	0.12
chr8_23213962_23214375	0.26	LOXL2	lysyl oxidase-like 2	14471	0.16
chr9_33129582_33129938	0.26	B4GALT1	UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1	1563	0.35
chr9_131749866_131750128	0.26	NUP188	nucleoporin 188kDa	40019	0.08
chr6_42082028_42082179	0.25	C6orf132	chromosome 6 open reading frame 132	28079	0.13
chr1_48337904_48338055	0.25	FLJ00388		110689	0.07
chr14_76287931_76288578	0.25	RP11-270M14.4		15300	0.24
chr11_66185325_66185605	0.25	NPAS4	neuronal PAS domain protein 4	3010	0.11
chr2_119998129_119998280	0.25	STEAP3	STEAP family member 3, metalloreductase	3843	0.24
chr14_90387952_90388103	0.25	EFCAB11	EF-hand calcium binding domain 11	32840	0.18
chr3_71083022_71083173	0.25	FOXP1	forkhead box P1	30980	0.25
chr9_707516_707782	0.25	KANK1	KN motif and ankyrin repeat domains 1	760	0.71
chr18_55873061_55873212	0.25	RP11-718I15.1		10208	0.22
chr2_233898227_233898378	0.25	NEU2	sialidase 2 (cytosolic sialidase)	920	0.54
chr16_75283886_75284037	0.25	BCAR1	breast cancer anti-estrogen resistance 1	97	0.96
chr7_69205040_69205191	0.25	AUTS2	autism susceptibility candidate 2	140518	0.05
chr17_73869045_73869430	0.25	TRIM47	tripartite motif containing 47	1736	0.17
chr3_3842280_3842488	0.25	LRRN1	leucine rich repeat neuronal 1	1263	0.64
chr1_230220237_230220388	0.25	GALNT2	UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 2 (GalNAc-T2)	17294	0.23
chr8_103757441_103757701	0.24	ENSG00000266799	.	11624	0.23
chr14_23447277_23447428	0.24	AJUBA	ajuba LIM protein	406	0.65
chr14_65228820_65229007	0.24	SPTB	spectrin, beta, erythrocytic	20355	0.18
chr20_35102989_35103140	0.24	DLGAP4	discs, large (Drosophila) homolog-associated protein 4	12914	0.19
chr14_76842625_76842923	0.24	ENSG00000263880	.	21422	0.18
chr12_122519012_122519447	0.24	MLXIP	MLX interacting protein	2601	0.32
chr19_42754822_42754973	0.24	ERF	Ets2 repressor factor	304	0.77
chr17_74704931_74705082	0.24	MXRA7	matrix-remodelling associated 7	673	0.47
chr8_117241839_117241990	0.24	ENSG00000264815	.	57674	0.15
chr11_65257627_65258285	0.24	SCYL1	SCY1-like 1 (S. cerevisiae)	34592	0.08
chr10_105522680_105522891	0.24	SH3PXD2A	SH3 and PX domains 2A	38270	0.16
chr8_8469190_8469379	0.24	ENSG00000264445	.	21690	0.2
chr7_69064920_69065071	0.24	AUTS2	autism susceptibility candidate 2	398	0.91
chr10_71517793_71518044	0.24	COL13A1	collagen, type XIII, alpha 1	43726	0.14
chr12_26441077_26441474	0.24	RP11-283G6.5		16422	0.18
chr19_44007319_44007471	0.24	PHLDB3	pleckstrin homology-like domain, family B, member 3	1171	0.34
chr2_235933793_235934065	0.23	SH3BP4	SH3-domain binding protein 4	30445	0.26
chr3_10437627_10437788	0.23	ENSG00000216135	.	1461	0.37
chr7_47446099_47446250	0.23	TNS3	tensin 3	46655	0.2
chr17_48114457_48114748	0.23	ITGA3	integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)	18737	0.13
chr1_41966963_41967114	0.23	EDN2	endothelin 2	16696	0.19
chr2_109858863_109859207	0.23	ENSG00000265965	.	71046	0.12
chr7_137355177_137355328	0.23	DGKI	diacylglycerol kinase, iota	176030	0.03
chr21_44913772_44914270	0.23	SIK1	salt-inducible kinase 1	67013	0.12
chr17_55520242_55520671	0.23	ENSG00000263902	.	30894	0.2
chr19_1138609_1138760	0.23	SBNO2	strawberry notch homolog 2 (Drosophila)	6464	0.12
chr2_216896555_216896804	0.23	MREG	melanoregulin	1003	0.59
chr9_134544593_134545249	0.23	RAPGEF1	Rap guanine nucleotide exchange factor (GEF) 1	40308	0.16
chr22_30609123_30609664	0.23	RP3-438O4.4		6295	0.13
chr1_12538935_12539451	0.23	VPS13D	vacuolar protein sorting 13 homolog D (S. cerevisiae)	589	0.77
chr3_14198972_14199123	0.23	AC093495.4		12557	0.15
chr4_146655160_146655429	0.23	ZNF827	zinc finger protein 827	30913	0.18
chr11_61657707_61658044	0.23	FADS3	fatty acid desaturase 3	978	0.43
chr2_33441413_33441564	0.23	LTBP1	latent transforming growth factor beta binding protein 1	27241	0.22
chr1_156094375_156094823	0.23	LMNA	lamin A/C	1352	0.29
chr17_54831967_54832582	0.22	C17orf67	chromosome 17 open reading frame 67	60976	0.11
chr17_47527935_47528264	0.22	ENSG00000207127	.	33887	0.1
chr10_99599816_99599967	0.22	GOLGA7B	golgin A7 family, member B	10105	0.18
chr3_126721307_126721580	0.22	PLXNA1	plexin A1	14006	0.29
chr2_20406865_20407016	0.22	SDC1	syndecan 1	17101	0.16
chr7_116357238_116357389	0.22	MET	met proto-oncogene	18174	0.23
chr17_43449881_43450075	0.22	CTB-39G8.3		24320	0.11
chr18_77722000_77722505	0.22	HSBP1L1	heat shock factor binding protein 1-like 1	2309	0.28
chr19_39647379_39647605	0.22	PAK4	p21 protein (Cdc42/Rac)-activated kinase 4	150	0.93
chr9_133988197_133988348	0.22	AIF1L	allograft inflammatory factor 1-like	1483	0.33
chr10_104381326_104381568	0.22	TRIM8	tripartite motif containing 8	22806	0.14
chr13_114540098_114540530	0.22	GAS6	growth arrest-specific 6	1297	0.5
chr7_40337996_40338297	0.22	SUGCT	succinylCoA:glutarate-CoA transferase	163527	0.04
chr17_45787218_45787648	0.22	TBKBP1	TBK1 binding protein 1	14803	0.13
chr17_38677307_38677600	0.22	TNS4	tensin 4	19604	0.15
chr2_224663300_224663451	0.22	AP1S3	adaptor-related protein complex 1, sigma 3 subunit	38826	0.2
chr16_4513814_4513965	0.22	NMRAL1	NmrA-like family domain containing 1	2286	0.2
chr22_45900834_45901064	0.22	FBLN1	fibulin 1	2023	0.36
chr12_52550857_52551131	0.22	KRT80	keratin 80	34790	0.09
chr10_99330916_99331067	0.22	ANKRD2	ankyrin repeat domain 2 (stretch responsive muscle)	1207	0.35
chr19_18550018_18550170	0.22	ISYNA1	inositol-3-phosphate synthase 1	983	0.33
chr7_76237813_76237964	0.22	POMZP3	POM121 and ZP3 fusion	9729	0.21
chr1_26145213_26145423	0.22	MTFR1L	mitochondrial fission regulator 1-like	187	0.83
chr12_116918222_116918535	0.22	ENSG00000264037	.	52255	0.15
chr16_89161333_89161741	0.22	ACSF3	acyl-CoA synthetase family member 3	1225	0.43
chr19_11379736_11379971	0.22	DOCK6	dedicator of cytokinesis 6	6725	0.11
chr15_40377183_40377334	0.22	RP11-521C20.3		3775	0.19
chr14_59824919_59825322	0.22	ENSG00000252869	.	41621	0.17
chr6_15962038_15962189	0.22	MYLIP	myosin regulatory light chain interacting protein	167243	0.03
chr15_90756571_90757151	0.22	SEMA4B	sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B	8121	0.12
chr17_76703299_76703450	0.22	CYTH1	cytohesin 1	9733	0.19
chr19_16936028_16936179	0.22	SIN3B	SIN3 transcription regulator family member B	4108	0.16
chr11_20134359_20134761	0.22	NAV2-AS1	NAV2 antisense RNA 1	7618	0.23
chr17_3460791_3460942	0.21	TRPV3	transient receptor potential cation channel, subfamily V, member 3	233	0.89
chr21_46719645_46719796	0.21	ENSG00000215447	.	11753	0.18
chr19_941240_941652	0.21	ARID3A	AT rich interactive domain 3A (BRIGHT-like)	8937	0.08
chr2_235372256_235372494	0.21	ARL4C	ADP-ribosylation factor-like 4C	32869	0.25
chr17_7745682_7745903	0.21	KDM6B	lysine (K)-specific demethylase 6B	2441	0.15
chr19_41731212_41731363	0.21	AXL	AXL receptor tyrosine kinase	1373	0.29
chr9_117050436_117050587	0.21	ORM1	orosomucoid 1	34825	0.15
chr20_33892412_33892646	0.21	FAM83C	family with sequence similarity 83, member C	12325	0.1
chr1_241646818_241646969	0.21	FH	fumarate hydratase	36168	0.18
chr19_50140369_50140520	0.21	RRAS	related RAS viral (r-ras) oncogene homolog	3014	0.1
chr14_75112427_75112728	0.21	AREL1	apoptosis resistant E3 ubiquitin protein ligase 1	30341	0.13
chr9_137443475_137443828	0.21	COL5A1	collagen, type V, alpha 1	89969	0.08
chr17_1655742_1656238	0.21	SERPINF1	serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1	9263	0.1
chr13_111827384_111827819	0.21	ARHGEF7	Rho guanine nucleotide exchange factor (GEF) 7	9684	0.21
chr22_38037451_38037808	0.21	SH3BP1	SH3-domain binding protein 1	158	0.91
chr9_19998614_19999028	0.21	ENSG00000266224	.	169070	0.03
chr19_588658_588919	0.21	HCN2	hyperpolarization activated cyclic nucleotide-gated potassium channel 2	1105	0.3
chr4_5709067_5709627	0.21	EVC2	Ellis van Creveld syndrome 2	947	0.61
chr2_38324502_38325000	0.21	CYP1B1-AS1	CYP1B1 antisense RNA 1	971	0.56
chr18_56279030_56279181	0.21	ENSG00000252284	.	11242	0.15
chr17_2162360_2162742	0.21	SMG6	SMG6 nonsense mediated mRNA decay factor	6874	0.12
chr17_4299470_4299621	0.21	UBE2G1	ubiquitin-conjugating enzyme E2G 1	29622	0.12
chr1_68190930_68191081	0.21	GADD45A	growth arrest and DNA-damage-inducible, alpha	40121	0.15
chr1_22441481_22441632	0.21	WNT4	wingless-type MMTV integration site family, member 4	14788	0.17
chr5_124895396_124895838	0.21	ENSG00000222107	.	208793	0.03
chr18_43927955_43928106	0.21	RNF165	ring finger protein 165	13843	0.27
chr10_72253009_72253304	0.21	PALD1	phosphatase domain containing, paladin 1	14579	0.19
chr16_67994185_67994336	0.21	SLC12A4	solute carrier family 12 (potassium/chloride transporter), member 4	3708	0.1
chr9_86916540_86916691	0.21	RP11-380F14.2		23481	0.22
chr3_42531570_42531721	0.21	VIPR1	vasoactive intestinal peptide receptor 1	854	0.59
chr5_134996744_134996895	0.21	ENSG00000238393	.	52086	0.12
chr10_120997309_120997844	0.21	ENSG00000242853	.	25207	0.13
chr1_205568177_205568328	0.21	ENSG00000206762	.	4083	0.18
chr10_111655218_111655499	0.21	XPNPEP1	X-prolyl aminopeptidase (aminopeptidase P) 1, soluble	12219	0.21
chr11_82617435_82617696	0.21	C11orf82	chromosome 11 open reading frame 82	2735	0.27
chr2_237677835_237677986	0.21	ACKR3	atypical chemokine receptor 3	199626	0.03
chr1_27849324_27849766	0.21	RP1-159A19.4		2771	0.25
chr8_27472453_27472699	0.21	CLU	clusterin	28	0.98
chr7_44419516_44419667	0.20	CAMK2B	calcium/calmodulin-dependent protein kinase II beta	54336	0.12
chr9_130283553_130283704	0.20	FAM129B	family with sequence similarity 129, member B	47739	0.09
chr6_7059032_7059265	0.20	ENSG00000251762	.	18369	0.22
chr19_41729675_41729826	0.20	CTD-2195B23.3		1794	0.23
chr1_212643207_212643358	0.20	NENF	neudesin neurotrophic factor	37053	0.14
chr14_100003657_100003808	0.20	CCDC85C	coiled-coil domain containing 85C	1307	0.41
chr8_21989039_21989190	0.20	HR	hair growth associated	267	0.85
chr11_86236038_86236189	0.20	ME3	malic enzyme 3, NADP(+)-dependent, mitochondrial	34749	0.2

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of SMAD4

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	0.7	GO:0044415	evasion or tolerance of host defenses by virus(GO:0019049) avoidance of host defenses(GO:0044413) evasion or tolerance of host defenses(GO:0044415) avoidance of defenses of other organism involved in symbiotic interaction(GO:0051832) evasion or tolerance of defenses of other organism involved in symbiotic interaction(GO:0051834)
0.2	0.5	GO:0010757	negative regulation of plasminogen activation(GO:0010757)
0.1	0.4	GO:0010511	regulation of phosphatidylinositol biosynthetic process(GO:0010511)
0.1	0.3	GO:0051152	positive regulation of smooth muscle cell differentiation(GO:0051152)
0.1	0.5	GO:0070141	response to UV-A(GO:0070141)
0.1	0.4	GO:0070295	renal water absorption(GO:0070295)
0.1	0.6	GO:0030579	ubiquitin-dependent SMAD protein catabolic process(GO:0030579)
0.1	0.1	GO:0060523	prostate epithelial cord elongation(GO:0060523)
0.1	0.8	GO:0060037	pharyngeal system development(GO:0060037)
0.1	0.3	GO:0060831	smoothened signaling pathway involved in dorsal/ventral neural tube patterning(GO:0060831)
0.1	0.1	GO:0060737	prostate gland morphogenetic growth(GO:0060737)
0.1	0.3	GO:0032353	negative regulation of hormone metabolic process(GO:0032351) negative regulation of hormone biosynthetic process(GO:0032353)
0.1	0.4	GO:0032808	lacrimal gland development(GO:0032808)
0.1	0.1	GO:0030835	negative regulation of actin filament depolymerization(GO:0030835)
0.1	0.1	GO:2000041	regulation of planar cell polarity pathway involved in axis elongation(GO:2000040) negative regulation of planar cell polarity pathway involved in axis elongation(GO:2000041)
0.1	0.3	GO:0072201	negative regulation of mesenchymal cell proliferation(GO:0072201)
0.1	0.4	GO:0060666	dichotomous subdivision of terminal units involved in salivary gland branching(GO:0060666)
0.1	0.3	GO:0000212	meiotic spindle organization(GO:0000212)
0.1	0.3	GO:0010766	negative regulation of sodium ion transport(GO:0010766)
0.1	0.6	GO:0048013	ephrin receptor signaling pathway(GO:0048013)
0.1	0.3	GO:0090400	stress-induced premature senescence(GO:0090400)
0.1	0.3	GO:0071681	response to indole-3-methanol(GO:0071680) cellular response to indole-3-methanol(GO:0071681)
0.1	0.3	GO:0042268	regulation of cytolysis(GO:0042268)
0.1	0.3	GO:0016103	diterpenoid catabolic process(GO:0016103) terpenoid catabolic process(GO:0016115) retinoic acid catabolic process(GO:0034653)
0.1	0.3	GO:0043589	skin morphogenesis(GO:0043589)
0.1	0.2	GO:0035385	Roundabout signaling pathway(GO:0035385)
0.1	0.3	GO:0014012	peripheral nervous system axon regeneration(GO:0014012)
0.1	0.1	GO:0070099	regulation of chemokine-mediated signaling pathway(GO:0070099) negative regulation of chemokine-mediated signaling pathway(GO:0070100)
0.1	0.2	GO:0060346	bone trabecula formation(GO:0060346) bone trabecula morphogenesis(GO:0061430)
0.1	0.2	GO:0032693	negative regulation of interleukin-10 production(GO:0032693)
0.1	0.2	GO:0060605	tube lumen cavitation(GO:0060605) salivary gland cavitation(GO:0060662)
0.1	0.2	GO:0060433	bronchus development(GO:0060433)
0.1	0.2	GO:0021798	forebrain dorsal/ventral pattern formation(GO:0021798)
0.1	0.3	GO:0043497	regulation of protein heterodimerization activity(GO:0043497)
0.1	0.3	GO:0090190	positive regulation of mesonephros development(GO:0061213) positive regulation of branching involved in ureteric bud morphogenesis(GO:0090190)
0.1	0.4	GO:0090205	positive regulation of cholesterol metabolic process(GO:0090205)
0.1	0.4	GO:0010719	negative regulation of epithelial to mesenchymal transition(GO:0010719)
0.1	0.2	GO:1900115	sequestering of extracellular ligand from receptor(GO:0035581) sequestering of TGFbeta in extracellular matrix(GO:0035583) protein localization to extracellular region(GO:0071692) maintenance of protein location in extracellular region(GO:0071694) extracellular regulation of signal transduction(GO:1900115) extracellular negative regulation of signal transduction(GO:1900116)
0.1	0.2	GO:0060013	righting reflex(GO:0060013)
0.1	0.2	GO:0010193	response to ozone(GO:0010193)
0.1	0.1	GO:0061298	retina vasculature development in camera-type eye(GO:0061298) retina vasculature morphogenesis in camera-type eye(GO:0061299)
0.1	0.3	GO:0048096	chromatin-mediated maintenance of transcription(GO:0048096)
0.1	0.1	GO:0045198	polarized epithelial cell differentiation(GO:0030859) establishment of epithelial cell apical/basal polarity(GO:0045198)
0.1	0.2	GO:0050703	interleukin-1 alpha secretion(GO:0050703)
0.1	0.2	GO:0070837	dehydroascorbic acid transport(GO:0070837)
0.1	0.2	GO:1904747	apoptotic process involved in mammary gland involution(GO:0060057) positive regulation of apoptotic process involved in mammary gland involution(GO:0060058) positive regulation of apoptotic process involved in morphogenesis(GO:1902339) regulation of mammary gland involution(GO:1903519) positive regulation of mammary gland involution(GO:1903521) positive regulation of apoptotic process involved in development(GO:1904747)
0.1	0.3	GO:0014819	regulation of skeletal muscle contraction(GO:0014819)
0.1	0.4	GO:0060390	regulation of SMAD protein import into nucleus(GO:0060390)
0.1	0.2	GO:0000089	mitotic metaphase(GO:0000089)
0.1	0.1	GO:0045715	negative regulation of low-density lipoprotein particle receptor biosynthetic process(GO:0045715)
0.1	0.2	GO:0006562	proline catabolic process(GO:0006562)
0.1	0.2	GO:0021563	glossopharyngeal nerve development(GO:0021563) glossopharyngeal nerve morphogenesis(GO:0021615)
0.1	0.1	GO:0014045	establishment of endothelial blood-brain barrier(GO:0014045) central nervous system vasculogenesis(GO:0022009)
0.1	0.2	GO:0018242	protein O-linked glycosylation via serine(GO:0018242) protein O-linked glycosylation via threonine(GO:0018243)
0.1	0.2	GO:0071364	cellular response to epidermal growth factor stimulus(GO:0071364)
0.1	0.2	GO:0046185	aldehyde catabolic process(GO:0046185)
0.1	0.1	GO:0051541	elastin metabolic process(GO:0051541)
0.1	0.1	GO:0002043	blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:0002043)
0.1	0.2	GO:0060501	positive regulation of epithelial cell proliferation involved in lung morphogenesis(GO:0060501) epithelial cell proliferation involved in lung morphogenesis(GO:0060502) regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000794)
0.1	0.2	GO:0043173	nucleotide salvage(GO:0043173)
0.1	0.1	GO:0045077	negative regulation of interferon-gamma biosynthetic process(GO:0045077)
0.1	0.1	GO:0007144	female meiosis I(GO:0007144)
0.1	0.4	GO:0032462	regulation of protein homooligomerization(GO:0032462)
0.1	0.1	GO:0033688	regulation of osteoblast proliferation(GO:0033688)
0.1	0.5	GO:0007016	cytoskeletal anchoring at plasma membrane(GO:0007016)
0.1	0.2	GO:0042415	norepinephrine metabolic process(GO:0042415)
0.1	0.3	GO:0003254	regulation of membrane depolarization(GO:0003254)
0.1	0.1	GO:0036336	dendritic cell chemotaxis(GO:0002407) dendritic cell migration(GO:0036336)
0.1	0.1	GO:0008300	isoprenoid catabolic process(GO:0008300)
0.1	0.1	GO:0010803	regulation of tumor necrosis factor-mediated signaling pathway(GO:0010803)
0.1	0.1	GO:0045662	negative regulation of myoblast differentiation(GO:0045662)
0.1	0.2	GO:0006296	nucleotide-excision repair, DNA incision, 5'-to lesion(GO:0006296)
0.1	0.2	GO:0090073	positive regulation of protein homodimerization activity(GO:0090073)
0.1	0.1	GO:0051176	positive regulation of sulfur metabolic process(GO:0051176)
0.1	1.1	GO:0045103	intermediate filament-based process(GO:0045103)
0.1	0.2	GO:0042670	retinal cone cell differentiation(GO:0042670) retinal cone cell development(GO:0046549)
0.1	0.2	GO:0045898	regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045898)
0.1	0.2	GO:0046813	receptor-mediated virion attachment to host cell(GO:0046813)
0.1	0.1	GO:0060343	trabecula formation(GO:0060343) trabecula morphogenesis(GO:0061383)
0.1	0.2	GO:0048799	organ maturation(GO:0048799) bone maturation(GO:0070977)
0.1	0.2	GO:0015864	pyrimidine nucleoside transport(GO:0015864)
0.1	0.1	GO:0071378	growth hormone receptor signaling pathway(GO:0060396) cellular response to growth hormone stimulus(GO:0071378)
0.1	0.1	GO:0051882	mitochondrial depolarization(GO:0051882)
0.1	0.1	GO:0060129	thyroid-stimulating hormone-secreting cell differentiation(GO:0060129)
0.1	0.1	GO:0060044	negative regulation of cardiac muscle tissue growth(GO:0055022) negative regulation of cardiac muscle tissue development(GO:0055026) negative regulation of cardiac muscle cell proliferation(GO:0060044) negative regulation of heart growth(GO:0061117)
0.1	0.2	GO:0043276	anoikis(GO:0043276)
0.1	0.2	GO:0001574	ganglioside biosynthetic process(GO:0001574)
0.1	0.6	GO:0060612	adipose tissue development(GO:0060612)
0.1	0.6	GO:0035329	hippo signaling(GO:0035329)
0.1	0.1	GO:0032461	positive regulation of protein oligomerization(GO:0032461)
0.1	0.3	GO:0005981	regulation of glycogen catabolic process(GO:0005981)
0.1	0.1	GO:0051771	negative regulation of nitric-oxide synthase biosynthetic process(GO:0051771)
0.1	0.1	GO:0007191	adenylate cyclase-activating dopamine receptor signaling pathway(GO:0007191)
0.1	0.2	GO:0050916	sensory perception of sweet taste(GO:0050916)
0.1	0.3	GO:0021670	lateral ventricle development(GO:0021670)
0.1	0.2	GO:0001743	optic placode formation(GO:0001743)
0.1	0.3	GO:0042487	regulation of odontogenesis of dentin-containing tooth(GO:0042487)
0.1	0.2	GO:1905209	positive regulation of cardioblast differentiation(GO:0051891) positive regulation of cardiocyte differentiation(GO:1905209)
0.1	0.3	GO:0043922	negative regulation by host of viral transcription(GO:0043922)
0.1	0.5	GO:0031581	hemidesmosome assembly(GO:0031581)
0.1	0.1	GO:0021783	preganglionic parasympathetic fiber development(GO:0021783)
0.0	0.1	GO:0050917	sensory perception of umami taste(GO:0050917)
0.0	0.0	GO:0006106	fumarate metabolic process(GO:0006106)
0.0	0.8	GO:0048286	lung alveolus development(GO:0048286)
0.0	0.2	GO:0060707	trophoblast giant cell differentiation(GO:0060707)
0.0	0.1	GO:0018401	peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401) 4-hydroxyproline metabolic process(GO:0019471) peptidyl-proline hydroxylation(GO:0019511)
0.0	0.2	GO:0032288	myelin assembly(GO:0032288)
0.0	0.1	GO:0045617	negative regulation of keratinocyte differentiation(GO:0045617)
0.0	0.1	GO:0032469	endoplasmic reticulum calcium ion homeostasis(GO:0032469)
0.0	0.2	GO:0072383	plus-end-directed vesicle transport along microtubule(GO:0072383) plus-end-directed organelle transport along microtubule(GO:0072386)
0.0	0.1	GO:0033145	positive regulation of intracellular steroid hormone receptor signaling pathway(GO:0033145)
0.0	0.1	GO:1902803	regulation of synaptic vesicle transport(GO:1902803) regulation of synaptic vesicle exocytosis(GO:2000300)
0.0	0.2	GO:0051124	synaptic growth at neuromuscular junction(GO:0051124)
0.0	0.0	GO:0042118	endothelial cell activation(GO:0042118)
0.0	0.1	GO:0009169	purine nucleoside monophosphate catabolic process(GO:0009128) ribonucleoside monophosphate catabolic process(GO:0009158) purine ribonucleoside monophosphate catabolic process(GO:0009169)
0.0	0.1	GO:0016093	polyprenol metabolic process(GO:0016093) dolichol metabolic process(GO:0019348)
0.0	0.3	GO:0021527	spinal cord association neuron differentiation(GO:0021527)
0.0	0.5	GO:0048538	thymus development(GO:0048538)
0.0	0.1	GO:0060743	epithelial cell maturation involved in prostate gland development(GO:0060743)
0.0	0.1	GO:0097502	protein mannosylation(GO:0035268) protein O-linked mannosylation(GO:0035269) mannosylation(GO:0097502)
0.0	0.2	GO:0008634	obsolete negative regulation of survival gene product expression(GO:0008634)
0.0	0.2	GO:0014912	negative regulation of smooth muscle cell migration(GO:0014912)
0.0	0.1	GO:0032060	bleb assembly(GO:0032060)
0.0	0.1	GO:0071294	cellular response to zinc ion(GO:0071294)
0.0	0.4	GO:0007520	myoblast fusion(GO:0007520)
0.0	0.3	GO:0032276	regulation of gonadotropin secretion(GO:0032276)
0.0	0.4	GO:0045725	positive regulation of glycogen biosynthetic process(GO:0045725)
0.0	0.0	GO:0061072	iris morphogenesis(GO:0061072)
0.0	0.1	GO:0003010	voluntary skeletal muscle contraction(GO:0003010) twitch skeletal muscle contraction(GO:0014721)
0.0	0.0	GO:0031579	membrane raft organization(GO:0031579)
0.0	0.2	GO:0043985	histone H4-R3 methylation(GO:0043985)
0.0	0.1	GO:1903332	regulation of protein folding(GO:1903332)
0.0	0.2	GO:0001866	NK T cell proliferation(GO:0001866)
0.0	0.3	GO:0033483	gas homeostasis(GO:0033483)
0.0	0.1	GO:0060841	venous blood vessel development(GO:0060841)
0.0	0.3	GO:0034331	cell junction maintenance(GO:0034331) cellular component maintenance(GO:0043954) cell-cell junction maintenance(GO:0045217)
0.0	0.2	GO:1902668	negative regulation of axon guidance(GO:1902668)
0.0	0.2	GO:0006564	L-serine biosynthetic process(GO:0006564)
0.0	0.2	GO:0048668	collateral sprouting(GO:0048668)
0.0	0.0	GO:0072161	mesenchymal cell differentiation involved in kidney development(GO:0072161) metanephric mesenchymal cell differentiation(GO:0072162) mesenchymal cell differentiation involved in renal system development(GO:2001012)
0.0	0.2	GO:0031282	regulation of guanylate cyclase activity(GO:0031282)
0.0	0.1	GO:0046548	retinal rod cell development(GO:0046548)
0.0	0.1	GO:0014820	tonic smooth muscle contraction(GO:0014820) artery smooth muscle contraction(GO:0014824)
0.0	0.2	GO:0045197	establishment or maintenance of epithelial cell apical/basal polarity(GO:0045197)
0.0	0.1	GO:0048388	endosomal lumen acidification(GO:0048388)
0.0	0.2	GO:0061004	pattern specification involved in kidney development(GO:0061004) renal system pattern specification(GO:0072048) pattern specification involved in metanephros development(GO:0072268)
0.0	0.2	GO:0015889	cobalamin transport(GO:0015889)
0.0	0.1	GO:0040016	embryonic cleavage(GO:0040016)
0.0	0.1	GO:0060762	regulation of branching involved in mammary gland duct morphogenesis(GO:0060762)
0.0	0.1	GO:0030309	poly-N-acetyllactosamine metabolic process(GO:0030309)
0.0	0.0	GO:0071459	protein localization to chromosome, centromeric region(GO:0071459)
0.0	0.3	GO:0032373	positive regulation of sterol transport(GO:0032373) positive regulation of cholesterol transport(GO:0032376)
0.0	0.2	GO:0048172	regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.0	0.1	GO:0045007	depurination(GO:0045007)
0.0	0.1	GO:0090047	obsolete positive regulation of transcription regulator activity(GO:0090047)
0.0	0.1	GO:0097709	connective tissue replacement involved in inflammatory response wound healing(GO:0002248) connective tissue replacement(GO:0097709)
0.0	0.6	GO:0009267	cellular response to starvation(GO:0009267)
0.0	0.1	GO:0015820	branched-chain amino acid transport(GO:0015803) leucine transport(GO:0015820)
0.0	0.4	GO:0018214	peptidyl-glutamic acid carboxylation(GO:0017187) protein carboxylation(GO:0018214)
0.0	0.1	GO:0016081	synaptic vesicle docking(GO:0016081)
0.0	0.0	GO:0060061	Spemann organizer formation(GO:0060061)
0.0	0.2	GO:0006533	aspartate metabolic process(GO:0006531) aspartate catabolic process(GO:0006533)
0.0	0.0	GO:0032927	positive regulation of activin receptor signaling pathway(GO:0032927)
0.0	0.2	GO:0035020	regulation of Rac protein signal transduction(GO:0035020)
0.0	0.1	GO:0021570	rhombomere 4 development(GO:0021570)
0.0	0.1	GO:0060539	diaphragm development(GO:0060539)
0.0	0.1	GO:0032674	interleukin-5 production(GO:0032634) regulation of interleukin-5 production(GO:0032674)
0.0	0.1	GO:0042640	anagen(GO:0042640)
0.0	0.1	GO:0021999	neural plate anterior/posterior regionalization(GO:0021999) neural plate regionalization(GO:0060897)
0.0	0.1	GO:0071816	protein insertion into ER membrane(GO:0045048) tail-anchored membrane protein insertion into ER membrane(GO:0071816)
0.0	0.1	GO:0009215	purine deoxyribonucleoside triphosphate metabolic process(GO:0009215)
0.0	0.1	GO:0048312	intracellular distribution of mitochondria(GO:0048312)
0.0	0.1	GO:0014848	urinary bladder smooth muscle contraction(GO:0014832) urinary tract smooth muscle contraction(GO:0014848)
0.0	0.1	GO:0045836	positive regulation of meiotic nuclear division(GO:0045836) positive regulation of meiotic cell cycle(GO:0051446)
0.0	0.0	GO:0015824	proline transport(GO:0015824)
0.0	0.1	GO:0043578	nuclear matrix organization(GO:0043578) nuclear matrix anchoring at nuclear membrane(GO:0090292)
0.0	0.1	GO:0042271	susceptibility to natural killer cell mediated cytotoxicity(GO:0042271)
0.0	0.1	GO:0060014	granulosa cell differentiation(GO:0060014)
0.0	0.1	GO:0044314	protein K27-linked ubiquitination(GO:0044314)
0.0	0.1	GO:0071502	cellular response to temperature stimulus(GO:0071502)
0.0	0.2	GO:0051150	regulation of smooth muscle cell differentiation(GO:0051150)
0.0	0.1	GO:0033962	cytoplasmic mRNA processing body assembly(GO:0033962)
0.0	0.1	GO:0019367	fatty acid elongation, saturated fatty acid(GO:0019367)
0.0	0.1	GO:0006384	transcription initiation from RNA polymerase III promoter(GO:0006384)
0.0	0.1	GO:0010887	negative regulation of cholesterol storage(GO:0010887)
0.0	0.2	GO:0070670	response to interleukin-4(GO:0070670)
0.0	0.0	GO:0033091	positive regulation of immature T cell proliferation(GO:0033091)
0.0	0.0	GO:0034969	histone arginine methylation(GO:0034969)
0.0	0.1	GO:0051497	negative regulation of stress fiber assembly(GO:0051497)
0.0	0.1	GO:0060081	membrane hyperpolarization(GO:0060081)
0.0	0.1	GO:0048702	embryonic neurocranium morphogenesis(GO:0048702)
0.0	0.1	GO:0021937	cerebellar Purkinje cell-granule cell precursor cell signaling involved in regulation of granule cell precursor cell proliferation(GO:0021937)
0.0	0.2	GO:0016246	RNA interference(GO:0016246)
0.0	0.1	GO:0031117	positive regulation of microtubule depolymerization(GO:0031117)
0.0	0.0	GO:0048859	formation of anatomical boundary(GO:0048859)
0.0	0.1	GO:0040015	negative regulation of multicellular organism growth(GO:0040015)
0.0	0.2	GO:0009404	toxin metabolic process(GO:0009404)
0.0	0.2	GO:0006398	mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398)
0.0	0.2	GO:0006646	phosphatidylethanolamine biosynthetic process(GO:0006646) phosphatidylethanolamine metabolic process(GO:0046337)
0.0	0.1	GO:0090084	negative regulation of inclusion body assembly(GO:0090084)
0.0	0.3	GO:0034453	microtubule anchoring(GO:0034453)
0.0	0.1	GO:0021546	rhombomere development(GO:0021546)
0.0	0.1	GO:0032527	retrograde protein transport, ER to cytosol(GO:0030970) protein exit from endoplasmic reticulum(GO:0032527)
0.0	0.0	GO:0070059	intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress(GO:0070059)
0.0	0.1	GO:0010815	bradykinin catabolic process(GO:0010815)
0.0	0.1	GO:0048643	positive regulation of skeletal muscle tissue development(GO:0048643)
0.0	0.1	GO:0021904	dorsal/ventral neural tube patterning(GO:0021904)
0.0	0.1	GO:0031507	heterochromatin assembly(GO:0031507) heterochromatin organization(GO:0070828)
0.0	0.0	GO:0060684	epithelial-mesenchymal cell signaling(GO:0060684)
0.0	0.1	GO:0031340	regulation of vesicle fusion(GO:0031338) positive regulation of vesicle fusion(GO:0031340)
0.0	0.0	GO:0007598	blood coagulation, extrinsic pathway(GO:0007598)
0.0	0.0	GO:0061077	chaperone-mediated protein folding(GO:0061077)
0.0	0.1	GO:0001757	somite specification(GO:0001757)
0.0	0.6	GO:0007566	embryo implantation(GO:0007566)
0.0	0.1	GO:0006855	drug transmembrane transport(GO:0006855)
0.0	0.1	GO:0034063	stress granule assembly(GO:0034063)
0.0	0.1	GO:0060317	cardiac epithelial to mesenchymal transition(GO:0060317)
0.0	0.2	GO:0051597	response to methylmercury(GO:0051597)
0.0	0.0	GO:0045541	negative regulation of cholesterol biosynthetic process(GO:0045541) negative regulation of cholesterol metabolic process(GO:0090206)
0.0	0.0	GO:0048149	behavioral response to ethanol(GO:0048149)
0.0	0.1	GO:0045989	positive regulation of striated muscle contraction(GO:0045989)
0.0	0.4	GO:0001958	endochondral ossification(GO:0001958) replacement ossification(GO:0036075)
0.0	0.1	GO:0090177	establishment of planar polarity involved in neural tube closure(GO:0090177)
0.0	0.0	GO:0050765	negative regulation of phagocytosis(GO:0050765)
0.0	0.4	GO:0038061	activation of NF-kappaB-inducing kinase activity(GO:0007250) NIK/NF-kappaB signaling(GO:0038061) regulation of NIK/NF-kappaB signaling(GO:1901222) positive regulation of NIK/NF-kappaB signaling(GO:1901224)
0.0	0.1	GO:0006420	arginyl-tRNA aminoacylation(GO:0006420)
0.0	0.1	GO:0032801	receptor catabolic process(GO:0032801)
0.0	0.2	GO:0006975	DNA damage induced protein phosphorylation(GO:0006975)
0.0	0.1	GO:0014850	response to muscle activity(GO:0014850)
0.0	0.1	GO:0001973	adenosine receptor signaling pathway(GO:0001973) G-protein coupled purinergic receptor signaling pathway(GO:0035588)
0.0	0.2	GO:0006020	inositol metabolic process(GO:0006020)
0.0	0.1	GO:0048289	isotype switching to IgE isotypes(GO:0048289) regulation of isotype switching to IgE isotypes(GO:0048293)
0.0	0.0	GO:0046952	ketone body catabolic process(GO:0046952)
0.0	0.0	GO:0060839	endothelial cell fate commitment(GO:0060839)
0.0	0.4	GO:0042491	auditory receptor cell differentiation(GO:0042491)
0.0	0.1	GO:0044803	multi-organism membrane organization(GO:0044803)
0.0	0.1	GO:0048548	regulation of pinocytosis(GO:0048548)
0.0	0.1	GO:0060770	epithelial cell proliferation involved in prostate gland development(GO:0060767) regulation of epithelial cell proliferation involved in prostate gland development(GO:0060768) negative regulation of epithelial cell proliferation involved in prostate gland development(GO:0060770)
0.0	0.0	GO:0060992	response to fungicide(GO:0060992)
0.0	0.1	GO:0008054	negative regulation of cyclin-dependent protein serine/threonine kinase by cyclin degradation(GO:0008054)
0.0	0.1	GO:0010225	response to UV-C(GO:0010225)
0.0	0.1	GO:0046628	positive regulation of insulin receptor signaling pathway(GO:0046628) positive regulation of cellular response to insulin stimulus(GO:1900078)
0.0	0.3	GO:0032456	endocytic recycling(GO:0032456)
0.0	0.1	GO:0033137	negative regulation of peptidyl-serine phosphorylation(GO:0033137)
0.0	0.1	GO:0006290	pyrimidine dimer repair(GO:0006290)
0.0	0.2	GO:0015074	DNA integration(GO:0015074)
0.0	0.1	GO:0000966	RNA 5'-end processing(GO:0000966)
0.0	0.1	GO:0014741	negative regulation of cardiac muscle hypertrophy(GO:0010614) negative regulation of muscle hypertrophy(GO:0014741)
0.0	0.4	GO:0030520	intracellular estrogen receptor signaling pathway(GO:0030520)
0.0	0.0	GO:0010871	negative regulation of receptor biosynthetic process(GO:0010871)
0.0	0.1	GO:0071277	cellular response to calcium ion(GO:0071277)
0.0	0.1	GO:0042249	establishment of planar polarity of embryonic epithelium(GO:0042249)
0.0	0.1	GO:0051182	coenzyme transport(GO:0051182)
0.0	0.1	GO:0050965	detection of temperature stimulus involved in sensory perception(GO:0050961) detection of temperature stimulus involved in sensory perception of pain(GO:0050965)
0.0	0.1	GO:0043113	receptor clustering(GO:0043113)
0.0	0.0	GO:0061154	endothelial tube morphogenesis(GO:0061154)
0.0	0.3	GO:1902749	regulation of G2/M transition of mitotic cell cycle(GO:0010389) regulation of cell cycle G2/M phase transition(GO:1902749)
0.0	0.1	GO:0060023	soft palate development(GO:0060023)
0.0	0.0	GO:0060397	JAK-STAT cascade involved in growth hormone signaling pathway(GO:0060397)
0.0	0.1	GO:0042637	catagen(GO:0042637)
0.0	0.0	GO:0044380	protein localization to cytoskeleton(GO:0044380) protein localization to microtubule cytoskeleton(GO:0072698)
0.0	0.1	GO:0007184	SMAD protein import into nucleus(GO:0007184)
0.0	0.1	GO:0015812	gamma-aminobutyric acid transport(GO:0015812)
0.0	0.0	GO:0048263	determination of dorsal identity(GO:0048263)
0.0	0.1	GO:0007440	foregut morphogenesis(GO:0007440)
0.0	0.1	GO:0008614	pyridoxine metabolic process(GO:0008614) pyridoxine biosynthetic process(GO:0008615) vitamin B6 metabolic process(GO:0042816) vitamin B6 biosynthetic process(GO:0042819)
0.0	0.3	GO:0006386	transcription elongation from RNA polymerase III promoter(GO:0006385) termination of RNA polymerase III transcription(GO:0006386)
0.0	0.2	GO:0007185	transmembrane receptor protein tyrosine phosphatase signaling pathway(GO:0007185)
0.0	0.1	GO:0042977	activation of JAK2 kinase activity(GO:0042977)
0.0	0.1	GO:0032467	positive regulation of cytokinesis(GO:0032467)
0.0	0.2	GO:0007528	neuromuscular junction development(GO:0007528)
0.0	0.1	GO:0034501	protein localization to kinetochore(GO:0034501)
0.0	0.2	GO:0043537	negative regulation of blood vessel endothelial cell migration(GO:0043537)
0.0	0.7	GO:0030837	negative regulation of actin filament polymerization(GO:0030837)
0.0	0.1	GO:0042921	glucocorticoid receptor signaling pathway(GO:0042921)
0.0	0.1	GO:0051503	adenine nucleotide transport(GO:0051503)
0.0	0.0	GO:0010002	cardioblast differentiation(GO:0010002)
0.0	0.1	GO:0006048	UDP-N-acetylglucosamine biosynthetic process(GO:0006048)
0.0	0.2	GO:0007216	G-protein coupled glutamate receptor signaling pathway(GO:0007216)
0.0	0.1	GO:0032341	aldosterone metabolic process(GO:0032341) aldosterone biosynthetic process(GO:0032342)
0.0	0.1	GO:0009200	deoxyribonucleoside triphosphate metabolic process(GO:0009200)
0.0	0.1	GO:0070272	proton-transporting ATP synthase complex assembly(GO:0043461) proton-transporting ATP synthase complex biogenesis(GO:0070272)
0.0	1.2	GO:0051291	protein heterooligomerization(GO:0051291)
0.0	0.2	GO:0017158	regulation of calcium ion-dependent exocytosis(GO:0017158)
0.0	0.2	GO:0007217	tachykinin receptor signaling pathway(GO:0007217)
0.0	0.2	GO:0018065	protein-cofactor linkage(GO:0018065)
0.0	0.3	GO:0051492	regulation of stress fiber assembly(GO:0051492)
0.0	0.0	GO:0010989	negative regulation of low-density lipoprotein particle clearance(GO:0010989)
0.0	0.1	GO:0072216	positive regulation of metanephros development(GO:0072216)
0.0	0.7	GO:0003333	amino acid transmembrane transport(GO:0003333)
0.0	0.2	GO:0006002	fructose 6-phosphate metabolic process(GO:0006002)
0.0	0.1	GO:0051145	smooth muscle cell differentiation(GO:0051145)
0.0	0.0	GO:0021694	cerebellar Purkinje cell layer morphogenesis(GO:0021692) cerebellar Purkinje cell layer formation(GO:0021694) cerebellar Purkinje cell differentiation(GO:0021702)
0.0	0.2	GO:0007567	parturition(GO:0007567)
0.0	0.0	GO:0042996	regulation of Golgi to plasma membrane protein transport(GO:0042996)
0.0	0.0	GO:0048241	negative regulation of epinephrine secretion(GO:0032811) epinephrine transport(GO:0048241) epinephrine secretion(GO:0048242)
0.0	0.2	GO:0008347	glial cell migration(GO:0008347)
0.0	0.1	GO:0098810	neurotransmitter reuptake(GO:0098810)
0.0	0.2	GO:0043545	Mo-molybdopterin cofactor biosynthetic process(GO:0006777) Mo-molybdopterin cofactor metabolic process(GO:0019720) molybdopterin cofactor biosynthetic process(GO:0032324) molybdopterin cofactor metabolic process(GO:0043545) prosthetic group metabolic process(GO:0051189)
0.0	0.2	GO:0001662	behavioral fear response(GO:0001662)
0.0	0.0	GO:0022417	protein maturation by protein folding(GO:0022417)
0.0	0.1	GO:0006346	methylation-dependent chromatin silencing(GO:0006346)
0.0	0.0	GO:0061028	establishment of endothelial barrier(GO:0061028)
0.0	0.3	GO:0035194	posttranscriptional gene silencing(GO:0016441) posttranscriptional gene silencing by RNA(GO:0035194)
0.0	0.1	GO:0018106	peptidyl-histidine phosphorylation(GO:0018106)
0.0	0.0	GO:0050435	beta-amyloid metabolic process(GO:0050435)
0.0	0.2	GO:0051322	anaphase(GO:0051322)
0.0	0.0	GO:0048170	positive regulation of long-term neuronal synaptic plasticity(GO:0048170)
0.0	0.2	GO:0031268	pseudopodium organization(GO:0031268)
0.0	0.1	GO:0009296	obsolete flagellum assembly(GO:0009296)
0.0	0.6	GO:0000188	inactivation of MAPK activity(GO:0000188)
0.0	0.0	GO:0007418	ventral midline development(GO:0007418)
0.0	0.1	GO:0018206	peptidyl-methionine modification(GO:0018206)
0.0	0.1	GO:0003310	pancreatic A cell differentiation(GO:0003310)
0.0	0.0	GO:0007412	axon target recognition(GO:0007412)
0.0	0.1	GO:0002327	immature B cell differentiation(GO:0002327) pre-B cell differentiation(GO:0002329)
0.0	0.0	GO:0033240	positive regulation of cellular amine metabolic process(GO:0033240)
0.0	0.1	GO:0045793	positive regulation of cell size(GO:0045793)
0.0	0.2	GO:0009629	response to gravity(GO:0009629)
0.0	0.1	GO:0018101	protein citrullination(GO:0018101)
0.0	0.0	GO:0021924	cell proliferation in hindbrain(GO:0021534) cell proliferation in external granule layer(GO:0021924) cerebellar granule cell precursor proliferation(GO:0021930)
0.0	0.0	GO:0048861	leukemia inhibitory factor signaling pathway(GO:0048861)
0.0	0.1	GO:0009304	tRNA transcription(GO:0009304) 5S class rRNA transcription from RNA polymerase III type 1 promoter(GO:0042791) tRNA transcription from RNA polymerase III promoter(GO:0042797)
0.0	0.0	GO:0001831	trophectodermal cellular morphogenesis(GO:0001831)
0.0	0.1	GO:0043490	malate-aspartate shuttle(GO:0043490)
0.0	0.1	GO:0061088	regulation of sequestering of zinc ion(GO:0061088)
0.0	0.1	GO:0051552	flavone metabolic process(GO:0051552)
0.0	0.1	GO:0032020	ISG15-protein conjugation(GO:0032020)
0.0	0.1	GO:0039656	modulation by virus of host gene expression(GO:0039656)
0.0	0.1	GO:0010901	regulation of very-low-density lipoprotein particle remodeling(GO:0010901)
0.0	0.2	GO:0051927	obsolete negative regulation of calcium ion transport via voltage-gated calcium channel activity(GO:0051927)
0.0	0.0	GO:0032025	response to cobalt ion(GO:0032025)
0.0	0.0	GO:0048875	surfactant homeostasis(GO:0043129) chemical homeostasis within a tissue(GO:0048875)
0.0	0.1	GO:0008215	spermine metabolic process(GO:0008215)
0.0	0.0	GO:0002689	negative regulation of leukocyte chemotaxis(GO:0002689)
0.0	0.1	GO:0070389	chaperone cofactor-dependent protein refolding(GO:0070389)
0.0	0.0	GO:0090085	regulation of protein deubiquitination(GO:0090085)
0.0	0.1	GO:0042167	porphyrin-containing compound catabolic process(GO:0006787) tetrapyrrole catabolic process(GO:0033015) heme catabolic process(GO:0042167) pigment catabolic process(GO:0046149)
0.0	0.1	GO:0018343	protein farnesylation(GO:0018343)
0.0	0.2	GO:0006656	phosphatidylcholine biosynthetic process(GO:0006656)
0.0	0.2	GO:0006688	glycosphingolipid biosynthetic process(GO:0006688)
0.0	0.4	GO:0044349	nucleotide-excision repair, DNA damage removal(GO:0000718) DNA excision(GO:0044349)
0.0	0.1	GO:0030505	inorganic diphosphate transport(GO:0030505)
0.0	0.0	GO:0010700	negative regulation of norepinephrine secretion(GO:0010700)
0.0	0.1	GO:0046838	phosphorylated carbohydrate dephosphorylation(GO:0046838) inositol phosphate dephosphorylation(GO:0046855)
0.0	0.1	GO:0060236	regulation of mitotic spindle organization(GO:0060236)
0.0	0.1	GO:0040037	negative regulation of fibroblast growth factor receptor signaling pathway(GO:0040037)
0.0	0.0	GO:0006065	UDP-glucuronate biosynthetic process(GO:0006065)
0.0	0.1	GO:0007379	segment specification(GO:0007379)
0.0	0.0	GO:0071688	skeletal muscle myosin thick filament assembly(GO:0030241) myosin filament assembly(GO:0031034) striated muscle myosin thick filament assembly(GO:0071688)
0.0	0.0	GO:0034204	lipid translocation(GO:0034204) phospholipid translocation(GO:0045332)
0.0	0.1	GO:0006449	regulation of translational termination(GO:0006449)
0.0	0.0	GO:0060073	micturition(GO:0060073) synaptic transmission involved in micturition(GO:0060084)
0.0	0.1	GO:0019673	GDP-mannose metabolic process(GO:0019673)
0.0	0.0	GO:0007097	nuclear migration(GO:0007097)
0.0	0.1	GO:0045046	protein import into peroxisome membrane(GO:0045046)
0.0	0.1	GO:0010633	negative regulation of epithelial cell migration(GO:0010633)
0.0	0.2	GO:0098743	cartilage condensation(GO:0001502) cell aggregation(GO:0098743)
0.0	0.1	GO:0032516	positive regulation of phosphoprotein phosphatase activity(GO:0032516)
0.0	0.0	GO:0050862	positive regulation of T cell receptor signaling pathway(GO:0050862)
0.0	0.3	GO:0008038	neuron recognition(GO:0008038)
0.0	0.2	GO:0030148	sphingolipid biosynthetic process(GO:0030148)
0.0	0.1	GO:0032055	negative regulation of translation in response to stress(GO:0032055) negative regulation of translational initiation in response to stress(GO:0032057)
0.0	0.0	GO:2000104	negative regulation of DNA-dependent DNA replication(GO:2000104)
0.0	0.0	GO:0007571	age-dependent response to oxidative stress(GO:0001306) age-dependent general metabolic decline(GO:0007571)
0.0	0.1	GO:0046339	diacylglycerol metabolic process(GO:0046339)
0.0	0.0	GO:0043518	negative regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043518) negative regulation of signal transduction by p53 class mediator(GO:1901797)
0.0	0.2	GO:0021772	olfactory bulb development(GO:0021772)
0.0	0.0	GO:0042501	serine phosphorylation of STAT protein(GO:0042501)
0.0	0.0	GO:0048711	positive regulation of astrocyte differentiation(GO:0048711)
0.0	0.1	GO:0009180	ADP biosynthetic process(GO:0006172) purine nucleoside diphosphate biosynthetic process(GO:0009136) purine ribonucleoside diphosphate biosynthetic process(GO:0009180) ribonucleoside diphosphate biosynthetic process(GO:0009188)
0.0	0.1	GO:0006448	regulation of translational elongation(GO:0006448)
0.0	0.3	GO:0030199	collagen fibril organization(GO:0030199)
0.0	0.1	GO:0008291	acetylcholine metabolic process(GO:0008291) acetate ester metabolic process(GO:1900619)
0.0	0.1	GO:0045823	positive regulation of heart contraction(GO:0045823)
0.0	0.2	GO:0050771	negative regulation of axonogenesis(GO:0050771)
0.0	0.1	GO:0006269	DNA replication, synthesis of RNA primer(GO:0006269)
0.0	0.0	GO:0008295	spermidine biosynthetic process(GO:0008295)
0.0	0.1	GO:0048240	sperm capacitation(GO:0048240)
0.0	0.0	GO:0006166	purine ribonucleoside salvage(GO:0006166)
0.0	0.1	GO:0000460	maturation of 5.8S rRNA(GO:0000460)
0.0	0.0	GO:0046931	pore complex assembly(GO:0046931)
0.0	0.2	GO:0045776	negative regulation of blood pressure(GO:0045776)
0.0	0.0	GO:0048715	negative regulation of oligodendrocyte differentiation(GO:0048715)
0.0	0.1	GO:0070934	CRD-mediated mRNA stabilization(GO:0070934)
0.0	0.1	GO:0045880	positive regulation of smoothened signaling pathway(GO:0045880)
0.0	0.1	GO:0043526	obsolete neuroprotection(GO:0043526)
0.0	0.2	GO:0001738	morphogenesis of a polarized epithelium(GO:0001738)
0.0	0.2	GO:0008210	estrogen metabolic process(GO:0008210)
0.0	0.0	GO:0031116	positive regulation of microtubule polymerization(GO:0031116)
0.0	0.1	GO:0006663	platelet activating factor biosynthetic process(GO:0006663)
0.0	0.4	GO:0016338	calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.0	0.1	GO:0019800	peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.0	0.0	GO:0001560	regulation of cell growth by extracellular stimulus(GO:0001560)
0.0	0.1	GO:0006729	tetrahydrobiopterin biosynthetic process(GO:0006729)
0.0	0.2	GO:0007613	memory(GO:0007613)
0.0	0.1	GO:0006600	creatine metabolic process(GO:0006600)
0.0	0.1	GO:0006108	malate metabolic process(GO:0006108)
0.0	0.1	GO:0070634	transepithelial ammonium transport(GO:0070634)
0.0	0.1	GO:0045806	negative regulation of endocytosis(GO:0045806)
0.0	0.0	GO:0010040	response to iron(II) ion(GO:0010040)
0.0	0.0	GO:0032825	regulation of natural killer cell differentiation(GO:0032823) positive regulation of natural killer cell differentiation(GO:0032825)
0.0	0.0	GO:0021520	spinal cord motor neuron cell fate specification(GO:0021520)
0.0	0.1	GO:0043268	positive regulation of potassium ion transport(GO:0043268)
0.0	0.1	GO:0035024	negative regulation of Rho protein signal transduction(GO:0035024)
0.0	0.0	GO:0090036	regulation of protein kinase C signaling(GO:0090036) positive regulation of protein kinase C signaling(GO:0090037)
0.0	0.0	GO:0034723	DNA replication-dependent nucleosome organization(GO:0034723)
0.0	0.0	GO:0090162	establishment of epithelial cell polarity(GO:0090162)
0.0	0.1	GO:0014821	phasic smooth muscle contraction(GO:0014821)
0.0	0.1	GO:0019388	galactose catabolic process(GO:0019388)
0.0	0.1	GO:0017000	antibiotic metabolic process(GO:0016999) antibiotic biosynthetic process(GO:0017000)
0.0	0.1	GO:0032784	regulation of DNA-templated transcription, elongation(GO:0032784)
0.0	0.1	GO:0035624	receptor transactivation(GO:0035624) epidermal growth factor-activated receptor transactivation by G-protein coupled receptor signaling pathway(GO:0035625)
0.0	0.1	GO:0006188	IMP biosynthetic process(GO:0006188) IMP metabolic process(GO:0046040)
0.0	0.0	GO:0001302	replicative cell aging(GO:0001302)
0.0	0.1	GO:0010092	specification of organ identity(GO:0010092)
0.0	0.1	GO:0006011	UDP-glucose metabolic process(GO:0006011)
0.0	0.0	GO:0034384	high-density lipoprotein particle clearance(GO:0034384)
0.0	0.0	GO:0000768	syncytium formation by plasma membrane fusion(GO:0000768)
0.0	0.4	GO:0006493	protein O-linked glycosylation(GO:0006493)
0.0	0.1	GO:0042462	eye photoreceptor cell development(GO:0042462)
0.0	0.1	GO:0043457	regulation of cellular respiration(GO:0043457)
0.0	0.1	GO:0043983	histone H4-K12 acetylation(GO:0043983)
0.0	0.1	GO:0030488	tRNA methylation(GO:0030488)
0.0	0.2	GO:0045773	positive regulation of axon extension(GO:0045773)
0.0	0.1	GO:0051647	nucleus localization(GO:0051647)
0.0	0.0	GO:0008612	peptidyl-lysine modification to peptidyl-hypusine(GO:0008612)
0.0	0.1	GO:0007256	activation of JNKK activity(GO:0007256)
0.0	0.1	GO:0043137	lagging strand elongation(GO:0006273) DNA replication, Okazaki fragment processing(GO:0033567) DNA replication, removal of RNA primer(GO:0043137)
0.0	0.0	GO:0006922	obsolete cleavage of lamin involved in execution phase of apoptosis(GO:0006922)
0.0	0.3	GO:0051668	localization within membrane(GO:0051668)
0.0	0.0	GO:0035426	extracellular matrix-cell signaling(GO:0035426)
0.0	0.1	GO:0008218	bioluminescence(GO:0008218)
0.0	0.0	GO:0032691	negative regulation of interleukin-1 beta production(GO:0032691)
0.0	0.1	GO:0014911	positive regulation of smooth muscle cell migration(GO:0014911)
0.0	0.1	GO:0016973	poly(A)+ mRNA export from nucleus(GO:0016973)
0.0	0.0	GO:0045792	negative regulation of cell size(GO:0045792)
0.0	0.1	GO:1900087	traversing start control point of mitotic cell cycle(GO:0007089) positive regulation of G1/S transition of mitotic cell cycle(GO:1900087) positive regulation of cell cycle G1/S phase transition(GO:1902808)
0.0	0.1	GO:0055003	cardiac myofibril assembly(GO:0055003)
0.0	0.0	GO:0010561	negative regulation of glycoprotein biosynthetic process(GO:0010561)
0.0	0.1	GO:0042023	regulation of DNA endoreduplication(GO:0032875) negative regulation of DNA endoreduplication(GO:0032876) DNA endoreduplication(GO:0042023)
0.0	0.0	GO:0042159	lipoprotein catabolic process(GO:0042159)
0.0	0.1	GO:0006884	cell volume homeostasis(GO:0006884)
0.0	0.0	GO:0051097	negative regulation of helicase activity(GO:0051097)
0.0	0.0	GO:0018126	protein hydroxylation(GO:0018126)
0.0	0.1	GO:0006621	protein retention in ER lumen(GO:0006621) maintenance of protein localization in endoplasmic reticulum(GO:0035437)
0.0	0.0	GO:0042532	negative regulation of tyrosine phosphorylation of STAT protein(GO:0042532)
0.0	0.1	GO:0051412	response to corticosterone(GO:0051412)
0.0	0.0	GO:0006419	alanyl-tRNA aminoacylation(GO:0006419)
0.0	0.0	GO:0032049	phosphatidylglycerol biosynthetic process(GO:0006655) cardiolipin metabolic process(GO:0032048) cardiolipin biosynthetic process(GO:0032049) phosphatidylglycerol metabolic process(GO:0046471)
0.0	0.0	GO:0006534	cysteine metabolic process(GO:0006534)
0.0	0.1	GO:0010257	NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.0	0.0	GO:0030263	apoptotic chromosome condensation(GO:0030263)
0.0	0.0	GO:0050774	negative regulation of dendrite morphogenesis(GO:0050774)
0.0	0.0	GO:0032682	negative regulation of chemokine production(GO:0032682) negative regulation of chemokine biosynthetic process(GO:0045079)
0.0	0.1	GO:0046718	viral entry into host cell(GO:0046718)
0.0	0.1	GO:0016264	gap junction assembly(GO:0016264)
0.0	0.2	GO:0007340	acrosome reaction(GO:0007340)
0.0	0.1	GO:0061099	negative regulation of protein tyrosine kinase activity(GO:0061099)
0.0	0.8	GO:0006986	response to unfolded protein(GO:0006986)
0.0	0.0	GO:0006434	seryl-tRNA aminoacylation(GO:0006434)
0.0	0.1	GO:0006591	ornithine metabolic process(GO:0006591)
0.0	0.2	GO:0006783	heme biosynthetic process(GO:0006783)
0.0	0.1	GO:0015732	prostaglandin transport(GO:0015732)
0.0	0.0	GO:0051024	positive regulation of immunoglobulin secretion(GO:0051024)
0.0	0.0	GO:0048630	skeletal muscle tissue growth(GO:0048630)
0.0	0.0	GO:0032543	mitochondrial translation(GO:0032543)
0.0	0.0	GO:0006563	L-serine metabolic process(GO:0006563)
0.0	0.0	GO:0042161	plasma lipoprotein particle oxidation(GO:0034441) regulation of lipoprotein oxidation(GO:0034442) negative regulation of lipoprotein oxidation(GO:0034443) regulation of plasma lipoprotein particle oxidation(GO:0034444) negative regulation of plasma lipoprotein particle oxidation(GO:0034445) lipoprotein modification(GO:0042160) lipoprotein oxidation(GO:0042161)
0.0	0.0	GO:0055015	ventricular cardiac muscle cell development(GO:0055015)
0.0	0.1	GO:0071157	negative regulation of cell cycle arrest(GO:0071157)
0.0	0.0	GO:0032071	regulation of endodeoxyribonuclease activity(GO:0032071)
0.0	0.2	GO:0046854	phosphatidylinositol phosphorylation(GO:0046854)
0.0	0.1	GO:0033133	regulation of glucokinase activity(GO:0033131) positive regulation of glucokinase activity(GO:0033133) regulation of hexokinase activity(GO:1903299) positive regulation of hexokinase activity(GO:1903301)
0.0	0.0	GO:0003228	atrial cardiac muscle tissue development(GO:0003228) atrial cardiac muscle tissue morphogenesis(GO:0055009)
0.0	0.0	GO:0019886	antigen processing and presentation of exogenous peptide antigen via MHC class II(GO:0019886)
0.0	0.1	GO:0048168	regulation of neuronal synaptic plasticity(GO:0048168)
0.0	0.0	GO:0006167	AMP biosynthetic process(GO:0006167)
0.0	0.0	GO:0034720	histone H3-K4 demethylation(GO:0034720)
0.0	0.1	GO:0045749	obsolete negative regulation of S phase of mitotic cell cycle(GO:0045749)
0.0	0.0	GO:0060766	negative regulation of androgen receptor signaling pathway(GO:0060766)
0.0	0.1	GO:0032024	positive regulation of insulin secretion(GO:0032024)
0.0	0.0	GO:0032816	positive regulation of natural killer cell activation(GO:0032816)
0.0	0.0	GO:0032148	activation of protein kinase B activity(GO:0032148)
0.0	0.0	GO:0000733	DNA strand renaturation(GO:0000733)
0.0	0.0	GO:0030878	thyroid gland development(GO:0030878)
0.0	0.0	GO:0006391	transcription initiation from mitochondrial promoter(GO:0006391)
0.0	0.0	GO:0006549	isoleucine metabolic process(GO:0006549)
0.0	0.0	GO:0046007	negative regulation of activated T cell proliferation(GO:0046007)
0.0	0.0	GO:0043248	proteasome assembly(GO:0043248)
0.0	0.1	GO:0018027	peptidyl-lysine dimethylation(GO:0018027)
0.0	0.0	GO:0060575	intestinal epithelial cell differentiation(GO:0060575)
0.0	0.1	GO:0060314	regulation of ryanodine-sensitive calcium-release channel activity(GO:0060314)
0.0	0.1	GO:0040036	regulation of fibroblast growth factor receptor signaling pathway(GO:0040036)
0.0	0.1	GO:0045005	DNA-dependent DNA replication maintenance of fidelity(GO:0045005)
0.0	0.1	GO:1903051	negative regulation of proteolysis involved in cellular protein catabolic process(GO:1903051)
0.0	0.0	GO:0060850	regulation of transcription involved in cell fate commitment(GO:0060850)
0.0	0.0	GO:0021516	dorsal spinal cord development(GO:0021516)
0.0	0.1	GO:0006103	2-oxoglutarate metabolic process(GO:0006103)
0.0	0.1	GO:0051205	protein insertion into membrane(GO:0051205)
0.0	0.2	GO:0036503	ER-associated ubiquitin-dependent protein catabolic process(GO:0030433) ERAD pathway(GO:0036503)
0.0	0.1	GO:0014059	dopamine secretion(GO:0014046) regulation of dopamine secretion(GO:0014059)
0.0	0.0	GO:0042693	muscle cell fate commitment(GO:0042693)
0.0	0.1	GO:0032369	negative regulation of lipid transport(GO:0032369)
0.0	0.0	GO:0002027	regulation of heart rate(GO:0002027)
0.0	0.0	GO:0034382	chylomicron remnant clearance(GO:0034382) triglyceride-rich lipoprotein particle clearance(GO:0071830)
0.0	0.0	GO:0032922	circadian regulation of gene expression(GO:0032922)
0.0	0.1	GO:0007090	obsolete regulation of S phase of mitotic cell cycle(GO:0007090)
0.0	0.1	GO:0005984	disaccharide metabolic process(GO:0005984)
0.0	0.1	GO:0048625	myoblast fate commitment(GO:0048625)
0.0	0.0	GO:0061101	neuroendocrine cell differentiation(GO:0061101)
0.0	0.0	GO:0050667	homocysteine metabolic process(GO:0050667)
0.0	0.0	GO:0016559	peroxisome fission(GO:0016559)
0.0	0.0	GO:0021542	dentate gyrus development(GO:0021542)
0.0	0.0	GO:0003230	cardiac atrium morphogenesis(GO:0003209) cardiac atrium development(GO:0003230)
0.0	0.5	GO:0051084	'de novo' posttranslational protein folding(GO:0051084)
0.0	0.0	GO:0044240	multicellular organism lipid catabolic process(GO:0044240)
0.0	0.0	GO:0071569	protein ufmylation(GO:0071569)
0.0	0.2	GO:0051149	positive regulation of muscle cell differentiation(GO:0051149)
0.0	0.1	GO:1903078	positive regulation of establishment of protein localization to plasma membrane(GO:0090004) positive regulation of protein localization to plasma membrane(GO:1903078) positive regulation of protein localization to cell periphery(GO:1904377)
0.0	0.1	GO:0018345	protein palmitoylation(GO:0018345)
0.0	0.1	GO:1902221	L-phenylalanine metabolic process(GO:0006558) L-phenylalanine catabolic process(GO:0006559) erythrose 4-phosphate/phosphoenolpyruvate family amino acid metabolic process(GO:1902221) erythrose 4-phosphate/phosphoenolpyruvate family amino acid catabolic process(GO:1902222)
0.0	0.1	GO:0070206	protein trimerization(GO:0070206)
0.0	0.4	GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:0000184)
0.0	0.1	GO:0046498	S-adenosylhomocysteine metabolic process(GO:0046498)
0.0	0.3	GO:0000289	nuclear-transcribed mRNA poly(A) tail shortening(GO:0000289)
0.0	0.2	GO:0006004	fucose metabolic process(GO:0006004)
0.0	0.0	GO:0006590	thyroid hormone generation(GO:0006590)
0.0	0.0	GO:0035058	nonmotile primary cilium assembly(GO:0035058)
0.0	0.2	GO:0002474	antigen processing and presentation of peptide antigen via MHC class I(GO:0002474)
0.0	0.1	GO:0006734	NADH metabolic process(GO:0006734)
0.0	0.0	GO:0071549	cellular response to dexamethasone stimulus(GO:0071549)
0.0	0.0	GO:0030262	apoptotic nuclear changes(GO:0030262)
0.0	0.0	GO:0061726	mitophagy(GO:0000422) mitochondrion disassembly(GO:0061726)
0.0	0.0	GO:0001953	negative regulation of cell-matrix adhesion(GO:0001953)
0.0	0.0	GO:0048319	axial mesoderm morphogenesis(GO:0048319)
0.0	0.0	GO:0051790	short-chain fatty acid biosynthetic process(GO:0051790)
0.0	0.0	GO:0055094	response to lipoprotein particle(GO:0055094)
0.0	0.3	GO:1902099	regulation of mitotic metaphase/anaphase transition(GO:0030071) regulation of metaphase/anaphase transition of cell cycle(GO:1902099)
0.0	0.0	GO:0042523	positive regulation of tyrosine phosphorylation of Stat5 protein(GO:0042523)
0.0	0.0	GO:0042866	pyruvate biosynthetic process(GO:0042866)
0.0	0.2	GO:0032436	positive regulation of proteasomal ubiquitin-dependent protein catabolic process(GO:0032436) positive regulation of proteasomal protein catabolic process(GO:1901800)
0.0	0.2	GO:0006308	DNA catabolic process(GO:0006308)
0.0	0.0	GO:0032410	negative regulation of transporter activity(GO:0032410)
0.0	0.0	GO:0071428	rRNA-containing ribonucleoprotein complex export from nucleus(GO:0071428)
0.0	0.0	GO:0060292	long term synaptic depression(GO:0060292)
0.0	0.1	GO:0032201	telomere maintenance via semi-conservative replication(GO:0032201)
0.0	0.0	GO:0009448	gamma-aminobutyric acid metabolic process(GO:0009448)
0.0	0.0	GO:0014743	regulation of cardiac muscle hypertrophy(GO:0010611) regulation of muscle hypertrophy(GO:0014743)
0.0	0.0	GO:0015853	adenine transport(GO:0015853)
0.0	0.1	GO:0043278	response to isoquinoline alkaloid(GO:0014072) response to morphine(GO:0043278)
0.0	0.1	GO:0045047	protein targeting to ER(GO:0045047) establishment of protein localization to endoplasmic reticulum(GO:0072599)
0.0	0.0	GO:0051708	intracellular transport of viral protein in host cell(GO:0019060) symbiont intracellular protein transport in host(GO:0030581) regulation by virus of viral protein levels in host cell(GO:0046719) intracellular protein transport in other organism involved in symbiotic interaction(GO:0051708)
0.0	0.0	GO:0031440	regulation of mRNA 3'-end processing(GO:0031440)
0.0	0.0	GO:0051299	centrosome separation(GO:0051299)
0.0	0.2	GO:0001522	pseudouridine synthesis(GO:0001522)
0.0	0.1	GO:0061462	protein targeting to lysosome(GO:0006622) protein targeting to vacuole(GO:0006623) protein localization to lysosome(GO:0061462) protein localization to vacuole(GO:0072665) establishment of protein localization to vacuole(GO:0072666)
0.0	0.0	GO:0035520	monoubiquitinated protein deubiquitination(GO:0035520)
0.0	0.7	GO:0042787	protein ubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0042787)
0.0	0.0	GO:0060009	Sertoli cell development(GO:0060009)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.4	GO:0030056	hemidesmosome(GO:0030056)
0.1	0.3	GO:0032449	CBM complex(GO:0032449)
0.1	0.8	GO:0016342	catenin complex(GO:0016342)
0.1	0.7	GO:0002102	podosome(GO:0002102)
0.1	0.3	GO:0032059	bleb(GO:0032059)
0.1	0.3	GO:0005915	zonula adherens(GO:0005915)
0.1	0.4	GO:0005593	FACIT collagen trimer(GO:0005593)
0.1	0.2	GO:0070022	transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.1	0.4	GO:0033256	I-kappaB/NF-kappaB complex(GO:0033256)
0.1	0.2	GO:0043259	laminin-10 complex(GO:0043259)
0.1	0.2	GO:0071001	U4/U6 snRNP(GO:0071001)
0.1	0.4	GO:0043256	laminin complex(GO:0043256)
0.1	0.1	GO:0014704	intercalated disc(GO:0014704) cell-cell contact zone(GO:0044291)
0.1	0.5	GO:0030122	AP-2 adaptor complex(GO:0030122) clathrin coat of endocytic vesicle(GO:0030128)
0.1	0.3	GO:0031362	anchored component of external side of plasma membrane(GO:0031362)
0.1	0.5	GO:0005890	sodium:potassium-exchanging ATPase complex(GO:0005890)
0.1	0.2	GO:0016327	apicolateral plasma membrane(GO:0016327)
0.1	0.2	GO:0031904	endosome lumen(GO:0031904)
0.1	0.4	GO:0098642	network-forming collagen trimer(GO:0098642) collagen network(GO:0098645)
0.1	0.2	GO:0034673	inhibin-betaglycan-ActRII complex(GO:0034673)
0.1	0.4	GO:0031143	pseudopodium(GO:0031143)
0.0	0.1	GO:0031941	filamentous actin(GO:0031941)
0.0	0.3	GO:0031232	extrinsic component of external side of plasma membrane(GO:0031232)
0.0	0.1	GO:0098647	collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.0	0.1	GO:0048179	activin receptor complex(GO:0048179)
0.0	0.2	GO:0036454	insulin-like growth factor binding protein complex(GO:0016942) growth factor complex(GO:0036454)
0.0	0.1	GO:0005945	6-phosphofructokinase complex(GO:0005945)
0.0	0.1	GO:0033185	mannosyltransferase complex(GO:0031501) dolichol-phosphate-mannose synthase complex(GO:0033185)
0.0	0.2	GO:0005638	lamin filament(GO:0005638)
0.0	0.2	GO:0005828	kinetochore microtubule(GO:0005828)
0.0	0.1	GO:0070852	cell body fiber(GO:0070852)
0.0	0.5	GO:0071564	npBAF complex(GO:0071564)
0.0	1.1	GO:0097517	stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.0	0.2	GO:0031512	motile primary cilium(GO:0031512)
0.0	0.0	GO:0005652	nuclear lamina(GO:0005652)
0.0	0.2	GO:0071204	histone pre-mRNA 3'end processing complex(GO:0071204)
0.0	0.1	GO:0031933	telomeric heterochromatin(GO:0031933)
0.0	0.1	GO:0009331	glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.0	0.2	GO:0031211	palmitoyltransferase complex(GO:0002178) serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211)
0.0	0.2	GO:0005853	eukaryotic translation elongation factor 1 complex(GO:0005853)
0.0	0.1	GO:0000124	SAGA complex(GO:0000124)
0.0	0.1	GO:0071818	BAT3 complex(GO:0071818) ER membrane insertion complex(GO:0072379)
0.0	0.2	GO:0032588	trans-Golgi network membrane(GO:0032588)
0.0	0.9	GO:0005637	nuclear inner membrane(GO:0005637)
0.0	0.2	GO:0090576	RNA polymerase III transcription factor complex(GO:0090576)
0.0	0.1	GO:0031371	ubiquitin conjugating enzyme complex(GO:0031371)
0.0	0.1	GO:0071062	alphav-beta3 integrin-vitronectin complex(GO:0071062)
0.0	0.1	GO:0031528	microvillus membrane(GO:0031528)
0.0	0.3	GO:0031463	Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0	0.0	GO:0034993	microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.0	0.1	GO:0043657	host(GO:0018995) host cell part(GO:0033643) host intracellular part(GO:0033646) intracellular region of host(GO:0043656) host cell(GO:0043657) other organism(GO:0044215) other organism cell(GO:0044216) other organism part(GO:0044217)
0.0	0.6	GO:0030057	desmosome(GO:0030057)
0.0	0.1	GO:0030688	preribosome, small subunit precursor(GO:0030688)
0.0	0.5	GO:0012507	ER to Golgi transport vesicle membrane(GO:0012507)
0.0	0.1	GO:0005863	striated muscle myosin thick filament(GO:0005863)
0.0	0.1	GO:0070188	obsolete Stn1-Ten1 complex(GO:0070188)
0.0	0.1	GO:0070044	synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044)
0.0	1.6	GO:0030426	growth cone(GO:0030426)
0.0	0.5	GO:0000159	protein phosphatase type 2A complex(GO:0000159)
0.0	0.3	GO:0005675	holo TFIIH complex(GO:0005675)
0.0	0.3	GO:0000109	nucleotide-excision repair complex(GO:0000109)
0.0	0.2	GO:0031430	M band(GO:0031430)
0.0	0.2	GO:0005614	interstitial matrix(GO:0005614)
0.0	0.1	GO:0001739	sex chromatin(GO:0001739)
0.0	0.1	GO:0071565	nBAF complex(GO:0071565)
0.0	0.1	GO:0032591	dendritic spine membrane(GO:0032591)
0.0	2.3	GO:0005925	focal adhesion(GO:0005925)
0.0	0.1	GO:0060205	cytoplasmic membrane-bounded vesicle lumen(GO:0060205)
0.0	0.1	GO:0002080	acrosomal membrane(GO:0002080)
0.0	0.2	GO:0034451	centriolar satellite(GO:0034451)
0.0	0.1	GO:0030121	AP-1 adaptor complex(GO:0030121)
0.0	0.2	GO:0008091	spectrin(GO:0008091)
0.0	0.1	GO:0005850	eukaryotic translation initiation factor 2 complex(GO:0005850)
0.0	1.0	GO:0031093	platelet alpha granule lumen(GO:0031093)
0.0	0.2	GO:0034464	BBSome(GO:0034464)
0.0	0.6	GO:0000932	cytoplasmic mRNA processing body(GO:0000932)
0.0	0.0	GO:0035253	ciliary rootlet(GO:0035253)
0.0	0.1	GO:0005605	basal lamina(GO:0005605)
0.0	0.2	GO:0005847	mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.0	0.1	GO:0016011	dystroglycan complex(GO:0016011) sarcoglycan complex(GO:0016012)
0.0	0.3	GO:0008328	ionotropic glutamate receptor complex(GO:0008328) neurotransmitter receptor complex(GO:0098878)
0.0	0.0	GO:0030427	site of polarized growth(GO:0030427)
0.0	0.1	GO:0000300	obsolete peripheral to membrane of membrane fraction(GO:0000300)
0.0	0.1	GO:1990316	ATG1/ULK1 kinase complex(GO:1990316)
0.0	0.1	GO:0043240	Fanconi anaemia nuclear complex(GO:0043240)
0.0	0.8	GO:0005912	adherens junction(GO:0005912)
0.0	0.1	GO:0005851	eukaryotic translation initiation factor 2B complex(GO:0005851)
0.0	0.0	GO:0032432	actin filament bundle(GO:0032432)
0.0	0.0	GO:0031618	nuclear pericentric heterochromatin(GO:0031618)
0.0	0.1	GO:0043034	costamere(GO:0043034)
0.0	0.4	GO:0005581	collagen trimer(GO:0005581)
0.0	0.1	GO:0005677	chromatin silencing complex(GO:0005677)
0.0	0.3	GO:0001673	male germ cell nucleus(GO:0001673)
0.0	5.0	GO:0005578	proteinaceous extracellular matrix(GO:0005578)
0.0	0.4	GO:0042612	MHC class I protein complex(GO:0042612)
0.0	0.1	GO:0043218	compact myelin(GO:0043218)
0.0	0.1	GO:0042587	glycogen granule(GO:0042587)
0.0	0.1	GO:0042824	MHC class I peptide loading complex(GO:0042824)
0.0	0.1	GO:0005832	chaperonin-containing T-complex(GO:0005832)
0.0	0.1	GO:0005678	obsolete chromatin assembly complex(GO:0005678)
0.0	0.0	GO:0014731	spectrin-associated cytoskeleton(GO:0014731)
0.0	0.1	GO:0014701	junctional sarcoplasmic reticulum membrane(GO:0014701)
0.0	0.3	GO:0016328	lateral plasma membrane(GO:0016328)
0.0	0.1	GO:0005751	mitochondrial respiratory chain complex IV(GO:0005751) respiratory chain complex IV(GO:0045277)
0.0	0.0	GO:0045298	tubulin complex(GO:0045298)
0.0	0.4	GO:0000307	cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.0	0.3	GO:0031594	neuromuscular junction(GO:0031594)
0.0	0.2	GO:0060170	ciliary membrane(GO:0060170)
0.0	0.1	GO:0005797	Golgi medial cisterna(GO:0005797)
0.0	0.1	GO:0000444	MIS12/MIND type complex(GO:0000444)
0.0	0.1	GO:0051233	spindle midzone(GO:0051233)
0.0	0.4	GO:0032587	ruffle membrane(GO:0032587)
0.0	0.0	GO:0042599	lamellar body(GO:0042599)
0.0	0.1	GO:0031312	extrinsic component of organelle membrane(GO:0031312)
0.0	1.6	GO:0045095	keratin filament(GO:0045095)
0.0	0.3	GO:0005922	connexon complex(GO:0005922)
0.0	0.0	GO:0042629	mast cell granule(GO:0042629)
0.0	0.1	GO:0016281	eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0	0.1	GO:0009925	basal plasma membrane(GO:0009925)
0.0	0.1	GO:0043190	ATP-binding cassette (ABC) transporter complex(GO:0043190)
0.0	0.1	GO:0061202	clathrin-sculpted gamma-aminobutyric acid transport vesicle(GO:0061200) clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane(GO:0061202)
0.0	0.1	GO:0031307	integral component of mitochondrial outer membrane(GO:0031307)
0.0	1.8	GO:0005911	cell-cell junction(GO:0005911)
0.0	0.2	GO:0005665	DNA-directed RNA polymerase II, core complex(GO:0005665)
0.0	0.2	GO:0005790	smooth endoplasmic reticulum(GO:0005790)
0.0	0.1	GO:0005658	alpha DNA polymerase:primase complex(GO:0005658)
0.0	0.7	GO:0016459	myosin complex(GO:0016459)
0.0	0.1	GO:0035145	exon-exon junction complex(GO:0035145)
0.0	0.1	GO:0001917	photoreceptor inner segment(GO:0001917)
0.0	0.1	GO:0000242	pericentriolar material(GO:0000242)
0.0	0.2	GO:0030864	cortical actin cytoskeleton(GO:0030864)
0.0	0.0	GO:0016602	CCAAT-binding factor complex(GO:0016602)
0.0	0.1	GO:0030877	beta-catenin destruction complex(GO:0030877)
0.0	1.0	GO:0030017	sarcomere(GO:0030017)
0.0	0.1	GO:0005663	DNA replication factor C complex(GO:0005663)
0.0	0.3	GO:0005871	kinesin complex(GO:0005871)
0.0	0.4	GO:0005680	anaphase-promoting complex(GO:0005680)
0.0	0.1	GO:0070822	Sin3 complex(GO:0016580) Sin3-type complex(GO:0070822)
0.0	0.1	GO:0010494	cytoplasmic stress granule(GO:0010494)
0.0	0.1	GO:0005655	nucleolar ribonuclease P complex(GO:0005655) ribonuclease P complex(GO:0030677) multimeric ribonuclease P complex(GO:0030681)
0.0	0.1	GO:0031265	CD95 death-inducing signaling complex(GO:0031265)
0.0	0.8	GO:0000922	spindle pole(GO:0000922)
0.0	0.1	GO:0001939	female pronucleus(GO:0001939)
0.0	0.1	GO:0008290	F-actin capping protein complex(GO:0008290)
0.0	0.2	GO:0046930	pore complex(GO:0046930)
0.0	0.2	GO:0005771	multivesicular body(GO:0005771)
0.0	0.0	GO:0033270	paranode region of axon(GO:0033270)
0.0	0.4	GO:0016592	mediator complex(GO:0016592)
0.0	0.0	GO:0030669	clathrin-coated endocytic vesicle membrane(GO:0030669)
0.0	0.1	GO:0005869	dynactin complex(GO:0005869)
0.0	0.2	GO:0005779	integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231)
0.0	0.1	GO:0016514	SWI/SNF complex(GO:0016514)
0.0	0.6	GO:0030176	integral component of endoplasmic reticulum membrane(GO:0030176)
0.0	0.0	GO:0045254	pyruvate dehydrogenase complex(GO:0045254)
0.0	0.2	GO:0005801	cis-Golgi network(GO:0005801)
0.0	0.2	GO:0005811	lipid particle(GO:0005811)
0.0	0.4	GO:0001726	ruffle(GO:0001726)
0.0	0.1	GO:0000275	mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275)
0.0	0.1	GO:0032838	cell projection cytoplasm(GO:0032838)
0.0	0.1	GO:0031305	integral component of mitochondrial inner membrane(GO:0031305)
0.0	0.4	GO:0001669	acrosomal vesicle(GO:0001669)
0.0	0.1	GO:0005833	hemoglobin complex(GO:0005833)
0.0	0.0	GO:0033018	sarcoplasmic reticulum lumen(GO:0033018)
0.0	0.4	GO:0000794	condensed nuclear chromosome(GO:0000794)
0.0	0.1	GO:0005697	telomerase holoenzyme complex(GO:0005697)
0.0	0.1	GO:0030315	T-tubule(GO:0030315)
0.0	0.1	GO:0035631	CD40 receptor complex(GO:0035631)
0.0	0.8	GO:0042470	melanosome(GO:0042470) pigment granule(GO:0048770)
0.0	1.3	GO:0016324	apical plasma membrane(GO:0016324)
0.0	0.1	GO:0005881	cytoplasmic microtubule(GO:0005881)
0.0	0.2	GO:0034364	high-density lipoprotein particle(GO:0034364)
0.0	1.1	GO:0031225	anchored component of membrane(GO:0031225)
0.0	0.1	GO:0031201	SNARE complex(GO:0031201)
0.0	0.1	GO:0005666	DNA-directed RNA polymerase III complex(GO:0005666)
0.0	0.1	GO:0048500	signal recognition particle, endoplasmic reticulum targeting(GO:0005786) signal recognition particle(GO:0048500)
0.0	0.0	GO:0030134	ER to Golgi transport vesicle(GO:0030134)
0.0	0.0	GO:0070937	CRD-mediated mRNA stability complex(GO:0070937)
0.0	0.0	GO:0042581	specific granule(GO:0042581)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	0.6	GO:0048018	receptor agonist activity(GO:0048018)
0.1	0.7	GO:0030618	transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity(GO:0030618)
0.1	0.4	GO:0005006	epidermal growth factor-activated receptor activity(GO:0005006)
0.1	0.6	GO:0048495	Roundabout binding(GO:0048495)
0.1	0.4	GO:0005025	transforming growth factor beta receptor activity, type I(GO:0005025)
0.1	0.4	GO:0015254	glycerol channel activity(GO:0015254)
0.1	0.3	GO:0051371	muscle alpha-actinin binding(GO:0051371)
0.1	0.3	GO:0005173	stem cell factor receptor binding(GO:0005173)
0.1	0.9	GO:0017166	vinculin binding(GO:0017166)
0.1	0.6	GO:0016290	palmitoyl-CoA hydrolase activity(GO:0016290)
0.1	0.4	GO:0030297	transmembrane receptor protein tyrosine kinase activator activity(GO:0030297)
0.1	0.7	GO:0003708	retinoic acid receptor activity(GO:0003708)
0.1	0.4	GO:0043237	laminin-1 binding(GO:0043237)
0.1	0.3	GO:0004995	tachykinin receptor activity(GO:0004995)
0.1	0.5	GO:0017154	semaphorin receptor activity(GO:0017154)
0.1	0.1	GO:0005017	platelet-derived growth factor-activated receptor activity(GO:0005017)
0.1	0.7	GO:0005112	Notch binding(GO:0005112)
0.1	0.2	GO:0050698	proteoglycan sulfotransferase activity(GO:0050698)
0.1	0.3	GO:0004157	dihydropyrimidinase activity(GO:0004157)
0.1	0.3	GO:0008401	retinoic acid 4-hydroxylase activity(GO:0008401)
0.1	0.1	GO:0030215	semaphorin receptor binding(GO:0030215)
0.1	0.3	GO:0043495	protein anchor(GO:0043495)
0.1	0.3	GO:0004032	alditol:NADP+ 1-oxidoreductase activity(GO:0004032)
0.1	0.2	GO:0004466	long-chain-acyl-CoA dehydrogenase activity(GO:0004466)
0.1	0.3	GO:0045499	chemorepellent activity(GO:0045499)
0.1	0.3	GO:0030235	nitric-oxide synthase regulator activity(GO:0030235)
0.1	0.2	GO:0033300	dehydroascorbic acid transporter activity(GO:0033300)
0.1	0.7	GO:0048407	platelet-derived growth factor binding(GO:0048407)
0.1	0.2	GO:0050508	glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0050508)
0.1	0.2	GO:0005148	prolactin receptor binding(GO:0005148)
0.1	0.2	GO:0016286	small conductance calcium-activated potassium channel activity(GO:0016286)
0.1	0.7	GO:0051010	microtubule plus-end binding(GO:0051010)
0.1	0.3	GO:0000828	inositol hexakisphosphate kinase activity(GO:0000828) inositol hexakisphosphate 5-kinase activity(GO:0000832)
0.1	0.2	GO:0055103	ligase regulator activity(GO:0055103) ubiquitin-protein transferase regulator activity(GO:0055106)
0.1	0.3	GO:0019211	phosphatase activator activity(GO:0019211)
0.1	0.4	GO:0050431	transforming growth factor beta binding(GO:0050431)
0.1	0.5	GO:0030332	cyclin binding(GO:0030332)
0.1	0.2	GO:0000900	translation repressor activity, nucleic acid binding(GO:0000900)
0.1	0.2	GO:0045159	myosin II binding(GO:0045159)
0.1	0.2	GO:0030371	translation repressor activity(GO:0030371)
0.1	0.3	GO:0042153	obsolete RPTP-like protein binding(GO:0042153)
0.1	0.2	GO:0050501	hyaluronan synthase activity(GO:0050501)
0.1	0.2	GO:0004849	uridine kinase activity(GO:0004849)
0.1	0.1	GO:0043533	inositol 1,3,4,5 tetrakisphosphate binding(GO:0043533)
0.1	0.2	GO:0016901	oxidoreductase activity, acting on the CH-OH group of donors, quinone or similar compound as acceptor(GO:0016901)
0.1	0.2	GO:0055077	gap junction hemi-channel activity(GO:0055077)
0.1	0.3	GO:0016717	oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water(GO:0016717)
0.1	0.4	GO:1900750	glutathione binding(GO:0043295) oligopeptide binding(GO:1900750)
0.0	0.1	GO:0034186	apolipoprotein A-I binding(GO:0034186)
0.0	0.2	GO:0070700	BMP receptor binding(GO:0070700)
0.0	0.3	GO:0004128	cytochrome-b5 reductase activity, acting on NAD(P)H(GO:0004128)
0.0	0.3	GO:0030506	ankyrin binding(GO:0030506)
0.0	0.1	GO:0004103	choline kinase activity(GO:0004103)
0.0	0.4	GO:0048185	activin binding(GO:0048185)
0.0	0.1	GO:0030911	TPR domain binding(GO:0030911)
0.0	0.3	GO:0004675	transmembrane receptor protein serine/threonine kinase activity(GO:0004675)
0.0	0.1	GO:0016212	kynurenine-oxoglutarate transaminase activity(GO:0016212) kynurenine aminotransferase activity(GO:0036137)
0.0	0.3	GO:0005237	inhibitory extracellular ligand-gated ion channel activity(GO:0005237)
0.0	0.1	GO:0016647	oxidoreductase activity, acting on the CH-NH group of donors, oxygen as acceptor(GO:0016647)
0.0	0.2	GO:0000293	ferric-chelate reductase activity(GO:0000293)
0.0	0.1	GO:0050682	AF-2 domain binding(GO:0050682)
0.0	0.1	GO:0005042	netrin receptor activity(GO:0005042)
0.0	0.4	GO:0047372	acylglycerol lipase activity(GO:0047372)
0.0	0.1	GO:0003872	6-phosphofructokinase activity(GO:0003872)
0.0	0.2	GO:0005010	insulin-like growth factor-activated receptor activity(GO:0005010)
0.0	0.3	GO:0003785	actin monomer binding(GO:0003785)
0.0	0.1	GO:0004582	dolichyl-phosphate beta-D-mannosyltransferase activity(GO:0004582)
0.0	0.1	GO:0016454	serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
0.0	0.2	GO:0015379	potassium:chloride symporter activity(GO:0015379)
0.0	0.1	GO:0050897	cobalt ion binding(GO:0050897)
0.0	0.0	GO:0001727	lipid kinase activity(GO:0001727)
0.0	0.1	GO:0042978	ornithine decarboxylase activator activity(GO:0042978)
0.0	0.3	GO:0044390	ubiquitin conjugating enzyme binding(GO:0031624) ubiquitin-like protein conjugating enzyme binding(GO:0044390)
0.0	0.1	GO:0060230	lipoprotein lipase activator activity(GO:0060230)
0.0	0.2	GO:0010314	phosphatidylinositol-5-phosphate binding(GO:0010314)
0.0	0.1	GO:0004999	vasoactive intestinal polypeptide receptor activity(GO:0004999)
0.0	0.1	GO:0019215	intermediate filament binding(GO:0019215)
0.0	0.2	GO:0005315	inorganic phosphate transmembrane transporter activity(GO:0005315)
0.0	0.2	GO:0031994	insulin-like growth factor I binding(GO:0031994)
0.0	0.2	GO:0008429	phosphatidylethanolamine binding(GO:0008429)
0.0	0.1	GO:0045545	syndecan binding(GO:0045545)
0.0	0.8	GO:0050699	WW domain binding(GO:0050699)
0.0	0.1	GO:0015018	galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity(GO:0015018)
0.0	0.1	GO:0032558	purine deoxyribonucleotide binding(GO:0032554) adenyl deoxyribonucleotide binding(GO:0032558)
0.0	0.1	GO:0005229	intracellular calcium activated chloride channel activity(GO:0005229)
0.0	0.1	GO:0032794	GTPase activating protein binding(GO:0032794)
0.0	0.1	GO:0003896	DNA primase activity(GO:0003896)
0.0	0.0	GO:0046848	hydroxyapatite binding(GO:0046848)
0.0	0.2	GO:0017176	phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.0	0.2	GO:0019238	cyclohydrolase activity(GO:0019238)
0.0	0.2	GO:0004470	malic enzyme activity(GO:0004470)
0.0	0.1	GO:0005384	manganese ion transmembrane transporter activity(GO:0005384)
0.0	0.3	GO:0046875	ephrin receptor binding(GO:0046875)
0.0	0.2	GO:0005110	frizzled-2 binding(GO:0005110)
0.0	0.4	GO:0005391	sodium:potassium-exchanging ATPase activity(GO:0005391)
0.0	0.4	GO:0051018	protein kinase A binding(GO:0051018)
0.0	0.1	GO:0051864	histone demethylase activity (H3-K36 specific)(GO:0051864)
0.0	0.3	GO:0043395	heparan sulfate proteoglycan binding(GO:0043395)
0.0	0.4	GO:0005109	frizzled binding(GO:0005109)
0.0	0.6	GO:0005546	phosphatidylinositol-4,5-bisphosphate binding(GO:0005546)
0.0	0.1	GO:0035514	DNA demethylase activity(GO:0035514) DNA-N1-methyladenine dioxygenase activity(GO:0043734)
0.0	0.1	GO:0004052	arachidonate 12-lipoxygenase activity(GO:0004052)
0.0	0.1	GO:0015168	glycerol transmembrane transporter activity(GO:0015168)
0.0	0.4	GO:0042301	phosphate ion binding(GO:0042301)
0.0	0.1	GO:0031545	procollagen-proline 4-dioxygenase activity(GO:0004656) peptidyl-proline 4-dioxygenase activity(GO:0031545)
0.0	0.4	GO:0008198	ferrous iron binding(GO:0008198)
0.0	0.2	GO:0043522	leucine zipper domain binding(GO:0043522)
0.0	0.1	GO:0008321	Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.0	0.2	GO:0070290	N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.0	0.1	GO:0008140	cAMP response element binding protein binding(GO:0008140)
0.0	0.0	GO:0005176	ErbB-2 class receptor binding(GO:0005176)
0.0	0.2	GO:0003706	obsolete ligand-regulated transcription factor activity(GO:0003706)
0.0	0.2	GO:0015288	porin activity(GO:0015288)
0.0	0.5	GO:0004198	calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0	0.1	GO:0004740	pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.0	0.2	GO:0050811	GABA receptor binding(GO:0050811)
0.0	0.1	GO:0031543	peptidyl-proline dioxygenase activity(GO:0031543)
0.0	0.1	GO:0030881	beta-2-microglobulin binding(GO:0030881)
0.0	0.1	GO:0034187	obsolete apolipoprotein E binding(GO:0034187)
0.0	0.1	GO:0008545	JUN kinase kinase activity(GO:0008545)
0.0	0.1	GO:0046980	tapasin binding(GO:0046980)
0.0	0.1	GO:0034711	inhibin binding(GO:0034711)
0.0	0.1	GO:0004814	arginine-tRNA ligase activity(GO:0004814)
0.0	0.1	GO:0031705	bombesin receptor binding(GO:0031705) endothelin B receptor binding(GO:0031708)
0.0	0.1	GO:0015272	ATP-activated inward rectifier potassium channel activity(GO:0015272)
0.0	0.1	GO:0004924	oncostatin-M receptor activity(GO:0004924)
0.0	0.1	GO:0043398	HLH domain binding(GO:0043398)
0.0	0.1	GO:0005105	type 1 fibroblast growth factor receptor binding(GO:0005105)
0.0	0.1	GO:0005078	MAP-kinase scaffold activity(GO:0005078)
0.0	0.1	GO:0008967	phosphoglycolate phosphatase activity(GO:0008967)
0.0	0.1	GO:0015187	glycine transmembrane transporter activity(GO:0015187)
0.0	0.1	GO:0005134	interleukin-2 receptor binding(GO:0005134)
0.0	0.1	GO:0004169	dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.0	0.1	GO:0032036	myosin heavy chain binding(GO:0032036)
0.0	0.1	GO:0030020	extracellular matrix structural constituent conferring tensile strength(GO:0030020)
0.0	0.2	GO:0050998	nitric-oxide synthase binding(GO:0050998)
0.0	0.1	GO:0031013	troponin I binding(GO:0031013)
0.0	0.3	GO:0035035	histone acetyltransferase binding(GO:0035035)
0.0	0.1	GO:0004516	nicotinate phosphoribosyltransferase activity(GO:0004516)
0.0	0.0	GO:0030284	estrogen receptor activity(GO:0030284)
0.0	0.1	GO:0008331	high voltage-gated calcium channel activity(GO:0008331)
0.0	0.5	GO:0050840	extracellular matrix binding(GO:0050840)
0.0	0.3	GO:0022829	wide pore channel activity(GO:0022829)
0.0	0.0	GO:0019855	calcium channel inhibitor activity(GO:0019855)
0.0	0.1	GO:0016595	glutamate binding(GO:0016595)
0.0	0.1	GO:0030151	molybdenum ion binding(GO:0030151)
0.0	0.1	GO:0004862	cAMP-dependent protein kinase inhibitor activity(GO:0004862)
0.0	0.2	GO:0015277	kainate selective glutamate receptor activity(GO:0015277)
0.0	0.3	GO:0070064	proline-rich region binding(GO:0070064)
0.0	0.0	GO:0000295	adenine nucleotide transmembrane transporter activity(GO:0000295) purine nucleotide transmembrane transporter activity(GO:0015216)
0.0	0.4	GO:0042809	vitamin D receptor binding(GO:0042809)
0.0	0.2	GO:0000014	single-stranded DNA endodeoxyribonuclease activity(GO:0000014)
0.0	0.1	GO:0050321	tau-protein kinase activity(GO:0050321)
0.0	0.1	GO:0008106	alcohol dehydrogenase (NADP+) activity(GO:0008106)
0.0	0.1	GO:0043184	vascular endothelial growth factor receptor 2 binding(GO:0043184)
0.0	0.2	GO:0004908	interleukin-1 receptor activity(GO:0004908)
0.0	0.3	GO:0016641	oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor(GO:0016641)
0.0	0.1	GO:0001515	opioid peptide activity(GO:0001515)
0.0	0.2	GO:0016713	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen(GO:0016713)
0.0	0.2	GO:0031369	translation initiation factor binding(GO:0031369)
0.0	0.1	GO:0047045	testosterone 17-beta-dehydrogenase (NADP+) activity(GO:0047045)
0.0	0.1	GO:0008294	calcium- and calmodulin-responsive adenylate cyclase activity(GO:0008294)
0.0	0.1	GO:0008432	JUN kinase binding(GO:0008432)
0.0	0.1	GO:0061133	endopeptidase activator activity(GO:0061133)
0.0	0.2	GO:0016833	oxo-acid-lyase activity(GO:0016833)
0.0	0.4	GO:0004653	polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.0	0.1	GO:0005007	fibroblast growth factor-activated receptor activity(GO:0005007)
0.0	0.3	GO:0004143	diacylglycerol kinase activity(GO:0004143)
0.0	0.1	GO:0004515	nicotinamide-nucleotide adenylyltransferase activity(GO:0000309) nicotinate-nucleotide adenylyltransferase activity(GO:0004515)
0.0	0.1	GO:0019958	C-X-C chemokine binding(GO:0019958) interleukin-8 binding(GO:0019959)
0.0	0.1	GO:0030172	troponin C binding(GO:0030172)
0.0	0.1	GO:0004523	RNA-DNA hybrid ribonuclease activity(GO:0004523)
0.0	0.1	GO:0097642	calcitonin family receptor activity(GO:0097642)
0.0	0.0	GO:0030507	spectrin binding(GO:0030507)
0.0	0.1	GO:0005047	signal recognition particle binding(GO:0005047)
0.0	0.0	GO:0015280	ligand-gated sodium channel activity(GO:0015280)
0.0	0.0	GO:0070095	fructose-6-phosphate binding(GO:0070095)
0.0	0.1	GO:0008502	melatonin receptor activity(GO:0008502)
0.0	0.1	GO:0004668	protein-arginine deiminase activity(GO:0004668)
0.0	0.3	GO:0030159	receptor signaling complex scaffold activity(GO:0030159)
0.0	0.0	GO:0001733	galactosylceramide sulfotransferase activity(GO:0001733) galactose 3-O-sulfotransferase activity(GO:0050694)
0.0	0.1	GO:0015057	thrombin receptor activity(GO:0015057)
0.0	1.0	GO:0004714	transmembrane receptor protein tyrosine kinase activity(GO:0004714) transmembrane receptor protein kinase activity(GO:0019199)
0.0	0.3	GO:0001619	obsolete lysosphingolipid and lysophosphatidic acid receptor activity(GO:0001619)
0.0	0.2	GO:0019894	kinesin binding(GO:0019894)
0.0	0.3	GO:0005104	fibroblast growth factor receptor binding(GO:0005104)
0.0	0.2	GO:0008469	histone-arginine N-methyltransferase activity(GO:0008469)
0.0	0.2	GO:0032947	protein complex scaffold(GO:0032947)
0.0	0.2	GO:0008641	small protein activating enzyme activity(GO:0008641)
0.0	0.0	GO:0005127	ciliary neurotrophic factor receptor binding(GO:0005127)
0.0	0.3	GO:0003711	obsolete transcription elongation regulator activity(GO:0003711)
0.0	0.1	GO:0050543	icosatetraenoic acid binding(GO:0050543)
0.0	0.1	GO:0034235	GPI anchor binding(GO:0034235)
0.0	0.1	GO:0046975	histone methyltransferase activity (H3-K36 specific)(GO:0046975)
0.0	0.1	GO:0005432	calcium:sodium antiporter activity(GO:0005432)
0.0	0.6	GO:0017137	Rab GTPase binding(GO:0017137)
0.0	0.4	GO:0005540	hyaluronic acid binding(GO:0005540)
0.0	0.4	GO:0051059	NF-kappaB binding(GO:0051059)
0.0	0.1	GO:0004645	phosphorylase activity(GO:0004645)
0.0	0.1	GO:0004803	transposase activity(GO:0004803)
0.0	0.2	GO:0004385	guanylate kinase activity(GO:0004385)
0.0	0.1	GO:0009374	biotin binding(GO:0009374)
0.0	0.1	GO:0004937	alpha1-adrenergic receptor activity(GO:0004937)
0.0	0.2	GO:0005337	nucleoside transmembrane transporter activity(GO:0005337)
0.0	0.1	GO:0004784	superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
0.0	0.2	GO:0016500	protein-hormone receptor activity(GO:0016500)
0.0	0.2	GO:0003709	obsolete RNA polymerase III transcription factor activity(GO:0003709)
0.0	0.1	GO:0031628	opioid receptor binding(GO:0031628)
0.0	0.1	GO:0045502	dynein binding(GO:0045502)
0.0	0.1	GO:0008526	phosphatidylinositol transporter activity(GO:0008526)
0.0	0.2	GO:0031419	cobalamin binding(GO:0031419)
0.0	0.1	GO:0004661	protein geranylgeranyltransferase activity(GO:0004661)
0.0	0.1	GO:0031996	thioesterase binding(GO:0031996)
0.0	0.1	GO:0031849	olfactory receptor binding(GO:0031849)
0.0	0.2	GO:0008066	glutamate receptor activity(GO:0008066)
0.0	0.1	GO:0047499	calcium-independent phospholipase A2 activity(GO:0047499)
0.0	0.0	GO:0002060	nucleobase binding(GO:0002054) purine nucleobase binding(GO:0002060)
0.0	0.2	GO:0051787	misfolded protein binding(GO:0051787)
0.0	0.1	GO:0048038	quinone binding(GO:0048038)
0.0	0.2	GO:0005234	extracellular-glutamate-gated ion channel activity(GO:0005234)
0.0	0.1	GO:0051879	Hsp90 protein binding(GO:0051879)
0.0	0.1	GO:0098847	single-stranded telomeric DNA binding(GO:0043047) sequence-specific single stranded DNA binding(GO:0098847)
0.0	0.1	GO:0015185	gamma-aminobutyric acid:sodium symporter activity(GO:0005332) gamma-aminobutyric acid transmembrane transporter activity(GO:0015185)
0.0	0.2	GO:0042605	peptide antigen binding(GO:0042605)
0.0	0.1	GO:0033765	steroid dehydrogenase activity, acting on the CH-CH group of donors(GO:0033765)
0.0	0.0	GO:0001671	ATPase activator activity(GO:0001671)
0.0	1.2	GO:0005201	extracellular matrix structural constituent(GO:0005201)
0.0	0.1	GO:0046965	retinoid X receptor binding(GO:0046965)
0.0	0.3	GO:0051117	ATPase binding(GO:0051117)
0.0	0.2	GO:0005159	insulin-like growth factor receptor binding(GO:0005159)
0.0	0.1	GO:0017060	3-galactosyl-N-acetylglucosaminide 4-alpha-L-fucosyltransferase activity(GO:0017060)
0.0	0.1	GO:0016832	aldehyde-lyase activity(GO:0016832)
0.0	0.1	GO:0070567	cytidylyltransferase activity(GO:0070567)
0.0	0.2	GO:0042162	telomeric DNA binding(GO:0042162)
0.0	0.1	GO:0003941	L-serine ammonia-lyase activity(GO:0003941)
0.0	0.1	GO:0003945	N-acetyllactosamine synthase activity(GO:0003945)
0.0	0.2	GO:0008143	poly(A) binding(GO:0008143)
0.0	0.1	GO:0070628	proteasome binding(GO:0070628)
0.0	0.2	GO:0005523	tropomyosin binding(GO:0005523)
0.0	0.1	GO:0004013	adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.0	0.1	GO:0008242	omega peptidase activity(GO:0008242)
0.0	0.1	GO:0051731	polynucleotide 5'-hydroxyl-kinase activity(GO:0051731)
0.0	0.1	GO:0015016	[heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
0.0	0.1	GO:0004594	pantothenate kinase activity(GO:0004594)
0.0	0.0	GO:0070548	L-glutamine aminotransferase activity(GO:0070548)
0.0	0.2	GO:0004707	MAP kinase activity(GO:0004707)
0.0	0.2	GO:0045296	cadherin binding(GO:0045296)
0.0	0.2	GO:0000155	phosphorelay sensor kinase activity(GO:0000155)
0.0	0.3	GO:0001540	beta-amyloid binding(GO:0001540)
0.0	0.1	GO:0008332	low voltage-gated calcium channel activity(GO:0008332)
0.0	0.1	GO:0070569	uridylyltransferase activity(GO:0070569)
0.0	0.1	GO:0051400	BH domain binding(GO:0051400)
0.0	0.1	GO:0055056	D-glucose transmembrane transporter activity(GO:0055056)
0.0	0.3	GO:0008601	protein phosphatase type 2A regulator activity(GO:0008601)
0.0	0.2	GO:0005452	inorganic anion exchanger activity(GO:0005452)
0.0	0.2	GO:0008353	RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.0	0.0	GO:0003923	GPI-anchor transamidase activity(GO:0003923)
0.0	0.0	GO:0030899	calcium-dependent ATPase activity(GO:0030899)
0.0	0.3	GO:0008093	cytoskeletal adaptor activity(GO:0008093)
0.0	0.1	GO:0070815	peptidyl-lysine 5-dioxygenase activity(GO:0070815)
0.0	0.0	GO:0008046	axon guidance receptor activity(GO:0008046)
0.0	0.1	GO:0016174	NAD(P)H oxidase activity(GO:0016174)
0.0	0.2	GO:0005123	death receptor binding(GO:0005123)
0.0	0.1	GO:0017110	nucleoside-diphosphatase activity(GO:0017110)
0.0	0.7	GO:0051015	actin filament binding(GO:0051015)
0.0	0.1	GO:0008266	poly(U) RNA binding(GO:0008266)
0.0	0.1	GO:0003854	3-beta-hydroxy-delta5-steroid dehydrogenase activity(GO:0003854)
0.0	0.0	GO:0003680	AT DNA binding(GO:0003680)
0.0	0.1	GO:0003689	DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.0	0.0	GO:0019834	phospholipase A2 inhibitor activity(GO:0019834)
0.0	0.2	GO:0008271	secondary active sulfate transmembrane transporter activity(GO:0008271)
0.0	0.2	GO:0001076	transcription factor activity, RNA polymerase II transcription factor binding(GO:0001076)
0.0	0.1	GO:0004033	aldo-keto reductase (NADP) activity(GO:0004033)
0.0	0.0	GO:0045294	alpha-catenin binding(GO:0045294)
0.0	0.1	GO:0047429	nucleoside-triphosphate diphosphatase activity(GO:0047429)
0.0	0.1	GO:0042800	histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.0	0.0	GO:0004828	serine-tRNA ligase activity(GO:0004828)
0.0	0.1	GO:0080030	methyl indole-3-acetate esterase activity(GO:0080030) methyl salicylate esterase activity(GO:0080031) methyl jasmonate esterase activity(GO:0080032)
0.0	0.5	GO:0001067	regulatory region DNA binding(GO:0000975) regulatory region nucleic acid binding(GO:0001067) transcription regulatory region DNA binding(GO:0044212)
0.0	0.0	GO:0004769	steroid delta-isomerase activity(GO:0004769)
0.0	0.2	GO:0001972	retinoic acid binding(GO:0001972)
0.0	0.0	GO:0016151	nickel cation binding(GO:0016151)
0.0	0.1	GO:0003906	DNA-(apurinic or apyrimidinic site) lyase activity(GO:0003906)
0.0	0.1	GO:0004111	creatine kinase activity(GO:0004111)
0.0	0.0	GO:0070513	death domain binding(GO:0070513)
0.0	0.0	GO:0034875	oxidoreductase activity, acting on CH or CH2 groups, quinone or similar compound as acceptor(GO:0033695) caffeine oxidase activity(GO:0034875)
0.0	0.0	GO:0034584	piRNA binding(GO:0034584)
0.0	0.0	GO:0003886	DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.0	0.1	GO:0030280	structural constituent of epidermis(GO:0030280)
0.0	0.0	GO:0030274	LIM domain binding(GO:0030274)
0.0	0.1	GO:0043531	ADP binding(GO:0043531)
0.0	0.2	GO:0005385	zinc ion transmembrane transporter activity(GO:0005385)
0.0	0.0	GO:0003960	NADPH:quinone reductase activity(GO:0003960)
0.0	0.0	GO:0043559	insulin binding(GO:0043559)
0.0	0.0	GO:0004060	arylamine N-acetyltransferase activity(GO:0004060)
0.0	0.1	GO:0000982	transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0000982) transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077) transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.0	0.2	GO:0032393	MHC class I receptor activity(GO:0032393)
0.0	0.0	GO:0004117	calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117)
0.0	0.1	GO:0036002	pre-mRNA binding(GO:0036002)
0.0	0.0	GO:0032453	histone demethylase activity (H3-K4 specific)(GO:0032453) histone demethylase activity (H3-dimethyl-K4 specific)(GO:0034648)
0.0	0.1	GO:0003986	acetyl-CoA hydrolase activity(GO:0003986)
0.0	0.1	GO:0004430	1-phosphatidylinositol 4-kinase activity(GO:0004430)
0.0	0.1	GO:0016861	intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861)
0.0	0.2	GO:0004065	arylsulfatase activity(GO:0004065)
0.0	0.0	GO:0008107	galactoside 2-alpha-L-fucosyltransferase activity(GO:0008107) alpha-(1,2)-fucosyltransferase activity(GO:0031127)
0.0	0.1	GO:0016805	dipeptidase activity(GO:0016805)
0.0	0.0	GO:0016941	natriuretic peptide receptor activity(GO:0016941)
0.0	0.1	GO:0031702	type 1 angiotensin receptor binding(GO:0031702)
0.0	0.1	GO:0005149	interleukin-1 receptor binding(GO:0005149)
0.0	0.1	GO:0009922	fatty acid elongase activity(GO:0009922)
0.0	0.0	GO:0000405	bubble DNA binding(GO:0000405)
0.0	0.1	GO:0017069	snRNA binding(GO:0017069)
0.0	0.1	GO:0015464	acetylcholine receptor activity(GO:0015464)
0.0	0.1	GO:0004427	inorganic diphosphatase activity(GO:0004427)
0.0	0.7	GO:0005200	structural constituent of cytoskeleton(GO:0005200)
0.0	0.0	GO:0061731	ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
0.0	0.1	GO:0008430	selenium binding(GO:0008430)
0.0	0.1	GO:0003956	NAD(P)+-protein-arginine ADP-ribosyltransferase activity(GO:0003956)
0.0	0.2	GO:0005484	SNAP receptor activity(GO:0005484)
0.0	0.2	GO:0004889	acetylcholine-activated cation-selective channel activity(GO:0004889)
0.0	0.1	GO:0019104	DNA N-glycosylase activity(GO:0019104)
0.0	0.1	GO:0005154	epidermal growth factor receptor binding(GO:0005154)
0.0	0.0	GO:0052834	inositol monophosphate 1-phosphatase activity(GO:0008934) inositol monophosphate phosphatase activity(GO:0052834)
0.0	0.0	GO:0016638	oxidoreductase activity, acting on the CH-NH2 group of donors(GO:0016638)
0.0	0.1	GO:0051920	peroxiredoxin activity(GO:0051920)
0.0	0.0	GO:0015183	L-aspartate transmembrane transporter activity(GO:0015183)
0.0	0.0	GO:0047184	1-acylglycerophosphocholine O-acyltransferase activity(GO:0047184)
0.0	0.2	GO:0030145	manganese ion binding(GO:0030145)
0.0	0.0	GO:0070996	type 1 melanocortin receptor binding(GO:0070996)
0.0	0.0	GO:0008296	3'-5'-exodeoxyribonuclease activity(GO:0008296)
0.0	1.6	GO:0003774	motor activity(GO:0003774)
0.0	1.3	GO:0004222	metalloendopeptidase activity(GO:0004222)
0.0	0.0	GO:0070576	vitamin D 24-hydroxylase activity(GO:0070576)
0.0	0.0	GO:0004607	phosphatidylcholine-sterol O-acyltransferase activity(GO:0004607)
0.0	0.2	GO:0003746	translation elongation factor activity(GO:0003746)
0.0	0.0	GO:0015065	uridine nucleotide receptor activity(GO:0015065) G-protein coupled pyrimidinergic nucleotide receptor activity(GO:0071553)
0.0	0.0	GO:0004938	alpha2-adrenergic receptor activity(GO:0004938)
0.0	0.1	GO:0005246	calcium channel regulator activity(GO:0005246)
0.0	0.8	GO:0005089	Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.0	0.0	GO:0000739	obsolete DNA strand annealing activity(GO:0000739)
0.0	0.0	GO:0043539	protein serine/threonine kinase activator activity(GO:0043539)
0.0	0.1	GO:0070568	guanylyltransferase activity(GO:0070568)
0.0	0.2	GO:0016645	oxidoreductase activity, acting on the CH-NH group of donors(GO:0016645)
0.0	0.6	GO:0031072	heat shock protein binding(GO:0031072)
0.0	2.2	GO:0004842	ubiquitin-protein transferase activity(GO:0004842)
0.0	0.1	GO:0004526	ribonuclease P activity(GO:0004526)
0.0	2.9	GO:0030528	obsolete transcription regulator activity(GO:0030528)
0.0	0.1	GO:0008239	dipeptidyl-peptidase activity(GO:0008239)
0.0	0.0	GO:0035242	protein-arginine omega-N asymmetric methyltransferase activity(GO:0035242)
0.0	0.2	GO:0008527	taste receptor activity(GO:0008527)
0.0	0.1	GO:0004185	serine-type carboxypeptidase activity(GO:0004185)
0.0	0.0	GO:0008384	IkappaB kinase activity(GO:0008384)
0.0	0.3	GO:0008173	RNA methyltransferase activity(GO:0008173)
0.0	0.2	GO:0004623	phospholipase A2 activity(GO:0004623)
0.0	0.0	GO:0010521	telomerase inhibitor activity(GO:0010521)
0.0	0.1	GO:0008171	O-methyltransferase activity(GO:0008171)
0.0	0.0	GO:0047961	glycine N-acyltransferase activity(GO:0047961)
0.0	0.1	GO:0004028	3-chloroallyl aldehyde dehydrogenase activity(GO:0004028)
0.0	0.1	GO:0017017	MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.1	PID EPHRINB REV PATHWAY	Ephrin B reverse signaling
0.1	1.0	PID ERBB NETWORK PATHWAY	ErbB receptor signaling network
0.1	0.1	NABA BASEMENT MEMBRANES	Genes encoding structural components of basement membranes
0.1	0.5	SA G2 AND M PHASES	Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.1	0.1	PID AVB3 OPN PATHWAY	Osteopontin-mediated events
0.1	0.7	PID INTEGRIN4 PATHWAY	Alpha6 beta4 integrin-ligand interactions
0.1	0.2	SA FAS SIGNALING	The TNF-type receptor Fas induces apoptosis on ligand binding.
0.1	0.1	PID CXCR3 PATHWAY	CXCR3-mediated signaling events
0.1	0.2	PID IGF1 PATHWAY	IGF1 pathway
0.1	1.3	PID RXR VDR PATHWAY	RXR and RAR heterodimerization with other nuclear receptor
0.0	0.7	PID ECADHERIN KERATINOCYTE PATHWAY	E-cadherin signaling in keratinocytes
0.0	0.9	PID A6B1 A6B4 INTEGRIN PATHWAY	a6b1 and a6b4 Integrin signaling
0.0	2.4	PID TGFBR PATHWAY	TGF-beta receptor signaling
0.0	0.1	PID MET PATHWAY	Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)
0.0	0.9	PID EPHA2 FWD PATHWAY	EPHA2 forward signaling
0.0	2.2	PID TAP63 PATHWAY	Validated transcriptional targets of TAp63 isoforms
0.0	0.1	PID PS1 PATHWAY	Presenilin action in Notch and Wnt signaling
0.0	0.4	PID INTEGRIN5 PATHWAY	Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.0	0.0	PID FAS PATHWAY	FAS (CD95) signaling pathway
0.0	0.8	PID NECTIN PATHWAY	Nectin adhesion pathway
0.0	0.3	PID VEGF VEGFR PATHWAY	VEGF and VEGFR signaling network
0.0	0.3	PID LYMPH ANGIOGENESIS PATHWAY	VEGFR3 signaling in lymphatic endothelium
0.0	0.2	PID RANBP2 PATHWAY	Sumoylation by RanBP2 regulates transcriptional repression
0.0	0.0	PID THROMBIN PAR4 PATHWAY	PAR4-mediated thrombin signaling events
0.0	1.1	PID ECADHERIN STABILIZATION PATHWAY	Stabilization and expansion of the E-cadherin adherens junction
0.0	0.2	PID S1P S1P1 PATHWAY	S1P1 pathway
0.0	0.8	PID RET PATHWAY	Signaling events regulated by Ret tyrosine kinase
0.0	0.1	PID PI3K PLC TRK PATHWAY	Trk receptor signaling mediated by PI3K and PLC-gamma
0.0	0.3	PID PDGFRA PATHWAY	PDGFR-alpha signaling pathway
0.0	1.4	NABA COLLAGENS	Genes encoding collagen proteins
0.0	0.6	PID CDC42 REG PATHWAY	Regulation of CDC42 activity
0.0	0.8	PID WNT SIGNALING PATHWAY	Wnt signaling network
0.0	0.2	PID TRKR PATHWAY	Neurotrophic factor-mediated Trk receptor signaling
0.0	0.3	PID S1P S1P4 PATHWAY	S1P4 pathway
0.0	0.2	SIG IL4RECEPTOR IN B LYPHOCYTES	Genes related to IL4 rceptor signaling in B lymphocytes
0.0	0.1	PID SYNDECAN 4 PATHWAY	Syndecan-4-mediated signaling events
0.0	0.9	PID INTEGRIN1 PATHWAY	Beta1 integrin cell surface interactions
0.0	0.2	SA TRKA RECEPTOR	The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth.
0.0	0.1	PID SYNDECAN 1 PATHWAY	Syndecan-1-mediated signaling events
0.0	0.4	PID HEDGEHOG 2PATHWAY	Signaling events mediated by the Hedgehog family
0.0	0.5	PID AURORA A PATHWAY	Aurora A signaling
0.0	0.3	PID BETA CATENIN DEG PATHWAY	Degradation of beta catenin
0.0	0.0	SA B CELL RECEPTOR COMPLEXES	Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.0	3.6	NABA ECM GLYCOPROTEINS	Genes encoding structural ECM glycoproteins
0.0	0.5	SIG CD40PATHWAYMAP	Genes related to CD40 signaling
0.0	0.2	PID NEPHRIN NEPH1 PATHWAY	Nephrin/Neph1 signaling in the kidney podocyte
0.0	0.5	ST WNT BETA CATENIN PATHWAY	Wnt/beta-catenin Pathway
0.0	0.4	PID LIS1 PATHWAY	Lissencephaly gene (LIS1) in neuronal migration and development
0.0	0.9	PID CDC42 PATHWAY	CDC42 signaling events
0.0	0.6	PID LKB1 PATHWAY	LKB1 signaling events
0.0	0.3	PID DELTA NP63 PATHWAY	Validated transcriptional targets of deltaNp63 isoforms
0.0	0.5	PID ILK PATHWAY	Integrin-linked kinase signaling
0.0	0.0	ST INTERLEUKIN 4 PATHWAY	Interleukin 4 (IL-4) Pathway
0.0	0.0	PID IL8 CXCR1 PATHWAY	IL8- and CXCR1-mediated signaling events
0.0	0.1	PID WNT NONCANONICAL PATHWAY	Noncanonical Wnt signaling pathway
0.0	0.1	PID SYNDECAN 3 PATHWAY	Syndecan-3-mediated signaling events
0.0	0.5	PID MTOR 4PATHWAY	mTOR signaling pathway
0.0	0.0	ST PHOSPHOINOSITIDE 3 KINASE PATHWAY	PI3K Pathway
0.0	0.3	PID AJDISS 2PATHWAY	Posttranslational regulation of adherens junction stability and dissassembly
0.0	0.0	PID IL23 PATHWAY	IL23-mediated signaling events
0.0	0.7	WNT SIGNALING	Genes related to Wnt-mediated signal transduction
0.0	0.0	PID VEGFR1 PATHWAY	VEGFR1 specific signals
0.0	0.0	PID REELIN PATHWAY	Reelin signaling pathway
0.0	0.0	PID ARF6 DOWNSTREAM PATHWAY	Arf6 downstream pathway
0.0	0.1	PID MAPK TRK PATHWAY	Trk receptor signaling mediated by the MAPK pathway
0.0	0.1	PID ALK2 PATHWAY	ALK2 signaling events
0.0	0.4	PID RHOA REG PATHWAY	Regulation of RhoA activity
0.0	0.4	NABA CORE MATRISOME	Ensemble of genes encoding core extracellular matrix including ECM glycoproteins, collagens and proteoglycans
0.0	0.3	PID P38 ALPHA BETA DOWNSTREAM PATHWAY	Signaling mediated by p38-alpha and p38-beta
0.0	0.1	SA PROGRAMMED CELL DEATH	Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.0	0.1	PID CERAMIDE PATHWAY	Ceramide signaling pathway
0.0	0.1	SA CASPASE CASCADE	Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.0	0.2	PID UPA UPAR PATHWAY	Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.0	0.4	PID AR PATHWAY	Coregulation of Androgen receptor activity
0.0	0.1	PID LPA4 PATHWAY	LPA4-mediated signaling events
0.0	0.3	PID HNF3A PATHWAY	FOXA1 transcription factor network

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	1.7	REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING	Genes involved in Downregulation of TGF-beta receptor signaling
0.1	1.1	REACTOME CRMPS IN SEMA3A SIGNALING	Genes involved in CRMPs in Sema3A signaling
0.1	0.8	REACTOME DCC MEDIATED ATTRACTIVE SIGNALING	Genes involved in DCC mediated attractive signaling
0.1	0.1	REACTOME CLASS A1 RHODOPSIN LIKE RECEPTORS	Genes involved in Class A/1 (Rhodopsin-like receptors)
0.1	0.9	REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS	Genes involved in Cell-extracellular matrix interactions
0.1	0.7	REACTOME ACTIVATION OF RAC	Genes involved in Activation of Rac
0.1	0.6	REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING	Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.0	0.0	REACTOME REGULATION OF GLUCOKINASE BY GLUCOKINASE REGULATORY PROTEIN	Genes involved in Regulation of Glucokinase by Glucokinase Regulatory Protein
0.0	0.2	REACTOME SEMA3A PAK DEPENDENT AXON REPULSION	Genes involved in Sema3A PAK dependent Axon repulsion
0.0	0.6	REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY	Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.0	0.1	REACTOME RNA POL III TRANSCRIPTION TERMINATION	Genes involved in RNA Polymerase III Transcription Termination
0.0	0.1	REACTOME G ALPHA1213 SIGNALLING EVENTS	Genes involved in G alpha (12/13) signalling events
0.0	0.5	REACTOME P130CAS LINKAGE TO MAPK SIGNALING FOR INTEGRINS	Genes involved in p130Cas linkage to MAPK signaling for integrins
0.0	0.4	REACTOME AKT PHOSPHORYLATES TARGETS IN THE CYTOSOL	Genes involved in AKT phosphorylates targets in the cytosol
0.0	0.6	REACTOME SIGNALING BY ROBO RECEPTOR	Genes involved in Signaling by Robo receptor
0.0	0.4	REACTOME SIGNALING BY FGFR3 MUTANTS	Genes involved in Signaling by FGFR3 mutants
0.0	0.6	REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS	Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0	0.1	REACTOME INHIBITION OF INSULIN SECRETION BY ADRENALINE NORADRENALINE	Genes involved in Inhibition of Insulin Secretion by Adrenaline/Noradrenaline
0.0	0.9	REACTOME SMOOTH MUSCLE CONTRACTION	Genes involved in Smooth Muscle Contraction
0.0	0.0	REACTOME DESTABILIZATION OF MRNA BY BRF1	Genes involved in Destabilization of mRNA by Butyrate Response Factor 1 (BRF1)
0.0	0.4	REACTOME MTORC1 MEDIATED SIGNALLING	Genes involved in mTORC1-mediated signalling
0.0	1.0	REACTOME LIPOPROTEIN METABOLISM	Genes involved in Lipoprotein metabolism
0.0	0.3	REACTOME TIE2 SIGNALING	Genes involved in Tie2 Signaling
0.0	0.1	REACTOME SHC MEDIATED SIGNALLING	Genes involved in SHC-mediated signalling
0.0	0.5	REACTOME ENOS ACTIVATION AND REGULATION	Genes involved in eNOS activation and regulation
0.0	0.1	REACTOME PD1 SIGNALING	Genes involved in PD-1 signaling
0.0	0.3	REACTOME NFKB IS ACTIVATED AND SIGNALS SURVIVAL	Genes involved in NF-kB is activated and signals survival
0.0	0.1	REACTOME INFLUENZA VIRAL RNA TRANSCRIPTION AND REPLICATION	Genes involved in Influenza Viral RNA Transcription and Replication
0.0	0.4	REACTOME PASSIVE TRANSPORT BY AQUAPORINS	Genes involved in Passive Transport by Aquaporins
0.0	0.5	REACTOME UNBLOCKING OF NMDA RECEPTOR GLUTAMATE BINDING AND ACTIVATION	Genes involved in Unblocking of NMDA receptor, glutamate binding and activation
0.0	0.4	REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE	Genes involved in Synthesis of PIPs at the early endosome membrane
0.0	0.9	REACTOME ADHERENS JUNCTIONS INTERACTIONS	Genes involved in Adherens junctions interactions
0.0	1.8	REACTOME COLLAGEN FORMATION	Genes involved in Collagen formation
0.0	0.1	REACTOME PECAM1 INTERACTIONS	Genes involved in PECAM1 interactions
0.0	0.2	REACTOME ROLE OF DCC IN REGULATING APOPTOSIS	Genes involved in Role of DCC in regulating apoptosis
0.0	0.4	REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS	Genes involved in Facilitative Na+-independent glucose transporters
0.0	0.7	REACTOME A TETRASACCHARIDE LINKER SEQUENCE IS REQUIRED FOR GAG SYNTHESIS	Genes involved in A tetrasaccharide linker sequence is required for GAG synthesis
0.0	0.3	REACTOME ACETYLCHOLINE NEUROTRANSMITTER RELEASE CYCLE	Genes involved in Acetylcholine Neurotransmitter Release Cycle
0.0	0.0	REACTOME NRAGE SIGNALS DEATH THROUGH JNK	Genes involved in NRAGE signals death through JNK
0.0	0.2	REACTOME DESTABILIZATION OF MRNA BY AUF1 HNRNP D0	Genes involved in Destabilization of mRNA by AUF1 (hnRNP D0)
0.0	0.0	REACTOME REGULATED PROTEOLYSIS OF P75NTR	Genes involved in Regulated proteolysis of p75NTR
0.0	0.4	REACTOME SIGNALING BY CONSTITUTIVELY ACTIVE EGFR	Genes involved in Signaling by constitutively active EGFR
0.0	0.2	REACTOME DSCAM INTERACTIONS	Genes involved in DSCAM interactions
0.0	0.1	REACTOME DOWNSTREAM SIGNALING EVENTS OF B CELL RECEPTOR BCR	Genes involved in Downstream Signaling Events Of B Cell Receptor (BCR)
0.0	0.6	REACTOME SIGNALING BY HIPPO	Genes involved in Signaling by Hippo
0.0	0.6	REACTOME BASIGIN INTERACTIONS	Genes involved in Basigin interactions
0.0	0.1	REACTOME CDK MEDIATED PHOSPHORYLATION AND REMOVAL OF CDC6	Genes involved in CDK-mediated phosphorylation and removal of Cdc6
0.0	0.2	REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS	Genes involved in Ionotropic activity of Kainate Receptors
0.0	0.1	REACTOME REGULATION OF WATER BALANCE BY RENAL AQUAPORINS	Genes involved in Regulation of Water Balance by Renal Aquaporins
0.0	0.3	REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA	Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.0	0.3	REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS	Genes involved in Synthesis of substrates in N-glycan biosythesis
0.0	0.6	REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 2 PROMOTER	Genes involved in RNA Polymerase III Transcription Initiation From Type 2 Promoter
0.0	0.1	REACTOME P75NTR SIGNALS VIA NFKB	Genes involved in p75NTR signals via NF-kB
0.0	0.5	REACTOME FORMATION OF INCISION COMPLEX IN GG NER	Genes involved in Formation of incision complex in GG-NER
0.0	0.3	REACTOME SIGNALING BY NOTCH3	Genes involved in Signaling by NOTCH3
0.0	0.6	REACTOME NUCLEAR SIGNALING BY ERBB4	Genes involved in Nuclear signaling by ERBB4
0.0	0.4	REACTOME NETRIN1 SIGNALING	Genes involved in Netrin-1 signaling
0.0	0.5	REACTOME SULFUR AMINO ACID METABOLISM	Genes involved in Sulfur amino acid metabolism
0.0	0.0	REACTOME ADP SIGNALLING THROUGH P2RY1	Genes involved in ADP signalling through P2Y purinoceptor 1
0.0	0.3	REACTOME ADENYLATE CYCLASE INHIBITORY PATHWAY	Genes involved in Adenylate cyclase inhibitory pathway
0.0	0.1	REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS	Genes involved in Membrane binding and targetting of GAG proteins
0.0	0.0	REACTOME FGFR4 LIGAND BINDING AND ACTIVATION	Genes involved in FGFR4 ligand binding and activation
0.0	0.4	REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS	Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.0	0.4	REACTOME FORMATION OF TUBULIN FOLDING INTERMEDIATES BY CCT TRIC	Genes involved in Formation of tubulin folding intermediates by CCT/TriC
0.0	0.0	REACTOME RNA POL I TRANSCRIPTION	Genes involved in RNA Polymerase I Transcription
0.0	0.4	REACTOME EFFECTS OF PIP2 HYDROLYSIS	Genes involved in Effects of PIP2 hydrolysis
0.0	0.9	REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY	Genes involved in Nuclear Receptor transcription pathway
0.0	0.1	REACTOME G ALPHA Z SIGNALLING EVENTS	Genes involved in G alpha (z) signalling events
0.0	0.3	REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS	Genes involved in Proteolytic cleavage of SNARE complex proteins
0.0	0.2	REACTOME GABA A RECEPTOR ACTIVATION	Genes involved in GABA A receptor activation
0.0	0.4	REACTOME NCAM1 INTERACTIONS	Genes involved in NCAM1 interactions
0.0	0.1	REACTOME INHIBITION OF REPLICATION INITIATION OF DAMAGED DNA BY RB1 E2F1	Genes involved in Inhibition of replication initiation of damaged DNA by RB1/E2F1
0.0	0.4	REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE	Genes involved in Amino acid transport across the plasma membrane
0.0	0.3	REACTOME SIGNALING BY BMP	Genes involved in Signaling by BMP
0.0	0.2	REACTOME BASE FREE SUGAR PHOSPHATE REMOVAL VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY	Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway
0.0	0.1	REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION	Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.0	0.2	REACTOME PROCESSIVE SYNTHESIS ON THE LAGGING STRAND	Genes involved in Processive synthesis on the lagging strand
0.0	0.2	REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES	Genes involved in Recruitment of NuMA to mitotic centrosomes
0.0	0.3	REACTOME HS GAG BIOSYNTHESIS	Genes involved in HS-GAG biosynthesis
0.0	0.6	REACTOME CELL JUNCTION ORGANIZATION	Genes involved in Cell junction organization
0.0	0.2	REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS	Genes involved in ABCA transporters in lipid homeostasis
0.0	0.3	REACTOME GAP JUNCTION ASSEMBLY	Genes involved in Gap junction assembly
0.0	0.1	REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING	Genes involved in Advanced glycosylation endproduct receptor signaling
0.0	0.2	REACTOME NONSENSE MEDIATED DECAY ENHANCED BY THE EXON JUNCTION COMPLEX	Genes involved in Nonsense Mediated Decay Enhanced by the Exon Junction Complex
0.0	1.3	REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS	Genes involved in Class B/2 (Secretin family receptors)
0.0	0.2	REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS	Genes involved in Regulation of gene expression in beta cells
0.0	0.0	REACTOME REGULATION OF APOPTOSIS	Genes involved in Regulation of Apoptosis
0.0	0.0	REACTOME GASTRIN CREB SIGNALLING PATHWAY VIA PKC AND MAPK	Genes involved in Gastrin-CREB signalling pathway via PKC and MAPK
0.0	0.1	REACTOME G2 M DNA DAMAGE CHECKPOINT	Genes involved in G2/M DNA damage checkpoint
0.0	0.2	REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE	Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.0	0.2	REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION	Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.0	0.2	REACTOME HYALURONAN METABOLISM	Genes involved in Hyaluronan metabolism
0.0	0.1	REACTOME METABOLISM OF POLYAMINES	Genes involved in Metabolism of polyamines
0.0	0.3	REACTOME INTERACTION BETWEEN L1 AND ANKYRINS	Genes involved in Interaction between L1 and Ankyrins
0.0	0.1	REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION	Genes involved in GABA synthesis, release, reuptake and degradation
0.0	0.0	REACTOME PROCESSING OF CAPPED INTRON CONTAINING PRE MRNA	Genes involved in Processing of Capped Intron-Containing Pre-mRNA
0.0	0.0	REACTOME FGFR2C LIGAND BINDING AND ACTIVATION	Genes involved in FGFR2c ligand binding and activation
0.0	0.2	REACTOME METABOLISM OF PORPHYRINS	Genes involved in Metabolism of porphyrins
0.0	0.1	REACTOME REGULATION OF INSULIN SECRETION BY GLUCAGON LIKE PEPTIDE1	Genes involved in Regulation of Insulin Secretion by Glucagon-like Peptide-1
0.0	0.1	REACTOME RNA POL I TRANSCRIPTION TERMINATION	Genes involved in RNA Polymerase I Transcription Termination
0.0	0.2	REACTOME ACETYLCHOLINE BINDING AND DOWNSTREAM EVENTS	Genes involved in Acetylcholine Binding And Downstream Events
0.0	0.3	REACTOME ACYL CHAIN REMODELLING OF PC	Genes involved in Acyl chain remodelling of PC
0.0	0.2	REACTOME FATTY ACYL COA BIOSYNTHESIS	Genes involved in Fatty Acyl-CoA Biosynthesis
0.0	0.2	REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS	Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.0	0.2	REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION	Genes involved in Amino acid synthesis and interconversion (transamination)
0.0	0.1	REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS	Genes involved in Extrinsic Pathway for Apoptosis
0.0	0.0	REACTOME APC C CDC20 MEDIATED DEGRADATION OF MITOTIC PROTEINS	Genes involved in APC/C:Cdc20 mediated degradation of mitotic proteins
0.0	0.2	REACTOME GLUCURONIDATION	Genes involved in Glucuronidation
0.0	0.1	REACTOME RIP MEDIATED NFKB ACTIVATION VIA DAI	Genes involved in RIP-mediated NFkB activation via DAI
0.0	0.2	REACTOME INHIBITION OF THE PROTEOLYTIC ACTIVITY OF APC C REQUIRED FOR THE ONSET OF ANAPHASE BY MITOTIC SPINDLE CHECKPOINT COMPONENTS	Genes involved in Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components
0.0	0.1	REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS	Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.0	0.1	REACTOME ACTIVATION OF BH3 ONLY PROTEINS	Genes involved in Activation of BH3-only proteins
0.0	0.0	REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE	Genes involved in Synthesis of PIPs at the late endosome membrane
0.0	0.0	REACTOME VIRAL MESSENGER RNA SYNTHESIS	Genes involved in Viral Messenger RNA Synthesis
0.0	0.2	REACTOME ENDOGENOUS STEROLS	Genes involved in Endogenous sterols
0.0	0.0	REACTOME CREB PHOSPHORYLATION THROUGH THE ACTIVATION OF CAMKII	Genes involved in CREB phosphorylation through the activation of CaMKII
0.0	0.1	REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX	Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.0	0.1	REACTOME SEROTONIN RECEPTORS	Genes involved in Serotonin receptors
0.0	1.7	REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION	Genes involved in Antigen processing: Ubiquitination & Proteasome degradation

Results for SMAD4

Z-value: 1.46

Motif logo

Transcription factors associated with SMAD4

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

Activity of the SMAD4 motif across conditions

Conditions sorted by the z-value of the SMAD4 motif activity

Top target CREs of the motif:

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of SMAD4

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category:

Gene overrepresentation in curated gene sets: canonical pathways category:

Gene overrepresentation in curated gene sets: REACTOME pathways category: