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ENCODE: H3K4me1 ChIP-Seq of primary human cells
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Results for SOX10_SOX15

Z-value: 0.89

Motif logo

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Transcription factors associated with SOX10_SOX15

Gene Symbol Gene ID Gene Info
SOX10
ENSG00000100146.12 SRY-box transcription factor 10
SOX15
ENSG00000129194.3 SRY-box transcription factor 15

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE Gene Distance Association probability Pearson corr. coef. P-value Plot
chr22_38378877_38379028SOX104690.6646190.646.5e-02Click!
chr22_38378547_38378698SOX107990.4438690.294.5e-01Click!
chr22_38383217_38383368SOX101370.880458-0.098.2e-01Click!
chr22_38382918_38383069SOX104360.5571460.078.5e-01Click!
chr17_7494297_7494448SOX158840.2447110.571.1e-01Click!
chr17_7493992_7494161SOX155880.3931600.551.2e-01Click!
chr17_7491559_7492035SOX1515930.1170790.531.4e-01Click!
chr17_7491173_7491417SOX1520950.0879310.501.7e-01Click!
chr17_7492402_7492756SOX158110.2696000.353.6e-01Click!

Activity of the SOX10_SOX15 motif across conditions

Conditions sorted by the z-value of the SOX10_SOX15 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE) Target Score Top associated gene Gene Info Distance of CRE to TSS CRE/Gene association probability
chr17_76370784_76371498 0.27 PGS1
 phosphatidylglycerophosphate synthase 1
 3580
 0.16
chr15_40081991_40082468 0.27 FSIP1
 fibrous sheath interacting protein 1
 7198
 0.17
chr14_72014650_72014936 0.23 SIPA1L1
 signal-induced proliferation-associated 1 like 1
 18751
 0.27
chr2_118981232_118982329 0.20 INSIG2
 insulin induced gene 2
 135730
 0.05
chr12_14412980_14413356 0.20 ENSG00000251908
 .
 9893
 0.22
chr9_33126556_33126826 0.20 B4GALT1
 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1
 1506
 0.36
chr3_171712617_171713197 0.19 FNDC3B
 fibronectin type III domain containing 3B
 44511
 0.17
chr11_10680453_10681322 0.19 MRVI1
 murine retrovirus integration site 1 homolog
 6964
 0.2
chr21_30557129_30557311 0.19 AF124730.4
2896
 0.17
chr20_17631217_17631686 0.19 RRBP1
 ribosome binding protein 1
 9701
 0.21
chr12_92683552_92683850 0.19 ENSG00000199895
 .
 119472
 0.05
chr5_17223674_17224319 0.19 BASP1
 brain abundant, membrane attached signal protein 1
 6327
 0.19
chr2_100630949_100631235 0.19 AFF3
 AF4/FMR2 family, member 3
 89900
 0.09
chr16_72405306_72405606 0.19 ENSG00000207514
 .
 5147
 0.31
chr7_80263577_80263846 0.18 CD36
 CD36 molecule (thrombospondin receptor)
 4249
 0.35
chr10_22605642_22606566 0.18 COMMD3
 COMM domain containing 3
 730
 0.4
chr20_9389511_9389662 0.18 PLCB4
 phospholipase C, beta 4
 101139
 0.07
chr6_127522710_127522861 0.18 RNF146
 ring finger protein 146
 64970
 0.12
chr1_178102702_178103151 0.18 RASAL2
 RAS protein activator like 2
 39650
 0.22
chr1_199660662_199660904 0.17 ENSG00000263805
 .
 76375
 0.12
chr7_102531454_102531734 0.17 LRRC17
 leucine rich repeat containing 17
 21844
 0.16
chr2_192135580_192135731 0.17 MYO1B
 myosin IB
 5956
 0.29
chr8_13081961_13082497 0.17 DLC1
 deleted in liver cancer 1
 51826
 0.15
chr4_14171315_14171588 0.17 ENSG00000252092
 .
 511200
 0.0
chr1_68112079_68112321 0.17 ENSG00000242482
 .
 10612
 0.23
chr8_99224065_99224216 0.17 ENSG00000252558
 .
 19599
 0.2
chr20_10286775_10287859 0.17 ENSG00000211588
 .
 55561
 0.13
chr4_71997510_71997784 0.17 SLC4A4
 solute carrier family 4 (sodium bicarbonate cotransporter), member 4
 55356
 0.16
chr11_95995991_95996601 0.17 ENSG00000266192
 .
 78306
 0.1
chr7_74603766_74604170 0.16 GTF2IRD2B
 GTF2I repeat domain containing 2B
 47064
 0.15
chr3_30537171_30537700 0.16 TGFBR2
 transforming growth factor, beta receptor II (70/80kDa)
 110559
 0.07
chr3_42104128_42104299 0.16 TRAK1
 trafficking protein, kinesin binding 1
 28349
 0.22
chr10_104913387_104913649 0.16 NT5C2
 5'-nucleotidase, cytosolic II
 134
 0.97
chr3_138581340_138581807 0.16 PIK3CB
 phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta
 27793
 0.2
chr15_77707876_77708432 0.16 PEAK1
 pseudopodium-enriched atypical kinase 1
 4288
 0.26
chr14_73881929_73882217 0.16 NUMB
 numb homolog (Drosophila)
 5294
 0.21
chr14_68608308_68608459 0.16 ENSG00000244677
 .
 8242
 0.23
chr11_9774706_9775022 0.16 SBF2-AS1
 SBF2 antisense RNA 1
 4975
 0.2
chr17_70973648_70973899 0.16 SLC39A11
 solute carrier family 39, member 11
 15299
 0.27
chr3_17794774_17794953 0.16 TBC1D5
 TBC1 domain family, member 5
 10719
 0.3
chr15_51602118_51602364 0.16 CYP19A1
 cytochrome P450, family 19, subfamily A, polypeptide 1
 8448
 0.17
chr3_123668814_123668965 0.15 CCDC14
 coiled-coil domain containing 14
 467
 0.84
chr4_141158577_141158955 0.15 SCOC
 short coiled-coil protein
 19674
 0.2
chr1_9952782_9953028 0.15 CTNNBIP1
 catenin, beta interacting protein 1
 390
 0.81
chr5_111304224_111304663 0.15 NREP-AS1
 NREP antisense RNA 1
 706
 0.74
chr4_12124809_12125078 0.15 ENSG00000266669
 .
 109878
 0.08
chr6_144355824_144356097 0.15 PLAGL1
 pleiomorphic adenoma gene-like 1
 26419
 0.21
chr1_155732961_155733524 0.15 DAP3
 death associated protein 3
 26439
 0.13
chr12_25920871_25921133 0.15 ENSG00000222950
 .
 11501
 0.28
chr10_99115891_99116310 0.15 FRAT2
 frequently rearranged in advanced T-cell lymphomas 2
 21642
 0.1
chr3_43807500_43807651 0.15 ABHD5
 abhydrolase domain containing 5
 54376
 0.15
chr5_52109798_52109949 0.15 CTD-2288O8.1
26013
 0.17
chr3_159886438_159886589 0.15 IL12A-AS1
 IL12A antisense RNA 1
 38366
 0.15
chr2_74810778_74811272 0.15 LOXL3
 lysyl oxidase-like 3
 28208
 0.08
chr2_131095295_131095532 0.15 IMP4
 IMP4, U3 small nucleolar ribonucleoprotein, homolog (yeast)
 4385
 0.17
chr5_114919475_114919626 0.15 AC010226.4
18204
 0.15
chr1_155618391_155618704 0.15 YY1AP1
 YY1 associated protein 1
 27915
 0.11
chr9_94048455_94048658 0.14 AUH
 AU RNA binding protein/enoyl-CoA hydratase
 75621
 0.12
chr2_192251959_192252110 0.14 MYO1B
 myosin IB
 4826
 0.27
chr7_36205351_36205624 0.14 EEPD1
 endonuclease/exonuclease/phosphatase family domain containing 1
 12610
 0.22
chr1_10182603_10182825 0.14 UBE4B
 ubiquitination factor E4B
 614
 0.74
chr12_109057635_109057786 0.14 ENSG00000238457
 .
 4514
 0.16
chr22_39688804_39689038 0.14 RP3-333H23.8
72
 0.95
chr3_148917359_148917687 0.14 CP
 ceruloplasmin (ferroxidase)
 9604
 0.22
chr6_16681395_16681795 0.14 RP1-151F17.1
79774
 0.1
chr2_20644033_20644184 0.14 RHOB
 ras homolog family member B
 2727
 0.28
chr17_13268235_13268519 0.14 ENSG00000266115
 .
 135268
 0.05
chr12_66590752_66591050 0.14 IRAK3
 interleukin-1 receptor-associated kinase 3
 7864
 0.16
chr5_136900207_136900561 0.14 ENSG00000221612
 .
 31241
 0.19
chr1_203517854_203518108 0.14 OPTC
 opticin
 52883
 0.13
chr8_59506824_59506976 0.14 SDCBP
 syndecan binding protein (syntenin)
 29325
 0.19
chr12_32655690_32655927 0.14 FGD4
 FYVE, RhoGEF and PH domain containing 4
 657
 0.77
chr3_171549465_171549722 0.14 TMEM212
 transmembrane protein 212
 11546
 0.18
chr1_214568255_214568406 0.14 RP11-176D17.3
37372
 0.19
chr6_56778927_56779078 0.14 ENSG00000200224
 .
 31526
 0.16
chr17_60953332_60953660 0.14 MARCH10
 membrane-associated ring finger (C3HC4) 10, E3 ubiquitin protein ligase
 67791
 0.11
chr6_114290051_114291212 0.14 RP3-399L15.3
234
 0.87
chr7_92242355_92242506 0.14 FAM133B
 family with sequence similarity 133, member B
 22722
 0.2
chr3_179134884_179135173 0.14 GNB4
 guanine nucleotide binding protein (G protein), beta polypeptide 4
 714
 0.64
chr9_33321157_33321399 0.14 NFX1
 nuclear transcription factor, X-box binding 1
 30735
 0.12
chr10_77229212_77229699 0.14 RP11-399K21.10
38109
 0.16
chr16_50286306_50286457 0.14 ADCY7
 adenylate cyclase 7
 6333
 0.22
chr11_61738752_61739315 0.14 AP003733.1
 Uncharacterized protein; cDNA FLJ36460 fis, clone THYMU2014801
 3580
 0.16
chr3_138841521_138841672 0.13 MRPS22
 mitochondrial ribosomal protein S22
 12350
 0.24
chr7_98737042_98737396 0.13 SMURF1
 SMAD specific E3 ubiquitin protein ligase 1
 4423
 0.27
chr6_129988972_129989261 0.13 ARHGAP18
 Rho GTPase activating protein 18
 42254
 0.19
chr2_161887841_161887992 0.13 TANK
 TRAF family member-associated NFKB activator
 105503
 0.07
chr4_118055843_118055994 0.13 TRAM1L1
 translocation associated membrane protein 1-like 1
 49182
 0.2
chr1_110364191_110364827 0.13 EPS8L3
 EPS8-like 3
 57860
 0.08
chr4_7925984_7926135 0.13 AC097381.1
14669
 0.19
chr21_27307663_27307857 0.13 ENSG00000233783
 .
 1134
 0.52
chr1_98552609_98552760 0.13 ENSG00000225206
 .
 40957
 0.22
chr10_79002677_79003016 0.13 RP11-328K22.1
70853
 0.11
chr4_74600301_74600499 0.13 IL8
 interleukin 8
 5823
 0.26
chr6_106247000_106247228 0.13 ENSG00000200198
 .
 105134
 0.08
chr1_221099074_221099301 0.13 HLX
 H2.0-like homeobox
 44603
 0.15
chr3_135570414_135570565 0.13 ENSG00000253004
 .
 51867
 0.17
chr22_24869928_24870164 0.13 UPB1
 ureidopropionase, beta
 6840
 0.16
chr10_65281872_65282748 0.13 REEP3
 receptor accessory protein 3
 1187
 0.58
chr10_13981760_13981911 0.13 FRMD4A
 FERM domain containing 4A
 32534
 0.19
chr2_11837137_11837372 0.13 AC106875.1
15667
 0.12
chr6_107644259_107644527 0.13 PDSS2
 prenyl (decaprenyl) diphosphate synthase, subunit 2
 111030
 0.06
chr2_208101022_208101173 0.13 AC007879.5
17879
 0.2
chr12_79814559_79814710 0.13 ENSG00000221788
 .
 1597
 0.42
chr6_131318738_131318889 0.13 EPB41L2
 erythrocyte membrane protein band 4.1-like 2
 3094
 0.39
chr9_108051533_108051684 0.13 SLC44A1
 solute carrier family 44 (choline transporter), member 1
 44705
 0.19
chr4_81146676_81146827 0.13 PRDM8
 PR domain containing 8
 28093
 0.18
chr9_33819892_33820555 0.13 RP11-133O22.6
1430
 0.28
chr12_78482113_78482264 0.13 RP11-136F16.1
3329
 0.34
chr2_111828955_111829320 0.13 AC096670.3
42625
 0.17
chr9_115321849_115322000 0.13 C9orf147
 chromosome 9 open reading frame 147
 72440
 0.1
chr15_48894741_48894892 0.13 FBN1
 fibrillin 1
 43102
 0.18
chr1_52024489_52024927 0.13 OSBPL9
 oxysterol binding protein-like 9
 18143
 0.15
chr1_183851022_183851347 0.13 COLGALT2
 collagen beta(1-O)galactosyltransferase 2
 64568
 0.12
chr13_80510337_80510488 0.13 SPRY2
 sprouty homolog 2 (Drosophila)
 403382
 0.01
chr16_74499506_74499657 0.12 ENSG00000207525
 .
 1695
 0.33
chr5_122461018_122461169 0.12 AC106786.1
35099
 0.14
chr1_11238617_11238768 0.12 ENSG00000271794
 .
 9022
 0.12
chr7_72618452_72618603 0.12 NCF1B
 neutrophil cytosolic factor 1B pseudogene
 16084
 0.17
chr2_65065663_65065834 0.12 ENSG00000199964
 .
 4457
 0.21
chr13_97769047_97769198 0.12 ENSG00000238522
 .
 59489
 0.14
chr10_63734512_63734894 0.12 ENSG00000221272
 .
 47926
 0.17
chr9_111396920_111397071 0.12 ACTL7B
 actin-like 7B
 222244
 0.02
chr11_65259042_65259542 0.12 SCYL1
 SCY1-like 1 (S. cerevisiae)
 33256
 0.08
chr3_112817241_112817392 0.12 ENSG00000238593
 .
 5944
 0.21
chr6_154730400_154730551 0.12 CNKSR3
 CNKSR family member 3
 21154
 0.25
chrX_19593273_19593424 0.12 MAP3K15
 mitogen-activated protein kinase kinase kinase 15
 59969
 0.14
chr12_52182216_52182367 0.12 AC068987.1
 HCG1997999; cDNA FLJ33996 fis, clone DFNES2008881
 21498
 0.2
chr3_128914264_128914631 0.12 CNBP
 CCHC-type zinc finger, nucleic acid binding protein
 11682
 0.14
chr10_74498015_74498488 0.12 ENSG00000266719
 .
 17464
 0.16
chr3_57198236_57199040 0.12 IL17RD
 interleukin 17 receptor D
 765
 0.66
chr18_46460191_46460800 0.12 SMAD7
 SMAD family member 7
 14380
 0.24
chr14_69516631_69516869 0.12 ACTN1-AS1
 ACTN1 antisense RNA 1
 69992
 0.1
chr21_27298260_27298560 0.12 ENSG00000233783
 .
 7963
 0.22
chr15_57052440_57052789 0.12 ZNF280D
 zinc finger protein 280D
 26330
 0.25
chr2_36757574_36758239 0.12 RP11-78I14.1
17031
 0.17
chr1_235053615_235054079 0.12 ENSG00000239690
 .
 13914
 0.26
chr11_87156993_87157144 0.12 ENSG00000223015
 .
 160607
 0.04
chr5_88851937_88852088 0.12 MEF2C-AS1
 MEF2C antisense RNA 1
 137388
 0.05
chr15_70995885_70996036 0.12 UACA
 uveal autoantigen with coiled-coil domains and ankyrin repeats
 346
 0.92
chr16_82104529_82104680 0.12 HSD17B2
 hydroxysteroid (17-beta) dehydrogenase 2
 2722
 0.25
chr1_143991136_143991416 0.12 SRGAP2B
 SLIT-ROBO Rho GTPase activating protein 2B
 75034
 0.1
chr15_62465219_62465370 0.12 C2CD4B
 C2 calcium-dependent domain containing 4B
 7812
 0.23
chr5_149318448_149318662 0.12 ENSG00000200334
 .
 1139
 0.42
chr6_130004534_130005262 0.12 ARHGAP18
 Rho GTPase activating protein 18
 26472
 0.23
chr3_137762283_137762711 0.12 DZIP1L
 DAZ interacting zinc finger protein 1-like
 23985
 0.17
chr17_36433052_36433525 0.12 RP11-1407O15.2
 TBC1 domain family member 3
 11447
 0.15
chr3_8493806_8493957 0.12 LMCD1-AS1
 LMCD1 antisense RNA 1 (head to head)
 49403
 0.14
chr18_22878825_22879093 0.12 CTD-2006O16.2
3131
 0.37
chr15_66910964_66911559 0.12 RP11-321F6.1
 HCG2003567; Uncharacterized protein
 36733
 0.12
chr11_12188353_12189067 0.12 MICAL2
 microtubule associated monooxygenase, calponin and LIM domain containing 2
 5007
 0.29
chr10_127836908_127837102 0.12 ENSG00000222740
 .
 2854
 0.38
chr10_95574063_95574214 0.12 LGI1
 leucine-rich, glioma inactivated 1
 56460
 0.13
chr8_25771009_25771433 0.12 EBF2
 early B-cell factor 2
 25789
 0.27
chr4_110622784_110623524 0.12 CASP6
 caspase 6, apoptosis-related cysteine peptidase
 851
 0.59
chr11_73990200_73990857 0.12 ENSG00000206913
 .
 26931
 0.14
chr4_146725571_146725722 0.12 RP11-181K12.2
28624
 0.18
chr3_169491635_169492650 0.11 MYNN
 myoneurin
 89
 0.93
chr2_109860627_109860778 0.11 ENSG00000265965
 .
 69379
 0.12
chr16_72997806_72997957 0.11 ENSG00000221799
 .
 20875
 0.21
chr3_159554251_159554402 0.11 SCHIP1
 schwannomin interacting protein 1
 3324
 0.23
chr9_95300201_95300387 0.11 ECM2
 extracellular matrix protein 2, female organ and adipocyte specific
 1357
 0.42
chr6_34982238_34982465 0.11 TCP11
 t-complex 11, testis-specific
 106471
 0.06
chr4_119902260_119902411 0.11 SYNPO2
 synaptopodin 2
 42291
 0.19
chr12_50589962_50590113 0.11 LIMA1
 LIM domain and actin binding 1
 4593
 0.13
chr6_7204654_7204805 0.11 ENSG00000201483
 .
 16810
 0.18
chr3_156979212_156979363 0.11 ENSG00000243176
 .
 24662
 0.21
chr2_174889480_174890119 0.11 SP3
 Sp3 transcription factor
 59369
 0.15
chr2_74803113_74803707 0.11 LOXL3
 lysyl oxidase-like 3
 20593
 0.09
chr7_91655297_91655448 0.11 AKAP9
 A kinase (PRKA) anchor protein 9
 44080
 0.16
chr20_9072914_9073065 0.11 PLCB4
 phospholipase C, beta 4
 23241
 0.22
chr15_90224200_90224351 0.11 PLIN1
 perilipin 1
 1617
 0.24
chr2_238001181_238001332 0.11 COPS8
 COP9 signalosome subunit 8
 6670
 0.2
chr6_14136423_14136788 0.11 CD83
 CD83 molecule
 18733
 0.23
chr7_107255273_107255591 0.11 ENSG00000238832
 .
 11624
 0.14
chr5_124241911_124242195 0.11 ZNF608
 zinc finger protein 608
 157553
 0.04
chr1_222217681_222217979 0.11 ENSG00000212094
 .
 31398
 0.25
chr14_92864210_92864675 0.11 SLC24A4
 solute carrier family 24 (sodium/potassium/calcium exchanger), member 4
 10281
 0.28
chr21_30166964_30167115 0.11 ENSG00000251894
 .
 51509
 0.16
chr2_196359431_196359582 0.11 ENSG00000202206
 .
 19254
 0.27
chr3_118894860_118895154 0.11 UPK1B
 uroplakin 1B
 2560
 0.22
chr19_19097284_19097435 0.11 AC004447.2
4343
 0.14
chr11_74160265_74160482 0.11 RP11-702H23.6
6020
 0.14
chr5_93768337_93768488 0.11 KIAA0825
 KIAA0825
 104419
 0.07
chr6_117770708_117770859 0.11 RP1-92C8.3
3905
 0.17
chr9_94579747_94580327 0.11 ROR2
 receptor tyrosine kinase-like orphan receptor 2
 131125
 0.05
chr2_197345285_197345550 0.11 HECW2
 HECT, C2 and WW domain containing E3 ubiquitin protein ligase 2
 111918
 0.06
chr14_74533385_74533536 0.11 ALDH6A1
 aldehyde dehydrogenase 6 family, member A1
 2501
 0.22
chr8_20233157_20233440 0.11 LZTS1
 leucine zipper, putative tumor suppressor 1
 71824
 0.11
chr20_4879353_4879628 0.11 SLC23A2
 solute carrier family 23 (ascorbic acid transporter), member 2
 803
 0.62
chr8_38831032_38831302 0.11 HTRA4
 HtrA serine peptidase 4
 516
 0.5
chr13_110761676_110761827 0.11 ENSG00000265885
 .
 11253
 0.3
chr1_58861905_58862056 0.11 OMA1
 OMA1 zinc metallopeptidase
 142510
 0.04
chr3_149160811_149161262 0.11 TM4SF4
 transmembrane 4 L six family member 4
 30725
 0.16
chr6_113203227_113203573 0.11 ENSG00000201386
 .
 89295
 0.1
chr10_71232490_71232954 0.11 TSPAN15
 tetraspanin 15
 10902
 0.21
chr11_15989853_15990583 0.11 CTD-3096P4.1
54518
 0.18
chr6_138052819_138053031 0.11 ENSG00000216097
 .
 14840
 0.24
chr9_124009409_124009697 0.11 GSN
 gelsolin
 20785
 0.13
chr12_109245220_109245638 0.11 SSH1
 slingshot protein phosphatase 1
 5930
 0.16

Histogram of CRE-TSS distances for CREs targeted by :

Histogram of

Rank distribution of CRE target scores:

Histogram of target CRE score.

Distribution of target CREs across different genomic regions:

Weighted Piechart of Weighted Piechart of Weighted Piechart of

Network of associatons between targets according to the STRING database.

First level regulatory network of SOX10_SOX15

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0071694 sequestering of extracellular ligand from receptor(GO:0035581) sequestering of TGFbeta in extracellular matrix(GO:0035583) protein localization to extracellular region(GO:0071692) maintenance of protein location in extracellular region(GO:0071694) extracellular regulation of signal transduction(GO:1900115) extracellular negative regulation of signal transduction(GO:1900116)
0.1 0.2 GO:0060831 smoothened signaling pathway involved in dorsal/ventral neural tube patterning(GO:0060831)
0.1 0.3 GO:0060907 positive regulation of macrophage cytokine production(GO:0060907)
0.1 0.2 GO:0072201 negative regulation of mesenchymal cell proliferation(GO:0072201)
0.0 0.3 GO:0060997 dendritic spine morphogenesis(GO:0060997) regulation of dendritic spine morphogenesis(GO:0061001) dendritic spine organization(GO:0097061)
0.0 0.2 GO:0072010 renal filtration cell differentiation(GO:0061318) glomerular epithelium development(GO:0072010) glomerular visceral epithelial cell differentiation(GO:0072112) glomerular epithelial cell differentiation(GO:0072311)
0.0 0.2 GO:0071731 response to nitric oxide(GO:0071731)
0.0 0.1 GO:0032509 endosome transport via multivesicular body sorting pathway(GO:0032509)
0.0 0.2 GO:0006654 phosphatidic acid biosynthetic process(GO:0006654)
0.0 0.2 GO:0051124 synaptic growth at neuromuscular junction(GO:0051124)
0.0 0.2 GO:0048149 behavioral response to ethanol(GO:0048149)
0.0 0.1 GO:0007221 positive regulation of transcription of Notch receptor target(GO:0007221)
0.0 0.1 GO:0035385 Roundabout signaling pathway(GO:0035385)
0.0 0.1 GO:0032347 regulation of ketone biosynthetic process(GO:0010566) regulation of aldosterone metabolic process(GO:0032344) regulation of aldosterone biosynthetic process(GO:0032347)
0.0 0.1 GO:0010193 response to ozone(GO:0010193)
0.0 0.1 GO:0070050 neuron cellular homeostasis(GO:0070050)
0.0 0.2 GO:0007171 activation of transmembrane receptor protein tyrosine kinase activity(GO:0007171)
0.0 0.1 GO:0043589 skin morphogenesis(GO:0043589)
0.0 0.2 GO:0022617 extracellular matrix disassembly(GO:0022617)
0.0 0.1 GO:0060083 smooth muscle contraction involved in micturition(GO:0060083)
0.0 0.2 GO:0032430 positive regulation of phospholipase A2 activity(GO:0032430)
0.0 0.2 GO:0048625 myoblast fate commitment(GO:0048625)
0.0 0.1 GO:0048702 embryonic neurocranium morphogenesis(GO:0048702)
0.0 0.1 GO:0060750 epithelial cell proliferation involved in mammary gland duct elongation(GO:0060750)
0.0 0.1 GO:0045162 clustering of voltage-gated sodium channels(GO:0045162)
0.0 0.1 GO:0002551 mast cell chemotaxis(GO:0002551) regulation of mast cell chemotaxis(GO:0060753) positive regulation of mast cell chemotaxis(GO:0060754) mast cell migration(GO:0097531)
0.0 0.1 GO:0048845 venous blood vessel morphogenesis(GO:0048845)
0.0 0.1 GO:0009128 purine nucleoside monophosphate catabolic process(GO:0009128) ribonucleoside monophosphate catabolic process(GO:0009158) purine ribonucleoside monophosphate catabolic process(GO:0009169)
0.0 0.1 GO:0006663 platelet activating factor biosynthetic process(GO:0006663)
0.0 0.1 GO:0060394 negative regulation of pathway-restricted SMAD protein phosphorylation(GO:0060394)
0.0 0.1 GO:0006703 estrogen biosynthetic process(GO:0006703)
0.0 0.1 GO:0051305 chromosome movement towards spindle pole(GO:0051305)
0.0 0.0 GO:0055098 response to low-density lipoprotein particle(GO:0055098)
0.0 0.1 GO:0002043 blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:0002043)
0.0 0.1 GO:0070874 negative regulation of glycogen metabolic process(GO:0070874)
0.0 0.0 GO:0061042 vascular wound healing(GO:0061042) regulation of vascular wound healing(GO:0061043)
0.0 0.1 GO:0001996 positive regulation of heart rate by epinephrine-norepinephrine(GO:0001996)
0.0 0.1 GO:0008215 spermine metabolic process(GO:0008215)
0.0 0.1 GO:0046504 ether lipid biosynthetic process(GO:0008611) glycerol ether biosynthetic process(GO:0046504) ether biosynthetic process(GO:1901503)
0.0 0.1 GO:0035234 ectopic germ cell programmed cell death(GO:0035234)
0.0 0.1 GO:0001547 antral ovarian follicle growth(GO:0001547)
0.0 0.1 GO:0006651 diacylglycerol biosynthetic process(GO:0006651)
0.0 0.1 GO:1903521 apoptotic process involved in mammary gland involution(GO:0060057) positive regulation of apoptotic process involved in mammary gland involution(GO:0060058) positive regulation of apoptotic process involved in morphogenesis(GO:1902339) regulation of mammary gland involution(GO:1903519) positive regulation of mammary gland involution(GO:1903521) positive regulation of apoptotic process involved in development(GO:1904747)
0.0 0.1 GO:0030579 ubiquitin-dependent SMAD protein catabolic process(GO:0030579)
0.0 0.1 GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.0 0.1 GO:0014012 peripheral nervous system axon regeneration(GO:0014012)
0.0 0.2 GO:1901532 regulation of megakaryocyte differentiation(GO:0045652) regulation of hematopoietic progenitor cell differentiation(GO:1901532)
0.0 0.1 GO:0033173 calcineurin-NFAT signaling cascade(GO:0033173)
0.0 0.0 GO:0061298 retina vasculature development in camera-type eye(GO:0061298) retina vasculature morphogenesis in camera-type eye(GO:0061299)
0.0 0.1 GO:0017121 phospholipid scrambling(GO:0017121)
0.0 0.1 GO:0071318 cellular response to ATP(GO:0071318)
0.0 0.0 GO:0060242 contact inhibition(GO:0060242)
0.0 0.1 GO:0061302 smooth muscle cell-matrix adhesion(GO:0061302)
0.0 0.1 GO:0009051 pentose-phosphate shunt, oxidative branch(GO:0009051)
0.0 0.0 GO:0070427 nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070427)
0.0 0.0 GO:0002604 dendritic cell antigen processing and presentation(GO:0002468) regulation of dendritic cell antigen processing and presentation(GO:0002604)
0.0 0.0 GO:0030011 maintenance of cell polarity(GO:0030011)
0.0 0.3 GO:0045600 positive regulation of fat cell differentiation(GO:0045600)
0.0 0.0 GO:0071502 cellular response to temperature stimulus(GO:0071502)
0.0 0.0 GO:0002540 arachidonic acid metabolite production involved in inflammatory response(GO:0002538) leukotriene production involved in inflammatory response(GO:0002540)
0.0 0.0 GO:0060437 lung growth(GO:0060437)
0.0 0.1 GO:0050872 white fat cell differentiation(GO:0050872)
0.0 0.1 GO:0051014 actin filament severing(GO:0051014)
0.0 0.1 GO:0006991 response to sterol depletion(GO:0006991)
0.0 0.1 GO:0031340 positive regulation of vesicle fusion(GO:0031340)
0.0 0.1 GO:0072383 plus-end-directed vesicle transport along microtubule(GO:0072383) plus-end-directed organelle transport along microtubule(GO:0072386)
0.0 0.1 GO:0008228 opsonization(GO:0008228)
0.0 0.0 GO:0031665 negative regulation of lipopolysaccharide-mediated signaling pathway(GO:0031665)
0.0 0.1 GO:0048245 eosinophil chemotaxis(GO:0048245) eosinophil migration(GO:0072677)
0.0 0.1 GO:0006927 obsolete transformed cell apoptotic process(GO:0006927)
0.0 0.1 GO:0045662 negative regulation of myoblast differentiation(GO:0045662)
0.0 0.1 GO:0007185 transmembrane receptor protein tyrosine phosphatase signaling pathway(GO:0007185)
0.0 0.1 GO:0033630 positive regulation of cell adhesion mediated by integrin(GO:0033630)
0.0 0.0 GO:0032048 phosphatidylglycerol biosynthetic process(GO:0006655) cardiolipin metabolic process(GO:0032048) cardiolipin biosynthetic process(GO:0032049) phosphatidylglycerol metabolic process(GO:0046471)
0.0 0.0 GO:0006824 cobalt ion transport(GO:0006824)
0.0 0.1 GO:0051769 nitric-oxide synthase biosynthetic process(GO:0051767) regulation of nitric-oxide synthase biosynthetic process(GO:0051769) positive regulation of nitric-oxide synthase biosynthetic process(GO:0051770)
0.0 0.1 GO:0060638 mesenchymal-epithelial cell signaling(GO:0060638)
0.0 0.0 GO:0010757 negative regulation of plasminogen activation(GO:0010757)
0.0 0.1 GO:0030091 protein repair(GO:0030091)
0.0 0.1 GO:2000095 regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000095)
0.0 0.3 GO:0006195 purine nucleotide catabolic process(GO:0006195)
0.0 0.1 GO:0032467 positive regulation of cytokinesis(GO:0032467)
0.0 0.1 GO:0006108 malate metabolic process(GO:0006108)
0.0 0.1 GO:0006572 tyrosine catabolic process(GO:0006572)
0.0 0.0 GO:0019859 pyrimidine nucleobase catabolic process(GO:0006208) thymine catabolic process(GO:0006210) thymine metabolic process(GO:0019859) nucleobase catabolic process(GO:0046113)
0.0 0.0 GO:0046121 deoxyribonucleoside catabolic process(GO:0046121)
0.0 0.1 GO:0009396 folic acid-containing compound biosynthetic process(GO:0009396)
0.0 0.0 GO:0005981 regulation of glycogen catabolic process(GO:0005981)
0.0 0.0 GO:0032288 myelin assembly(GO:0032288)
0.0 0.0 GO:0021670 lateral ventricle development(GO:0021670)
0.0 0.0 GO:0070672 response to interleukin-15(GO:0070672)
0.0 0.0 GO:0001845 phagolysosome assembly(GO:0001845) phagosome maturation(GO:0090382)
0.0 0.0 GO:0070172 positive regulation of tooth mineralization(GO:0070172)
0.0 0.0 GO:0006931 substrate-dependent cell migration, cell attachment to substrate(GO:0006931)
0.0 0.1 GO:0008655 pyrimidine-containing compound salvage(GO:0008655) pyrimidine nucleoside salvage(GO:0043097)
0.0 0.1 GO:0006527 arginine catabolic process(GO:0006527)
0.0 0.0 GO:0072526 pyridine-containing compound catabolic process(GO:0072526)
0.0 0.0 GO:0045657 positive regulation of monocyte differentiation(GO:0045657)
0.0 0.0 GO:1901889 negative regulation of focal adhesion assembly(GO:0051895) negative regulation of cell junction assembly(GO:1901889) negative regulation of adherens junction organization(GO:1903392)
0.0 0.1 GO:0033137 negative regulation of peptidyl-serine phosphorylation(GO:0033137)
0.0 0.1 GO:0032780 negative regulation of ATPase activity(GO:0032780)
0.0 0.0 GO:0051771 negative regulation of nitric-oxide synthase biosynthetic process(GO:0051771)
0.0 0.1 GO:0019852 L-ascorbic acid metabolic process(GO:0019852)
0.0 0.1 GO:0046487 glyoxylate metabolic process(GO:0046487)
0.0 0.1 GO:0006930 substrate-dependent cell migration, cell extension(GO:0006930)
0.0 0.1 GO:0033962 cytoplasmic mRNA processing body assembly(GO:0033962)
0.0 0.1 GO:0015840 urea transport(GO:0015840)
0.0 0.0 GO:0046485 ether lipid metabolic process(GO:0046485)
0.0 0.0 GO:0034638 phosphatidylcholine catabolic process(GO:0034638)
0.0 0.1 GO:0090162 establishment of epithelial cell polarity(GO:0090162)
0.0 0.1 GO:0090023 positive regulation of neutrophil chemotaxis(GO:0090023) positive regulation of neutrophil migration(GO:1902624)
0.0 0.1 GO:0006590 thyroid hormone generation(GO:0006590)
0.0 0.0 GO:0060528 secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development(GO:0060528)
0.0 0.1 GO:0090136 epithelial cell-cell adhesion(GO:0090136)
0.0 0.1 GO:0043306 positive regulation of mast cell activation involved in immune response(GO:0033008) positive regulation of leukocyte degranulation(GO:0043302) positive regulation of mast cell degranulation(GO:0043306)
0.0 0.0 GO:0010842 retina layer formation(GO:0010842)
0.0 0.0 GO:0016103 diterpenoid catabolic process(GO:0016103) terpenoid catabolic process(GO:0016115) retinoic acid catabolic process(GO:0034653)
0.0 0.1 GO:0036296 response to increased oxygen levels(GO:0036296) response to hyperoxia(GO:0055093)
0.0 0.1 GO:0097035 regulation of membrane lipid distribution(GO:0097035)
0.0 0.0 GO:0071681 response to indole-3-methanol(GO:0071680) cellular response to indole-3-methanol(GO:0071681)
0.0 0.1 GO:0006048 UDP-N-acetylglucosamine biosynthetic process(GO:0006048)
0.0 0.1 GO:0015871 choline transport(GO:0015871)
0.0 0.0 GO:0033147 negative regulation of intracellular estrogen receptor signaling pathway(GO:0033147)
0.0 0.1 GO:0019369 arachidonic acid metabolic process(GO:0019369)
0.0 0.0 GO:2000542 negative regulation of gastrulation(GO:2000542)
0.0 0.1 GO:0015889 cobalamin transport(GO:0015889)
0.0 0.1 GO:0031641 regulation of myelination(GO:0031641)
0.0 0.1 GO:0048821 erythrocyte development(GO:0048821) myeloid cell development(GO:0061515)
0.0 0.1 GO:0030321 transepithelial chloride transport(GO:0030321)
0.0 0.1 GO:0002138 retinoic acid biosynthetic process(GO:0002138) diterpenoid biosynthetic process(GO:0016102)
0.0 0.1 GO:0046855 phosphorylated carbohydrate dephosphorylation(GO:0046838) inositol phosphate dephosphorylation(GO:0046855)
0.0 0.1 GO:0016266 O-glycan processing(GO:0016266)
0.0 0.1 GO:0048853 forebrain morphogenesis(GO:0048853)
0.0 0.1 GO:0007016 cytoskeletal anchoring at plasma membrane(GO:0007016)
0.0 0.0 GO:0050774 negative regulation of dendrite morphogenesis(GO:0050774)
0.0 0.1 GO:0040019 positive regulation of embryonic development(GO:0040019)
0.0 0.1 GO:0045647 negative regulation of erythrocyte differentiation(GO:0045647)
0.0 0.0 GO:0007500 mesodermal cell fate determination(GO:0007500)
0.0 0.0 GO:0045163 clustering of voltage-gated potassium channels(GO:0045163)
0.0 0.0 GO:0009448 gamma-aminobutyric acid metabolic process(GO:0009448)
0.0 0.1 GO:0019695 choline metabolic process(GO:0019695)
0.0 0.1 GO:0046835 carbohydrate phosphorylation(GO:0046835)
0.0 0.3 GO:0010811 positive regulation of cell-substrate adhesion(GO:0010811)
0.0 0.0 GO:0032959 inositol trisphosphate biosynthetic process(GO:0032959)
0.0 0.0 GO:0060431 primary lung bud formation(GO:0060431)
0.0 0.0 GO:0002430 complement receptor mediated signaling pathway(GO:0002430)
0.0 0.0 GO:0016576 histone dephosphorylation(GO:0016576)
0.0 0.1 GO:0046426 negative regulation of JAK-STAT cascade(GO:0046426) negative regulation of STAT cascade(GO:1904893)
0.0 0.1 GO:0019363 pyridine nucleotide biosynthetic process(GO:0019363)
0.0 0.1 GO:0006206 pyrimidine nucleobase metabolic process(GO:0006206)
0.0 0.1 GO:0034755 iron ion transmembrane transport(GO:0034755)
0.0 0.1 GO:0035329 hippo signaling(GO:0035329)
0.0 0.0 GO:0046512 diol biosynthetic process(GO:0034312) sphingosine biosynthetic process(GO:0046512)
0.0 0.0 GO:0019919 peptidyl-arginine methylation, to asymmetrical-dimethyl arginine(GO:0019919)
0.0 0.0 GO:0015793 glycerol transport(GO:0015793)
0.0 0.0 GO:0002023 reduction of food intake in response to dietary excess(GO:0002023)
0.0 0.0 GO:0002283 neutrophil activation involved in immune response(GO:0002283) neutrophil degranulation(GO:0043312)
0.0 0.1 GO:0060259 regulation of feeding behavior(GO:0060259)
0.0 0.0 GO:0002689 negative regulation of leukocyte chemotaxis(GO:0002689)
0.0 0.0 GO:0045747 positive regulation of Notch signaling pathway(GO:0045747)
0.0 0.0 GO:0048631 regulation of skeletal muscle tissue growth(GO:0048631)
0.0 0.1 GO:0009629 response to gravity(GO:0009629)
0.0 0.0 GO:0006391 transcription initiation from mitochondrial promoter(GO:0006391)
0.0 0.1 GO:0010886 positive regulation of cholesterol storage(GO:0010886)
0.0 0.2 GO:0018149 peptide cross-linking(GO:0018149)
0.0 0.1 GO:0048712 negative regulation of astrocyte differentiation(GO:0048712)
0.0 0.0 GO:0016093 polyprenol metabolic process(GO:0016093) dolichol metabolic process(GO:0019348)
0.0 0.0 GO:0046882 negative regulation of follicle-stimulating hormone secretion(GO:0046882)
0.0 0.1 GO:0002566 somatic diversification of immune receptors via somatic mutation(GO:0002566) somatic hypermutation of immunoglobulin genes(GO:0016446)
0.0 0.0 GO:0000492 small nucleolar ribonucleoprotein complex assembly(GO:0000491) box C/D snoRNP assembly(GO:0000492)
0.0 0.0 GO:0002328 pro-B cell differentiation(GO:0002328)
0.0 0.0 GO:0055089 fatty acid homeostasis(GO:0055089)
0.0 0.0 GO:0001714 endodermal cell fate commitment(GO:0001711) endodermal cell fate specification(GO:0001714) endodermal cell differentiation(GO:0035987) regulation of endodermal cell fate specification(GO:0042663) regulation of endodermal cell differentiation(GO:1903224)
0.0 0.0 GO:0046501 protoporphyrinogen IX metabolic process(GO:0046501)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0043259 laminin-10 complex(GO:0043259)
0.0 0.2 GO:0016342 catenin complex(GO:0016342)
0.0 0.3 GO:0005614 interstitial matrix(GO:0005614)
0.0 0.1 GO:0032449 CBM complex(GO:0032449)
0.0 0.1 GO:0005589 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.0 0.1 GO:0030056 hemidesmosome(GO:0030056)
0.0 0.1 GO:0071664 catenin-TCF7L2 complex(GO:0071664)
0.0 0.1 GO:0005862 muscle thin filament tropomyosin(GO:0005862)
0.0 0.1 GO:0033268 node of Ranvier(GO:0033268)
0.0 0.2 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.0 0.1 GO:0030934 anchoring collagen complex(GO:0030934)
0.0 0.2 GO:0098642 network-forming collagen trimer(GO:0098642) collagen network(GO:0098645)
0.0 0.0 GO:0098651 basement membrane collagen trimer(GO:0098651)
0.0 0.1 GO:0044298 neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.0 0.1 GO:0030128 AP-2 adaptor complex(GO:0030122) clathrin coat of endocytic vesicle(GO:0030128)
0.0 0.1 GO:0005828 kinetochore microtubule(GO:0005828)
0.0 0.1 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.0 0.1 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.0 0.1 GO:0035253 ciliary rootlet(GO:0035253)
0.0 0.2 GO:0030315 T-tubule(GO:0030315)
0.0 0.1 GO:0001527 microfibril(GO:0001527)
0.0 0.1 GO:0042405 nuclear inclusion body(GO:0042405)
0.0 0.1 GO:0030312 external encapsulating structure(GO:0030312)
0.0 0.0 GO:0045254 pyruvate dehydrogenase complex(GO:0045254)
0.0 0.5 GO:0005884 actin filament(GO:0005884)
0.0 0.1 GO:0030127 COPII vesicle coat(GO:0030127)
0.0 0.1 GO:0043256 laminin complex(GO:0043256)
0.0 0.1 GO:0043020 NADPH oxidase complex(GO:0043020)
0.0 0.1 GO:0071437 invadopodium(GO:0071437)
0.0 0.1 GO:0000145 exocyst(GO:0000145)
0.0 0.1 GO:0030877 beta-catenin destruction complex(GO:0030877)
0.0 0.0 GO:0043625 delta DNA polymerase complex(GO:0043625)
0.0 0.0 GO:0005593 FACIT collagen trimer(GO:0005593)
0.0 0.0 GO:0000137 Golgi cis cisterna(GO:0000137)
0.0 0.2 GO:0005811 lipid particle(GO:0005811)
0.0 0.1 GO:0031143 pseudopodium(GO:0031143)
0.0 0.1 GO:0031232 extrinsic component of external side of plasma membrane(GO:0031232)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.1 0.2 GO:0001159 RNA polymerase II core promoter proximal region sequence-specific DNA binding(GO:0000978) core promoter proximal region sequence-specific DNA binding(GO:0000987) core promoter proximal region DNA binding(GO:0001159)
0.0 0.2 GO:0005010 insulin-like growth factor-activated receptor activity(GO:0005010)
0.0 0.3 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.0 0.1 GO:0005006 epidermal growth factor-activated receptor activity(GO:0005006)
0.0 0.2 GO:0051637 obsolete Gram-positive bacterial cell surface binding(GO:0051637)
0.0 0.2 GO:0004470 malic enzyme activity(GO:0004470)
0.0 0.3 GO:0004908 interleukin-1 receptor activity(GO:0004908)
0.0 0.1 GO:0070052 collagen V binding(GO:0070052)
0.0 0.1 GO:0004720 protein-lysine 6-oxidase activity(GO:0004720)
0.0 0.1 GO:0032450 maltose alpha-glucosidase activity(GO:0032450)
0.0 0.1 GO:0045545 syndecan binding(GO:0045545)
0.0 0.1 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.0 0.1 GO:0015204 urea transmembrane transporter activity(GO:0015204)
0.0 0.1 GO:0016724 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.0 0.1 GO:0004117 calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117)
0.0 0.1 GO:0016509 long-chain-3-hydroxyacyl-CoA dehydrogenase activity(GO:0016509)
0.0 0.1 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.0 0.1 GO:0004321 fatty-acyl-CoA synthase activity(GO:0004321)
0.0 0.1 GO:0015016 [heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
0.0 0.1 GO:0033130 acetylcholine receptor binding(GO:0033130)
0.0 0.1 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
0.0 0.2 GO:0017166 vinculin binding(GO:0017166)
0.0 0.2 GO:0045294 alpha-catenin binding(GO:0045294)
0.0 0.1 GO:0004461 lactose synthase activity(GO:0004461)
0.0 0.1 GO:0042805 actinin binding(GO:0042805)
0.0 0.1 GO:0048027 mRNA 5'-UTR binding(GO:0048027)
0.0 0.1 GO:0070696 transmembrane receptor protein serine/threonine kinase binding(GO:0070696)
0.0 0.3 GO:0005523 tropomyosin binding(GO:0005523)
0.0 0.1 GO:0017128 phospholipid scramblase activity(GO:0017128)
0.0 0.1 GO:0003680 AT DNA binding(GO:0003680)
0.0 0.1 GO:0005172 vascular endothelial growth factor receptor binding(GO:0005172)
0.0 0.1 GO:0032052 bile acid binding(GO:0032052)
0.0 0.1 GO:0004800 thyroxine 5'-deiodinase activity(GO:0004800)
0.0 0.1 GO:0033743 peptide-methionine (R)-S-oxide reductase activity(GO:0033743)
0.0 0.1 GO:0005017 platelet-derived growth factor-activated receptor activity(GO:0005017)
0.0 0.1 GO:0030297 transmembrane receptor protein tyrosine kinase activator activity(GO:0030297)
0.0 0.1 GO:0042808 obsolete neuronal Cdc2-like kinase binding(GO:0042808)
0.0 0.2 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.0 0.1 GO:0034056 estrogen response element binding(GO:0034056)
0.0 0.1 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.0 0.3 GO:0008395 steroid hydroxylase activity(GO:0008395)
0.0 0.1 GO:0004082 bisphosphoglycerate mutase activity(GO:0004082) bisphosphoglycerate 2-phosphatase activity(GO:0004083) phosphoglycerate mutase activity(GO:0004619)
0.0 0.1 GO:0004849 uridine kinase activity(GO:0004849)
0.0 0.1 GO:0016421 CoA carboxylase activity(GO:0016421)
0.0 0.1 GO:0070290 N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.0 0.1 GO:0004982 N-formyl peptide receptor activity(GO:0004982)
0.0 0.1 GO:0017159 pantetheine hydrolase activity(GO:0017159)
0.0 0.1 GO:0047184 1-acylglycerophosphocholine O-acyltransferase activity(GO:0047184)
0.0 0.1 GO:0004616 phosphogluconate dehydrogenase (decarboxylating) activity(GO:0004616)
0.0 0.2 GO:0019864 IgG binding(GO:0019864)
0.0 0.0 GO:0070097 delta-catenin binding(GO:0070097)
0.0 0.1 GO:0001875 lipopolysaccharide receptor activity(GO:0001875)
0.0 0.1 GO:0004597 peptide-aspartate beta-dioxygenase activity(GO:0004597)
0.0 0.0 GO:0004515 nicotinamide-nucleotide adenylyltransferase activity(GO:0000309) nicotinate-nucleotide adenylyltransferase activity(GO:0004515)
0.0 0.1 GO:0030274 LIM domain binding(GO:0030274)
0.0 0.0 GO:0002162 dystroglycan binding(GO:0002162)
0.0 0.0 GO:0008475 procollagen-lysine 5-dioxygenase activity(GO:0008475)
0.0 0.1 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
0.0 0.0 GO:0016623 oxidoreductase activity, acting on the aldehyde or oxo group of donors, oxygen as acceptor(GO:0016623)
0.0 0.1 GO:0030492 hemoglobin binding(GO:0030492)
0.0 0.1 GO:0047035 testosterone dehydrogenase (NAD+) activity(GO:0047035)
0.0 0.1 GO:0004300 enoyl-CoA hydratase activity(GO:0004300)
0.0 0.1 GO:0004523 RNA-DNA hybrid ribonuclease activity(GO:0004523)
0.0 0.1 GO:0008046 axon guidance receptor activity(GO:0008046)
0.0 0.2 GO:0004622 lysophospholipase activity(GO:0004622)
0.0 0.2 GO:0035035 histone acetyltransferase binding(GO:0035035)
0.0 0.0 GO:0070644 vitamin D response element binding(GO:0070644)
0.0 0.0 GO:0016802 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.0 0.0 GO:0042577 lipid phosphatase activity(GO:0042577)
0.0 0.1 GO:0048185 activin binding(GO:0048185)
0.0 0.2 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.0 0.1 GO:0016175 superoxide-generating NADPH oxidase activity(GO:0016175)
0.0 0.1 GO:0004791 thioredoxin-disulfide reductase activity(GO:0004791)
0.0 0.1 GO:0005534 galactose binding(GO:0005534)
0.0 0.1 GO:0001968 fibronectin binding(GO:0001968)
0.0 0.1 GO:0046790 virion binding(GO:0046790)
0.0 0.1 GO:0050998 nitric-oxide synthase binding(GO:0050998)
0.0 0.1 GO:0042285 UDP-xylosyltransferase activity(GO:0035252) xylosyltransferase activity(GO:0042285)
0.0 0.1 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.0 0.1 GO:0015556 C4-dicarboxylate transmembrane transporter activity(GO:0015556)
0.0 0.1 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0 0.0 GO:0005250 A-type (transient outward) potassium channel activity(GO:0005250)
0.0 0.1 GO:0008179 adenylate cyclase binding(GO:0008179)
0.0 0.0 GO:0008113 peptide-methionine (S)-S-oxide reductase activity(GO:0008113)
0.0 0.0 GO:0008898 S-adenosylmethionine-homocysteine S-methyltransferase activity(GO:0008898)
0.0 0.0 GO:0016886 ligase activity, forming phosphoric ester bonds(GO:0016886)
0.0 0.0 GO:0016715 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen(GO:0016715)
0.0 0.1 GO:0005536 glucose binding(GO:0005536)
0.0 0.4 GO:0005518 collagen binding(GO:0005518)
0.0 0.0 GO:0004111 creatine kinase activity(GO:0004111)
0.0 0.1 GO:0016813 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
0.0 0.0 GO:0004965 G-protein coupled GABA receptor activity(GO:0004965)
0.0 0.1 GO:0070008 serine-type exopeptidase activity(GO:0070008)
0.0 0.0 GO:0005350 pyrimidine nucleobase transmembrane transporter activity(GO:0005350)
0.0 0.1 GO:0000339 RNA cap binding(GO:0000339)
0.0 0.1 GO:0004859 phospholipase inhibitor activity(GO:0004859)
0.0 0.0 GO:0051636 obsolete Gram-negative bacterial cell surface binding(GO:0051636)
0.0 0.0 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.0 0.0 GO:0033265 cholinesterase activity(GO:0004104) choline binding(GO:0033265)
0.0 0.0 GO:0005432 calcium:sodium antiporter activity(GO:0005432)
0.0 0.0 GO:0004875 complement receptor activity(GO:0004875)
0.0 0.0 GO:0016909 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.0 0.1 GO:0003993 acid phosphatase activity(GO:0003993)
0.0 0.0 GO:0005030 neurotrophin receptor activity(GO:0005030)
0.0 0.1 GO:0045296 cadherin binding(GO:0045296)
0.0 0.0 GO:0050544 arachidonic acid binding(GO:0050544)
0.0 0.1 GO:0034235 GPI anchor binding(GO:0034235)
0.0 0.0 GO:0034186 apolipoprotein A-I binding(GO:0034186)
0.0 0.0 GO:0008332 low voltage-gated calcium channel activity(GO:0008332)
0.0 0.0 GO:0003987 acetate-CoA ligase activity(GO:0003987)
0.0 0.1 GO:0022821 potassium ion antiporter activity(GO:0022821)
0.0 0.5 GO:0008009 chemokine activity(GO:0008009)
0.0 0.2 GO:0005242 inward rectifier potassium channel activity(GO:0005242)
0.0 0.1 GO:0030506 ankyrin binding(GO:0030506)
0.0 0.0 GO:0043515 kinetochore binding(GO:0043515)
0.0 0.0 GO:0000293 ferric-chelate reductase activity(GO:0000293)
0.0 0.1 GO:0008504 monoamine transmembrane transporter activity(GO:0008504)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 PID IGF1 PATHWAY IGF1 pathway
0.0 0.0 PID THROMBIN PAR4 PATHWAY PAR4-mediated thrombin signaling events
0.0 0.2 PID IL1 PATHWAY IL1-mediated signaling events
0.0 0.0 PID TRAIL PATHWAY TRAIL signaling pathway
0.0 0.0 PID A6B1 A6B4 INTEGRIN PATHWAY a6b1 and a6b4 Integrin signaling
0.0 0.0 PID GMCSF PATHWAY GMCSF-mediated signaling events
0.0 0.2 PID FGF PATHWAY FGF signaling pathway
0.0 0.0 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.0 0.4 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events
0.0 0.3 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.0 0.1 PID RET PATHWAY Signaling events regulated by Ret tyrosine kinase
0.0 0.5 NABA BASEMENT MEMBRANES Genes encoding structural components of basement membranes
0.0 0.0 PID PDGFRA PATHWAY PDGFR-alpha signaling pathway
0.0 0.0 SA PTEN PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 REACTOME SIGNALING BY FGFR Genes involved in Signaling by FGFR
0.0 0.4 REACTOME PURINE CATABOLISM Genes involved in Purine catabolism
0.0 0.2 REACTOME ADP SIGNALLING THROUGH P2RY12 Genes involved in ADP signalling through P2Y purinoceptor 12
0.0 0.0 REACTOME BILE ACID AND BILE SALT METABOLISM Genes involved in Bile acid and bile salt metabolism
0.0 0.5 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.0 0.6 REACTOME MYOGENESIS Genes involved in Myogenesis
0.0 0.2 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.0 0.2 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
0.0 0.2 REACTOME ENDOGENOUS STEROLS Genes involved in Endogenous sterols
0.0 0.2 REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the late endosome membrane
0.0 0.0 REACTOME INFLUENZA VIRAL RNA TRANSCRIPTION AND REPLICATION Genes involved in Influenza Viral RNA Transcription and Replication
0.0 0.3 REACTOME PYRIMIDINE METABOLISM Genes involved in Pyrimidine metabolism
0.0 0.0 REACTOME TRIGLYCERIDE BIOSYNTHESIS Genes involved in Triglyceride Biosynthesis
0.0 0.2 REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.0 0.2 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0 0.1 REACTOME SIGNAL ATTENUATION Genes involved in Signal attenuation
0.0 0.0 REACTOME ALPHA LINOLENIC ACID ALA METABOLISM Genes involved in alpha-linolenic acid (ALA) metabolism
0.0 0.0 REACTOME DOWNSTREAM SIGNAL TRANSDUCTION Genes involved in Downstream signal transduction
0.0 0.1 REACTOME TIE2 SIGNALING Genes involved in Tie2 Signaling