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ENCODE: H3K4me1 ChIP-Seq of primary human cells

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CREMA is a free online tool that recognizes most important transcription factors that change the chromatin state across different samples.

Results for SOX10_SOX15

Z-value: 0.89

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Transcription factors associated with SOX10_SOX15

Gene Symbol	Gene ID	Gene Info
SOX10 Ensembl NCBI GeneCards UniProt	ENSG00000100146.12	SOX10
SOX15 Ensembl NCBI GeneCards UniProt	ENSG00000129194.3	SOX15

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE	Gene	Distance	Association probability	Pearson corr. coef.	P-value	Plot
SOX10	chr22_38378877_38379028	469	0.664619	0.64	6.5e-02	Click!
SOX10	chr22_38378547_38378698	799	0.443869	0.29	4.5e-01	Click!
SOX10	chr22_38383217_38383368	137	0.880458	-0.09	8.2e-01	Click!
SOX10	chr22_38382918_38383069	436	0.557146	0.07	8.5e-01	Click!
SOX15	chr17_7494297_7494448	884	0.244711	0.57	1.1e-01	Click!
SOX15	chr17_7493992_7494161	588	0.393160	0.55	1.2e-01	Click!
SOX15	chr17_7491559_7492035	1593	0.117079	0.53	1.4e-01	Click!
SOX15	chr17_7491173_7491417	2095	0.087931	0.50	1.7e-01	Click!
SOX15	chr17_7492402_7492756	811	0.269600	0.35	3.6e-01	Click!

Activity of the SOX10_SOX15 motif across conditions

Conditions sorted by the z-value of the SOX10_SOX15 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE)	Target Score	Top associated gene	Gene Info	Distance of CRE to TSS	CRE/Gene association probability
chr17_76370784_76371498	0.27	PGS1	phosphatidylglycerophosphate synthase 1	3580	0.16
chr15_40081991_40082468	0.27	FSIP1	fibrous sheath interacting protein 1	7198	0.17
chr14_72014650_72014936	0.23	SIPA1L1	signal-induced proliferation-associated 1 like 1	18751	0.27
chr2_118981232_118982329	0.20	INSIG2	insulin induced gene 2	135730	0.05
chr12_14412980_14413356	0.20	ENSG00000251908	.	9893	0.22
chr9_33126556_33126826	0.20	B4GALT1	UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1	1506	0.36
chr3_171712617_171713197	0.19	FNDC3B	fibronectin type III domain containing 3B	44511	0.17
chr11_10680453_10681322	0.19	MRVI1	murine retrovirus integration site 1 homolog	6964	0.2
chr21_30557129_30557311	0.19	AF124730.4		2896	0.17
chr20_17631217_17631686	0.19	RRBP1	ribosome binding protein 1	9701	0.21
chr12_92683552_92683850	0.19	ENSG00000199895	.	119472	0.05
chr5_17223674_17224319	0.19	BASP1	brain abundant, membrane attached signal protein 1	6327	0.19
chr2_100630949_100631235	0.19	AFF3	AF4/FMR2 family, member 3	89900	0.09
chr16_72405306_72405606	0.19	ENSG00000207514	.	5147	0.31
chr7_80263577_80263846	0.18	CD36	CD36 molecule (thrombospondin receptor)	4249	0.35
chr10_22605642_22606566	0.18	COMMD3	COMM domain containing 3	730	0.4
chr20_9389511_9389662	0.18	PLCB4	phospholipase C, beta 4	101139	0.07
chr6_127522710_127522861	0.18	RNF146	ring finger protein 146	64970	0.12
chr1_178102702_178103151	0.18	RASAL2	RAS protein activator like 2	39650	0.22
chr1_199660662_199660904	0.17	ENSG00000263805	.	76375	0.12
chr7_102531454_102531734	0.17	LRRC17	leucine rich repeat containing 17	21844	0.16
chr2_192135580_192135731	0.17	MYO1B	myosin IB	5956	0.29
chr8_13081961_13082497	0.17	DLC1	deleted in liver cancer 1	51826	0.15
chr4_14171315_14171588	0.17	ENSG00000252092	.	511200	0.0
chr1_68112079_68112321	0.17	ENSG00000242482	.	10612	0.23
chr8_99224065_99224216	0.17	ENSG00000252558	.	19599	0.2
chr20_10286775_10287859	0.17	ENSG00000211588	.	55561	0.13
chr4_71997510_71997784	0.17	SLC4A4	solute carrier family 4 (sodium bicarbonate cotransporter), member 4	55356	0.16
chr11_95995991_95996601	0.17	ENSG00000266192	.	78306	0.1
chr7_74603766_74604170	0.16	GTF2IRD2B	GTF2I repeat domain containing 2B	47064	0.15
chr3_30537171_30537700	0.16	TGFBR2	transforming growth factor, beta receptor II (70/80kDa)	110559	0.07
chr3_42104128_42104299	0.16	TRAK1	trafficking protein, kinesin binding 1	28349	0.22
chr10_104913387_104913649	0.16	NT5C2	5'-nucleotidase, cytosolic II	134	0.97
chr3_138581340_138581807	0.16	PIK3CB	phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta	27793	0.2
chr15_77707876_77708432	0.16	PEAK1	pseudopodium-enriched atypical kinase 1	4288	0.26
chr14_73881929_73882217	0.16	NUMB	numb homolog (Drosophila)	5294	0.21
chr14_68608308_68608459	0.16	ENSG00000244677	.	8242	0.23
chr11_9774706_9775022	0.16	SBF2-AS1	SBF2 antisense RNA 1	4975	0.2
chr17_70973648_70973899	0.16	SLC39A11	solute carrier family 39, member 11	15299	0.27
chr3_17794774_17794953	0.16	TBC1D5	TBC1 domain family, member 5	10719	0.3
chr15_51602118_51602364	0.16	CYP19A1	cytochrome P450, family 19, subfamily A, polypeptide 1	8448	0.17
chr3_123668814_123668965	0.15	CCDC14	coiled-coil domain containing 14	467	0.84
chr4_141158577_141158955	0.15	SCOC	short coiled-coil protein	19674	0.2
chr1_9952782_9953028	0.15	CTNNBIP1	catenin, beta interacting protein 1	390	0.81
chr5_111304224_111304663	0.15	NREP-AS1	NREP antisense RNA 1	706	0.74
chr4_12124809_12125078	0.15	ENSG00000266669	.	109878	0.08
chr6_144355824_144356097	0.15	PLAGL1	pleiomorphic adenoma gene-like 1	26419	0.21
chr1_155732961_155733524	0.15	DAP3	death associated protein 3	26439	0.13
chr12_25920871_25921133	0.15	ENSG00000222950	.	11501	0.28
chr10_99115891_99116310	0.15	FRAT2	frequently rearranged in advanced T-cell lymphomas 2	21642	0.1
chr3_43807500_43807651	0.15	ABHD5	abhydrolase domain containing 5	54376	0.15
chr5_52109798_52109949	0.15	CTD-2288O8.1		26013	0.17
chr3_159886438_159886589	0.15	IL12A-AS1	IL12A antisense RNA 1	38366	0.15
chr2_74810778_74811272	0.15	LOXL3	lysyl oxidase-like 3	28208	0.08
chr2_131095295_131095532	0.15	IMP4	IMP4, U3 small nucleolar ribonucleoprotein, homolog (yeast)	4385	0.17
chr5_114919475_114919626	0.15	AC010226.4		18204	0.15
chr1_155618391_155618704	0.15	YY1AP1	YY1 associated protein 1	27915	0.11
chr9_94048455_94048658	0.14	AUH	AU RNA binding protein/enoyl-CoA hydratase	75621	0.12
chr2_192251959_192252110	0.14	MYO1B	myosin IB	4826	0.27
chr7_36205351_36205624	0.14	EEPD1	endonuclease/exonuclease/phosphatase family domain containing 1	12610	0.22
chr1_10182603_10182825	0.14	UBE4B	ubiquitination factor E4B	614	0.74
chr12_109057635_109057786	0.14	ENSG00000238457	.	4514	0.16
chr22_39688804_39689038	0.14	RP3-333H23.8		72	0.95
chr3_148917359_148917687	0.14	CP	ceruloplasmin (ferroxidase)	9604	0.22
chr6_16681395_16681795	0.14	RP1-151F17.1		79774	0.1
chr2_20644033_20644184	0.14	RHOB	ras homolog family member B	2727	0.28
chr17_13268235_13268519	0.14	ENSG00000266115	.	135268	0.05
chr12_66590752_66591050	0.14	IRAK3	interleukin-1 receptor-associated kinase 3	7864	0.16
chr5_136900207_136900561	0.14	ENSG00000221612	.	31241	0.19
chr1_203517854_203518108	0.14	OPTC	opticin	52883	0.13
chr8_59506824_59506976	0.14	SDCBP	syndecan binding protein (syntenin)	29325	0.19
chr12_32655690_32655927	0.14	FGD4	FYVE, RhoGEF and PH domain containing 4	657	0.77
chr3_171549465_171549722	0.14	TMEM212	transmembrane protein 212	11546	0.18
chr1_214568255_214568406	0.14	RP11-176D17.3		37372	0.19
chr6_56778927_56779078	0.14	ENSG00000200224	.	31526	0.16
chr17_60953332_60953660	0.14	MARCH10	membrane-associated ring finger (C3HC4) 10, E3 ubiquitin protein ligase	67791	0.11
chr6_114290051_114291212	0.14	RP3-399L15.3		234	0.87
chr7_92242355_92242506	0.14	FAM133B	family with sequence similarity 133, member B	22722	0.2
chr3_179134884_179135173	0.14	GNB4	guanine nucleotide binding protein (G protein), beta polypeptide 4	714	0.64
chr9_33321157_33321399	0.14	NFX1	nuclear transcription factor, X-box binding 1	30735	0.12
chr10_77229212_77229699	0.14	RP11-399K21.10		38109	0.16
chr16_50286306_50286457	0.14	ADCY7	adenylate cyclase 7	6333	0.22
chr11_61738752_61739315	0.14	AP003733.1	Uncharacterized protein; cDNA FLJ36460 fis, clone THYMU2014801	3580	0.16
chr3_138841521_138841672	0.13	MRPS22	mitochondrial ribosomal protein S22	12350	0.24
chr7_98737042_98737396	0.13	SMURF1	SMAD specific E3 ubiquitin protein ligase 1	4423	0.27
chr6_129988972_129989261	0.13	ARHGAP18	Rho GTPase activating protein 18	42254	0.19
chr2_161887841_161887992	0.13	TANK	TRAF family member-associated NFKB activator	105503	0.07
chr4_118055843_118055994	0.13	TRAM1L1	translocation associated membrane protein 1-like 1	49182	0.2
chr1_110364191_110364827	0.13	EPS8L3	EPS8-like 3	57860	0.08
chr4_7925984_7926135	0.13	AC097381.1		14669	0.19
chr21_27307663_27307857	0.13	ENSG00000233783	.	1134	0.52
chr1_98552609_98552760	0.13	ENSG00000225206	.	40957	0.22
chr10_79002677_79003016	0.13	RP11-328K22.1		70853	0.11
chr4_74600301_74600499	0.13	IL8	interleukin 8	5823	0.26
chr6_106247000_106247228	0.13	ENSG00000200198	.	105134	0.08
chr1_221099074_221099301	0.13	HLX	H2.0-like homeobox	44603	0.15
chr3_135570414_135570565	0.13	ENSG00000253004	.	51867	0.17
chr22_24869928_24870164	0.13	UPB1	ureidopropionase, beta	6840	0.16
chr10_65281872_65282748	0.13	REEP3	receptor accessory protein 3	1187	0.58
chr10_13981760_13981911	0.13	FRMD4A	FERM domain containing 4A	32534	0.19
chr2_11837137_11837372	0.13	AC106875.1		15667	0.12
chr6_107644259_107644527	0.13	PDSS2	prenyl (decaprenyl) diphosphate synthase, subunit 2	111030	0.06
chr2_208101022_208101173	0.13	AC007879.5		17879	0.2
chr12_79814559_79814710	0.13	ENSG00000221788	.	1597	0.42
chr6_131318738_131318889	0.13	EPB41L2	erythrocyte membrane protein band 4.1-like 2	3094	0.39
chr9_108051533_108051684	0.13	SLC44A1	solute carrier family 44 (choline transporter), member 1	44705	0.19
chr4_81146676_81146827	0.13	PRDM8	PR domain containing 8	28093	0.18
chr9_33819892_33820555	0.13	RP11-133O22.6		1430	0.28
chr12_78482113_78482264	0.13	RP11-136F16.1		3329	0.34
chr2_111828955_111829320	0.13	AC096670.3		42625	0.17
chr9_115321849_115322000	0.13	C9orf147	chromosome 9 open reading frame 147	72440	0.1
chr15_48894741_48894892	0.13	FBN1	fibrillin 1	43102	0.18
chr1_52024489_52024927	0.13	OSBPL9	oxysterol binding protein-like 9	18143	0.15
chr1_183851022_183851347	0.13	COLGALT2	collagen beta(1-O)galactosyltransferase 2	64568	0.12
chr13_80510337_80510488	0.13	SPRY2	sprouty homolog 2 (Drosophila)	403382	0.01
chr16_74499506_74499657	0.12	ENSG00000207525	.	1695	0.33
chr5_122461018_122461169	0.12	AC106786.1		35099	0.14
chr1_11238617_11238768	0.12	ENSG00000271794	.	9022	0.12
chr7_72618452_72618603	0.12	NCF1B	neutrophil cytosolic factor 1B pseudogene	16084	0.17
chr2_65065663_65065834	0.12	ENSG00000199964	.	4457	0.21
chr13_97769047_97769198	0.12	ENSG00000238522	.	59489	0.14
chr10_63734512_63734894	0.12	ENSG00000221272	.	47926	0.17
chr9_111396920_111397071	0.12	ACTL7B	actin-like 7B	222244	0.02
chr11_65259042_65259542	0.12	SCYL1	SCY1-like 1 (S. cerevisiae)	33256	0.08
chr3_112817241_112817392	0.12	ENSG00000238593	.	5944	0.21
chr6_154730400_154730551	0.12	CNKSR3	CNKSR family member 3	21154	0.25
chrX_19593273_19593424	0.12	MAP3K15	mitogen-activated protein kinase kinase kinase 15	59969	0.14
chr12_52182216_52182367	0.12	AC068987.1	HCG1997999; cDNA FLJ33996 fis, clone DFNES2008881	21498	0.2
chr3_128914264_128914631	0.12	CNBP	CCHC-type zinc finger, nucleic acid binding protein	11682	0.14
chr10_74498015_74498488	0.12	ENSG00000266719	.	17464	0.16
chr3_57198236_57199040	0.12	IL17RD	interleukin 17 receptor D	765	0.66
chr18_46460191_46460800	0.12	SMAD7	SMAD family member 7	14380	0.24
chr14_69516631_69516869	0.12	ACTN1-AS1	ACTN1 antisense RNA 1	69992	0.1
chr21_27298260_27298560	0.12	ENSG00000233783	.	7963	0.22
chr15_57052440_57052789	0.12	ZNF280D	zinc finger protein 280D	26330	0.25
chr2_36757574_36758239	0.12	RP11-78I14.1		17031	0.17
chr1_235053615_235054079	0.12	ENSG00000239690	.	13914	0.26
chr11_87156993_87157144	0.12	ENSG00000223015	.	160607	0.04
chr5_88851937_88852088	0.12	MEF2C-AS1	MEF2C antisense RNA 1	137388	0.05
chr15_70995885_70996036	0.12	UACA	uveal autoantigen with coiled-coil domains and ankyrin repeats	346	0.92
chr16_82104529_82104680	0.12	HSD17B2	hydroxysteroid (17-beta) dehydrogenase 2	2722	0.25
chr1_143991136_143991416	0.12	SRGAP2B	SLIT-ROBO Rho GTPase activating protein 2B	75034	0.1
chr15_62465219_62465370	0.12	C2CD4B	C2 calcium-dependent domain containing 4B	7812	0.23
chr5_149318448_149318662	0.12	ENSG00000200334	.	1139	0.42
chr6_130004534_130005262	0.12	ARHGAP18	Rho GTPase activating protein 18	26472	0.23
chr3_137762283_137762711	0.12	DZIP1L	DAZ interacting zinc finger protein 1-like	23985	0.17
chr17_36433052_36433525	0.12	RP11-1407O15.2	TBC1 domain family member 3	11447	0.15
chr3_8493806_8493957	0.12	LMCD1-AS1	LMCD1 antisense RNA 1 (head to head)	49403	0.14
chr18_22878825_22879093	0.12	CTD-2006O16.2		3131	0.37
chr15_66910964_66911559	0.12	RP11-321F6.1	HCG2003567; Uncharacterized protein	36733	0.12
chr11_12188353_12189067	0.12	MICAL2	microtubule associated monooxygenase, calponin and LIM domain containing 2	5007	0.29
chr10_127836908_127837102	0.12	ENSG00000222740	.	2854	0.38
chr10_95574063_95574214	0.12	LGI1	leucine-rich, glioma inactivated 1	56460	0.13
chr8_25771009_25771433	0.12	EBF2	early B-cell factor 2	25789	0.27
chr4_110622784_110623524	0.12	CASP6	caspase 6, apoptosis-related cysteine peptidase	851	0.59
chr11_73990200_73990857	0.12	ENSG00000206913	.	26931	0.14
chr4_146725571_146725722	0.12	RP11-181K12.2		28624	0.18
chr3_169491635_169492650	0.11	MYNN	myoneurin	89	0.93
chr2_109860627_109860778	0.11	ENSG00000265965	.	69379	0.12
chr16_72997806_72997957	0.11	ENSG00000221799	.	20875	0.21
chr3_159554251_159554402	0.11	SCHIP1	schwannomin interacting protein 1	3324	0.23
chr9_95300201_95300387	0.11	ECM2	extracellular matrix protein 2, female organ and adipocyte specific	1357	0.42
chr6_34982238_34982465	0.11	TCP11	t-complex 11, testis-specific	106471	0.06
chr4_119902260_119902411	0.11	SYNPO2	synaptopodin 2	42291	0.19
chr12_50589962_50590113	0.11	LIMA1	LIM domain and actin binding 1	4593	0.13
chr6_7204654_7204805	0.11	ENSG00000201483	.	16810	0.18
chr3_156979212_156979363	0.11	ENSG00000243176	.	24662	0.21
chr2_174889480_174890119	0.11	SP3	Sp3 transcription factor	59369	0.15
chr2_74803113_74803707	0.11	LOXL3	lysyl oxidase-like 3	20593	0.09
chr7_91655297_91655448	0.11	AKAP9	A kinase (PRKA) anchor protein 9	44080	0.16
chr20_9072914_9073065	0.11	PLCB4	phospholipase C, beta 4	23241	0.22
chr15_90224200_90224351	0.11	PLIN1	perilipin 1	1617	0.24
chr2_238001181_238001332	0.11	COPS8	COP9 signalosome subunit 8	6670	0.2
chr6_14136423_14136788	0.11	CD83	CD83 molecule	18733	0.23
chr7_107255273_107255591	0.11	ENSG00000238832	.	11624	0.14
chr5_124241911_124242195	0.11	ZNF608	zinc finger protein 608	157553	0.04
chr1_222217681_222217979	0.11	ENSG00000212094	.	31398	0.25
chr14_92864210_92864675	0.11	SLC24A4	solute carrier family 24 (sodium/potassium/calcium exchanger), member 4	10281	0.28
chr21_30166964_30167115	0.11	ENSG00000251894	.	51509	0.16
chr2_196359431_196359582	0.11	ENSG00000202206	.	19254	0.27
chr3_118894860_118895154	0.11	UPK1B	uroplakin 1B	2560	0.22
chr19_19097284_19097435	0.11	AC004447.2		4343	0.14
chr11_74160265_74160482	0.11	RP11-702H23.6		6020	0.14
chr5_93768337_93768488	0.11	KIAA0825	KIAA0825	104419	0.07
chr6_117770708_117770859	0.11	RP1-92C8.3		3905	0.17
chr9_94579747_94580327	0.11	ROR2	receptor tyrosine kinase-like orphan receptor 2	131125	0.05
chr2_197345285_197345550	0.11	HECW2	HECT, C2 and WW domain containing E3 ubiquitin protein ligase 2	111918	0.06
chr14_74533385_74533536	0.11	ALDH6A1	aldehyde dehydrogenase 6 family, member A1	2501	0.22
chr8_20233157_20233440	0.11	LZTS1	leucine zipper, putative tumor suppressor 1	71824	0.11
chr20_4879353_4879628	0.11	SLC23A2	solute carrier family 23 (ascorbic acid transporter), member 2	803	0.62
chr8_38831032_38831302	0.11	HTRA4	HtrA serine peptidase 4	516	0.5
chr13_110761676_110761827	0.11	ENSG00000265885	.	11253	0.3
chr1_58861905_58862056	0.11	OMA1	OMA1 zinc metallopeptidase	142510	0.04
chr3_149160811_149161262	0.11	TM4SF4	transmembrane 4 L six family member 4	30725	0.16
chr6_113203227_113203573	0.11	ENSG00000201386	.	89295	0.1
chr10_71232490_71232954	0.11	TSPAN15	tetraspanin 15	10902	0.21
chr11_15989853_15990583	0.11	CTD-3096P4.1		54518	0.18
chr6_138052819_138053031	0.11	ENSG00000216097	.	14840	0.24
chr9_124009409_124009697	0.11	GSN	gelsolin	20785	0.13
chr12_109245220_109245638	0.11	SSH1	slingshot protein phosphatase 1	5930	0.16

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of SOX10_SOX15

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.2	GO:0071694	sequestering of extracellular ligand from receptor(GO:0035581) sequestering of TGFbeta in extracellular matrix(GO:0035583) protein localization to extracellular region(GO:0071692) maintenance of protein location in extracellular region(GO:0071694) extracellular regulation of signal transduction(GO:1900115) extracellular negative regulation of signal transduction(GO:1900116)
0.1	0.2	GO:0060831	smoothened signaling pathway involved in dorsal/ventral neural tube patterning(GO:0060831)
0.1	0.3	GO:0060907	positive regulation of macrophage cytokine production(GO:0060907)
0.1	0.2	GO:0072201	negative regulation of mesenchymal cell proliferation(GO:0072201)
0.0	0.3	GO:0060997	dendritic spine morphogenesis(GO:0060997) regulation of dendritic spine morphogenesis(GO:0061001) dendritic spine organization(GO:0097061)
0.0	0.2	GO:0072010	renal filtration cell differentiation(GO:0061318) glomerular epithelium development(GO:0072010) glomerular visceral epithelial cell differentiation(GO:0072112) glomerular epithelial cell differentiation(GO:0072311)
0.0	0.2	GO:0071731	response to nitric oxide(GO:0071731)
0.0	0.1	GO:0032509	endosome transport via multivesicular body sorting pathway(GO:0032509)
0.0	0.2	GO:0006654	phosphatidic acid biosynthetic process(GO:0006654)
0.0	0.2	GO:0051124	synaptic growth at neuromuscular junction(GO:0051124)
0.0	0.2	GO:0048149	behavioral response to ethanol(GO:0048149)
0.0	0.1	GO:0007221	positive regulation of transcription of Notch receptor target(GO:0007221)
0.0	0.1	GO:0035385	Roundabout signaling pathway(GO:0035385)
0.0	0.1	GO:0032347	regulation of ketone biosynthetic process(GO:0010566) regulation of aldosterone metabolic process(GO:0032344) regulation of aldosterone biosynthetic process(GO:0032347)
0.0	0.1	GO:0010193	response to ozone(GO:0010193)
0.0	0.1	GO:0070050	neuron cellular homeostasis(GO:0070050)
0.0	0.2	GO:0007171	activation of transmembrane receptor protein tyrosine kinase activity(GO:0007171)
0.0	0.1	GO:0043589	skin morphogenesis(GO:0043589)
0.0	0.2	GO:0022617	extracellular matrix disassembly(GO:0022617)
0.0	0.1	GO:0060083	smooth muscle contraction involved in micturition(GO:0060083)
0.0	0.2	GO:0032430	positive regulation of phospholipase A2 activity(GO:0032430)
0.0	0.2	GO:0048625	myoblast fate commitment(GO:0048625)
0.0	0.1	GO:0048702	embryonic neurocranium morphogenesis(GO:0048702)
0.0	0.1	GO:0060750	epithelial cell proliferation involved in mammary gland duct elongation(GO:0060750)
0.0	0.1	GO:0045162	clustering of voltage-gated sodium channels(GO:0045162)
0.0	0.1	GO:0002551	mast cell chemotaxis(GO:0002551) regulation of mast cell chemotaxis(GO:0060753) positive regulation of mast cell chemotaxis(GO:0060754) mast cell migration(GO:0097531)
0.0	0.1	GO:0048845	venous blood vessel morphogenesis(GO:0048845)
0.0	0.1	GO:0009128	purine nucleoside monophosphate catabolic process(GO:0009128) ribonucleoside monophosphate catabolic process(GO:0009158) purine ribonucleoside monophosphate catabolic process(GO:0009169)
0.0	0.1	GO:0006663	platelet activating factor biosynthetic process(GO:0006663)
0.0	0.1	GO:0060394	negative regulation of pathway-restricted SMAD protein phosphorylation(GO:0060394)
0.0	0.1	GO:0006703	estrogen biosynthetic process(GO:0006703)
0.0	0.1	GO:0051305	chromosome movement towards spindle pole(GO:0051305)
0.0	0.0	GO:0055098	response to low-density lipoprotein particle(GO:0055098)
0.0	0.1	GO:0002043	blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:0002043)
0.0	0.1	GO:0070874	negative regulation of glycogen metabolic process(GO:0070874)
0.0	0.0	GO:0061042	vascular wound healing(GO:0061042) regulation of vascular wound healing(GO:0061043)
0.0	0.1	GO:0001996	positive regulation of heart rate by epinephrine-norepinephrine(GO:0001996)
0.0	0.1	GO:0008215	spermine metabolic process(GO:0008215)
0.0	0.1	GO:0046504	ether lipid biosynthetic process(GO:0008611) glycerol ether biosynthetic process(GO:0046504) ether biosynthetic process(GO:1901503)
0.0	0.1	GO:0035234	ectopic germ cell programmed cell death(GO:0035234)
0.0	0.1	GO:0001547	antral ovarian follicle growth(GO:0001547)
0.0	0.1	GO:0006651	diacylglycerol biosynthetic process(GO:0006651)
0.0	0.1	GO:1903521	apoptotic process involved in mammary gland involution(GO:0060057) positive regulation of apoptotic process involved in mammary gland involution(GO:0060058) positive regulation of apoptotic process involved in morphogenesis(GO:1902339) regulation of mammary gland involution(GO:1903519) positive regulation of mammary gland involution(GO:1903521) positive regulation of apoptotic process involved in development(GO:1904747)
0.0	0.1	GO:0030579	ubiquitin-dependent SMAD protein catabolic process(GO:0030579)
0.0	0.1	GO:0019800	peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.0	0.1	GO:0014012	peripheral nervous system axon regeneration(GO:0014012)
0.0	0.2	GO:1901532	regulation of megakaryocyte differentiation(GO:0045652) regulation of hematopoietic progenitor cell differentiation(GO:1901532)
0.0	0.1	GO:0033173	calcineurin-NFAT signaling cascade(GO:0033173)
0.0	0.0	GO:0061298	retina vasculature development in camera-type eye(GO:0061298) retina vasculature morphogenesis in camera-type eye(GO:0061299)
0.0	0.1	GO:0017121	phospholipid scrambling(GO:0017121)
0.0	0.1	GO:0071318	cellular response to ATP(GO:0071318)
0.0	0.0	GO:0060242	contact inhibition(GO:0060242)
0.0	0.1	GO:0061302	smooth muscle cell-matrix adhesion(GO:0061302)
0.0	0.1	GO:0009051	pentose-phosphate shunt, oxidative branch(GO:0009051)
0.0	0.0	GO:0070427	nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070427)
0.0	0.0	GO:0002604	dendritic cell antigen processing and presentation(GO:0002468) regulation of dendritic cell antigen processing and presentation(GO:0002604)
0.0	0.0	GO:0030011	maintenance of cell polarity(GO:0030011)
0.0	0.3	GO:0045600	positive regulation of fat cell differentiation(GO:0045600)
0.0	0.0	GO:0071502	cellular response to temperature stimulus(GO:0071502)
0.0	0.0	GO:0002540	arachidonic acid metabolite production involved in inflammatory response(GO:0002538) leukotriene production involved in inflammatory response(GO:0002540)
0.0	0.0	GO:0060437	lung growth(GO:0060437)
0.0	0.1	GO:0050872	white fat cell differentiation(GO:0050872)
0.0	0.1	GO:0051014	actin filament severing(GO:0051014)
0.0	0.1	GO:0006991	response to sterol depletion(GO:0006991)
0.0	0.1	GO:0031340	positive regulation of vesicle fusion(GO:0031340)
0.0	0.1	GO:0072383	plus-end-directed vesicle transport along microtubule(GO:0072383) plus-end-directed organelle transport along microtubule(GO:0072386)
0.0	0.1	GO:0008228	opsonization(GO:0008228)
0.0	0.0	GO:0031665	negative regulation of lipopolysaccharide-mediated signaling pathway(GO:0031665)
0.0	0.1	GO:0048245	eosinophil chemotaxis(GO:0048245) eosinophil migration(GO:0072677)
0.0	0.1	GO:0006927	obsolete transformed cell apoptotic process(GO:0006927)
0.0	0.1	GO:0045662	negative regulation of myoblast differentiation(GO:0045662)
0.0	0.1	GO:0007185	transmembrane receptor protein tyrosine phosphatase signaling pathway(GO:0007185)
0.0	0.1	GO:0033630	positive regulation of cell adhesion mediated by integrin(GO:0033630)
0.0	0.0	GO:0032048	phosphatidylglycerol biosynthetic process(GO:0006655) cardiolipin metabolic process(GO:0032048) cardiolipin biosynthetic process(GO:0032049) phosphatidylglycerol metabolic process(GO:0046471)
0.0	0.0	GO:0006824	cobalt ion transport(GO:0006824)
0.0	0.1	GO:0051769	nitric-oxide synthase biosynthetic process(GO:0051767) regulation of nitric-oxide synthase biosynthetic process(GO:0051769) positive regulation of nitric-oxide synthase biosynthetic process(GO:0051770)
0.0	0.1	GO:0060638	mesenchymal-epithelial cell signaling(GO:0060638)
0.0	0.0	GO:0010757	negative regulation of plasminogen activation(GO:0010757)
0.0	0.1	GO:0030091	protein repair(GO:0030091)
0.0	0.1	GO:2000095	regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000095)
0.0	0.3	GO:0006195	purine nucleotide catabolic process(GO:0006195)
0.0	0.1	GO:0032467	positive regulation of cytokinesis(GO:0032467)
0.0	0.1	GO:0006108	malate metabolic process(GO:0006108)
0.0	0.1	GO:0006572	tyrosine catabolic process(GO:0006572)
0.0	0.0	GO:0019859	pyrimidine nucleobase catabolic process(GO:0006208) thymine catabolic process(GO:0006210) thymine metabolic process(GO:0019859) nucleobase catabolic process(GO:0046113)
0.0	0.0	GO:0046121	deoxyribonucleoside catabolic process(GO:0046121)
0.0	0.1	GO:0009396	folic acid-containing compound biosynthetic process(GO:0009396)
0.0	0.0	GO:0005981	regulation of glycogen catabolic process(GO:0005981)
0.0	0.0	GO:0032288	myelin assembly(GO:0032288)
0.0	0.0	GO:0021670	lateral ventricle development(GO:0021670)
0.0	0.0	GO:0070672	response to interleukin-15(GO:0070672)
0.0	0.0	GO:0001845	phagolysosome assembly(GO:0001845) phagosome maturation(GO:0090382)
0.0	0.0	GO:0070172	positive regulation of tooth mineralization(GO:0070172)
0.0	0.0	GO:0006931	substrate-dependent cell migration, cell attachment to substrate(GO:0006931)
0.0	0.1	GO:0008655	pyrimidine-containing compound salvage(GO:0008655) pyrimidine nucleoside salvage(GO:0043097)
0.0	0.1	GO:0006527	arginine catabolic process(GO:0006527)
0.0	0.0	GO:0072526	pyridine-containing compound catabolic process(GO:0072526)
0.0	0.0	GO:0045657	positive regulation of monocyte differentiation(GO:0045657)
0.0	0.0	GO:1901889	negative regulation of focal adhesion assembly(GO:0051895) negative regulation of cell junction assembly(GO:1901889) negative regulation of adherens junction organization(GO:1903392)
0.0	0.1	GO:0033137	negative regulation of peptidyl-serine phosphorylation(GO:0033137)
0.0	0.1	GO:0032780	negative regulation of ATPase activity(GO:0032780)
0.0	0.0	GO:0051771	negative regulation of nitric-oxide synthase biosynthetic process(GO:0051771)
0.0	0.1	GO:0019852	L-ascorbic acid metabolic process(GO:0019852)
0.0	0.1	GO:0046487	glyoxylate metabolic process(GO:0046487)
0.0	0.1	GO:0006930	substrate-dependent cell migration, cell extension(GO:0006930)
0.0	0.1	GO:0033962	cytoplasmic mRNA processing body assembly(GO:0033962)
0.0	0.1	GO:0015840	urea transport(GO:0015840)
0.0	0.0	GO:0046485	ether lipid metabolic process(GO:0046485)
0.0	0.0	GO:0034638	phosphatidylcholine catabolic process(GO:0034638)
0.0	0.1	GO:0090162	establishment of epithelial cell polarity(GO:0090162)
0.0	0.1	GO:0090023	positive regulation of neutrophil chemotaxis(GO:0090023) positive regulation of neutrophil migration(GO:1902624)
0.0	0.1	GO:0006590	thyroid hormone generation(GO:0006590)
0.0	0.0	GO:0060528	secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development(GO:0060528)
0.0	0.1	GO:0090136	epithelial cell-cell adhesion(GO:0090136)
0.0	0.1	GO:0043306	positive regulation of mast cell activation involved in immune response(GO:0033008) positive regulation of leukocyte degranulation(GO:0043302) positive regulation of mast cell degranulation(GO:0043306)
0.0	0.0	GO:0010842	retina layer formation(GO:0010842)
0.0	0.0	GO:0016103	diterpenoid catabolic process(GO:0016103) terpenoid catabolic process(GO:0016115) retinoic acid catabolic process(GO:0034653)
0.0	0.1	GO:0036296	response to increased oxygen levels(GO:0036296) response to hyperoxia(GO:0055093)
0.0	0.1	GO:0097035	regulation of membrane lipid distribution(GO:0097035)
0.0	0.0	GO:0071681	response to indole-3-methanol(GO:0071680) cellular response to indole-3-methanol(GO:0071681)
0.0	0.1	GO:0006048	UDP-N-acetylglucosamine biosynthetic process(GO:0006048)
0.0	0.1	GO:0015871	choline transport(GO:0015871)
0.0	0.0	GO:0033147	negative regulation of intracellular estrogen receptor signaling pathway(GO:0033147)
0.0	0.1	GO:0019369	arachidonic acid metabolic process(GO:0019369)
0.0	0.0	GO:2000542	negative regulation of gastrulation(GO:2000542)
0.0	0.1	GO:0015889	cobalamin transport(GO:0015889)
0.0	0.1	GO:0031641	regulation of myelination(GO:0031641)
0.0	0.1	GO:0048821	erythrocyte development(GO:0048821) myeloid cell development(GO:0061515)
0.0	0.1	GO:0030321	transepithelial chloride transport(GO:0030321)
0.0	0.1	GO:0002138	retinoic acid biosynthetic process(GO:0002138) diterpenoid biosynthetic process(GO:0016102)
0.0	0.1	GO:0046855	phosphorylated carbohydrate dephosphorylation(GO:0046838) inositol phosphate dephosphorylation(GO:0046855)
0.0	0.1	GO:0016266	O-glycan processing(GO:0016266)
0.0	0.1	GO:0048853	forebrain morphogenesis(GO:0048853)
0.0	0.1	GO:0007016	cytoskeletal anchoring at plasma membrane(GO:0007016)
0.0	0.0	GO:0050774	negative regulation of dendrite morphogenesis(GO:0050774)
0.0	0.1	GO:0040019	positive regulation of embryonic development(GO:0040019)
0.0	0.1	GO:0045647	negative regulation of erythrocyte differentiation(GO:0045647)
0.0	0.0	GO:0007500	mesodermal cell fate determination(GO:0007500)
0.0	0.0	GO:0045163	clustering of voltage-gated potassium channels(GO:0045163)
0.0	0.0	GO:0009448	gamma-aminobutyric acid metabolic process(GO:0009448)
0.0	0.1	GO:0019695	choline metabolic process(GO:0019695)
0.0	0.1	GO:0046835	carbohydrate phosphorylation(GO:0046835)
0.0	0.3	GO:0010811	positive regulation of cell-substrate adhesion(GO:0010811)
0.0	0.0	GO:0032959	inositol trisphosphate biosynthetic process(GO:0032959)
0.0	0.0	GO:0060431	primary lung bud formation(GO:0060431)
0.0	0.0	GO:0002430	complement receptor mediated signaling pathway(GO:0002430)
0.0	0.0	GO:0016576	histone dephosphorylation(GO:0016576)
0.0	0.1	GO:0046426	negative regulation of JAK-STAT cascade(GO:0046426) negative regulation of STAT cascade(GO:1904893)
0.0	0.1	GO:0019363	pyridine nucleotide biosynthetic process(GO:0019363)
0.0	0.1	GO:0006206	pyrimidine nucleobase metabolic process(GO:0006206)
0.0	0.1	GO:0034755	iron ion transmembrane transport(GO:0034755)
0.0	0.1	GO:0035329	hippo signaling(GO:0035329)
0.0	0.0	GO:0046512	diol biosynthetic process(GO:0034312) sphingosine biosynthetic process(GO:0046512)
0.0	0.0	GO:0019919	peptidyl-arginine methylation, to asymmetrical-dimethyl arginine(GO:0019919)
0.0	0.0	GO:0015793	glycerol transport(GO:0015793)
0.0	0.0	GO:0002023	reduction of food intake in response to dietary excess(GO:0002023)
0.0	0.0	GO:0002283	neutrophil activation involved in immune response(GO:0002283) neutrophil degranulation(GO:0043312)
0.0	0.1	GO:0060259	regulation of feeding behavior(GO:0060259)
0.0	0.0	GO:0002689	negative regulation of leukocyte chemotaxis(GO:0002689)
0.0	0.0	GO:0045747	positive regulation of Notch signaling pathway(GO:0045747)
0.0	0.0	GO:0048631	regulation of skeletal muscle tissue growth(GO:0048631)
0.0	0.1	GO:0009629	response to gravity(GO:0009629)
0.0	0.0	GO:0006391	transcription initiation from mitochondrial promoter(GO:0006391)
0.0	0.1	GO:0010886	positive regulation of cholesterol storage(GO:0010886)
0.0	0.2	GO:0018149	peptide cross-linking(GO:0018149)
0.0	0.1	GO:0048712	negative regulation of astrocyte differentiation(GO:0048712)
0.0	0.0	GO:0016093	polyprenol metabolic process(GO:0016093) dolichol metabolic process(GO:0019348)
0.0	0.0	GO:0046882	negative regulation of follicle-stimulating hormone secretion(GO:0046882)
0.0	0.1	GO:0002566	somatic diversification of immune receptors via somatic mutation(GO:0002566) somatic hypermutation of immunoglobulin genes(GO:0016446)
0.0	0.0	GO:0000492	small nucleolar ribonucleoprotein complex assembly(GO:0000491) box C/D snoRNP assembly(GO:0000492)
0.0	0.0	GO:0002328	pro-B cell differentiation(GO:0002328)
0.0	0.0	GO:0055089	fatty acid homeostasis(GO:0055089)
0.0	0.0	GO:0001714	endodermal cell fate commitment(GO:0001711) endodermal cell fate specification(GO:0001714) endodermal cell differentiation(GO:0035987) regulation of endodermal cell fate specification(GO:0042663) regulation of endodermal cell differentiation(GO:1903224)
0.0	0.0	GO:0046501	protoporphyrinogen IX metabolic process(GO:0046501)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.2	GO:0043259	laminin-10 complex(GO:0043259)
0.0	0.2	GO:0016342	catenin complex(GO:0016342)
0.0	0.3	GO:0005614	interstitial matrix(GO:0005614)
0.0	0.1	GO:0032449	CBM complex(GO:0032449)
0.0	0.1	GO:0005589	collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.0	0.1	GO:0030056	hemidesmosome(GO:0030056)
0.0	0.1	GO:0071664	catenin-TCF7L2 complex(GO:0071664)
0.0	0.1	GO:0005862	muscle thin filament tropomyosin(GO:0005862)
0.0	0.1	GO:0033268	node of Ranvier(GO:0033268)
0.0	0.2	GO:0031092	platelet alpha granule membrane(GO:0031092)
0.0	0.1	GO:0030934	anchoring collagen complex(GO:0030934)
0.0	0.2	GO:0098642	network-forming collagen trimer(GO:0098642) collagen network(GO:0098645)
0.0	0.0	GO:0098651	basement membrane collagen trimer(GO:0098651)
0.0	0.1	GO:0044298	neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.0	0.1	GO:0030128	AP-2 adaptor complex(GO:0030122) clathrin coat of endocytic vesicle(GO:0030128)
0.0	0.1	GO:0005828	kinetochore microtubule(GO:0005828)
0.0	0.1	GO:0017146	NMDA selective glutamate receptor complex(GO:0017146)
0.0	0.1	GO:0016327	apicolateral plasma membrane(GO:0016327)
0.0	0.1	GO:0035253	ciliary rootlet(GO:0035253)
0.0	0.2	GO:0030315	T-tubule(GO:0030315)
0.0	0.1	GO:0001527	microfibril(GO:0001527)
0.0	0.1	GO:0042405	nuclear inclusion body(GO:0042405)
0.0	0.1	GO:0030312	external encapsulating structure(GO:0030312)
0.0	0.0	GO:0045254	pyruvate dehydrogenase complex(GO:0045254)
0.0	0.5	GO:0005884	actin filament(GO:0005884)
0.0	0.1	GO:0030127	COPII vesicle coat(GO:0030127)
0.0	0.1	GO:0043256	laminin complex(GO:0043256)
0.0	0.1	GO:0043020	NADPH oxidase complex(GO:0043020)
0.0	0.1	GO:0071437	invadopodium(GO:0071437)
0.0	0.1	GO:0000145	exocyst(GO:0000145)
0.0	0.1	GO:0030877	beta-catenin destruction complex(GO:0030877)
0.0	0.0	GO:0043625	delta DNA polymerase complex(GO:0043625)
0.0	0.0	GO:0005593	FACIT collagen trimer(GO:0005593)
0.0	0.0	GO:0000137	Golgi cis cisterna(GO:0000137)
0.0	0.2	GO:0005811	lipid particle(GO:0005811)
0.0	0.1	GO:0031143	pseudopodium(GO:0031143)
0.0	0.1	GO:0031232	extrinsic component of external side of plasma membrane(GO:0031232)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.4	GO:0051371	muscle alpha-actinin binding(GO:0051371)
0.1	0.2	GO:0001159	RNA polymerase II core promoter proximal region sequence-specific DNA binding(GO:0000978) core promoter proximal region sequence-specific DNA binding(GO:0000987) core promoter proximal region DNA binding(GO:0001159)
0.0	0.2	GO:0005010	insulin-like growth factor-activated receptor activity(GO:0005010)
0.0	0.3	GO:0008253	5'-nucleotidase activity(GO:0008253)
0.0	0.1	GO:0005006	epidermal growth factor-activated receptor activity(GO:0005006)
0.0	0.2	GO:0051637	obsolete Gram-positive bacterial cell surface binding(GO:0051637)
0.0	0.2	GO:0004470	malic enzyme activity(GO:0004470)
0.0	0.3	GO:0004908	interleukin-1 receptor activity(GO:0004908)
0.0	0.1	GO:0070052	collagen V binding(GO:0070052)
0.0	0.1	GO:0004720	protein-lysine 6-oxidase activity(GO:0004720)
0.0	0.1	GO:0032450	maltose alpha-glucosidase activity(GO:0032450)
0.0	0.1	GO:0045545	syndecan binding(GO:0045545)
0.0	0.1	GO:0045236	CXCR chemokine receptor binding(GO:0045236)
0.0	0.1	GO:0015204	urea transmembrane transporter activity(GO:0015204)
0.0	0.1	GO:0016724	ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.0	0.1	GO:0004117	calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117)
0.0	0.1	GO:0016509	long-chain-3-hydroxyacyl-CoA dehydrogenase activity(GO:0016509)
0.0	0.1	GO:0004687	myosin light chain kinase activity(GO:0004687)
0.0	0.1	GO:0004321	fatty-acyl-CoA synthase activity(GO:0004321)
0.0	0.1	GO:0015016	[heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
0.0	0.1	GO:0033130	acetylcholine receptor binding(GO:0033130)
0.0	0.1	GO:0010314	phosphatidylinositol-5-phosphate binding(GO:0010314)
0.0	0.2	GO:0017166	vinculin binding(GO:0017166)
0.0	0.2	GO:0045294	alpha-catenin binding(GO:0045294)
0.0	0.1	GO:0004461	lactose synthase activity(GO:0004461)
0.0	0.1	GO:0042805	actinin binding(GO:0042805)
0.0	0.1	GO:0048027	mRNA 5'-UTR binding(GO:0048027)
0.0	0.1	GO:0070696	transmembrane receptor protein serine/threonine kinase binding(GO:0070696)
0.0	0.3	GO:0005523	tropomyosin binding(GO:0005523)
0.0	0.1	GO:0017128	phospholipid scramblase activity(GO:0017128)
0.0	0.1	GO:0003680	AT DNA binding(GO:0003680)
0.0	0.1	GO:0005172	vascular endothelial growth factor receptor binding(GO:0005172)
0.0	0.1	GO:0032052	bile acid binding(GO:0032052)
0.0	0.1	GO:0004800	thyroxine 5'-deiodinase activity(GO:0004800)
0.0	0.1	GO:0033743	peptide-methionine (R)-S-oxide reductase activity(GO:0033743)
0.0	0.1	GO:0005017	platelet-derived growth factor-activated receptor activity(GO:0005017)
0.0	0.1	GO:0030297	transmembrane receptor protein tyrosine kinase activator activity(GO:0030297)
0.0	0.1	GO:0042808	obsolete neuronal Cdc2-like kinase binding(GO:0042808)
0.0	0.2	GO:0003810	protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.0	0.1	GO:0034056	estrogen response element binding(GO:0034056)
0.0	0.1	GO:0005173	stem cell factor receptor binding(GO:0005173)
0.0	0.3	GO:0008395	steroid hydroxylase activity(GO:0008395)
0.0	0.1	GO:0004082	bisphosphoglycerate mutase activity(GO:0004082) bisphosphoglycerate 2-phosphatase activity(GO:0004083) phosphoglycerate mutase activity(GO:0004619)
0.0	0.1	GO:0004849	uridine kinase activity(GO:0004849)
0.0	0.1	GO:0016421	CoA carboxylase activity(GO:0016421)
0.0	0.1	GO:0070290	N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.0	0.1	GO:0004982	N-formyl peptide receptor activity(GO:0004982)
0.0	0.1	GO:0017159	pantetheine hydrolase activity(GO:0017159)
0.0	0.1	GO:0047184	1-acylglycerophosphocholine O-acyltransferase activity(GO:0047184)
0.0	0.1	GO:0004616	phosphogluconate dehydrogenase (decarboxylating) activity(GO:0004616)
0.0	0.2	GO:0019864	IgG binding(GO:0019864)
0.0	0.0	GO:0070097	delta-catenin binding(GO:0070097)
0.0	0.1	GO:0001875	lipopolysaccharide receptor activity(GO:0001875)
0.0	0.1	GO:0004597	peptide-aspartate beta-dioxygenase activity(GO:0004597)
0.0	0.0	GO:0004515	nicotinamide-nucleotide adenylyltransferase activity(GO:0000309) nicotinate-nucleotide adenylyltransferase activity(GO:0004515)
0.0	0.1	GO:0030274	LIM domain binding(GO:0030274)
0.0	0.0	GO:0002162	dystroglycan binding(GO:0002162)
0.0	0.0	GO:0008475	procollagen-lysine 5-dioxygenase activity(GO:0008475)
0.0	0.1	GO:0005078	MAP-kinase scaffold activity(GO:0005078)
0.0	0.0	GO:0016623	oxidoreductase activity, acting on the aldehyde or oxo group of donors, oxygen as acceptor(GO:0016623)
0.0	0.1	GO:0030492	hemoglobin binding(GO:0030492)
0.0	0.1	GO:0047035	testosterone dehydrogenase (NAD+) activity(GO:0047035)
0.0	0.1	GO:0004300	enoyl-CoA hydratase activity(GO:0004300)
0.0	0.1	GO:0004523	RNA-DNA hybrid ribonuclease activity(GO:0004523)
0.0	0.1	GO:0008046	axon guidance receptor activity(GO:0008046)
0.0	0.2	GO:0004622	lysophospholipase activity(GO:0004622)
0.0	0.2	GO:0035035	histone acetyltransferase binding(GO:0035035)
0.0	0.0	GO:0070644	vitamin D response element binding(GO:0070644)
0.0	0.0	GO:0016802	adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.0	0.0	GO:0042577	lipid phosphatase activity(GO:0042577)
0.0	0.1	GO:0048185	activin binding(GO:0048185)
0.0	0.2	GO:0004012	phospholipid-translocating ATPase activity(GO:0004012)
0.0	0.1	GO:0016175	superoxide-generating NADPH oxidase activity(GO:0016175)
0.0	0.1	GO:0004791	thioredoxin-disulfide reductase activity(GO:0004791)
0.0	0.1	GO:0005534	galactose binding(GO:0005534)
0.0	0.1	GO:0001968	fibronectin binding(GO:0001968)
0.0	0.1	GO:0046790	virion binding(GO:0046790)
0.0	0.1	GO:0050998	nitric-oxide synthase binding(GO:0050998)
0.0	0.1	GO:0042285	UDP-xylosyltransferase activity(GO:0035252) xylosyltransferase activity(GO:0042285)
0.0	0.1	GO:0048407	platelet-derived growth factor binding(GO:0048407)
0.0	0.1	GO:0015556	C4-dicarboxylate transmembrane transporter activity(GO:0015556)
0.0	0.1	GO:0017112	Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0	0.0	GO:0005250	A-type (transient outward) potassium channel activity(GO:0005250)
0.0	0.1	GO:0008179	adenylate cyclase binding(GO:0008179)
0.0	0.0	GO:0008113	peptide-methionine (S)-S-oxide reductase activity(GO:0008113)
0.0	0.0	GO:0008898	S-adenosylmethionine-homocysteine S-methyltransferase activity(GO:0008898)
0.0	0.0	GO:0016886	ligase activity, forming phosphoric ester bonds(GO:0016886)
0.0	0.0	GO:0016715	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen(GO:0016715)
0.0	0.1	GO:0005536	glucose binding(GO:0005536)
0.0	0.4	GO:0005518	collagen binding(GO:0005518)
0.0	0.0	GO:0004111	creatine kinase activity(GO:0004111)
0.0	0.1	GO:0016813	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
0.0	0.0	GO:0004965	G-protein coupled GABA receptor activity(GO:0004965)
0.0	0.1	GO:0070008	serine-type exopeptidase activity(GO:0070008)
0.0	0.0	GO:0005350	pyrimidine nucleobase transmembrane transporter activity(GO:0005350)
0.0	0.1	GO:0000339	RNA cap binding(GO:0000339)
0.0	0.1	GO:0004859	phospholipase inhibitor activity(GO:0004859)
0.0	0.0	GO:0051636	obsolete Gram-negative bacterial cell surface binding(GO:0051636)
0.0	0.0	GO:0008510	sodium:bicarbonate symporter activity(GO:0008510)
0.0	0.0	GO:0033265	cholinesterase activity(GO:0004104) choline binding(GO:0033265)
0.0	0.0	GO:0005432	calcium:sodium antiporter activity(GO:0005432)
0.0	0.0	GO:0004875	complement receptor activity(GO:0004875)
0.0	0.0	GO:0016909	JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.0	0.1	GO:0003993	acid phosphatase activity(GO:0003993)
0.0	0.0	GO:0005030	neurotrophin receptor activity(GO:0005030)
0.0	0.1	GO:0045296	cadherin binding(GO:0045296)
0.0	0.0	GO:0050544	arachidonic acid binding(GO:0050544)
0.0	0.1	GO:0034235	GPI anchor binding(GO:0034235)
0.0	0.0	GO:0034186	apolipoprotein A-I binding(GO:0034186)
0.0	0.0	GO:0008332	low voltage-gated calcium channel activity(GO:0008332)
0.0	0.0	GO:0003987	acetate-CoA ligase activity(GO:0003987)
0.0	0.1	GO:0022821	potassium ion antiporter activity(GO:0022821)
0.0	0.5	GO:0008009	chemokine activity(GO:0008009)
0.0	0.2	GO:0005242	inward rectifier potassium channel activity(GO:0005242)
0.0	0.1	GO:0030506	ankyrin binding(GO:0030506)
0.0	0.0	GO:0043515	kinetochore binding(GO:0043515)
0.0	0.0	GO:0000293	ferric-chelate reductase activity(GO:0000293)
0.0	0.1	GO:0008504	monoamine transmembrane transporter activity(GO:0008504)

Gene overrepresentation in curated gene sets: canonical pathways category:

Total log-likelihood	Term	Description
0.1	PID IGF1 PATHWAY	IGF1 pathway
0.0	PID THROMBIN PAR4 PATHWAY	PAR4-mediated thrombin signaling events
0.2	PID IL1 PATHWAY	IL1-mediated signaling events
0.0	PID TRAIL PATHWAY	TRAIL signaling pathway
0.0	PID A6B1 A6B4 INTEGRIN PATHWAY	a6b1 and a6b4 Integrin signaling
0.0	PID GMCSF PATHWAY	GMCSF-mediated signaling events
0.2	PID FGF PATHWAY	FGF signaling pathway
0.0	PID ECADHERIN KERATINOCYTE PATHWAY	E-cadherin signaling in keratinocytes
0.4	PID INTEGRIN A9B1 PATHWAY	Alpha9 beta1 integrin signaling events
0.3	PID ERBB NETWORK PATHWAY	ErbB receptor signaling network
0.1	PID RET PATHWAY	Signaling events regulated by Ret tyrosine kinase
0.5	NABA BASEMENT MEMBRANES	Genes encoding structural components of basement membranes
0.0	PID PDGFRA PATHWAY	PDGFR-alpha signaling pathway
0.0	SA PTEN PATHWAY	PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Total log-likelihood	Term	Description
0.1	REACTOME SIGNALING BY FGFR	Genes involved in Signaling by FGFR
0.4	REACTOME PURINE CATABOLISM	Genes involved in Purine catabolism
0.2	REACTOME ADP SIGNALLING THROUGH P2RY12	Genes involved in ADP signalling through P2Y purinoceptor 12
0.0	REACTOME BILE ACID AND BILE SALT METABOLISM	Genes involved in Bile acid and bile salt metabolism
0.5	REACTOME SMOOTH MUSCLE CONTRACTION	Genes involved in Smooth Muscle Contraction
0.6	REACTOME MYOGENESIS	Genes involved in Myogenesis
0.2	REACTOME VEGF LIGAND RECEPTOR INTERACTIONS	Genes involved in VEGF ligand-receptor interactions
0.2	REACTOME NOTCH HLH TRANSCRIPTION PATHWAY	Genes involved in Notch-HLH transcription pathway
0.2	REACTOME ENDOGENOUS STEROLS	Genes involved in Endogenous sterols
0.2	REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE	Genes involved in Synthesis of PIPs at the late endosome membrane
0.0	REACTOME INFLUENZA VIRAL RNA TRANSCRIPTION AND REPLICATION	Genes involved in Influenza Viral RNA Transcription and Replication
0.3	REACTOME PYRIMIDINE METABOLISM	Genes involved in Pyrimidine metabolism
0.0	REACTOME TRIGLYCERIDE BIOSYNTHESIS	Genes involved in Triglyceride Biosynthesis
0.2	REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS	Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.2	REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS	Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.1	REACTOME SIGNAL ATTENUATION	Genes involved in Signal attenuation
0.0	REACTOME ALPHA LINOLENIC ACID ALA METABOLISM	Genes involved in alpha-linolenic acid (ALA) metabolism
0.0	REACTOME DOWNSTREAM SIGNAL TRANSDUCTION	Genes involved in Downstream signal transduction
0.1	REACTOME TIE2 SIGNALING	Genes involved in Tie2 Signaling