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ENCODE: H3K4me1 ChIP-Seq of primary human cells
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Results for SOX14

Z-value: 1.22

Motif logo

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Transcription factors associated with SOX14

Gene Symbol Gene ID Gene Info
SOX14
ENSG00000168875.1 SRY-box transcription factor 14

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE Gene Distance Association probability Pearson corr. coef. P-value Plot
chr3_137486884_137487092SOX1434090.379818-0.599.7e-02Click!
chr3_137490047_137490281SOX1465850.3249790.589.8e-02Click!
chr3_137490658_137490996SOX1472480.320540-0.571.1e-01Click!
chr3_137483109_137483260SOX143950.920583-0.481.9e-01Click!
chr3_137489858_137490009SOX1463540.326771-0.432.4e-01Click!

Activity of the SOX14 motif across conditions

Conditions sorted by the z-value of the SOX14 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE) Target Score Top associated gene Gene Info Distance of CRE to TSS CRE/Gene association probability
chr4_103967796_103967947 0.46 SLC9B2
 solute carrier family 9, subfamily B (NHA2, cation proton antiporter 2), member 2
 11228
 0.21
chr10_43648011_43648162 0.39 CSGALNACT2
 chondroitin sulfate N-acetylgalactosaminyltransferase 2
 14152
 0.22
chr19_14486268_14486999 0.38 CD97
 CD97 molecule
 5335
 0.16
chr5_145155108_145155259 0.37 PRELID2
 PRELI domain containing 2
 59665
 0.15
chr2_3225421_3225572 0.36 TSSC1-IT1
 TSSC1 intronic transcript 1 (non-protein coding)
 79740
 0.1
chr20_4795714_4796665 0.36 RASSF2
 Ras association (RalGDS/AF-6) domain family member 2
 420
 0.85
chr2_145219103_145219318 0.35 ZEB2
 zinc finger E-box binding homeobox 2
 31073
 0.22
chr4_79583519_79583729 0.34 ENSG00000238816
 .
 22370
 0.19
chr3_134516445_134516596 0.33 EPHB1
 EPH receptor B1
 1537
 0.41
chr10_97552518_97552961 0.33 ENTPD1
 ectonucleoside triphosphate diphosphohydrolase 1
 37025
 0.15
chr1_36173339_36173885 0.32 ENSG00000239859
 .
 1737
 0.31
chr16_56999551_56999979 0.31 CETP
 cholesteryl ester transfer protein, plasma
 3746
 0.14
chr3_148674000_148674298 0.31 RP11-680B3.2
3750
 0.26
chrX_77173850_77174555 0.31 ATP7A
 ATPase, Cu++ transporting, alpha polypeptide
 8003
 0.16
chr10_44312151_44312815 0.31 ZNF32
 zinc finger protein 32
 168179
 0.03
chr8_10128293_10128444 0.30 MSRA
 methionine sulfoxide reductase A
 30677
 0.22
chr1_61598374_61598525 0.28 RP4-802A10.1
8044
 0.25
chr1_66837902_66838308 0.28 PDE4B
 phosphodiesterase 4B, cAMP-specific
 18040
 0.28
chr9_131007648_131008173 0.28 ENSG00000264823
 .
 601
 0.42
chr15_70196429_70196590 0.27 ENSG00000215958
 .
 118666
 0.06
chr14_22926253_22926566 0.26 TRDD3
 T cell receptor delta diversity 3
 8304
 0.11
chr5_17441932_17442083 0.26 ENSG00000201715
 .
 96282
 0.09
chr11_47949983_47950362 0.26 PTPRJ
 protein tyrosine phosphatase, receptor type, J
 51941
 0.12
chr10_64378374_64378669 0.26 ZNF365
 zinc finger protein 365
 25012
 0.22
chr10_7991050_7991201 0.26 GATA3
 GATA binding protein 3
 105531
 0.07
chr11_1145070_1145742 0.26 MUC5AC
 mucin 5AC, oligomeric mucus/gel-forming
 6174
 0.2
chr18_46242484_46242870 0.25 RP11-426J5.2
27887
 0.2
chr19_17610867_17611300 0.25 SLC27A1
 solute carrier family 27 (fatty acid transporter), member 1
 92
 0.93
chr19_50009932_50010143 0.25 FCGRT
 Fc fragment of IgG, receptor, transporter, alpha
 5499
 0.06
chr3_11494368_11494519 0.25 ATG7
 autophagy related 7
 88310
 0.09
chr5_43674374_43674666 0.25 NNT
 nicotinamide nucleotide transhydrogenase
 29061
 0.2
chr5_156955806_156956039 0.25 ADAM19
 ADAM metallopeptidase domain 19
 26092
 0.14
chr3_66330359_66330510 0.25 ENSG00000206759
 .
 13210
 0.22
chr10_30789869_30790276 0.25 ENSG00000239744
 .
 54761
 0.13
chr8_21542340_21542522 0.25 GFRA2
 GDNF family receptor alpha 2
 103404
 0.07
chr1_201574377_201574631 0.24 AC096677.1
 Uncharacterized protein ENSP00000471857
 17509
 0.16
chr1_54830860_54831046 0.24 SSBP3
 single stranded DNA binding protein 3
 40224
 0.15
chr11_48057199_48057485 0.24 AC103828.1
19935
 0.19
chrX_19705406_19705851 0.24 SH3KBP1
 SH3-domain kinase binding protein 1
 16512
 0.28
chr4_54633852_54634003 0.23 LNX1
 ligand of numb-protein X 1, E3 ubiquitin protein ligase
 66355
 0.12
chr2_161235850_161236019 0.23 ENSG00000252465
 .
 17545
 0.2
chr5_64485748_64485899 0.23 ENSG00000207439
 .
 66627
 0.14
chr3_132956077_132956228 0.23 RP11-402L6.1
19740
 0.23
chr2_64328647_64328937 0.23 AC074289.1
41581
 0.16
chr8_98272161_98272312 0.23 TSPYL5
 TSPY-like 5
 17940
 0.25
chr10_31986594_31986822 0.23 ENSG00000222412
 .
 58356
 0.16
chr3_107697056_107697238 0.23 CD47
 CD47 molecule
 80061
 0.11
chr5_94926047_94926198 0.23 GPR150
 G protein-coupled receptor 150
 29660
 0.13
chr1_117036571_117036783 0.22 ENSG00000200547
 .
 41519
 0.12
chr19_51670246_51671430 0.22 SIGLEC17P
 sialic acid binding Ig-like lectin 17, pseudogene
 184
 0.89
chr2_121360012_121360163 0.22 ENSG00000201006
 .
 48762
 0.18
chr1_97899901_97900052 0.22 DPYD-IT1
 DPYD intronic transcript 1 (non-protein coding)
 14279
 0.31
chr11_67057839_67058573 0.22 ANKRD13D
 ankyrin repeat domain 13 family, member D
 1333
 0.3
chr8_61454233_61454384 0.22 RP11-91I20.4
11287
 0.22
chr7_47547067_47547313 0.22 TNS3
 tensin 3
 26307
 0.26
chr14_79073358_79073509 0.22 NRXN3
 neurexin 3
 7842
 0.22
chr1_183001256_183001465 0.22 LAMC1
 laminin, gamma 1 (formerly LAMB2)
 8765
 0.21
chr4_55808155_55808468 0.22 ENSG00000264332
 .
 68788
 0.11
chr13_100027297_100027717 0.21 ENSG00000207719
 .
 19122
 0.2
chr18_53868353_53868679 0.21 ENSG00000201816
 .
 121691
 0.07
chr11_128607706_128608101 0.21 FLI1
 Fli-1 proto-oncogene, ETS transcription factor
 26782
 0.17
chr3_129311849_129312381 0.21 ENSG00000239437
 .
 1923
 0.28
chr6_20484087_20484358 0.21 ENSG00000201683
 .
 16184
 0.16
chr18_22811436_22811645 0.21 ZNF521
 zinc finger protein 521
 46
 0.99
chr2_102049705_102049856 0.21 RFX8
 RFX family member 8, lacking RFX DNA binding domain
 40957
 0.16
chr2_38010215_38010366 0.21 CDC42EP3
 CDC42 effector protein (Rho GTPase binding) 3
 44679
 0.19
chr13_32059321_32059637 0.21 RXFP2
 relaxin/insulin-like family peptide receptor 2
 254195
 0.02
chrX_153947159_153947493 0.20 GAB3
 GRB2-associated binding protein 3
 32006
 0.1
chr8_130602358_130602703 0.20 ENSG00000266387
 .
 92617
 0.06
chr8_142424232_142425134 0.20 PTP4A3
 protein tyrosine phosphatase type IVA, member 3
 7324
 0.13
chr6_47492501_47492652 0.20 ENSG00000199762
 .
 35773
 0.16
chr6_5985144_5985295 0.20 NRN1
 neuritin 1
 21981
 0.22
chr17_27071776_27071993 0.20 TRAF4
 TNF receptor-associated factor 4
 781
 0.27
chr1_59622775_59622926 0.20 FGGY
 FGGY carbohydrate kinase domain containing
 139460
 0.05
chr6_3869542_3869744 0.20 FAM50B
 family with sequence similarity 50, member B
 20021
 0.19
chr5_126146602_126147018 0.20 LMNB1
 lamin B1
 33929
 0.19
chr4_111987974_111988125 0.20 ENSG00000215961
 .
 206246
 0.03
chr22_18903424_18903575 0.20 DGCR6
 DiGeorge syndrome critical region gene 6
 9633
 0.17
chr17_27072175_27072438 0.20 TRAF4
 TNF receptor-associated factor 4
 1203
 0.16
chr15_29106368_29106519 0.20 GOLGA6L7P
 golgin A6 family-like 7, pseudogene
 12715
 0.18
chr16_48595927_48596078 0.20 RP11-44I10.3
2430
 0.3
chr1_204446570_204446721 0.20 PIK3C2B
 phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta
 10171
 0.19
chr13_32622361_32622649 0.20 FRY
 furry homolog (Drosophila)
 12496
 0.23
chr8_132854804_132854955 0.20 EFR3A
 EFR3 homolog A (S. cerevisiae)
 61456
 0.16
chr3_16340065_16340275 0.20 RP11-415F23.2
15776
 0.16
chr9_38084332_38084615 0.20 SHB
 Src homology 2 domain containing adaptor protein B
 15263
 0.24
chr8_105350987_105351434 0.20 DCSTAMP
 dendrocyte expressed seven transmembrane protein
 844
 0.68
chr2_42425739_42426081 0.20 AC083949.1
28469
 0.19
chr3_187989530_187989681 0.20 LPP
 LIM domain containing preferred translocation partner in lipoma
 31953
 0.22
chr1_64553029_64553180 0.19 ENSG00000200508
 .
 20691
 0.17
chr6_167383774_167384203 0.19 RNASET2
 ribonuclease T2
 13316
 0.13
chrX_135836171_135836490 0.19 ARHGEF6
 Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6
 13172
 0.18
chr5_157940155_157940453 0.19 CTD-2363C16.1
469710
 0.01
chr18_46585815_46585966 0.19 ENSG00000263849
 .
 9752
 0.19
chr10_63554784_63554935 0.19 ARID5B
 AT rich interactive domain 5B (MRF1-like)
 106200
 0.07
chr19_13320112_13320432 0.19 CACNA1A
 calcium channel, voltage-dependent, P/Q type, alpha 1A subunit
 47942
 0.08
chr8_61925745_61925971 0.19 CLVS1
 clavesin 1
 43859
 0.2
chr1_65522143_65522294 0.19 ENSG00000265996
 .
 1307
 0.39
chr17_9160012_9160446 0.19 RP11-85B7.4
26262
 0.21
chr10_75563756_75563907 0.19 NDST2
 N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 2
 729
 0.41
chr18_65598176_65598327 0.19 DSEL
 dermatan sulfate epimerase-like
 414034
 0.01
chr12_120120626_120120777 0.19 PRKAB1
 protein kinase, AMP-activated, beta 1 non-catalytic subunit
 10652
 0.16
chr11_121963982_121964133 0.19 ENSG00000207971
 .
 6495
 0.17
chr8_27468856_27469025 0.19 CLU
 clusterin
 8
 0.98
chr11_48030445_48030685 0.18 AC103828.1
6842
 0.22
chr8_102505453_102505604 0.18 GRHL2
 grainyhead-like 2 (Drosophila)
 542
 0.6
chr1_240397636_240397787 0.18 FMN2
 formin 2
 10849
 0.24
chr1_206755327_206755741 0.18 RASSF5
 Ras association (RalGDS/AF-6) domain family member 5
 25041
 0.13
chr19_1651787_1652144 0.18 TCF3
 transcription factor 3
 361
 0.81
chr2_107576982_107577133 0.18 ST6GAL2
 ST6 beta-galactosamide alpha-2,6-sialyltranferase 2
 73493
 0.12
chr10_79287048_79287199 0.18 ENSG00000199592
 .
 59684
 0.14
chr9_120481193_120481344 0.18 ENSG00000201444
 .
 10888
 0.2
chr17_17753098_17753798 0.18 TOM1L2
 target of myb1-like 2 (chicken)
 12646
 0.14
chr7_27964371_27964522 0.18 ENSG00000265382
 .
 44340
 0.16
chr11_48088655_48089020 0.18 ENSG00000263693
 .
 29497
 0.17
chr5_61880973_61881321 0.18 LRRC70
 leucine rich repeat containing 70
 6445
 0.23
chr13_75343971_75344251 0.18 ENSG00000206812
 .
 339613
 0.01
chr10_105152344_105152495 0.18 ENSG00000221767
 .
 1739
 0.21
chr14_69551433_69551584 0.18 ENSG00000206768
 .
 59162
 0.11
chr11_111658887_111659109 0.18 PPP2R1B
 protein phosphatase 2, regulatory subunit A, beta
 21847
 0.14
chr7_37429018_37429454 0.17 ENSG00000200113
 .
 29995
 0.15
chr1_56602778_56602929 0.17 PIGQP1
 phosphatidylinositol glycan anchor biosynthesis, class Q pseudogene 1
 197900
 0.03
chr2_69054034_69054428 0.17 AC097495.2
4945
 0.22
chrX_109937306_109937457 0.17 CHRDL1
 chordin-like 1
 101612
 0.08
chr10_6237578_6237796 0.17 RP11-414H17.5
6969
 0.16
chr1_28222979_28223130 0.17 RPA2
 replication protein A2, 32kDa
 542
 0.67
chr8_85094524_85094675 0.17 RALYL
 RALY RNA binding protein-like
 423
 0.91
chr2_8534562_8534786 0.17 AC011747.7
281222
 0.01
chr9_79207509_79207915 0.17 ENSG00000241781
 .
 20981
 0.22
chr11_47989764_47989999 0.17 PTPRJ
 protein tyrosine phosphatase, receptor type, J
 12232
 0.21
chr9_100199219_100199370 0.17 TDRD7
 tudor domain containing 7
 24918
 0.19
chr19_19562771_19562932 0.17 GATAD2A
 GATA zinc finger domain containing 2A
 5070
 0.15
chr16_72821877_72822476 0.17 ENSG00000265573
 .
 504
 0.64
chr3_112391920_112392214 0.17 CCDC80
 coiled-coil domain containing 80
 31920
 0.2
chr7_45233024_45233175 0.17 RAMP3
 receptor (G protein-coupled) activity modifying protein 3
 35671
 0.15
chr21_46471417_46471568 0.17 AP001579.1
 Uncharacterized protein
 21435
 0.14
chr11_124708975_124709188 0.17 ENSG00000215942
 .
 3962
 0.14
chr1_183086575_183086726 0.17 LAMC1
 laminin, gamma 1 (formerly LAMB2)
 20971
 0.18
chr6_84992412_84992563 0.17 KIAA1009
 KIAA1009
 55134
 0.18
chr5_14144482_14144849 0.17 TRIO
 trio Rho guanine nucleotide exchange factor
 836
 0.77
chr6_72129760_72130197 0.17 ENSG00000207827
 .
 16654
 0.22
chr12_93797733_93797884 0.17 NUDT4
 nudix (nucleoside diphosphate linked moiety X)-type motif 4
 25378
 0.13
chr2_145269557_145269741 0.17 ZEB2
 zinc finger E-box binding homeobox 2
 5466
 0.26
chr7_75955987_75956138 0.17 HSPB1
 heat shock 27kDa protein 1
 23168
 0.13
chr2_64969896_64970153 0.17 ENSG00000253082
 .
 33214
 0.17
chr9_80635533_80635684 0.17 GNAQ
 guanine nucleotide binding protein (G protein), q polypeptide
 9912
 0.31
chr17_56232433_56232668 0.17 OR4D1
 olfactory receptor, family 4, subfamily D, member 1
 56
 0.97
chr3_47844781_47845806 0.17 DHX30
 DEAH (Asp-Glu-Ala-His) box helicase 30
 638
 0.69
chr17_6657101_6657320 0.17 XAF1
 XIAP associated factor 1
 1674
 0.3
chr11_96024786_96024937 0.17 ENSG00000266192
 .
 49741
 0.14
chr13_30389980_30390131 0.17 UBL3
 ubiquitin-like 3
 34766
 0.23
chr1_10182603_10182825 0.16 UBE4B
 ubiquitination factor E4B
 614
 0.74
chrX_19620903_19621086 0.16 SH3KBP1
 SH3-domain kinase binding protein 1
 67486
 0.13
chr3_194277464_194277768 0.16 ENSG00000252053
 .
 23304
 0.12
chr6_49397963_49398114 0.16 MUT
 methylmalonyl CoA mutase
 32866
 0.16
chr10_114863343_114863771 0.16 TCF7L2
 transcription factor 7-like 2 (T-cell specific, HMG-box)
 40122
 0.21
chr20_47339217_47339820 0.16 ENSG00000251876
 .
 16467
 0.27
chr4_113263286_113263437 0.16 ALPK1
 alpha-kinase 1
 44825
 0.13
chr13_78406581_78406732 0.16 EDNRB
 endothelin receptor type B
 86289
 0.08
chr6_56390814_56390965 0.16 DST
 dystonin
 52101
 0.16
chrX_67905613_67905964 0.16 STARD8
 StAR-related lipid transfer (START) domain containing 8
 7705
 0.31
chr5_72634397_72634548 0.16 FOXD1
 forkhead box D1
 109880
 0.06
chr12_57947057_57947208 0.16 KIF5A
 kinesin family member 5A
 3305
 0.1
chr10_120873283_120874145 0.16 FAM45A
 family with sequence similarity 45, member A
 10085
 0.14
chr19_10097648_10097799 0.16 CTD-2553C6.1
8950
 0.11
chr12_11864478_11864709 0.16 ETV6
 ets variant 6
 40842
 0.2
chr9_136710943_136711094 0.16 SARDH
 sarcosine dehydrogenase
 105941
 0.06
chr8_37132456_37132991 0.16 RP11-150O12.6
241816
 0.02
chr6_107979051_107979415 0.16 SCML4
 sex comb on midleg-like 4 (Drosophila)
 74366
 0.11
chr6_90963667_90963818 0.16 BACH2
 BTB and CNC homology 1, basic leucine zipper transcription factor 2
 42719
 0.18
chr11_19799330_19799633 0.16 NAV2
 neuron navigator 2
 9
 0.98
chr15_88415316_88415597 0.16 NTRK3
 neurotrophic tyrosine kinase, receptor, type 3
 60865
 0.16
chr7_155251375_155251945 0.16 EN2
 engrailed homeobox 2
 836
 0.63
chrX_65244659_65244810 0.16 ENSG00000207939
 .
 6022
 0.22
chrX_77423682_77423833 0.16 TAF9B
 TAF9B RNA polymerase II, TATA box binding protein (TBP)-associated factor, 31kDa
 28554
 0.22
chr21_35135967_35136118 0.16 ITSN1
 intersectin 1 (SH3 domain protein)
 28696
 0.19
chr7_128716222_128716373 0.16 ENSG00000238733
 .
 14712
 0.16
chrX_77193735_77193886 0.16 ATP7A
 ATPase, Cu++ transporting, alpha polypeptide
 27611
 0.14
chr1_109261913_109262064 0.16 FNDC7
 fibronectin type III domain containing 7
 3045
 0.21
chr5_34718601_34718752 0.16 RAI14
 retinoic acid induced 14
 31012
 0.19
chr5_88175476_88175627 0.16 MEF2C
 myocyte enhancer factor 2C
 1757
 0.41
chr4_103433017_103433168 0.16 NFKB1
 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
 8560
 0.21
chr7_141998755_141998906 0.16 PRSS3P3
 protease, serine, 3 pseudogene 3
 9221
 0.22
chrX_153401312_153401677 0.16 OPN1LW
 opsin 1 (cone pigments), long-wave-sensitive
 8204
 0.13
chr6_26479269_26479651 0.16 BTN2A1
 butyrophilin, subfamily 2, member A1
 14005
 0.12
chr12_65044536_65044708 0.16 RP11-338E21.3
4177
 0.16
chr12_114371307_114371458 0.15 RP11-780K2.1
1008
 0.65
chr2_209133854_209134145 0.15 PIKFYVE
 phosphoinositide kinase, FYVE finger containing
 2912
 0.19
chr5_115844005_115844156 0.15 SEMA6A
 sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A
 28044
 0.22
chr2_48559099_48559360 0.15 ENSG00000251889
 .
 8736
 0.22
chrX_117646925_117647156 0.15 DOCK11
 dedicator of cytokinesis 11
 17168
 0.23
chr11_12150023_12150174 0.15 MICAL2
 microtubule associated monooxygenase, calponin and LIM domain containing 2
 7076
 0.29
chr10_29975293_29975444 0.15 ENSG00000222092
 .
 25476
 0.2
chr18_56554770_56555263 0.15 ZNF532
 zinc finger protein 532
 22230
 0.17
chr3_168599289_168599440 0.15 MECOM
 MDS1 and EVI1 complex locus
 246458
 0.02
chr10_81134576_81134901 0.15 RP11-342M3.5
7346
 0.21
chr9_92040656_92041457 0.15 SEMA4D
 sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D
 7308
 0.26
chr5_130728834_130729229 0.15 CDC42SE2
 CDC42 small effector 2
 7732
 0.31
chr4_143260601_143260752 0.15 INPP4B
 inositol polyphosphate-4-phosphatase, type II, 105kDa
 33579
 0.26
chrX_10911310_10911578 0.15 MID1
 midline 1 (Opitz/BBB syndrome)
 59671
 0.16

Histogram of CRE-TSS distances for CREs targeted by :

Histogram of

Rank distribution of CRE target scores:

Histogram of target CRE score.

Distribution of target CREs across different genomic regions:

Weighted Piechart of Weighted Piechart of Weighted Piechart of

Network of associatons between targets according to the STRING database.

First level regulatory network of SOX14

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.6 GO:0033152 immunoglobulin V(D)J recombination(GO:0033152)
0.1 0.2 GO:0046471 phosphatidylglycerol biosynthetic process(GO:0006655) cardiolipin metabolic process(GO:0032048) cardiolipin biosynthetic process(GO:0032049) phosphatidylglycerol metabolic process(GO:0046471)
0.1 0.2 GO:0060242 contact inhibition(GO:0060242)
0.1 0.2 GO:0007343 egg activation(GO:0007343)
0.1 0.2 GO:0070050 neuron cellular homeostasis(GO:0070050)
0.1 0.3 GO:0051788 response to misfolded protein(GO:0051788)
0.1 0.2 GO:0021859 pyramidal neuron differentiation(GO:0021859) pyramidal neuron development(GO:0021860)
0.0 0.1 GO:0019276 UDP-N-acetylgalactosamine metabolic process(GO:0019276)
0.0 0.1 GO:0042996 regulation of Golgi to plasma membrane protein transport(GO:0042996)
0.0 0.2 GO:0021631 optic nerve morphogenesis(GO:0021631)
0.0 0.1 GO:0051305 chromosome movement towards spindle pole(GO:0051305)
0.0 0.2 GO:0070570 regulation of axon regeneration(GO:0048679) regulation of neuron projection regeneration(GO:0070570)
0.0 0.1 GO:1900115 sequestering of extracellular ligand from receptor(GO:0035581) sequestering of TGFbeta in extracellular matrix(GO:0035583) protein localization to extracellular region(GO:0071692) maintenance of protein location in extracellular region(GO:0071694) extracellular regulation of signal transduction(GO:1900115) extracellular negative regulation of signal transduction(GO:1900116)
0.0 0.1 GO:0010957 negative regulation of calcidiol 1-monooxygenase activity(GO:0010956) negative regulation of vitamin D biosynthetic process(GO:0010957) negative regulation of vitamin metabolic process(GO:0046137)
0.0 0.1 GO:0051497 negative regulation of stress fiber assembly(GO:0051497)
0.0 0.1 GO:0035405 histone-threonine phosphorylation(GO:0035405)
0.0 0.2 GO:0007185 transmembrane receptor protein tyrosine phosphatase signaling pathway(GO:0007185)
0.0 0.0 GO:0060028 convergent extension involved in axis elongation(GO:0060028)
0.0 0.1 GO:0010572 positive regulation of platelet activation(GO:0010572)
0.0 0.1 GO:0045003 DNA recombinase assembly(GO:0000730) double-strand break repair via synthesis-dependent strand annealing(GO:0045003)
0.0 0.1 GO:0010447 response to acidic pH(GO:0010447)
0.0 0.1 GO:0090073 positive regulation of protein homodimerization activity(GO:0090073)
0.0 0.1 GO:0048934 peripheral nervous system neuron differentiation(GO:0048934)
0.0 0.1 GO:0009221 pyrimidine deoxyribonucleotide biosynthetic process(GO:0009221)
0.0 0.2 GO:1901532 regulation of megakaryocyte differentiation(GO:0045652) regulation of hematopoietic progenitor cell differentiation(GO:1901532)
0.0 0.1 GO:0048859 formation of anatomical boundary(GO:0048859)
0.0 0.1 GO:0007442 hindgut morphogenesis(GO:0007442) hindgut development(GO:0061525)
0.0 0.1 GO:0071480 cellular response to gamma radiation(GO:0071480)
0.0 0.1 GO:0008356 asymmetric cell division(GO:0008356)
0.0 0.1 GO:0001543 ovarian follicle rupture(GO:0001543)
0.0 0.1 GO:0009649 entrainment of circadian clock(GO:0009649)
0.0 0.0 GO:0009189 deoxyribonucleoside diphosphate biosynthetic process(GO:0009189)
0.0 0.1 GO:0045163 clustering of voltage-gated potassium channels(GO:0045163)
0.0 0.1 GO:0060054 positive regulation of epithelial cell proliferation involved in wound healing(GO:0060054)
0.0 0.1 GO:0060997 dendritic spine morphogenesis(GO:0060997) regulation of dendritic spine morphogenesis(GO:0061001) dendritic spine organization(GO:0097061)
0.0 0.1 GO:0017183 peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183)
0.0 0.0 GO:0001955 blood vessel maturation(GO:0001955)
0.0 0.1 GO:0006853 carnitine shuttle(GO:0006853) carnitine transmembrane transport(GO:1902603)
0.0 0.1 GO:0048312 intracellular distribution of mitochondria(GO:0048312)
0.0 0.0 GO:0009138 pyrimidine nucleoside diphosphate metabolic process(GO:0009138)
0.0 0.1 GO:2000846 corticosteroid hormone secretion(GO:0035930) regulation of steroid hormone secretion(GO:2000831) regulation of corticosteroid hormone secretion(GO:2000846)
0.0 0.1 GO:0016266 O-glycan processing(GO:0016266)
0.0 0.1 GO:0030223 neutrophil differentiation(GO:0030223)
0.0 0.1 GO:0002032 desensitization of G-protein coupled receptor protein signaling pathway by arrestin(GO:0002032)
0.0 0.1 GO:0009405 pathogenesis(GO:0009405)
0.0 0.1 GO:1901341 activation of store-operated calcium channel activity(GO:0032237) regulation of store-operated calcium channel activity(GO:1901339) positive regulation of store-operated calcium channel activity(GO:1901341)
0.0 0.1 GO:0071731 response to nitric oxide(GO:0071731)
0.0 0.1 GO:0015889 cobalamin transport(GO:0015889)
0.0 0.0 GO:0042789 mRNA transcription from RNA polymerase II promoter(GO:0042789)
0.0 0.0 GO:0002019 regulation of renal output by angiotensin(GO:0002019)
0.0 0.1 GO:0034446 substrate adhesion-dependent cell spreading(GO:0034446)
0.0 0.1 GO:0045663 positive regulation of myoblast differentiation(GO:0045663)
0.0 0.1 GO:0070208 protein heterotrimerization(GO:0070208)
0.0 0.1 GO:0003402 planar cell polarity pathway involved in axis elongation(GO:0003402)
0.0 0.0 GO:0000491 small nucleolar ribonucleoprotein complex assembly(GO:0000491) box C/D snoRNP assembly(GO:0000492)
0.0 0.0 GO:0002043 blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:0002043)
0.0 0.0 GO:0033147 negative regulation of intracellular estrogen receptor signaling pathway(GO:0033147)
0.0 0.1 GO:0031641 regulation of myelination(GO:0031641)
0.0 0.0 GO:0002326 B cell lineage commitment(GO:0002326)
0.0 0.0 GO:0043162 ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043162)
0.0 0.3 GO:0001755 neural crest cell migration(GO:0001755)
0.0 0.1 GO:0043615 astrocyte cell migration(GO:0043615)
0.0 0.0 GO:0048304 positive regulation of isotype switching to IgG isotypes(GO:0048304)
0.0 0.1 GO:0007023 post-chaperonin tubulin folding pathway(GO:0007023)
0.0 0.1 GO:0018345 protein palmitoylation(GO:0018345)
0.0 0.0 GO:0030644 cellular chloride ion homeostasis(GO:0030644) chloride ion homeostasis(GO:0055064)
0.0 0.0 GO:0051152 positive regulation of smooth muscle cell differentiation(GO:0051152)
0.0 0.1 GO:0007097 nuclear migration(GO:0007097)
0.0 0.1 GO:0046642 negative regulation of alpha-beta T cell proliferation(GO:0046642)
0.0 0.0 GO:0046877 regulation of saliva secretion(GO:0046877)
0.0 0.0 GO:0060523 prostate epithelial cord elongation(GO:0060523)
0.0 0.0 GO:0030948 negative regulation of vascular endothelial growth factor receptor signaling pathway(GO:0030948)
0.0 0.0 GO:0010766 negative regulation of sodium ion transport(GO:0010766)
0.0 0.1 GO:0008653 lipopolysaccharide metabolic process(GO:0008653)
0.0 0.0 GO:0045636 positive regulation of melanocyte differentiation(GO:0045636) positive regulation of pigment cell differentiation(GO:0050942)
0.0 0.1 GO:0007549 dosage compensation(GO:0007549)
0.0 0.0 GO:0002328 pro-B cell differentiation(GO:0002328)
0.0 0.1 GO:0032493 response to bacterial lipoprotein(GO:0032493) response to bacterial lipopeptide(GO:0070339) cellular response to bacterial lipoprotein(GO:0071220) cellular response to bacterial lipopeptide(GO:0071221)
0.0 0.1 GO:0070265 necrotic cell death(GO:0070265)
0.0 0.0 GO:0001705 ectoderm formation(GO:0001705)
0.0 0.0 GO:0030505 inorganic diphosphate transport(GO:0030505)
0.0 0.1 GO:0045359 interferon-beta biosynthetic process(GO:0045350) regulation of interferon-beta biosynthetic process(GO:0045357) positive regulation of interferon-beta biosynthetic process(GO:0045359)
0.0 0.0 GO:0032682 negative regulation of chemokine production(GO:0032682) negative regulation of chemokine biosynthetic process(GO:0045079)
0.0 0.0 GO:0072577 endothelial cell apoptotic process(GO:0072577) epithelial cell apoptotic process(GO:1904019) regulation of epithelial cell apoptotic process(GO:1904035) regulation of endothelial cell apoptotic process(GO:2000351)
0.0 0.1 GO:0044341 sodium-dependent phosphate transport(GO:0044341)
0.0 0.0 GO:0072217 negative regulation of metanephros development(GO:0072217)
0.0 0.0 GO:0030854 positive regulation of granulocyte differentiation(GO:0030854)
0.0 0.0 GO:0006189 'de novo' IMP biosynthetic process(GO:0006189)
0.0 0.1 GO:0002063 chondrocyte development(GO:0002063)
0.0 0.0 GO:0042726 flavin-containing compound metabolic process(GO:0042726)
0.0 0.1 GO:0006303 double-strand break repair via nonhomologous end joining(GO:0006303)
0.0 0.0 GO:0070498 interleukin-1-mediated signaling pathway(GO:0070498)
0.0 0.1 GO:1901797 negative regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043518) negative regulation of signal transduction by p53 class mediator(GO:1901797)
0.0 0.1 GO:0060391 positive regulation of SMAD protein import into nucleus(GO:0060391)
0.0 0.1 GO:0046487 glyoxylate metabolic process(GO:0046487)
0.0 0.0 GO:0032878 regulation of establishment or maintenance of cell polarity(GO:0032878)
0.0 0.0 GO:0048245 eosinophil chemotaxis(GO:0048245) eosinophil migration(GO:0072677)
0.0 0.1 GO:0060710 chorio-allantoic fusion(GO:0060710)
0.0 0.0 GO:0030538 embryonic genitalia morphogenesis(GO:0030538)
0.0 0.1 GO:0050775 positive regulation of dendrite morphogenesis(GO:0050775)
0.0 0.0 GO:0060737 prostate gland morphogenetic growth(GO:0060737)
0.0 0.0 GO:0006681 galactosylceramide metabolic process(GO:0006681)
0.0 0.0 GO:0051103 DNA ligation involved in DNA repair(GO:0051103)
0.0 0.0 GO:0006927 obsolete transformed cell apoptotic process(GO:0006927)
0.0 0.1 GO:1903672 positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050) positive regulation of sprouting angiogenesis(GO:1903672)
0.0 0.0 GO:0010803 regulation of tumor necrosis factor-mediated signaling pathway(GO:0010803)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0033270 paranode region of axon(GO:0033270)
0.0 0.1 GO:0033268 node of Ranvier(GO:0033268)
0.0 0.1 GO:0032444 activin responsive factor complex(GO:0032444)
0.0 0.2 GO:0034366 spherical high-density lipoprotein particle(GO:0034366)
0.0 0.2 GO:0005697 telomerase holoenzyme complex(GO:0005697)
0.0 0.1 GO:0043259 laminin-10 complex(GO:0043259)
0.0 0.1 GO:0005958 DNA-dependent protein kinase-DNA ligase 4 complex(GO:0005958)
0.0 0.1 GO:0048179 activin receptor complex(GO:0048179)
0.0 0.0 GO:0005896 interleukin-6 receptor complex(GO:0005896)
0.0 0.1 GO:0005662 DNA replication factor A complex(GO:0005662)
0.0 0.0 GO:0032809 neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.0 0.0 GO:0009331 glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.0 0.0 GO:0045323 interleukin-1 receptor complex(GO:0045323)
0.0 0.1 GO:0042582 primary lysosome(GO:0005766) azurophil granule(GO:0042582)
0.0 0.2 GO:0005844 polysome(GO:0005844)
0.0 0.0 GO:0005588 collagen type V trimer(GO:0005588)
0.0 0.1 GO:0042599 lamellar body(GO:0042599)
0.0 0.1 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.0 0.0 GO:0005900 oncostatin-M receptor complex(GO:0005900)
0.0 0.1 GO:0001527 microfibril(GO:0001527)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0031957 very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.1 0.2 GO:0070053 thrombospondin receptor activity(GO:0070053)
0.1 0.1 GO:0003829 beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity(GO:0003829)
0.0 0.2 GO:0042285 UDP-xylosyltransferase activity(GO:0035252) xylosyltransferase activity(GO:0042285)
0.0 0.1 GO:0070644 vitamin D response element binding(GO:0070644)
0.0 0.1 GO:0004677 DNA-dependent protein kinase activity(GO:0004677)
0.0 0.2 GO:0070097 delta-catenin binding(GO:0070097)
0.0 0.1 GO:0016531 copper chaperone activity(GO:0016531)
0.0 0.1 GO:0050501 hyaluronan synthase activity(GO:0050501)
0.0 0.1 GO:0000978 RNA polymerase II core promoter proximal region sequence-specific DNA binding(GO:0000978) core promoter proximal region sequence-specific DNA binding(GO:0000987) core promoter proximal region DNA binding(GO:0001159)
0.0 0.2 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.0 0.1 GO:0016309 1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
0.0 0.1 GO:0035184 histone threonine kinase activity(GO:0035184)
0.0 0.1 GO:0016416 carnitine O-palmitoyltransferase activity(GO:0004095) O-palmitoyltransferase activity(GO:0016416)
0.0 0.1 GO:0008109 N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109)
0.0 0.1 GO:0005042 netrin receptor activity(GO:0005042)
0.0 0.0 GO:0005127 ciliary neurotrophic factor receptor binding(GO:0005127)
0.0 0.0 GO:0016530 metallochaperone activity(GO:0016530)
0.0 0.0 GO:0004340 glucokinase activity(GO:0004340)
0.0 0.1 GO:0008046 axon guidance receptor activity(GO:0008046)
0.0 0.2 GO:0019864 IgG binding(GO:0019864)
0.0 0.1 GO:0016774 phosphotransferase activity, carboxyl group as acceptor(GO:0016774)
0.0 0.1 GO:0016361 activin receptor activity, type I(GO:0016361)
0.0 0.1 GO:0005315 inorganic phosphate transmembrane transporter activity(GO:0005315)
0.0 0.2 GO:0051787 misfolded protein binding(GO:0051787)
0.0 0.1 GO:0047238 glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity(GO:0047238)
0.0 0.1 GO:0047623 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.0 0.1 GO:0048020 CCR chemokine receptor binding(GO:0048020)
0.0 0.1 GO:0004465 lipoprotein lipase activity(GO:0004465)
0.0 0.1 GO:0005536 glucose binding(GO:0005536)
0.0 0.4 GO:0017022 myosin binding(GO:0017022)
0.0 0.4 GO:0045028 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.0 0.1 GO:0061659 ubiquitin-ubiquitin ligase activity(GO:0034450) ubiquitin protein ligase activity(GO:0061630) ubiquitin-like protein ligase activity(GO:0061659)
0.0 0.0 GO:0016842 amidine-lyase activity(GO:0016842)
0.0 0.1 GO:0048018 receptor agonist activity(GO:0048018)
0.0 0.1 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.0 0.1 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.0 0.0 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.0 0.0 GO:0003836 beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.0 0.1 GO:0003964 telomerase activity(GO:0003720) RNA-directed DNA polymerase activity(GO:0003964)
0.0 0.1 GO:0008113 peptide-methionine (S)-S-oxide reductase activity(GO:0008113)
0.0 0.0 GO:0042978 ornithine decarboxylase activator activity(GO:0042978)
0.0 0.1 GO:0043208 glycosphingolipid binding(GO:0043208)
0.0 0.0 GO:0004946 bombesin receptor activity(GO:0004946)
0.0 0.0 GO:0004461 lactose synthase activity(GO:0004461)
0.0 0.0 GO:0004924 oncostatin-M receptor activity(GO:0004924)
0.0 0.0 GO:0016728 ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
0.0 0.0 GO:0008607 phosphorylase kinase regulator activity(GO:0008607)
0.0 0.0 GO:0016901 oxidoreductase activity, acting on the CH-OH group of donors, quinone or similar compound as acceptor(GO:0016901)
0.0 0.1 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.0 0.1 GO:0005499 vitamin D binding(GO:0005499)
0.0 0.0 GO:0004738 pyruvate dehydrogenase activity(GO:0004738) pyruvate dehydrogenase (acetyl-transferring) activity(GO:0004739)
0.0 0.0 GO:0003909 DNA ligase activity(GO:0003909) DNA ligase (ATP) activity(GO:0003910)
0.0 0.0 GO:0016151 nickel cation binding(GO:0016151)
0.0 0.1 GO:0004075 biotin carboxylase activity(GO:0004075)
0.0 0.0 GO:0004833 tryptophan 2,3-dioxygenase activity(GO:0004833)
0.0 0.0 GO:0008241 peptidyl-dipeptidase activity(GO:0008241)
0.0 0.0 GO:0016721 superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
0.0 0.0 GO:0047756 chondroitin 4-sulfotransferase activity(GO:0047756)
0.0 0.1 GO:0004331 fructose-2,6-bisphosphate 2-phosphatase activity(GO:0004331)
0.0 0.0 GO:0004619 bisphosphoglycerate mutase activity(GO:0004082) bisphosphoglycerate 2-phosphatase activity(GO:0004083) phosphoglycerate mutase activity(GO:0004619)
0.0 0.0 GO:0004476 mannose-6-phosphate isomerase activity(GO:0004476)
0.0 0.1 GO:0004908 interleukin-1 receptor activity(GO:0004908)
0.0 0.1 GO:0008195 phosphatidate phosphatase activity(GO:0008195)
0.0 0.0 GO:0004939 beta-adrenergic receptor activity(GO:0004939)
0.0 0.1 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.0 0.1 GO:0003997 acyl-CoA oxidase activity(GO:0003997)
0.0 0.0 GO:0030284 estrogen receptor activity(GO:0030284)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 PID ALK2 PATHWAY ALK2 signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.0 0.1 REACTOME BINDING AND ENTRY OF HIV VIRION Genes involved in Binding and entry of HIV virion
0.0 0.0 REACTOME PLATELET CALCIUM HOMEOSTASIS Genes involved in Platelet calcium homeostasis
0.0 0.4 REACTOME GPVI MEDIATED ACTIVATION CASCADE Genes involved in GPVI-mediated activation cascade
0.0 0.0 REACTOME APC C CDC20 MEDIATED DEGRADATION OF MITOTIC PROTEINS Genes involved in APC/C:Cdc20 mediated degradation of mitotic proteins
0.0 0.1 REACTOME P2Y RECEPTORS Genes involved in P2Y receptors
0.0 0.1 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.0 0.2 REACTOME SYNTHESIS OF PC Genes involved in Synthesis of PC
0.0 0.1 REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR Genes involved in Trafficking and processing of endosomal TLR
0.0 0.3 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.0 0.1 REACTOME HYALURONAN METABOLISM Genes involved in Hyaluronan metabolism