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ENCODE: H3K4me1 ChIP-Seq of primary human cells
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Results for SOX17

Z-value: 1.56

Motif logo

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Transcription factors associated with SOX17

Gene Symbol Gene ID Gene Info
SOX17
ENSG00000164736.5 SRY-box transcription factor 17

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE Gene Distance Association probability Pearson corr. coef. P-value Plot
chr8_55366717_55366868SOX1737030.302189-0.818.5e-03Click!
chr8_55379558_55379709SOX1791380.261717-0.742.2e-02Click!
chr8_55367558_55367715SOX1728590.336887-0.665.3e-02Click!
chr8_55366934_55367085SOX1734860.309113-0.627.7e-02Click!
chr8_55366358_55366509SOX1740620.292759-0.627.7e-02Click!

Activity of the SOX17 motif across conditions

Conditions sorted by the z-value of the SOX17 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE) Target Score Top associated gene Gene Info Distance of CRE to TSS CRE/Gene association probability
chr4_79575534_79575744 0.39 ENSG00000238816
 .
 14385
 0.21
chr18_46270227_46270648 0.36 RP11-426J5.2
55647
 0.13
chr11_67141426_67142374 0.35 CLCF1
 cardiotrophin-like cytokine factor 1
 252
 0.81
chr20_9239531_9239912 0.35 PLCB4
 phospholipase C, beta 4
 41684
 0.21
chr12_118124324_118124475 0.35 KSR2
 kinase suppressor of ras 2
 12203
 0.3
chr13_76225766_76225917 0.34 LMO7
 LIM domain 7
 15382
 0.17
chr1_221099074_221099301 0.33 HLX
 H2.0-like homeobox
 44603
 0.15
chr11_34449252_34449782 0.32 CAT
 catalase
 10955
 0.23
chr4_114305053_114305337 0.31 ANK2
 ankyrin 2, neuronal
 10680
 0.22
chr5_90603533_90603789 0.31 ENSG00000199643
 .
 37117
 0.18
chr11_73024899_73025487 0.31 ARHGEF17
 Rho guanine nucleotide exchange factor (GEF) 17
 2583
 0.2
chr15_67055010_67055873 0.30 SMAD6
 SMAD family member 6
 51406
 0.15
chr9_91390340_91390723 0.30 ENSG00000265873
 .
 29711
 0.24
chr7_26893246_26893503 0.29 SKAP2
 src kinase associated phosphoprotein 2
 3865
 0.32
chr8_95983279_95983772 0.29 NDUFAF6
 NADH dehydrogenase (ubiquinone) complex I, assembly factor 6
 9636
 0.15
chr10_706571_706722 0.29 RP11-809C18.5
2852
 0.21
chr1_185368997_185369148 0.29 ENSG00000252407
 .
 34304
 0.19
chr10_28004089_28004350 0.27 MKX
 mohawk homeobox
 28255
 0.18
chr10_80022765_80022916 0.27 ENSG00000201393
 .
 104424
 0.08
chr10_78318665_78318816 0.26 RP11-325D15.2
2012
 0.47
chr6_82886298_82886449 0.26 ENSG00000223044
 .
 33784
 0.21
chr7_80264220_80264371 0.26 CD36
 CD36 molecule (thrombospondin receptor)
 3665
 0.37
chr2_238318033_238318184 0.26 COL6A3
 collagen, type VI, alpha 3
 4683
 0.23
chr13_28534615_28535489 0.26 CDX2
 caudal type homeobox 2
 10224
 0.14
chr5_158173853_158174004 0.26 CTD-2363C16.1
236086
 0.02
chr6_16391457_16391608 0.26 ENSG00000265642
 .
 37222
 0.21
chr11_118475244_118475483 0.25 PHLDB1
 pleckstrin homology-like domain, family B, member 1
 1792
 0.23
chr16_75278250_75278858 0.25 BCAR1
 breast cancer anti-estrogen resistance 1
 1954
 0.25
chr7_77079843_77080131 0.25 ENSG00000238453
 .
 26882
 0.19
chr10_90724518_90724791 0.25 ACTA2
 actin, alpha 2, smooth muscle, aorta
 12124
 0.15
chr3_29555706_29555931 0.24 RBMS3-AS2
 RBMS3 antisense RNA 2
 102728
 0.08
chr12_20658278_20658429 0.24 RP11-284H19.1
135157
 0.05
chr1_68048532_68048683 0.24 ENSG00000207504
 .
 41797
 0.16
chr5_93581719_93582069 0.24 FAM172A
 family with sequence similarity 172, member A
 134513
 0.05
chr12_15950766_15950967 0.24 EPS8
 epidermal growth factor receptor pathway substrate 8
 8356
 0.28
chr6_116733337_116733739 0.24 DSE
 dermatan sulfate epimerase
 41428
 0.1
chr10_4720032_4720183 0.24 AKR1E2
 aldo-keto reductase family 1, member E2
 108714
 0.07
chr2_159365928_159366227 0.23 ENSG00000251721
 .
 24635
 0.18
chr6_134299599_134299750 0.23 TBPL1
 TBP-like 1
 25312
 0.21
chr7_18794771_18794922 0.23 ENSG00000222164
 .
 53056
 0.17
chr3_177624604_177624755 0.23 ENSG00000199858
 .
 100888
 0.09
chr4_88727397_88727610 0.23 IBSP
 integrin-binding sialoprotein
 6770
 0.18
chr5_53949820_53950094 0.23 SNX18
 sorting nexin 18
 136364
 0.05
chr7_80414599_80414988 0.23 CD36
 CD36 molecule (thrombospondin receptor)
 112101
 0.07
chr1_235053615_235054079 0.23 ENSG00000239690
 .
 13914
 0.26
chr1_94761220_94761475 0.23 ARHGAP29
 Rho GTPase activating protein 29
 58158
 0.14
chr4_19776674_19776825 0.23 SLIT2
 slit homolog 2 (Drosophila)
 478134
 0.01
chr12_63292090_63292337 0.23 PPM1H
 protein phosphatase, Mg2+/Mn2+ dependent, 1H
 36604
 0.16
chr2_191706793_191706944 0.22 GLS
 glutaminase
 38685
 0.16
chr9_114721568_114721719 0.22 ENSG00000266315
 .
 27263
 0.16
chr7_80415975_80416126 0.22 CD36
 CD36 molecule (thrombospondin receptor)
 113358
 0.07
chr19_33885604_33886026 0.22 CEBPG
 CCAAT/enhancer binding protein (C/EBP), gamma
 20597
 0.19
chr17_36607297_36607925 0.22 ENSG00000260833
 .
 321
 0.87
chr15_39438573_39438724 0.22 RP11-624L4.1
27734
 0.25
chr12_102288439_102288933 0.22 DRAM1
 DNA-damage regulated autophagy modulator 1
 13406
 0.14
chr8_48435057_48435320 0.22 RP11-697N18.4
4771
 0.31
chr4_129388350_129388501 0.22 PGRMC2
 progesterone receptor membrane component 2
 178441
 0.03
chr2_69480804_69480955 0.22 ENSG00000199460
 .
 70870
 0.09
chr2_173995015_173995166 0.22 MLTK
 Mitogen-activated protein kinase kinase kinase MLT
 39743
 0.17
chr12_120130068_120130348 0.22 RP1-127H14.3
 Uncharacterized protein
 7365
 0.17
chr2_102686423_102686780 0.22 IL1R1
 interleukin 1 receptor, type I
 235
 0.95
chr9_112942282_112942517 0.22 C9orf152
 chromosome 9 open reading frame 152
 28070
 0.2
chr5_67667888_67668039 0.21 PIK3R1
 phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
 79567
 0.11
chr2_213462726_213462977 0.21 ERBB4
 v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 4
 59286
 0.16
chr8_22562900_22563666 0.21 EGR3
 early growth response 3
 12468
 0.13
chr4_41015470_41015621 0.21 APBB2
 amyloid beta (A4) precursor protein-binding, family B, member 2
 857
 0.64
chr15_39997484_39997635 0.21 RP11-37C7.3
77213
 0.08
chr4_174337071_174337307 0.21 SCRG1
 stimulator of chondrogenesis 1
 16502
 0.15
chr3_43582591_43582742 0.21 ANO10
 anoctamin 10
 14237
 0.25
chr6_152894974_152895125 0.21 RP11-133I21.2
27981
 0.2
chr3_149183835_149183986 0.21 TM4SF4
 transmembrane 4 L six family member 4
 7851
 0.22
chr9_4302715_4302866 0.21 GLIS3
 GLIS family zinc finger 3
 2874
 0.27
chr12_27519472_27519623 0.21 ARNTL2
 aryl hydrocarbon receptor nuclear translocator-like 2
 1681
 0.44
chr18_59660622_59660853 0.21 RNF152
 ring finger protein 152
 99273
 0.08
chr2_226986115_226986427 0.21 ENSG00000263363
 .
 537238
 0.0
chr15_33210698_33210849 0.21 FMN1
 formin 1
 7688
 0.22
chr7_116804373_116804524 0.21 ST7-AS2
 ST7 antisense RNA 2
 17914
 0.23
chr6_130707481_130707632 0.21 TMEM200A
 transmembrane protein 200A
 20677
 0.2
chr5_121428399_121428550 0.21 LOX
 lysyl oxidase
 14494
 0.2
chr12_11864478_11864709 0.21 ETV6
 ets variant 6
 40842
 0.2
chr3_119305313_119305668 0.21 ADPRH
 ADP-ribosylarginine hydrolase
 4578
 0.16
chr1_97718242_97718393 0.20 DPYD-AS1
 DPYD antisense RNA 1
 156838
 0.04
chr8_59870660_59870811 0.20 RP11-328K2.1
34762
 0.22
chr12_109213549_109213779 0.20 SSH1
 slingshot protein phosphatase 1
 6398
 0.16
chr22_46439284_46440015 0.20 RP6-109B7.5
9324
 0.11
chr8_25781818_25781969 0.20 EBF2
 early B-cell factor 2
 36461
 0.23
chr3_149165689_149165973 0.20 TM4SF4
 transmembrane 4 L six family member 4
 25930
 0.17
chr5_64337018_64337402 0.20 ENSG00000207439
 .
 81986
 0.11
chr8_123197757_123197908 0.20 ENSG00000238901
 .
 485698
 0.01
chr5_158428554_158428967 0.20 CTD-2363C16.2
15946
 0.22
chr10_114788206_114788458 0.20 RP11-57H14.2
76698
 0.1
chr3_90060750_90060901 0.20 ENSG00000212598
 .
 18609
 0.3
chr8_78478320_78478688 0.20 ENSG00000222334
 .
 279452
 0.02
chr4_139143123_139143274 0.20 SLC7A11
 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
 20305
 0.25
chr4_81172882_81173033 0.20 FGF5
 fibroblast growth factor 5
 14796
 0.23
chr1_150779693_150780543 0.20 CTSK
 cathepsin K
 208
 0.91
chr20_48345752_48345903 0.20 ENSG00000264946
 .
 7341
 0.19
chr12_101692527_101692678 0.20 UTP20
 UTP20, small subunit (SSU) processome component, homolog (yeast)
 18715
 0.19
chr11_14280223_14280374 0.19 RP11-21L19.1
14939
 0.24
chr5_143416527_143416678 0.19 ENSG00000239390
 .
 103842
 0.07
chr16_4001736_4001887 0.19 RP11-462G12.1
1366
 0.4
chr11_77034277_77034428 0.19 PAK1
 p21 protein (Cdc42/Rac)-activated kinase 1
 25980
 0.19
chr8_119944366_119944655 0.19 TNFRSF11B
 tumor necrosis factor receptor superfamily, member 11b
 19929
 0.23
chr1_244014136_244014917 0.19 AKT3
 v-akt murine thymoma viral oncogene homolog 3
 145
 0.97
chr3_30273256_30273457 0.19 ENSG00000199927
 .
 72671
 0.11
chr2_9106079_9106230 0.19 ENSG00000238888
 .
 12870
 0.25
chr1_178244906_178245188 0.19 RASAL2
 RAS protein activator like 2
 65559
 0.14
chr17_76385949_76386473 0.19 ENSG00000200063
 .
 9805
 0.13
chr11_32054621_32054772 0.19 RP1-17K7.2
8098
 0.17
chr7_134938605_134938973 0.19 STRA8
 stimulated by retinoic acid 8
 22058
 0.17
chr9_79207509_79207915 0.19 ENSG00000241781
 .
 20981
 0.22
chr3_112497948_112498099 0.19 ENSG00000242770
 .
 23302
 0.22
chr21_44417521_44417672 0.19 PKNOX1
 PBX/knotted 1 homeobox 1
 22845
 0.15
chr5_149530280_149530569 0.19 PDGFRB
 platelet-derived growth factor receptor, beta polypeptide
 4766
 0.17
chr5_172226180_172226429 0.19 ENSG00000206741
 .
 19207
 0.13
chr9_2085870_2086021 0.19 RP11-264I13.2
39922
 0.18
chr7_81771662_81771813 0.19 MIR1255B1
 microRNA 1255b-1
 133229
 0.05
chr9_16625723_16625874 0.19 RP11-62F24.1
124
 0.98
chr9_89213139_89213290 0.19 ENSG00000222293
 .
 175171
 0.03
chrX_39949861_39950479 0.19 BCOR
 BCL6 corepressor
 6486
 0.33
chr6_3472796_3472947 0.19 SLC22A23
 solute carrier family 22, member 23
 15615
 0.27
chr14_38020205_38020356 0.19 FOXA1
 forkhead box A1
 43959
 0.16
chr13_109597565_109597716 0.19 MYO16
 myosin XVI
 59123
 0.16
chr14_61611936_61612087 0.19 PRKCH
 protein kinase C, eta
 42266
 0.17
chr5_64493902_64494516 0.19 ENSG00000207439
 .
 75013
 0.12
chr12_102319723_102319998 0.19 RP11-512N21.3
1363
 0.4
chr12_20625127_20625278 0.19 RP11-284H19.1
102006
 0.08
chr1_240399314_240399591 0.19 FMN2
 formin 2
 9108
 0.25
chr1_22251707_22252306 0.19 HSPG2
 heparan sulfate proteoglycan 2
 11784
 0.15
chr8_59801983_59802134 0.19 ENSG00000201231
 .
 74947
 0.11
chr9_113606609_113606760 0.19 ENSG00000206923
 .
 58933
 0.13
chr7_134512008_134512159 0.19 CALD1
 caldesmon 1
 16552
 0.27
chr3_29226532_29226683 0.19 RBMS3
 RNA binding motif, single stranded interacting protein 3
 95866
 0.08
chr8_116477187_116477365 0.19 TRPS1
 trichorhinophalangeal syndrome I
 27172
 0.23
chr21_40392911_40393288 0.19 ENSG00000272015
 .
 126390
 0.05
chr11_87156993_87157144 0.19 ENSG00000223015
 .
 160607
 0.04
chr5_88831623_88831774 0.19 MEF2C-AS1
 MEF2C antisense RNA 1
 117074
 0.07
chr18_448002_448153 0.19 RP11-720L2.2
23661
 0.19
chr3_81501815_81501966 0.19 ENSG00000222389
 .
 56737
 0.18
chr8_21542340_21542522 0.19 GFRA2
 GDNF family receptor alpha 2
 103404
 0.07
chr7_84252921_84253072 0.18 ENSG00000265050
 .
 42328
 0.21
chr12_6472663_6473337 0.18 SCNN1A
 sodium channel, non-voltage-gated 1 alpha subunit
 313
 0.83
chr3_151102482_151102667 0.18 P2RY12
 purinergic receptor P2Y, G-protein coupled, 12
 26
 0.98
chr7_28064670_28064821 0.18 JAZF1
 JAZF zinc finger 1
 4327
 0.32
chr8_130655393_130655686 0.18 GSDMC
 gasdermin C
 143595
 0.04
chr8_97024655_97024806 0.18 GDF6
 growth differentiation factor 6
 148290
 0.04
chr9_137118247_137118684 0.18 ENSG00000221676
 .
 88779
 0.07
chr6_85535174_85535325 0.18 TBX18
 T-box 18
 61012
 0.16
chr2_169385393_169385803 0.18 ENSG00000265694
 .
 53855
 0.12
chr15_77518685_77518901 0.18 PEAK1
 pseudopodium-enriched atypical kinase 1
 26080
 0.24
chr12_66441049_66441200 0.18 ENSG00000251857
 .
 18877
 0.2
chr11_130348992_130349281 0.18 ADAMTS15
 ADAM metallopeptidase with thrombospondin type 1 motif, 15
 30267
 0.21
chr3_73651209_73651360 0.18 ENSG00000239119
 .
 8131
 0.21
chr4_74898801_74899032 0.18 CXCL3
 chemokine (C-X-C motif) ligand 3
 5490
 0.15
chr3_135794311_135794474 0.18 RP11-305O4.3
12363
 0.25
chr8_49439487_49439638 0.18 RP11-770E5.1
24565
 0.27
chr2_69314906_69315057 0.18 ANTXR1
 anthrax toxin receptor 1
 12246
 0.2
chr3_29931035_29931186 0.18 RBMS3-AS1
 RBMS3 antisense RNA 1
 44537
 0.21
chrX_111881069_111881367 0.18 ENSG00000200436
 .
 23667
 0.22
chr2_162963271_162963422 0.18 DPP4
 dipeptidyl-peptidase 4
 32294
 0.15
chr15_43797657_43797855 0.18 TP53BP1
 tumor protein p53 binding protein 1
 5056
 0.16
chr4_89491580_89491731 0.18 ENSG00000252322
 .
 13468
 0.16
chr18_10377014_10377165 0.18 ENSG00000239031
 .
 12908
 0.27
chr6_134084843_134084994 0.18 RP3-323P13.2
3828
 0.35
chr4_146728993_146729144 0.18 RP11-181K12.2
25202
 0.2
chr14_90389082_90389233 0.18 EFCAB11
 EF-hand calcium binding domain 11
 31710
 0.18
chr10_13981760_13981911 0.18 FRMD4A
 FERM domain containing 4A
 32534
 0.19
chr12_58924723_58924874 0.18 RP11-362K2.2
 Protein LOC100506869
 13109
 0.31
chr5_67628013_67628218 0.18 PIK3R1
 phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
 39719
 0.21
chr10_79992002_79992207 0.18 ENSG00000201393
 .
 135160
 0.05
chr7_81267105_81267256 0.18 HGF
 hepatocyte growth factor (hepapoietin A; scatter factor)
 125132
 0.06
chr1_231837911_231838062 0.18 ENSG00000222986
 .
 31605
 0.2
chr8_7251752_7252001 0.18 ZNF705G
 zinc finger protein 705G
 8796
 0.15
chr2_217180969_217181120 0.18 AC069155.1
12996
 0.17
chr1_240262420_240262571 0.18 FMN2
 formin 2
 7315
 0.26
chr8_67067455_67067606 0.18 CRH
 corticotropin releasing hormone
 23430
 0.21
chr2_189834856_189835007 0.18 COL3A1
 collagen, type III, alpha 1
 4115
 0.26
chr12_26784440_26784591 0.18 RP11-666F17.1
8213
 0.3
chr3_29329993_29330144 0.18 RBMS3-AS3
 RBMS3 antisense RNA 3
 2149
 0.36
chr7_34025958_34026171 0.18 BMPER
 BMP binding endothelial regulator
 80919
 0.11
chr6_109992699_109992850 0.18 AK9
 adenylate kinase 9
 8914
 0.23
chr7_75273876_75274027 0.18 HIP1
 huntingtin interacting protein 1
 32790
 0.16
chr12_25876644_25876795 0.18 ENSG00000222950
 .
 55784
 0.14
chr9_79075654_79076239 0.18 GCNT1
 glucosaminyl (N-acetyl) transferase 1, core 2
 1800
 0.46
chr2_189674111_189674262 0.18 DIRC1
 disrupted in renal carcinoma 1
 19355
 0.22
chr14_52192816_52192967 0.18 ENSG00000207004
 .
 2070
 0.29
chr11_3980211_3980997 0.18 STIM1
 stromal interaction molecule 1
 12031
 0.18
chr10_119215065_119215278 0.18 EMX2OS
 EMX2 opposite strand/antisense RNA
 21513
 0.22
chr17_13268235_13268519 0.18 ENSG00000266115
 .
 135268
 0.05
chr7_98705625_98705861 0.18 SMURF1
 SMAD specific E3 ubiquitin protein ligase 1
 35899
 0.17
chr5_176972744_176973255 0.18 FAM193B
 family with sequence similarity 193, member B
 6647
 0.12
chr9_15936653_15936804 0.18 CCDC171
 coiled-coil domain containing 171
 158962
 0.04
chr1_211999301_211999452 0.17 RP11-552D8.1
3812
 0.19
chr3_141163664_141163815 0.17 ZBTB38
 zinc finger and BTB domain containing 38
 13174
 0.22
chr16_72570911_72571062 0.17 ENSG00000221286
 .
 42550
 0.18
chr3_100736189_100736340 0.17 ABI3BP
 ABI family, member 3 (NESH) binding protein
 23905
 0.23
chr12_56917827_56917978 0.17 RBMS2
 RNA binding motif, single stranded interacting protein 2
 2119
 0.23
chr18_39579349_39579630 0.17 PIK3C3
 phosphatidylinositol 3-kinase, catalytic subunit type 3
 25806
 0.28
chr19_15321258_15321624 0.17 NOTCH3
 notch 3
 9649
 0.16
chr3_171704686_171704902 0.17 FNDC3B
 fibronectin type III domain containing 3B
 52624
 0.15

Histogram of CRE-TSS distances for CREs targeted by :

Histogram of

Rank distribution of CRE target scores:

Histogram of target CRE score.

Distribution of target CREs across different genomic regions:

Weighted Piechart of Weighted Piechart of Weighted Piechart of

Network of associatons between targets according to the STRING database.

First level regulatory network of SOX17

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0019934 cGMP-mediated signaling(GO:0019934)
0.1 0.3 GO:0014012 peripheral nervous system axon regeneration(GO:0014012)
0.1 0.3 GO:0007221 positive regulation of transcription of Notch receptor target(GO:0007221)
0.1 0.4 GO:0071731 response to nitric oxide(GO:0071731)
0.1 0.2 GO:0051305 chromosome movement towards spindle pole(GO:0051305)
0.1 0.2 GO:0010766 negative regulation of sodium ion transport(GO:0010766)
0.1 0.3 GO:0043589 skin morphogenesis(GO:0043589)
0.1 0.4 GO:0007171 activation of transmembrane receptor protein tyrosine kinase activity(GO:0007171)
0.1 0.2 GO:0035581 sequestering of extracellular ligand from receptor(GO:0035581) sequestering of TGFbeta in extracellular matrix(GO:0035583) protein localization to extracellular region(GO:0071692) maintenance of protein location in extracellular region(GO:0071694) extracellular regulation of signal transduction(GO:1900115) extracellular negative regulation of signal transduction(GO:1900116)
0.1 0.2 GO:0031665 negative regulation of lipopolysaccharide-mediated signaling pathway(GO:0031665)
0.1 0.2 GO:0060666 dichotomous subdivision of terminal units involved in salivary gland branching(GO:0060666)
0.1 0.2 GO:0009756 carbohydrate mediated signaling(GO:0009756)
0.1 0.3 GO:0060997 dendritic spine morphogenesis(GO:0060997) regulation of dendritic spine morphogenesis(GO:0061001) dendritic spine organization(GO:0097061)
0.1 0.3 GO:0048625 myoblast fate commitment(GO:0048625)
0.1 0.2 GO:0060394 negative regulation of pathway-restricted SMAD protein phosphorylation(GO:0060394)
0.1 0.1 GO:0019511 peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401) 4-hydroxyproline metabolic process(GO:0019471) peptidyl-proline hydroxylation(GO:0019511)
0.1 0.2 GO:0070050 neuron cellular homeostasis(GO:0070050)
0.0 0.2 GO:0051497 negative regulation of stress fiber assembly(GO:0051497)
0.0 0.0 GO:0060594 mammary gland specification(GO:0060594)
0.0 0.2 GO:0051014 actin filament severing(GO:0051014)
0.0 0.2 GO:2000831 corticosteroid hormone secretion(GO:0035930) regulation of steroid hormone secretion(GO:2000831) regulation of corticosteroid hormone secretion(GO:2000846)
0.0 0.1 GO:0032344 regulation of ketone biosynthetic process(GO:0010566) regulation of aldosterone metabolic process(GO:0032344) regulation of aldosterone biosynthetic process(GO:0032347)
0.0 0.2 GO:0060665 regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling(GO:0060665)
0.0 0.3 GO:0045652 regulation of megakaryocyte differentiation(GO:0045652) regulation of hematopoietic progenitor cell differentiation(GO:1901532)
0.0 0.1 GO:0060083 smooth muscle contraction involved in micturition(GO:0060083)
0.0 0.1 GO:0002043 blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:0002043)
0.0 0.0 GO:0072201 negative regulation of mesenchymal cell proliferation(GO:0072201)
0.0 0.2 GO:0060390 regulation of SMAD protein import into nucleus(GO:0060390)
0.0 0.0 GO:0009151 purine deoxyribonucleotide metabolic process(GO:0009151)
0.0 0.1 GO:0045627 positive regulation of T-helper 1 cell differentiation(GO:0045627)
0.0 0.2 GO:0045662 negative regulation of myoblast differentiation(GO:0045662)
0.0 0.1 GO:0060013 righting reflex(GO:0060013)
0.0 0.2 GO:0048520 positive regulation of behavior(GO:0048520)
0.0 0.1 GO:0097531 mast cell chemotaxis(GO:0002551) regulation of mast cell chemotaxis(GO:0060753) positive regulation of mast cell chemotaxis(GO:0060754) mast cell migration(GO:0097531)
0.0 0.1 GO:0006663 platelet activating factor biosynthetic process(GO:0006663)
0.0 0.0 GO:0045188 circadian sleep/wake cycle, non-REM sleep(GO:0042748) regulation of circadian sleep/wake cycle, non-REM sleep(GO:0045188)
0.0 0.1 GO:0035929 steroid hormone secretion(GO:0035929)
0.0 0.1 GO:0046121 deoxyribonucleoside catabolic process(GO:0046121)
0.0 0.1 GO:0061318 renal filtration cell differentiation(GO:0061318) glomerular epithelium development(GO:0072010) glomerular visceral epithelial cell differentiation(GO:0072112) glomerular epithelial cell differentiation(GO:0072311)
0.0 0.1 GO:0060129 thyroid-stimulating hormone-secreting cell differentiation(GO:0060129)
0.0 0.2 GO:2000095 regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000095)
0.0 0.1 GO:0051988 regulation of attachment of spindle microtubules to kinetochore(GO:0051988)
0.0 0.0 GO:0035844 cloaca development(GO:0035844) cloacal septation(GO:0060197)
0.0 0.1 GO:0051124 synaptic growth at neuromuscular junction(GO:0051124)
0.0 0.3 GO:0034446 substrate adhesion-dependent cell spreading(GO:0034446)
0.0 0.1 GO:0010996 response to auditory stimulus(GO:0010996) auditory behavior(GO:0031223)
0.0 0.1 GO:0045425 positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process(GO:0045425)
0.0 0.0 GO:0045992 negative regulation of embryonic development(GO:0045992)
0.0 0.1 GO:0010757 negative regulation of plasminogen activation(GO:0010757)
0.0 0.0 GO:0060839 endothelial cell fate commitment(GO:0060839)
0.0 0.1 GO:0015705 iodide transport(GO:0015705)
0.0 0.1 GO:0042637 catagen(GO:0042637)
0.0 0.1 GO:0009649 entrainment of circadian clock(GO:0009649)
0.0 0.2 GO:0008354 germ cell migration(GO:0008354)
0.0 0.1 GO:0048149 behavioral response to ethanol(GO:0048149)
0.0 0.1 GO:0007258 JUN phosphorylation(GO:0007258)
0.0 0.1 GO:0097576 vacuole fusion(GO:0097576)
0.0 0.1 GO:1903672 positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050) positive regulation of sprouting angiogenesis(GO:1903672)
0.0 0.1 GO:0014721 voluntary skeletal muscle contraction(GO:0003010) twitch skeletal muscle contraction(GO:0014721)
0.0 0.1 GO:0044413 evasion or tolerance of host defenses by virus(GO:0019049) avoidance of host defenses(GO:0044413) evasion or tolerance of host defenses(GO:0044415) avoidance of defenses of other organism involved in symbiotic interaction(GO:0051832) evasion or tolerance of defenses of other organism involved in symbiotic interaction(GO:0051834)
0.0 0.2 GO:1901976 regulation of cell cycle checkpoint(GO:1901976)
0.0 0.1 GO:0071318 cellular response to ATP(GO:0071318)
0.0 0.0 GO:0060437 lung growth(GO:0060437)
0.0 0.1 GO:0006654 phosphatidic acid biosynthetic process(GO:0006654)
0.0 0.2 GO:0043206 extracellular fibril organization(GO:0043206) fibril organization(GO:0097435)
0.0 0.1 GO:0060687 regulation of branching involved in prostate gland morphogenesis(GO:0060687)
0.0 0.1 GO:0006391 transcription initiation from mitochondrial promoter(GO:0006391)
0.0 0.1 GO:0009169 purine nucleoside monophosphate catabolic process(GO:0009128) ribonucleoside monophosphate catabolic process(GO:0009158) purine ribonucleoside monophosphate catabolic process(GO:0009169)
0.0 0.1 GO:0002023 reduction of food intake in response to dietary excess(GO:0002023)
0.0 0.1 GO:0048170 positive regulation of long-term neuronal synaptic plasticity(GO:0048170)
0.0 0.2 GO:0048844 artery morphogenesis(GO:0048844)
0.0 0.1 GO:0045091 regulation of single stranded viral RNA replication via double stranded DNA intermediate(GO:0045091)
0.0 0.0 GO:0050965 detection of temperature stimulus involved in sensory perception(GO:0050961) detection of temperature stimulus involved in sensory perception of pain(GO:0050965)
0.0 0.2 GO:0009396 folic acid-containing compound biosynthetic process(GO:0009396)
0.0 0.1 GO:0008228 opsonization(GO:0008228)
0.0 0.0 GO:0060449 bud elongation involved in lung branching(GO:0060449)
0.0 0.0 GO:0021800 cerebral cortex tangential migration(GO:0021800)
0.0 0.1 GO:0019532 oxalate transport(GO:0019532)
0.0 0.0 GO:0010159 specification of organ position(GO:0010159)
0.0 0.1 GO:0031657 regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition of mitotic cell cycle(GO:0031657) positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition of mitotic cell cycle(GO:0031659)
0.0 0.2 GO:0000052 citrulline metabolic process(GO:0000052)
0.0 0.0 GO:0060435 bronchiole development(GO:0060435)
0.0 0.1 GO:0051387 negative regulation of neurotrophin TRK receptor signaling pathway(GO:0051387)
0.0 0.0 GO:0048845 venous blood vessel morphogenesis(GO:0048845)
0.0 0.1 GO:0046487 glyoxylate metabolic process(GO:0046487)
0.0 0.1 GO:0008615 pyridoxine metabolic process(GO:0008614) pyridoxine biosynthetic process(GO:0008615) vitamin B6 metabolic process(GO:0042816) vitamin B6 biosynthetic process(GO:0042819)
0.0 0.0 GO:0021508 floor plate formation(GO:0021508)
0.0 0.1 GO:0046485 ether lipid metabolic process(GO:0046485)
0.0 0.1 GO:0006216 cytidine catabolic process(GO:0006216) cytidine deamination(GO:0009972) cytidine metabolic process(GO:0046087)
0.0 0.0 GO:0045162 clustering of voltage-gated sodium channels(GO:0045162)
0.0 0.1 GO:0048680 positive regulation of axon regeneration(GO:0048680) positive regulation of neuron projection regeneration(GO:0070572)
0.0 0.0 GO:0070254 mucus secretion(GO:0070254)
0.0 0.0 GO:0061298 retina vasculature development in camera-type eye(GO:0061298) retina vasculature morphogenesis in camera-type eye(GO:0061299)
0.0 0.1 GO:0010842 retina layer formation(GO:0010842)
0.0 0.1 GO:0046952 ketone body catabolic process(GO:0046952)
0.0 0.2 GO:0030949 positive regulation of vascular endothelial growth factor receptor signaling pathway(GO:0030949)
0.0 0.1 GO:0090281 negative regulation of calcium ion import(GO:0090281) negative regulation of cation transmembrane transport(GO:1904063)
0.0 0.0 GO:0021823 cerebral cortex tangential migration using cell-cell interactions(GO:0021823) substrate-dependent cerebral cortex tangential migration(GO:0021825) postnatal olfactory bulb interneuron migration(GO:0021827)
0.0 0.1 GO:0055098 response to low-density lipoprotein particle(GO:0055098)
0.0 0.1 GO:0021670 lateral ventricle development(GO:0021670)
0.0 0.1 GO:0033600 negative regulation of mammary gland epithelial cell proliferation(GO:0033600)
0.0 0.2 GO:0043277 apoptotic cell clearance(GO:0043277)
0.0 0.1 GO:0008049 male courtship behavior(GO:0008049)
0.0 0.3 GO:0045104 intermediate filament cytoskeleton organization(GO:0045104)
0.0 0.0 GO:0032227 negative regulation of synaptic transmission, dopaminergic(GO:0032227)
0.0 0.1 GO:0051290 protein heterotetramerization(GO:0051290)
0.0 0.1 GO:0060996 dendritic spine development(GO:0060996)
0.0 0.2 GO:0045749 obsolete negative regulation of S phase of mitotic cell cycle(GO:0045749)
0.0 0.1 GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.0 0.0 GO:0002540 arachidonic acid metabolite production involved in inflammatory response(GO:0002538) leukotriene production involved in inflammatory response(GO:0002540)
0.0 0.3 GO:0018904 glycerol ether metabolic process(GO:0006662) ether metabolic process(GO:0018904)
0.0 0.1 GO:0042921 glucocorticoid receptor signaling pathway(GO:0042921)
0.0 0.2 GO:0007274 neuromuscular synaptic transmission(GO:0007274)
0.0 0.1 GO:0009200 deoxyribonucleoside triphosphate metabolic process(GO:0009200)
0.0 0.2 GO:0015701 bicarbonate transport(GO:0015701)
0.0 0.0 GO:0090081 regulation of heart induction by regulation of canonical Wnt signaling pathway(GO:0090081)
0.0 0.1 GO:0006552 leucine catabolic process(GO:0006552)
0.0 0.1 GO:0046607 positive regulation of centrosome cycle(GO:0046607)
0.0 0.1 GO:0060612 adipose tissue development(GO:0060612)
0.0 0.1 GO:0030579 ubiquitin-dependent SMAD protein catabolic process(GO:0030579)
0.0 0.2 GO:0045600 positive regulation of fat cell differentiation(GO:0045600)
0.0 0.1 GO:0033327 Leydig cell differentiation(GO:0033327)
0.0 0.0 GO:0016242 negative regulation of macroautophagy(GO:0016242)
0.0 0.0 GO:0071502 cellular response to temperature stimulus(GO:0071502)
0.0 0.1 GO:0042487 regulation of odontogenesis of dentin-containing tooth(GO:0042487)
0.0 0.1 GO:0016322 neuron remodeling(GO:0016322)
0.0 0.1 GO:0060710 chorio-allantoic fusion(GO:0060710)
0.0 0.1 GO:0090136 epithelial cell-cell adhesion(GO:0090136)
0.0 0.1 GO:0032288 myelin assembly(GO:0032288)
0.0 0.2 GO:0048010 vascular endothelial growth factor receptor signaling pathway(GO:0048010)
0.0 0.1 GO:0051547 regulation of keratinocyte migration(GO:0051547) positive regulation of keratinocyte migration(GO:0051549)
0.0 0.1 GO:0033144 negative regulation of intracellular steroid hormone receptor signaling pathway(GO:0033144)
0.0 0.0 GO:0060762 regulation of branching involved in mammary gland duct morphogenesis(GO:0060762)
0.0 0.0 GO:0001996 positive regulation of heart rate by epinephrine-norepinephrine(GO:0001996)
0.0 0.2 GO:0021846 cell proliferation in forebrain(GO:0021846)
0.0 0.1 GO:0015889 cobalamin transport(GO:0015889)
0.0 0.0 GO:0000103 sulfate assimilation(GO:0000103)
0.0 0.0 GO:0007501 mesodermal cell fate specification(GO:0007501)
0.0 0.1 GO:0030321 transepithelial chloride transport(GO:0030321)
0.0 0.0 GO:0007500 mesodermal cell fate determination(GO:0007500)
0.0 0.0 GO:0000491 small nucleolar ribonucleoprotein complex assembly(GO:0000491) box C/D snoRNP assembly(GO:0000492)
0.0 0.0 GO:0006651 diacylglycerol biosynthetic process(GO:0006651)
0.0 0.1 GO:0007185 transmembrane receptor protein tyrosine phosphatase signaling pathway(GO:0007185)
0.0 0.1 GO:0007021 tubulin complex assembly(GO:0007021)
0.0 0.0 GO:0010193 response to ozone(GO:0010193)
0.0 0.0 GO:0045077 negative regulation of interferon-gamma biosynthetic process(GO:0045077)
0.0 0.0 GO:0031958 corticosteroid receptor signaling pathway(GO:0031958)
0.0 0.1 GO:0042574 retinal metabolic process(GO:0042574)
0.0 0.1 GO:0032780 negative regulation of ATPase activity(GO:0032780)
0.0 0.1 GO:0006398 mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398)
0.0 0.1 GO:0002070 epithelial cell maturation(GO:0002070)
0.0 0.0 GO:0032927 positive regulation of activin receptor signaling pathway(GO:0032927)
0.0 0.0 GO:0048539 bone marrow development(GO:0048539)
0.0 0.0 GO:0017121 phospholipid scrambling(GO:0017121)
0.0 0.0 GO:0045906 negative regulation of vasoconstriction(GO:0045906)
0.0 0.1 GO:0001547 antral ovarian follicle growth(GO:0001547)
0.0 0.0 GO:0051459 corticotropin secretion(GO:0051458) regulation of corticotropin secretion(GO:0051459) positive regulation of corticotropin secretion(GO:0051461)
0.0 0.1 GO:0050916 sensory perception of sweet taste(GO:0050916)
0.0 0.1 GO:0019369 arachidonic acid metabolic process(GO:0019369)
0.0 0.3 GO:0010811 positive regulation of cell-substrate adhesion(GO:0010811)
0.0 0.1 GO:0090162 establishment of epithelial cell polarity(GO:0090162)
0.0 0.0 GO:0048003 antigen processing and presentation of lipid antigen via MHC class Ib(GO:0048003)
0.0 0.1 GO:0043302 positive regulation of mast cell activation involved in immune response(GO:0033008) positive regulation of leukocyte degranulation(GO:0043302) positive regulation of mast cell degranulation(GO:0043306)
0.0 0.0 GO:0000959 mitochondrial RNA metabolic process(GO:0000959) transcription from mitochondrial promoter(GO:0006390)
0.0 0.1 GO:0070327 thyroid hormone transport(GO:0070327)
0.0 0.0 GO:1903224 endodermal cell fate specification(GO:0001714) regulation of endodermal cell fate specification(GO:0042663) regulation of endodermal cell differentiation(GO:1903224)
0.0 0.0 GO:0009448 gamma-aminobutyric acid metabolic process(GO:0009448)
0.0 0.1 GO:0015802 basic amino acid transport(GO:0015802)
0.0 0.0 GO:0048702 embryonic neurocranium morphogenesis(GO:0048702)
0.0 0.2 GO:0030199 collagen fibril organization(GO:0030199)
0.0 0.0 GO:0010661 positive regulation of muscle cell apoptotic process(GO:0010661) positive regulation of smooth muscle cell apoptotic process(GO:0034393)
0.0 0.1 GO:0071360 cellular response to exogenous dsRNA(GO:0071360)
0.0 0.1 GO:0002282 microglial cell activation involved in immune response(GO:0002282)
0.0 0.0 GO:0060648 mammary gland bud morphogenesis(GO:0060648)
0.0 0.0 GO:0009120 deoxyribonucleoside metabolic process(GO:0009120)
0.0 0.0 GO:0046476 glycosylceramide biosynthetic process(GO:0046476)
0.0 0.1 GO:0031641 regulation of myelination(GO:0031641)
0.0 0.0 GO:0090084 negative regulation of inclusion body assembly(GO:0090084)
0.0 0.0 GO:0002281 macrophage activation involved in immune response(GO:0002281)
0.0 0.1 GO:0006572 tyrosine catabolic process(GO:0006572)
0.0 0.0 GO:0046501 protoporphyrinogen IX metabolic process(GO:0046501)
0.0 0.0 GO:0048875 surfactant homeostasis(GO:0043129) chemical homeostasis within a tissue(GO:0048875)
0.0 0.0 GO:0060638 mesenchymal-epithelial cell signaling(GO:0060638)
0.0 0.0 GO:0010507 negative regulation of autophagy(GO:0010507)
0.0 0.0 GO:0008053 mitochondrial fusion(GO:0008053)
0.0 0.0 GO:0071379 cellular response to prostaglandin stimulus(GO:0071379)
0.0 0.1 GO:0006853 carnitine shuttle(GO:0006853) carnitine transmembrane transport(GO:1902603)
0.0 0.0 GO:0032909 transforming growth factor beta2 production(GO:0032906) regulation of transforming growth factor beta2 production(GO:0032909)
0.0 0.0 GO:0043173 nucleotide salvage(GO:0043173)
0.0 0.0 GO:0060159 regulation of dopamine receptor signaling pathway(GO:0060159)
0.0 0.1 GO:0071320 cellular response to cAMP(GO:0071320)
0.0 0.0 GO:0035461 vitamin transmembrane transport(GO:0035461)
0.0 0.0 GO:0045347 negative regulation of MHC class II biosynthetic process(GO:0045347)
0.0 0.0 GO:0051045 negative regulation of membrane protein ectodomain proteolysis(GO:0051045)
0.0 0.0 GO:0003321 positive regulation of blood pressure by epinephrine-norepinephrine(GO:0003321)
0.0 0.0 GO:0055089 fatty acid homeostasis(GO:0055089)
0.0 0.0 GO:0032226 positive regulation of synaptic transmission, dopaminergic(GO:0032226)
0.0 0.0 GO:0006828 manganese ion transport(GO:0006828)
0.0 0.0 GO:0007621 negative regulation of female receptivity(GO:0007621)
0.0 0.0 GO:0040037 negative regulation of fibroblast growth factor receptor signaling pathway(GO:0040037)
0.0 0.0 GO:0030538 embryonic genitalia morphogenesis(GO:0030538)
0.0 0.2 GO:0030574 collagen catabolic process(GO:0030574)
0.0 0.0 GO:0051409 response to nitrosative stress(GO:0051409)
0.0 0.0 GO:0006927 obsolete transformed cell apoptotic process(GO:0006927)
0.0 0.0 GO:0071034 CUT catabolic process(GO:0071034) CUT metabolic process(GO:0071043)
0.0 0.0 GO:0032007 negative regulation of TOR signaling(GO:0032007)
0.0 0.0 GO:0051447 negative regulation of meiotic cell cycle(GO:0051447)
0.0 0.1 GO:0006048 UDP-N-acetylglucosamine biosynthetic process(GO:0006048)
0.0 0.0 GO:0021591 ventricular system development(GO:0021591)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0030056 hemidesmosome(GO:0030056)
0.1 0.2 GO:0005862 muscle thin filament tropomyosin(GO:0005862)
0.1 0.2 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.0 0.1 GO:0098647 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.0 0.1 GO:0043259 laminin-10 complex(GO:0043259)
0.0 0.3 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.0 0.1 GO:0071664 catenin-TCF7L2 complex(GO:0071664)
0.0 0.1 GO:0032449 CBM complex(GO:0032449)
0.0 0.3 GO:0005614 interstitial matrix(GO:0005614)
0.0 0.2 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.0 0.4 GO:0005583 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.0 0.1 GO:0036126 outer dense fiber(GO:0001520) sperm flagellum(GO:0036126)
0.0 0.1 GO:0030934 anchoring collagen complex(GO:0030934)
0.0 0.2 GO:0098645 network-forming collagen trimer(GO:0098642) collagen network(GO:0098645)
0.0 0.2 GO:0001527 microfibril(GO:0001527)
0.0 0.1 GO:0033268 node of Ranvier(GO:0033268)
0.0 0.1 GO:0016342 catenin complex(GO:0016342)
0.0 0.1 GO:0005899 insulin receptor complex(GO:0005899)
0.0 0.1 GO:0031232 extrinsic component of external side of plasma membrane(GO:0031232)
0.0 0.0 GO:0005787 signal peptidase complex(GO:0005787)
0.0 0.3 GO:0032420 stereocilium(GO:0032420)
0.0 0.1 GO:0001917 photoreceptor inner segment(GO:0001917)
0.0 0.1 GO:0033018 sarcoplasmic reticulum lumen(GO:0033018)
0.0 0.0 GO:0044298 neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.0 0.1 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0 0.0 GO:0005915 zonula adherens(GO:0005915)
0.0 0.1 GO:0005577 fibrinogen complex(GO:0005577)
0.0 0.1 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.0 0.1 GO:0031233 intrinsic component of external side of plasma membrane(GO:0031233)
0.0 0.0 GO:0008282 ATP-sensitive potassium channel complex(GO:0008282)
0.0 0.1 GO:0005581 collagen trimer(GO:0005581)
0.0 0.1 GO:0001950 obsolete plasma membrane enriched fraction(GO:0001950)
0.0 0.5 GO:0031903 peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.0 0.0 GO:0043205 fibril(GO:0043205)
0.0 0.0 GO:0005945 6-phosphofructokinase complex(GO:0005945)
0.0 0.0 GO:0070852 cell body fiber(GO:0070852)
0.0 0.1 GO:0031430 M band(GO:0031430)
0.0 0.0 GO:0000176 nuclear exosome (RNase complex)(GO:0000176)
0.0 0.1 GO:0043256 laminin complex(GO:0043256)
0.0 0.1 GO:0005916 fascia adherens(GO:0005916)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.1 0.3 GO:0051637 obsolete Gram-positive bacterial cell surface binding(GO:0051637)
0.1 0.5 GO:0004908 interleukin-1 receptor activity(GO:0004908)
0.1 0.2 GO:0042577 lipid phosphatase activity(GO:0042577)
0.1 0.2 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.1 0.2 GO:0005010 insulin-like growth factor-activated receptor activity(GO:0005010)
0.1 0.2 GO:0042808 obsolete neuronal Cdc2-like kinase binding(GO:0042808)
0.1 0.2 GO:0001099 basal transcription machinery binding(GO:0001098) basal RNA polymerase II transcription machinery binding(GO:0001099)
0.1 0.2 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.0 0.2 GO:1901567 icosanoid binding(GO:0050542) fatty acid derivative binding(GO:1901567)
0.0 0.1 GO:0016623 oxidoreductase activity, acting on the aldehyde or oxo group of donors, oxygen as acceptor(GO:0016623)
0.0 0.1 GO:0004117 calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117)
0.0 0.2 GO:0016934 extracellular-glycine-gated ion channel activity(GO:0016933) extracellular-glycine-gated chloride channel activity(GO:0016934)
0.0 0.1 GO:0004705 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.0 0.1 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.0 0.2 GO:0070696 transmembrane receptor protein serine/threonine kinase binding(GO:0070696)
0.0 0.2 GO:0005021 vascular endothelial growth factor-activated receptor activity(GO:0005021)
0.0 0.2 GO:0004791 thioredoxin-disulfide reductase activity(GO:0004791)
0.0 0.1 GO:0042978 ornithine decarboxylase activator activity(GO:0042978)
0.0 0.1 GO:0043559 insulin binding(GO:0043559)
0.0 0.4 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.0 0.1 GO:0003680 AT DNA binding(GO:0003680)
0.0 0.1 GO:0004720 protein-lysine 6-oxidase activity(GO:0004720)
0.0 0.1 GO:0030297 transmembrane receptor protein tyrosine kinase activator activity(GO:0030297)
0.0 0.2 GO:0005161 platelet-derived growth factor receptor binding(GO:0005161)
0.0 0.2 GO:0001609 G-protein coupled adenosine receptor activity(GO:0001609)
0.0 0.2 GO:0017080 sodium channel regulator activity(GO:0017080)
0.0 0.2 GO:0015280 ligand-gated sodium channel activity(GO:0015280)
0.0 0.4 GO:0005523 tropomyosin binding(GO:0005523)
0.0 0.1 GO:0032052 bile acid binding(GO:0032052)
0.0 0.1 GO:0045545 syndecan binding(GO:0045545)
0.0 0.1 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0 0.1 GO:0017159 pantetheine hydrolase activity(GO:0017159)
0.0 0.1 GO:0009374 biotin binding(GO:0009374)
0.0 0.1 GO:0042805 actinin binding(GO:0042805)
0.0 0.1 GO:0070052 collagen V binding(GO:0070052)
0.0 0.1 GO:0008273 calcium, potassium:sodium antiporter activity(GO:0008273)
0.0 0.2 GO:0017166 vinculin binding(GO:0017166)
0.0 0.1 GO:0048027 mRNA 5'-UTR binding(GO:0048027)
0.0 0.3 GO:0004467 long-chain fatty acid-CoA ligase activity(GO:0004467)
0.0 0.2 GO:0005172 vascular endothelial growth factor receptor binding(GO:0005172)
0.0 0.1 GO:0005534 galactose binding(GO:0005534)
0.0 0.1 GO:0016509 long-chain-3-hydroxyacyl-CoA dehydrogenase activity(GO:0016509)
0.0 0.2 GO:0003708 retinoic acid receptor activity(GO:0003708)
0.0 0.1 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.0 0.2 GO:0016813 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
0.0 0.1 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 0.1 GO:0004157 dihydropyrimidinase activity(GO:0004157)
0.0 0.3 GO:0051010 microtubule plus-end binding(GO:0051010)
0.0 0.1 GO:0004470 malic enzyme activity(GO:0004470)
0.0 0.1 GO:0010485 H4 histone acetyltransferase activity(GO:0010485)
0.0 0.1 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.0 0.0 GO:0022821 potassium ion antiporter activity(GO:0022821)
0.0 0.7 GO:0005518 collagen binding(GO:0005518)
0.0 0.4 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.0 0.2 GO:0045294 alpha-catenin binding(GO:0045294)
0.0 0.0 GO:0050543 icosatetraenoic acid binding(GO:0050543)
0.0 0.1 GO:0050501 hyaluronan synthase activity(GO:0050501)
0.0 0.1 GO:0030235 nitric-oxide synthase regulator activity(GO:0030235)
0.0 0.1 GO:0016724 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.0 0.0 GO:0005006 epidermal growth factor-activated receptor activity(GO:0005006)
0.0 0.1 GO:0071553 uridine nucleotide receptor activity(GO:0015065) G-protein coupled pyrimidinergic nucleotide receptor activity(GO:0071553)
0.0 0.1 GO:0000268 peroxisome targeting sequence binding(GO:0000268)
0.0 0.1 GO:0045499 chemorepellent activity(GO:0045499)
0.0 0.2 GO:0001871 pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.0 0.1 GO:0047429 nucleoside-triphosphate diphosphatase activity(GO:0047429)
0.0 0.0 GO:0050253 retinyl-palmitate esterase activity(GO:0050253)
0.0 0.1 GO:0004477 methenyltetrahydrofolate cyclohydrolase activity(GO:0004477)
0.0 0.8 GO:0008009 chemokine activity(GO:0008009)
0.0 0.1 GO:0017162 aryl hydrocarbon receptor binding(GO:0017162)
0.0 0.2 GO:0019992 diacylglycerol binding(GO:0019992)
0.0 0.1 GO:0001846 opsonin binding(GO:0001846)
0.0 0.1 GO:0015016 [heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
0.0 0.1 GO:0048018 receptor agonist activity(GO:0048018)
0.0 0.1 GO:0050508 glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0050508)
0.0 0.1 GO:0033130 acetylcholine receptor binding(GO:0033130)
0.0 0.1 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
0.0 0.0 GO:0005017 platelet-derived growth factor-activated receptor activity(GO:0005017)
0.0 0.0 GO:0016972 thiol oxidase activity(GO:0016972)
0.0 0.1 GO:0005123 death receptor binding(GO:0005123)
0.0 0.0 GO:0033743 peptide-methionine (R)-S-oxide reductase activity(GO:0033743)
0.0 0.0 GO:0004995 tachykinin receptor activity(GO:0004995)
0.0 0.1 GO:0001085 RNA polymerase II transcription factor binding(GO:0001085)
0.0 0.1 GO:0070290 N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.0 0.1 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.0 0.1 GO:0003696 satellite DNA binding(GO:0003696)
0.0 0.1 GO:0004616 phosphogluconate dehydrogenase (decarboxylating) activity(GO:0004616)
0.0 0.1 GO:0004982 N-formyl peptide receptor activity(GO:0004982)
0.0 0.0 GO:0032296 ribonuclease III activity(GO:0004525) double-stranded RNA-specific ribonuclease activity(GO:0032296)
0.0 0.1 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
0.0 0.1 GO:0016635 oxidoreductase activity, acting on the CH-CH group of donors, quinone or related compound as acceptor(GO:0016635)
0.0 0.0 GO:0005324 long-chain fatty acid transporter activity(GO:0005324)
0.0 0.0 GO:0003829 beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity(GO:0003829)
0.0 0.1 GO:0047184 1-acylglycerophosphocholine O-acyltransferase activity(GO:0047184)
0.0 0.1 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.0 0.1 GO:0004366 glycerol-3-phosphate O-acyltransferase activity(GO:0004366)
0.0 0.2 GO:0035035 histone acetyltransferase binding(GO:0035035)
0.0 0.1 GO:0004340 glucokinase activity(GO:0004340)
0.0 0.0 GO:0017128 phospholipid scramblase activity(GO:0017128)
0.0 0.1 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.0 0.1 GO:0019864 IgG binding(GO:0019864)
0.0 0.1 GO:0001968 fibronectin binding(GO:0001968)
0.0 0.1 GO:0004716 receptor signaling protein tyrosine kinase activity(GO:0004716)
0.0 0.3 GO:0005242 inward rectifier potassium channel activity(GO:0005242)
0.0 0.1 GO:0008020 G-protein coupled photoreceptor activity(GO:0008020)
0.0 0.1 GO:0004339 glucan 1,4-alpha-glucosidase activity(GO:0004339)
0.0 0.0 GO:0016941 natriuretic peptide receptor activity(GO:0016941)
0.0 0.1 GO:0051428 peptide hormone receptor binding(GO:0051428)
0.0 0.9 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 0.1 GO:0016641 oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor(GO:0016641)
0.0 0.0 GO:0030955 potassium ion binding(GO:0030955)
0.0 0.0 GO:0031545 procollagen-proline 4-dioxygenase activity(GO:0004656) peptidyl-proline 4-dioxygenase activity(GO:0031545)
0.0 0.1 GO:0030492 hemoglobin binding(GO:0030492)
0.0 0.0 GO:0004597 peptide-aspartate beta-dioxygenase activity(GO:0004597)
0.0 0.0 GO:0030354 melanin-concentrating hormone activity(GO:0030354)
0.0 0.0 GO:0070273 phosphatidylinositol-4-phosphate binding(GO:0070273)
0.0 0.0 GO:0004645 phosphorylase activity(GO:0004645)
0.0 0.1 GO:0000339 RNA cap binding(GO:0000339)
0.0 0.0 GO:0004992 platelet activating factor receptor activity(GO:0004992)
0.0 0.0 GO:0051636 obsolete Gram-negative bacterial cell surface binding(GO:0051636)
0.0 0.2 GO:0005520 insulin-like growth factor binding(GO:0005520)
0.0 0.2 GO:0030971 receptor tyrosine kinase binding(GO:0030971) protein tyrosine kinase binding(GO:1990782)
0.0 0.0 GO:0003872 6-phosphofructokinase activity(GO:0003872)
0.0 0.1 GO:0004945 angiotensin receptor activity(GO:0001595) angiotensin type II receptor activity(GO:0004945)
0.0 0.1 GO:0017169 CDP-alcohol phosphatidyltransferase activity(GO:0017169)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.1 PID EPHRINB REV PATHWAY Ephrin B reverse signaling
0.0 0.4 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.0 0.6 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events
0.0 1.2 NABA COLLAGENS Genes encoding collagen proteins
0.0 0.2 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.0 0.1 PID SYNDECAN 1 PATHWAY Syndecan-1-mediated signaling events
0.0 0.2 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.0 0.1 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.0 0.0 ST IL 13 PATHWAY Interleukin 13 (IL-13) Pathway
0.0 0.0 SA FAS SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.0 0.3 ST GRANULE CELL SURVIVAL PATHWAY Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway.

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.1 REACTOME DAG AND IP3 SIGNALING Genes involved in DAG and IP3 signaling
0.1 0.6 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.1 0.1 REACTOME DOWNSTREAM SIGNALING EVENTS OF B CELL RECEPTOR BCR Genes involved in Downstream Signaling Events Of B Cell Receptor (BCR)
0.0 0.0 REACTOME APC C CDC20 MEDIATED DEGRADATION OF CYCLIN B Genes involved in APC/C:Cdc20 mediated degradation of Cyclin B
0.0 0.8 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.0 0.0 REACTOME BILE ACID AND BILE SALT METABOLISM Genes involved in Bile acid and bile salt metabolism
0.0 0.2 REACTOME GAP JUNCTION DEGRADATION Genes involved in Gap junction degradation
0.0 1.3 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.0 0.2 REACTOME SIGNALING BY ACTIVATED POINT MUTANTS OF FGFR1 Genes involved in Signaling by activated point mutants of FGFR1
0.0 0.2 REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.0 0.2 REACTOME P2Y RECEPTORS Genes involved in P2Y receptors
0.0 0.2 REACTOME PURINE CATABOLISM Genes involved in Purine catabolism
0.0 0.1 REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.0 0.0 REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.0 0.3 REACTOME PYRIMIDINE METABOLISM Genes involved in Pyrimidine metabolism
0.0 0.0 REACTOME FGFR4 LIGAND BINDING AND ACTIVATION Genes involved in FGFR4 ligand binding and activation
0.0 0.0 REACTOME VIRAL MESSENGER RNA SYNTHESIS Genes involved in Viral Messenger RNA Synthesis
0.0 0.1 REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK Genes involved in Regulation of Rheb GTPase activity by AMPK
0.0 0.3 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.0 0.2 REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.0 0.1 REACTOME SIGNALING BY CONSTITUTIVELY ACTIVE EGFR Genes involved in Signaling by constitutively active EGFR
0.0 0.1 REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the late endosome membrane
0.0 0.1 REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.0 0.1 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.0 0.2 REACTOME A TETRASACCHARIDE LINKER SEQUENCE IS REQUIRED FOR GAG SYNTHESIS Genes involved in A tetrasaccharide linker sequence is required for GAG synthesis
0.0 0.1 REACTOME SIGNALING BY WNT Genes involved in Signaling by Wnt
0.0 0.1 REACTOME ADP SIGNALLING THROUGH P2RY1 Genes involved in ADP signalling through P2Y purinoceptor 1
0.0 0.3 REACTOME MYOGENESIS Genes involved in Myogenesis
0.0 0.1 REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.0 0.1 REACTOME CROSS PRESENTATION OF SOLUBLE EXOGENOUS ANTIGENS ENDOSOMES Genes involved in Cross-presentation of soluble exogenous antigens (endosomes)
0.0 0.2 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.0 0.1 REACTOME ROLE OF DCC IN REGULATING APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.0 0.1 REACTOME HORMONE LIGAND BINDING RECEPTORS Genes involved in Hormone ligand-binding receptors
0.0 0.0 REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Glutamate Neurotransmitter Release Cycle
0.0 0.0 REACTOME CDK MEDIATED PHOSPHORYLATION AND REMOVAL OF CDC6 Genes involved in CDK-mediated phosphorylation and removal of Cdc6