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ENCODE: H3K4me1 ChIP-Seq of primary human cells

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CREMA is a free online tool that recognizes most important transcription factors that change the chromatin state across different samples.

Results for SOX18

Z-value: 2.02

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Transcription factors associated with SOX18

Gene Symbol	Gene ID	Gene Info
SOX18 Ensembl NCBI GeneCards UniProt	ENSG00000203883.5	SOX18

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE	Gene	Distance	Association probability	Pearson corr. coef.	P-value	Plot
SOX18	chr20_62683213_62683364	2294	0.139176	-0.84	5.0e-03	Click!
SOX18	chr20_62684335_62684486	3416	0.107379	-0.76	1.8e-02	Click!
SOX18	chr20_62684017_62684168	3098	0.113552	-0.62	7.6e-02	Click!
SOX18	chr20_62681600_62681772	692	0.441121	-0.61	7.9e-02	Click!
SOX18	chr20_62681864_62682091	983	0.313699	-0.55	1.2e-01	Click!

Activity of the SOX18 motif across conditions

Conditions sorted by the z-value of the SOX18 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE)	Target Score	Top associated gene	Gene Info	Distance of CRE to TSS	CRE/Gene association probability
chr9_96720941_96721916	0.54	BARX1	BARX homeobox 1	3774	0.31
chr16_50286306_50286457	0.52	ADCY7	adenylate cyclase 7	6333	0.22
chr17_54218727_54219172	0.48	ANKFN1	ankyrin-repeat and fibronectin type III domain containing 1	11887	0.29
chr1_101088070_101088221	0.47	GPR88	G protein-coupled receptor 88	84452	0.09
chr3_45589006_45589723	0.44	LARS2-AS1	LARS2 antisense RNA 1	38327	0.14
chr3_172076117_172076380	0.44	AC092964.1	Uncharacterized protein	42030	0.16
chr14_69563603_69563754	0.41	ENSG00000206768	.	46992	0.14
chr1_110364191_110364827	0.40	EPS8L3	EPS8-like 3	57860	0.08
chr3_50249552_50249994	0.39	GNAI2	guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2	13951	0.1
chr10_134224918_134226015	0.38	PWWP2B	PWWP domain containing 2B	14764	0.17
chr22_20904853_20905469	0.37	MED15	mediator complex subunit 15	113	0.95
chr2_151554289_151554440	0.37	RND3	Rho family GTPase 3	158839	0.04
chr11_47276308_47276801	0.37	NR1H3	nuclear receptor subfamily 1, group H, member 3	2601	0.15
chr6_126142988_126143327	0.36	NCOA7-AS1	NCOA7 antisense RNA 1	3153	0.24
chr2_9754540_9754692	0.36	ENSG00000207086	.	780	0.65
chr11_1953077_1953228	0.36	TNNT3	troponin T type 3 (skeletal, fast)	9047	0.11
chr2_190032014_190032165	0.35	COL5A2	collagen, type V, alpha 2	12516	0.22
chr10_74496065_74496270	0.35	ENSG00000266719	.	15380	0.16
chr9_140524791_140525262	0.35	EHMT1	euchromatic histone-lysine N-methyltransferase 1	11572	0.13
chr6_46159585_46159736	0.35	ENPP5	ectonucleotide pyrophosphatase/phosphodiesterase 5 (putative)	20952	0.21
chr1_9750618_9751880	0.34	RP11-558F24.4		3636	0.21
chr6_167011503_167011887	0.34	RPS6KA2	ribosomal protein S6 kinase, 90kDa, polypeptide 2	29030	0.2
chr1_56184117_56184268	0.34	PIGQP1	phosphatidylinositol glycan anchor biosynthesis, class Q pseudogene 1	220761	0.02
chr11_74385068_74385219	0.34	ENSG00000223202	.	11126	0.14
chr21_29816915_29817066	0.34	ENSG00000251894	.	298540	0.01
chr3_47844781_47845806	0.34	DHX30	DEAH (Asp-Glu-Ala-His) box helicase 30	638	0.69
chr3_57198236_57199040	0.34	IL17RD	interleukin 17 receptor D	765	0.66
chr14_50455016_50455167	0.33	C14orf182	chromosome 14 open reading frame 182	19147	0.16
chr5_92394509_92394660	0.33	ENSG00000221810	.	341364	0.01
chr8_21766211_21767399	0.33	DOK2	docking protein 2, 56kDa	4369	0.22
chr7_122315277_122315428	0.32	RNF133	ring finger protein 133	23858	0.2
chr15_49147532_49147683	0.32	SHC4	SHC (Src homology 2 domain containing) family, member 4	22079	0.14
chr6_146136305_146136901	0.32	RP11-545I5.3		169	0.88
chr7_92242355_92242506	0.32	FAM133B	family with sequence similarity 133, member B	22722	0.2
chr12_69809959_69810110	0.32	ENSG00000266185	.	15351	0.18
chr1_230298913_230299064	0.32	GALNT2	UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 2 (GalNAc-T2)	95970	0.07
chr12_49160018_49160252	0.32	RP11-579D7.2		158	0.91
chr1_120508954_120509105	0.32	RP5-1042I8.7		55793	0.13
chr7_120646986_120647158	0.32	CPED1	cadherin-like and PC-esterase domain containing 1	17396	0.19
chr3_99039376_99039527	0.32	ENSG00000266030	.	46282	0.2
chr7_105967705_105967856	0.32	NAMPT	nicotinamide phosphoribosyltransferase	41008	0.17
chr6_141057887_141058038	0.32	ENSG00000264390	.	53011	0.17
chr8_49566364_49566556	0.31	EFCAB1	EF-hand calcium binding domain 1	75888	0.12
chr7_42651177_42651328	0.31	C7orf25	chromosome 7 open reading frame 25	300257	0.01
chr3_141929081_141929232	0.31	GK5	glycerol kinase 5 (putative)	15272	0.22
chr3_197829897_197830311	0.31	AC073135.3		6973	0.18
chr2_38929120_38929654	0.31	GALM	galactose mutarotase (aldose 1-epimerase)	20950	0.15
chr14_76352765_76352916	0.31	RP11-270M14.4		38799	0.18
chr20_5953734_5953885	0.30	ENSG00000207380	.	8625	0.14
chr20_33169663_33169814	0.30	MAP1LC3A	microtubule-associated protein 1 light chain 3 alpha	23216	0.15
chr3_114618572_114618723	0.30	ZBTB20	zinc finger and BTB domain containing 20	140529	0.05
chr12_12016346_12017014	0.30	ETV6	ets variant 6	22191	0.26
chr11_121976791_121976942	0.29	RP11-166D19.1		216	0.92
chr1_25152697_25152848	0.29	ENSG00000238482	.	48302	0.14
chr12_57703986_57704137	0.29	R3HDM2	R3H domain containing 2	185	0.93
chr12_30821003_30821154	0.29	IPO8	importin 8	9016	0.29
chr20_48669207_48669555	0.29	UBE2V1	ubiquitin-conjugating enzyme E2 variant 1	60295	0.09
chr3_30272683_30272834	0.29	ENSG00000199927	.	73269	0.11
chr8_40381376_40381655	0.29	ZMAT4	zinc finger, matrin-type 4	364549	0.01
chr5_145283234_145283497	0.29	GRXCR2	glutaredoxin, cysteine rich 2	30834	0.18
chr17_1991262_1992041	0.29	RP11-667K14.5		1324	0.29
chr20_9402958_9403109	0.29	LAMP5	lysosomal-associated membrane protein family, member 5	91972	0.08
chr4_110622784_110623524	0.29	CASP6	caspase 6, apoptosis-related cysteine peptidase	851	0.59
chr5_175299080_175299718	0.29	CPLX2	complexin 2	414	0.87
chr17_30592069_30592688	0.29	RHBDL3	rhomboid, veinlet-like 3 (Drosophila)	817	0.57
chr20_45887413_45887564	0.29	ZMYND8	zinc finger, MYND-type containing 8	40156	0.12
chr17_66351031_66351337	0.29	ARSG	arylsulfatase G	63525	0.09
chr8_97155708_97155859	0.28	GDF6	growth differentiation factor 6	17237	0.24
chr11_34338329_34338672	0.28	ABTB2	ankyrin repeat and BTB (POZ) domain containing 2	40302	0.19
chr8_59870660_59870811	0.28	RP11-328K2.1		34762	0.22
chr3_66026400_66026551	0.28	MAGI1	membrane associated guanylate kinase, WW and PDZ domain containing 1	2250	0.35
chr7_100859763_100860679	0.28	ZNHIT1	zinc finger, HIT-type containing 1	728	0.34
chr15_41189915_41190066	0.28	VPS18	vacuolar protein sorting 18 homolog (S. cerevisiae)	3325	0.14
chr21_39634052_39634203	0.28	KCNJ15	potassium inwardly-rectifying channel, subfamily J, member 15	5257	0.3
chr1_16285078_16285547	0.28	ZBTB17	zinc finger and BTB domain containing 17	14389	0.13
chr6_56350288_56350439	0.28	DST	dystonin	11575	0.25
chr4_152974203_152974465	0.28	ENSG00000253077	.	81569	0.1
chr8_41113302_41113453	0.28	ENSG00000263372	.	15285	0.18
chr7_94046658_94046809	0.27	COL1A2	collagen, type I, alpha 2	22860	0.23
chr3_123380438_123380589	0.27	MYLK-AS2	MYLK antisense RNA 2	27978	0.16
chr15_50278689_50278840	0.27	ENSG00000201086	.	4124	0.29
chr5_142219088_142219352	0.27	ARHGAP26-AS1	ARHGAP26 antisense RNA 1	29255	0.22
chr11_130544827_130544978	0.27	C11orf44	chromosome 11 open reading frame 44	2051	0.48
chr12_56637690_56637841	0.27	SLC39A5	solute carrier family 39 (zinc transporter), member 5	13219	0.06
chr15_43805657_43805808	0.27	MAP1A	microtubule-associated protein 1A	2576	0.2
chr10_33671231_33671382	0.27	NRP1	neuropilin 1	46116	0.19
chr19_34944155_34944306	0.27	UBA2	ubiquitin-like modifier activating enzyme 2	3041	0.18
chr5_119942616_119942767	0.27	PRR16	proline rich 16	10092	0.31
chr12_15950766_15950967	0.27	EPS8	epidermal growth factor receptor pathway substrate 8	8356	0.28
chr4_10105956_10106688	0.27	ENSG00000223086	.	11186	0.15
chr6_81951829_81951980	0.27	RP1-300G12.2		292726	0.01
chr9_79176771_79176954	0.27	ENSG00000241781	.	9869	0.26
chr2_36731284_36731435	0.27	CRIM1	cysteine rich transmembrane BMP regulator 1 (chordin-like)	9474	0.2
chr1_180000870_180001021	0.27	CEP350	centrosomal protein 350kDa	9393	0.26
chr13_76197265_76197416	0.27	LMO7	LIM domain 7	2770	0.24
chrX_153095505_153095958	0.27	PDZD4	PDZ domain containing 4	82	0.94
chr6_20484087_20484358	0.27	ENSG00000201683	.	16184	0.16
chr4_143239248_143239399	0.27	INPP4B	inositol polyphosphate-4-phosphatase, type II, 105kDa	12226	0.33
chr2_144282406_144282636	0.27	AC096558.1		44163	0.15
chr7_134512008_134512159	0.27	CALD1	caldesmon 1	16552	0.27
chr5_76925321_76925875	0.27	WDR41	WD repeat domain 41	9162	0.23
chr5_125343454_125343605	0.27	ENSG00000265637	.	188999	0.03
chr2_28019558_28020090	0.27	AC110084.1		10638	0.17
chr9_90221967_90222321	0.26	DAPK1-IT1	DAPK1 intronic transcript 1 (non-protein coding)	53775	0.14
chr2_238105330_238105481	0.26	AC112715.2	Uncharacterized protein	60329	0.13
chr4_86713976_86714229	0.26	ARHGAP24	Rho GTPase activating protein 24	14243	0.26
chr18_54126224_54126600	0.26	TXNL1	thioredoxin-like 1	155310	0.04
chr8_59814838_59814989	0.26	ENSG00000201231	.	87802	0.09
chr19_50284218_50285014	0.26	AP2A1	adaptor-related protein complex 2, alpha 1 subunit	14225	0.07
chr5_121465328_121465547	0.26	ZNF474	zinc finger protein 474	176	0.95
chr14_45715921_45716072	0.26	MIS18BP1	MIS18 binding protein 1	6384	0.21
chrX_24415534_24415685	0.26	ENSG00000264746	.	48683	0.14
chr6_139604033_139604184	0.26	RP11-445F6.2		136	0.96
chr3_71217394_71217545	0.26	FOXP1	forkhead box P1	30063	0.25
chr5_136826313_136826580	0.26	SPOCK1	sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1	7801	0.26
chr7_134605737_134605888	0.26	CALD1	caldesmon 1	575	0.83
chr3_73650982_73651133	0.26	ENSG00000239119	.	7904	0.22
chr8_74370642_74370793	0.26	RP11-434I12.2		102021	0.07
chr21_36800534_36801386	0.26	ENSG00000211590	.	292053	0.01
chr3_141932530_141932681	0.26	GK5	glycerol kinase 5 (putative)	11823	0.23
chr18_57183703_57183854	0.26	CCBE1	collagen and calcium binding EGF domains 1	36306	0.16
chr18_41427417_41427568	0.25	ENSG00000202250	.	15262	0.31
chr5_53821237_53821474	0.25	SNX18	sorting nexin 18	7762	0.29
chr3_184503248_184503626	0.25	VPS8	vacuolar protein sorting 8 homolog (S. cerevisiae)	26494	0.22
chr14_51802616_51802767	0.25	ENSG00000201820	.	81950	0.08
chr12_50696750_50697016	0.25	AC140061.12	Uncharacterized protein	6394	0.16
chr11_69326287_69326438	0.25	CCND1	cyclin D1	129493	0.05
chr10_96977649_96977800	0.25	RP11-310E22.4		13177	0.21
chr3_42225778_42226037	0.25	TRAK1	trafficking protein, kinesin binding 1	8662	0.23
chr2_238343817_238344489	0.25	AC112721.1	Uncharacterized protein	10234	0.19
chr10_90686436_90686600	0.25	ACTA2-AS1	ACTA2 antisense RNA 1	5882	0.17
chr21_28794987_28795138	0.25	ADAMTS5	ADAM metallopeptidase with thrombospondin type 1 motif, 5	456230	0.01
chr11_64423475_64423770	0.25	AP001092.4		9751	0.15
chr18_8802021_8802172	0.25	RP11-674N23.4		442	0.85
chr2_144235573_144235784	0.25	AC096558.1		2672	0.38
chr17_39219455_39219606	0.25	KRTAP2-4	keratin associated protein 2-4	2601	0.09
chr8_61449115_61449422	0.25	RP11-91I20.4		16327	0.21
chr1_218985488_218985639	0.25	ENSG00000212610	.	270322	0.02
chr10_6184893_6185168	0.25	PFKFB3	6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3	1851	0.27
chr16_65035867_65036018	0.25	CDH11	cadherin 11, type 2, OB-cadherin (osteoblast)	57639	0.18
chr3_157051609_157051760	0.24	ENSG00000243176	.	47735	0.16
chr6_113917736_113917887	0.24	ENSG00000266650	.	6306	0.29
chr3_115121656_115121807	0.24	GAP43	growth associated protein 43	220440	0.02
chr12_3813574_3813873	0.24	ENSG00000222338	.	21770	0.23
chr2_9467115_9467266	0.24	ITGB1BP1	integrin beta 1 binding protein 1	93233	0.07
chr6_112609924_112610075	0.24	LAMA4	laminin, alpha 4	33858	0.15
chr8_42341378_42341529	0.24	SLC20A2	solute carrier family 20 (phosphate transporter), member 2	17308	0.18
chr7_157027160_157027311	0.24	ENSG00000266453	.	71252	0.1
chr1_165606379_165606530	0.24	MGST3	microsomal glutathione S-transferase 3	4977	0.21
chr15_38437640_38437791	0.24	SPRED1	sprouty-related, EVH1 domain containing 1	106812	0.08
chr2_33390887_33391038	0.24	LTBP1	latent transforming growth factor beta binding protein 1	31238	0.23
chr13_94976978_94977370	0.24	GPC6-AS1	GPC6 antisense RNA 1	136929	0.05
chr6_140071935_140072086	0.24	CITED2	Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2	376253	0.01
chr11_128685529_128685949	0.24	KCNJ1	potassium inwardly-rectifying channel, subfamily J, member 1	26690	0.17
chr17_28009202_28009353	0.24	RP11-68I3.11		36412	0.08
chr15_67151981_67152132	0.24	SMAD6	SMAD family member 6	148021	0.04
chr3_73651821_73651972	0.24	ENSG00000239119	.	8743	0.21
chr10_33560861_33561012	0.24	NRP1	neuropilin 1	8304	0.23
chr2_194421738_194421889	0.24	NA	NA	> 10⁶	NA
chr17_71068721_71068930	0.24	SLC39A11	solute carrier family 39, member 11	17078	0.24
chr10_79314561_79314733	0.24	ENSG00000199592	.	32160	0.21
chr12_69736284_69736540	0.24	LYZ	lysozyme	5709	0.18
chr22_46828002_46828543	0.24	TRMU	tRNA 5-methylaminomethyl-2-thiouridylate methyltransferase	96453	0.06
chr10_63855456_63855607	0.24	ENSG00000221094	.	20443	0.23
chr16_14204871_14205022	0.24	MKL2	MKL/myocardin-like 2	29536	0.21
chr14_65552013_65552503	0.24	RP11-840I19.3		3506	0.19
chr7_6298231_6298382	0.24	CYTH3	cytohesin 3	13969	0.18
chr12_22886601_22886752	0.24	ETNK1	ethanolamine kinase 1	108385	0.07
chr8_25250213_25250364	0.24	GNRH1	gonadotropin-releasing hormone 1 (luteinizing-releasing hormone)	31459	0.19
chr20_38506212_38506363	0.24	ENSG00000263518	.	225711	0.02
chr13_49942314_49942465	0.24	CAB39L	calcium binding protein 39-like	8878	0.24
chr4_95333104_95333255	0.24	PDLIM5	PDZ and LIM domain 5	39858	0.2
chr12_54954441_54955170	0.24	PDE1B	phosphodiesterase 1B, calmodulin-dependent	436	0.78
chr10_6182182_6182929	0.24	PFKFB3	6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3	4326	0.16
chr11_120198049_120198425	0.24	TMEM136	transmembrane protein 136	2221	0.28
chr19_3670862_3671279	0.24	AC004637.1		1510	0.26
chr8_49341467_49342503	0.24	ENSG00000252710	.	121395	0.06
chr1_101096233_101096384	0.24	VCAM1	vascular cell adhesion molecule 1	88990	0.08
chr2_27948220_27948371	0.23	AC074091.13	Uncharacterized protein	9696	0.15
chr10_112271045_112271196	0.23	DUSP5	dual specificity phosphatase 5	13524	0.17
chr7_134519552_134519703	0.23	CALD1	caldesmon 1	9008	0.29
chr11_130272299_130272590	0.23	ADAMTS8	ADAM metallopeptidase with thrombospondin type 1 motif, 8	26444	0.2
chr3_151089721_151089872	0.23	P2RY12	purinergic receptor P2Y, G-protein coupled, 12	12804	0.19
chr17_66374516_66374972	0.23	ENSG00000207561	.	45945	0.13
chr3_123668814_123668965	0.23	CCDC14	coiled-coil domain containing 14	467	0.84
chr3_157053187_157053338	0.23	ENSG00000243176	.	49313	0.16
chr1_201526375_201526526	0.23	CSRP1	cysteine and glycine-rich protein 1	47866	0.1
chr11_121910604_121910755	0.23	RP11-166D19.1		30185	0.16
chr12_67829098_67829363	0.23	CAND1	cullin-associated and neddylation-dissociated 1	136478	0.05
chr5_56733706_56733857	0.23	CTD-2023N9.1		42894	0.15
chr2_112908674_112908866	0.23	FBLN7	fibulin 7	8555	0.25
chr11_114178834_114179221	0.23	NNMT	nicotinamide N-methyltransferase	10154	0.21
chr2_204773964_204774580	0.23	ICOS	inducible T-cell co-stimulator	27199	0.21
chrX_15871864_15872537	0.23	AP1S2	adaptor-related protein complex 1, sigma 2 subunit	727	0.72
chr12_19727844_19727995	0.23	AEBP2	AE binding protein 2	74856	0.12
chrX_77913775_77914536	0.23	ZCCHC5	zinc finger, CCHC domain containing 5	670	0.82
chr9_12794120_12794271	0.23	LURAP1L	leucine rich adaptor protein 1-like	19175	0.18
chr2_160474235_160474607	0.23	BAZ2B	bromodomain adjacent to zinc finger domain, 2B	1218	0.47
chr3_148426073_148426436	0.23	AGTR1	angiotensin II receptor, type 1	10549	0.28
chr1_100171061_100171212	0.23	PALMD	palmdelphin	59387	0.11

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of SOX18

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	0.2	GO:0060028	convergent extension involved in axis elongation(GO:0060028)
0.2	0.3	GO:0046827	positive regulation of protein export from nucleus(GO:0046827)
0.1	0.4	GO:0030210	heparin biosynthetic process(GO:0030210)
0.1	0.4	GO:0051305	chromosome movement towards spindle pole(GO:0051305)
0.1	0.1	GO:0060648	mammary gland bud morphogenesis(GO:0060648)
0.1	0.4	GO:0060665	regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling(GO:0060665)
0.1	0.2	GO:0048807	female genitalia morphogenesis(GO:0048807)
0.1	0.6	GO:0061001	dendritic spine morphogenesis(GO:0060997) regulation of dendritic spine morphogenesis(GO:0061001) dendritic spine organization(GO:0097061)
0.1	0.3	GO:0060394	negative regulation of pathway-restricted SMAD protein phosphorylation(GO:0060394)
0.1	0.2	GO:0060594	mammary gland specification(GO:0060594)
0.1	0.3	GO:0019800	peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.1	0.1	GO:0048520	positive regulation of behavior(GO:0048520)
0.1	0.3	GO:0070427	nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070427)
0.1	0.2	GO:0060638	mesenchymal-epithelial cell signaling(GO:0060638)
0.1	0.3	GO:0051497	negative regulation of stress fiber assembly(GO:0051497)
0.1	0.3	GO:0048149	behavioral response to ethanol(GO:0048149)
0.1	0.2	GO:0055098	response to low-density lipoprotein particle(GO:0055098)
0.1	0.2	GO:0002043	blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:0002043)
0.1	0.1	GO:0061042	vascular wound healing(GO:0061042) regulation of vascular wound healing(GO:0061043)
0.1	0.1	GO:0048845	venous blood vessel morphogenesis(GO:0048845)
0.1	0.2	GO:0070050	neuron cellular homeostasis(GO:0070050)
0.1	0.2	GO:0043049	otic placode formation(GO:0043049)
0.1	0.2	GO:0003078	obsolete regulation of natriuresis(GO:0003078)
0.1	0.2	GO:0060083	smooth muscle contraction involved in micturition(GO:0060083)
0.1	0.2	GO:0071692	sequestering of extracellular ligand from receptor(GO:0035581) sequestering of TGFbeta in extracellular matrix(GO:0035583) protein localization to extracellular region(GO:0071692) maintenance of protein location in extracellular region(GO:0071694) extracellular regulation of signal transduction(GO:1900115) extracellular negative regulation of signal transduction(GO:1900116)
0.1	0.2	GO:0019934	cGMP-mediated signaling(GO:0019934)
0.1	0.2	GO:0060666	dichotomous subdivision of terminal units involved in salivary gland branching(GO:0060666)
0.1	0.2	GO:0060737	prostate gland morphogenetic growth(GO:0060737)
0.1	0.2	GO:0032509	endosome transport via multivesicular body sorting pathway(GO:0032509)
0.1	0.2	GO:0015705	iodide transport(GO:0015705)
0.1	0.4	GO:0006198	cAMP catabolic process(GO:0006198)
0.1	0.2	GO:0061525	hindgut morphogenesis(GO:0007442) hindgut development(GO:0061525)
0.1	0.3	GO:0022617	extracellular matrix disassembly(GO:0022617)
0.1	0.2	GO:0031340	positive regulation of vesicle fusion(GO:0031340)
0.1	0.1	GO:0060449	bud elongation involved in lung branching(GO:0060449)
0.1	0.2	GO:0060242	contact inhibition(GO:0060242)
0.1	0.1	GO:0010193	response to ozone(GO:0010193)
0.1	0.2	GO:0030091	protein repair(GO:0030091)
0.1	0.3	GO:0006703	estrogen biosynthetic process(GO:0006703)
0.1	0.2	GO:0034638	phosphatidylcholine catabolic process(GO:0034638)
0.0	0.1	GO:0072112	renal filtration cell differentiation(GO:0061318) glomerular epithelium development(GO:0072010) glomerular visceral epithelial cell differentiation(GO:0072112) glomerular epithelial cell differentiation(GO:0072311)
0.0	0.1	GO:0048312	intracellular distribution of mitochondria(GO:0048312)
0.0	0.1	GO:0014834	skeletal muscle satellite cell maintenance involved in skeletal muscle regeneration(GO:0014834)
0.0	0.1	GO:0014012	peripheral nervous system axon regeneration(GO:0014012)
0.0	0.2	GO:2000095	regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000095)
0.0	0.1	GO:0035426	extracellular matrix-cell signaling(GO:0035426)
0.0	0.0	GO:0043117	positive regulation of vascular permeability(GO:0043117)
0.0	0.1	GO:0016115	diterpenoid catabolic process(GO:0016103) terpenoid catabolic process(GO:0016115) retinoic acid catabolic process(GO:0034653)
0.0	0.1	GO:0010757	negative regulation of plasminogen activation(GO:0010757)
0.0	0.1	GO:0060174	limb bud formation(GO:0060174)
0.0	0.1	GO:0061364	apoptotic process involved in luteolysis(GO:0061364)
0.0	0.1	GO:0045578	negative regulation of B cell differentiation(GO:0045578)
0.0	0.1	GO:0001955	blood vessel maturation(GO:0001955)
0.0	0.2	GO:0009051	pentose-phosphate shunt, oxidative branch(GO:0009051)
0.0	0.1	GO:0032328	alanine transport(GO:0032328)
0.0	0.2	GO:0009128	purine nucleoside monophosphate catabolic process(GO:0009128) ribonucleoside monophosphate catabolic process(GO:0009158) purine ribonucleoside monophosphate catabolic process(GO:0009169)
0.0	0.1	GO:0010667	striated muscle cell apoptotic process(GO:0010658) cardiac muscle cell apoptotic process(GO:0010659) regulation of striated muscle cell apoptotic process(GO:0010662) negative regulation of striated muscle cell apoptotic process(GO:0010664) regulation of cardiac muscle cell apoptotic process(GO:0010665) negative regulation of cardiac muscle cell apoptotic process(GO:0010667)
0.0	0.3	GO:0006527	arginine catabolic process(GO:0006527)
0.0	1.0	GO:0030199	collagen fibril organization(GO:0030199)
0.0	0.3	GO:0045885	obsolete positive regulation of survival gene product expression(GO:0045885)
0.0	0.0	GO:0043589	skin morphogenesis(GO:0043589)
0.0	0.1	GO:0003323	type B pancreatic cell development(GO:0003323)
0.0	0.2	GO:0060753	mast cell chemotaxis(GO:0002551) regulation of mast cell chemotaxis(GO:0060753) positive regulation of mast cell chemotaxis(GO:0060754) mast cell migration(GO:0097531)
0.0	0.0	GO:0045077	negative regulation of interferon-gamma biosynthetic process(GO:0045077)
0.0	0.1	GO:0033025	mast cell homeostasis(GO:0033023) mast cell apoptotic process(GO:0033024) regulation of mast cell apoptotic process(GO:0033025)
0.0	0.2	GO:0007028	cytoplasm organization(GO:0007028)
0.0	0.1	GO:0010566	regulation of ketone biosynthetic process(GO:0010566) regulation of aldosterone metabolic process(GO:0032344) regulation of aldosterone biosynthetic process(GO:0032347)
0.0	0.2	GO:0051124	synaptic growth at neuromuscular junction(GO:0051124)
0.0	0.0	GO:0019530	taurine metabolic process(GO:0019530)
0.0	0.2	GO:0031641	regulation of myelination(GO:0031641)
0.0	0.2	GO:0046642	negative regulation of alpha-beta T cell proliferation(GO:0046642)
0.0	0.2	GO:0071680	response to indole-3-methanol(GO:0071680) cellular response to indole-3-methanol(GO:0071681)
0.0	0.1	GO:0030505	inorganic diphosphate transport(GO:0030505)
0.0	0.1	GO:0007343	egg activation(GO:0007343)
0.0	0.2	GO:0035414	negative regulation of catenin import into nucleus(GO:0035414)
0.0	0.6	GO:0032330	regulation of chondrocyte differentiation(GO:0032330)
0.0	0.1	GO:0034616	response to laminar fluid shear stress(GO:0034616)
0.0	0.1	GO:0060129	thyroid-stimulating hormone-secreting cell differentiation(GO:0060129)
0.0	0.2	GO:0046485	ether lipid metabolic process(GO:0046485)
0.0	0.1	GO:0070141	response to UV-A(GO:0070141)
0.0	0.0	GO:0034776	response to histamine(GO:0034776)
0.0	0.2	GO:1901797	negative regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043518) negative regulation of signal transduction by p53 class mediator(GO:1901797)
0.0	0.1	GO:0042117	monocyte activation(GO:0042117)
0.0	0.1	GO:0008218	bioluminescence(GO:0008218)
0.0	0.2	GO:0000239	pachytene(GO:0000239)
0.0	0.2	GO:0006048	UDP-N-acetylglucosamine biosynthetic process(GO:0006048)
0.0	0.5	GO:0016998	cell wall macromolecule catabolic process(GO:0016998)
0.0	0.1	GO:0043653	mitochondrial fragmentation involved in apoptotic process(GO:0043653)
0.0	0.1	GO:0006927	obsolete transformed cell apoptotic process(GO:0006927)
0.0	0.1	GO:0002023	reduction of food intake in response to dietary excess(GO:0002023)
0.0	0.0	GO:0042637	catagen(GO:0042637)
0.0	0.1	GO:0051024	positive regulation of immunoglobulin secretion(GO:0051024)
0.0	0.1	GO:0046952	ketone body catabolic process(GO:0046952)
0.0	0.1	GO:0050774	negative regulation of dendrite morphogenesis(GO:0050774)
0.0	0.0	GO:0021938	smoothened signaling pathway involved in regulation of cerebellar granule cell precursor cell proliferation(GO:0021938)
0.0	0.1	GO:0055064	cellular chloride ion homeostasis(GO:0030644) chloride ion homeostasis(GO:0055064)
0.0	0.1	GO:0060159	regulation of dopamine receptor signaling pathway(GO:0060159)
0.0	0.1	GO:0061004	pattern specification involved in kidney development(GO:0061004) renal system pattern specification(GO:0072048) pattern specification involved in metanephros development(GO:0072268)
0.0	0.0	GO:0055094	response to lipoprotein particle(GO:0055094)
0.0	0.1	GO:0090026	regulation of monocyte chemotaxis(GO:0090025) positive regulation of monocyte chemotaxis(GO:0090026)
0.0	0.1	GO:0046337	phosphatidylethanolamine biosynthetic process(GO:0006646) phosphatidylethanolamine metabolic process(GO:0046337)
0.0	0.1	GO:0006931	substrate-dependent cell migration, cell attachment to substrate(GO:0006931)
0.0	0.1	GO:0046607	positive regulation of centrosome cycle(GO:0046607)
0.0	0.1	GO:0016266	O-glycan processing(GO:0016266)
0.0	0.1	GO:0010867	positive regulation of triglyceride biosynthetic process(GO:0010867)
0.0	0.1	GO:0006654	phosphatidic acid biosynthetic process(GO:0006654)
0.0	0.2	GO:0009396	folic acid-containing compound biosynthetic process(GO:0009396)
0.0	0.1	GO:0071502	cellular response to temperature stimulus(GO:0071502)
0.0	0.2	GO:0008228	opsonization(GO:0008228)
0.0	0.1	GO:0055089	fatty acid homeostasis(GO:0055089)
0.0	0.1	GO:0071288	cellular response to mercury ion(GO:0071288)
0.0	0.1	GO:0001779	natural killer cell differentiation(GO:0001779)
0.0	0.1	GO:0001996	positive regulation of heart rate by epinephrine-norepinephrine(GO:0001996)
0.0	0.1	GO:0006572	tyrosine catabolic process(GO:0006572)
0.0	0.2	GO:0015871	choline transport(GO:0015871)
0.0	0.2	GO:0042693	muscle cell fate commitment(GO:0042693)
0.0	0.1	GO:0001547	antral ovarian follicle growth(GO:0001547)
0.0	0.1	GO:0021631	optic nerve morphogenesis(GO:0021631)
0.0	0.1	GO:0090162	establishment of epithelial cell polarity(GO:0090162)
0.0	0.1	GO:0008354	germ cell migration(GO:0008354)
0.0	0.0	GO:0060294	regulation of cilium movement(GO:0003352) regulation of cilium beat frequency(GO:0003356) cilium movement involved in cell motility(GO:0060294) regulation of cilium movement involved in cell motility(GO:0060295) regulation of cilium beat frequency involved in ciliary motility(GO:0060296) regulation of cilium-dependent cell motility(GO:1902019)
0.0	0.1	GO:0007598	blood coagulation, extrinsic pathway(GO:0007598)
0.0	0.1	GO:0010761	fibroblast migration(GO:0010761)
0.0	0.1	GO:0032780	negative regulation of ATPase activity(GO:0032780)
0.0	0.0	GO:0060435	bronchiole development(GO:0060435)
0.0	0.0	GO:0002689	negative regulation of leukocyte chemotaxis(GO:0002689)
0.0	0.1	GO:0009189	deoxyribonucleoside diphosphate biosynthetic process(GO:0009189)
0.0	0.0	GO:0010936	negative regulation of macrophage cytokine production(GO:0010936)
0.0	0.1	GO:0006663	platelet activating factor biosynthetic process(GO:0006663)
0.0	0.1	GO:0007095	mitotic G2 DNA damage checkpoint(GO:0007095)
0.0	0.1	GO:0006573	valine metabolic process(GO:0006573)
0.0	0.1	GO:1901976	regulation of cell cycle checkpoint(GO:1901976)
0.0	0.1	GO:0043030	regulation of macrophage activation(GO:0043030)
0.0	0.2	GO:0044341	sodium-dependent phosphate transport(GO:0044341)
0.0	0.1	GO:0001757	somite specification(GO:0001757)
0.0	0.2	GO:0048844	artery morphogenesis(GO:0048844) artery development(GO:0060840)
0.0	0.0	GO:0061302	smooth muscle cell-matrix adhesion(GO:0061302)
0.0	0.1	GO:0010834	obsolete telomere maintenance via telomere shortening(GO:0010834)
0.0	0.2	GO:0007520	syncytium formation(GO:0006949) myoblast fusion(GO:0007520)
0.0	0.0	GO:0046639	negative regulation of alpha-beta T cell differentiation(GO:0046639)
0.0	0.1	GO:0034446	substrate adhesion-dependent cell spreading(GO:0034446)
0.0	0.1	GO:0048702	embryonic neurocranium morphogenesis(GO:0048702)
0.0	0.1	GO:0090136	epithelial cell-cell adhesion(GO:0090136)
0.0	0.1	GO:0048755	branching morphogenesis of a nerve(GO:0048755)
0.0	0.0	GO:0042726	flavin-containing compound metabolic process(GO:0042726)
0.0	0.3	GO:0006195	purine nucleotide catabolic process(GO:0006195)
0.0	0.1	GO:0006477	protein sulfation(GO:0006477)
0.0	0.1	GO:1900078	positive regulation of insulin receptor signaling pathway(GO:0046628) positive regulation of cellular response to insulin stimulus(GO:1900078)
0.0	0.1	GO:0006570	tyrosine metabolic process(GO:0006570)
0.0	0.4	GO:0014032	neural crest cell development(GO:0014032)
0.0	0.2	GO:0050922	negative regulation of chemotaxis(GO:0050922)
0.0	0.1	GO:0043457	regulation of cellular respiration(GO:0043457)
0.0	0.0	GO:2000171	negative regulation of dendrite development(GO:2000171)
0.0	0.2	GO:0007494	midgut development(GO:0007494)
0.0	0.1	GO:0033173	calcineurin-NFAT signaling cascade(GO:0033173)
0.0	0.1	GO:0043268	positive regulation of potassium ion transport(GO:0043268)
0.0	0.1	GO:0060391	positive regulation of SMAD protein import into nucleus(GO:0060391)
0.0	0.1	GO:0071731	response to nitric oxide(GO:0071731)
0.0	0.1	GO:0051877	pigment granule aggregation in cell center(GO:0051877)
0.0	0.4	GO:0010811	positive regulation of cell-substrate adhesion(GO:0010811)
0.0	0.3	GO:0050879	multicellular organismal movement(GO:0050879) musculoskeletal movement(GO:0050881)
0.0	0.0	GO:0046349	amino sugar biosynthetic process(GO:0046349)
0.0	0.2	GO:0046457	prostaglandin biosynthetic process(GO:0001516) prostanoid biosynthetic process(GO:0046457)
0.0	0.0	GO:0048630	skeletal muscle tissue growth(GO:0048630)
0.0	0.1	GO:0072677	eosinophil chemotaxis(GO:0048245) eosinophil migration(GO:0072677)
0.0	0.2	GO:0007528	neuromuscular junction development(GO:0007528)
0.0	0.1	GO:0010799	regulation of peptidyl-threonine phosphorylation(GO:0010799) positive regulation of peptidyl-threonine phosphorylation(GO:0010800)
0.0	0.0	GO:0045992	negative regulation of embryonic development(GO:0045992)
0.0	0.0	GO:0035588	adenosine receptor signaling pathway(GO:0001973) G-protein coupled purinergic receptor signaling pathway(GO:0035588)
0.0	0.0	GO:0070874	negative regulation of glycogen metabolic process(GO:0070874)
0.0	0.1	GO:0015889	cobalamin transport(GO:0015889)
0.0	0.1	GO:0010874	regulation of cholesterol efflux(GO:0010874)
0.0	0.1	GO:0018027	peptidyl-lysine dimethylation(GO:0018027)
0.0	0.1	GO:0048016	inositol phosphate-mediated signaling(GO:0048016)
0.0	0.2	GO:0015701	bicarbonate transport(GO:0015701)
0.0	0.1	GO:0046835	carbohydrate phosphorylation(GO:0046835)
0.0	0.0	GO:0048311	mitochondrion distribution(GO:0048311)
0.0	0.1	GO:0090049	regulation of cell migration involved in sprouting angiogenesis(GO:0090049) regulation of sprouting angiogenesis(GO:1903670)
0.0	0.1	GO:0006452	translational frameshifting(GO:0006452) positive regulation of translational elongation(GO:0045901) positive regulation of translational termination(GO:0045905)
0.0	0.1	GO:0050847	progesterone receptor signaling pathway(GO:0050847)
0.0	0.1	GO:0033962	cytoplasmic mRNA processing body assembly(GO:0033962)
0.0	0.2	GO:0042745	circadian sleep/wake cycle(GO:0042745)
0.0	0.1	GO:0090292	nuclear matrix organization(GO:0043578) nuclear matrix anchoring at nuclear membrane(GO:0090292)
0.0	0.1	GO:0006777	Mo-molybdopterin cofactor biosynthetic process(GO:0006777) Mo-molybdopterin cofactor metabolic process(GO:0019720) molybdopterin cofactor biosynthetic process(GO:0032324) molybdopterin cofactor metabolic process(GO:0043545) prosthetic group metabolic process(GO:0051189)
0.0	0.1	GO:0050930	induction of positive chemotaxis(GO:0050930)
0.0	0.0	GO:0005981	regulation of glycogen catabolic process(GO:0005981)
0.0	0.0	GO:0001560	regulation of cell growth by extracellular stimulus(GO:0001560)
0.0	0.0	GO:0048484	enteric nervous system development(GO:0048484)
0.0	0.0	GO:0033629	negative regulation of cell adhesion mediated by integrin(GO:0033629)
0.0	0.0	GO:0042816	pyridoxine metabolic process(GO:0008614) pyridoxine biosynthetic process(GO:0008615) vitamin B6 metabolic process(GO:0042816) vitamin B6 biosynthetic process(GO:0042819)
0.0	0.0	GO:0007171	activation of transmembrane receptor protein tyrosine kinase activity(GO:0007171)
0.0	0.1	GO:2000400	positive regulation of T cell differentiation in thymus(GO:0033089) positive regulation of thymocyte aggregation(GO:2000400)
0.0	0.0	GO:0097709	connective tissue replacement involved in inflammatory response wound healing(GO:0002248) connective tissue replacement(GO:0097709)
0.0	0.0	GO:0030263	apoptotic chromosome condensation(GO:0030263)
0.0	0.1	GO:0046653	tetrahydrofolate metabolic process(GO:0046653)
0.0	0.0	GO:0019388	galactose catabolic process(GO:0019388)
0.0	0.0	GO:0070098	chemokine-mediated signaling pathway(GO:0070098)
0.0	0.0	GO:0071800	podosome assembly(GO:0071800)
0.0	0.1	GO:0045600	positive regulation of fat cell differentiation(GO:0045600)
0.0	0.1	GO:0070327	thyroid hormone transport(GO:0070327)
0.0	0.0	GO:0001957	intramembranous ossification(GO:0001957) direct ossification(GO:0036072)
0.0	0.1	GO:0001660	fever generation(GO:0001660)
0.0	0.0	GO:0100012	regulation of heart induction(GO:0090381) regulation of heart induction by canonical Wnt signaling pathway(GO:0100012)
0.0	0.1	GO:1901985	positive regulation of histone acetylation(GO:0035066) positive regulation of protein acetylation(GO:1901985) positive regulation of peptidyl-lysine acetylation(GO:2000758)
0.0	0.0	GO:0006166	purine ribonucleoside salvage(GO:0006166)
0.0	0.1	GO:0072383	plus-end-directed vesicle transport along microtubule(GO:0072383) plus-end-directed organelle transport along microtubule(GO:0072386)
0.0	0.1	GO:0006546	glycine catabolic process(GO:0006546)
0.0	0.0	GO:0060710	chorio-allantoic fusion(GO:0060710)
0.0	0.2	GO:0032964	collagen biosynthetic process(GO:0032964)
0.0	0.1	GO:0045075	interleukin-12 biosynthetic process(GO:0042090) regulation of interleukin-12 biosynthetic process(GO:0045075)
0.0	0.0	GO:2001021	negative regulation of response to DNA damage stimulus(GO:2001021)
0.0	0.0	GO:0021955	central nervous system neuron axonogenesis(GO:0021955)
0.0	0.0	GO:1902224	ketone body metabolic process(GO:1902224)
0.0	0.0	GO:0006210	pyrimidine nucleobase catabolic process(GO:0006208) thymine catabolic process(GO:0006210) thymine metabolic process(GO:0019859) nucleobase catabolic process(GO:0046113)
0.0	0.0	GO:0060206	estrous cycle phase(GO:0060206)
0.0	0.0	GO:0010866	regulation of triglyceride biosynthetic process(GO:0010866)
0.0	0.0	GO:0007000	nucleolus organization(GO:0007000)
0.0	0.0	GO:0051541	elastin metabolic process(GO:0051541)
0.0	0.0	GO:0051151	negative regulation of smooth muscle cell differentiation(GO:0051151)
0.0	0.0	GO:0048319	axial mesoderm morphogenesis(GO:0048319)
0.0	0.0	GO:0060662	tube lumen cavitation(GO:0060605) salivary gland cavitation(GO:0060662)
0.0	0.0	GO:0031645	negative regulation of neurological system process(GO:0031645) negative regulation of transmission of nerve impulse(GO:0051970)
0.0	0.1	GO:0006590	thyroid hormone generation(GO:0006590)
0.0	0.0	GO:0021869	forebrain ventricular zone progenitor cell division(GO:0021869)
0.0	0.0	GO:0045650	negative regulation of macrophage differentiation(GO:0045650)
0.0	0.0	GO:0035987	endodermal cell fate commitment(GO:0001711) endodermal cell fate specification(GO:0001714) regulation of gastrulation(GO:0010470) endodermal cell differentiation(GO:0035987) regulation of endodermal cell fate specification(GO:0042663) regulation of endodermal cell differentiation(GO:1903224)
0.0	0.2	GO:0045104	intermediate filament cytoskeleton organization(GO:0045104)
0.0	0.0	GO:0051818	disruption of cells of other organism involved in symbiotic interaction(GO:0051818) killing of cells in other organism involved in symbiotic interaction(GO:0051883)
0.0	0.0	GO:0060004	reflex(GO:0060004)
0.0	0.1	GO:0060134	prepulse inhibition(GO:0060134)
0.0	0.0	GO:0031117	positive regulation of microtubule depolymerization(GO:0031117)
0.0	0.1	GO:0061462	protein targeting to lysosome(GO:0006622) protein targeting to vacuole(GO:0006623) protein localization to lysosome(GO:0061462) protein localization to vacuole(GO:0072665) establishment of protein localization to vacuole(GO:0072666)
0.0	0.0	GO:0032785	negative regulation of DNA-templated transcription, elongation(GO:0032785) negative regulation of transcription elongation from RNA polymerase II promoter(GO:0034244)
0.0	0.0	GO:0030573	bile acid catabolic process(GO:0030573)
0.0	0.1	GO:0031290	retinal ganglion cell axon guidance(GO:0031290)
0.0	0.0	GO:0051176	positive regulation of sulfur metabolic process(GO:0051176)
0.0	0.0	GO:0090075	relaxation of muscle(GO:0090075)
0.0	0.0	GO:0001831	trophectodermal cellular morphogenesis(GO:0001831)
0.0	0.0	GO:0009261	ribonucleotide catabolic process(GO:0009261)
0.0	0.0	GO:0014821	phasic smooth muscle contraction(GO:0014821)
0.0	0.0	GO:0045162	clustering of voltage-gated sodium channels(GO:0045162)
0.0	0.0	GO:0070857	regulation of bile acid biosynthetic process(GO:0070857) regulation of bile acid metabolic process(GO:1904251)
0.0	0.0	GO:0046121	deoxyribonucleoside catabolic process(GO:0046121)
0.0	0.0	GO:0006525	arginine metabolic process(GO:0006525)
0.0	0.0	GO:0032525	somite rostral/caudal axis specification(GO:0032525)
0.0	0.0	GO:0048853	forebrain morphogenesis(GO:0048853)
0.0	0.1	GO:0006108	malate metabolic process(GO:0006108)
0.0	0.1	GO:0018298	protein-chromophore linkage(GO:0018298)
0.0	0.2	GO:0007214	gamma-aminobutyric acid signaling pathway(GO:0007214)
0.0	0.0	GO:0048861	leukemia inhibitory factor signaling pathway(GO:0048861)
0.0	0.1	GO:0046541	saliva secretion(GO:0046541)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	0.5	GO:0005589	collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.1	0.4	GO:0030934	anchoring collagen complex(GO:0030934)
0.1	0.1	GO:0071664	catenin-TCF7L2 complex(GO:0071664)
0.1	0.7	GO:0098645	network-forming collagen trimer(GO:0098642) collagen network(GO:0098645)
0.1	0.7	GO:0005614	interstitial matrix(GO:0005614)
0.1	0.1	GO:0098651	basement membrane collagen trimer(GO:0098651)
0.1	0.2	GO:0005588	collagen type V trimer(GO:0005588)
0.1	0.5	GO:0005916	fascia adherens(GO:0005916)
0.1	0.2	GO:0005862	muscle thin filament tropomyosin(GO:0005862)
0.1	0.2	GO:0071438	invadopodium membrane(GO:0071438)
0.1	0.2	GO:0016327	apicolateral plasma membrane(GO:0016327)
0.1	0.1	GO:0071437	invadopodium(GO:0071437)
0.0	0.2	GO:0030056	hemidesmosome(GO:0030056)
0.0	0.2	GO:0005954	calcium- and calmodulin-dependent protein kinase complex(GO:0005954)
0.0	0.1	GO:0043260	laminin-11 complex(GO:0043260)
0.0	0.2	GO:0033268	node of Ranvier(GO:0033268)
0.0	0.2	GO:0031232	extrinsic component of external side of plasma membrane(GO:0031232)
0.0	0.2	GO:0030870	Mre11 complex(GO:0030870)
0.0	0.2	GO:0001527	microfibril(GO:0001527)
0.0	0.2	GO:0031588	nucleotide-activated protein kinase complex(GO:0031588)
0.0	0.2	GO:0005915	zonula adherens(GO:0005915)
0.0	0.1	GO:0000015	phosphopyruvate hydratase complex(GO:0000015)
0.0	0.1	GO:0005863	striated muscle myosin thick filament(GO:0005863)
0.0	0.6	GO:0005581	collagen trimer(GO:0005581)
0.0	0.1	GO:0043230	extracellular organelle(GO:0043230)
0.0	0.2	GO:0017146	NMDA selective glutamate receptor complex(GO:0017146)
0.0	0.1	GO:0036454	insulin-like growth factor binding protein complex(GO:0016942) growth factor complex(GO:0036454)
0.0	0.2	GO:0033162	melanosome membrane(GO:0033162) chitosome(GO:0045009)
0.0	0.2	GO:0070531	BRCA1-A complex(GO:0070531)
0.0	0.2	GO:0030673	axolemma(GO:0030673)
0.0	0.2	GO:0043256	laminin complex(GO:0043256)
0.0	0.2	GO:0005577	fibrinogen complex(GO:0005577)
0.0	0.2	GO:0031092	platelet alpha granule membrane(GO:0031092)
0.0	0.2	GO:0042598	obsolete vesicular fraction(GO:0042598)
0.0	0.1	GO:0033150	cytoskeletal calyx(GO:0033150)
0.0	0.9	GO:0005884	actin filament(GO:0005884)
0.0	0.1	GO:0032045	guanyl-nucleotide exchange factor complex(GO:0032045)
0.0	0.1	GO:0031616	spindle pole centrosome(GO:0031616)
0.0	0.1	GO:0046696	lipopolysaccharide receptor complex(GO:0046696)
0.0	0.0	GO:0045334	clathrin-coated endocytic vesicle(GO:0045334)
0.0	0.4	GO:0005811	lipid particle(GO:0005811)
0.0	0.2	GO:0009925	basal plasma membrane(GO:0009925)
0.0	0.9	GO:0044309	neuron spine(GO:0044309)
0.0	0.1	GO:0030288	outer membrane-bounded periplasmic space(GO:0030288) periplasmic space(GO:0042597)
0.0	0.3	GO:0030132	clathrin coat of coated pit(GO:0030132)
0.0	0.2	GO:0031233	intrinsic component of external side of plasma membrane(GO:0031233)
0.0	0.2	GO:0034464	BBSome(GO:0034464)
0.0	0.0	GO:0043083	synaptic cleft(GO:0043083)
0.0	0.1	GO:0005827	polar microtubule(GO:0005827)
0.0	0.1	GO:0045254	pyruvate dehydrogenase complex(GO:0045254)
0.0	0.2	GO:0030315	T-tubule(GO:0030315)
0.0	0.1	GO:0034673	inhibin-betaglycan-ActRII complex(GO:0034673)
0.0	0.1	GO:0031512	motile primary cilium(GO:0031512)
0.0	0.1	GO:0030127	COPII vesicle coat(GO:0030127)
0.0	1.7	GO:0030016	myofibril(GO:0030016)
0.0	0.0	GO:0005899	insulin receptor complex(GO:0005899)
0.0	0.1	GO:0005697	telomerase holoenzyme complex(GO:0005697)
0.0	0.1	GO:0016012	dystroglycan complex(GO:0016011) sarcoglycan complex(GO:0016012)
0.0	0.0	GO:0045323	interleukin-1 receptor complex(GO:0045323)
0.0	0.1	GO:0031265	CD95 death-inducing signaling complex(GO:0031265)
0.0	0.6	GO:0005604	basement membrane(GO:0005604)
0.0	0.0	GO:0043205	fibril(GO:0043205)
0.0	0.0	GO:0070044	synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044)
0.0	0.0	GO:0070852	cell body fiber(GO:0070852)
0.0	0.0	GO:0016939	kinesin II complex(GO:0016939)
0.0	0.0	GO:0005900	oncostatin-M receptor complex(GO:0005900)
0.0	0.1	GO:0090665	dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.0	0.0	GO:0009331	glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.0	0.0	GO:0000137	Golgi cis cisterna(GO:0000137)
0.0	0.1	GO:0043198	dendritic shaft(GO:0043198)
0.0	0.0	GO:0030669	clathrin-coated endocytic vesicle membrane(GO:0030669)
0.0	2.2	GO:0005578	proteinaceous extracellular matrix(GO:0005578)
0.0	0.3	GO:0005905	clathrin-coated pit(GO:0005905)
0.0	0.1	GO:0031307	integral component of mitochondrial outer membrane(GO:0031307)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	0.5	GO:0051371	muscle alpha-actinin binding(GO:0051371)
0.2	0.5	GO:0004117	calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117)
0.1	0.4	GO:0001099	basal transcription machinery binding(GO:0001098) basal RNA polymerase II transcription machinery binding(GO:0001099)
0.1	0.3	GO:0004687	myosin light chain kinase activity(GO:0004687)
0.1	0.4	GO:0042805	actinin binding(GO:0042805)
0.1	0.2	GO:0033743	peptide-methionine (R)-S-oxide reductase activity(GO:0033743)
0.1	0.2	GO:0003836	beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.1	0.4	GO:0030274	LIM domain binding(GO:0030274)
0.1	0.2	GO:0045545	syndecan binding(GO:0045545)
0.1	0.3	GO:0004616	phosphogluconate dehydrogenase (decarboxylating) activity(GO:0004616)
0.1	0.3	GO:0016724	ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.1	0.5	GO:0017166	vinculin binding(GO:0017166)
0.1	0.4	GO:0008253	5'-nucleotidase activity(GO:0008253)
0.1	0.5	GO:0045294	alpha-catenin binding(GO:0045294)
0.1	0.2	GO:0004720	protein-lysine 6-oxidase activity(GO:0004720)
0.1	0.3	GO:0008510	sodium:bicarbonate symporter activity(GO:0008510)
0.1	0.2	GO:0050501	hyaluronan synthase activity(GO:0050501)
0.1	0.2	GO:0070052	collagen V binding(GO:0070052)
0.1	0.4	GO:0051636	obsolete Gram-negative bacterial cell surface binding(GO:0051636)
0.1	0.2	GO:0004597	peptide-aspartate beta-dioxygenase activity(GO:0004597)
0.1	0.1	GO:0070097	delta-catenin binding(GO:0070097)
0.1	0.2	GO:0005315	inorganic phosphate transmembrane transporter activity(GO:0005315)
0.1	0.2	GO:0004103	choline kinase activity(GO:0004103)
0.1	0.2	GO:0000268	peroxisome targeting sequence binding(GO:0000268)
0.1	0.4	GO:0017154	semaphorin receptor activity(GO:0017154)
0.1	0.2	GO:0008475	procollagen-lysine 5-dioxygenase activity(GO:0008475)
0.1	0.3	GO:0070696	transmembrane receptor protein serine/threonine kinase binding(GO:0070696)
0.1	0.2	GO:0004111	creatine kinase activity(GO:0004111)
0.1	0.1	GO:0043559	insulin binding(GO:0043559)
0.1	0.7	GO:0005523	tropomyosin binding(GO:0005523)
0.0	1.0	GO:0008093	cytoskeletal adaptor activity(GO:0008093)
0.0	0.1	GO:0005006	epidermal growth factor-activated receptor activity(GO:0005006)
0.0	0.4	GO:0001968	fibronectin binding(GO:0001968)
0.0	0.3	GO:0030020	extracellular matrix structural constituent conferring tensile strength(GO:0030020)
0.0	0.2	GO:0005172	vascular endothelial growth factor receptor binding(GO:0005172)
0.0	0.1	GO:0015204	urea transmembrane transporter activity(GO:0015204)
0.0	0.2	GO:0047238	glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity(GO:0047238)
0.0	0.1	GO:0022889	L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.0	0.2	GO:0008607	phosphorylase kinase regulator activity(GO:0008607)
0.0	0.1	GO:0016882	cyclo-ligase activity(GO:0016882)
0.0	0.2	GO:0004082	bisphosphoglycerate mutase activity(GO:0004082) bisphosphoglycerate 2-phosphatase activity(GO:0004083) phosphoglycerate mutase activity(GO:0004619)
0.0	0.1	GO:0004924	oncostatin-M receptor activity(GO:0004924)
0.0	0.1	GO:0042808	obsolete neuronal Cdc2-like kinase binding(GO:0042808)
0.0	0.2	GO:0004945	angiotensin receptor activity(GO:0001595) angiotensin type II receptor activity(GO:0004945)
0.0	0.1	GO:0070548	L-glutamine aminotransferase activity(GO:0070548)
0.0	1.3	GO:0005518	collagen binding(GO:0005518)
0.0	0.1	GO:0004167	dopachrome isomerase activity(GO:0004167)
0.0	0.1	GO:0005134	interleukin-2 receptor binding(GO:0005134)
0.0	0.3	GO:0005123	death receptor binding(GO:0005123)
0.0	0.1	GO:0017159	pantetheine hydrolase activity(GO:0017159)
0.0	0.1	GO:0004157	dihydropyrimidinase activity(GO:0004157)
0.0	0.2	GO:0015220	choline transmembrane transporter activity(GO:0015220)
0.0	0.2	GO:0030346	protein phosphatase 2B binding(GO:0030346)
0.0	0.1	GO:0005010	insulin-like growth factor-activated receptor activity(GO:0005010)
0.0	0.2	GO:0004551	nucleotide diphosphatase activity(GO:0004551)
0.0	0.1	GO:0032450	maltose alpha-glucosidase activity(GO:0032450)
0.0	0.2	GO:0022821	potassium ion antiporter activity(GO:0022821)
0.0	0.1	GO:0030354	melanin-concentrating hormone activity(GO:0030354)
0.0	0.1	GO:0008401	retinoic acid 4-hydroxylase activity(GO:0008401)
0.0	0.2	GO:0005110	frizzled-2 binding(GO:0005110)
0.0	0.3	GO:0008191	metalloendopeptidase inhibitor activity(GO:0008191)
0.0	0.1	GO:0043125	ErbB-3 class receptor binding(GO:0043125)
0.0	0.1	GO:0016623	oxidoreductase activity, acting on the aldehyde or oxo group of donors, oxygen as acceptor(GO:0016623)
0.0	0.1	GO:0016847	1-aminocyclopropane-1-carboxylate synthase activity(GO:0016847)
0.0	0.3	GO:0043498	obsolete cell surface binding(GO:0043498)
0.0	0.1	GO:0004800	thyroxine 5'-deiodinase activity(GO:0004800)
0.0	0.1	GO:0017162	aryl hydrocarbon receptor binding(GO:0017162)
0.0	0.2	GO:0046790	virion binding(GO:0046790)
0.0	1.7	GO:0005201	extracellular matrix structural constituent(GO:0005201)
0.0	0.0	GO:0019215	intermediate filament binding(GO:0019215)
0.0	0.1	GO:0001609	G-protein coupled adenosine receptor activity(GO:0001609)
0.0	0.5	GO:0005520	insulin-like growth factor binding(GO:0005520)
0.0	0.1	GO:0004948	calcitonin receptor activity(GO:0004948)
0.0	0.1	GO:0047023	androsterone dehydrogenase activity(GO:0047023)
0.0	0.1	GO:0048495	Roundabout binding(GO:0048495)
0.0	0.2	GO:0016813	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
0.0	0.1	GO:0034584	piRNA binding(GO:0034584)
0.0	0.1	GO:0017112	Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0	0.1	GO:0005111	type 2 fibroblast growth factor receptor binding(GO:0005111)
0.0	0.0	GO:0004992	platelet activating factor receptor activity(GO:0004992)
0.0	0.1	GO:0004969	histamine receptor activity(GO:0004969)
0.0	0.3	GO:0004012	phospholipid-translocating ATPase activity(GO:0004012)
0.0	0.3	GO:0035035	histone acetyltransferase binding(GO:0035035)
0.0	0.2	GO:0017075	syntaxin-1 binding(GO:0017075)
0.0	0.1	GO:0008574	ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574) ATP-dependent microtubule motor activity(GO:1990939)
0.0	0.2	GO:0005522	profilin binding(GO:0005522)
0.0	0.0	GO:0005176	ErbB-2 class receptor binding(GO:0005176)
0.0	0.1	GO:0052650	NADP-retinol dehydrogenase activity(GO:0052650)
0.0	0.1	GO:0030492	hemoglobin binding(GO:0030492)
0.0	0.1	GO:0004470	malic enzyme activity(GO:0004470)
0.0	0.1	GO:0010314	phosphatidylinositol-5-phosphate binding(GO:0010314)
0.0	0.1	GO:0030151	molybdenum ion binding(GO:0030151)
0.0	0.1	GO:0005007	fibroblast growth factor-activated receptor activity(GO:0005007)
0.0	0.1	GO:0000293	ferric-chelate reductase activity(GO:0000293)
0.0	0.1	GO:0008332	low voltage-gated calcium channel activity(GO:0008332)
0.0	0.1	GO:0045499	chemorepellent activity(GO:0045499)
0.0	0.1	GO:0004965	G-protein coupled GABA receptor activity(GO:0004965)
0.0	0.2	GO:0005031	tumor necrosis factor-activated receptor activity(GO:0005031)
0.0	0.1	GO:0004332	fructose-bisphosphate aldolase activity(GO:0004332)
0.0	0.0	GO:0016509	long-chain-3-hydroxyacyl-CoA dehydrogenase activity(GO:0016509)
0.0	0.1	GO:0008898	S-adenosylmethionine-homocysteine S-methyltransferase activity(GO:0008898)
0.0	0.0	GO:0034416	bisphosphoglycerate phosphatase activity(GO:0034416)
0.0	0.1	GO:0001875	lipopolysaccharide receptor activity(GO:0001875)
0.0	0.1	GO:0004047	aminomethyltransferase activity(GO:0004047)
0.0	0.1	GO:0005350	pyrimidine nucleobase transmembrane transporter activity(GO:0005350)
0.0	0.1	GO:0008174	mRNA methyltransferase activity(GO:0008174)
0.0	0.1	GO:0015016	[heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
0.0	0.1	GO:0008179	adenylate cyclase binding(GO:0008179)
0.0	0.1	GO:0004634	phosphopyruvate hydratase activity(GO:0004634)
0.0	0.1	GO:0030332	cyclin binding(GO:0030332)
0.0	0.1	GO:0004833	tryptophan 2,3-dioxygenase activity(GO:0004833)
0.0	0.3	GO:0008603	cAMP-dependent protein kinase regulator activity(GO:0008603)
0.0	0.1	GO:0033130	acetylcholine receptor binding(GO:0033130)
0.0	0.4	GO:0004181	metallocarboxypeptidase activity(GO:0004181)
0.0	0.0	GO:0004461	lactose synthase activity(GO:0004461)
0.0	0.0	GO:0008061	chitin binding(GO:0008061)
0.0	0.1	GO:0005499	vitamin D binding(GO:0005499)
0.0	0.0	GO:0042289	MHC class II protein binding(GO:0042289)
0.0	0.0	GO:0004792	thiosulfate sulfurtransferase activity(GO:0004792)
0.0	0.1	GO:0031210	phosphatidylcholine binding(GO:0031210)
0.0	0.1	GO:0008889	glycerophosphodiester phosphodiesterase activity(GO:0008889)
0.0	0.0	GO:0003829	beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity(GO:0003829)
0.0	0.1	GO:0001871	pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.0	0.0	GO:0033765	steroid dehydrogenase activity, acting on the CH-CH group of donors(GO:0033765)
0.0	0.1	GO:0035251	UDP-glucosyltransferase activity(GO:0035251)
0.0	0.1	GO:0051635	obsolete bacterial cell surface binding(GO:0051635)
0.0	0.2	GO:0008395	steroid hydroxylase activity(GO:0008395)
0.0	0.1	GO:0048027	mRNA 5'-UTR binding(GO:0048027)
0.0	0.1	GO:0004656	procollagen-proline 4-dioxygenase activity(GO:0004656) peptidyl-proline 4-dioxygenase activity(GO:0031545)
0.0	0.3	GO:0017147	Wnt-protein binding(GO:0017147)
0.0	0.0	GO:0032296	ribonuclease III activity(GO:0004525) double-stranded RNA-specific ribonuclease activity(GO:0032296)
0.0	0.0	GO:0004516	nicotinate phosphoribosyltransferase activity(GO:0004516)
0.0	0.0	GO:0070273	phosphatidylinositol-4-phosphate binding(GO:0070273)
0.0	0.1	GO:0008195	phosphatidate phosphatase activity(GO:0008195)
0.0	0.1	GO:0042285	UDP-xylosyltransferase activity(GO:0035252) xylosyltransferase activity(GO:0042285)
0.0	0.1	GO:0004035	alkaline phosphatase activity(GO:0004035)
0.0	0.2	GO:0043015	gamma-tubulin binding(GO:0043015)
0.0	0.1	GO:0047429	nucleoside-triphosphate diphosphatase activity(GO:0047429)
0.0	0.0	GO:0015106	bicarbonate transmembrane transporter activity(GO:0015106)
0.0	0.1	GO:0003708	retinoic acid receptor activity(GO:0003708)
0.0	0.1	GO:0015211	purine nucleoside transmembrane transporter activity(GO:0015211)
0.0	0.0	GO:0004500	dopamine beta-monooxygenase activity(GO:0004500)
0.0	0.1	GO:0051378	serotonin binding(GO:0051378)
0.0	0.0	GO:0004738	pyruvate dehydrogenase activity(GO:0004738) pyruvate dehydrogenase (acetyl-transferring) activity(GO:0004739)
0.0	0.0	GO:0005222	intracellular cAMP activated cation channel activity(GO:0005222)
0.0	0.1	GO:0008641	small protein activating enzyme activity(GO:0008641)
0.0	0.0	GO:0004367	glycerol-3-phosphate dehydrogenase [NAD+] activity(GO:0004367)
0.0	0.0	GO:0003896	DNA primase activity(GO:0003896)
0.0	0.0	GO:0019834	phospholipase A2 inhibitor activity(GO:0019834)
0.0	0.0	GO:0034056	estrogen response element binding(GO:0034056)
0.0	0.0	GO:0001591	dopamine neurotransmitter receptor activity, coupled via Gi/Go(GO:0001591)
0.0	0.3	GO:0004364	glutathione transferase activity(GO:0004364)
0.0	0.2	GO:0005546	phosphatidylinositol-4,5-bisphosphate binding(GO:0005546)
0.0	0.0	GO:0005534	galactose binding(GO:0005534)
0.0	0.1	GO:0003796	lysozyme activity(GO:0003796)
0.0	0.0	GO:0004967	glucagon receptor activity(GO:0004967)
0.0	0.0	GO:0005294	neutral L-amino acid secondary active transmembrane transporter activity(GO:0005294)
0.0	0.1	GO:0005452	inorganic anion exchanger activity(GO:0005452)
0.0	0.1	GO:0005104	fibroblast growth factor receptor binding(GO:0005104)
0.0	0.0	GO:0004307	ethanolaminephosphotransferase activity(GO:0004307)
0.0	0.1	GO:0004791	thioredoxin-disulfide reductase activity(GO:0004791)
0.0	0.1	GO:0051879	Hsp90 protein binding(GO:0051879)
0.0	0.0	GO:0043495	protein anchor(GO:0043495)
0.0	0.0	GO:0015349	thyroid hormone transmembrane transporter activity(GO:0015349)
0.0	0.1	GO:0004982	N-formyl peptide receptor activity(GO:0004982)
0.0	0.0	GO:0004340	glucokinase activity(GO:0004340)
0.0	0.1	GO:0034235	GPI anchor binding(GO:0034235)
0.0	0.0	GO:0004995	tachykinin receptor activity(GO:0004995)
0.0	0.0	GO:0004045	aminoacyl-tRNA hydrolase activity(GO:0004045)
0.0	0.0	GO:0034711	inhibin binding(GO:0034711)
0.0	0.1	GO:0001517	N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517)
0.0	0.0	GO:0016941	natriuretic peptide receptor activity(GO:0016941)
0.0	0.1	GO:0005521	lamin binding(GO:0005521)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	2.3	NABA COLLAGENS	Genes encoding collagen proteins
0.0	0.4	PID VEGF VEGFR PATHWAY	VEGF and VEGFR signaling network
0.0	0.6	PID SYNDECAN 3 PATHWAY	Syndecan-3-mediated signaling events
0.0	0.8	PID INTEGRIN A9B1 PATHWAY	Alpha9 beta1 integrin signaling events
0.0	0.9	NABA PROTEOGLYCANS	Genes encoding proteoglycans
0.0	0.0	PID ECADHERIN KERATINOCYTE PATHWAY	E-cadherin signaling in keratinocytes
0.0	0.1	PID PI3K PLC TRK PATHWAY	Trk receptor signaling mediated by PI3K and PLC-gamma
0.0	0.1	PID PS1 PATHWAY	Presenilin action in Notch and Wnt signaling
0.0	0.7	PID INTEGRIN1 PATHWAY	Beta1 integrin cell surface interactions
0.0	0.0	SIG PIP3 SIGNALING IN B LYMPHOCYTES	Genes related to PIP3 signaling in B lymphocytes
0.0	0.3	PID ARF 3PATHWAY	Arf1 pathway
0.0	0.2	PID CDC42 REG PATHWAY	Regulation of CDC42 activity
0.0	0.1	PID INTEGRIN5 PATHWAY	Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.0	0.0	PID TXA2PATHWAY	Thromboxane A2 receptor signaling
0.0	0.0	PID TCR RAS PATHWAY	Ras signaling in the CD4+ TCR pathway
0.0	0.0	PID PDGFRA PATHWAY	PDGFR-alpha signaling pathway
0.0	0.5	PID ECADHERIN STABILIZATION PATHWAY	Stabilization and expansion of the E-cadherin adherens junction
0.0	1.9	NABA ECM GLYCOPROTEINS	Genes encoding structural ECM glycoproteins
0.0	0.1	PID LYSOPHOSPHOLIPID PATHWAY	LPA receptor mediated events
0.0	0.0	PID TCR JNK PATHWAY	JNK signaling in the CD4+ TCR pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.1	REACTOME DAG AND IP3 SIGNALING	Genes involved in DAG and IP3 signaling
0.1	0.1	REACTOME PEPTIDE HORMONE BIOSYNTHESIS	Genes involved in Peptide hormone biosynthesis
0.1	1.0	REACTOME CRMPS IN SEMA3A SIGNALING	Genes involved in CRMPs in Sema3A signaling
0.1	1.5	REACTOME SMOOTH MUSCLE CONTRACTION	Genes involved in Smooth Muscle Contraction
0.1	0.5	REACTOME GAP JUNCTION DEGRADATION	Genes involved in Gap junction degradation
0.0	0.4	REACTOME VEGF LIGAND RECEPTOR INTERACTIONS	Genes involved in VEGF ligand-receptor interactions
0.0	0.0	REACTOME ARMS MEDIATED ACTIVATION	Genes involved in ARMS-mediated activation
0.0	2.2	REACTOME COLLAGEN FORMATION	Genes involved in Collagen formation
0.0	0.0	REACTOME DESTABILIZATION OF MRNA BY BRF1	Genes involved in Destabilization of mRNA by Butyrate Response Factor 1 (BRF1)
0.0	0.3	REACTOME PURINE CATABOLISM	Genes involved in Purine catabolism
0.0	0.0	REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION	Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.0	0.1	REACTOME FGFR2C LIGAND BINDING AND ACTIVATION	Genes involved in FGFR2c ligand binding and activation
0.0	0.7	REACTOME MYOGENESIS	Genes involved in Myogenesis
0.0	0.1	REACTOME ACTIVATED POINT MUTANTS OF FGFR2	Genes involved in Activated point mutants of FGFR2
0.0	0.4	REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS	Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0	0.1	REACTOME ADP SIGNALLING THROUGH P2RY12	Genes involved in ADP signalling through P2Y purinoceptor 12
0.0	0.0	REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA	Genes involved in Circadian Repression of Expression by REV-ERBA
0.0	0.3	REACTOME HYALURONAN METABOLISM	Genes involved in Hyaluronan metabolism
0.0	0.0	REACTOME RNA POL I PROMOTER OPENING	Genes involved in RNA Polymerase I Promoter Opening
0.0	0.5	REACTOME AMINE COMPOUND SLC TRANSPORTERS	Genes involved in Amine compound SLC transporters
0.0	0.0	REACTOME FGFR4 LIGAND BINDING AND ACTIVATION	Genes involved in FGFR4 ligand binding and activation
0.0	0.2	REACTOME SIGNALING BY ACTIVATED POINT MUTANTS OF FGFR1	Genes involved in Signaling by activated point mutants of FGFR1
0.0	0.2	REACTOME SYNTHESIS OF PE	Genes involved in Synthesis of PE
0.0	0.2	REACTOME GLYCOPROTEIN HORMONES	Genes involved in Glycoprotein hormones
0.0	0.4	REACTOME A TETRASACCHARIDE LINKER SEQUENCE IS REQUIRED FOR GAG SYNTHESIS	Genes involved in A tetrasaccharide linker sequence is required for GAG synthesis
0.0	0.1	REACTOME HORMONE LIGAND BINDING RECEPTORS	Genes involved in Hormone ligand-binding receptors
0.0	0.1	REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS	Genes involved in Ionotropic activity of Kainate Receptors
0.0	0.1	REACTOME KERATAN SULFATE DEGRADATION	Genes involved in Keratan sulfate degradation
0.0	0.2	REACTOME SEROTONIN RECEPTORS	Genes involved in Serotonin receptors
0.0	0.2	REACTOME ENDOGENOUS STEROLS	Genes involved in Endogenous sterols
0.0	0.1	REACTOME SIGNALING BY CONSTITUTIVELY ACTIVE EGFR	Genes involved in Signaling by constitutively active EGFR
0.0	0.2	REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS	Genes involved in Homologous recombination repair of replication-independent double-strand breaks