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ENCODE: H3K4me1 ChIP-Seq of primary human cells
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CREMA is a free online tool that recognizes most important transcription factors that change the chromatin state across different samples.

Results for SOX21

Z-value: 0.99

Motif logo

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Transcription factors associated with SOX21

Gene Symbol Gene ID Gene Info
SOX21
ENSG00000125285.4 SOX21

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE Gene Distance Association probability Pearson corr. coef. P-value Plot
SOX21chr13_95364921_953651886650.733856-0.826.9e-03Click!
SOX21chr13_95360396_9536063038760.244612-0.732.5e-02Click!
SOX21chr13_95365226_953653779120.618457-0.703.6e-02Click!
SOX21chr13_95359832_9536010944190.233546-0.665.1e-02Click!
SOX21chr13_95359323_9535951049730.225187-0.655.8e-02Click!

Activity of the SOX21 motif across conditions

Conditions sorted by the z-value of the SOX21 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE) Target Score Top associated gene Gene Info Distance of CRE to TSS CRE/Gene association probability
chr11_63638814_63639520 1.54 MARK2
 MAP/microtubule affinity-regulating kinase 2
 2419
 0.21
chr5_33011273_33011424 0.40 AC026703.1
222403
 0.02
chr7_28904897_28905048 0.39 CREB5
 cAMP responsive element binding protein 5
 55946
 0.15
chr7_157182751_157183382 0.38 DNAJB6
 DnaJ (Hsp40) homolog, subfamily B, member 6
 50551
 0.15
chr6_23175946_23176097 0.36 ENSG00000207394
 .
 50706
 0.2
chr10_50390146_50390361 0.33 C10orf128
 chromosome 10 open reading frame 128
 6104
 0.2
chr1_41402984_41403135 0.33 CTPS1
 CTP synthase 1
 41948
 0.14
chr13_42422886_42423037 0.31 ENSG00000241406
 .
 41148
 0.17
chr17_15151290_15151441 0.31 ENSG00000265110
 .
 3648
 0.18
chr7_1128803_1128954 0.31 GPER1
 G protein-coupled estrogen receptor 1
 1155
 0.33
chrX_41436872_41437023 0.31 ENSG00000212207
 .
 6665
 0.19
chr5_54292673_54292824 0.30 ESM1
 endothelial cell-specific molecule 1
 11257
 0.15
chr7_137485736_137485887 0.30 DGKI
 diacylglycerol kinase, iota
 45471
 0.18
chr4_26379019_26379170 0.30 RBPJ
 recombination signal binding protein for immunoglobulin kappa J region
 14942
 0.29
chr11_35268427_35268939 0.30 SLC1A2
 solute carrier family 1 (glial high affinity glutamate transporter), member 2
 18609
 0.14
chr1_168645642_168645793 0.29 DPT
 dermatopontin
 52785
 0.14
chr1_185390714_185391145 0.29 ENSG00000252407
 .
 12447
 0.26
chr11_33728608_33728759 0.28 C11orf91
 chromosome 11 open reading frame 91
 6336
 0.16
chr9_127958620_127958997 0.28 RABEPK
 Rab9 effector protein with kelch motifs
 4013
 0.19
chr12_26147767_26147918 0.28 RASSF8
 Ras association (RalGDS/AF-6) domain family (N-terminal) member 8
 95
 0.98
chr5_114732364_114732515 0.28 CCDC112
 coiled-coil domain containing 112
 99911
 0.07
chrX_9916732_9916883 0.28 AC002365.1
 Homo sapiens uncharacterized LOC100288814 (LOC100288814), mRNA.
 18585
 0.18
chr1_115870179_115870464 0.28 NGF
 nerve growth factor (beta polypeptide)
 10536
 0.26
chr1_207498954_207499162 0.27 CD55
 CD55 molecule, decay accelerating factor for complement (Cromer blood group)
 3922
 0.32
chr11_46352086_46352730 0.27 DGKZ
 diacylglycerol kinase, zeta
 2047
 0.27
chr8_100104257_100104408 0.27 CTD-2340D6.2
1956
 0.37
chr6_20497430_20497581 0.27 ENSG00000201683
 .
 2901
 0.25
chr13_74701587_74701980 0.27 KLF12
 Kruppel-like factor 12
 6611
 0.34
chr14_35406723_35406874 0.27 ENSG00000199980
 .
 4049
 0.21
chr1_198711011_198711162 0.27 RP11-553K8.5
74896
 0.11
chr2_163222644_163222795 0.27 GCA
 grancalcin, EF-hand calcium binding protein
 9771
 0.25
chr1_156172141_156172292 0.26 SLC25A44
 solute carrier family 25, member 44
 8309
 0.09
chr6_106695084_106695357 0.26 ENSG00000244710
 .
 36366
 0.16
chr4_17191268_17191419 0.26 ENSG00000206780
 .
 131162
 0.05
chr5_98269675_98269959 0.26 ENSG00000200351
 .
 2634
 0.3
chr3_87010909_87011060 0.26 VGLL3
 vestigial like 3 (Drosophila)
 28868
 0.26
chr11_114178834_114179221 0.26 NNMT
 nicotinamide N-methyltransferase
 10154
 0.21
chr11_71847727_71847878 0.26 FOLR3
 folate receptor 3 (gamma)
 908
 0.38
chr4_77923892_77924043 0.25 SEPT11
 septin 11
 6932
 0.25
chr3_72059056_72059299 0.25 ENSG00000239250
 .
 182849
 0.03
chrX_48540228_48540452 0.25 WAS
 Wiskott-Aldrich syndrome
 1828
 0.24
chr2_38799437_38799781 0.25 HNRNPLL
 heterogeneous nuclear ribonucleoprotein L-like
 2631
 0.31
chr18_6629105_6629256 0.25 ENSG00000243591
 .
 27641
 0.19
chr12_104199945_104200104 0.25 RP11-650K20.2
13364
 0.14
chrX_19613547_19613843 0.25 SH3KBP1
 SH3-domain kinase binding protein 1
 74785
 0.11
chr18_53868353_53868679 0.25 ENSG00000201816
 .
 121691
 0.07
chr2_113944482_113944729 0.24 PSD4
 pleckstrin and Sec7 domain containing 4
 9252
 0.14
chr1_246756495_246756646 0.24 RP11-439E19.1
12605
 0.18
chr2_38816635_38816786 0.24 HNRNPLL
 heterogeneous nuclear ribonucleoprotein L-like
 10458
 0.2
chr4_153814372_153814523 0.24 ENSG00000252375
 .
 7671
 0.25
chr5_58564724_58564875 0.24 PDE4D
 phosphodiesterase 4D, cAMP-specific
 7146
 0.34
chr1_234896114_234896489 0.23 ENSG00000201638
 .
 77419
 0.1
chr18_426937_427124 0.23 RP11-720L2.2
2614
 0.34
chr2_181645689_181645840 0.22 ENSG00000264976
 .
 163831
 0.04
chr7_116702348_116702499 0.22 ST7-AS2
 ST7 antisense RNA 2
 12355
 0.19
chr10_37097557_37097708 0.22 ENSG00000207271
 .
 182566
 0.03
chr4_104013683_104013834 0.22 BDH2
 3-hydroxybutyrate dehydrogenase, type 2
 7228
 0.22
chr16_19946931_19947082 0.22 ENSG00000265524
 .
 45183
 0.14
chr7_7468485_7468636 0.22 COL28A1
 collagen, type XXVIII, alpha 1
 8506
 0.29
chr20_9291851_9292002 0.22 PLCB4
 phospholipase C, beta 4
 3479
 0.38
chr2_135025399_135025558 0.22 MGAT5
 mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase
 13648
 0.25
chr10_73857089_73857240 0.22 SPOCK2
 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2
 8374
 0.23
chr1_76668440_76668591 0.22 ST6GALNAC3
 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 3
 128111
 0.06
chrX_70858439_70858590 0.22 ENSG00000264855
 .
 12809
 0.19
chr1_184908112_184908263 0.22 FAM129A
 family with sequence similarity 129, member A
 35495
 0.18
chr15_101723886_101724154 0.22 CHSY1
 chondroitin sulfate synthase 1
 68117
 0.09
chr12_66008913_66009064 0.22 HMGA2
 high mobility group AT-hook 2
 208923
 0.02
chr7_28522211_28522362 0.21 CREB5
 cAMP responsive element binding protein 5
 8462
 0.32
chr12_62709538_62709689 0.21 USP15
 ubiquitin specific peptidase 15
 10237
 0.21
chr9_130217690_130217847 0.21 LRSAM1
 leucine rich repeat and sterile alpha motif containing 1
 3234
 0.16
chrX_70277041_70277192 0.21 SNX12
 sorting nexin 12
 11137
 0.13
chr17_2117955_2118176 0.21 SMG6
 SMG6 nonsense mediated mRNA decay factor
 422
 0.61
chr11_16085409_16085560 0.21 CTD-3096P4.1
40748
 0.2
chr19_24245928_24246079 0.21 ZNF254
 zinc finger protein 254
 23983
 0.22
chr9_91266890_91267190 0.21 ENSG00000265873
 .
 93780
 0.09
chr2_136673814_136673965 0.21 DARS
 aspartyl-tRNA synthetase
 4234
 0.24
chr8_125713884_125714035 0.21 MTSS1
 metastasis suppressor 1
 25898
 0.22
chr18_60002993_60003265 0.21 ENSG00000199867
 .
 5084
 0.19
chr12_15855178_15855329 0.21 EPS8
 epidermal growth factor receptor pathway substrate 8
 10674
 0.24
chr8_116474212_116474363 0.21 TRPS1
 trichorhinophalangeal syndrome I
 30161
 0.22
chr1_28297303_28297454 0.21 RP11-460I13.2
10674
 0.13
chr2_197173949_197174100 0.21 ENSG00000264627
 .
 19891
 0.2
chr14_50571585_50571736 0.21 VCPKMT
 valosin containing protein lysine (K) methyltransferase
 11615
 0.15
chr11_110890099_110890339 0.21 ENSG00000200168
 .
 20713
 0.27
chr12_42484877_42485028 0.21 ENSG00000222884
 .
 11389
 0.24
chr18_25696569_25696720 0.21 CDH2
 cadherin 2, type 1, N-cadherin (neuronal)
 19451
 0.3
chr19_41803776_41804158 0.21 ENSG00000239868
 .
 11368
 0.11
chr8_48504661_48504873 0.21 RP11-697N18.4
64808
 0.11
chr3_45957348_45957632 0.21 LZTFL1
 leucine zipper transcription factor-like 1
 44
 0.97
chr9_4621034_4621322 0.21 PPAPDC2
 phosphatidic acid phosphatase type 2 domain containing 2
 41120
 0.13
chr11_122085715_122085866 0.21 ENSG00000207994
 .
 62774
 0.1
chr4_2396569_2396720 0.20 ZFYVE28
 zinc finger, FYVE domain containing 28
 11748
 0.18
chr13_41230440_41230613 0.20 FOXO1
 forkhead box O1
 10208
 0.24
chr14_57854889_57855185 0.20 NAA30
 N(alpha)-acetyltransferase 30, NatC catalytic subunit
 2225
 0.4
chr15_65806614_65806765 0.20 DPP8
 dipeptidyl-peptidase 8
 1453
 0.32
chr9_92041929_92042366 0.20 SEMA4D
 sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D
 8399
 0.25
chr4_86433590_86433741 0.20 ARHGAP24
 Rho GTPase activating protein 24
 37274
 0.23
chr4_48375355_48375506 0.20 SLAIN2
 SLAIN motif family, member 2
 4488
 0.29
chr12_107256235_107256386 0.20 RP11-144F15.1
 Uncharacterized protein
 87614
 0.07
chr12_9514361_9514512 0.20 ENSG00000212440
 .
 75018
 0.08
chr15_40682509_40682797 0.20 KNSTRN
 kinetochore-localized astrin/SPAG5 binding protein
 7456
 0.09
chr2_225879744_225879975 0.20 ENSG00000263828
 .
 4602
 0.3
chr4_120236114_120236265 0.20 FABP2
 fatty acid binding protein 2, intestinal
 7356
 0.19
chr3_157094715_157094866 0.20 PTX3
 pentraxin 3, long
 59788
 0.13
chr2_113541634_113541892 0.20 IL1A
 interleukin 1, alpha
 404
 0.83
chr15_36648958_36649109 0.20 C15orf41
 chromosome 15 open reading frame 41
 222779
 0.02
chr3_108111491_108111642 0.20 HHLA2
 HERV-H LTR-associating 2
 39063
 0.18
chr8_116501913_116502064 0.20 TRPS1
 trichorhinophalangeal syndrome I
 2460
 0.37
chr6_83485563_83485714 0.20 RP11-445L13__B.3
156682
 0.04
chr7_80293760_80293911 0.20 CD36
 CD36 molecule (thrombospondin receptor)
 8857
 0.32
chr6_16729671_16729822 0.20 RP1-151F17.1
31623
 0.2
chr1_238817488_238817639 0.20 ENSG00000252371
 .
 328475
 0.01
chr3_129768526_129768677 0.20 ENSG00000263767
 .
 16213
 0.16
chr1_150750948_150751099 0.20 CTSS
 cathepsin S
 12590
 0.13
chr2_102356000_102356151 0.19 MAP4K4
 mitogen-activated protein kinase kinase kinase kinase 4
 41083
 0.2
chr16_12887485_12887636 0.19 CPPED1
 calcineurin-like phosphoesterase domain containing 1
 10148
 0.18
chr1_152013731_152013882 0.19 S100A11
 S100 calcium binding protein A11
 4295
 0.17
chr3_136370634_136370785 0.19 ENSG00000251708
 .
 18719
 0.2
chr3_81533853_81534004 0.19 ENSG00000222389
 .
 24699
 0.28
chr17_54517553_54517704 0.19 NOG
 noggin
 153432
 0.04
chr6_15206442_15206877 0.19 JARID2
 jumonji, AT rich interactive domain 2
 39868
 0.15
chr6_38238039_38238190 0.19 ENSG00000200706
 .
 63064
 0.13
chr1_182422913_182423064 0.19 RGSL1
 regulator of G-protein signaling like 1
 469
 0.85
chr5_153657053_153657204 0.19 ENSG00000221070
 .
 62558
 0.1
chr6_159285072_159285223 0.19 C6orf99
 chromosome 6 open reading frame 99
 5824
 0.2
chr6_139727785_139727936 0.19 CITED2
 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2
 32103
 0.22
chr10_126416114_126416281 0.19 FAM53B
 family with sequence similarity 53, member B
 15342
 0.16
chr5_100220016_100220167 0.19 ST8SIA4
 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4
 18827
 0.26
chr6_44818762_44818913 0.19 SUPT3H
 suppressor of Ty 3 homolog (S. cerevisiae)
 104410
 0.08
chr10_44318247_44318398 0.19 ZNF32
 zinc finger protein 32
 174018
 0.03
chr19_45241918_45242129 0.19 BCL3
 B-cell CLL/lymphoma 3
 9781
 0.11
chr2_52181809_52181960 0.19 ENSG00000202195
 .
 343249
 0.01
chr15_96381763_96381914 0.19 ENSG00000222076
 .
 92805
 0.1
chr7_131752106_131752257 0.19 ENSG00000252849
 .
 151100
 0.04
chr9_80035782_80035933 0.19 VPS13A
 vacuolar protein sorting 13 homolog A (S. cerevisiae)
 14973
 0.25
chr5_35781262_35781797 0.18 SPEF2
 sperm flagellar 2
 2259
 0.35
chr20_1968634_1968785 0.18 PDYN
 prodynorphin
 5685
 0.25
chr15_35983525_35983676 0.18 DPH6
 diphthamine biosynthesis 6
 145207
 0.05
chr1_151630880_151631031 0.18 SNX27
 sorting nexin family member 27
 19623
 0.09
chr4_19481051_19481202 0.18 ENSG00000251816
 .
 297647
 0.01
chr6_3869001_3869152 0.18 FAM50B
 family with sequence similarity 50, member B
 19454
 0.19
chr3_181414394_181414545 0.18 SOX2-OT
 SOX2 overlapping transcript (non-protein coding)
 2812
 0.32
chr16_86644741_86645021 0.18 FOXL1
 forkhead box L1
 32766
 0.15
chr5_112264098_112264423 0.18 REEP5
 receptor accessory protein 5
 6024
 0.15
chr6_54148057_54148208 0.18 TINAG
 tubulointerstitial nephritis antigen
 24632
 0.24
chr12_122314497_122314648 0.18 PSMD9
 proteasome (prosome, macropain) 26S subunit, non-ATPase, 9
 12065
 0.13
chr11_114007302_114007453 0.18 ENSG00000221112
 .
 49726
 0.14
chr16_17547341_17547635 0.18 XYLT1
 xylosyltransferase I
 17250
 0.31
chr3_99408032_99408183 0.18 ENSG00000263810
 .
 2308
 0.39
chr7_95225048_95225342 0.18 PDK4
 pyruvate dehydrogenase kinase, isozyme 4
 608
 0.53
chr7_51375507_51375658 0.18 COBL
 cordon-bleu WH2 repeat protein
 8586
 0.33
chr2_231658298_231658449 0.18 ENSG00000201044
 .
 41517
 0.14
chrX_3605542_3605693 0.18 PRKX
 protein kinase, X-linked
 26032
 0.16
chr2_37679552_37679783 0.18 ENSG00000253078
 .
 16916
 0.23
chr1_53673946_53674097 0.18 RP5-1024G6.2
5426
 0.11
chr5_58660727_58660878 0.18 PDE4D
 phosphodiesterase 4D, cAMP-specific
 8001
 0.33
chrX_38575159_38575310 0.18 MID1IP1
 MID1 interacting protein 1
 85451
 0.09
chr3_125029744_125030298 0.18 SLC12A8
 solute carrier family 12, member 8
 32000
 0.17
chr2_69381158_69381309 0.18 ENSG00000251850
 .
 27902
 0.16
chr8_48318431_48318582 0.18 SPIDR
 scaffolding protein involved in DNA repair
 34457
 0.22
chr12_91517941_91518092 0.18 LUM
 lumican
 12408
 0.22
chr7_156689439_156689590 0.18 LMBR1
 limb development membrane protein 1
 3590
 0.25
chr4_119266858_119267009 0.17 PRSS12
 protease, serine, 12 (neurotrypsin, motopsin)
 7225
 0.29
chr2_153551990_153552141 0.17 PRPF40A
 PRP40 pre-mRNA processing factor 40 homolog A (S. cerevisiae)
 21822
 0.21
chr11_65927584_65927735 0.17 ENSG00000238763
 .
 7567
 0.13
chr8_68284392_68284543 0.17 ARFGEF1
 ADP-ribosylation factor guanine nucleotide-exchange factor 1 (brefeldin A-inhibited)
 28555
 0.25
chr18_4320047_4320198 0.17 DLGAP1-AS5
 DLGAP1 antisense RNA 5
 55489
 0.17
chr9_79542182_79542333 0.17 PRUNE2
 prune homolog 2 (Drosophila)
 21254
 0.26
chr1_114343083_114343234 0.17 RP5-1073O3.2
11843
 0.15
chr3_71938564_71938715 0.17 ENSG00000239250
 .
 62311
 0.13
chr14_69609369_69609651 0.17 ENSG00000206768
 .
 1160
 0.51
chr9_132779554_132779797 0.17 FNBP1
 formin binding protein 1
 22529
 0.18
chr2_114657960_114658192 0.17 ACTR3
 ARP3 actin-related protein 3 homolog (yeast)
 9901
 0.23
chr2_8024667_8024818 0.17 ENSG00000221255
 .
 307770
 0.01
chr5_143397113_143397264 0.17 ENSG00000239390
 .
 123256
 0.06
chr11_108600903_108601054 0.17 DDX10
 DEAD (Asp-Glu-Ala-Asp) box polypeptide 10
 65129
 0.14
chr20_5126081_5126484 0.17 CDS2
 CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 2
 18671
 0.12
chr12_77047842_77047993 0.17 OSBPL8
 oxysterol binding protein-like 8
 94328
 0.08
chr16_15533271_15533422 0.17 C16orf45
 chromosome 16 open reading frame 45
 5014
 0.21
chr3_149219780_149219931 0.17 ENSG00000252581
 .
 23563
 0.17
chr8_98910268_98910419 0.17 MATN2
 matrilin 2
 10138
 0.24
chr6_57288673_57288824 0.17 ENSG00000212017
 .
 33818
 0.22
chr7_155486351_155486502 0.17 RBM33
 RNA binding motif protein 33
 7159
 0.25
chrX_46432280_46432556 0.17 CHST7
 carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 7
 801
 0.68
chr2_121529771_121529922 0.17 GLI2
 GLI family zinc finger 2
 20139
 0.27
chr2_216303134_216303285 0.17 AC012462.1
2233
 0.3
chr14_65387035_65387186 0.17 CHURC1
 churchill domain containing 1
 3618
 0.13
chr12_96428159_96428938 0.17 LTA4H
 leukotriene A4 hydrolase
 891
 0.53
chr13_99972638_99972796 0.17 GPR183
 G protein-coupled receptor 183
 13058
 0.19
chr12_93172479_93172630 0.17 PLEKHG7
 pleckstrin homology domain containing, family G (with RhoGef domain) member 7
 42243
 0.15
chr18_53827711_53827862 0.17 ENSG00000201816
 .
 80961
 0.12
chr10_126592017_126592168 0.17 RP11-298J20.4
13620
 0.17
chr19_54874397_54874958 0.17 LAIR1
 leukocyte-associated immunoglobulin-like receptor 1
 1737
 0.22
chr6_133052552_133052703 0.17 VNN3
 vanin 3
 2845
 0.19
chr3_156858863_156859014 0.17 ENSG00000201778
 .
 12399
 0.15
chr8_122258257_122258590 0.16 ENSG00000221644
 .
 59291
 0.16
chr15_42662964_42663115 0.16 CAPN3
 calpain 3, (p94)
 11254
 0.16
chr5_9196916_9197067 0.16 SEMA5A
 sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A
 68666
 0.13
chr1_182763113_182763264 0.16 NPL
 N-acetylneuraminate pyruvate lyase (dihydrodipicolinate synthase)
 297
 0.91
chr13_32709378_32709529 0.16 FRY
 furry homolog (Drosophila)
 74452
 0.11

Histogram of CRE-TSS distances for CREs targeted by :

Histogram of

Rank distribution of CRE target scores:

Histogram of target CRE score.

Distribution of target CREs across different genomic regions:

Weighted Piechart of Weighted Piechart of Weighted Piechart of

Network of associatons between targets according to the STRING database.

StringDB image

First level regulatory network of SOX21

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0010193 response to ozone(GO:0010193)
0.0 0.1 GO:0007221 positive regulation of transcription of Notch receptor target(GO:0007221)
0.0 0.1 GO:0055098 response to low-density lipoprotein particle(GO:0055098)
0.0 0.2 GO:0045197 establishment or maintenance of epithelial cell apical/basal polarity(GO:0045197)
0.0 0.1 GO:1903224 endodermal cell fate specification(GO:0001714) regulation of endodermal cell fate specification(GO:0042663) regulation of endodermal cell differentiation(GO:1903224)
0.0 0.1 GO:0031641 regulation of myelination(GO:0031641)
0.0 0.1 GO:0035385 Roundabout signaling pathway(GO:0035385)
0.0 0.1 GO:0070672 response to interleukin-15(GO:0070672)
0.0 0.1 GO:0007258 JUN phosphorylation(GO:0007258)
0.0 0.1 GO:0071220 response to bacterial lipoprotein(GO:0032493) response to bacterial lipopeptide(GO:0070339) cellular response to bacterial lipoprotein(GO:0071220) cellular response to bacterial lipopeptide(GO:0071221)
0.0 0.1 GO:0002313 mature B cell differentiation involved in immune response(GO:0002313)
0.0 0.1 GO:0032790 ribosome disassembly(GO:0032790)
0.0 0.1 GO:0021508 floor plate formation(GO:0021508)
0.0 0.1 GO:0018106 peptidyl-histidine phosphorylation(GO:0018106)
0.0 0.1 GO:1902745 positive regulation of lamellipodium assembly(GO:0010592) positive regulation of lamellipodium organization(GO:1902745)
0.0 0.1 GO:0070779 D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
0.0 0.1 GO:0045341 MHC class I biosynthetic process(GO:0045341) regulation of MHC class I biosynthetic process(GO:0045343)
0.0 0.1 GO:0001661 conditioned taste aversion(GO:0001661)
0.0 0.1 GO:0070208 protein heterotrimerization(GO:0070208)
0.0 0.1 GO:0001547 antral ovarian follicle growth(GO:0001547)
0.0 0.0 GO:0048541 Peyer's patch development(GO:0048541)
0.0 0.2 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.0 0.0 GO:0050862 positive regulation of T cell receptor signaling pathway(GO:0050862)
0.0 0.0 GO:0042118 endothelial cell activation(GO:0042118)
0.0 0.0 GO:0071436 sodium ion export(GO:0071436)
0.0 0.1 GO:0032455 nerve growth factor processing(GO:0032455)
0.0 0.1 GO:0008228 opsonization(GO:0008228)
0.0 0.1 GO:0032782 bile acid secretion(GO:0032782)
0.0 0.1 GO:0060314 regulation of ryanodine-sensitive calcium-release channel activity(GO:0060314)
0.0 0.0 GO:0050857 positive regulation of antigen receptor-mediated signaling pathway(GO:0050857)
0.0 0.1 GO:0045618 positive regulation of keratinocyte differentiation(GO:0045618)
0.0 0.0 GO:0051451 myoblast migration(GO:0051451)
0.0 0.0 GO:0060789 hair follicle placode formation(GO:0060789)
0.0 0.1 GO:0071731 response to nitric oxide(GO:0071731)
0.0 0.0 GO:0051305 chromosome movement towards spindle pole(GO:0051305)
0.0 0.1 GO:0048149 behavioral response to ethanol(GO:0048149)
0.0 0.0 GO:0032776 DNA methylation on cytosine(GO:0032776) C-5 methylation of cytosine(GO:0090116)
0.0 0.0 GO:0032288 myelin assembly(GO:0032288)
0.0 0.0 GO:0033152 immunoglobulin V(D)J recombination(GO:0033152)
0.0 0.0 GO:0002407 dendritic cell chemotaxis(GO:0002407) dendritic cell migration(GO:0036336)
0.0 0.0 GO:1903170 negative regulation of release of sequestered calcium ion into cytosol(GO:0051280) positive regulation of sequestering of calcium ion(GO:0051284) negative regulation of calcium ion transmembrane transport(GO:1903170)
0.0 0.0 GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.0 0.0 GO:0003078 obsolete regulation of natriuresis(GO:0003078)
0.0 0.1 GO:0043569 negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569)
0.0 0.0 GO:0031558 obsolete induction of apoptosis in response to chemical stimulus(GO:0031558)
0.0 0.0 GO:0042091 interleukin-10 biosynthetic process(GO:0042091) regulation of interleukin-10 biosynthetic process(GO:0045074)
0.0 0.1 GO:0060487 lung cell differentiation(GO:0060479) lung epithelial cell differentiation(GO:0060487)
0.0 0.0 GO:0042339 keratan sulfate metabolic process(GO:0042339)
0.0 0.1 GO:1901797 negative regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043518) negative regulation of signal transduction by p53 class mediator(GO:1901797)
0.0 0.1 GO:0006685 sphingomyelin catabolic process(GO:0006685)
0.0 0.0 GO:0007095 mitotic G2 DNA damage checkpoint(GO:0007095)
0.0 0.0 GO:0030263 apoptotic chromosome condensation(GO:0030263)
0.0 0.0 GO:0070682 proteasome regulatory particle assembly(GO:0070682)
0.0 0.0 GO:0006391 transcription initiation from mitochondrial promoter(GO:0006391)
0.0 0.0 GO:0032075 positive regulation of nuclease activity(GO:0032075)
0.0 0.0 GO:0035609 C-terminal protein deglutamylation(GO:0035609) protein side chain deglutamylation(GO:0035610)
0.0 0.1 GO:0035024 negative regulation of Rho protein signal transduction(GO:0035024)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0014701 junctional sarcoplasmic reticulum membrane(GO:0014701)
0.0 0.1 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.0 0.1 GO:0042272 nuclear RNA export factor complex(GO:0042272)
0.0 0.1 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.0 0.0 GO:0043083 synaptic cleft(GO:0043083)
0.0 0.1 GO:0005697 telomerase holoenzyme complex(GO:0005697)
0.0 0.1 GO:0046581 intercellular canaliculus(GO:0046581)
0.0 0.1 GO:0071437 invadopodium(GO:0071437)
0.0 0.1 GO:0045179 apical cortex(GO:0045179)
0.0 0.1 GO:0016342 catenin complex(GO:0016342)
0.0 0.0 GO:0031205 endoplasmic reticulum Sec complex(GO:0031205)
0.0 0.1 GO:0030056 hemidesmosome(GO:0030056)
0.0 0.1 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.0 0.0 GO:0005589 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.0 0.0 GO:0033270 paranode region of axon(GO:0033270)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0016909 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.0 0.1 GO:0010861 thyroid hormone receptor activator activity(GO:0010861)
0.0 0.1 GO:0050544 arachidonic acid binding(GO:0050544)
0.0 0.1 GO:0016833 oxo-acid-lyase activity(GO:0016833)
0.0 0.1 GO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.0 0.1 GO:0017159 pantetheine hydrolase activity(GO:0017159)
0.0 0.1 GO:0051637 obsolete Gram-positive bacterial cell surface binding(GO:0051637)
0.0 0.1 GO:0001517 N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517)
0.0 0.2 GO:0005149 interleukin-1 receptor binding(GO:0005149)
0.0 0.1 GO:0004301 epoxide hydrolase activity(GO:0004301)
0.0 0.1 GO:0042285 UDP-xylosyltransferase activity(GO:0035252) xylosyltransferase activity(GO:0042285)
0.0 0.1 GO:0030229 very-low-density lipoprotein particle receptor activity(GO:0030229)
0.0 0.1 GO:0008174 mRNA methyltransferase activity(GO:0008174)
0.0 0.1 GO:0004013 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.0 0.1 GO:0004596 peptide alpha-N-acetyltransferase activity(GO:0004596)
0.0 0.0 GO:0050693 LBD domain binding(GO:0050693)
0.0 0.1 GO:0043024 ribosomal small subunit binding(GO:0043024)
0.0 0.0 GO:0004060 arylamine N-acetyltransferase activity(GO:0004060)
0.0 0.1 GO:0001515 opioid peptide activity(GO:0001515)
0.0 0.1 GO:0045294 alpha-catenin binding(GO:0045294)
0.0 0.1 GO:0004690 cyclic nucleotide-dependent protein kinase activity(GO:0004690)
0.0 0.1 GO:0030297 transmembrane receptor protein tyrosine kinase activator activity(GO:0030297)
0.0 0.1 GO:0016494 C-X-C chemokine receptor activity(GO:0016494)
0.0 0.0 GO:0019959 C-X-C chemokine binding(GO:0019958) interleukin-8 binding(GO:0019959)
0.0 0.0 GO:0004946 bombesin receptor activity(GO:0004946)
0.0 0.1 GO:0019966 interleukin-1 binding(GO:0019966)
0.0 0.1 GO:0001727 lipid kinase activity(GO:0001727)
0.0 0.1 GO:0048495 Roundabout binding(GO:0048495)
0.0 0.0 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.0 0.1 GO:0030247 pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.0 0.1 GO:0005314 high-affinity glutamate transmembrane transporter activity(GO:0005314)
0.0 0.0 GO:0035198 miRNA binding(GO:0035198)
0.0 0.0 GO:0000033 alpha-1,3-mannosyltransferase activity(GO:0000033)
0.0 0.0 GO:0042978 ornithine decarboxylase activator activity(GO:0042978)
0.0 0.0 GO:0004677 DNA-dependent protein kinase activity(GO:0004677)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.0 PID CXCR3 PATHWAY CXCR3-mediated signaling events
0.0 0.0 PID TRAIL PATHWAY TRAIL signaling pathway
0.0 0.2 ST G ALPHA S PATHWAY G alpha s Pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.0 0.1 REACTOME ERKS ARE INACTIVATED Genes involved in ERKs are inactivated
0.0 0.0 REACTOME BINDING AND ENTRY OF HIV VIRION Genes involved in Binding and entry of HIV virion